ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HGDKEKEP_00001 2.09e-103 - - - - - - - -
HGDKEKEP_00002 7.6e-12 - - - S - - - Helix-turn-helix domain
HGDKEKEP_00003 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_00004 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_00005 5.33e-85 - - - - - - - -
HGDKEKEP_00006 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
HGDKEKEP_00008 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
HGDKEKEP_00009 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
HGDKEKEP_00010 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
HGDKEKEP_00012 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
HGDKEKEP_00013 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HGDKEKEP_00014 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGDKEKEP_00015 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGDKEKEP_00016 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HGDKEKEP_00017 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HGDKEKEP_00018 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_00019 6.31e-51 - - - - - - - -
HGDKEKEP_00020 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGDKEKEP_00021 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
HGDKEKEP_00024 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HGDKEKEP_00026 1.51e-18 cotW - - - ko:K06341 - ko00000 -
HGDKEKEP_00027 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HGDKEKEP_00028 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HGDKEKEP_00029 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HGDKEKEP_00030 2.09e-103 yjbX - - S - - - Spore coat protein
HGDKEKEP_00031 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HGDKEKEP_00032 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HGDKEKEP_00033 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGDKEKEP_00034 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HGDKEKEP_00035 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HGDKEKEP_00036 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HGDKEKEP_00037 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HGDKEKEP_00038 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGDKEKEP_00039 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGDKEKEP_00040 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HGDKEKEP_00041 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HGDKEKEP_00042 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGDKEKEP_00043 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HGDKEKEP_00044 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
HGDKEKEP_00045 7.02e-128 yjbK - - S - - - protein conserved in bacteria
HGDKEKEP_00046 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGDKEKEP_00047 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HGDKEKEP_00048 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HGDKEKEP_00049 2.68e-28 - - - - - - - -
HGDKEKEP_00050 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HGDKEKEP_00051 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
HGDKEKEP_00052 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGDKEKEP_00053 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
HGDKEKEP_00054 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGDKEKEP_00055 1.41e-63 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_00056 2.77e-54 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_00057 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
HGDKEKEP_00058 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_00059 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_00060 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_00061 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_00062 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGDKEKEP_00063 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HGDKEKEP_00064 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HGDKEKEP_00065 5.34e-227 yyaD - - S - - - Membrane
HGDKEKEP_00066 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HGDKEKEP_00067 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGDKEKEP_00068 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGDKEKEP_00069 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HGDKEKEP_00070 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGDKEKEP_00071 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGDKEKEP_00072 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HGDKEKEP_00073 2.65e-60 ccpB - - K - - - Transcriptional regulator
HGDKEKEP_00074 2.14e-154 ccpB - - K - - - Transcriptional regulator
HGDKEKEP_00075 4.69e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_00076 3.01e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HGDKEKEP_00077 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HGDKEKEP_00078 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HGDKEKEP_00079 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HGDKEKEP_00080 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
HGDKEKEP_00081 1.67e-134 yyaP - - H - - - RibD C-terminal domain
HGDKEKEP_00082 2.28e-48 - - - S - - - YjbR
HGDKEKEP_00083 3.81e-87 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HGDKEKEP_00084 1.55e-125 yyaS - - S ko:K07149 - ko00000 Membrane
HGDKEKEP_00085 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
HGDKEKEP_00086 4.54e-100 yybA - - K - - - transcriptional
HGDKEKEP_00087 4.41e-105 - - - S - - - Metallo-beta-lactamase superfamily
HGDKEKEP_00088 3.87e-132 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_00089 6.02e-157 yybG - - S - - - Pentapeptide repeat-containing protein
HGDKEKEP_00090 5.02e-87 - - - S - - - SnoaL-like domain
HGDKEKEP_00091 2.05e-183 - - - - - - - -
HGDKEKEP_00092 7.24e-141 - - - K - - - TipAS antibiotic-recognition domain
HGDKEKEP_00093 7.94e-200 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_00094 5.21e-70 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_00096 3.19e-90 - - - - - - - -
HGDKEKEP_00097 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HGDKEKEP_00098 1.3e-87 yybR - - K - - - Transcriptional regulator
HGDKEKEP_00099 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
HGDKEKEP_00100 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
HGDKEKEP_00102 4.15e-120 yybS - - S - - - membrane
HGDKEKEP_00103 1.14e-34 yybS - - S - - - membrane
HGDKEKEP_00104 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HGDKEKEP_00105 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HGDKEKEP_00106 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGDKEKEP_00107 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HGDKEKEP_00108 1.89e-22 yycC - - K - - - YycC-like protein
HGDKEKEP_00110 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HGDKEKEP_00111 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HGDKEKEP_00112 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_00113 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGDKEKEP_00118 2.07e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_00119 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_00120 0.0 yycH - - S - - - protein conserved in bacteria
HGDKEKEP_00121 3.44e-200 yycI - - S - - - protein conserved in bacteria
HGDKEKEP_00122 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HGDKEKEP_00123 2.32e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGDKEKEP_00124 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HGDKEKEP_00125 2.31e-54 sdpR - - K - - - transcriptional
HGDKEKEP_00126 3.8e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HGDKEKEP_00127 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
HGDKEKEP_00128 4.85e-119 - - - - - - - -
HGDKEKEP_00129 5.82e-20 - - - - - - - -
HGDKEKEP_00130 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HGDKEKEP_00131 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGDKEKEP_00132 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HGDKEKEP_00134 2.06e-204 - - - S - - - aspartate phosphatase
HGDKEKEP_00135 1.17e-18 - - - S - - - aspartate phosphatase
HGDKEKEP_00136 4.15e-108 yycN - - K - - - Acetyltransferase
HGDKEKEP_00137 3.06e-156 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HGDKEKEP_00138 2.71e-260 yycP - - - - - - -
HGDKEKEP_00139 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HGDKEKEP_00141 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGDKEKEP_00142 1.64e-89 - - - - - - - -
HGDKEKEP_00144 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGDKEKEP_00146 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
HGDKEKEP_00147 1.59e-65 - - - L - - - Transposase
HGDKEKEP_00148 3.17e-176 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HGDKEKEP_00149 3.99e-53 - - - - - - - -
HGDKEKEP_00151 1.07e-57 - - - S - - - transposition, DNA-mediated
HGDKEKEP_00152 6.23e-148 - - - S - - - HTH-like domain
HGDKEKEP_00153 0.0 - - - L - - - AAA ATPase domain
HGDKEKEP_00154 0.0 - - - L - - - Superfamily I DNA and RNA helicases
HGDKEKEP_00155 0.0 - - - V - - - Abi-like protein
HGDKEKEP_00156 6.83e-45 - - - - - - - -
HGDKEKEP_00157 6.98e-279 - - - L - - - Transposase
HGDKEKEP_00158 4.78e-152 - - - L - - - Bacterial dnaA protein
HGDKEKEP_00160 7.92e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HGDKEKEP_00161 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGDKEKEP_00162 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGDKEKEP_00163 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HGDKEKEP_00164 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGDKEKEP_00165 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGDKEKEP_00166 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGDKEKEP_00167 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HGDKEKEP_00168 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGDKEKEP_00169 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HGDKEKEP_00170 1.44e-167 yteA - - T - - - COG1734 DnaK suppressor protein
HGDKEKEP_00171 5.69e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HGDKEKEP_00172 4.1e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGDKEKEP_00173 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
HGDKEKEP_00174 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HGDKEKEP_00176 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HGDKEKEP_00177 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HGDKEKEP_00178 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
HGDKEKEP_00179 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HGDKEKEP_00180 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HGDKEKEP_00181 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HGDKEKEP_00182 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HGDKEKEP_00183 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGDKEKEP_00184 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGDKEKEP_00207 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HGDKEKEP_00208 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGDKEKEP_00209 5.44e-74 yuzD - - S - - - protein conserved in bacteria
HGDKEKEP_00210 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HGDKEKEP_00211 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HGDKEKEP_00212 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HGDKEKEP_00213 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGDKEKEP_00214 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HGDKEKEP_00215 2.57e-252 yutH - - S - - - Spore coat protein
HGDKEKEP_00216 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HGDKEKEP_00217 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGDKEKEP_00218 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
HGDKEKEP_00219 3.2e-63 yutD - - S - - - protein conserved in bacteria
HGDKEKEP_00220 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGDKEKEP_00221 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGDKEKEP_00222 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HGDKEKEP_00223 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HGDKEKEP_00224 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
HGDKEKEP_00225 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGDKEKEP_00226 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HGDKEKEP_00227 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HGDKEKEP_00228 1.07e-79 yunG - - - - - - -
HGDKEKEP_00229 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HGDKEKEP_00230 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HGDKEKEP_00231 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HGDKEKEP_00232 4.37e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HGDKEKEP_00233 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HGDKEKEP_00234 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HGDKEKEP_00236 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HGDKEKEP_00237 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HGDKEKEP_00238 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HGDKEKEP_00239 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HGDKEKEP_00240 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HGDKEKEP_00241 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HGDKEKEP_00242 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HGDKEKEP_00243 4.82e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HGDKEKEP_00244 4.42e-216 bsn - - L - - - Ribonuclease
HGDKEKEP_00245 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_00246 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HGDKEKEP_00247 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HGDKEKEP_00248 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HGDKEKEP_00249 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HGDKEKEP_00250 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGDKEKEP_00251 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HGDKEKEP_00252 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HGDKEKEP_00253 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HGDKEKEP_00254 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HGDKEKEP_00256 3.35e-56 - - - - - - - -
HGDKEKEP_00257 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGDKEKEP_00258 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HGDKEKEP_00259 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HGDKEKEP_00260 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HGDKEKEP_00261 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HGDKEKEP_00262 1.82e-276 pbpX - - V - - - Beta-lactamase
HGDKEKEP_00263 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGDKEKEP_00264 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HGDKEKEP_00265 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGDKEKEP_00266 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HGDKEKEP_00267 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HGDKEKEP_00268 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HGDKEKEP_00269 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HGDKEKEP_00270 2.37e-309 ymfH - - S - - - zinc protease
HGDKEKEP_00271 9.47e-299 albE - - S - - - Peptidase M16
HGDKEKEP_00272 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_00273 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_00274 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HGDKEKEP_00275 4.94e-44 - - - S - - - YlzJ-like protein
HGDKEKEP_00276 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HGDKEKEP_00277 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGDKEKEP_00278 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGDKEKEP_00279 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGDKEKEP_00280 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGDKEKEP_00281 1.36e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HGDKEKEP_00282 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HGDKEKEP_00283 1.53e-56 ymxH - - S - - - YlmC YmxH family
HGDKEKEP_00284 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HGDKEKEP_00285 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HGDKEKEP_00286 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HGDKEKEP_00287 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGDKEKEP_00288 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HGDKEKEP_00289 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGDKEKEP_00290 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGDKEKEP_00291 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HGDKEKEP_00292 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGDKEKEP_00293 6.16e-63 ylxQ - - J - - - ribosomal protein
HGDKEKEP_00294 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HGDKEKEP_00295 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HGDKEKEP_00296 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HGDKEKEP_00297 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGDKEKEP_00298 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGDKEKEP_00299 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HGDKEKEP_00300 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HGDKEKEP_00301 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HGDKEKEP_00302 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGDKEKEP_00303 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGDKEKEP_00304 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HGDKEKEP_00305 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGDKEKEP_00306 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HGDKEKEP_00307 6.91e-101 ylxL - - - - - - -
