ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LHNGMDCD_00001 6.05e-86 hxlR - - K - - - transcriptional
LHNGMDCD_00002 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LHNGMDCD_00003 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LHNGMDCD_00004 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_00005 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_00006 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
LHNGMDCD_00007 3.36e-91 nin - - S - - - Competence protein J (ComJ)
LHNGMDCD_00008 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHNGMDCD_00009 8.9e-22 - - - S - - - AAA domain
LHNGMDCD_00010 2.13e-113 - - - S - - - AAA domain
LHNGMDCD_00011 2.49e-27 - - - - - - - -
LHNGMDCD_00012 1.06e-57 - - - K - - - MarR family
LHNGMDCD_00013 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
LHNGMDCD_00014 1.11e-96 yckC - - S - - - membrane
LHNGMDCD_00017 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LHNGMDCD_00018 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHNGMDCD_00019 2.26e-123 yciC - - S - - - GTPases (G3E family)
LHNGMDCD_00020 2.72e-141 yciC - - S - - - GTPases (G3E family)
LHNGMDCD_00021 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
LHNGMDCD_00022 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
LHNGMDCD_00023 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LHNGMDCD_00024 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LHNGMDCD_00025 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHNGMDCD_00026 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHNGMDCD_00027 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LHNGMDCD_00028 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LHNGMDCD_00029 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LHNGMDCD_00030 3.3e-200 ycgS - - I - - - alpha/beta hydrolase fold
LHNGMDCD_00031 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
LHNGMDCD_00032 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
LHNGMDCD_00033 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LHNGMDCD_00034 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHNGMDCD_00035 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LHNGMDCD_00036 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LHNGMDCD_00037 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LHNGMDCD_00038 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LHNGMDCD_00039 5.64e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
LHNGMDCD_00040 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
LHNGMDCD_00041 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LHNGMDCD_00042 1.31e-140 tmrB - - S - - - AAA domain
LHNGMDCD_00043 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LHNGMDCD_00044 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LHNGMDCD_00045 2.67e-154 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_00046 4.4e-134 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_00047 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LHNGMDCD_00048 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LHNGMDCD_00049 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LHNGMDCD_00050 1.31e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LHNGMDCD_00051 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LHNGMDCD_00052 2.72e-105 ycgB - - - - - - -
LHNGMDCD_00053 0.0 ycgA - - S - - - Membrane
LHNGMDCD_00054 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LHNGMDCD_00055 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LHNGMDCD_00056 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LHNGMDCD_00057 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LHNGMDCD_00058 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHNGMDCD_00059 0.0 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
LHNGMDCD_00060 2.19e-86 - - - - ko:K19174 - ko00000,ko02048 -
LHNGMDCD_00061 3.83e-131 - - - V ko:K19173 - ko00000,ko02048 Type I site-specific restriction-modification system, R (Restriction) subunit and related
LHNGMDCD_00062 2.86e-193 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
LHNGMDCD_00063 8.5e-272 - - - EH ko:K19170 - ko00000,ko02048 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
LHNGMDCD_00064 3.14e-187 - - - EL ko:K19171 - ko00000,ko02048 AAA domain
LHNGMDCD_00065 1.9e-41 - - - S - - - DNA sulphur modification protein DndE
LHNGMDCD_00066 8.04e-181 - 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
LHNGMDCD_00067 1.72e-255 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
LHNGMDCD_00069 6.48e-288 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHNGMDCD_00070 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
LHNGMDCD_00071 9.34e-176 azlC - - E - - - AzlC protein
LHNGMDCD_00072 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
LHNGMDCD_00073 2.76e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LHNGMDCD_00074 1.74e-131 yrdC - - Q - - - Isochorismatase family
LHNGMDCD_00075 3.24e-75 - - - S - - - Protein of unknown function (DUF2568)
LHNGMDCD_00076 2.01e-118 yrdA - - S - - - DinB family
LHNGMDCD_00077 3.9e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
LHNGMDCD_00078 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LHNGMDCD_00079 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHNGMDCD_00080 1.96e-161 yrpD - - S - - - Domain of unknown function, YrpD
LHNGMDCD_00082 4.22e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LHNGMDCD_00083 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00084 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
LHNGMDCD_00085 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LHNGMDCD_00086 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_00087 1.19e-191 - - - S - - - Alpha beta hydrolase
LHNGMDCD_00088 6.61e-80 - - - T - - - sh3 domain protein
LHNGMDCD_00089 2.92e-81 - - - T - - - sh3 domain protein
LHNGMDCD_00090 6.62e-87 - - - E - - - Glyoxalase-like domain
LHNGMDCD_00091 4.19e-50 yraG - - - ko:K06440 - ko00000 -
LHNGMDCD_00092 9.61e-84 yraF - - M - - - Spore coat protein
LHNGMDCD_00093 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LHNGMDCD_00094 6.11e-36 yraE - - - ko:K06440 - ko00000 -
LHNGMDCD_00095 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
LHNGMDCD_00096 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LHNGMDCD_00097 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
LHNGMDCD_00098 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LHNGMDCD_00099 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LHNGMDCD_00100 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LHNGMDCD_00101 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LHNGMDCD_00102 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LHNGMDCD_00103 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
LHNGMDCD_00104 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LHNGMDCD_00105 0.0 levR - - K - - - PTS system fructose IIA component
LHNGMDCD_00106 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_00107 5.63e-137 yrhP - - E - - - LysE type translocator
LHNGMDCD_00108 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
LHNGMDCD_00109 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00110 3.51e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
LHNGMDCD_00111 2.18e-84 oatA - - I - - - Acyltransferase family
LHNGMDCD_00112 0.0 oatA - - I - - - Acyltransferase family
LHNGMDCD_00113 2.58e-58 yrhK - - S - - - YrhK-like protein
LHNGMDCD_00114 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LHNGMDCD_00115 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LHNGMDCD_00116 4.3e-124 yrhH - - Q - - - methyltransferase
LHNGMDCD_00117 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LHNGMDCD_00118 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LHNGMDCD_00120 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LHNGMDCD_00121 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LHNGMDCD_00122 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
LHNGMDCD_00123 5.71e-48 yrhC - - S - - - YrhC-like protein
LHNGMDCD_00124 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHNGMDCD_00125 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LHNGMDCD_00126 3.26e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHNGMDCD_00127 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LHNGMDCD_00128 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
LHNGMDCD_00129 2.02e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
LHNGMDCD_00130 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LHNGMDCD_00131 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LHNGMDCD_00132 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LHNGMDCD_00133 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LHNGMDCD_00134 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LHNGMDCD_00135 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LHNGMDCD_00136 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LHNGMDCD_00137 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
LHNGMDCD_00138 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHNGMDCD_00139 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
LHNGMDCD_00140 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LHNGMDCD_00141 1.25e-241 yrrI - - S - - - AI-2E family transporter
LHNGMDCD_00142 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHNGMDCD_00143 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHNGMDCD_00144 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_00145 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_00146 2.53e-149 - - GH19 M ko:K03791 - ko00000 Lysin motif
LHNGMDCD_00147 2.61e-73 - - - - - - - -
LHNGMDCD_00148 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LHNGMDCD_00149 3.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
LHNGMDCD_00151 1.31e-212 - - - S - - - Alpha/beta hydrolase family
LHNGMDCD_00152 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHNGMDCD_00153 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
LHNGMDCD_00154 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LHNGMDCD_00155 2.25e-59 ybfN - - - - - - -
LHNGMDCD_00156 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
LHNGMDCD_00157 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_00158 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LHNGMDCD_00159 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHNGMDCD_00160 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_00161 4.29e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHNGMDCD_00162 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LHNGMDCD_00164 3.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LHNGMDCD_00165 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHNGMDCD_00166 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LHNGMDCD_00167 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LHNGMDCD_00168 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LHNGMDCD_00169 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LHNGMDCD_00170 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_00171 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LHNGMDCD_00172 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
LHNGMDCD_00173 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHNGMDCD_00174 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_00175 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LHNGMDCD_00176 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
LHNGMDCD_00177 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LHNGMDCD_00178 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LHNGMDCD_00179 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LHNGMDCD_00180 2.26e-144 eamA1 - - EG - - - spore germination
LHNGMDCD_00181 4.94e-52 eamA1 - - EG - - - spore germination
LHNGMDCD_00182 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_00183 4.37e-214 ycbM - - T - - - Histidine kinase
LHNGMDCD_00184 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_00185 1.73e-149 - - - S - - - ABC-2 family transporter protein
LHNGMDCD_00186 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
LHNGMDCD_00187 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LHNGMDCD_00189 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHNGMDCD_00190 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_00191 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LHNGMDCD_00192 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LHNGMDCD_00194 1.89e-22 yycC - - K - - - YycC-like protein
LHNGMDCD_00195 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LHNGMDCD_00196 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LHNGMDCD_00197 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LHNGMDCD_00198 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LHNGMDCD_00199 1.14e-34 yybS - - S - - - membrane
LHNGMDCD_00200 4.15e-120 yybS - - S - - - membrane
LHNGMDCD_00202 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
LHNGMDCD_00203 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
LHNGMDCD_00204 1.3e-87 yybR - - K - - - Transcriptional regulator
LHNGMDCD_00205 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LHNGMDCD_00206 3.19e-90 - - - - - - - -
LHNGMDCD_00208 6.56e-68 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_00209 7.94e-200 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_00210 7.24e-141 - - - K - - - TipAS antibiotic-recognition domain
LHNGMDCD_00211 2.05e-183 - - - - - - - -
LHNGMDCD_00212 5.02e-87 - - - S - - - SnoaL-like domain
LHNGMDCD_00213 6.02e-157 yybG - - S - - - Pentapeptide repeat-containing protein
LHNGMDCD_00214 3.87e-132 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_00215 4.41e-105 - - - S - - - Metallo-beta-lactamase superfamily
LHNGMDCD_00216 4.54e-100 yybA - - K - - - transcriptional
LHNGMDCD_00217 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
LHNGMDCD_00218 1.55e-125 yyaS - - S ko:K07149 - ko00000 Membrane
LHNGMDCD_00219 3.81e-87 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LHNGMDCD_00220 2.28e-48 - - - S - - - YjbR
LHNGMDCD_00221 1.67e-134 yyaP - - H - - - RibD C-terminal domain
LHNGMDCD_00222 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
LHNGMDCD_00223 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LHNGMDCD_00224 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHNGMDCD_00225 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
LHNGMDCD_00226 3.01e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
LHNGMDCD_00227 4.69e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_00228 2.14e-154 ccpB - - K - - - Transcriptional regulator
LHNGMDCD_00229 2.65e-60 ccpB - - K - - - Transcriptional regulator
LHNGMDCD_00230 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LHNGMDCD_00231 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LHNGMDCD_00232 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LHNGMDCD_00233 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LHNGMDCD_00234 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LHNGMDCD_00235 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LHNGMDCD_00236 7.41e-45 yyzM - - S - - - protein conserved in bacteria
LHNGMDCD_00237 5.34e-227 yyaD - - S - - - Membrane
LHNGMDCD_00238 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
LHNGMDCD_00243 2.07e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_00244 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_00245 0.0 yycH - - S - - - protein conserved in bacteria
LHNGMDCD_00246 3.44e-200 yycI - - S - - - protein conserved in bacteria
LHNGMDCD_00247 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LHNGMDCD_00248 2.32e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHNGMDCD_00249 7.9e-241 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LHNGMDCD_00250 1.63e-43 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LHNGMDCD_00251 2.31e-54 sdpR - - K - - - transcriptional
LHNGMDCD_00252 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LHNGMDCD_00253 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
LHNGMDCD_00254 4.85e-119 - - - - - - - -
LHNGMDCD_00255 5.82e-20 - - - - - - - -
LHNGMDCD_00256 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LHNGMDCD_00257 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHNGMDCD_00258 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LHNGMDCD_00260 2.06e-204 - - - S - - - aspartate phosphatase
LHNGMDCD_00261 1.17e-18 - - - S - - - aspartate phosphatase
LHNGMDCD_00262 4.15e-108 yycN - - K - - - Acetyltransferase
LHNGMDCD_00263 3.06e-156 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LHNGMDCD_00264 2.71e-260 yycP - - - - - - -
LHNGMDCD_00265 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
LHNGMDCD_00267 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LHNGMDCD_00268 1.64e-89 - - - - - - - -
LHNGMDCD_00270 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LHNGMDCD_00272 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
LHNGMDCD_00273 1.59e-65 - - - L - - - Transposase
LHNGMDCD_00274 3.17e-176 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
LHNGMDCD_00275 3.99e-53 - - - - - - - -
LHNGMDCD_00277 1.07e-57 - - - S - - - transposition, DNA-mediated
LHNGMDCD_00278 6.23e-148 - - - S - - - HTH-like domain
LHNGMDCD_00279 0.0 - - - L - - - AAA ATPase domain
LHNGMDCD_00280 0.0 - - - L - - - Superfamily I DNA and RNA helicases
LHNGMDCD_00281 0.0 - - - V - - - Abi-like protein
LHNGMDCD_00282 6.83e-45 - - - - - - - -
LHNGMDCD_00292 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LHNGMDCD_00293 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LHNGMDCD_00294 1.19e-258 yaaN - - P - - - Belongs to the TelA family
LHNGMDCD_00295 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LHNGMDCD_00296 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LHNGMDCD_00297 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
LHNGMDCD_00298 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LHNGMDCD_00299 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LHNGMDCD_00300 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
LHNGMDCD_00301 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LHNGMDCD_00302 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LHNGMDCD_00303 2.84e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LHNGMDCD_00304 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LHNGMDCD_00305 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LHNGMDCD_00306 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHNGMDCD_00307 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LHNGMDCD_00308 1.18e-277 yabE - - T - - - protein conserved in bacteria
LHNGMDCD_00309 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LHNGMDCD_00310 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LHNGMDCD_00311 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
LHNGMDCD_00312 5.32e-53 veg - - S - - - protein conserved in bacteria
LHNGMDCD_00313 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
LHNGMDCD_00314 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LHNGMDCD_00315 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LHNGMDCD_00316 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LHNGMDCD_00317 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LHNGMDCD_00318 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LHNGMDCD_00319 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHNGMDCD_00320 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LHNGMDCD_00321 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LHNGMDCD_00322 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
LHNGMDCD_00323 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHNGMDCD_00324 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LHNGMDCD_00325 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_00326 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LHNGMDCD_00327 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LHNGMDCD_00328 1.91e-66 yabP - - S - - - Sporulation protein YabP
LHNGMDCD_00329 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
LHNGMDCD_00330 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LHNGMDCD_00331 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LHNGMDCD_00334 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LHNGMDCD_00335 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHNGMDCD_00336 6.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHNGMDCD_00337 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LHNGMDCD_00338 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LHNGMDCD_00339 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHNGMDCD_00340 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LHNGMDCD_00341 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHNGMDCD_00342 2.41e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LHNGMDCD_00343 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHNGMDCD_00345 2.09e-103 - - - - - - - -
LHNGMDCD_00346 7.6e-12 - - - S - - - Helix-turn-helix domain
LHNGMDCD_00347 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_00348 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_00349 5.33e-85 - - - - - - - -
LHNGMDCD_00350 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
LHNGMDCD_00352 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
LHNGMDCD_00353 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
LHNGMDCD_00354 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
LHNGMDCD_00356 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
LHNGMDCD_00357 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LHNGMDCD_00358 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHNGMDCD_00359 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LHNGMDCD_00360 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LHNGMDCD_00361 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LHNGMDCD_00362 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_00363 6.31e-51 - - - - - - - -
LHNGMDCD_00364 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHNGMDCD_00365 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
LHNGMDCD_00368 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
LHNGMDCD_00370 1.51e-18 cotW - - - ko:K06341 - ko00000 -
LHNGMDCD_00371 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LHNGMDCD_00372 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LHNGMDCD_00373 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LHNGMDCD_00374 2.09e-103 yjbX - - S - - - Spore coat protein
LHNGMDCD_00375 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LHNGMDCD_00376 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHNGMDCD_00377 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LHNGMDCD_00378 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LHNGMDCD_00379 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
LHNGMDCD_00380 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LHNGMDCD_00381 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LHNGMDCD_00382 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LHNGMDCD_00383 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LHNGMDCD_00384 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LHNGMDCD_00385 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHNGMDCD_00386 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHNGMDCD_00387 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LHNGMDCD_00388 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
LHNGMDCD_00389 7.02e-128 yjbK - - S - - - protein conserved in bacteria
LHNGMDCD_00390 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LHNGMDCD_00391 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LHNGMDCD_00392 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LHNGMDCD_00393 2.68e-28 - - - - - - - -
LHNGMDCD_00394 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LHNGMDCD_00395 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
LHNGMDCD_00396 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LHNGMDCD_00397 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
LHNGMDCD_00398 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LHNGMDCD_00399 1.41e-63 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_00400 2.77e-54 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_00401 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
LHNGMDCD_00402 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_00403 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_00404 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_00405 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_00406 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHNGMDCD_00407 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LHNGMDCD_00408 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
LHNGMDCD_00409 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_00410 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_00411 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LHNGMDCD_00412 2.82e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_00413 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_00414 9.48e-193 yjaZ - - O - - - Zn-dependent protease
LHNGMDCD_00415 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LHNGMDCD_00416 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHNGMDCD_00417 2.67e-38 yjzB - - - - - - -
LHNGMDCD_00418 8.86e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LHNGMDCD_00419 5.26e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LHNGMDCD_00420 5.2e-132 yjaV - - - - - - -
LHNGMDCD_00421 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
LHNGMDCD_00422 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
LHNGMDCD_00423 2.51e-39 yjzC - - S - - - YjzC-like protein
LHNGMDCD_00424 4.72e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LHNGMDCD_00425 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LHNGMDCD_00426 7.97e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LHNGMDCD_00427 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LHNGMDCD_00428 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LHNGMDCD_00429 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LHNGMDCD_00430 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LHNGMDCD_00431 1.61e-81 ylbA - - S - - - YugN-like family
LHNGMDCD_00432 1.53e-97 ylbB - - T - - - COG0517 FOG CBS domain
LHNGMDCD_00433 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
LHNGMDCD_00434 3.78e-88 ylbD - - S - - - Putative coat protein
LHNGMDCD_00435 1.73e-48 ylbE - - S - - - YlbE-like protein
LHNGMDCD_00436 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
LHNGMDCD_00437 4.36e-52 ylbG - - S - - - UPF0298 protein
LHNGMDCD_00438 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LHNGMDCD_00439 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LHNGMDCD_00440 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LHNGMDCD_00441 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LHNGMDCD_00442 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LHNGMDCD_00443 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
LHNGMDCD_00445 1.15e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LHNGMDCD_00446 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LHNGMDCD_00447 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LHNGMDCD_00448 1.33e-115 ylbP - - K - - - n-acetyltransferase
LHNGMDCD_00449 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHNGMDCD_00450 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LHNGMDCD_00451 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LHNGMDCD_00452 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LHNGMDCD_00453 3.42e-68 ftsL - - D - - - Essential cell division protein
LHNGMDCD_00454 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHNGMDCD_00455 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LHNGMDCD_00456 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHNGMDCD_00457 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LHNGMDCD_00458 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LHNGMDCD_00459 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHNGMDCD_00460 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LHNGMDCD_00461 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LHNGMDCD_00462 2.77e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LHNGMDCD_00463 1.35e-143 ylxW - - S - - - protein conserved in bacteria
LHNGMDCD_00464 8.67e-132 ylxX - - S - - - protein conserved in bacteria
LHNGMDCD_00465 5.37e-76 sbp - - S - - - small basic protein
LHNGMDCD_00466 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LHNGMDCD_00467 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHNGMDCD_00468 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LHNGMDCD_00470 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LHNGMDCD_00471 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_00472 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_00473 6.37e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LHNGMDCD_00474 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LHNGMDCD_00475 3.58e-51 ylmC - - S - - - sporulation protein
LHNGMDCD_00476 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LHNGMDCD_00477 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LHNGMDCD_00478 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LHNGMDCD_00479 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LHNGMDCD_00480 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
LHNGMDCD_00481 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LHNGMDCD_00482 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHNGMDCD_00483 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
LHNGMDCD_00484 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LHNGMDCD_00485 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LHNGMDCD_00486 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LHNGMDCD_00487 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LHNGMDCD_00488 1.39e-258 ycbU - - E - - - Selenocysteine lyase
LHNGMDCD_00489 1.45e-301 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LHNGMDCD_00490 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LHNGMDCD_00491 8.02e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LHNGMDCD_00492 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LHNGMDCD_00493 4.32e-78 - - - S - - - RDD family
LHNGMDCD_00494 7.13e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
LHNGMDCD_00495 6.18e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LHNGMDCD_00496 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LHNGMDCD_00497 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LHNGMDCD_00498 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_00499 2.9e-28 yccK - - C - - - Aldo keto reductase
LHNGMDCD_00500 4.58e-68 yccK - - C - - - Aldo keto reductase
LHNGMDCD_00501 6.38e-229 ycdA - - S - - - Domain of unknown function (DUF5105)
LHNGMDCD_00502 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00503 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00504 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LHNGMDCD_00505 1.65e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_00506 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LHNGMDCD_00507 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHNGMDCD_00508 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHNGMDCD_00509 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LHNGMDCD_00510 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LHNGMDCD_00511 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHNGMDCD_00512 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHNGMDCD_00513 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LHNGMDCD_00514 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LHNGMDCD_00515 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LHNGMDCD_00516 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LHNGMDCD_00517 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LHNGMDCD_00518 2.96e-245 yceH - - P - - - Belongs to the TelA family
LHNGMDCD_00519 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LHNGMDCD_00520 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LHNGMDCD_00522 5.36e-203 ybaS - - S - - - Na -dependent transporter
LHNGMDCD_00523 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
LHNGMDCD_00524 1.43e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_00525 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_00526 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LHNGMDCD_00527 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LHNGMDCD_00528 6.63e-270 ybbC - - S - - - protein conserved in bacteria