HGDKEKEP_00308 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_00309 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HGDKEKEP_00310 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HGDKEKEP_00311 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HGDKEKEP_00312 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HGDKEKEP_00313 1.49e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HGDKEKEP_00314 1.81e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HGDKEKEP_00315 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HGDKEKEP_00316 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGDKEKEP_00317 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HGDKEKEP_00318 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HGDKEKEP_00319 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HGDKEKEP_00320 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HGDKEKEP_00321 3.99e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HGDKEKEP_00322 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HGDKEKEP_00323 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HGDKEKEP_00324 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGDKEKEP_00325 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HGDKEKEP_00326 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HGDKEKEP_00327 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HGDKEKEP_00328 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HGDKEKEP_00329 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
HGDKEKEP_00330 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HGDKEKEP_00331 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HGDKEKEP_00332 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HGDKEKEP_00333 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HGDKEKEP_00334 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HGDKEKEP_00335 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HGDKEKEP_00336 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HGDKEKEP_00337 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HGDKEKEP_00338 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HGDKEKEP_00339 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HGDKEKEP_00340 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HGDKEKEP_00341 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HGDKEKEP_00342 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGDKEKEP_00343 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGDKEKEP_00344 3.48e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HGDKEKEP_00345 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGDKEKEP_00346 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HGDKEKEP_00347 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HGDKEKEP_00348 0.0 ylqG - - - - - - -
HGDKEKEP_00349 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGDKEKEP_00350 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGDKEKEP_00351 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGDKEKEP_00352 1.98e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HGDKEKEP_00353 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGDKEKEP_00354 3.41e-80 ylqD - - S - - - YlqD protein
HGDKEKEP_00355 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HGDKEKEP_00356 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HGDKEKEP_00357 1.13e-307 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGDKEKEP_00358 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGDKEKEP_00359 1.67e-114 - - - - - - - -
HGDKEKEP_00360 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGDKEKEP_00361 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HGDKEKEP_00362 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGDKEKEP_00363 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGDKEKEP_00364 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HGDKEKEP_00365 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HGDKEKEP_00366 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGDKEKEP_00367 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HGDKEKEP_00368 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGDKEKEP_00369 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HGDKEKEP_00370 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HGDKEKEP_00371 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HGDKEKEP_00372 3.65e-78 yloU - - S - - - protein conserved in bacteria
HGDKEKEP_00373 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HGDKEKEP_00374 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HGDKEKEP_00375 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HGDKEKEP_00376 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGDKEKEP_00377 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HGDKEKEP_00378 1.38e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HGDKEKEP_00379 2.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HGDKEKEP_00380 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGDKEKEP_00381 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGDKEKEP_00382 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGDKEKEP_00383 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGDKEKEP_00384 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGDKEKEP_00385 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGDKEKEP_00386 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HGDKEKEP_00387 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HGDKEKEP_00388 8.41e-202 yloC - - S - - - stress-induced protein
HGDKEKEP_00389 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HGDKEKEP_00390 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HGDKEKEP_00391 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HGDKEKEP_00392 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HGDKEKEP_00393 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HGDKEKEP_00394 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HGDKEKEP_00395 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HGDKEKEP_00396 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HGDKEKEP_00397 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HGDKEKEP_00398 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGDKEKEP_00399 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGDKEKEP_00400 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGDKEKEP_00401 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HGDKEKEP_00402 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HGDKEKEP_00403 3.76e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HGDKEKEP_00404 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGDKEKEP_00405 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HGDKEKEP_00406 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HGDKEKEP_00407 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGDKEKEP_00408 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HGDKEKEP_00409 3.85e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGDKEKEP_00410 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HGDKEKEP_00412 3.65e-81 ynaC - - - - - - -
HGDKEKEP_00413 9.3e-51 ynaC - - - - - - -
HGDKEKEP_00414 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
HGDKEKEP_00415 4.13e-51 - - - - - - - -
HGDKEKEP_00416 1.46e-105 - - - - - - - -
HGDKEKEP_00418 1.68e-13 - - - - - - - -
HGDKEKEP_00420 4.6e-309 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HGDKEKEP_00421 1.68e-53 - - - - - - - -
HGDKEKEP_00422 3.69e-32 - - - - - - - -
HGDKEKEP_00423 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HGDKEKEP_00424 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HGDKEKEP_00425 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HGDKEKEP_00426 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGDKEKEP_00427 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HGDKEKEP_00428 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGDKEKEP_00429 2.24e-141 - - - - - - - -
HGDKEKEP_00430 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGDKEKEP_00431 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGDKEKEP_00432 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HGDKEKEP_00433 1.2e-30 ymzA - - - - - - -
HGDKEKEP_00434 1.63e-31 - - - - - - - -
HGDKEKEP_00435 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HGDKEKEP_00436 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGDKEKEP_00437 5.41e-76 ymaF - - S - - - YmaF family
HGDKEKEP_00439 2.45e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HGDKEKEP_00440 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HGDKEKEP_00441 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HGDKEKEP_00442 3.96e-163 ymaC - - S - - - Replication protein
HGDKEKEP_00444 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HGDKEKEP_00445 1.96e-209 - - - S - - - Metallo-beta-lactamase superfamily
HGDKEKEP_00446 8.03e-81 ymzB - - - - - - -
HGDKEKEP_00447 1.02e-134 pksA - - K - - - Transcriptional regulator
HGDKEKEP_00448 9.3e-126 ymcC - - S - - - Membrane
HGDKEKEP_00449 2.23e-90 - - - S - - - Regulatory protein YrvL
HGDKEKEP_00450 1.12e-134 yuaD - - - - - - -
HGDKEKEP_00451 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HGDKEKEP_00452 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGDKEKEP_00453 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HGDKEKEP_00454 5.83e-118 yuaB - - - - - - -
HGDKEKEP_00455 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HGDKEKEP_00456 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HGDKEKEP_00457 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HGDKEKEP_00458 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGDKEKEP_00459 0.0 yubD - - P - - - Major Facilitator Superfamily
HGDKEKEP_00460 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HGDKEKEP_00462 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HGDKEKEP_00463 1.73e-252 yubA - - S - - - transporter activity
HGDKEKEP_00464 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGDKEKEP_00465 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HGDKEKEP_00466 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HGDKEKEP_00467 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HGDKEKEP_00468 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGDKEKEP_00469 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HGDKEKEP_00470 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00471 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00472 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00473 2.02e-284 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00474 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00475 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HGDKEKEP_00476 5e-48 - - - - - - - -
HGDKEKEP_00477 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGDKEKEP_00478 7.23e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGDKEKEP_00479 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HGDKEKEP_00480 2.16e-48 - - - - - - - -
HGDKEKEP_00481 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
HGDKEKEP_00482 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HGDKEKEP_00483 2.75e-91 yugN - - S - - - YugN-like family
HGDKEKEP_00485 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HGDKEKEP_00486 1.2e-285 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HGDKEKEP_00487 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HGDKEKEP_00488 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HGDKEKEP_00489 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HGDKEKEP_00490 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HGDKEKEP_00491 6.74e-112 alaR - - K - - - Transcriptional regulator
HGDKEKEP_00492 1.18e-119 yugF - - I - - - Hydrolase
HGDKEKEP_00494 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
HGDKEKEP_00495 6.29e-10 - - - S - - - DegQ (SacQ) family
HGDKEKEP_00497 8.73e-09 yuzC - - - - - - -
HGDKEKEP_00498 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HGDKEKEP_00499 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGDKEKEP_00500 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HGDKEKEP_00501 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
HGDKEKEP_00502 1.63e-52 yueH - - S - - - YueH-like protein
HGDKEKEP_00503 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HGDKEKEP_00504 1.35e-244 yueF - - S - - - transporter activity
HGDKEKEP_00505 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
HGDKEKEP_00506 1.19e-32 - - - S - - - Protein of unknown function (DUF2642)
HGDKEKEP_00507 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HGDKEKEP_00508 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_00509 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
HGDKEKEP_00510 0.0 yueB - - S - - - type VII secretion protein EsaA
HGDKEKEP_00511 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HGDKEKEP_00512 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HGDKEKEP_00513 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HGDKEKEP_00514 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HGDKEKEP_00515 2.96e-292 yukF - - QT - - - Transcriptional regulator
HGDKEKEP_00516 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HGDKEKEP_00517 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HGDKEKEP_00518 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HGDKEKEP_00519 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_00520 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HGDKEKEP_00521 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HGDKEKEP_00522 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HGDKEKEP_00523 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_00524 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
HGDKEKEP_00525 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HGDKEKEP_00526 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HGDKEKEP_00527 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HGDKEKEP_00528 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HGDKEKEP_00529 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HGDKEKEP_00530 2.69e-148 yuiC - - S - - - protein conserved in bacteria
HGDKEKEP_00531 1.97e-46 yuiB - - S - - - Putative membrane protein
HGDKEKEP_00532 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGDKEKEP_00533 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HGDKEKEP_00535 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGDKEKEP_00536 1.36e-123 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HGDKEKEP_00537 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HGDKEKEP_00538 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGDKEKEP_00539 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGDKEKEP_00540 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGDKEKEP_00541 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HGDKEKEP_00542 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HGDKEKEP_00543 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HGDKEKEP_00544 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HGDKEKEP_00545 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGDKEKEP_00546 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGDKEKEP_00547 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
HGDKEKEP_00548 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
HGDKEKEP_00549 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HGDKEKEP_00550 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HGDKEKEP_00551 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HGDKEKEP_00552 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HGDKEKEP_00553 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGDKEKEP_00554 1.92e-08 - - - - - - - -
HGDKEKEP_00555 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HGDKEKEP_00556 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HGDKEKEP_00557 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGDKEKEP_00558 4.16e-198 yitS - - S - - - protein conserved in bacteria
HGDKEKEP_00559 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HGDKEKEP_00560 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HGDKEKEP_00561 2.9e-118 - - - - - - - -
HGDKEKEP_00562 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
HGDKEKEP_00563 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HGDKEKEP_00564 1.42e-218 - - - - - - - -
HGDKEKEP_00565 2.41e-121 - - - - - - - -
HGDKEKEP_00566 3.91e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HGDKEKEP_00567 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HGDKEKEP_00568 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HGDKEKEP_00569 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
HGDKEKEP_00570 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
HGDKEKEP_00571 1.52e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGDKEKEP_00572 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HGDKEKEP_00573 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_00574 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HGDKEKEP_00575 9.94e-120 yisT - - S - - - DinB family
HGDKEKEP_00576 5.32e-242 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HGDKEKEP_00577 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HGDKEKEP_00578 1.41e-207 yisR - - K - - - Transcriptional regulator
HGDKEKEP_00579 1.01e-310 yisQ - - V - - - Mate efflux family protein
HGDKEKEP_00580 3.44e-142 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HGDKEKEP_00581 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HGDKEKEP_00582 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
HGDKEKEP_00583 1.76e-10 - - - - - - - -
HGDKEKEP_00584 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HGDKEKEP_00585 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HGDKEKEP_00588 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HGDKEKEP_00589 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_00592 5.28e-79 - - - - - - - -
HGDKEKEP_00593 4.26e-43 - - - S - - - Phage integrase family
HGDKEKEP_00594 2.09e-81 - - - S - - - Phage integrase family
HGDKEKEP_00596 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HGDKEKEP_00597 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGDKEKEP_00598 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HGDKEKEP_00599 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HGDKEKEP_00600 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HGDKEKEP_00601 4.9e-48 yvzC - - K - - - transcriptional
HGDKEKEP_00602 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HGDKEKEP_00603 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGDKEKEP_00604 3.85e-72 yvaP - - K - - - transcriptional
HGDKEKEP_00605 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_00606 3.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGDKEKEP_00607 7.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGDKEKEP_00608 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGDKEKEP_00609 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGDKEKEP_00610 3.28e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HGDKEKEP_00611 1.13e-135 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGDKEKEP_00612 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HGDKEKEP_00613 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HGDKEKEP_00614 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HGDKEKEP_00615 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HGDKEKEP_00616 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HGDKEKEP_00617 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
HGDKEKEP_00618 2.66e-155 yvbI - - M - - - Membrane
HGDKEKEP_00619 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HGDKEKEP_00620 9.77e-106 yvbK - - K - - - acetyltransferase
HGDKEKEP_00621 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGDKEKEP_00622 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HGDKEKEP_00623 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGDKEKEP_00624 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HGDKEKEP_00625 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGDKEKEP_00626 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGDKEKEP_00627 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_00628 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HGDKEKEP_00629 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGDKEKEP_00630 1.99e-205 yvbU - - K - - - Transcriptional regulator
HGDKEKEP_00631 5.59e-198 yvbV - - EG - - - EamA-like transporter family
HGDKEKEP_00632 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_00633 2.7e-187 - - - S - - - Glycosyl hydrolase
HGDKEKEP_00634 6.88e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGDKEKEP_00635 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HGDKEKEP_00636 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HGDKEKEP_00637 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
HGDKEKEP_00638 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
HGDKEKEP_00639 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_00640 1.09e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_00641 8.31e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HGDKEKEP_00642 1.1e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HGDKEKEP_00643 8.47e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HGDKEKEP_00644 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HGDKEKEP_00645 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HGDKEKEP_00646 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HGDKEKEP_00647 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HGDKEKEP_00648 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HGDKEKEP_00649 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HGDKEKEP_00650 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_00651 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HGDKEKEP_00652 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HGDKEKEP_00653 7.05e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HGDKEKEP_00654 5.69e-44 yvfG - - S - - - YvfG protein
HGDKEKEP_00655 3.07e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HGDKEKEP_00656 1.06e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HGDKEKEP_00657 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HGDKEKEP_00658 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGDKEKEP_00659 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_00660 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGDKEKEP_00661 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HGDKEKEP_00662 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HGDKEKEP_00663 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HGDKEKEP_00664 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HGDKEKEP_00665 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGDKEKEP_00666 5.25e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HGDKEKEP_00667 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HGDKEKEP_00668 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HGDKEKEP_00669 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HGDKEKEP_00670 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HGDKEKEP_00671 1.85e-72 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HGDKEKEP_00672 6.68e-19 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HGDKEKEP_00673 2.17e-224 pbpE - - V - - - Beta-lactamase
HGDKEKEP_00674 3.77e-79 pbpE - - V - - - Beta-lactamase
HGDKEKEP_00675 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HGDKEKEP_00676 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HGDKEKEP_00677 0.0 ybeC - - E - - - amino acid
HGDKEKEP_00678 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
HGDKEKEP_00679 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HGDKEKEP_00680 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HGDKEKEP_00681 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
HGDKEKEP_00683 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGDKEKEP_00684 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGDKEKEP_00685 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGDKEKEP_00686 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HGDKEKEP_00687 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
HGDKEKEP_00688 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HGDKEKEP_00689 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HGDKEKEP_00690 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HGDKEKEP_00691 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HGDKEKEP_00692 1.54e-221 yvdE - - K - - - Transcriptional regulator
HGDKEKEP_00693 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HGDKEKEP_00694 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HGDKEKEP_00695 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HGDKEKEP_00696 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HGDKEKEP_00697 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGDKEKEP_00698 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HGDKEKEP_00699 3.67e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_00700 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HGDKEKEP_00701 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_00702 7.42e-29 - - - - - - - -
HGDKEKEP_00703 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HGDKEKEP_00704 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HGDKEKEP_00705 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HGDKEKEP_00706 5.52e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HGDKEKEP_00707 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HGDKEKEP_00708 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HGDKEKEP_00709 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGDKEKEP_00710 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HGDKEKEP_00711 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HGDKEKEP_00712 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HGDKEKEP_00714 0.0 - - - - - - - -
HGDKEKEP_00715 3.7e-111 - - - - - - - -
HGDKEKEP_00716 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HGDKEKEP_00717 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HGDKEKEP_00718 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGDKEKEP_00719 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGDKEKEP_00720 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HGDKEKEP_00721 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGDKEKEP_00722 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HGDKEKEP_00723 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGDKEKEP_00724 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
HGDKEKEP_00725 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HGDKEKEP_00726 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGDKEKEP_00727 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGDKEKEP_00728 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HGDKEKEP_00729 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGDKEKEP_00730 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HGDKEKEP_00731 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGDKEKEP_00732 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGDKEKEP_00733 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGDKEKEP_00734 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGDKEKEP_00735 4.32e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HGDKEKEP_00736 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGDKEKEP_00737 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGDKEKEP_00738 8.33e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HGDKEKEP_00739 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HGDKEKEP_00740 3.77e-97 - - - S - - - Bacterial PH domain
HGDKEKEP_00741 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HGDKEKEP_00742 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HGDKEKEP_00752 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HGDKEKEP_00753 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGDKEKEP_00757 9.33e-108 - - - S - - - Protein of unknown function (DUF3800)
HGDKEKEP_00758 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HGDKEKEP_00759 1.79e-74 - - - S - - - Bacteriophage holin family
HGDKEKEP_00762 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HGDKEKEP_00763 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGDKEKEP_00764 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGDKEKEP_00765 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HGDKEKEP_00766 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGDKEKEP_00767 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HGDKEKEP_00768 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
HGDKEKEP_00769 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HGDKEKEP_00770 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HGDKEKEP_00771 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HGDKEKEP_00772 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HGDKEKEP_00773 3.36e-218 alsR - - K - - - LysR substrate binding domain
HGDKEKEP_00774 8.01e-263 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGDKEKEP_00775 1.06e-162 ywrJ - - - - - - -
HGDKEKEP_00776 3.02e-44 cotB - - - ko:K06325 - ko00000 -
HGDKEKEP_00777 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
HGDKEKEP_00778 1e-17 - - - - - - - -
HGDKEKEP_00779 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGDKEKEP_00780 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HGDKEKEP_00781 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HGDKEKEP_00782 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HGDKEKEP_00783 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HGDKEKEP_00784 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HGDKEKEP_00786 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
HGDKEKEP_00787 4.73e-209 - - - K - - - Transcriptional regulator
HGDKEKEP_00788 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HGDKEKEP_00790 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
HGDKEKEP_00791 4.93e-95 ywqJ - - S - - - Pre-toxin TG
HGDKEKEP_00792 1.3e-23 - - - - - - - -
HGDKEKEP_00793 2.5e-26 - - - - - - - -
HGDKEKEP_00794 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HGDKEKEP_00795 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HGDKEKEP_00797 9.48e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
HGDKEKEP_00798 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGDKEKEP_00799 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HGDKEKEP_00800 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HGDKEKEP_00801 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HGDKEKEP_00802 3.6e-25 - - - - - - - -
HGDKEKEP_00803 0.0 ywqB - - S - - - SWIM zinc finger
HGDKEKEP_00804 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGDKEKEP_00805 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGDKEKEP_00806 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGDKEKEP_00807 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HGDKEKEP_00808 2.79e-40 ywpG - - - - - - -
HGDKEKEP_00809 3.59e-88 ywpF - - S - - - YwpF-like protein
HGDKEKEP_00810 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HGDKEKEP_00811 4.66e-186 ywpD - - T - - - Histidine kinase
HGDKEKEP_00812 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGDKEKEP_00813 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGDKEKEP_00814 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HGDKEKEP_00815 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HGDKEKEP_00816 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HGDKEKEP_00817 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HGDKEKEP_00818 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HGDKEKEP_00819 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HGDKEKEP_00820 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_00821 3.25e-309 ywoF - - P - - - Right handed beta helix region
HGDKEKEP_00822 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HGDKEKEP_00823 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
HGDKEKEP_00824 1.04e-133 yjgF - - Q - - - Isochorismatase family
HGDKEKEP_00825 7.16e-101 - - - - - - - -
HGDKEKEP_00826 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HGDKEKEP_00827 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HGDKEKEP_00828 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HGDKEKEP_00829 9.05e-93 ywnJ - - S - - - VanZ like family
HGDKEKEP_00830 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HGDKEKEP_00831 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HGDKEKEP_00832 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
HGDKEKEP_00833 6.7e-234 - - - M - - - NeuB family
HGDKEKEP_00834 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
HGDKEKEP_00835 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGDKEKEP_00836 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HGDKEKEP_00837 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HGDKEKEP_00838 1.42e-112 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HGDKEKEP_00839 6.73e-19 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HGDKEKEP_00840 4.58e-85 ywnA - - K - - - Transcriptional regulator
HGDKEKEP_00841 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HGDKEKEP_00842 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HGDKEKEP_00843 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HGDKEKEP_00844 0.000282 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HGDKEKEP_00845 2.15e-19 csbD - - K - - - CsbD-like
HGDKEKEP_00846 8.55e-110 ywmF - - S - - - Peptidase M50
HGDKEKEP_00847 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_00848 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGDKEKEP_00849 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGDKEKEP_00851 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGDKEKEP_00852 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGDKEKEP_00853 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HGDKEKEP_00854 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGDKEKEP_00855 6.59e-172 ywmB - - S - - - TATA-box binding