LHNGMDCD_00529 8.03e-21 ybbC - - S - - - protein conserved in bacteria
LHNGMDCD_00530 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LHNGMDCD_00531 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LHNGMDCD_00532 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_00533 3.14e-193 ybbH - - K - - - transcriptional
LHNGMDCD_00534 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LHNGMDCD_00535 8.99e-114 ybbJ - - J - - - acetyltransferase
LHNGMDCD_00536 9.88e-100 ybbK - - S - - - Protein of unknown function (DUF523)
LHNGMDCD_00542 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00543 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LHNGMDCD_00544 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHNGMDCD_00545 3.55e-291 ybbR - - S - - - protein conserved in bacteria
LHNGMDCD_00546 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHNGMDCD_00547 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LHNGMDCD_00550 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LHNGMDCD_00551 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHNGMDCD_00552 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
LHNGMDCD_00553 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LHNGMDCD_00554 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LHNGMDCD_00556 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LHNGMDCD_00557 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LHNGMDCD_00558 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LHNGMDCD_00559 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LHNGMDCD_00560 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LHNGMDCD_00561 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHNGMDCD_00562 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHNGMDCD_00563 1.05e-250 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHNGMDCD_00564 6.06e-61 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LHNGMDCD_00565 7.75e-258 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LHNGMDCD_00566 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_00567 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
LHNGMDCD_00568 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHNGMDCD_00569 3.19e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LHNGMDCD_00571 2.57e-10 - - - S - - - Protein of unknown function (DUF3918)
LHNGMDCD_00572 8.4e-42 yrzR - - - - - - -
LHNGMDCD_00573 2.79e-105 yrrD - - S - - - protein conserved in bacteria
LHNGMDCD_00574 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LHNGMDCD_00575 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
LHNGMDCD_00576 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LHNGMDCD_00577 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHNGMDCD_00578 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_00579 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LHNGMDCD_00580 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LHNGMDCD_00581 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LHNGMDCD_00582 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LHNGMDCD_00584 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LHNGMDCD_00585 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LHNGMDCD_00586 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHNGMDCD_00587 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LHNGMDCD_00588 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LHNGMDCD_00589 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LHNGMDCD_00590 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LHNGMDCD_00591 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LHNGMDCD_00592 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
LHNGMDCD_00593 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_00594 8.64e-145 yrbG - - S - - - membrane
LHNGMDCD_00595 2.16e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
LHNGMDCD_00596 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LHNGMDCD_00597 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LHNGMDCD_00598 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LHNGMDCD_00599 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
LHNGMDCD_00600 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LHNGMDCD_00601 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LHNGMDCD_00602 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LHNGMDCD_00603 0.0 csbX - - EGP - - - the major facilitator superfamily
LHNGMDCD_00604 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
LHNGMDCD_00605 1.91e-151 yrzF - - T - - - serine threonine protein kinase
LHNGMDCD_00607 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
LHNGMDCD_00609 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
LHNGMDCD_00610 3.51e-164 yebC - - K - - - transcriptional regulatory protein
LHNGMDCD_00611 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHNGMDCD_00612 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LHNGMDCD_00613 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LHNGMDCD_00614 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LHNGMDCD_00615 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LHNGMDCD_00616 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHNGMDCD_00617 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LHNGMDCD_00618 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LHNGMDCD_00619 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LHNGMDCD_00620 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LHNGMDCD_00621 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LHNGMDCD_00622 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LHNGMDCD_00623 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LHNGMDCD_00624 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LHNGMDCD_00625 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LHNGMDCD_00626 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LHNGMDCD_00627 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LHNGMDCD_00628 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LHNGMDCD_00629 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LHNGMDCD_00630 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LHNGMDCD_00631 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LHNGMDCD_00632 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LHNGMDCD_00633 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LHNGMDCD_00634 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LHNGMDCD_00635 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LHNGMDCD_00636 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LHNGMDCD_00637 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LHNGMDCD_00638 1.53e-35 - - - - - - - -
LHNGMDCD_00639 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LHNGMDCD_00640 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LHNGMDCD_00641 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LHNGMDCD_00642 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LHNGMDCD_00643 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LHNGMDCD_00644 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LHNGMDCD_00645 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
LHNGMDCD_00646 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LHNGMDCD_00647 4.77e-116 ysxD - - - - - - -
LHNGMDCD_00648 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LHNGMDCD_00649 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LHNGMDCD_00650 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LHNGMDCD_00651 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LHNGMDCD_00652 5.98e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LHNGMDCD_00653 2.62e-238 ysoA - - H - - - Tetratricopeptide repeat
LHNGMDCD_00654 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHNGMDCD_00655 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LHNGMDCD_00656 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LHNGMDCD_00657 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LHNGMDCD_00658 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LHNGMDCD_00659 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LHNGMDCD_00660 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LHNGMDCD_00662 3.28e-46 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LHNGMDCD_00663 3.36e-181 ysnF - - S - - - protein conserved in bacteria
LHNGMDCD_00664 9.38e-95 ytwI - - S - - - membrane
LHNGMDCD_00665 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
LHNGMDCD_00666 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LHNGMDCD_00667 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LHNGMDCD_00668 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LHNGMDCD_00669 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LHNGMDCD_00670 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LHNGMDCD_00671 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LHNGMDCD_00672 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LHNGMDCD_00673 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
LHNGMDCD_00674 5.12e-112 ytrI - - - - - - -
LHNGMDCD_00675 1.15e-39 - - - - - - - -
LHNGMDCD_00676 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LHNGMDCD_00677 2.15e-63 ytpI - - S - - - YtpI-like protein
LHNGMDCD_00678 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
LHNGMDCD_00679 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
LHNGMDCD_00680 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_00682 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LHNGMDCD_00683 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LHNGMDCD_00684 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LHNGMDCD_00685 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHNGMDCD_00687 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LHNGMDCD_00688 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LHNGMDCD_00689 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
LHNGMDCD_00690 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
LHNGMDCD_00691 8.23e-112 yteJ - - S - - - RDD family
LHNGMDCD_00692 3.25e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LHNGMDCD_00693 8.04e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHNGMDCD_00701 5.89e-58 - - - L - - - Phage integrase family
LHNGMDCD_00702 5.52e-31 - - - M - - - ArpU family transcriptional regulator
LHNGMDCD_00707 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHNGMDCD_00708 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LHNGMDCD_00709 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LHNGMDCD_00710 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LHNGMDCD_00711 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LHNGMDCD_00712 0.000711 - - - - - - - -
LHNGMDCD_00715 1.6e-94 - - - L - - - Phage integrase family
LHNGMDCD_00716 9.58e-67 - - - M - - - ArpU family transcriptional regulator
LHNGMDCD_00717 1.72e-151 - - - S - - - Domain of unknown function (DUF2479)
LHNGMDCD_00718 5.85e-164 - - - - - - - -
LHNGMDCD_00719 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
LHNGMDCD_00720 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LHNGMDCD_00721 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LHNGMDCD_00722 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LHNGMDCD_00724 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHNGMDCD_00725 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LHNGMDCD_00726 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LHNGMDCD_00727 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LHNGMDCD_00728 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LHNGMDCD_00729 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LHNGMDCD_00730 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LHNGMDCD_00731 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LHNGMDCD_00732 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_00733 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LHNGMDCD_00734 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LHNGMDCD_00736 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHNGMDCD_00737 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LHNGMDCD_00738 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LHNGMDCD_00739 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LHNGMDCD_00740 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
LHNGMDCD_00741 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHNGMDCD_00742 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LHNGMDCD_00743 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
LHNGMDCD_00744 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LHNGMDCD_00745 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LHNGMDCD_00746 1.1e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LHNGMDCD_00747 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LHNGMDCD_00748 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHNGMDCD_00749 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LHNGMDCD_00750 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LHNGMDCD_00751 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LHNGMDCD_00752 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LHNGMDCD_00753 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LHNGMDCD_00754 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LHNGMDCD_00755 2.92e-113 ywmA - - - - - - -
LHNGMDCD_00756 4.54e-45 ywzB - - S - - - membrane
LHNGMDCD_00757 6.59e-172 ywmB - - S - - - TATA-box binding
LHNGMDCD_00758 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHNGMDCD_00759 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LHNGMDCD_00760 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHNGMDCD_00761 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LHNGMDCD_00763 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LHNGMDCD_00764 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LHNGMDCD_00765 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_00766 8.55e-110 ywmF - - S - - - Peptidase M50
LHNGMDCD_00767 2.15e-19 csbD - - K - - - CsbD-like
LHNGMDCD_00768 0.000282 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
LHNGMDCD_00769 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LHNGMDCD_00770 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LHNGMDCD_00771 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LHNGMDCD_00772 4.58e-85 ywnA - - K - - - Transcriptional regulator
LHNGMDCD_00773 6.73e-19 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LHNGMDCD_00774 1.42e-112 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LHNGMDCD_00775 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
LHNGMDCD_00776 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LHNGMDCD_00777 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHNGMDCD_00778 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
LHNGMDCD_00779 6.7e-234 - - - M - - - NeuB family
LHNGMDCD_00780 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
LHNGMDCD_00781 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LHNGMDCD_00782 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LHNGMDCD_00783 9.05e-93 ywnJ - - S - - - VanZ like family
LHNGMDCD_00784 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LHNGMDCD_00785 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LHNGMDCD_00786 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LHNGMDCD_00787 7.16e-101 - - - - - - - -
LHNGMDCD_00788 1.04e-133 yjgF - - Q - - - Isochorismatase family
LHNGMDCD_00789 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
LHNGMDCD_00790 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LHNGMDCD_00791 3.25e-309 ywoF - - P - - - Right handed beta helix region
LHNGMDCD_00792 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_00793 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
LHNGMDCD_00794 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LHNGMDCD_00795 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LHNGMDCD_00796 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LHNGMDCD_00797 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LHNGMDCD_00798 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LHNGMDCD_00799 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LHNGMDCD_00800 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LHNGMDCD_00801 4.66e-186 ywpD - - T - - - Histidine kinase
LHNGMDCD_00802 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LHNGMDCD_00803 3.59e-88 ywpF - - S - - - YwpF-like protein
LHNGMDCD_00804 2.79e-40 ywpG - - - - - - -
LHNGMDCD_00805 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LHNGMDCD_00806 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHNGMDCD_00807 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHNGMDCD_00808 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LHNGMDCD_00809 0.0 ywqB - - S - - - SWIM zinc finger
LHNGMDCD_00810 3.6e-25 - - - - - - - -
LHNGMDCD_00811 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LHNGMDCD_00812 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LHNGMDCD_00813 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LHNGMDCD_00814 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHNGMDCD_00815 9.48e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
LHNGMDCD_00817 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
LHNGMDCD_00818 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LHNGMDCD_00819 2.5e-26 - - - - - - - -
LHNGMDCD_00820 1.3e-23 - - - - - - - -
LHNGMDCD_00821 4.93e-95 ywqJ - - S - - - Pre-toxin TG
LHNGMDCD_00822 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
LHNGMDCD_00824 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LHNGMDCD_00825 4.73e-209 - - - K - - - Transcriptional regulator
LHNGMDCD_00826 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
LHNGMDCD_00828 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LHNGMDCD_00829 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LHNGMDCD_00830 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LHNGMDCD_00831 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LHNGMDCD_00832 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
LHNGMDCD_00833 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHNGMDCD_00834 1e-17 - - - - - - - -
LHNGMDCD_00835 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
LHNGMDCD_00836 3.02e-44 cotB - - - ko:K06325 - ko00000 -
LHNGMDCD_00837 1.06e-162 ywrJ - - - - - - -
LHNGMDCD_00838 8.01e-263 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LHNGMDCD_00839 3.36e-218 alsR - - K - - - LysR substrate binding domain
LHNGMDCD_00840 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LHNGMDCD_00841 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LHNGMDCD_00842 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LHNGMDCD_00843 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
LHNGMDCD_00844 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
LHNGMDCD_00845 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LHNGMDCD_00846 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHNGMDCD_00847 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LHNGMDCD_00848 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LHNGMDCD_00849 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHNGMDCD_00850 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LHNGMDCD_00852 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LHNGMDCD_00853 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHNGMDCD_00854 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHNGMDCD_00855 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHNGMDCD_00856 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHNGMDCD_00857 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
LHNGMDCD_00858 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHNGMDCD_00859 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHNGMDCD_00860 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
LHNGMDCD_00861 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
LHNGMDCD_00862 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHNGMDCD_00863 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LHNGMDCD_00864 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LHNGMDCD_00865 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LHNGMDCD_00866 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LHNGMDCD_00867 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LHNGMDCD_00868 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LHNGMDCD_00869 1.09e-18 - - - S - - - Uncharacterized protein YkpC
LHNGMDCD_00870 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LHNGMDCD_00871 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
LHNGMDCD_00872 4.92e-285 - - - EGP - - - Major Facilitator Superfamily
LHNGMDCD_00873 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LHNGMDCD_00874 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LHNGMDCD_00875 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_00878 6.29e-100 yhjR - - S - - - Rubrerythrin
LHNGMDCD_00879 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LHNGMDCD_00880 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LHNGMDCD_00881 3.84e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LHNGMDCD_00882 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LHNGMDCD_00883 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
LHNGMDCD_00884 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LHNGMDCD_00885 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LHNGMDCD_00886 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LHNGMDCD_00887 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LHNGMDCD_00888 1.02e-46 gerPB - - S ko:K06300 - ko00000 cell differentiation
LHNGMDCD_00889 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LHNGMDCD_00890 6.21e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
LHNGMDCD_00891 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
LHNGMDCD_00892 3.11e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LHNGMDCD_00893 1.02e-74 yisL - - S - - - UPF0344 protein
LHNGMDCD_00894 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHNGMDCD_00896 5.04e-305 ygxB - - M - - - Conserved TM helix
LHNGMDCD_00897 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LHNGMDCD_00898 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LHNGMDCD_00899 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHNGMDCD_00900 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_00901 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHNGMDCD_00902 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_00903 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
LHNGMDCD_00904 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LHNGMDCD_00905 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_00906 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_00907 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
LHNGMDCD_00908 5.87e-256 yhdL - - S - - - Sigma factor regulator N-terminal
LHNGMDCD_00909 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_00910 1.12e-242 yhdN - - C - - - Aldo keto reductase
LHNGMDCD_00911 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LHNGMDCD_00912 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHNGMDCD_00913 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LHNGMDCD_00914 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LHNGMDCD_00915 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LHNGMDCD_00916 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LHNGMDCD_00917 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHNGMDCD_00918 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LHNGMDCD_00919 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHNGMDCD_00920 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
LHNGMDCD_00921 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LHNGMDCD_00922 9.4e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LHNGMDCD_00923 9.72e-192 nodB1 - - G - - - deacetylase
LHNGMDCD_00924 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LHNGMDCD_00925 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LHNGMDCD_00926 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
LHNGMDCD_00927 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHNGMDCD_00928 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHNGMDCD_00929 1.29e-140 yheG - - GM - - - NAD(P)H-binding
LHNGMDCD_00930 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LHNGMDCD_00931 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
LHNGMDCD_00932 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LHNGMDCD_00933 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
LHNGMDCD_00934 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
LHNGMDCD_00935 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
LHNGMDCD_00936 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
LHNGMDCD_00937 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
LHNGMDCD_00938 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LHNGMDCD_00939 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LHNGMDCD_00940 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LHNGMDCD_00941 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LHNGMDCD_00943 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
LHNGMDCD_00944 1.89e-35 - - - S - - - YhzD-like protein
LHNGMDCD_00945 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_00946 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LHNGMDCD_00947 8.42e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LHNGMDCD_00948 0.0 yhaN - - L - - - AAA domain
LHNGMDCD_00949 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LHNGMDCD_00950 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
LHNGMDCD_00951 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LHNGMDCD_00952 5.71e-116 yhaK - - S - - - Putative zincin peptidase
LHNGMDCD_00953 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
LHNGMDCD_00954 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LHNGMDCD_00955 1.74e-54 yhaH - - S - - - YtxH-like protein
LHNGMDCD_00956 3.36e-30 - - - - - - - -
LHNGMDCD_00957 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
LHNGMDCD_00958 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LHNGMDCD_00959 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LHNGMDCD_00960 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LHNGMDCD_00961 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LHNGMDCD_00962 2.89e-161 ecsC - - S - - - EcsC protein family
LHNGMDCD_00963 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LHNGMDCD_00964 2.7e-312 yhfA - - C - - - membrane
LHNGMDCD_00965 1e-44 - - - C - - - Rubrerythrin
LHNGMDCD_00966 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LHNGMDCD_00967 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHNGMDCD_00968 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LHNGMDCD_00969 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LHNGMDCD_00970 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LHNGMDCD_00971 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_00972 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LHNGMDCD_00973 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LHNGMDCD_00974 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
LHNGMDCD_00975 1.55e-252 yhfE - - G - - - peptidase M42
LHNGMDCD_00976 1.79e-92 - - - S - - - ASCH
LHNGMDCD_00977 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHNGMDCD_00978 1.63e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LHNGMDCD_00979 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LHNGMDCD_00980 1.01e-141 yhfK - - GM - - - NmrA-like family
LHNGMDCD_00981 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LHNGMDCD_00982 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LHNGMDCD_00983 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LHNGMDCD_00984 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHNGMDCD_00985 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LHNGMDCD_00986 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LHNGMDCD_00987 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LHNGMDCD_00988 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LHNGMDCD_00989 1.38e-73 swrA - - S - - - Swarming motility protein
LHNGMDCD_00990 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHNGMDCD_00991 3.03e-295 yvkA - - P - - - -transporter
LHNGMDCD_00992 1.43e-131 yvkB - - K - - - Transcriptional regulator
LHNGMDCD_00993 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LHNGMDCD_00994 2.54e-42 csbA - - S - - - protein conserved in bacteria
LHNGMDCD_00995 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LHNGMDCD_00996 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LHNGMDCD_00997 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LHNGMDCD_00998 2.25e-45 yvkN - - - - - - -
LHNGMDCD_00999 8.09e-65 yvlA - - - - - - -
LHNGMDCD_01000 5.54e-219 yvlB - - S - - - Putative adhesin
LHNGMDCD_01001 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LHNGMDCD_01002 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LHNGMDCD_01003 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LHNGMDCD_01004 3.45e-137 bdbD - - O - - - Thioredoxin
LHNGMDCD_01005 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LHNGMDCD_01006 6.7e-139 yvgT - - S - - - membrane
LHNGMDCD_01008 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHNGMDCD_01009 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LHNGMDCD_01010 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LHNGMDCD_01011 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LHNGMDCD_01012 9.32e-112 yvgO - - - - - - -
LHNGMDCD_01013 6.19e-201 yvgN - - S - - - reductase
LHNGMDCD_01014 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LHNGMDCD_01015 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LHNGMDCD_01016 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LHNGMDCD_01018 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LHNGMDCD_01019 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHNGMDCD_01020 5.44e-74 yuzD - - S - - - protein conserved in bacteria
LHNGMDCD_01021 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LHNGMDCD_01022 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LHNGMDCD_01023 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LHNGMDCD_01024 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LHNGMDCD_01025 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LHNGMDCD_01026 2.57e-252 yutH - - S - - - Spore coat protein
LHNGMDCD_01027 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LHNGMDCD_01028 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LHNGMDCD_01029 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
LHNGMDCD_01030 3.2e-63 yutD - - S - - - protein conserved in bacteria
LHNGMDCD_01031 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHNGMDCD_01032 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LHNGMDCD_01033 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LHNGMDCD_01034 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LHNGMDCD_01035 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
LHNGMDCD_01036 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHNGMDCD_01037 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LHNGMDCD_01038 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
LHNGMDCD_01039 1.07e-79 yunG - - - - - - -
LHNGMDCD_01040 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LHNGMDCD_01041 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LHNGMDCD_01042 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
LHNGMDCD_01043 4.37e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LHNGMDCD_01044 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LHNGMDCD_01045 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LHNGMDCD_01047 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHNGMDCD_01048 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LHNGMDCD_01049 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LHNGMDCD_01050 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LHNGMDCD_01051 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LHNGMDCD_01052 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LHNGMDCD_01053 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LHNGMDCD_01054 4.82e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LHNGMDCD_01055 4.42e-216 bsn - - L - - - Ribonuclease