HGDKEKEP_00856 4.54e-45 ywzB - - S - - - membrane
HGDKEKEP_00857 2.92e-113 ywmA - - - - - - -
HGDKEKEP_00858 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HGDKEKEP_00859 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGDKEKEP_00860 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGDKEKEP_00861 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGDKEKEP_00862 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGDKEKEP_00863 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGDKEKEP_00864 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGDKEKEP_00865 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HGDKEKEP_00866 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HGDKEKEP_00867 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGDKEKEP_00868 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGDKEKEP_00869 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HGDKEKEP_00870 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HGDKEKEP_00871 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGDKEKEP_00872 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HGDKEKEP_00873 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGDKEKEP_00874 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HGDKEKEP_00875 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HGDKEKEP_00876 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGDKEKEP_00878 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGDKEKEP_00879 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGDKEKEP_00880 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_00881 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HGDKEKEP_00882 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGDKEKEP_00883 7.4e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HGDKEKEP_00884 2.79e-213 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HGDKEKEP_00885 4.62e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGDKEKEP_00886 8.96e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HGDKEKEP_00889 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGDKEKEP_00890 6.32e-99 ygaO - - - - - - -
HGDKEKEP_00891 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_00893 1.07e-144 yhzB - - S - - - B3/4 domain
HGDKEKEP_00894 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGDKEKEP_00895 9.27e-224 yhbB - - S - - - Putative amidase domain
HGDKEKEP_00896 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGDKEKEP_00897 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
HGDKEKEP_00898 1.53e-94 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HGDKEKEP_00899 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HGDKEKEP_00900 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HGDKEKEP_00901 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HGDKEKEP_00902 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HGDKEKEP_00903 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HGDKEKEP_00904 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HGDKEKEP_00905 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HGDKEKEP_00906 3.95e-59 yhcC - - - - - - -
HGDKEKEP_00907 2.06e-69 - - - - - - - -
HGDKEKEP_00908 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_00909 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_00910 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_00911 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGDKEKEP_00912 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HGDKEKEP_00913 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HGDKEKEP_00914 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HGDKEKEP_00915 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGDKEKEP_00916 1.08e-219 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGDKEKEP_00917 1.5e-81 - - - S - - - Immunity protein 70
HGDKEKEP_00921 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
HGDKEKEP_00923 4.39e-37 yddA - - - - - - -
HGDKEKEP_00927 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
HGDKEKEP_00928 9.78e-54 yddC - - - - - - -
HGDKEKEP_00929 6.91e-118 yddD - - S - - - TcpE family
HGDKEKEP_00930 1.59e-270 yddE - - S - - - AAA-like domain
HGDKEKEP_00931 2.21e-242 yddE - - S - - - AAA-like domain
HGDKEKEP_00932 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
HGDKEKEP_00933 0.0 yddG - - S - - - maturation of SSU-rRNA
HGDKEKEP_00934 1.03e-237 yddH - - M - - - Lysozyme-like
HGDKEKEP_00935 3.19e-111 yddI - - - - - - -
HGDKEKEP_00936 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
HGDKEKEP_00937 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
HGDKEKEP_00938 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_00940 9.39e-63 yhcM - - - - - - -
HGDKEKEP_00941 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGDKEKEP_00942 3.38e-216 yhcP - - - - - - -
HGDKEKEP_00943 7.05e-124 yhcQ - - M - - - Spore coat protein
HGDKEKEP_00944 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGDKEKEP_00945 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HGDKEKEP_00946 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HGDKEKEP_00947 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HGDKEKEP_00948 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
HGDKEKEP_00949 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
HGDKEKEP_00950 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGDKEKEP_00951 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGDKEKEP_00952 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HGDKEKEP_00953 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HGDKEKEP_00954 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGDKEKEP_00955 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HGDKEKEP_00956 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HGDKEKEP_00957 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_00958 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_00959 1.9e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HGDKEKEP_00960 1.65e-51 yhdB - - S - - - YhdB-like protein
HGDKEKEP_00961 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
HGDKEKEP_00962 1.32e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGDKEKEP_00963 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HGDKEKEP_00964 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
HGDKEKEP_00965 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HGDKEKEP_00966 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HGDKEKEP_00967 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HGDKEKEP_00968 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGDKEKEP_00969 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HGDKEKEP_00970 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
HGDKEKEP_00971 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HGDKEKEP_00972 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGDKEKEP_00973 2.51e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGDKEKEP_00974 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGDKEKEP_00975 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGDKEKEP_00976 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGDKEKEP_00977 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HGDKEKEP_00978 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGDKEKEP_00979 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGDKEKEP_00980 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGDKEKEP_00981 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HGDKEKEP_00982 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGDKEKEP_00983 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HGDKEKEP_00984 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGDKEKEP_00985 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGDKEKEP_00986 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HGDKEKEP_00987 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HGDKEKEP_00988 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGDKEKEP_00989 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGDKEKEP_00990 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGDKEKEP_00991 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGDKEKEP_00992 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGDKEKEP_00993 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGDKEKEP_00994 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGDKEKEP_00995 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGDKEKEP_00996 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGDKEKEP_00997 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HGDKEKEP_00998 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGDKEKEP_00999 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGDKEKEP_01000 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGDKEKEP_01001 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGDKEKEP_01002 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGDKEKEP_01003 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGDKEKEP_01004 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HGDKEKEP_01005 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGDKEKEP_01006 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HGDKEKEP_01007 1.83e-230 ybaC - - S - - - Alpha/beta hydrolase family
HGDKEKEP_01008 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGDKEKEP_01009 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGDKEKEP_01010 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGDKEKEP_01011 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGDKEKEP_01012 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HGDKEKEP_01013 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGDKEKEP_01014 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGDKEKEP_01015 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HGDKEKEP_01016 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGDKEKEP_01017 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGDKEKEP_01018 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGDKEKEP_01019 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGDKEKEP_01020 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HGDKEKEP_01021 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGDKEKEP_01022 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HGDKEKEP_01023 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HGDKEKEP_01024 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGDKEKEP_01025 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGDKEKEP_01026 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HGDKEKEP_01027 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HGDKEKEP_01028 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGDKEKEP_01029 1.82e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HGDKEKEP_01030 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HGDKEKEP_01031 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HGDKEKEP_01032 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HGDKEKEP_01033 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGDKEKEP_01034 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HGDKEKEP_01035 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HGDKEKEP_01036 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HGDKEKEP_01037 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HGDKEKEP_01038 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HGDKEKEP_01039 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HGDKEKEP_01040 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HGDKEKEP_01041 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HGDKEKEP_01042 1.28e-37 ybyB - - - - - - -
HGDKEKEP_01043 0.0 ybeC - - E - - - amino acid
HGDKEKEP_01044 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HGDKEKEP_01045 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HGDKEKEP_01046 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HGDKEKEP_01047 8.65e-202 ybfA - - K - - - FR47-like protein
HGDKEKEP_01048 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_01049 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_01052 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HGDKEKEP_01053 5.01e-133 ybfH - - EG - - - EamA-like transporter family
HGDKEKEP_01054 2.88e-185 ybfI - - K - - - AraC-like ligand binding domain
HGDKEKEP_01055 3.63e-43 - - - K - - - sigma factor activity
HGDKEKEP_01056 2.73e-28 xhlB - - S - - - SPP1 phage holin
HGDKEKEP_01057 4.74e-185 - - GH19 M ko:K03791 - ko00000 Lysin motif
HGDKEKEP_01058 2.61e-73 - - - - - - - -
HGDKEKEP_01059 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGDKEKEP_01060 3.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
HGDKEKEP_01062 1.31e-212 - - - S - - - Alpha/beta hydrolase family
HGDKEKEP_01063 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGDKEKEP_01064 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HGDKEKEP_01065 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HGDKEKEP_01066 2.25e-59 ybfN - - - - - - -
HGDKEKEP_01067 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HGDKEKEP_01068 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01069 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HGDKEKEP_01070 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGDKEKEP_01071 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_01072 4.29e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGDKEKEP_01073 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HGDKEKEP_01075 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HGDKEKEP_01076 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGDKEKEP_01077 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HGDKEKEP_01078 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HGDKEKEP_01079 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HGDKEKEP_01080 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HGDKEKEP_01081 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_01082 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HGDKEKEP_01083 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HGDKEKEP_01084 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGDKEKEP_01085 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_01086 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HGDKEKEP_01087 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HGDKEKEP_01088 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HGDKEKEP_01089 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HGDKEKEP_01090 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HGDKEKEP_01091 2.85e-215 eamA1 - - EG - - - spore germination
HGDKEKEP_01092 4.8e-149 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_01093 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
HGDKEKEP_01094 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HGDKEKEP_01095 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HGDKEKEP_01096 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_01097 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGDKEKEP_01098 1.26e-18 - - - - - - - -
HGDKEKEP_01100 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
HGDKEKEP_01102 2.94e-17 - - - EGP - - - Major Facilitator
HGDKEKEP_01103 6.4e-09 - - - J - - - O-methyltransferase
HGDKEKEP_01104 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
HGDKEKEP_01105 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HGDKEKEP_01107 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HGDKEKEP_01108 3.48e-88 - - - S - - - YusW-like protein
HGDKEKEP_01109 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGDKEKEP_01110 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HGDKEKEP_01111 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HGDKEKEP_01112 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_01113 4.86e-84 yusQ - - S - - - Tautomerase enzyme
HGDKEKEP_01114 0.0 yusP - - P - - - Major facilitator superfamily
HGDKEKEP_01115 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HGDKEKEP_01116 8.66e-70 yusN - - M - - - Coat F domain
HGDKEKEP_01117 2.23e-54 - - - - - - - -
HGDKEKEP_01118 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HGDKEKEP_01119 1.11e-13 - - - S - - - YuzL-like protein
HGDKEKEP_01120 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HGDKEKEP_01121 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HGDKEKEP_01122 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HGDKEKEP_01123 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HGDKEKEP_01124 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HGDKEKEP_01125 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
HGDKEKEP_01126 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HGDKEKEP_01127 8.14e-73 yusE - - CO - - - Thioredoxin
HGDKEKEP_01128 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HGDKEKEP_01129 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGDKEKEP_01130 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HGDKEKEP_01131 1.96e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HGDKEKEP_01132 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGDKEKEP_01133 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HGDKEKEP_01134 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HGDKEKEP_01135 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGDKEKEP_01136 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HGDKEKEP_01137 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HGDKEKEP_01138 1.79e-149 - - - L - - - Belongs to the 'phage' integrase family
HGDKEKEP_01142 7.24e-60 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_01143 1.7e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_01144 4.59e-23 - - - - - - - -
HGDKEKEP_01146 3.42e-87 - - - L - - - dnaD_dom DnaD domain protein
HGDKEKEP_01147 2.01e-64 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA replication protein
HGDKEKEP_01149 1.88e-09 - - - - - - - -
HGDKEKEP_01150 1.73e-13 - - - - - - - -
HGDKEKEP_01151 8.16e-77 - - - O - - - Papain family cysteine protease
HGDKEKEP_01153 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
HGDKEKEP_01154 3.82e-37 - - - - - - - -
HGDKEKEP_01156 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGDKEKEP_01158 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HGDKEKEP_01160 1.54e-121 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGDKEKEP_01161 5.98e-72 ypuD - - - - - - -
HGDKEKEP_01162 3.42e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGDKEKEP_01163 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HGDKEKEP_01164 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGDKEKEP_01165 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGDKEKEP_01166 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_01167 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HGDKEKEP_01168 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGDKEKEP_01169 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGDKEKEP_01170 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HGDKEKEP_01171 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGDKEKEP_01172 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HGDKEKEP_01173 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HGDKEKEP_01174 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HGDKEKEP_01175 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HGDKEKEP_01176 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HGDKEKEP_01177 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HGDKEKEP_01178 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_01179 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_01180 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_01181 8.11e-17 rsiX - - - - - - -
HGDKEKEP_01182 2.96e-135 rsiX - - - - - - -
HGDKEKEP_01183 9.27e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGDKEKEP_01184 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGDKEKEP_01185 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGDKEKEP_01186 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HGDKEKEP_01187 3.14e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HGDKEKEP_01188 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGDKEKEP_01189 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HGDKEKEP_01190 5.04e-148 ypbE - - M - - - Lysin motif
HGDKEKEP_01191 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HGDKEKEP_01192 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HGDKEKEP_01193 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HGDKEKEP_01194 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGDKEKEP_01195 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HGDKEKEP_01196 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HGDKEKEP_01197 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HGDKEKEP_01198 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HGDKEKEP_01199 2.02e-138 ypfA - - M - - - Flagellar protein YcgR
HGDKEKEP_01200 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
HGDKEKEP_01201 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HGDKEKEP_01202 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HGDKEKEP_01203 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGDKEKEP_01204 3.89e-11 - - - L - - - COG2963 Transposase and inactivated derivatives
HGDKEKEP_01206 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HGDKEKEP_01207 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
HGDKEKEP_01208 7.8e-49 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HGDKEKEP_01209 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HGDKEKEP_01210 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_01211 1.07e-08 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_01212 1.15e-204 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_01213 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HGDKEKEP_01214 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HGDKEKEP_01215 1.14e-311 yoeA - - V - - - MATE efflux family protein
HGDKEKEP_01216 8.34e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HGDKEKEP_01218 1.14e-124 - - - L - - - Integrase
HGDKEKEP_01219 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HGDKEKEP_01220 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HGDKEKEP_01221 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01222 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HGDKEKEP_01223 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HGDKEKEP_01224 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HGDKEKEP_01225 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01226 2.05e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGDKEKEP_01227 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGDKEKEP_01228 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGDKEKEP_01229 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HGDKEKEP_01230 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_01231 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HGDKEKEP_01232 7.05e-172 yoxB - - - - - - -
HGDKEKEP_01233 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGDKEKEP_01234 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_01235 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_01236 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HGDKEKEP_01237 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGDKEKEP_01238 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
HGDKEKEP_01239 2.23e-112 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HGDKEKEP_01240 7.71e-128 - - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_01241 0.0 - - - I - - - PLD-like domain
HGDKEKEP_01242 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_01243 1.38e-16 - - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_01244 9.73e-194 - - - S - - - membrane
HGDKEKEP_01245 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
HGDKEKEP_01246 4.34e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
HGDKEKEP_01247 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HGDKEKEP_01248 5.84e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HGDKEKEP_01249 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
HGDKEKEP_01251 7.51e-205 - - - P - - - Catalase
HGDKEKEP_01252 2.56e-34 - - - S - - - Protein of unknown function (DUF2642)
HGDKEKEP_01253 2.28e-13 - - - S - - - TIGRFAM germination protein, Ger(x)C family
HGDKEKEP_01254 5.92e-194 - - - EG - - - Spore germination protein
HGDKEKEP_01255 5.09e-42 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HGDKEKEP_01256 2.2e-100 - - - - - - - -
HGDKEKEP_01257 5.32e-60 - - - L - - - Transposase and inactivated derivatives, TnpA family
HGDKEKEP_01258 1.88e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HGDKEKEP_01259 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HGDKEKEP_01260 3.56e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HGDKEKEP_01261 1.79e-145 yoaK - - S - - - Membrane
HGDKEKEP_01262 1.79e-66 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HGDKEKEP_01263 2.87e-119 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HGDKEKEP_01264 1.27e-105 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HGDKEKEP_01266 3.1e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HGDKEKEP_01269 2.01e-108 - - - - - - - -
HGDKEKEP_01270 5.78e-215 yoaR - - V - - - vancomycin resistance protein
HGDKEKEP_01271 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HGDKEKEP_01272 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01273 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
HGDKEKEP_01274 1.35e-202 yoaU - - K - - - LysR substrate binding domain
HGDKEKEP_01275 3.7e-201 yoaV - - EG - - - EamA-like transporter family
HGDKEKEP_01276 1.89e-100 yoaW - - - - - - -
HGDKEKEP_01277 4.88e-147 lin0465 - - S - - - DJ-1/PfpI family
HGDKEKEP_01278 8.51e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HGDKEKEP_01281 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HGDKEKEP_01282 2.62e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HGDKEKEP_01283 2.11e-49 - - - S - - - TM2 domain
HGDKEKEP_01284 1.73e-70 - - - K - - - Helix-turn-helix
HGDKEKEP_01287 1.45e-38 - - - - - - - -
HGDKEKEP_01291 4.91e-53 - - - - - - - -
HGDKEKEP_01292 5.2e-19 - - - K - - - Transcriptional regulator
HGDKEKEP_01293 3.72e-91 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HGDKEKEP_01298 1.65e-30 yqaO - - S - - - Phage-like element PBSX protein XtrA
HGDKEKEP_01300 3.86e-72 - - - S - - - Protein of unknown function (DUF1064)
HGDKEKEP_01303 1.19e-162 yqaM - - L - - - IstB-like ATP binding protein
HGDKEKEP_01304 3.87e-45 yqaL - - L - - - DnaD domain protein
HGDKEKEP_01305 3.08e-149 recT - - L ko:K07455 - ko00000,ko03400 RecT family
HGDKEKEP_01306 1.55e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
HGDKEKEP_01311 2.69e-88 - - - - - - - -
HGDKEKEP_01312 1.64e-64 - - - S - - - DNA binding
HGDKEKEP_01314 1.94e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_01315 1.04e-32 - - - K - - - sequence-specific DNA binding
HGDKEKEP_01316 4.27e-128 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HGDKEKEP_01317 3.92e-99 - - - S - - - Bacterial PH domain
HGDKEKEP_01318 3.35e-63 xkdA - - E - - - IrrE N-terminal-like domain
HGDKEKEP_01319 5.95e-306 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_01320 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HGDKEKEP_01321 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_01322 6.21e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_01323 5.86e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HGDKEKEP_01324 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01325 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGDKEKEP_01326 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HGDKEKEP_01327 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_01328 1.97e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HGDKEKEP_01329 2.21e-228 ykvZ - - K - - - Transcriptional regulator
HGDKEKEP_01330 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HGDKEKEP_01331 3.99e-09 - - - - - - - -
HGDKEKEP_01332 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HGDKEKEP_01333 1.12e-114 stoA - - CO - - - thiol-disulfide
HGDKEKEP_01334 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_01335 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HGDKEKEP_01336 2.6e-39 - - - - - - - -
HGDKEKEP_01337 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HGDKEKEP_01338 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
HGDKEKEP_01339 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HGDKEKEP_01340 2.41e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HGDKEKEP_01341 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HGDKEKEP_01342 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HGDKEKEP_01343 8.23e-228 ykvI - - S - - - membrane
HGDKEKEP_01344 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HGDKEKEP_01345 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HGDKEKEP_01346 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HGDKEKEP_01347 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HGDKEKEP_01348 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HGDKEKEP_01349 5.87e-74 eag - - - - - - -
HGDKEKEP_01351 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HGDKEKEP_01352 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGDKEKEP_01353 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HGDKEKEP_01354 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HGDKEKEP_01355 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HGDKEKEP_01356 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HGDKEKEP_01357 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HGDKEKEP_01358 3.19e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGDKEKEP_01359 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HGDKEKEP_01360 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
HGDKEKEP_01361 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_01362 7.75e-258 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HGDKEKEP_01363 6.06e-61 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HGDKEKEP_01364 1.05e-250 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGDKEKEP_01365 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGDKEKEP_01366 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGDKEKEP_01367 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGDKEKEP_01368 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HGDKEKEP_01369 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HGDKEKEP_01370 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HGDKEKEP_01371 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HGDKEKEP_01373 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HGDKEKEP_01374 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HGDKEKEP_01375 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
HGDKEKEP_01376 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HGDKEKEP_01377 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGDKEKEP_01378 5.04e-305 ygxB - - M - - - Conserved TM helix
HGDKEKEP_01379 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HGDKEKEP_01380 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HGDKEKEP_01381 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGDKEKEP_01382 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01383 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGDKEKEP_01384 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_01385 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
HGDKEKEP_01386 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGDKEKEP_01387 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_01388 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_01389 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HGDKEKEP_01390 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
HGDKEKEP_01391 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_01392 1.12e-242 yhdN - - C - - - Aldo keto reductase
HGDKEKEP_01393 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGDKEKEP_01394 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGDKEKEP_01395 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HGDKEKEP_01396 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HGDKEKEP_01397 1.21e-169 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HGDKEKEP_01398 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HGDKEKEP_01399 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGDKEKEP_01400 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGDKEKEP_01401 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HGDKEKEP_01402 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HGDKEKEP_01403 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HGDKEKEP_01404 9.4e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HGDKEKEP_01405 9.72e-192 nodB1 - - G - - - deacetylase
HGDKEKEP_01406 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HGDKEKEP_01407 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HGDKEKEP_01408 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
HGDKEKEP_01409 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGDKEKEP_01410 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGDKEKEP_01411 1.29e-140 yheG - - GM - - - NAD(P)H-binding
HGDKEKEP_01412 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HGDKEKEP_01413 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HGDKEKEP_01414 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HGDKEKEP_01415 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
HGDKEKEP_01416 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
HGDKEKEP_01417 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HGDKEKEP_01418 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
HGDKEKEP_01419 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
HGDKEKEP_01420 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HGDKEKEP_01421 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HGDKEKEP_01422 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HGDKEKEP_01423 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HGDKEKEP_01425 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
HGDKEKEP_01426 1.89e-35 - - - S - - - YhzD-like protein