LHNGMDCD_01056 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_01057 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LHNGMDCD_01058 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LHNGMDCD_01059 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LHNGMDCD_01060 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LHNGMDCD_01061 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHNGMDCD_01062 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LHNGMDCD_01063 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LHNGMDCD_01064 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LHNGMDCD_01065 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LHNGMDCD_01067 3.35e-56 - - - - - - - -
LHNGMDCD_01068 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
LHNGMDCD_01069 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LHNGMDCD_01070 1.04e-122 gerD - - - ko:K06294 - ko00000 -
LHNGMDCD_01071 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LHNGMDCD_01072 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHNGMDCD_01073 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
LHNGMDCD_01074 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
LHNGMDCD_01075 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LHNGMDCD_01076 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LHNGMDCD_01077 2.51e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LHNGMDCD_01078 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHNGMDCD_01079 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHNGMDCD_01080 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LHNGMDCD_01081 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LHNGMDCD_01082 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHNGMDCD_01083 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LHNGMDCD_01084 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LHNGMDCD_01085 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LHNGMDCD_01086 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LHNGMDCD_01087 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LHNGMDCD_01088 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LHNGMDCD_01089 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LHNGMDCD_01090 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LHNGMDCD_01091 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LHNGMDCD_01092 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LHNGMDCD_01093 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LHNGMDCD_01094 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LHNGMDCD_01095 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LHNGMDCD_01096 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHNGMDCD_01097 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LHNGMDCD_01098 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LHNGMDCD_01099 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LHNGMDCD_01100 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LHNGMDCD_01101 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LHNGMDCD_01102 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LHNGMDCD_01103 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LHNGMDCD_01104 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LHNGMDCD_01105 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LHNGMDCD_01106 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LHNGMDCD_01107 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LHNGMDCD_01108 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LHNGMDCD_01109 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LHNGMDCD_01110 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LHNGMDCD_01111 1.83e-230 ybaC - - S - - - Alpha/beta hydrolase family
LHNGMDCD_01112 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LHNGMDCD_01113 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LHNGMDCD_01114 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LHNGMDCD_01115 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LHNGMDCD_01116 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LHNGMDCD_01117 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHNGMDCD_01118 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LHNGMDCD_01119 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LHNGMDCD_01120 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LHNGMDCD_01121 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LHNGMDCD_01122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LHNGMDCD_01123 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LHNGMDCD_01124 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LHNGMDCD_01125 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LHNGMDCD_01126 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LHNGMDCD_01127 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LHNGMDCD_01128 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHNGMDCD_01129 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LHNGMDCD_01130 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LHNGMDCD_01131 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LHNGMDCD_01132 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHNGMDCD_01133 1.82e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LHNGMDCD_01134 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LHNGMDCD_01135 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LHNGMDCD_01136 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LHNGMDCD_01137 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LHNGMDCD_01138 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LHNGMDCD_01139 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LHNGMDCD_01140 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LHNGMDCD_01141 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LHNGMDCD_01143 0.0 rocB - - E - - - arginine degradation protein
LHNGMDCD_01144 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LHNGMDCD_01145 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHNGMDCD_01146 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHNGMDCD_01147 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LHNGMDCD_01148 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LHNGMDCD_01149 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHNGMDCD_01150 1.06e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHNGMDCD_01151 4.35e-32 yqzJ - - - - - - -
LHNGMDCD_01152 1.47e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHNGMDCD_01153 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
LHNGMDCD_01154 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LHNGMDCD_01155 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LHNGMDCD_01156 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LHNGMDCD_01158 9.84e-128 yqjB - - S - - - protein conserved in bacteria
LHNGMDCD_01159 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LHNGMDCD_01160 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHNGMDCD_01161 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHNGMDCD_01162 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHNGMDCD_01163 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
LHNGMDCD_01164 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LHNGMDCD_01165 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_01166 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
LHNGMDCD_01167 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHNGMDCD_01168 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHNGMDCD_01169 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHNGMDCD_01170 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHNGMDCD_01171 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LHNGMDCD_01172 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHNGMDCD_01173 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LHNGMDCD_01174 0.0 bkdR - - KT - - - Transcriptional regulator
LHNGMDCD_01175 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
LHNGMDCD_01176 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LHNGMDCD_01177 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LHNGMDCD_01178 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHNGMDCD_01179 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LHNGMDCD_01180 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LHNGMDCD_01181 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHNGMDCD_01182 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LHNGMDCD_01183 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LHNGMDCD_01184 4.74e-37 - - - - - - - -
LHNGMDCD_01185 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LHNGMDCD_01187 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LHNGMDCD_01188 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LHNGMDCD_01189 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LHNGMDCD_01190 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LHNGMDCD_01191 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LHNGMDCD_01192 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LHNGMDCD_01193 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHNGMDCD_01194 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHNGMDCD_01195 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LHNGMDCD_01196 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LHNGMDCD_01197 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LHNGMDCD_01198 9.55e-88 yqhY - - S - - - protein conserved in bacteria
LHNGMDCD_01199 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LHNGMDCD_01200 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LHNGMDCD_01201 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LHNGMDCD_01202 7.6e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LHNGMDCD_01203 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LHNGMDCD_01204 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LHNGMDCD_01205 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LHNGMDCD_01206 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LHNGMDCD_01207 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LHNGMDCD_01208 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LHNGMDCD_01209 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LHNGMDCD_01210 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LHNGMDCD_01211 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LHNGMDCD_01212 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
LHNGMDCD_01213 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
LHNGMDCD_01214 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
LHNGMDCD_01215 5.18e-81 yqhP - - - - - - -
LHNGMDCD_01216 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LHNGMDCD_01217 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LHNGMDCD_01218 2.63e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LHNGMDCD_01219 2.51e-81 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LHNGMDCD_01223 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
LHNGMDCD_01224 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LHNGMDCD_01225 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHNGMDCD_01226 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHNGMDCD_01227 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LHNGMDCD_01228 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LHNGMDCD_01229 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHNGMDCD_01230 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHNGMDCD_01231 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHNGMDCD_01232 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01233 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01234 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LHNGMDCD_01235 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
LHNGMDCD_01236 2.13e-228 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LHNGMDCD_01237 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
LHNGMDCD_01239 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LHNGMDCD_01240 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LHNGMDCD_01241 4.28e-163 - - - - - - - -
LHNGMDCD_01242 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LHNGMDCD_01243 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
LHNGMDCD_01244 3.54e-156 ydhC - - K - - - FCD
LHNGMDCD_01245 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LHNGMDCD_01246 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LHNGMDCD_01247 1.9e-89 - - - K - - - Winged helix DNA-binding domain
LHNGMDCD_01248 6.42e-147 ydgI - - C - - - nitroreductase
LHNGMDCD_01249 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LHNGMDCD_01250 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHNGMDCD_01251 6.94e-117 - - - S - - - DinB family
LHNGMDCD_01252 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_01253 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LHNGMDCD_01254 8.04e-111 yycN - - K - - - Acetyltransferase
LHNGMDCD_01255 5.76e-70 - - - S - - - DoxX-like family
LHNGMDCD_01256 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
LHNGMDCD_01257 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
LHNGMDCD_01258 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
LHNGMDCD_01259 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHNGMDCD_01260 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_01261 5e-152 ydfR - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_01263 3.75e-39 - - - - - - - -
LHNGMDCD_01264 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
LHNGMDCD_01265 2.1e-71 ydfQ - - CO - - - Thioredoxin
LHNGMDCD_01266 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
LHNGMDCD_01267 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHNGMDCD_01268 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LHNGMDCD_01269 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHNGMDCD_01270 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
LHNGMDCD_01271 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LHNGMDCD_01272 4.26e-220 - - - S - - - Alpha/beta hydrolase family
LHNGMDCD_01275 2.73e-28 xhlB - - S - - - SPP1 phage holin
LHNGMDCD_01276 3.63e-43 - - - K - - - sigma factor activity
LHNGMDCD_01277 2.88e-185 ybfI - - K - - - AraC-like ligand binding domain
LHNGMDCD_01278 5.01e-133 ybfH - - EG - - - EamA-like transporter family
LHNGMDCD_01279 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LHNGMDCD_01282 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_01283 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_01284 8.65e-202 ybfA - - K - - - FR47-like protein
LHNGMDCD_01285 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
LHNGMDCD_01286 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LHNGMDCD_01287 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LHNGMDCD_01288 0.0 ybeC - - E - - - amino acid
LHNGMDCD_01289 1.28e-37 ybyB - - - - - - -
LHNGMDCD_01290 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LHNGMDCD_01291 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
LHNGMDCD_01292 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
LHNGMDCD_01293 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LHNGMDCD_01294 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
LHNGMDCD_01295 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
LHNGMDCD_01296 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LHNGMDCD_01297 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LHNGMDCD_01298 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LHNGMDCD_01299 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LHNGMDCD_01300 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LHNGMDCD_01301 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LHNGMDCD_01302 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LHNGMDCD_01303 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LHNGMDCD_01304 3.7e-111 - - - - - - - -
LHNGMDCD_01305 0.0 - - - - - - - -
LHNGMDCD_01307 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LHNGMDCD_01308 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LHNGMDCD_01309 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LHNGMDCD_01310 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LHNGMDCD_01311 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHNGMDCD_01312 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LHNGMDCD_01313 5.52e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LHNGMDCD_01314 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LHNGMDCD_01315 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LHNGMDCD_01316 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LHNGMDCD_01317 7.42e-29 - - - - - - - -
LHNGMDCD_01318 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_01319 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
LHNGMDCD_01320 3.67e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_01321 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LHNGMDCD_01322 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHNGMDCD_01323 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LHNGMDCD_01324 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LHNGMDCD_01325 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LHNGMDCD_01326 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LHNGMDCD_01327 1.54e-221 yvdE - - K - - - Transcriptional regulator
LHNGMDCD_01328 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
LHNGMDCD_01329 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LHNGMDCD_01330 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LHNGMDCD_01331 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LHNGMDCD_01332 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
LHNGMDCD_01333 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LHNGMDCD_01334 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHNGMDCD_01335 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHNGMDCD_01336 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LHNGMDCD_01338 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
LHNGMDCD_01339 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LHNGMDCD_01340 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LHNGMDCD_01341 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
LHNGMDCD_01342 0.0 ybeC - - E - - - amino acid
LHNGMDCD_01343 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LHNGMDCD_01344 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LHNGMDCD_01345 3.77e-79 pbpE - - V - - - Beta-lactamase
LHNGMDCD_01346 2.17e-224 pbpE - - V - - - Beta-lactamase
LHNGMDCD_01347 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LHNGMDCD_01348 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
LHNGMDCD_01349 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
LHNGMDCD_01350 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LHNGMDCD_01352 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LHNGMDCD_01353 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LHNGMDCD_01354 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LHNGMDCD_01355 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LHNGMDCD_01356 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LHNGMDCD_01357 5.25e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LHNGMDCD_01358 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHNGMDCD_01359 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHNGMDCD_01360 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LHNGMDCD_01361 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LHNGMDCD_01362 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LHNGMDCD_01363 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHNGMDCD_01364 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_01365 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LHNGMDCD_01366 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LHNGMDCD_01367 1.06e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LHNGMDCD_01368 3.07e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LHNGMDCD_01369 2.32e-43 yvfG - - S - - - YvfG protein
LHNGMDCD_01370 7.05e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LHNGMDCD_01371 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LHNGMDCD_01372 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LHNGMDCD_01373 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_01374 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LHNGMDCD_01375 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LHNGMDCD_01376 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LHNGMDCD_01377 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
LHNGMDCD_01378 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LHNGMDCD_01379 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
LHNGMDCD_01380 8.47e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
LHNGMDCD_01381 1.1e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LHNGMDCD_01382 8.31e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LHNGMDCD_01383 1.09e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_01384 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_01385 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
LHNGMDCD_01386 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
LHNGMDCD_01387 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LHNGMDCD_01388 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LHNGMDCD_01389 6.88e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LHNGMDCD_01390 2.7e-187 - - - S - - - Glycosyl hydrolase
LHNGMDCD_01391 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_01392 5.59e-198 yvbV - - EG - - - EamA-like transporter family
LHNGMDCD_01393 1.99e-205 yvbU - - K - - - Transcriptional regulator
LHNGMDCD_01394 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHNGMDCD_01395 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LHNGMDCD_01396 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_01397 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LHNGMDCD_01398 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHNGMDCD_01399 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LHNGMDCD_01400 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LHNGMDCD_01401 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LHNGMDCD_01402 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LHNGMDCD_01403 9.77e-106 yvbK - - K - - - acetyltransferase
LHNGMDCD_01404 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LHNGMDCD_01405 2.66e-155 yvbI - - M - - - Membrane
LHNGMDCD_01406 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
LHNGMDCD_01407 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LHNGMDCD_01408 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LHNGMDCD_01409 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LHNGMDCD_01410 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHNGMDCD_01411 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LHNGMDCD_01412 1.13e-135 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHNGMDCD_01413 3.28e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LHNGMDCD_01414 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LHNGMDCD_01415 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHNGMDCD_01416 7.61e-217 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LHNGMDCD_01417 3.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LHNGMDCD_01418 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_01419 3.85e-72 yvaP - - K - - - transcriptional
LHNGMDCD_01420 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LHNGMDCD_01421 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LHNGMDCD_01422 4.9e-48 yvzC - - K - - - transcriptional
LHNGMDCD_01423 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
LHNGMDCD_01424 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LHNGMDCD_01425 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LHNGMDCD_01426 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LHNGMDCD_01427 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LHNGMDCD_01429 2.09e-81 - - - S - - - Phage integrase family
LHNGMDCD_01430 4.26e-43 - - - S - - - Phage integrase family
LHNGMDCD_01431 5.28e-79 - - - - - - - -
LHNGMDCD_01434 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_01435 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
LHNGMDCD_01438 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LHNGMDCD_01439 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
LHNGMDCD_01440 1.76e-10 - - - - - - - -
LHNGMDCD_01443 2.78e-08 - - - - - - - -
LHNGMDCD_01449 1.76e-59 - - - S - - - dUTPase
LHNGMDCD_01451 1.12e-07 - - - S - - - YopX protein
LHNGMDCD_01453 0.0 - - - IQ ko:K15641,ko:K16398,ko:K16417,ko:K20788 ko01052,map01052 ko00000,ko00001,ko01008 PKS_KR
LHNGMDCD_01454 1.42e-56 - - - S - - - MepB protein
LHNGMDCD_01455 8.33e-58 - - - S - - - Metallo-beta-lactamase superfamily
LHNGMDCD_01456 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LHNGMDCD_01457 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
LHNGMDCD_01458 1.34e-120 ybcF - - P - - - carbonic anhydrase
LHNGMDCD_01459 1.13e-63 - - - - - - - -
LHNGMDCD_01460 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
LHNGMDCD_01461 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
LHNGMDCD_01462 1.89e-70 - - - T - - - His Kinase A (phospho-acceptor) domain
LHNGMDCD_01463 2.05e-131 - - - T - - - His Kinase A (phospho-acceptor) domain
LHNGMDCD_01465 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
LHNGMDCD_01466 1.49e-192 ybdN - - - - - - -
LHNGMDCD_01467 4.65e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
LHNGMDCD_01468 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_01469 6.29e-42 - - - L - - - COG3666 Transposase and inactivated derivatives
LHNGMDCD_01470 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LHNGMDCD_01471 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LHNGMDCD_01472 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_01473 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LHNGMDCD_01474 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LHNGMDCD_01475 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LHNGMDCD_01476 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LHNGMDCD_01477 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LHNGMDCD_01478 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LHNGMDCD_01479 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_01480 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LHNGMDCD_01481 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
LHNGMDCD_01482 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LHNGMDCD_01483 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LHNGMDCD_01484 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LHNGMDCD_01485 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
LHNGMDCD_01486 1.1e-103 yffB - - K - - - Transcriptional regulator
LHNGMDCD_01487 1.54e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
LHNGMDCD_01489 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHNGMDCD_01490 1.45e-93 ywhA - - K - - - Transcriptional regulator
LHNGMDCD_01491 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LHNGMDCD_01492 3.29e-154 ywhC - - S - - - Peptidase family M50
LHNGMDCD_01493 1.92e-123 ywhD - - S - - - YwhD family
LHNGMDCD_01494 2.1e-64 - - - - - - - -
LHNGMDCD_01495 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHNGMDCD_01496 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LHNGMDCD_01497 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LHNGMDCD_01498 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
LHNGMDCD_01500 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHNGMDCD_01501 1.72e-156 ywhK - - CO - - - amine dehydrogenase activity
LHNGMDCD_01502 1.57e-96 ywhK - - CO - - - amine dehydrogenase activity
LHNGMDCD_01503 1.31e-303 ywhL - - CO - - - amine dehydrogenase activity
LHNGMDCD_01505 1.17e-315 - - - L - - - Peptidase, M16
LHNGMDCD_01506 3.84e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
LHNGMDCD_01507 1.81e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
LHNGMDCD_01508 5.02e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LHNGMDCD_01510 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
LHNGMDCD_01511 3.71e-12 - - - S - - - Bacteriocin subtilosin A
LHNGMDCD_01512 5.42e-95 ywiB - - S - - - protein conserved in bacteria
LHNGMDCD_01513 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LHNGMDCD_01518 1.44e-06 - - - L - - - COG3843 Type IV secretory pathway, VirD2 components (relaxase)
LHNGMDCD_01519 5.58e-42 - - - U - - - Relaxase/Mobilisation nuclease domain
LHNGMDCD_01520 1.02e-41 - - - S - - - Bacterial mobilisation protein (MobC)
LHNGMDCD_01521 8.81e-171 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
LHNGMDCD_01524 2.53e-223 - - - L - - - Replication protein
LHNGMDCD_01525 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LHNGMDCD_01526 2.46e-67 - - - - - - - -
LHNGMDCD_01527 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LHNGMDCD_01528 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LHNGMDCD_01529 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LHNGMDCD_01530 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
LHNGMDCD_01531 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LHNGMDCD_01532 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LHNGMDCD_01533 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LHNGMDCD_01534 6.92e-92 yviE - - - - - - -
LHNGMDCD_01535 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LHNGMDCD_01536 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LHNGMDCD_01537 7.06e-102 yvyG - - NOU - - - FlgN protein
LHNGMDCD_01538 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LHNGMDCD_01539 1.06e-95 yvyF - - S - - - flagellar protein
LHNGMDCD_01540 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LHNGMDCD_01541 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LHNGMDCD_01542 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LHNGMDCD_01543 1.24e-198 degV - - S - - - protein conserved in bacteria
LHNGMDCD_01544 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_01545 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LHNGMDCD_01546 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LHNGMDCD_01547 1.23e-151 - - - K - - - Transcriptional regulator
LHNGMDCD_01551 3.12e-50 - - - S - - - Psort location CytoplasmicMembrane, score
LHNGMDCD_01554 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_01556 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LHNGMDCD_01557 7.15e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LHNGMDCD_01558 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LHNGMDCD_01559 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LHNGMDCD_01560 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LHNGMDCD_01562 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHNGMDCD_01563 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LHNGMDCD_01564 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_01565 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LHNGMDCD_01566 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LHNGMDCD_01567 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_01568 6.21e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_01569 5.86e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LHNGMDCD_01570 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_01571 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHNGMDCD_01572 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LHNGMDCD_01573 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01574 1.97e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LHNGMDCD_01575 2.21e-228 ykvZ - - K - - - Transcriptional regulator
LHNGMDCD_01576 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LHNGMDCD_01577 3.99e-09 - - - - - - - -
LHNGMDCD_01578 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LHNGMDCD_01579 1.12e-114 stoA - - CO - - - thiol-disulfide
LHNGMDCD_01580 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_01581 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LHNGMDCD_01582 2.6e-39 - - - - - - - -
LHNGMDCD_01583 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LHNGMDCD_01584 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
LHNGMDCD_01585 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LHNGMDCD_01586 2.41e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LHNGMDCD_01587 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LHNGMDCD_01588 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LHNGMDCD_01589 8.23e-228 ykvI - - S - - - membrane
LHNGMDCD_01590 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LHNGMDCD_01591 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LHNGMDCD_01592 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LHNGMDCD_01593 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LHNGMDCD_01594 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LHNGMDCD_01595 5.87e-74 eag - - - - - - -
LHNGMDCD_01597 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