HGDKEKEP_01427 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_01428 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HGDKEKEP_01429 8.42e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HGDKEKEP_01430 0.0 yhaN - - L - - - AAA domain
HGDKEKEP_01431 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HGDKEKEP_01432 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HGDKEKEP_01433 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGDKEKEP_01434 5.71e-116 yhaK - - S - - - Putative zincin peptidase
HGDKEKEP_01435 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
HGDKEKEP_01436 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HGDKEKEP_01437 1.74e-54 yhaH - - S - - - YtxH-like protein
HGDKEKEP_01438 3.36e-30 - - - - - - - -
HGDKEKEP_01439 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
HGDKEKEP_01440 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HGDKEKEP_01441 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HGDKEKEP_01442 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HGDKEKEP_01443 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HGDKEKEP_01444 2.89e-161 ecsC - - S - - - EcsC protein family
HGDKEKEP_01445 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HGDKEKEP_01446 2.7e-312 yhfA - - C - - - membrane
HGDKEKEP_01447 1e-44 - - - C - - - Rubrerythrin
HGDKEKEP_01448 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HGDKEKEP_01449 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGDKEKEP_01450 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HGDKEKEP_01451 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HGDKEKEP_01452 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HGDKEKEP_01453 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01454 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HGDKEKEP_01455 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGDKEKEP_01456 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HGDKEKEP_01457 1.55e-252 yhfE - - G - - - peptidase M42
HGDKEKEP_01458 1.79e-92 - - - S - - - ASCH
HGDKEKEP_01459 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGDKEKEP_01460 1.63e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HGDKEKEP_01461 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HGDKEKEP_01462 1.01e-141 yhfK - - GM - - - NmrA-like family
HGDKEKEP_01463 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HGDKEKEP_01464 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HGDKEKEP_01465 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGDKEKEP_01466 5.62e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HGDKEKEP_01467 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HGDKEKEP_01468 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HGDKEKEP_01469 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HGDKEKEP_01470 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGDKEKEP_01471 1.74e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HGDKEKEP_01472 1.16e-133 yngC - - S - - - membrane-associated protein
HGDKEKEP_01473 1.07e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HGDKEKEP_01474 1.36e-100 yngA - - S - - - membrane
HGDKEKEP_01475 8.44e-31 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HGDKEKEP_01476 5.7e-309 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HGDKEKEP_01477 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HGDKEKEP_01479 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HGDKEKEP_01480 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HGDKEKEP_01481 8.74e-75 ynfC - - - - - - -
HGDKEKEP_01482 1.82e-18 - - - - - - - -
HGDKEKEP_01483 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGDKEKEP_01484 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGDKEKEP_01485 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HGDKEKEP_01486 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGDKEKEP_01487 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HGDKEKEP_01488 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HGDKEKEP_01489 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HGDKEKEP_01490 7.38e-121 yobW - - - - - - -
HGDKEKEP_01491 1.73e-221 yobV - - K - - - WYL domain
HGDKEKEP_01492 4.8e-111 - - - K - - - Bacterial transcription activator, effector binding domain
HGDKEKEP_01493 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGDKEKEP_01494 6.23e-127 yobS - - K - - - Transcriptional regulator
HGDKEKEP_01495 2.81e-178 - - - J - - - FR47-like protein
HGDKEKEP_01496 5.45e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HGDKEKEP_01497 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HGDKEKEP_01498 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HGDKEKEP_01499 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
HGDKEKEP_01500 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGDKEKEP_01501 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HGDKEKEP_01502 3.18e-101 - - - S - - - SMI1-KNR4 cell-wall
HGDKEKEP_01503 7.01e-129 yokK - - S - - - SMI1 / KNR4 family
HGDKEKEP_01504 1.06e-127 - - - J - - - Acetyltransferase (GNAT) domain
HGDKEKEP_01507 2.34e-14 - - - S - - - YolD-like protein
HGDKEKEP_01508 4.84e-85 - - - S - - - damaged DNA binding
HGDKEKEP_01509 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGDKEKEP_01510 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGDKEKEP_01512 6.48e-288 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HGDKEKEP_01513 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HGDKEKEP_01514 9.34e-176 azlC - - E - - - AzlC protein
HGDKEKEP_01515 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
HGDKEKEP_01516 2.76e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HGDKEKEP_01517 1.74e-131 yrdC - - Q - - - Isochorismatase family
HGDKEKEP_01518 3.24e-75 - - - S - - - Protein of unknown function (DUF2568)
HGDKEKEP_01519 2.01e-118 yrdA - - S - - - DinB family
HGDKEKEP_01520 3.9e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HGDKEKEP_01521 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HGDKEKEP_01522 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HGDKEKEP_01523 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
HGDKEKEP_01525 4.22e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HGDKEKEP_01526 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_01527 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
HGDKEKEP_01528 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HGDKEKEP_01529 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_01530 1.19e-191 - - - S - - - Alpha beta hydrolase
HGDKEKEP_01531 6.61e-80 - - - T - - - sh3 domain protein
HGDKEKEP_01532 2.06e-81 - - - T - - - sh3 domain protein
HGDKEKEP_01533 6.62e-87 - - - E - - - Glyoxalase-like domain
HGDKEKEP_01534 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HGDKEKEP_01535 9.61e-84 yraF - - M - - - Spore coat protein
HGDKEKEP_01536 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HGDKEKEP_01537 6.11e-36 yraE - - - ko:K06440 - ko00000 -
HGDKEKEP_01538 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HGDKEKEP_01539 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HGDKEKEP_01540 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HGDKEKEP_01541 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HGDKEKEP_01542 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HGDKEKEP_01543 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HGDKEKEP_01544 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HGDKEKEP_01545 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HGDKEKEP_01546 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HGDKEKEP_01547 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HGDKEKEP_01548 0.0 levR - - K - - - PTS system fructose IIA component
HGDKEKEP_01549 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_01550 5.63e-137 yrhP - - E - - - LysE type translocator
HGDKEKEP_01551 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HGDKEKEP_01552 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_01553 3.51e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
HGDKEKEP_01554 2.18e-84 oatA - - I - - - Acyltransferase family
HGDKEKEP_01555 0.0 oatA - - I - - - Acyltransferase family
HGDKEKEP_01556 2.58e-58 yrhK - - S - - - YrhK-like protein
HGDKEKEP_01557 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HGDKEKEP_01558 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HGDKEKEP_01559 4.3e-124 yrhH - - Q - - - methyltransferase
HGDKEKEP_01560 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HGDKEKEP_01561 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HGDKEKEP_01563 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HGDKEKEP_01564 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HGDKEKEP_01565 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
HGDKEKEP_01566 5.71e-48 yrhC - - S - - - YrhC-like protein
HGDKEKEP_01567 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HGDKEKEP_01568 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HGDKEKEP_01569 3.26e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGDKEKEP_01570 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HGDKEKEP_01571 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HGDKEKEP_01572 2.02e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
HGDKEKEP_01573 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HGDKEKEP_01574 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGDKEKEP_01575 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HGDKEKEP_01576 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HGDKEKEP_01577 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HGDKEKEP_01578 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HGDKEKEP_01579 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HGDKEKEP_01580 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HGDKEKEP_01581 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGDKEKEP_01582 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HGDKEKEP_01583 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGDKEKEP_01584 1.25e-241 yrrI - - S - - - AI-2E family transporter
HGDKEKEP_01585 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGDKEKEP_01586 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGDKEKEP_01587 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_01588 1.54e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_01591 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
HGDKEKEP_01592 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HGDKEKEP_01593 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGDKEKEP_01594 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGDKEKEP_01595 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HGDKEKEP_01596 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HGDKEKEP_01597 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGDKEKEP_01598 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGDKEKEP_01599 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGDKEKEP_01600 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_01601 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_01602 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HGDKEKEP_01603 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
HGDKEKEP_01604 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HGDKEKEP_01605 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
HGDKEKEP_01607 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HGDKEKEP_01608 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HGDKEKEP_01609 4.28e-163 - - - - - - - -
HGDKEKEP_01610 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGDKEKEP_01611 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
HGDKEKEP_01612 1.24e-156 ydhC - - K - - - FCD
HGDKEKEP_01613 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HGDKEKEP_01614 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HGDKEKEP_01615 1.9e-89 - - - K - - - Winged helix DNA-binding domain
HGDKEKEP_01616 6.42e-147 ydgI - - C - - - nitroreductase
HGDKEKEP_01617 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HGDKEKEP_01618 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGDKEKEP_01619 6.94e-117 - - - S - - - DinB family
HGDKEKEP_01620 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_01621 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HGDKEKEP_01622 8.04e-111 yycN - - K - - - Acetyltransferase
HGDKEKEP_01623 5.76e-70 - - - S - - - DoxX-like family
HGDKEKEP_01624 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HGDKEKEP_01625 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HGDKEKEP_01626 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HGDKEKEP_01627 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGDKEKEP_01628 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_01629 5e-152 ydfR - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_01631 3.75e-39 - - - - - - - -
HGDKEKEP_01632 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HGDKEKEP_01633 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HGDKEKEP_01635 5.36e-203 ybaS - - S - - - Na -dependent transporter
HGDKEKEP_01636 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
HGDKEKEP_01637 1.43e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_01638 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_01639 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HGDKEKEP_01640 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HGDKEKEP_01641 6.63e-270 ybbC - - S - - - protein conserved in bacteria
HGDKEKEP_01642 8.03e-21 ybbC - - S - - - protein conserved in bacteria
HGDKEKEP_01643 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HGDKEKEP_01644 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HGDKEKEP_01645 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_01646 3.14e-193 ybbH - - K - - - transcriptional
HGDKEKEP_01647 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGDKEKEP_01648 8.99e-114 ybbJ - - J - - - acetyltransferase
HGDKEKEP_01649 9.88e-100 ybbK - - S - - - Protein of unknown function (DUF523)
HGDKEKEP_01655 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_01656 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HGDKEKEP_01657 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGDKEKEP_01658 3.55e-291 ybbR - - S - - - protein conserved in bacteria
HGDKEKEP_01659 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGDKEKEP_01660 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGDKEKEP_01679 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HGDKEKEP_01680 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HGDKEKEP_01681 1.19e-258 yaaN - - P - - - Belongs to the TelA family
HGDKEKEP_01682 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HGDKEKEP_01683 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGDKEKEP_01684 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HGDKEKEP_01685 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HGDKEKEP_01686 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HGDKEKEP_01687 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HGDKEKEP_01688 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HGDKEKEP_01689 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HGDKEKEP_01690 2.84e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HGDKEKEP_01691 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGDKEKEP_01692 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HGDKEKEP_01693 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGDKEKEP_01694 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HGDKEKEP_01695 1.18e-277 yabE - - T - - - protein conserved in bacteria
HGDKEKEP_01696 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGDKEKEP_01697 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGDKEKEP_01698 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HGDKEKEP_01699 5.32e-53 veg - - S - - - protein conserved in bacteria
HGDKEKEP_01700 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HGDKEKEP_01701 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGDKEKEP_01702 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HGDKEKEP_01703 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HGDKEKEP_01704 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HGDKEKEP_01705 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGDKEKEP_01706 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGDKEKEP_01707 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGDKEKEP_01708 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGDKEKEP_01709 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HGDKEKEP_01710 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGDKEKEP_01711 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HGDKEKEP_01712 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_01713 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HGDKEKEP_01714 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HGDKEKEP_01715 1.91e-66 yabP - - S - - - Sporulation protein YabP
HGDKEKEP_01716 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