LHNGMDCD_01598 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LHNGMDCD_01599 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LHNGMDCD_01600 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LHNGMDCD_01601 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LHNGMDCD_01602 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHNGMDCD_01603 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LHNGMDCD_01604 7.07e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LHNGMDCD_01605 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LHNGMDCD_01607 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHNGMDCD_01608 3.34e-20 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_01609 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_01610 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LHNGMDCD_01611 4.83e-30 ykzE - - - - - - -
LHNGMDCD_01613 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LHNGMDCD_01614 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LHNGMDCD_01615 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
LHNGMDCD_01616 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LHNGMDCD_01617 3.83e-204 rsgI - - S - - - Anti-sigma factor N-terminus
LHNGMDCD_01618 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_01619 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LHNGMDCD_01620 1.71e-143 ykoX - - S - - - membrane-associated protein
LHNGMDCD_01621 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LHNGMDCD_01622 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LHNGMDCD_01623 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LHNGMDCD_01624 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LHNGMDCD_01625 0.0 ykoS - - - - - - -
LHNGMDCD_01626 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LHNGMDCD_01627 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
LHNGMDCD_01628 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LHNGMDCD_01629 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LHNGMDCD_01630 3.04e-36 ykoL - - - - - - -
LHNGMDCD_01631 1.63e-25 - - - - - - - -
LHNGMDCD_01632 1.49e-70 tnrA - - K - - - transcriptional
LHNGMDCD_01633 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LHNGMDCD_01635 1.45e-08 - - - - - - - -
LHNGMDCD_01636 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
LHNGMDCD_01637 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
LHNGMDCD_01638 6.05e-307 ykoH - - T - - - Histidine kinase
LHNGMDCD_01639 1.68e-156 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_01640 4.05e-141 ykoF - - S - - - YKOF-related Family
LHNGMDCD_01641 3.99e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LHNGMDCD_01642 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_01643 5.18e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LHNGMDCD_01644 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHNGMDCD_01645 6.07e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHNGMDCD_01646 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LHNGMDCD_01647 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
LHNGMDCD_01648 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
LHNGMDCD_01649 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
LHNGMDCD_01650 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LHNGMDCD_01651 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LHNGMDCD_01652 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHNGMDCD_01653 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LHNGMDCD_01654 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LHNGMDCD_01655 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LHNGMDCD_01656 6.97e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHNGMDCD_01657 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
LHNGMDCD_01658 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_01659 9.93e-15 - - - - - - - -
LHNGMDCD_01660 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHNGMDCD_01661 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
LHNGMDCD_01662 9.79e-102 ykgA - - E - - - Amidinotransferase
LHNGMDCD_01663 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LHNGMDCD_01664 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_01665 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LHNGMDCD_01666 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LHNGMDCD_01667 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LHNGMDCD_01669 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHNGMDCD_01670 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_01671 8.28e-222 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_01672 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHNGMDCD_01673 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LHNGMDCD_01674 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
LHNGMDCD_01675 8.69e-184 - - - - - - - -
LHNGMDCD_01676 7.04e-118 yocC - - - - - - -
LHNGMDCD_01677 1.41e-242 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LHNGMDCD_01678 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LHNGMDCD_01679 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_01680 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_01682 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
LHNGMDCD_01683 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHNGMDCD_01684 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHNGMDCD_01685 2.87e-107 yocK - - T - - - general stress protein
LHNGMDCD_01686 4.29e-70 yocL - - - - - - -
LHNGMDCD_01687 3.93e-41 - - - - - - - -
LHNGMDCD_01688 1.13e-92 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHNGMDCD_01689 2.94e-55 yozN - - - - - - -
LHNGMDCD_01690 1.83e-49 yocN - - - - - - -
LHNGMDCD_01691 2.17e-74 yozO - - S - - - Bacterial PH domain
LHNGMDCD_01692 1.91e-42 yozC - - - - - - -
LHNGMDCD_01693 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHNGMDCD_01694 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LHNGMDCD_01695 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LHNGMDCD_01696 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LHNGMDCD_01697 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
LHNGMDCD_01698 1.05e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LHNGMDCD_01699 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LHNGMDCD_01700 0.0 yojO - - P - - - Von Willebrand factor
LHNGMDCD_01701 7.38e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LHNGMDCD_01702 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LHNGMDCD_01703 2.48e-262 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHNGMDCD_01704 3.12e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LHNGMDCD_01705 2.14e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LHNGMDCD_01707 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LHNGMDCD_01708 2.91e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHNGMDCD_01709 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LHNGMDCD_01710 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
LHNGMDCD_01711 1.85e-58 - - - - - - - -
LHNGMDCD_01712 6.68e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LHNGMDCD_01713 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LHNGMDCD_01714 1.13e-13 - - - - - - - -
LHNGMDCD_01715 3.6e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LHNGMDCD_01716 5.64e-84 iolK - - S - - - tautomerase
LHNGMDCD_01717 2.63e-73 yodB - - K - - - transcriptional
LHNGMDCD_01718 1.92e-140 yodC - - C - - - nitroreductase
LHNGMDCD_01719 2.17e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LHNGMDCD_01720 5.61e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHNGMDCD_01721 3.36e-38 - - - S - - - Protein of unknown function (DUF3311)
LHNGMDCD_01722 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHNGMDCD_01723 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LHNGMDCD_01724 3.03e-166 yodH - - Q - - - Methyltransferase
LHNGMDCD_01725 2.81e-40 yodI - - - - - - -
LHNGMDCD_01726 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LHNGMDCD_01727 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LHNGMDCD_01728 2.08e-12 - - - - - - - -
LHNGMDCD_01729 1.17e-71 yodL - - S - - - YodL-like
LHNGMDCD_01730 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LHNGMDCD_01731 5.18e-34 yozD - - S - - - YozD-like protein
LHNGMDCD_01733 7.44e-159 yodN - - - - - - -
LHNGMDCD_01734 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
LHNGMDCD_01735 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
LHNGMDCD_01736 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LHNGMDCD_01737 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LHNGMDCD_01738 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LHNGMDCD_01739 3.66e-78 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LHNGMDCD_01740 1.15e-58 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LHNGMDCD_01742 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHNGMDCD_01744 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LHNGMDCD_01745 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LHNGMDCD_01746 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
LHNGMDCD_01747 3.62e-82 cgeA - - - ko:K06319 - ko00000 -
LHNGMDCD_01748 4.45e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LHNGMDCD_01749 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LHNGMDCD_01750 5.51e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LHNGMDCD_01751 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LHNGMDCD_01752 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LHNGMDCD_01753 4.14e-94 ypoP - - K - - - transcriptional
LHNGMDCD_01754 1.65e-288 mepA - - V - - - MATE efflux family protein
LHNGMDCD_01755 1.24e-39 ypmT - - S - - - Uncharacterized ympT
LHNGMDCD_01756 4.59e-127 ypmS - - S - - - protein conserved in bacteria
LHNGMDCD_01757 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LHNGMDCD_01758 1.24e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LHNGMDCD_01759 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
LHNGMDCD_01760 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LHNGMDCD_01761 5.47e-234 yplP - - K - - - Transcriptional regulator
LHNGMDCD_01762 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LHNGMDCD_01763 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LHNGMDCD_01764 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHNGMDCD_01765 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LHNGMDCD_01766 2.01e-147 ypjP - - S - - - YpjP-like protein
LHNGMDCD_01767 5.05e-186 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LHNGMDCD_01768 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
LHNGMDCD_01769 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LHNGMDCD_01770 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LHNGMDCD_01771 7.22e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LHNGMDCD_01772 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LHNGMDCD_01773 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHNGMDCD_01774 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LHNGMDCD_01775 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LHNGMDCD_01776 1.17e-22 degR - - - - - - -
LHNGMDCD_01777 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
LHNGMDCD_01778 1.54e-37 ypeQ - - S - - - Zinc-finger
LHNGMDCD_01779 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LHNGMDCD_01780 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LHNGMDCD_01781 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LHNGMDCD_01782 2.59e-05 - - - - ko:K06429 - ko00000 -
LHNGMDCD_01783 2.26e-213 ypcP - - L - - - 5'3' exonuclease
LHNGMDCD_01784 1.08e-11 - - - - - - - -
LHNGMDCD_01785 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
LHNGMDCD_01786 0.0 ypbR - - S - - - Dynamin family
LHNGMDCD_01787 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LHNGMDCD_01788 4.08e-41 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LHNGMDCD_01789 1.49e-201 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LHNGMDCD_01790 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LHNGMDCD_01791 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LHNGMDCD_01792 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LHNGMDCD_01793 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LHNGMDCD_01794 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LHNGMDCD_01795 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LHNGMDCD_01796 2.24e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
LHNGMDCD_01797 7.26e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LHNGMDCD_01798 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_01799 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LHNGMDCD_01801 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LHNGMDCD_01802 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LHNGMDCD_01803 1.39e-127 ypsA - - S - - - Belongs to the UPF0398 family
LHNGMDCD_01804 2.81e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LHNGMDCD_01805 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LHNGMDCD_01806 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LHNGMDCD_01807 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LHNGMDCD_01808 8.36e-66 yppG - - S - - - YppG-like protein
LHNGMDCD_01809 9.21e-11 - - - S - - - YppF-like protein
LHNGMDCD_01810 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
LHNGMDCD_01813 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
LHNGMDCD_01814 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LHNGMDCD_01815 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LHNGMDCD_01816 4.09e-121 ypoC - - - - - - -
LHNGMDCD_01817 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHNGMDCD_01818 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LHNGMDCD_01819 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LHNGMDCD_01820 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LHNGMDCD_01821 2.66e-102 ypmB - - S - - - protein conserved in bacteria
LHNGMDCD_01822 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LHNGMDCD_01823 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LHNGMDCD_01824 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LHNGMDCD_01825 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LHNGMDCD_01826 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LHNGMDCD_01827 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LHNGMDCD_01828 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LHNGMDCD_01829 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LHNGMDCD_01830 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LHNGMDCD_01831 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LHNGMDCD_01832 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LHNGMDCD_01833 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LHNGMDCD_01834 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHNGMDCD_01835 6.56e-181 ypjB - - S - - - sporulation protein
LHNGMDCD_01836 1.15e-125 ypjA - - S - - - membrane
LHNGMDCD_01837 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LHNGMDCD_01838 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LHNGMDCD_01839 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LHNGMDCD_01840 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
LHNGMDCD_01841 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
LHNGMDCD_01842 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
LHNGMDCD_01843 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LHNGMDCD_01844 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LHNGMDCD_01845 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LHNGMDCD_01846 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LHNGMDCD_01847 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LHNGMDCD_01848 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LHNGMDCD_01849 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LHNGMDCD_01850 2.37e-227 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LHNGMDCD_01851 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHNGMDCD_01852 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LHNGMDCD_01853 3.86e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LHNGMDCD_01854 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LHNGMDCD_01855 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LHNGMDCD_01856 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LHNGMDCD_01857 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LHNGMDCD_01858 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LHNGMDCD_01859 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LHNGMDCD_01860 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LHNGMDCD_01861 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LHNGMDCD_01863 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
LHNGMDCD_01864 5.46e-74 ygzB - - S - - - UPF0295 protein
LHNGMDCD_01865 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LHNGMDCD_01866 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LHNGMDCD_01867 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LHNGMDCD_01868 8.86e-237 ygaE - - S - - - Membrane
LHNGMDCD_01869 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LHNGMDCD_01870 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LHNGMDCD_01871 2.01e-49 ygaB - - S - - - YgaB-like protein
LHNGMDCD_01872 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LHNGMDCD_01873 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_01874 1.73e-48 yfhS - - - - - - -
LHNGMDCD_01875 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LHNGMDCD_01876 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LHNGMDCD_01877 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LHNGMDCD_01878 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHNGMDCD_01879 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
LHNGMDCD_01880 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
LHNGMDCD_01881 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
LHNGMDCD_01882 8.95e-60 yfhJ - - S - - - WVELL protein
LHNGMDCD_01883 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
LHNGMDCD_01884 2.45e-268 yfhI - - EGP - - - -transporter
LHNGMDCD_01886 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LHNGMDCD_01887 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LHNGMDCD_01888 2.56e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LHNGMDCD_01890 8.86e-35 yfhD - - S - - - YfhD-like protein
LHNGMDCD_01891 1.17e-137 yfhC - - C - - - nitroreductase
LHNGMDCD_01892 9.95e-211 yfhB - - S - - - PhzF family
LHNGMDCD_01893 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_01894 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_01895 1.28e-229 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LHNGMDCD_01896 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LHNGMDCD_01897 4.26e-103 yfiV - - K - - - transcriptional
LHNGMDCD_01898 7.8e-22 yfiU - - EGP - - - the major facilitator superfamily
LHNGMDCD_01899 1.11e-291 yfiU - - EGP - - - the major facilitator superfamily
LHNGMDCD_01900 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LHNGMDCD_01901 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
LHNGMDCD_01902 4.01e-139 yfiR - - K - - - Transcriptional regulator
LHNGMDCD_01903 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LHNGMDCD_01904 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LHNGMDCD_01905 1.89e-128 padR - - K - - - transcriptional
LHNGMDCD_01906 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LHNGMDCD_01907 5.69e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_01908 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_01909 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
LHNGMDCD_01910 1.7e-272 baeS - - T - - - Histidine kinase
LHNGMDCD_01912 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LHNGMDCD_01913 1.93e-82 yfiD3 - - S - - - DoxX
LHNGMDCD_01914 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHNGMDCD_01915 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LHNGMDCD_01916 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01917 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LHNGMDCD_01918 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LHNGMDCD_01919 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
LHNGMDCD_01920 1.94e-270 yfjB - - - - - - -
LHNGMDCD_01921 1.02e-184 yfjC - - - - - - -
LHNGMDCD_01922 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
LHNGMDCD_01923 1e-105 - - - S - - - Family of unknown function (DUF5381)
LHNGMDCD_01924 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
LHNGMDCD_01925 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LHNGMDCD_01926 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LHNGMDCD_01927 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LHNGMDCD_01928 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LHNGMDCD_01929 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LHNGMDCD_01930 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LHNGMDCD_01932 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
LHNGMDCD_01933 1.25e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHNGMDCD_01934 3.04e-59 - - - S - - - YfzA-like protein
LHNGMDCD_01935 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHNGMDCD_01936 3.92e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LHNGMDCD_01937 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LHNGMDCD_01938 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LHNGMDCD_01939 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LHNGMDCD_01940 3.26e-36 yfjT - - - - - - -
LHNGMDCD_01941 1.76e-283 yfkA - - S - - - YfkB-like domain
LHNGMDCD_01942 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
LHNGMDCD_01943 3.69e-189 yfkD - - S - - - YfkD-like protein
LHNGMDCD_01944 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LHNGMDCD_01945 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_01946 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LHNGMDCD_01947 1.03e-66 yfkI - - S - - - gas vesicle protein
LHNGMDCD_01948 5.89e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHNGMDCD_01949 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
LHNGMDCD_01950 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_01951 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LHNGMDCD_01952 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHNGMDCD_01953 6.16e-160 frp - - C - - - nitroreductase
LHNGMDCD_01954 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LHNGMDCD_01955 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHNGMDCD_01956 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01957 1.43e-41 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LHNGMDCD_01958 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LHNGMDCD_01959 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHNGMDCD_01960 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LHNGMDCD_01961 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LHNGMDCD_01962 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
LHNGMDCD_01963 6.9e-27 yflI - - - - - - -
LHNGMDCD_01964 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
LHNGMDCD_01965 3.42e-157 yflK - - S - - - protein conserved in bacteria
LHNGMDCD_01966 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LHNGMDCD_01967 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LHNGMDCD_01968 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHNGMDCD_01969 1.78e-87 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHNGMDCD_01970 5.7e-179 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHNGMDCD_01971 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LHNGMDCD_01972 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LHNGMDCD_01973 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHNGMDCD_01974 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LHNGMDCD_01975 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LHNGMDCD_01976 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
LHNGMDCD_01977 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
LHNGMDCD_01978 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LHNGMDCD_01979 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_01980 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_01981 1.15e-191 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LHNGMDCD_01982 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LHNGMDCD_01983 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LHNGMDCD_01984 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
LHNGMDCD_01985 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
LHNGMDCD_01986 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LHNGMDCD_01987 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_01988 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_01989 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_01990 4.15e-14 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_01991 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHNGMDCD_01992 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LHNGMDCD_01993 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LHNGMDCD_01994 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LHNGMDCD_01995 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LHNGMDCD_01996 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LHNGMDCD_01997 1.27e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
LHNGMDCD_01998 2e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LHNGMDCD_01999 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LHNGMDCD_02000 2.19e-153 yxaC - - M - - - effector of murein hydrolase
LHNGMDCD_02001 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LHNGMDCD_02002 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHNGMDCD_02003 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02004 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LHNGMDCD_02005 5.18e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
LHNGMDCD_02006 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LHNGMDCD_02007 1.35e-97 yxaI - - S - - - membrane protein domain
LHNGMDCD_02008 7.97e-83 - - - S - - - Family of unknown function (DUF5391)
LHNGMDCD_02009 2.54e-43 yxaI - - S - - - membrane protein domain
LHNGMDCD_02010 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHNGMDCD_02011 6.97e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LHNGMDCD_02012 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHNGMDCD_02013 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHNGMDCD_02015 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LHNGMDCD_02016 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_02017 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_02018 1.05e-101 - - - T - - - HPP family
LHNGMDCD_02019 2.23e-17 - - - S - - - CGNR zinc finger
LHNGMDCD_02021 7.27e-55 - - - - - - - -
LHNGMDCD_02022 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LHNGMDCD_02023 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHNGMDCD_02024 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHNGMDCD_02025 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LHNGMDCD_02026 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LHNGMDCD_02027 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LHNGMDCD_02028 4.99e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LHNGMDCD_02029 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LHNGMDCD_02030 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LHNGMDCD_02031 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LHNGMDCD_02032 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LHNGMDCD_02033 3.3e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LHNGMDCD_02034 9.37e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_02035 1.75e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02036 8.64e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02037 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LHNGMDCD_02038 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
LHNGMDCD_02039 1.55e-215 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_02040 9.65e-91 - - - - - - - -
LHNGMDCD_02041 7.57e-28 yxeD - - - - - - -
LHNGMDCD_02042 5.99e-41 yxeE - - - - - - -
LHNGMDCD_02045 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
LHNGMDCD_02046 4.03e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LHNGMDCD_02047 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHNGMDCD_02048 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_02049 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LHNGMDCD_02050 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHNGMDCD_02051 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02052 4.78e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LHNGMDCD_02053 0.0 yxeQ - - S - - - MmgE/PrpD family
LHNGMDCD_02054 2.99e-249 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
LHNGMDCD_02055 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
LHNGMDCD_02056 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LHNGMDCD_02057 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LHNGMDCD_02058 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHNGMDCD_02059 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LHNGMDCD_02060 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHNGMDCD_02061 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LHNGMDCD_02062 1.49e-308 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LHNGMDCD_02063 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
LHNGMDCD_02064 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LHNGMDCD_02065 0.0 - - - L - - - HKD family nuclease
LHNGMDCD_02066 1.03e-80 - - - L - - - HKD family nuclease
LHNGMDCD_02067 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
LHNGMDCD_02068 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
LHNGMDCD_02069 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LHNGMDCD_02070 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LHNGMDCD_02071 1.56e-53 - - - - - - - -
LHNGMDCD_02072 8.86e-317 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LHNGMDCD_02073 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
LHNGMDCD_02074 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
LHNGMDCD_02075 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_02076 5.69e-208 yxxF - - EG - - - EamA-like transporter family
LHNGMDCD_02077 0.0 wapA - - M - - - COG3209 Rhs family protein
LHNGMDCD_02078 3.29e-19 yxiJ - - S - - - YxiJ-like protein
LHNGMDCD_02079 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
LHNGMDCD_02080 1.27e-69 - - - - - - - -
LHNGMDCD_02082 5.06e-175 - - - - - - - -
LHNGMDCD_02083 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
LHNGMDCD_02084 7.13e-100 - - - - - - - -
LHNGMDCD_02085 4.48e-58 - - - - - - - -
LHNGMDCD_02086 4.67e-89 yxiG - - - - - - -
LHNGMDCD_02087 9.7e-68 yxxG - - - - - - -
LHNGMDCD_02088 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
LHNGMDCD_02091 3.42e-173 - - - - - - - -
LHNGMDCD_02092 8.21e-50 yxiI - - S - - - Protein of unknown function (DUF2716)
LHNGMDCD_02093 1.86e-40 - - - - - - - -
LHNGMDCD_02096 4.06e-58 yxiJ - - S - - - YxiJ-like protein
LHNGMDCD_02099 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHNGMDCD_02100 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LHNGMDCD_02101 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LHNGMDCD_02102 7.23e-141 - - - - - - - -
LHNGMDCD_02103 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHNGMDCD_02104 7.21e-183 bglS - - M - - - licheninase activity
LHNGMDCD_02105 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LHNGMDCD_02106 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHNGMDCD_02107 2.28e-63 yxiS - - - - - - -
LHNGMDCD_02108 1.51e-91 - - - T - - - Domain of unknown function (DUF4163)
LHNGMDCD_02109 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHNGMDCD_02110 9.07e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LHNGMDCD_02111 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LHNGMDCD_02112 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHNGMDCD_02113 1.69e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LHNGMDCD_02114 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LHNGMDCD_02115 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LHNGMDCD_02116 2.13e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LHNGMDCD_02117 2.88e-111 yxjI - - S - - - LURP-one-related
LHNGMDCD_02119 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LHNGMDCD_02120 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
LHNGMDCD_02121 8.24e-73 - - - T - - - Signal transduction histidine kinase
LHNGMDCD_02122 1.76e-166 - - - T - - - Signal transduction histidine kinase
LHNGMDCD_02123 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
LHNGMDCD_02124 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LHNGMDCD_02125 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
LHNGMDCD_02126 3.85e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LHNGMDCD_02127 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LHNGMDCD_02128 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LHNGMDCD_02129 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LHNGMDCD_02130 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LHNGMDCD_02131 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LHNGMDCD_02132 3.76e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHNGMDCD_02133 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LHNGMDCD_02134 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LHNGMDCD_02135 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LHNGMDCD_02136 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LHNGMDCD_02137 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LHNGMDCD_02138 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LHNGMDCD_02139 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LHNGMDCD_02140 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LHNGMDCD_02141 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LHNGMDCD_02142 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LHNGMDCD_02143 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LHNGMDCD_02144 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LHNGMDCD_02145 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LHNGMDCD_02146 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LHNGMDCD_02147 8.41e-202 yloC - - S - - - stress-induced protein
LHNGMDCD_02148 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LHNGMDCD_02149 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LHNGMDCD_02150 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LHNGMDCD_02151 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHNGMDCD_02152 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHNGMDCD_02153 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LHNGMDCD_02154 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LHNGMDCD_02155 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LHNGMDCD_02156 2.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LHNGMDCD_02157 1.38e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LHNGMDCD_02158 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LHNGMDCD_02159 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LHNGMDCD_02160 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LHNGMDCD_02161 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LHNGMDCD_02162 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LHNGMDCD_02163 3.65e-78 yloU - - S - - - protein conserved in bacteria
LHNGMDCD_02164 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LHNGMDCD_02165 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LHNGMDCD_02166 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LHNGMDCD_02167 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHNGMDCD_02168 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LHNGMDCD_02169 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LHNGMDCD_02170 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LHNGMDCD_02171 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LHNGMDCD_02172 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHNGMDCD_02173 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LHNGMDCD_02174 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LHNGMDCD_02175 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LHNGMDCD_02176 1.67e-114 - - - - - - - -
LHNGMDCD_02177 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LHNGMDCD_02178 1.13e-307 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHNGMDCD_02179 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LHNGMDCD_02180 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LHNGMDCD_02181 3.41e-80 ylqD - - S - - - YlqD protein
LHNGMDCD_02182 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHNGMDCD_02183 1.98e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LHNGMDCD_02184 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LHNGMDCD_02185 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LHNGMDCD_02186 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHNGMDCD_02187 0.0 ylqG - - - - - - -
LHNGMDCD_02188 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LHNGMDCD_02189 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LHNGMDCD_02190 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LHNGMDCD_02191 3.48e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LHNGMDCD_02192 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHNGMDCD_02193 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LHNGMDCD_02194 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LHNGMDCD_02195 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LHNGMDCD_02196 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LHNGMDCD_02197 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LHNGMDCD_02198 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LHNGMDCD_02199 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LHNGMDCD_02200 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LHNGMDCD_02201 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LHNGMDCD_02202 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LHNGMDCD_02203 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LHNGMDCD_02204 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LHNGMDCD_02205 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LHNGMDCD_02206 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
LHNGMDCD_02207 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LHNGMDCD_02208 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LHNGMDCD_02209 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LHNGMDCD_02210 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LHNGMDCD_02211 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LHNGMDCD_02212 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LHNGMDCD_02213 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LHNGMDCD_02214 3.99e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LHNGMDCD_02215 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LHNGMDCD_02216 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LHNGMDCD_02217 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LHNGMDCD_02218 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LHNGMDCD_02219 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LHNGMDCD_02220 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LHNGMDCD_02221 1.81e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LHNGMDCD_02222 1.49e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LHNGMDCD_02223 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LHNGMDCD_02224 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LHNGMDCD_02225 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LHNGMDCD_02226 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LHNGMDCD_02227 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_02228 6.91e-101 ylxL - - - - - - -
LHNGMDCD_02229 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LHNGMDCD_02230 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LHNGMDCD_02231 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LHNGMDCD_02232 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LHNGMDCD_02233 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHNGMDCD_02234 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LHNGMDCD_02235 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LHNGMDCD_02236 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LHNGMDCD_02237 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LHNGMDCD_02238 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHNGMDCD_02239 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LHNGMDCD_02240 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LHNGMDCD_02241 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LHNGMDCD_02242 6.16e-63 ylxQ - - J - - - ribosomal protein
LHNGMDCD_02243 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LHNGMDCD_02244 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LHNGMDCD_02245 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LHNGMDCD_02246 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHNGMDCD_02247 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LHNGMDCD_02248 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LHNGMDCD_02249 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LHNGMDCD_02250 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LHNGMDCD_02251 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
LHNGMDCD_02252 1.53e-56 ymxH - - S - - - YlmC YmxH family
LHNGMDCD_02253 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LHNGMDCD_02254 1.36e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LHNGMDCD_02255 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LHNGMDCD_02256 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHNGMDCD_02257 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHNGMDCD_02258 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LHNGMDCD_02259 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LHNGMDCD_02260 4.94e-44 - - - S - - - YlzJ-like protein
LHNGMDCD_02261 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHNGMDCD_02262 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_02263 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_02264 9.47e-299 albE - - S - - - Peptidase M16
LHNGMDCD_02265 2.37e-309 ymfH - - S - - - zinc protease
LHNGMDCD_02266 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LHNGMDCD_02267 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
LHNGMDCD_02268 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LHNGMDCD_02269 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LHNGMDCD_02270 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHNGMDCD_02271 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LHNGMDCD_02272 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LHNGMDCD_02273 1.82e-276 pbpX - - V - - - Beta-lactamase
LHNGMDCD_02274 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LHNGMDCD_02275 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LHNGMDCD_02276 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LHNGMDCD_02277 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LHNGMDCD_02278 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LHNGMDCD_02279 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LHNGMDCD_02280 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LHNGMDCD_02281 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
LHNGMDCD_02285 2.98e-53 - - - - - - - -
LHNGMDCD_02286 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LHNGMDCD_02287 5.9e-171 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHNGMDCD_02288 9.99e-59 - - - - - - - -
LHNGMDCD_02289 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
LHNGMDCD_02290 9.13e-135 ywqM - - K - - - Transcriptional regulator
LHNGMDCD_02291 4.46e-153 - - - E - - - amino acid
LHNGMDCD_02299 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LHNGMDCD_02300 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LHNGMDCD_02301 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LHNGMDCD_02302 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_02303 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LHNGMDCD_02304 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LHNGMDCD_02305 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LHNGMDCD_02306 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LHNGMDCD_02307 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LHNGMDCD_02308 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LHNGMDCD_02309 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LHNGMDCD_02310 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LHNGMDCD_02311 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHNGMDCD_02312 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LHNGMDCD_02313 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LHNGMDCD_02314 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LHNGMDCD_02315 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LHNGMDCD_02316 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LHNGMDCD_02317 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LHNGMDCD_02318 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LHNGMDCD_02319 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LHNGMDCD_02320 4.19e-75 ydbP - - CO - - - Thioredoxin
LHNGMDCD_02321 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHNGMDCD_02323 1.49e-26 - - - S - - - Fur-regulated basic protein B
LHNGMDCD_02324 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
LHNGMDCD_02325 9.32e-70 ydbL - - - - - - -
LHNGMDCD_02326 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHNGMDCD_02327 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02328 1.32e-230 ydbI - - S - - - AI-2E family transporter
LHNGMDCD_02329 7.33e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHNGMDCD_02330 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LHNGMDCD_02331 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHNGMDCD_02332 4.99e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LHNGMDCD_02333 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
LHNGMDCD_02334 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
LHNGMDCD_02335 2.17e-78 ydbB - - G - - - Cupin domain
LHNGMDCD_02336 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
LHNGMDCD_02337 4.3e-190 ydbA - - P - - - EcsC protein family
LHNGMDCD_02338 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LHNGMDCD_02339 1.67e-42 ydaS - - S - - - membrane
LHNGMDCD_02340 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LHNGMDCD_02341 6.14e-53 - - - - - - - -
LHNGMDCD_02343 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
LHNGMDCD_02344 3.67e-34 - - - - - - - -
LHNGMDCD_02345 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LHNGMDCD_02346 5.12e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LHNGMDCD_02347 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LHNGMDCD_02348 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LHNGMDCD_02349 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LHNGMDCD_02350 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LHNGMDCD_02351 6.13e-100 ydaG - - S - - - general stress protein
LHNGMDCD_02352 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHNGMDCD_02353 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LHNGMDCD_02354 1.52e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_02355 1e-127 ydaC - - Q - - - Methyltransferase domain
LHNGMDCD_02356 0.0 ydaB - - IQ - - - acyl-CoA ligase
LHNGMDCD_02357 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LHNGMDCD_02358 8.6e-220 ycsN - - S - - - Oxidoreductase
LHNGMDCD_02359 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LHNGMDCD_02360 8.97e-65 yczJ - - S - - - biosynthesis
LHNGMDCD_02362 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LHNGMDCD_02363 1.55e-170 kipR - - K - - - Transcriptional regulator
LHNGMDCD_02364 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LHNGMDCD_02365 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LHNGMDCD_02366 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LHNGMDCD_02367 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LHNGMDCD_02368 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LHNGMDCD_02369 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHNGMDCD_02370 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
LHNGMDCD_02371 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LHNGMDCD_02372 2.75e-136 ytqB - - J - - - Putative rRNA methylase
LHNGMDCD_02373 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LHNGMDCD_02374 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LHNGMDCD_02375 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LHNGMDCD_02376 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_02377 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHNGMDCD_02378 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LHNGMDCD_02379 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LHNGMDCD_02381 3.2e-265 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LHNGMDCD_02382 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LHNGMDCD_02383 6.01e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LHNGMDCD_02384 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_02385 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LHNGMDCD_02386 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LHNGMDCD_02387 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LHNGMDCD_02388 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LHNGMDCD_02389 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHNGMDCD_02390 4.54e-205 ytbE - - S - - - reductase
LHNGMDCD_02391 1.6e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LHNGMDCD_02392 1.15e-86 ytcD - - K - - - Transcriptional regulator
LHNGMDCD_02393 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LHNGMDCD_02394 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LHNGMDCD_02395 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LHNGMDCD_02396 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LHNGMDCD_02397 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LHNGMDCD_02398 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
LHNGMDCD_02399 2e-204 ytxC - - S - - - YtxC-like family
LHNGMDCD_02401 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LHNGMDCD_02402 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LHNGMDCD_02403 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02404 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LHNGMDCD_02405 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LHNGMDCD_02406 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LHNGMDCD_02408 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LHNGMDCD_02409 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LHNGMDCD_02410 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LHNGMDCD_02411 3.65e-59 ysdA - - S - - - Membrane
LHNGMDCD_02412 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
LHNGMDCD_02413 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
LHNGMDCD_02414 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LHNGMDCD_02415 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LHNGMDCD_02416 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LHNGMDCD_02417 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LHNGMDCD_02418 1.46e-87 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LHNGMDCD_02419 2.52e-61 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LHNGMDCD_02420 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LHNGMDCD_02421 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LHNGMDCD_02422 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LHNGMDCD_02423 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LHNGMDCD_02424 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LHNGMDCD_02425 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LHNGMDCD_02426 8.42e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
LHNGMDCD_02427 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LHNGMDCD_02428 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LHNGMDCD_02429 3.19e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LHNGMDCD_02430 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LHNGMDCD_02431 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHNGMDCD_02432 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LHNGMDCD_02433 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHNGMDCD_02434 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHNGMDCD_02435 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LHNGMDCD_02436 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
LHNGMDCD_02437 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LHNGMDCD_02438 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LHNGMDCD_02439 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
LHNGMDCD_02440 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LHNGMDCD_02441 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_02442 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LHNGMDCD_02443 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LHNGMDCD_02444 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LHNGMDCD_02446 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LHNGMDCD_02447 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LHNGMDCD_02448 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LHNGMDCD_02449 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHNGMDCD_02450 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
LHNGMDCD_02451 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LHNGMDCD_02452 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LHNGMDCD_02453 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LHNGMDCD_02454 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LHNGMDCD_02455 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_02456 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHNGMDCD_02457 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LHNGMDCD_02458 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LHNGMDCD_02459 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LHNGMDCD_02460 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LHNGMDCD_02461 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LHNGMDCD_02463 3.17e-170 - - - L - - - Phage integrase family
LHNGMDCD_02466 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LHNGMDCD_02467 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
LHNGMDCD_02468 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
LHNGMDCD_02469 3.84e-87 res - - L - - - Resolvase, N terminal domain
LHNGMDCD_02470 3.81e-275 ywfA - - EGP - - - -transporter
LHNGMDCD_02471 8.84e-317 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LHNGMDCD_02472 0.0 rocB - - E - - - arginine degradation protein
LHNGMDCD_02473 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LHNGMDCD_02474 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHNGMDCD_02475 3.7e-101 - - - - - - - -
LHNGMDCD_02476 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LHNGMDCD_02477 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LHNGMDCD_02478 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LHNGMDCD_02479 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LHNGMDCD_02480 4.71e-239 spsG - - M - - - Spore Coat
LHNGMDCD_02481 2.47e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
LHNGMDCD_02482 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LHNGMDCD_02483 2.01e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LHNGMDCD_02484 3.06e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LHNGMDCD_02485 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LHNGMDCD_02486 8.08e-187 spsA - - M - - - Spore Coat
LHNGMDCD_02487 3.7e-106 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LHNGMDCD_02488 1.59e-78 ywdK - - S - - - small membrane protein
LHNGMDCD_02489 1.86e-303 ywdJ - - F - - - Xanthine uracil
LHNGMDCD_02490 1.26e-62 ywdI - - S - - - Family of unknown function (DUF5327)
LHNGMDCD_02491 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHNGMDCD_02492 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LHNGMDCD_02493 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
LHNGMDCD_02494 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LHNGMDCD_02495 6.19e-39 ywdA - - - - - - -
LHNGMDCD_02496 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LHNGMDCD_02497 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_02498 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LHNGMDCD_02499 3.69e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHNGMDCD_02501 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHNGMDCD_02502 2.6e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHNGMDCD_02503 1.9e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LHNGMDCD_02504 2.19e-174 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LHNGMDCD_02506 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LHNGMDCD_02507 1.3e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LHNGMDCD_02508 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LHNGMDCD_02509 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LHNGMDCD_02510 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LHNGMDCD_02511 5.11e-49 ydaS - - S - - - membrane
LHNGMDCD_02512 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LHNGMDCD_02513 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LHNGMDCD_02514 3.33e-77 gtcA - - S - - - GtrA-like protein
LHNGMDCD_02515 1.98e-157 ywcC - - K - - - transcriptional regulator
LHNGMDCD_02517 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
LHNGMDCD_02518 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHNGMDCD_02519 1.47e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LHNGMDCD_02520 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LHNGMDCD_02521 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
LHNGMDCD_02522 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
LHNGMDCD_02523 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LHNGMDCD_02524 5.39e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LHNGMDCD_02525 1.28e-201 ywbI - - K - - - Transcriptional regulator
LHNGMDCD_02526 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LHNGMDCD_02527 1.21e-143 ywbG - - M - - - effector of murein hydrolase
LHNGMDCD_02528 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
LHNGMDCD_02529 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LHNGMDCD_02530 1.28e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LHNGMDCD_02531 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LHNGMDCD_02532 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
LHNGMDCD_02533 1.81e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHNGMDCD_02534 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHNGMDCD_02535 4.43e-307 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_02536 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LHNGMDCD_02537 5.37e-216 gspA - - M - - - General stress
LHNGMDCD_02538 3.49e-158 ywaF - - S - - - Integral membrane protein
LHNGMDCD_02539 1.25e-114 ywaE - - K - - - Transcriptional regulator
LHNGMDCD_02540 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHNGMDCD_02541 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LHNGMDCD_02542 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LHNGMDCD_02543 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHNGMDCD_02544 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHNGMDCD_02545 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02546 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LHNGMDCD_02547 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LHNGMDCD_02548 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_02550 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
LHNGMDCD_02552 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHNGMDCD_02553 1.87e-65 yqiX - - S - - - YolD-like protein
LHNGMDCD_02554 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LHNGMDCD_02555 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LHNGMDCD_02556 3.23e-248 yqkA - - K - - - GrpB protein
LHNGMDCD_02557 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
LHNGMDCD_02558 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
LHNGMDCD_02559 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LHNGMDCD_02560 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
LHNGMDCD_02561 2.09e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LHNGMDCD_02562 6.19e-09 - - - S - - - Protein of unknown function (DUF3936)
LHNGMDCD_02563 1.66e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LHNGMDCD_02564 3.71e-97 yqxK - - L - - - DNA helicase
LHNGMDCD_02565 8.26e-142 yqxK - - L - - - DNA helicase
LHNGMDCD_02566 3.18e-77 ansR - - K - - - Transcriptional regulator
LHNGMDCD_02567 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LHNGMDCD_02568 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LHNGMDCD_02569 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LHNGMDCD_02570 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LHNGMDCD_02571 1.47e-41 yqkK - - - - - - -
LHNGMDCD_02572 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LHNGMDCD_02573 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LHNGMDCD_02574 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
LHNGMDCD_02575 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LHNGMDCD_02576 3.77e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LHNGMDCD_02577 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LHNGMDCD_02578 8.27e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHNGMDCD_02579 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LHNGMDCD_02580 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LHNGMDCD_02581 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_02582 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LHNGMDCD_02583 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LHNGMDCD_02584 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LHNGMDCD_02585 8.55e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LHNGMDCD_02586 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LHNGMDCD_02587 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
LHNGMDCD_02588 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LHNGMDCD_02589 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LHNGMDCD_02590 3.12e-192 ypuA - - S - - - Secreted protein
LHNGMDCD_02591 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHNGMDCD_02592 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHNGMDCD_02596 1.89e-40 - - - - - - - -
LHNGMDCD_02597 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
LHNGMDCD_02601 5.24e-60 - - - - - - - -
LHNGMDCD_02602 1.1e-20 - - - S - - - SMI1 / KNR4 family
LHNGMDCD_02603 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
LHNGMDCD_02605 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LHNGMDCD_02606 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LHNGMDCD_02607 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHNGMDCD_02608 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
LHNGMDCD_02610 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
LHNGMDCD_02611 1.14e-197 yybE - - K - - - Transcriptional regulator
LHNGMDCD_02612 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LHNGMDCD_02613 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LHNGMDCD_02614 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
LHNGMDCD_02615 7.4e-168 - - - - - - - -
LHNGMDCD_02616 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
LHNGMDCD_02617 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
LHNGMDCD_02618 2.3e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LHNGMDCD_02619 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LHNGMDCD_02621 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LHNGMDCD_02622 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LHNGMDCD_02623 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LHNGMDCD_02624 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LHNGMDCD_02625 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LHNGMDCD_02626 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LHNGMDCD_02627 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LHNGMDCD_02628 7.73e-176 yqeM - - Q - - - Methyltransferase
LHNGMDCD_02629 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHNGMDCD_02630 3.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LHNGMDCD_02631 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LHNGMDCD_02632 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LHNGMDCD_02633 2.36e-22 - - - S - - - YqzM-like protein
LHNGMDCD_02634 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LHNGMDCD_02635 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LHNGMDCD_02636 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LHNGMDCD_02637 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LHNGMDCD_02638 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