HGDKEKEP_01717 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HGDKEKEP_01718 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HGDKEKEP_01721 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HGDKEKEP_01722 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HGDKEKEP_01723 6.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HGDKEKEP_01724 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGDKEKEP_01725 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HGDKEKEP_01726 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGDKEKEP_01727 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGDKEKEP_01728 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGDKEKEP_01729 2.41e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HGDKEKEP_01730 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HGDKEKEP_01731 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HGDKEKEP_01732 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HGDKEKEP_01733 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HGDKEKEP_01734 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HGDKEKEP_01735 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HGDKEKEP_01736 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HGDKEKEP_01737 1.55e-170 kipR - - K - - - Transcriptional regulator
HGDKEKEP_01738 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HGDKEKEP_01740 8.97e-65 yczJ - - S - - - biosynthesis
HGDKEKEP_01741 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HGDKEKEP_01742 8.6e-220 ycsN - - S - - - Oxidoreductase
HGDKEKEP_01743 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HGDKEKEP_01744 0.0 ydaB - - IQ - - - acyl-CoA ligase
HGDKEKEP_01745 1e-127 ydaC - - Q - - - Methyltransferase domain
HGDKEKEP_01746 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_01747 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HGDKEKEP_01748 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGDKEKEP_01749 6.13e-100 ydaG - - S - - - general stress protein
HGDKEKEP_01750 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HGDKEKEP_01751 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HGDKEKEP_01752 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HGDKEKEP_01753 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGDKEKEP_01754 5.12e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HGDKEKEP_01755 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HGDKEKEP_01756 1.84e-34 - - - - - - - -
HGDKEKEP_01757 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
HGDKEKEP_01759 6.14e-53 - - - - - - - -
HGDKEKEP_01760 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HGDKEKEP_01761 1.67e-42 ydaS - - S - - - membrane
HGDKEKEP_01762 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HGDKEKEP_01763 4.3e-190 ydbA - - P - - - EcsC protein family
HGDKEKEP_01764 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HGDKEKEP_01765 2.17e-78 ydbB - - G - - - Cupin domain
HGDKEKEP_01766 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
HGDKEKEP_01767 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HGDKEKEP_01768 4.99e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HGDKEKEP_01769 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGDKEKEP_01770 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HGDKEKEP_01771 7.33e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGDKEKEP_01772 1.32e-230 ydbI - - S - - - AI-2E family transporter
HGDKEKEP_01773 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_01774 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGDKEKEP_01775 9.32e-70 ydbL - - - - - - -
HGDKEKEP_01776 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
HGDKEKEP_01777 1.49e-26 - - - S - - - Fur-regulated basic protein B
HGDKEKEP_01779 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGDKEKEP_01780 4.19e-75 ydbP - - CO - - - Thioredoxin
HGDKEKEP_01781 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HGDKEKEP_01782 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGDKEKEP_01783 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGDKEKEP_01784 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HGDKEKEP_01785 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HGDKEKEP_01786 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HGDKEKEP_01787 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGDKEKEP_01788 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HGDKEKEP_01789 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGDKEKEP_01790 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HGDKEKEP_01791 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HGDKEKEP_01792 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HGDKEKEP_01793 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HGDKEKEP_01794 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HGDKEKEP_01795 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HGDKEKEP_01796 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HGDKEKEP_01797 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HGDKEKEP_01798 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_01799 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HGDKEKEP_01800 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HGDKEKEP_01801 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HGDKEKEP_01809 4.46e-153 - - - E - - - amino acid
HGDKEKEP_01810 9.13e-135 ywqM - - K - - - Transcriptional regulator
HGDKEKEP_01811 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
HGDKEKEP_01812 9.99e-59 - - - - - - - -
HGDKEKEP_01813 5.9e-171 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGDKEKEP_01814 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HGDKEKEP_01815 2.98e-53 - - - - - - - -
HGDKEKEP_01819 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
HGDKEKEP_01820 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HGDKEKEP_01821 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HGDKEKEP_01822 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HGDKEKEP_01823 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HGDKEKEP_01824 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HGDKEKEP_01825 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HGDKEKEP_01826 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HGDKEKEP_01827 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGDKEKEP_01828 4.78e-95 ytkA - - S - - - YtkA-like
HGDKEKEP_01830 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HGDKEKEP_01831 1.52e-79 ytkC - - S - - - Bacteriophage holin family
HGDKEKEP_01832 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HGDKEKEP_01833 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HGDKEKEP_01834 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGDKEKEP_01835 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HGDKEKEP_01836 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HGDKEKEP_01837 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HGDKEKEP_01838 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HGDKEKEP_01839 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGDKEKEP_01840 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HGDKEKEP_01841 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_01842 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGDKEKEP_01843 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HGDKEKEP_01844 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HGDKEKEP_01845 2.75e-136 ytqB - - J - - - Putative rRNA methylase
HGDKEKEP_01846 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HGDKEKEP_01847 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HGDKEKEP_01849 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HGDKEKEP_01850 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_01851 4.46e-211 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_01852 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HGDKEKEP_01853 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_01854 3.99e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGDKEKEP_01855 2.23e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_01856 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HGDKEKEP_01857 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_01858 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HGDKEKEP_01859 5.71e-41 yttA - - S - - - Pfam Transposase IS66
HGDKEKEP_01860 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
HGDKEKEP_01861 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HGDKEKEP_01862 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HGDKEKEP_01863 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HGDKEKEP_01864 1.22e-68 ytwF - - P - - - Sulfurtransferase
HGDKEKEP_01865 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HGDKEKEP_01866 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HGDKEKEP_01867 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_01868 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGDKEKEP_01869 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_01870 4.8e-221 - - - S - - - Acetyl xylan esterase (AXE1)
HGDKEKEP_01871 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HGDKEKEP_01872 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HGDKEKEP_01873 4.1e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HGDKEKEP_01874 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGDKEKEP_01875 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGDKEKEP_01876 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGDKEKEP_01877 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HGDKEKEP_01878 1.19e-190 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HGDKEKEP_01879 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HGDKEKEP_01880 1.13e-165 ytdP - - K - - - Transcriptional regulator
HGDKEKEP_01881 2.13e-75 ytdP - - K - - - Transcriptional regulator
HGDKEKEP_01882 1.36e-202 ytdP - - K - - - Transcriptional regulator
HGDKEKEP_01883 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HGDKEKEP_01884 8.3e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HGDKEKEP_01885 9.64e-94 yteS - - G - - - transport
HGDKEKEP_01886 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HGDKEKEP_01888 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HGDKEKEP_01889 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HGDKEKEP_01890 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HGDKEKEP_01891 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_01892 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HGDKEKEP_01893 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HGDKEKEP_01894 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HGDKEKEP_01895 1.12e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HGDKEKEP_01896 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HGDKEKEP_01897 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HGDKEKEP_01898 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HGDKEKEP_01899 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HGDKEKEP_01900 9.92e-212 ytlQ - - - - - - -
HGDKEKEP_01901 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HGDKEKEP_01902 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HGDKEKEP_01903 3.02e-192 ytmP - - M - - - Phosphotransferase
HGDKEKEP_01904 9.51e-61 ytzH - - S - - - YtzH-like protein
HGDKEKEP_01905 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGDKEKEP_01906 3.05e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGDKEKEP_01907 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HGDKEKEP_01908 1.17e-67 ytzB - - S - - - small secreted protein
HGDKEKEP_01909 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HGDKEKEP_01910 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HGDKEKEP_01911 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HGDKEKEP_01912 3.17e-75 ytpP - - CO - - - Thioredoxin
HGDKEKEP_01913 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HGDKEKEP_01914 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGDKEKEP_01915 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HGDKEKEP_01916 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HGDKEKEP_01917 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGDKEKEP_01918 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HGDKEKEP_01919 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HGDKEKEP_01920 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HGDKEKEP_01921 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HGDKEKEP_01922 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HGDKEKEP_01923 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HGDKEKEP_01924 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HGDKEKEP_01925 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HGDKEKEP_01926 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HGDKEKEP_01927 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGDKEKEP_01928 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGDKEKEP_01930 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGDKEKEP_01931 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HGDKEKEP_01932 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HGDKEKEP_01933 9.83e-141 yttP - - K - - - Transcriptional regulator
HGDKEKEP_01934 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HGDKEKEP_01935 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGDKEKEP_01936 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HGDKEKEP_01937 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGDKEKEP_01938 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGDKEKEP_01939 5.88e-38 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HGDKEKEP_01940 1.7e-73 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGDKEKEP_01941 7.21e-262 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HGDKEKEP_01942 0.0 ytcJ - - S - - - amidohydrolase
HGDKEKEP_01943 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HGDKEKEP_01944 1.11e-41 - - - - - - - -
HGDKEKEP_01945 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HGDKEKEP_01946 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HGDKEKEP_01948 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HGDKEKEP_01950 5.25e-113 yjgD - - S - - - Protein of unknown function (DUF1641)
HGDKEKEP_01951 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HGDKEKEP_01952 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
HGDKEKEP_01953 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HGDKEKEP_01954 3.15e-136 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HGDKEKEP_01955 1.93e-62 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HGDKEKEP_01956 1.13e-29 yjfB - - S - - - Putative motility protein
HGDKEKEP_01957 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
HGDKEKEP_01958 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HGDKEKEP_01960 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGDKEKEP_01961 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
HGDKEKEP_01962 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HGDKEKEP_01963 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGDKEKEP_01965 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HGDKEKEP_01966 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HGDKEKEP_01968 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HGDKEKEP_01969 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HGDKEKEP_01970 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HGDKEKEP_01971 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HGDKEKEP_01972 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HGDKEKEP_01973 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HGDKEKEP_01974 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HGDKEKEP_01975 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HGDKEKEP_01976 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGDKEKEP_01977 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HGDKEKEP_01978 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
HGDKEKEP_01979 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGDKEKEP_01980 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HGDKEKEP_01981 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
HGDKEKEP_01982 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGDKEKEP_01983 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGDKEKEP_01984 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGDKEKEP_01985 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGDKEKEP_01986 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HGDKEKEP_01988 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HGDKEKEP_01989 3.45e-137 bdbD - - O - - - Thioredoxin
HGDKEKEP_01990 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HGDKEKEP_01991 6.7e-139 yvgT - - S - - - membrane
HGDKEKEP_01993 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGDKEKEP_01994 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGDKEKEP_01995 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HGDKEKEP_01996 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HGDKEKEP_01997 9.32e-112 yvgO - - - - - - -
HGDKEKEP_01998 6.19e-201 yvgN - - S - - - reductase