LHNGMDCD_02639 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LHNGMDCD_02640 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LHNGMDCD_02641 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LHNGMDCD_02642 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LHNGMDCD_02643 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LHNGMDCD_02644 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LHNGMDCD_02645 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LHNGMDCD_02646 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LHNGMDCD_02647 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LHNGMDCD_02648 8.29e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LHNGMDCD_02649 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LHNGMDCD_02650 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LHNGMDCD_02651 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LHNGMDCD_02652 4.35e-192 yqfA - - S - - - UPF0365 protein
LHNGMDCD_02653 2.23e-56 yqfB - - - - - - -
LHNGMDCD_02654 2.07e-60 yqfC - - S - - - sporulation protein YqfC
LHNGMDCD_02655 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LHNGMDCD_02656 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LHNGMDCD_02658 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LHNGMDCD_02659 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LHNGMDCD_02660 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LHNGMDCD_02661 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LHNGMDCD_02662 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHNGMDCD_02663 5.29e-27 - - - S - - - YqzL-like protein
LHNGMDCD_02664 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LHNGMDCD_02665 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LHNGMDCD_02666 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LHNGMDCD_02667 3.29e-144 ccpN - - K - - - CBS domain
LHNGMDCD_02668 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LHNGMDCD_02669 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LHNGMDCD_02670 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LHNGMDCD_02671 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LHNGMDCD_02672 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LHNGMDCD_02673 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LHNGMDCD_02674 7.29e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHNGMDCD_02675 1.01e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LHNGMDCD_02676 1.05e-48 yqfQ - - S - - - YqfQ-like protein
LHNGMDCD_02677 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LHNGMDCD_02678 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LHNGMDCD_02679 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LHNGMDCD_02680 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHNGMDCD_02681 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LHNGMDCD_02682 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LHNGMDCD_02683 2.38e-80 yqfX - - S - - - membrane
LHNGMDCD_02684 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LHNGMDCD_02685 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
LHNGMDCD_02686 1.12e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
LHNGMDCD_02687 2.36e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LHNGMDCD_02688 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LHNGMDCD_02689 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LHNGMDCD_02690 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LHNGMDCD_02691 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LHNGMDCD_02692 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LHNGMDCD_02693 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LHNGMDCD_02694 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHNGMDCD_02695 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LHNGMDCD_02696 1.09e-93 yqzC - - S - - - YceG-like family
LHNGMDCD_02697 2.81e-67 yqzD - - - - - - -
LHNGMDCD_02699 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
LHNGMDCD_02700 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LHNGMDCD_02701 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHNGMDCD_02702 3.38e-14 yqgO - - - - - - -
LHNGMDCD_02703 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LHNGMDCD_02704 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
LHNGMDCD_02705 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LHNGMDCD_02706 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHNGMDCD_02707 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LHNGMDCD_02708 2.69e-256 yqgU - - - - - - -
LHNGMDCD_02709 7.34e-66 yqgV - - S - - - Thiamine-binding protein
LHNGMDCD_02710 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
LHNGMDCD_02711 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LHNGMDCD_02712 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LHNGMDCD_02713 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LHNGMDCD_02714 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
LHNGMDCD_02715 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LHNGMDCD_02716 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LHNGMDCD_02717 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LHNGMDCD_02718 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LHNGMDCD_02719 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LHNGMDCD_02720 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LHNGMDCD_02722 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHNGMDCD_02723 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_02724 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02725 3.06e-204 yuxN - - K - - - Transcriptional regulator
LHNGMDCD_02726 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LHNGMDCD_02727 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
LHNGMDCD_02728 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHNGMDCD_02729 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LHNGMDCD_02730 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LHNGMDCD_02731 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_02732 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02733 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LHNGMDCD_02734 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LHNGMDCD_02735 2.85e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LHNGMDCD_02736 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LHNGMDCD_02737 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_02738 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LHNGMDCD_02739 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LHNGMDCD_02740 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_02741 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LHNGMDCD_02742 2.89e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02743 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LHNGMDCD_02744 0.0 yvrG - - T - - - Histidine kinase
LHNGMDCD_02745 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_02746 5.07e-32 - - - - - - - -
LHNGMDCD_02747 1.12e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LHNGMDCD_02748 3.46e-26 - - - S - - - YvrJ protein family
LHNGMDCD_02749 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LHNGMDCD_02750 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
LHNGMDCD_02751 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHNGMDCD_02752 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02753 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
LHNGMDCD_02754 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHNGMDCD_02755 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_02756 4.04e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_02757 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_02759 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LHNGMDCD_02760 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LHNGMDCD_02761 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LHNGMDCD_02762 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LHNGMDCD_02765 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LHNGMDCD_02766 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LHNGMDCD_02767 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LHNGMDCD_02768 1.26e-20 yjlB - - S - - - Cupin domain
LHNGMDCD_02769 4.85e-54 yjlB - - S - - - Cupin domain
LHNGMDCD_02770 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LHNGMDCD_02771 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHNGMDCD_02772 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LHNGMDCD_02773 1.13e-165 - - - G ko:K03292 - ko00000 symporter YjmB
LHNGMDCD_02774 8.14e-128 - - - G ko:K03292 - ko00000 symporter YjmB
LHNGMDCD_02775 1.03e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
LHNGMDCD_02776 1.53e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LHNGMDCD_02777 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LHNGMDCD_02778 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02779 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
LHNGMDCD_02780 1.15e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LHNGMDCD_02781 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LHNGMDCD_02782 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LHNGMDCD_02783 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LHNGMDCD_02784 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LHNGMDCD_02785 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02786 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LHNGMDCD_02787 1.26e-18 - - - - - - - -
LHNGMDCD_02789 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
LHNGMDCD_02791 2.94e-17 - - - EGP - - - Major Facilitator
LHNGMDCD_02792 6.4e-09 - - - J - - - O-methyltransferase
LHNGMDCD_02793 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
LHNGMDCD_02794 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LHNGMDCD_02796 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LHNGMDCD_02797 3.48e-88 - - - S - - - YusW-like protein
LHNGMDCD_02798 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHNGMDCD_02799 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
LHNGMDCD_02800 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LHNGMDCD_02801 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_02802 4.86e-84 yusQ - - S - - - Tautomerase enzyme
LHNGMDCD_02803 0.0 yusP - - P - - - Major facilitator superfamily
LHNGMDCD_02804 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LHNGMDCD_02805 8.66e-70 yusN - - M - - - Coat F domain
LHNGMDCD_02806 2.23e-54 - - - - - - - -
LHNGMDCD_02807 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LHNGMDCD_02808 1.11e-13 - - - S - - - YuzL-like protein
LHNGMDCD_02809 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LHNGMDCD_02810 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LHNGMDCD_02811 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LHNGMDCD_02812 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LHNGMDCD_02813 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LHNGMDCD_02814 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
LHNGMDCD_02815 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LHNGMDCD_02816 8.14e-73 yusE - - CO - - - Thioredoxin
LHNGMDCD_02817 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
LHNGMDCD_02818 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHNGMDCD_02819 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LHNGMDCD_02820 1.96e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LHNGMDCD_02821 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHNGMDCD_02822 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LHNGMDCD_02823 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LHNGMDCD_02824 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHNGMDCD_02825 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LHNGMDCD_02826 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LHNGMDCD_02827 1.79e-149 - - - L - - - Belongs to the 'phage' integrase family
LHNGMDCD_02831 7.24e-60 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_02832 1.7e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_02833 4.59e-23 - - - - - - - -
LHNGMDCD_02835 2.79e-87 - - - L - - - dnaD_dom DnaD domain protein
LHNGMDCD_02836 2.01e-64 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA replication protein
LHNGMDCD_02838 1.88e-09 - - - - - - - -
LHNGMDCD_02844 3.09e-63 - - - S - - - dUTPase
LHNGMDCD_02850 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHNGMDCD_02851 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LHNGMDCD_02852 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
LHNGMDCD_02853 2.52e-196 yndG - - S - - - DoxX-like family
LHNGMDCD_02854 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
LHNGMDCD_02855 0.0 yndJ - - S - - - YndJ-like protein
LHNGMDCD_02858 6.31e-173 yndL - - S - - - Replication protein
LHNGMDCD_02859 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
LHNGMDCD_02860 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LHNGMDCD_02861 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHNGMDCD_02862 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LHNGMDCD_02863 5.4e-143 yneB - - L - - - resolvase
LHNGMDCD_02864 1.15e-43 ynzC - - S - - - UPF0291 protein
LHNGMDCD_02865 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LHNGMDCD_02866 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LHNGMDCD_02867 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LHNGMDCD_02868 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
LHNGMDCD_02869 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LHNGMDCD_02870 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LHNGMDCD_02871 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LHNGMDCD_02872 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
LHNGMDCD_02873 1.33e-160 ynaC - - - - - - -
LHNGMDCD_02874 8.25e-61 - - - S - - - Restriction endonuclease
LHNGMDCD_02875 7.12e-37 - - - - - - - -
LHNGMDCD_02876 1.14e-20 - - - S - - - peptidoglycan catabolic process
LHNGMDCD_02877 2.45e-34 - - - K - - - Helix-turn-helix domain
LHNGMDCD_02878 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHNGMDCD_02879 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LHNGMDCD_02880 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LHNGMDCD_02881 3.26e-72 - - - L - - - transposase activity
LHNGMDCD_02882 1.12e-134 yuaD - - - - - - -
LHNGMDCD_02883 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LHNGMDCD_02884 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LHNGMDCD_02885 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LHNGMDCD_02886 5.83e-118 yuaB - - - - - - -
LHNGMDCD_02887 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LHNGMDCD_02888 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
LHNGMDCD_02889 3.31e-52 yubF - - S - - - yiaA/B two helix domain
LHNGMDCD_02890 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LHNGMDCD_02891 0.0 yubD - - P - - - Major Facilitator Superfamily
LHNGMDCD_02892 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
LHNGMDCD_02894 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LHNGMDCD_02895 1.73e-252 yubA - - S - - - transporter activity
LHNGMDCD_02896 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHNGMDCD_02897 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LHNGMDCD_02898 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LHNGMDCD_02899 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LHNGMDCD_02900 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHNGMDCD_02901 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
LHNGMDCD_02902 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_02903 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_02904 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_02905 2.02e-284 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_02906 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LHNGMDCD_02907 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LHNGMDCD_02908 5e-48 - - - - - - - -
LHNGMDCD_02909 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LHNGMDCD_02910 7.23e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHNGMDCD_02911 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LHNGMDCD_02912 2.16e-48 - - - - - - - -
LHNGMDCD_02913 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
LHNGMDCD_02914 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LHNGMDCD_02915 2.75e-91 yugN - - S - - - YugN-like family
LHNGMDCD_02917 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LHNGMDCD_02918 1.2e-285 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LHNGMDCD_02919 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LHNGMDCD_02920 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LHNGMDCD_02921 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LHNGMDCD_02922 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LHNGMDCD_02923 6.74e-112 alaR - - K - - - Transcriptional regulator
LHNGMDCD_02924 9.89e-201 yugF - - I - - - Hydrolase
LHNGMDCD_02925 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
LHNGMDCD_02926 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LHNGMDCD_02927 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02928 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LHNGMDCD_02929 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LHNGMDCD_02931 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
LHNGMDCD_02932 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LHNGMDCD_02933 1.92e-97 yuxK - - S - - - protein conserved in bacteria
LHNGMDCD_02934 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
LHNGMDCD_02935 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LHNGMDCD_02936 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LHNGMDCD_02937 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LHNGMDCD_02938 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02939 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHNGMDCD_02940 1.15e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LHNGMDCD_02941 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
LHNGMDCD_02942 1.42e-21 - - - - - - - -
LHNGMDCD_02943 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LHNGMDCD_02944 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHNGMDCD_02945 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHNGMDCD_02946 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHNGMDCD_02947 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHNGMDCD_02948 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LHNGMDCD_02949 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LHNGMDCD_02950 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LHNGMDCD_02951 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_02952 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_02953 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHNGMDCD_02954 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHNGMDCD_02955 4.84e-85 - - - S - - - damaged DNA binding
LHNGMDCD_02956 2.34e-14 - - - S - - - YolD-like protein
LHNGMDCD_02959 1.06e-127 - - - J - - - Acetyltransferase (GNAT) domain
LHNGMDCD_02960 7.01e-129 yokK - - S - - - SMI1 / KNR4 family
LHNGMDCD_02961 3.18e-101 - - - S - - - SMI1-KNR4 cell-wall
LHNGMDCD_02962 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHNGMDCD_02963 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHNGMDCD_02964 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
LHNGMDCD_02965 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
LHNGMDCD_02966 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LHNGMDCD_02967 5.45e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LHNGMDCD_02968 2.81e-178 - - - J - - - FR47-like protein
LHNGMDCD_02969 6.23e-127 yobS - - K - - - Transcriptional regulator
LHNGMDCD_02970 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHNGMDCD_02971 4.8e-111 - - - K - - - Bacterial transcription activator, effector binding domain
LHNGMDCD_02972 1.73e-221 yobV - - K - - - WYL domain
LHNGMDCD_02973 7.38e-121 yobW - - - - - - -
LHNGMDCD_02974 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LHNGMDCD_02975 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LHNGMDCD_02977 2.29e-29 ywtC - - - - - - -
LHNGMDCD_02978 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LHNGMDCD_02979 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LHNGMDCD_02980 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LHNGMDCD_02982 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LHNGMDCD_02983 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02984 4.46e-211 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_02985 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LHNGMDCD_02986 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02987 3.99e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHNGMDCD_02988 2.23e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_02989 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LHNGMDCD_02990 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_02991 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LHNGMDCD_02992 5.71e-41 yttA - - S - - - Pfam Transposase IS66
LHNGMDCD_02993 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
LHNGMDCD_02994 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LHNGMDCD_02995 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
LHNGMDCD_02996 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LHNGMDCD_02997 1.22e-68 ytwF - - P - - - Sulfurtransferase
LHNGMDCD_02998 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LHNGMDCD_02999 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LHNGMDCD_03000 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LHNGMDCD_03001 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHNGMDCD_03002 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03003 4.8e-221 - - - S - - - Acetyl xylan esterase (AXE1)
LHNGMDCD_03004 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LHNGMDCD_03005 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LHNGMDCD_03006 4.1e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LHNGMDCD_03007 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LHNGMDCD_03008 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LHNGMDCD_03009 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHNGMDCD_03010 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
LHNGMDCD_03011 1.19e-190 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LHNGMDCD_03012 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LHNGMDCD_03013 1.13e-165 ytdP - - K - - - Transcriptional regulator
LHNGMDCD_03014 2.13e-75 ytdP - - K - - - Transcriptional regulator
LHNGMDCD_03015 1.36e-202 ytdP - - K - - - Transcriptional regulator
LHNGMDCD_03016 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LHNGMDCD_03017 8.3e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LHNGMDCD_03018 9.64e-94 yteS - - G - - - transport
LHNGMDCD_03019 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LHNGMDCD_03020 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LHNGMDCD_03021 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LHNGMDCD_03022 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LHNGMDCD_03023 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LHNGMDCD_03024 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHNGMDCD_03025 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LHNGMDCD_03026 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LHNGMDCD_03027 1.12e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LHNGMDCD_03028 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LHNGMDCD_03029 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LHNGMDCD_03030 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LHNGMDCD_03031 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LHNGMDCD_03032 9.92e-212 ytlQ - - - - - - -
LHNGMDCD_03033 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LHNGMDCD_03034 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LHNGMDCD_03035 3.02e-192 ytmP - - M - - - Phosphotransferase
LHNGMDCD_03036 9.51e-61 ytzH - - S - - - YtzH-like protein
LHNGMDCD_03037 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LHNGMDCD_03038 3.05e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LHNGMDCD_03039 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LHNGMDCD_03040 1.17e-67 ytzB - - S - - - small secreted protein
LHNGMDCD_03041 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LHNGMDCD_03042 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LHNGMDCD_03043 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LHNGMDCD_03044 3.17e-75 ytpP - - CO - - - Thioredoxin
LHNGMDCD_03045 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
LHNGMDCD_03046 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LHNGMDCD_03047 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LHNGMDCD_03048 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LHNGMDCD_03049 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LHNGMDCD_03050 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LHNGMDCD_03051 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
LHNGMDCD_03052 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LHNGMDCD_03053 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LHNGMDCD_03054 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LHNGMDCD_03055 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LHNGMDCD_03056 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LHNGMDCD_03057 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LHNGMDCD_03058 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LHNGMDCD_03059 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LHNGMDCD_03060 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHNGMDCD_03062 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LHNGMDCD_03063 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LHNGMDCD_03064 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LHNGMDCD_03065 9.83e-141 yttP - - K - - - Transcriptional regulator
LHNGMDCD_03066 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LHNGMDCD_03067 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LHNGMDCD_03068 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LHNGMDCD_03069 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LHNGMDCD_03070 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LHNGMDCD_03071 5.88e-38 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LHNGMDCD_03072 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LHNGMDCD_03073 0.0 ytcJ - - S - - - amidohydrolase
LHNGMDCD_03074 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LHNGMDCD_03075 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LHNGMDCD_03076 8.71e-176 yphF - - - - - - -
LHNGMDCD_03077 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
LHNGMDCD_03078 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LHNGMDCD_03079 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LHNGMDCD_03080 2.06e-38 ypzH - - - - - - -
LHNGMDCD_03081 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
LHNGMDCD_03082 1.11e-133 yphA - - - - - - -
LHNGMDCD_03083 1.13e-11 - - - S - - - YpzI-like protein
LHNGMDCD_03084 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LHNGMDCD_03085 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
LHNGMDCD_03086 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHNGMDCD_03088 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LHNGMDCD_03089 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LHNGMDCD_03090 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LHNGMDCD_03091 5.7e-41 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LHNGMDCD_03092 3.33e-247 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LHNGMDCD_03093 1.34e-74 - - - - - - - -
LHNGMDCD_03094 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LHNGMDCD_03095 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LHNGMDCD_03096 1.34e-132 ycnI - - S - - - protein conserved in bacteria
LHNGMDCD_03097 3.27e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_03098 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LHNGMDCD_03099 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHNGMDCD_03100 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHNGMDCD_03101 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_03102 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHNGMDCD_03103 1.68e-60 ycnE - - S - - - Monooxygenase
LHNGMDCD_03104 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHNGMDCD_03105 5.87e-198 ycnC - - K - - - Transcriptional regulator
LHNGMDCD_03106 0.0 ycnB - - EGP - - - the major facilitator superfamily
LHNGMDCD_03107 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LHNGMDCD_03108 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_03109 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_03110 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHNGMDCD_03111 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LHNGMDCD_03112 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LHNGMDCD_03114 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHNGMDCD_03115 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LHNGMDCD_03116 2.09e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_03117 5.23e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LHNGMDCD_03118 1.33e-152 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LHNGMDCD_03119 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LHNGMDCD_03120 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
LHNGMDCD_03121 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LHNGMDCD_03123 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
LHNGMDCD_03124 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHNGMDCD_03126 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LHNGMDCD_03127 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LHNGMDCD_03128 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LHNGMDCD_03129 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
LHNGMDCD_03130 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LHNGMDCD_03131 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
LHNGMDCD_03132 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LHNGMDCD_03133 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LHNGMDCD_03134 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LHNGMDCD_03135 1.15e-52 xhlB - - S - - - SPP1 phage holin
LHNGMDCD_03136 2.21e-51 xhlA - - S - - - Haemolysin XhlA
LHNGMDCD_03137 9.79e-195 xepA - - - - - - -
LHNGMDCD_03138 6.35e-31 xkdX - - - - - - -
LHNGMDCD_03139 2.7e-68 xkdW - - S - - - XkdW protein
LHNGMDCD_03140 0.0 - - - - - - - -
LHNGMDCD_03141 4.43e-56 - - - - - - - -
LHNGMDCD_03142 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LHNGMDCD_03143 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LHNGMDCD_03144 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
LHNGMDCD_03145 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
LHNGMDCD_03146 2.31e-232 xkdQ - - G - - - NLP P60 protein
LHNGMDCD_03147 1.73e-151 xkdP - - S - - - Lysin motif
LHNGMDCD_03148 0.0 xkdO - - L - - - Transglycosylase SLT domain
LHNGMDCD_03149 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LHNGMDCD_03150 2.45e-98 xkdM - - S - - - Phage tail tube protein
LHNGMDCD_03151 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LHNGMDCD_03152 2.87e-101 xkdJ - - - - - - -
LHNGMDCD_03153 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHNGMDCD_03154 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
LHNGMDCD_03155 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
LHNGMDCD_03156 3.91e-217 xkdG - - S - - - Phage capsid family
LHNGMDCD_03157 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
LHNGMDCD_03158 0.0 yqbA - - S - - - portal protein
LHNGMDCD_03159 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LHNGMDCD_03160 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LHNGMDCD_03161 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LHNGMDCD_03166 8.72e-152 xkdC - - L - - - Bacterial dnaA protein
LHNGMDCD_03167 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
LHNGMDCD_03169 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_03170 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
LHNGMDCD_03171 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
LHNGMDCD_03172 1.11e-138 yjqB - - S - - - Pfam:DUF867
LHNGMDCD_03173 1.35e-80 yjqA - - S - - - Bacterial PH domain
LHNGMDCD_03174 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHNGMDCD_03175 1.09e-34 - - - S - - - YCII-related domain
LHNGMDCD_03177 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_03178 0.0 yclG - - M - - - Pectate lyase superfamily protein
LHNGMDCD_03179 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LHNGMDCD_03180 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
LHNGMDCD_03181 6.45e-55 yclD - - - - - - -
LHNGMDCD_03182 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LHNGMDCD_03183 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LHNGMDCD_03184 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LHNGMDCD_03185 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LHNGMDCD_03186 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LHNGMDCD_03187 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LHNGMDCD_03188 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LHNGMDCD_03189 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
LHNGMDCD_03190 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LHNGMDCD_03191 0.0 ycxD - - K - - - GntR family transcriptional regulator
LHNGMDCD_03192 1.17e-198 ycxC - - EG - - - EamA-like transporter family
LHNGMDCD_03193 1.48e-122 - - - S - - - YcxB-like protein
LHNGMDCD_03194 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LHNGMDCD_03195 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LHNGMDCD_03196 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LHNGMDCD_03197 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LHNGMDCD_03198 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LHNGMDCD_03199 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LHNGMDCD_03200 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LHNGMDCD_03201 1.52e-79 ytkC - - S - - - Bacteriophage holin family
LHNGMDCD_03202 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LHNGMDCD_03204 4.78e-95 ytkA - - S - - - YtkA-like
LHNGMDCD_03205 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LHNGMDCD_03206 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LHNGMDCD_03207 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LHNGMDCD_03208 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LHNGMDCD_03209 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LHNGMDCD_03210 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LHNGMDCD_03211 7.92e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LHNGMDCD_03212 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LHNGMDCD_03213 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LHNGMDCD_03214 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LHNGMDCD_03215 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LHNGMDCD_03216 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LHNGMDCD_03217 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LHNGMDCD_03218 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LHNGMDCD_03219 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LHNGMDCD_03220 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LHNGMDCD_03221 1.44e-167 yteA - - T - - - COG1734 DnaK suppressor protein
LHNGMDCD_03222 5.69e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LHNGMDCD_03223 4.1e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LHNGMDCD_03224 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
LHNGMDCD_03225 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
LHNGMDCD_03227 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
LHNGMDCD_03228 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
LHNGMDCD_03229 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
LHNGMDCD_03230 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LHNGMDCD_03231 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LHNGMDCD_03232 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LHNGMDCD_03233 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
LHNGMDCD_03234 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LHNGMDCD_03235 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LHNGMDCD_03258 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
LHNGMDCD_03259 3.86e-10 - - - S - - - Family of unknown function (DUF5316)
LHNGMDCD_03260 8.21e-15 - - - K - - - Transcriptional regulator
LHNGMDCD_03261 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LHNGMDCD_03262 3.75e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHNGMDCD_03263 1.81e-41 yazB - - K - - - transcriptional
LHNGMDCD_03264 1.31e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LHNGMDCD_03265 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LHNGMDCD_03266 5.28e-202 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LHNGMDCD_03267 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LHNGMDCD_03268 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LHNGMDCD_03269 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHNGMDCD_03270 3.65e-81 ynaC - - - - - - -
LHNGMDCD_03271 9.3e-51 ynaC - - - - - - -
LHNGMDCD_03272 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
LHNGMDCD_03273 4.13e-51 - - - - - - - -
LHNGMDCD_03274 1.46e-105 - - - - - - - -
LHNGMDCD_03276 1.68e-13 - - - - - - - -
LHNGMDCD_03278 4.6e-309 - - - M - - - nucleic acid phosphodiester bond hydrolysis
LHNGMDCD_03279 1.68e-53 - - - - - - - -
LHNGMDCD_03280 3.69e-32 - - - - - - - -
LHNGMDCD_03281 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LHNGMDCD_03282 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LHNGMDCD_03283 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LHNGMDCD_03284 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHNGMDCD_03285 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LHNGMDCD_03286 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHNGMDCD_03287 2.24e-141 - - - - - - - -
LHNGMDCD_03288 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHNGMDCD_03289 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHNGMDCD_03290 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LHNGMDCD_03291 1.2e-30 ymzA - - - - - - -
LHNGMDCD_03292 1.63e-31 - - - - - - - -
LHNGMDCD_03293 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LHNGMDCD_03294 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LHNGMDCD_03295 5.41e-76 ymaF - - S - - - YmaF family
LHNGMDCD_03297 2.45e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LHNGMDCD_03298 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
LHNGMDCD_03299 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LHNGMDCD_03300 3.96e-163 ymaC - - S - - - Replication protein
LHNGMDCD_03302 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LHNGMDCD_03303 1.96e-209 - - - S - - - Metallo-beta-lactamase superfamily
LHNGMDCD_03304 8.03e-81 ymzB - - - - - - -
LHNGMDCD_03305 1.02e-134 pksA - - K - - - Transcriptional regulator
LHNGMDCD_03306 9.3e-126 ymcC - - S - - - Membrane
LHNGMDCD_03307 2.23e-90 - - - S - - - Regulatory protein YrvL
LHNGMDCD_03308 9.96e-22 - - - - - - - -
LHNGMDCD_03309 7.74e-301 - - - I - - - Pfam Lipase (class 3)
LHNGMDCD_03310 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
LHNGMDCD_03311 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LHNGMDCD_03312 1.94e-248 yetN - - S - - - Protein of unknown function (DUF3900)
LHNGMDCD_03313 5.94e-131 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
LHNGMDCD_03314 1.3e-38 yetM - - CH - - - FAD binding domain
LHNGMDCD_03315 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LHNGMDCD_03316 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
LHNGMDCD_03317 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHNGMDCD_03318 1.39e-44 - - - - - - - -
LHNGMDCD_03319 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_03320 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LHNGMDCD_03321 3.66e-157 yetF - - S - - - membrane
LHNGMDCD_03322 1.53e-184 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LHNGMDCD_03323 3.72e-107 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LHNGMDCD_03324 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHNGMDCD_03325 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LHNGMDCD_03326 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHNGMDCD_03327 0.0 yetA - - - - - - -
LHNGMDCD_03328 2.25e-127 yetA - - - - - - -
LHNGMDCD_03329 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
LHNGMDCD_03330 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHNGMDCD_03331 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LHNGMDCD_03332 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LHNGMDCD_03333 4.69e-144 - - - S - - - Protein of unknown function, DUF624
LHNGMDCD_03334 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
LHNGMDCD_03335 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
LHNGMDCD_03336 0.0 yesS - - K - - - Transcriptional regulator
LHNGMDCD_03337 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
LHNGMDCD_03338 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHNGMDCD_03339 3.57e-120 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHNGMDCD_03340 6.98e-77 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LHNGMDCD_03341 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LHNGMDCD_03342 1.32e-69 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LHNGMDCD_03343 7.1e-163 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LHNGMDCD_03344 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_03345 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
LHNGMDCD_03346 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
LHNGMDCD_03347 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LHNGMDCD_03348 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LHNGMDCD_03349 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LHNGMDCD_03350 1.13e-193 yesF - - GM - - - NAD(P)H-binding
LHNGMDCD_03351 1.94e-68 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
LHNGMDCD_03352 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03353 6.29e-42 - - - L - - - COG3666 Transposase and inactivated derivatives
LHNGMDCD_03356 1.81e-37 bhlA - - S - - - BhlA holin family
LHNGMDCD_03357 3.19e-41 xhlB - - S - - - SPP1 phage holin
LHNGMDCD_03358 7.81e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LHNGMDCD_03359 8.88e-87 - - - S - - - Immunity protein 70
LHNGMDCD_03360 6.57e-233 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LHNGMDCD_03362 7.52e-55 - - - S - - - protein domain associated with
LHNGMDCD_03364 6.75e-38 - - - K - - - Helix-turn-helix domain
LHNGMDCD_03366 5.85e-35 - - - U - - - Preprotein translocase subunit SecB
LHNGMDCD_03370 1.17e-148 - - - - - - - -
LHNGMDCD_03371 5.53e-175 - - - - - - - -
LHNGMDCD_03372 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LHNGMDCD_03373 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LHNGMDCD_03374 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LHNGMDCD_03375 4.95e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LHNGMDCD_03376 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LHNGMDCD_03377 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHNGMDCD_03378 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LHNGMDCD_03379 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LHNGMDCD_03380 4.11e-183 - - - S - - - Ion transport 2 domain protein
LHNGMDCD_03381 1.91e-33 - - - S - - - Ion transport 2 domain protein
LHNGMDCD_03382 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_03385 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LHNGMDCD_03386 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LHNGMDCD_03387 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LHNGMDCD_03388 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LHNGMDCD_03389 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LHNGMDCD_03391 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LHNGMDCD_03392 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LHNGMDCD_03393 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LHNGMDCD_03394 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LHNGMDCD_03395 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LHNGMDCD_03396 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LHNGMDCD_03397 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LHNGMDCD_03398 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LHNGMDCD_03399 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LHNGMDCD_03400 1.91e-182 - - - L - - - Belongs to the 'phage' integrase family
LHNGMDCD_03401 2.71e-61 xkdA - - E - - - IrrE N-terminal-like domain
LHNGMDCD_03402 6.71e-28 - - - K - - - transcriptional
LHNGMDCD_03403 1.5e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
LHNGMDCD_03404 1.68e-48 - - - - - - - -
LHNGMDCD_03405 1.22e-48 - - - S - - - DNA binding
LHNGMDCD_03406 3.14e-110 - - - - - - - -
LHNGMDCD_03411 8.41e-125 - - - - - - - -
LHNGMDCD_03412 1.8e-87 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
LHNGMDCD_03414 4.69e-96 yqaL - - L - - - DnaD domain protein
LHNGMDCD_03415 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
LHNGMDCD_03417 2.02e-81 rusA - - L - - - Endodeoxyribonuclease RusA
LHNGMDCD_03418 1.78e-34 yqaO - - S - - - Phage-like element PBSX protein XtrA
LHNGMDCD_03421 1.19e-37 - - - - - - - -
LHNGMDCD_03422 6e-147 - - - - - - - -
LHNGMDCD_03424 1.84e-105 - - - L - - - Transposase
LHNGMDCD_03425 7.11e-39 - - - - - - - -
LHNGMDCD_03426 1.19e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
LHNGMDCD_03427 5.19e-102 - - - L - - - phage terminase small subunit
LHNGMDCD_03428 0.0 - - - S - - - Terminase
LHNGMDCD_03430 2.64e-303 - - - S - - - Phage portal protein
LHNGMDCD_03431 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
LHNGMDCD_03432 1.06e-266 - - - S - - - capsid protein
LHNGMDCD_03433 1.89e-34 - - - - - - - -
LHNGMDCD_03434 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
LHNGMDCD_03435 5.23e-52 - - - S - - - Phage head-tail joining protein
LHNGMDCD_03436 8.4e-67 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHNGMDCD_03438 1.67e-101 - - - N - - - Phage major tail protein phi13
LHNGMDCD_03439 1.77e-05 - - - - - - - -
LHNGMDCD_03441 0.0 - - - D - - - phage tail tape measure protein
LHNGMDCD_03442 1.19e-135 - - - S - - - Phage tail protein
LHNGMDCD_03443 1.92e-275 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LHNGMDCD_03444 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LHNGMDCD_03445 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LHNGMDCD_03446 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LHNGMDCD_03447 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
LHNGMDCD_03448 2.02e-138 ypfA - - M - - - Flagellar protein YcgR
LHNGMDCD_03449 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LHNGMDCD_03450 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LHNGMDCD_03451 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LHNGMDCD_03452 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LHNGMDCD_03453 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LHNGMDCD_03454 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LHNGMDCD_03455 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LHNGMDCD_03456 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
LHNGMDCD_03457 5.04e-148 ypbE - - M - - - Lysin motif
LHNGMDCD_03458 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LHNGMDCD_03459 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LHNGMDCD_03460 3.14e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LHNGMDCD_03461 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LHNGMDCD_03462 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LHNGMDCD_03463 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LHNGMDCD_03464 9.27e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LHNGMDCD_03465 2.96e-135 rsiX - - - - - - -
LHNGMDCD_03466 8.11e-17 rsiX - - - - - - -
LHNGMDCD_03467 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_03468 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_03469 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LHNGMDCD_03470 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LHNGMDCD_03471 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LHNGMDCD_03472 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LHNGMDCD_03473 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LHNGMDCD_03474 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LHNGMDCD_03475 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LHNGMDCD_03476 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHNGMDCD_03477 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
LHNGMDCD_03478 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHNGMDCD_03479 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHNGMDCD_03480 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LHNGMDCD_03481 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LHNGMDCD_03482 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LHNGMDCD_03483 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LHNGMDCD_03484 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LHNGMDCD_03485 3.42e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LHNGMDCD_03486 5.98e-72 ypuD - - - - - - -
LHNGMDCD_03487 1.54e-121 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHNGMDCD_03489 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
LHNGMDCD_03491 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHNGMDCD_03493 3.82e-37 - - - - - - - -
LHNGMDCD_03494 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
LHNGMDCD_03496 8.16e-77 - - - O - - - Papain family cysteine protease
LHNGMDCD_03497 1.73e-13 - - - - - - - -
LHNGMDCD_03498 5.89e-230 yaaC - - S - - - YaaC-like Protein
LHNGMDCD_03499 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LHNGMDCD_03500 3e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LHNGMDCD_03501 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LHNGMDCD_03502 5.55e-137 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LHNGMDCD_03503 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LHNGMDCD_03505 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LHNGMDCD_03506 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LHNGMDCD_03507 7.55e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LHNGMDCD_03508 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LHNGMDCD_03509 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LHNGMDCD_03510 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHNGMDCD_03511 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LHNGMDCD_03512 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHNGMDCD_03513 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
LHNGMDCD_03514 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LHNGMDCD_03516 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LHNGMDCD_03517 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LHNGMDCD_03518 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LHNGMDCD_03519 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LHNGMDCD_03520 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LHNGMDCD_03521 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
LHNGMDCD_03522 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_03523 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LHNGMDCD_03524 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LHNGMDCD_03525 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LHNGMDCD_03526 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_03527 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LHNGMDCD_03528 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LHNGMDCD_03529 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LHNGMDCD_03530 2.96e-292 yukF - - QT - - - Transcriptional regulator
LHNGMDCD_03531 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
LHNGMDCD_03532 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LHNGMDCD_03533 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LHNGMDCD_03534 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LHNGMDCD_03535 0.0 yueB - - S - - - type VII secretion protein EsaA
LHNGMDCD_03536 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
LHNGMDCD_03537 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_03538 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LHNGMDCD_03539 1.19e-32 - - - S - - - Protein of unknown function (DUF2642)
LHNGMDCD_03540 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
LHNGMDCD_03541 1.35e-244 yueF - - S - - - transporter activity
LHNGMDCD_03542 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LHNGMDCD_03543 1.63e-52 yueH - - S - - - YueH-like protein
LHNGMDCD_03544 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
LHNGMDCD_03545 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LHNGMDCD_03546 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LHNGMDCD_03547 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LHNGMDCD_03548 8.73e-09 yuzC - - - - - - -
LHNGMDCD_03550 6.29e-10 - - - S - - - DegQ (SacQ) family
LHNGMDCD_03551 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LHNGMDCD_03553 1.32e-97 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_03554 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LHNGMDCD_03555 1.96e-141 - - - S - - - Phage tail protein
LHNGMDCD_03556 0.0 - - - S - - - peptidoglycan catabolic process
LHNGMDCD_03557 4.09e-16 - - - - - - - -
LHNGMDCD_03558 1.58e-36 - - - - - - - -
LHNGMDCD_03559 9.75e-79 - - - - - - - -
LHNGMDCD_03560 1.42e-40 - - - - - - - -
LHNGMDCD_03561 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHNGMDCD_03562 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
LHNGMDCD_03563 1.23e-39 - - - S - - - peptidoglycan catabolic process
LHNGMDCD_03564 8.02e-09 - - - S - - - peptidoglycan catabolic process
LHNGMDCD_03565 3.43e-227 - - - S - - - capsid protein
LHNGMDCD_03566 9.36e-135 - - - S - - - peptidase activity
LHNGMDCD_03567 4.77e-273 - - - S - - - Phage portal protein
LHNGMDCD_03568 2.58e-14 - - - - - - - -
LHNGMDCD_03569 1.6e-276 - - - S - - - Phage Terminase
LHNGMDCD_03570 1e-89 - - - S - - - Phage terminase, small subunit
LHNGMDCD_03571 2.63e-11 - - - - - - - -
LHNGMDCD_03572 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LHNGMDCD_03573 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LHNGMDCD_03574 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
LHNGMDCD_03575 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LHNGMDCD_03576 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LHNGMDCD_03577 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LHNGMDCD_03578 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHNGMDCD_03579 8.92e-44 ylaI - - S - - - protein conserved in bacteria
LHNGMDCD_03580 4.4e-63 ylaH - - S - - - YlaH-like protein
LHNGMDCD_03581 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LHNGMDCD_03582 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
LHNGMDCD_03583 7.03e-57 ylaE - - - - - - -
LHNGMDCD_03585 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_03586 1.44e-56 ylaB - - - - - - -
LHNGMDCD_03587 0.0 ylaA - - - - - - -
LHNGMDCD_03588 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LHNGMDCD_03589 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LHNGMDCD_03590 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
LHNGMDCD_03591 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LHNGMDCD_03592 4.48e-35 ykzI - - - - - - -
LHNGMDCD_03593 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
LHNGMDCD_03594 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
LHNGMDCD_03595 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LHNGMDCD_03597 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
LHNGMDCD_03598 1.58e-36 - - - - - - - -
LHNGMDCD_03599 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LHNGMDCD_03600 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LHNGMDCD_03602 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHNGMDCD_03603 7.4e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LHNGMDCD_03604 2.79e-213 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LHNGMDCD_03605 4.62e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LHNGMDCD_03606 8.96e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LHNGMDCD_03609 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LHNGMDCD_03610 6.32e-99 ygaO - - - - - - -
LHNGMDCD_03611 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03613 1.07e-144 yhzB - - S - - - B3/4 domain
LHNGMDCD_03614 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LHNGMDCD_03615 9.27e-224 yhbB - - S - - - Putative amidase domain
LHNGMDCD_03616 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LHNGMDCD_03617 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
LHNGMDCD_03618 1.53e-94 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LHNGMDCD_03619 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LHNGMDCD_03620 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LHNGMDCD_03621 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LHNGMDCD_03622 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LHNGMDCD_03623 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LHNGMDCD_03624 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LHNGMDCD_03625 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
LHNGMDCD_03626 3.95e-59 yhcC - - - - - - -
LHNGMDCD_03627 2.06e-69 - - - - - - - -
LHNGMDCD_03628 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03629 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_03630 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_03631 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHNGMDCD_03632 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LHNGMDCD_03633 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LHNGMDCD_03634 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LHNGMDCD_03635 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LHNGMDCD_03636 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LHNGMDCD_03637 1.5e-81 - - - S - - - Immunity protein 70
LHNGMDCD_03641 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
LHNGMDCD_03643 4.39e-37 yddA - - - - - - -
LHNGMDCD_03647 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
LHNGMDCD_03648 9.78e-54 yddC - - - - - - -
LHNGMDCD_03649 6.91e-118 yddD - - S - - - TcpE family
LHNGMDCD_03650 1.59e-270 yddE - - S - - - AAA-like domain
LHNGMDCD_03651 2.21e-242 yddE - - S - - - AAA-like domain
LHNGMDCD_03652 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
LHNGMDCD_03653 0.0 yddG - - S - - - maturation of SSU-rRNA
LHNGMDCD_03654 1.03e-237 yddH - - M - - - Lysozyme-like
LHNGMDCD_03655 3.19e-111 yddI - - - - - - -
LHNGMDCD_03656 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
LHNGMDCD_03657 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
LHNGMDCD_03658 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_03660 9.39e-63 yhcM - - - - - - -
LHNGMDCD_03661 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LHNGMDCD_03662 3.38e-216 yhcP - - - - - - -
LHNGMDCD_03663 7.05e-124 yhcQ - - M - - - Spore coat protein
LHNGMDCD_03664 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LHNGMDCD_03665 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LHNGMDCD_03666 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LHNGMDCD_03667 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
LHNGMDCD_03668 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
LHNGMDCD_03669 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
LHNGMDCD_03670 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LHNGMDCD_03671 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHNGMDCD_03672 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LHNGMDCD_03673 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LHNGMDCD_03674 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LHNGMDCD_03675 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LHNGMDCD_03676 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LHNGMDCD_03677 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_03678 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_03679 1.9e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LHNGMDCD_03680 1.65e-51 yhdB - - S - - - YhdB-like protein
LHNGMDCD_03681 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
LHNGMDCD_03682 1.32e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LHNGMDCD_03683 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LHNGMDCD_03685 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LHNGMDCD_03686 1.82e-275 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LHNGMDCD_03687 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LHNGMDCD_03688 5.77e-267 acdA - - I - - - acyl-CoA dehydrogenase
LHNGMDCD_03689 3.8e-79 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LHNGMDCD_03690 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LHNGMDCD_03692 1.73e-70 - - - K - - - Helix-turn-helix
LHNGMDCD_03693 2.11e-49 - - - S - - - TM2 domain
LHNGMDCD_03694 2.62e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LHNGMDCD_03695 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LHNGMDCD_03698 8.51e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LHNGMDCD_03699 4.88e-147 lin0465 - - S - - - DJ-1/PfpI family
LHNGMDCD_03700 1.89e-100 yoaW - - - - - - -
LHNGMDCD_03701 3.7e-201 yoaV - - EG - - - EamA-like transporter family
LHNGMDCD_03702 1.35e-202 yoaU - - K - - - LysR substrate binding domain
LHNGMDCD_03703 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
LHNGMDCD_03704 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03705 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
LHNGMDCD_03706 5.78e-215 yoaR - - V - - - vancomycin resistance protein
LHNGMDCD_03707 3.94e-83 - - - - - - - -
LHNGMDCD_03710 3.1e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LHNGMDCD_03712 2.28e-67 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LHNGMDCD_03713 3.08e-122 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
LHNGMDCD_03714 1.79e-66 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
LHNGMDCD_03715 1.79e-145 yoaK - - S - - - Membrane
LHNGMDCD_03716 3.56e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
LHNGMDCD_03717 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LHNGMDCD_03718 1.88e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
LHNGMDCD_03719 5.32e-60 - - - L - - - Transposase and inactivated derivatives, TnpA family
LHNGMDCD_03720 2.89e-25 - - - L - - - Transposase and inactivated derivatives, TnpA family
LHNGMDCD_03721 2.2e-100 - - - - - - - -
LHNGMDCD_03722 5.09e-42 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LHNGMDCD_03723 5.92e-194 - - - EG - - - Spore germination protein
LHNGMDCD_03724 2.28e-13 - - - S - - - TIGRFAM germination protein, Ger(x)C family
LHNGMDCD_03725 2.56e-34 - - - S - - - Protein of unknown function (DUF2642)
LHNGMDCD_03726 7.51e-205 - - - P - - - Catalase
LHNGMDCD_03728 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
LHNGMDCD_03729 5.84e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LHNGMDCD_03730 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LHNGMDCD_03731 4.34e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
LHNGMDCD_03732 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
LHNGMDCD_03733 9.73e-194 - - - S - - - membrane
LHNGMDCD_03734 1.38e-16 - - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_03735 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_03736 0.0 - - - I - - - PLD-like domain
LHNGMDCD_03737 7.71e-128 - - - S - - - Protein of unknown function (DUF421)
LHNGMDCD_03738 2.23e-112 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LHNGMDCD_03739 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
LHNGMDCD_03740 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHNGMDCD_03741 6.07e-178 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LHNGMDCD_03742 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_03743 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LHNGMDCD_03744 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHNGMDCD_03745 7.05e-172 yoxB - - - - - - -
LHNGMDCD_03746 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
LHNGMDCD_03747 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_03748 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LHNGMDCD_03749 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHNGMDCD_03750 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LHNGMDCD_03751 2.05e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LHNGMDCD_03752 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03753 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LHNGMDCD_03754 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LHNGMDCD_03755 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LHNGMDCD_03756 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_03757 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LHNGMDCD_03758 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
LHNGMDCD_03759 1.14e-124 - - - L - - - Integrase
LHNGMDCD_03761 8.34e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LHNGMDCD_03762 1.14e-311 yoeA - - V - - - MATE efflux family protein
LHNGMDCD_03763 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LHNGMDCD_03764 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LHNGMDCD_03765 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_03766 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LHNGMDCD_03767 7.8e-49 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LHNGMDCD_03768 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
LHNGMDCD_03769 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LHNGMDCD_03770 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LHNGMDCD_03771 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LHNGMDCD_03772 5.62e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LHNGMDCD_03773 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LHNGMDCD_03774 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LHNGMDCD_03775 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LHNGMDCD_03776 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LHNGMDCD_03777 1.52e-163 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LHNGMDCD_03778 1.06e-98 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LHNGMDCD_03779 1.16e-133 yngC - - S - - - membrane-associated protein
LHNGMDCD_03780 1.07e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LHNGMDCD_03781 1.36e-100 yngA - - S - - - membrane
LHNGMDCD_03782 8.44e-31 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LHNGMDCD_03783 5.7e-309 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LHNGMDCD_03784 1.89e-31 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LHNGMDCD_03785 4.5e-242 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LHNGMDCD_03787 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LHNGMDCD_03788 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LHNGMDCD_03789 8.74e-75 ynfC - - - - - - -
LHNGMDCD_03790 1.82e-18 - - - - - - - -
LHNGMDCD_03791 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHNGMDCD_03792 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LHNGMDCD_03793 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LHNGMDCD_03794 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LHNGMDCD_03795 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
LHNGMDCD_03796 3.3e-71 yneQ - - - - - - -
LHNGMDCD_03797 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LHNGMDCD_03798 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LHNGMDCD_03800 9.26e-10 - - - S - - - Fur-regulated basic protein B
LHNGMDCD_03801 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LHNGMDCD_03802 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LHNGMDCD_03803 2.18e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LHNGMDCD_03804 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LHNGMDCD_03805 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
LHNGMDCD_03806 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
LHNGMDCD_03807 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LHNGMDCD_03809 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHNGMDCD_03810 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
LHNGMDCD_03811 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
LHNGMDCD_03812 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LHNGMDCD_03814 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LHNGMDCD_03815 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
LHNGMDCD_03816 1.13e-29 yjfB - - S - - - Putative motility protein
LHNGMDCD_03817 1.93e-62 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LHNGMDCD_03818 3.15e-136 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LHNGMDCD_03819 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
LHNGMDCD_03820 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
LHNGMDCD_03821 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LHNGMDCD_03822 5.25e-113 yjgD - - S - - - Protein of unknown function (DUF1641)
LHNGMDCD_03824 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LHNGMDCD_03826 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LHNGMDCD_03827 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LHNGMDCD_03828 1.11e-41 - - - - - - - -
LHNGMDCD_03829 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LHNGMDCD_03830 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LHNGMDCD_03831 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LHNGMDCD_03832 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LHNGMDCD_03833 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHNGMDCD_03834 5.14e-161 yfmS - - NT - - - chemotaxis protein
LHNGMDCD_03835 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHNGMDCD_03836 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
LHNGMDCD_03837 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LHNGMDCD_03838 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_03839 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LHNGMDCD_03840 6.7e-284 yfnE - - S - - - Glycosyltransferase like family 2
LHNGMDCD_03841 2.69e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LHNGMDCD_03842 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LHNGMDCD_03843 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LHNGMDCD_03844 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LHNGMDCD_03846 0.0 - - - - - - - -
LHNGMDCD_03847 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LHNGMDCD_03849 0.0 - - - D - - - Phage tail tape measure protein
LHNGMDCD_03852 1.46e-33 - - - - - - - -
LHNGMDCD_03854 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LHNGMDCD_03855 8.17e-38 - - - S - - - Phage head-tail joining protein
LHNGMDCD_03857 5.45e-13 - - - - - - - -
LHNGMDCD_03858 7.58e-162 - - - S - - - capsid protein
LHNGMDCD_03859 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
LHNGMDCD_03860 1.33e-216 - - - S - - - portal protein
LHNGMDCD_03862 1.19e-179 terL - - S - - - Terminase
LHNGMDCD_03863 3.93e-73 - - - L - - - Terminase, small subunit
LHNGMDCD_03869 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LHNGMDCD_03870 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LHNGMDCD_03871 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_03873 1.15e-20 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHNGMDCD_03874 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHNGMDCD_03875 4.04e-149 ydfE - - S - - - Flavin reductase like domain
LHNGMDCD_03876 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
LHNGMDCD_03877 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_03878 3.89e-194 - - - EG - - - EamA-like transporter family
LHNGMDCD_03879 8.66e-186 - - - J - - - GNAT acetyltransferase
LHNGMDCD_03880 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LHNGMDCD_03881 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LHNGMDCD_03882 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHNGMDCD_03883 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
LHNGMDCD_03884 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
LHNGMDCD_03885 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LHNGMDCD_03886 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_03887 4.66e-197 ydeK - - EG - - - -transporter
LHNGMDCD_03888 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
LHNGMDCD_03889 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
LHNGMDCD_03890 2.4e-41 - - - S - - - SNARE associated Golgi protein
LHNGMDCD_03891 4.95e-140 - - - - - - - -
LHNGMDCD_03892 4.72e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LHNGMDCD_03893 1.34e-196 ydeG - - EGP - - - Major facilitator superfamily
LHNGMDCD_03894 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_03895 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LHNGMDCD_03896 2.27e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LHNGMDCD_03897 2.44e-210 - - - K - - - AraC-like ligand binding domain
LHNGMDCD_03898 1.8e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LHNGMDCD_03900 2e-169 - - - - - - - -
LHNGMDCD_03901 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
LHNGMDCD_03902 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LHNGMDCD_03903 1.79e-84 ydjM - - M - - - Lytic transglycolase
LHNGMDCD_03904 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LHNGMDCD_03907 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
LHNGMDCD_03908 1.46e-201 - - - I - - - Alpha/beta hydrolase family
LHNGMDCD_03909 6.33e-103 yeaA - - S - - - Protein of unknown function (DUF4003)
LHNGMDCD_03910 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LHNGMDCD_03911 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LHNGMDCD_03912 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LHNGMDCD_03913 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LHNGMDCD_03914 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LHNGMDCD_03915 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LHNGMDCD_03916 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LHNGMDCD_03917 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_03918 1.15e-314 - - - S - - - Domain of unknown function (DUF4179)
LHNGMDCD_03919 6.6e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LHNGMDCD_03920 5.85e-165 yebC - - M - - - Membrane
LHNGMDCD_03921 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LHNGMDCD_03922 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LHNGMDCD_03923 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LHNGMDCD_03924 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LHNGMDCD_03925 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
LHNGMDCD_03926 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LHNGMDCD_03927 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LHNGMDCD_03928 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LHNGMDCD_03929 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LHNGMDCD_03930 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
LHNGMDCD_03931 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
LHNGMDCD_03932 2.84e-36 yqzE - - S - - - YqzE-like protein
LHNGMDCD_03933 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LHNGMDCD_03934 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LHNGMDCD_03935 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LHNGMDCD_03936 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
LHNGMDCD_03937 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LHNGMDCD_03938 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LHNGMDCD_03939 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LHNGMDCD_03940 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
LHNGMDCD_03941 8.73e-233 yqxL - - P - - - Mg2 transporter protein
LHNGMDCD_03942 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHNGMDCD_03943 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LHNGMDCD_03945 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LHNGMDCD_03946 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LHNGMDCD_03948 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_03949 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
LHNGMDCD_03950 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LHNGMDCD_03951 3.44e-142 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LHNGMDCD_03952 1.01e-310 yisQ - - V - - - Mate efflux family protein
LHNGMDCD_03953 1.41e-207 yisR - - K - - - Transcriptional regulator
LHNGMDCD_03954 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LHNGMDCD_03955 5.32e-242 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LHNGMDCD_03956 9.94e-120 yisT - - S - - - DinB family
LHNGMDCD_03957 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
LHNGMDCD_03958 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LHNGMDCD_03959 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
LHNGMDCD_03960 1.52e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LHNGMDCD_03961 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
LHNGMDCD_03962 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
LHNGMDCD_03963 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LHNGMDCD_03964 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LHNGMDCD_03965 3.91e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LHNGMDCD_03966 2.41e-121 - - - - - - - -
LHNGMDCD_03967 1.42e-218 - - - - - - - -
LHNGMDCD_03968 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
LHNGMDCD_03969 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
LHNGMDCD_03970 2.9e-118 - - - - - - - -
LHNGMDCD_03971 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
LHNGMDCD_03972 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LHNGMDCD_03973 4.16e-198 yitS - - S - - - protein conserved in bacteria
LHNGMDCD_03974 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LHNGMDCD_03975 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
LHNGMDCD_03976 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
LHNGMDCD_03977 1.92e-08 - - - - - - - -
LHNGMDCD_03978 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LHNGMDCD_03979 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LHNGMDCD_03980 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LHNGMDCD_03981 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
LHNGMDCD_03982 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LHNGMDCD_03983 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
LHNGMDCD_03984 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
LHNGMDCD_03985 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LHNGMDCD_03986 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LHNGMDCD_03987 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LHNGMDCD_03988 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LHNGMDCD_03989 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LHNGMDCD_03990 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LHNGMDCD_03991 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LHNGMDCD_03997 1.12e-33 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_03998 1.08e-60 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_03999 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LHNGMDCD_04000 2.43e-58 yjcN - - - - - - -
LHNGMDCD_04001 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LHNGMDCD_04002 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_04003 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LHNGMDCD_04004 3.33e-72 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LHNGMDCD_04006 2.66e-120 yebE - - S - - - UPF0316 protein
LHNGMDCD_04007 3.13e-38 yebG - - S - - - NETI protein
LHNGMDCD_04008 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LHNGMDCD_04009 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHNGMDCD_04010 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHNGMDCD_04011 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LHNGMDCD_04012 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHNGMDCD_04013 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHNGMDCD_04014 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHNGMDCD_04015 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LHNGMDCD_04016 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LHNGMDCD_04017 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHNGMDCD_04018 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LHNGMDCD_04019 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LHNGMDCD_04020 7.5e-92 - - - K - - - helix_turn_helix ASNC type
LHNGMDCD_04021 1.49e-240 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
LHNGMDCD_04022 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
LHNGMDCD_04023 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LHNGMDCD_04024 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LHNGMDCD_04025 6.27e-67 yerC - - S - - - protein conserved in bacteria
LHNGMDCD_04026 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LHNGMDCD_04028 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LHNGMDCD_04029 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LHNGMDCD_04030 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LHNGMDCD_04031 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LHNGMDCD_04032 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LHNGMDCD_04033 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LHNGMDCD_04034 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHNGMDCD_04035 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHNGMDCD_04036 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LHNGMDCD_04037 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHNGMDCD_04038 2.08e-190 yerO - - K - - - Transcriptional regulator
LHNGMDCD_04039 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LHNGMDCD_04040 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LHNGMDCD_04041 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LHNGMDCD_04042 0.0 - - - L - - - Type III restriction enzyme res subunit
LHNGMDCD_04046 1.59e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_04048 5.1e-36 - - - - - - - -
LHNGMDCD_04049 3.39e-98 - - - S - - - Protein of unknown function, DUF600
LHNGMDCD_04050 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LHNGMDCD_04052 2.44e-127 - - - L - - - endonuclease activity
LHNGMDCD_04053 1.23e-14 - - - S - - - Pfam:DUF1311
LHNGMDCD_04054 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LHNGMDCD_04056 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
LHNGMDCD_04060 0.0 - - - V - - - Beta-lactamase
LHNGMDCD_04062 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHNGMDCD_04064 4.82e-69 ynaF - - - - - - -
LHNGMDCD_04065 4.58e-133 - - - S - - - Domain of unknown function (DUF3885)
LHNGMDCD_04066 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LHNGMDCD_04067 4.98e-106 yoaW - - - - - - -
LHNGMDCD_04068 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHNGMDCD_04069 7.66e-99 - - - - - - - -
LHNGMDCD_04070 3.2e-59 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LHNGMDCD_04071 4.46e-23 - - - - - - - -
LHNGMDCD_04073 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LHNGMDCD_04075 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LHNGMDCD_04076 0.000751 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LHNGMDCD_04077 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
LHNGMDCD_04078 2.14e-17 - - - Q - - - methyltransferase
LHNGMDCD_04080 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LHNGMDCD_04081 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LHNGMDCD_04082 3.77e-97 - - - S - - - Bacterial PH domain
LHNGMDCD_04083 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LHNGMDCD_04084 8.33e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LHNGMDCD_04085 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LHNGMDCD_04086 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LHNGMDCD_04087 4.32e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LHNGMDCD_04088 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LHNGMDCD_04089 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LHNGMDCD_04090 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LHNGMDCD_04091 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LHNGMDCD_04092 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LHNGMDCD_04093 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LHNGMDCD_04094 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
LHNGMDCD_04095 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHNGMDCD_04096 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LHNGMDCD_04113 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LHNGMDCD_04114 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LHNGMDCD_04115 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LHNGMDCD_04116 1.05e-22 - - - - - - - -
LHNGMDCD_04117 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LHNGMDCD_04118 3.71e-110 ykyB - - S - - - YkyB-like protein
LHNGMDCD_04119 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_04120 5.84e-115 ykuD - - S - - - protein conserved in bacteria
LHNGMDCD_04121 1.42e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LHNGMDCD_04122 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_04123 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
LHNGMDCD_04124 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
LHNGMDCD_04125 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
LHNGMDCD_04126 7.83e-38 ykzF - - S - - - Antirepressor AbbA
LHNGMDCD_04127 6.01e-99 ykuL - - S - - - CBS domain
LHNGMDCD_04128 7.61e-215 ccpC - - K - - - Transcriptional regulator
LHNGMDCD_04129 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
LHNGMDCD_04130 1.74e-222 ykuO - - - - - - -
LHNGMDCD_04131 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
LHNGMDCD_04132 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LHNGMDCD_04133 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LHNGMDCD_04134 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
LHNGMDCD_04135 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LHNGMDCD_04136 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
LHNGMDCD_04137 4.23e-104 ykuV - - CO - - - thiol-disulfide
LHNGMDCD_04138 4.71e-122 rok - - K - - - Repressor of ComK
LHNGMDCD_04145 6.35e-53 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LHNGMDCD_04146 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LHNGMDCD_04147 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHNGMDCD_04148 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LHNGMDCD_04149 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LHNGMDCD_04150 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
LHNGMDCD_04151 1.63e-39 - - - - - - - -
LHNGMDCD_04152 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
LHNGMDCD_04153 3.33e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_04154 1.14e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LHNGMDCD_04155 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
LHNGMDCD_04156 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LHNGMDCD_04157 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LHNGMDCD_04158 1.05e-26 yxzF - - - - - - -
LHNGMDCD_04159 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LHNGMDCD_04160 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LHNGMDCD_04161 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LHNGMDCD_04162 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LHNGMDCD_04163 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LHNGMDCD_04164 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LHNGMDCD_04165 3.56e-43 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_04166 2.19e-07 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_04167 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_04168 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LHNGMDCD_04169 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_04170 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LHNGMDCD_04171 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LHNGMDCD_04173 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LHNGMDCD_04174 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LHNGMDCD_04175 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LHNGMDCD_04176 5.98e-100 - - - K - - - acetyltransferase
LHNGMDCD_04177 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LHNGMDCD_04178 9.64e-308 yhfN - - O - - - Peptidase M48
LHNGMDCD_04179 7.65e-83 yhfM - - - - - - -
LHNGMDCD_04181 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LHNGMDCD_04182 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LHNGMDCD_04183 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LHNGMDCD_04184 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LHNGMDCD_04185 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
LHNGMDCD_04187 0.0 - - - O - - - Peptidase family M48
LHNGMDCD_04188 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
LHNGMDCD_04189 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LHNGMDCD_04190 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LHNGMDCD_04191 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHNGMDCD_04192 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LHNGMDCD_04193 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LHNGMDCD_04194 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LHNGMDCD_04195 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LHNGMDCD_04196 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LHNGMDCD_04197 1.36e-123 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
LHNGMDCD_04198 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LHNGMDCD_04200 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LHNGMDCD_04201 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LHNGMDCD_04202 1.97e-46 yuiB - - S - - - Putative membrane protein
LHNGMDCD_04203 2.69e-148 yuiC - - S - - - protein conserved in bacteria
LHNGMDCD_04204 1.14e-217 - - - L - - - Replication protein
LHNGMDCD_04207 1.35e-64 XK26_06135 - - D - - - plasmid recombination enzyme
LHNGMDCD_04208 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHNGMDCD_04209 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LHNGMDCD_04211 2.51e-13 - - - - - - - -
LHNGMDCD_04212 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LHNGMDCD_04213 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LHNGMDCD_04214 1.79e-74 - - - S - - - Bacteriophage holin family
LHNGMDCD_04217 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LHNGMDCD_04218 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
LHNGMDCD_04219 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LHNGMDCD_04220 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LHNGMDCD_04221 2.92e-88 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHNGMDCD_04222 7.68e-25 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHNGMDCD_04223 0.0 - - - S - - - Fusaric acid resistance protein-like
LHNGMDCD_04224 1.94e-95 yvaD - - S - - - Family of unknown function (DUF5360)
LHNGMDCD_04225 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LHNGMDCD_04226 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
LHNGMDCD_04227 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LHNGMDCD_04231 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LHNGMDCD_04235 1.45e-38 - - - - - - - -
LHNGMDCD_04237 1.93e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LHNGMDCD_04238 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LHNGMDCD_04239 5.43e-52 ykoA - - - - - - -
LHNGMDCD_04240 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHNGMDCD_04241 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LHNGMDCD_04242 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LHNGMDCD_04243 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LHNGMDCD_04244 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LHNGMDCD_04245 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LHNGMDCD_04246 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHNGMDCD_04247 1.31e-150 yknW - - S - - - Yip1 domain
LHNGMDCD_04248 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHNGMDCD_04249 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LHNGMDCD_04250 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LHNGMDCD_04251 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LHNGMDCD_04252 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LHNGMDCD_04253 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LHNGMDCD_04254 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LHNGMDCD_04255 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LHNGMDCD_04256 9.46e-198 yknT - - - ko:K06437 - ko00000 -
LHNGMDCD_04257 7.55e-59 orfX1 - - L - - - Transposase
LHNGMDCD_04258 5.6e-173 - - - L - - - Integrase core domain
LHNGMDCD_04259 3.25e-137 - - - L - - - DNA ligase (ATP) activity
LHNGMDCD_04261 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
LHNGMDCD_04262 1.36e-267 - - - EGP - - - Transmembrane secretion effector
LHNGMDCD_04263 5.04e-259 yhjN - - S ko:K07120 - ko00000 membrane
LHNGMDCD_04264 5.09e-238 yhjM - - K - - - Transcriptional regulator
LHNGMDCD_04265 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LHNGMDCD_04266 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
LHNGMDCD_04267 9.38e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LHNGMDCD_04268 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LHNGMDCD_04271 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LHNGMDCD_04272 0.0 yhjG - - CH - - - FAD binding domain
LHNGMDCD_04273 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LHNGMDCD_04274 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
LHNGMDCD_04275 4.13e-78 yhjD - - - - - - -
LHNGMDCD_04276 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
LHNGMDCD_04277 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHNGMDCD_04278 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
LHNGMDCD_04279 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LHNGMDCD_04280 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LHNGMDCD_04281 9.84e-45 yhzC - - S - - - IDEAL
LHNGMDCD_04282 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LHNGMDCD_04283 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LHNGMDCD_04284 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LHNGMDCD_04285 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LHNGMDCD_04286 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LHNGMDCD_04287 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LHNGMDCD_04288 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LHNGMDCD_04289 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LHNGMDCD_04290 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LHNGMDCD_04291 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
LHNGMDCD_04292 6.98e-279 - - - L - - - Transposase
LHNGMDCD_04293 4.78e-152 - - - L - - - Bacterial dnaA protein
LHNGMDCD_04294 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LHNGMDCD_04297 7.54e-22 - - - - - - - -
LHNGMDCD_04298 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LHNGMDCD_04300 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHNGMDCD_04301 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LHNGMDCD_04302 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LHNGMDCD_04303 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LHNGMDCD_04304 5.71e-121 - - - M - - - FR47-like protein
LHNGMDCD_04305 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LHNGMDCD_04306 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LHNGMDCD_04307 6.53e-108 yuaE - - S - - - DinB superfamily
LHNGMDCD_04308 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LHNGMDCD_04309 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LHNGMDCD_04310 1.4e-203 - - - K - - - Transcriptional regulator
LHNGMDCD_04311 4.05e-43 yrdR - - EG - - - EamA-like transporter family
LHNGMDCD_04312 8.19e-157 yrdR - - EG - - - EamA-like transporter family
LHNGMDCD_04313 2.45e-23 - - - S - - - YrzO-like protein
LHNGMDCD_04314 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LHNGMDCD_04315 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LHNGMDCD_04316 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LHNGMDCD_04320 9.33e-108 - - - S - - - Protein of unknown function (DUF3800)
LHNGMDCD_04321 2.61e-15 - - - S - - - Protein of unknown function (DUF1433)
LHNGMDCD_04322 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
LHNGMDCD_04324 3.24e-93 - - - S - - - CAAX protease self-immunity
LHNGMDCD_04325 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LHNGMDCD_04326 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LHNGMDCD_04327 4.84e-09 - - - S - - - Domain of unknown function (DUF3885)
LHNGMDCD_04328 1.9e-102 - - - S - - - Domain of unknown function (DUF3885)
LHNGMDCD_04329 4.19e-20 ynaF - - - - - - -
LHNGMDCD_04331 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
LHNGMDCD_04332 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LHNGMDCD_04333 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LHNGMDCD_04334 6.82e-273 xylR - - GK - - - ROK family
LHNGMDCD_04335 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LHNGMDCD_04336 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LHNGMDCD_04338 5.08e-26 xkdM - - S - - - Phage tail tube protein
LHNGMDCD_04339 2.43e-14 - - - - - - - -
LHNGMDCD_04342 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
LHNGMDCD_04345 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
LHNGMDCD_04346 1.08e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LHNGMDCD_04347 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LHNGMDCD_04349 8.92e-96 - - - - - - - -
LHNGMDCD_04350 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
LHNGMDCD_04353 2.43e-162 - - - S - - - Domain of unknown function, YrpD
LHNGMDCD_04355 2.71e-103 yjoA - - S - - - DinB family
LHNGMDCD_04356 2.47e-268 VCP - - O - - - AAA domain (dynein-related subfamily)
LHNGMDCD_04357 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)