HGDKEKEP_01999 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HGDKEKEP_02000 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HGDKEKEP_02001 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HGDKEKEP_02002 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HGDKEKEP_02003 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HGDKEKEP_02004 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HGDKEKEP_02005 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HGDKEKEP_02007 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_02008 4.04e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_02009 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_02010 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HGDKEKEP_02011 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HGDKEKEP_02012 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_02013 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGDKEKEP_02014 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HGDKEKEP_02015 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HGDKEKEP_02016 3.46e-26 - - - S - - - YvrJ protein family
HGDKEKEP_02017 1.12e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HGDKEKEP_02018 5.07e-32 - - - - - - - -
HGDKEKEP_02019 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_02020 0.0 yvrG - - T - - - Histidine kinase
HGDKEKEP_02021 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HGDKEKEP_02022 2.89e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_02023 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HGDKEKEP_02024 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_02025 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HGDKEKEP_02026 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HGDKEKEP_02027 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_02028 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HGDKEKEP_02029 2.85e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HGDKEKEP_02030 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HGDKEKEP_02031 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HGDKEKEP_02032 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_02033 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_02034 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HGDKEKEP_02035 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HGDKEKEP_02036 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGDKEKEP_02037 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
HGDKEKEP_02038 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGDKEKEP_02039 3.06e-204 yuxN - - K - - - Transcriptional regulator
HGDKEKEP_02040 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_02041 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_02042 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGDKEKEP_02043 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
HGDKEKEP_02044 8.93e-38 ykwD - - J - - - protein with SCP PR1 domains
HGDKEKEP_02046 9.72e-112 yqaS - - L - - - DNA packaging
HGDKEKEP_02047 2.19e-234 - - - S - - - Terminase-like family
HGDKEKEP_02048 2.27e-195 - - - S - - - Phage portal protein, SPP1 Gp6-like
HGDKEKEP_02049 3.28e-79 - - - S - - - Domain of unknown function (DUF4355)
HGDKEKEP_02050 8.27e-157 - - - S - - - Phage capsid family
HGDKEKEP_02052 2.67e-40 - - - S - - - Phage Mu protein F like protein
HGDKEKEP_02054 8.09e-60 - - - - - - - -
HGDKEKEP_02056 7.25e-41 - - - - - - - -
HGDKEKEP_02057 2.37e-128 - - - S - - - Protein of unknown function (DUF3383)
HGDKEKEP_02058 8.46e-46 - - - - - - - -
HGDKEKEP_02059 2.87e-19 - - - - - - - -
HGDKEKEP_02060 1.7e-160 - - - N - - - phage tail tape measure protein
HGDKEKEP_02061 6.22e-47 - - - M - - - LysM domain
HGDKEKEP_02062 1.13e-41 - - - - - - - -
HGDKEKEP_02063 3.69e-111 - - - - - - - -
HGDKEKEP_02065 6.43e-30 - - - S - - - Protein of unknown function (DUF2634)
HGDKEKEP_02066 1.84e-130 - - - S - - - homolog of phage Mu protein gp47
HGDKEKEP_02067 1.22e-78 - - - - - - - -
HGDKEKEP_02068 2.68e-22 - - - - - - - -
HGDKEKEP_02069 4.39e-12 - - - - - - - -
HGDKEKEP_02071 4.24e-122 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
HGDKEKEP_02072 7.72e-37 xhlA - - S - - - Haemolysin XhlA
HGDKEKEP_02073 1.25e-38 xhlB - - S - - - SPP1 phage holin
HGDKEKEP_02074 4.12e-158 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGDKEKEP_02076 1.31e-70 - - - - - - - -
HGDKEKEP_02077 1.06e-60 - - - S - - - YolD-like protein
HGDKEKEP_02078 3.74e-206 - - - L - - - Recombinase
HGDKEKEP_02079 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HGDKEKEP_02080 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
HGDKEKEP_02081 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HGDKEKEP_02082 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HGDKEKEP_02083 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_02084 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_02085 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_02086 4.15e-14 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_02087 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGDKEKEP_02088 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HGDKEKEP_02089 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HGDKEKEP_02090 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGDKEKEP_02091 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HGDKEKEP_02092 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HGDKEKEP_02093 1.27e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HGDKEKEP_02094 2e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HGDKEKEP_02095 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HGDKEKEP_02096 2.19e-153 yxaC - - M - - - effector of murein hydrolase
HGDKEKEP_02097 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HGDKEKEP_02098 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGDKEKEP_02099 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_02100 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HGDKEKEP_02101 5.18e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HGDKEKEP_02102 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HGDKEKEP_02103 1.35e-97 yxaI - - S - - - membrane protein domain
HGDKEKEP_02104 7.97e-83 - - - S - - - Family of unknown function (DUF5391)
HGDKEKEP_02105 2.54e-43 yxaI - - S - - - membrane protein domain
HGDKEKEP_02106 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGDKEKEP_02107 6.97e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
HGDKEKEP_02108 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGDKEKEP_02109 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGDKEKEP_02111 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HGDKEKEP_02112 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_02113 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_02114 1.05e-101 - - - T - - - HPP family
HGDKEKEP_02115 2.23e-17 - - - S - - - CGNR zinc finger
HGDKEKEP_02117 7.27e-55 - - - - - - - -
HGDKEKEP_02118 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HGDKEKEP_02119 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGDKEKEP_02120 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGDKEKEP_02121 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HGDKEKEP_02122 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HGDKEKEP_02123 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HGDKEKEP_02124 4.99e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HGDKEKEP_02125 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HGDKEKEP_02126 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HGDKEKEP_02127 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HGDKEKEP_02128 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HGDKEKEP_02129 3.3e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HGDKEKEP_02130 9.37e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_02131 1.75e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_02132 8.64e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_02133 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HGDKEKEP_02134 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HGDKEKEP_02135 1.55e-215 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HGDKEKEP_02136 9.65e-91 - - - - - - - -
HGDKEKEP_02137 7.57e-28 yxeD - - - - - - -
HGDKEKEP_02138 5.99e-41 yxeE - - - - - - -
HGDKEKEP_02141 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
HGDKEKEP_02142 4.03e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HGDKEKEP_02143 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGDKEKEP_02144 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGDKEKEP_02145 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGDKEKEP_02146 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGDKEKEP_02147 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_02148 4.78e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HGDKEKEP_02149 0.0 yxeQ - - S - - - MmgE/PrpD family
HGDKEKEP_02150 2.99e-249 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HGDKEKEP_02151 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
HGDKEKEP_02152 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HGDKEKEP_02153 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGDKEKEP_02154 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGDKEKEP_02155 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HGDKEKEP_02156 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGDKEKEP_02157 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HGDKEKEP_02158 1.49e-308 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HGDKEKEP_02159 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
HGDKEKEP_02160 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HGDKEKEP_02161 0.0 - - - L - - - HKD family nuclease
HGDKEKEP_02162 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
HGDKEKEP_02163 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
HGDKEKEP_02164 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HGDKEKEP_02165 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HGDKEKEP_02166 1.56e-53 - - - - - - - -
HGDKEKEP_02167 8.86e-317 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGDKEKEP_02168 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HGDKEKEP_02169 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
HGDKEKEP_02170 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_02171 5.69e-208 yxxF - - EG - - - EamA-like transporter family
HGDKEKEP_02172 0.0 wapA - - M - - - COG3209 Rhs family protein
HGDKEKEP_02173 3.29e-19 yxiJ - - S - - - YxiJ-like protein
HGDKEKEP_02174 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
HGDKEKEP_02175 1.27e-69 - - - - - - - -
HGDKEKEP_02177 5.06e-175 - - - - - - - -
HGDKEKEP_02178 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
HGDKEKEP_02179 7.13e-100 - - - - - - - -
HGDKEKEP_02180 4.48e-58 - - - - - - - -
HGDKEKEP_02181 4.67e-89 yxiG - - - - - - -
HGDKEKEP_02182 9.7e-68 yxxG - - - - - - -
HGDKEKEP_02183 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
HGDKEKEP_02186 3.42e-173 - - - - - - - -
HGDKEKEP_02187 8.21e-50 yxiI - - S - - - Protein of unknown function (DUF2716)
HGDKEKEP_02188 1.86e-40 - - - - - - - -
HGDKEKEP_02191 4.06e-58 yxiJ - - S - - - YxiJ-like protein
HGDKEKEP_02194 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGDKEKEP_02195 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HGDKEKEP_02196 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HGDKEKEP_02197 7.23e-141 - - - - - - - -
HGDKEKEP_02198 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGDKEKEP_02199 7.21e-183 bglS - - M - - - licheninase activity
HGDKEKEP_02200 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HGDKEKEP_02201 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGDKEKEP_02202 2.28e-63 yxiS - - - - - - -
HGDKEKEP_02203 1.51e-91 - - - T - - - Domain of unknown function (DUF4163)
HGDKEKEP_02204 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HGDKEKEP_02205 9.07e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HGDKEKEP_02206 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HGDKEKEP_02207 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HGDKEKEP_02208 1.69e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGDKEKEP_02209 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HGDKEKEP_02210 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HGDKEKEP_02211 2.13e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HGDKEKEP_02212 2.88e-111 yxjI - - S - - - LURP-one-related
HGDKEKEP_02214 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HGDKEKEP_02215 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HGDKEKEP_02216 8.24e-73 - - - T - - - Signal transduction histidine kinase
HGDKEKEP_02217 1.76e-166 - - - T - - - Signal transduction histidine kinase
HGDKEKEP_02218 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
HGDKEKEP_02219 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HGDKEKEP_02220 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGDKEKEP_02221 2.46e-67 - - - - - - - -
HGDKEKEP_02222 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HGDKEKEP_02223 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HGDKEKEP_02224 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HGDKEKEP_02225 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HGDKEKEP_02226 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGDKEKEP_02227 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HGDKEKEP_02228 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HGDKEKEP_02229 6.92e-92 yviE - - - - - - -
HGDKEKEP_02230 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HGDKEKEP_02231 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HGDKEKEP_02232 7.06e-102 yvyG - - NOU - - - FlgN protein
HGDKEKEP_02233 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HGDKEKEP_02234 1.06e-95 yvyF - - S - - - flagellar protein
HGDKEKEP_02235 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HGDKEKEP_02236 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HGDKEKEP_02237 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HGDKEKEP_02238 1.24e-198 degV - - S - - - protein conserved in bacteria
HGDKEKEP_02239 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_02240 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HGDKEKEP_02241 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HGDKEKEP_02242 1.23e-151 - - - K - - - Transcriptional regulator
HGDKEKEP_02246 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
HGDKEKEP_02249 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_02251 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HGDKEKEP_02252 2.91e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HGDKEKEP_02253 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HGDKEKEP_02254 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HGDKEKEP_02255 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HGDKEKEP_02257 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGDKEKEP_02258 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HGDKEKEP_02259 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_02260 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HGDKEKEP_02261 5.89e-230 yaaC - - S - - - YaaC-like Protein
HGDKEKEP_02262 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HGDKEKEP_02263 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGDKEKEP_02264 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HGDKEKEP_02265 5.55e-137 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HGDKEKEP_02266 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGDKEKEP_02268 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HGDKEKEP_02269 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HGDKEKEP_02270 7.55e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HGDKEKEP_02271 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HGDKEKEP_02272 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGDKEKEP_02273 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGDKEKEP_02274 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGDKEKEP_02275 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGDKEKEP_02276 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HGDKEKEP_02277 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HGDKEKEP_02278 5.93e-85 hxlR - - K - - - transcriptional
HGDKEKEP_02279 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HGDKEKEP_02280 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HGDKEKEP_02281 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_02282 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HGDKEKEP_02283 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
HGDKEKEP_02284 3.36e-91 nin - - S - - - Competence protein J (ComJ)
HGDKEKEP_02285 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HGDKEKEP_02286 8.9e-22 - - - S - - - AAA domain
HGDKEKEP_02287 2.13e-113 - - - S - - - AAA domain
HGDKEKEP_02288 2.49e-27 - - - - - - - -
HGDKEKEP_02289 1.06e-57 - - - K - - - MarR family
HGDKEKEP_02290 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
HGDKEKEP_02291 1.11e-96 yckC - - S - - - membrane
HGDKEKEP_02294 8.47e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HGDKEKEP_02295 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGDKEKEP_02296 2.26e-123 yciC - - S - - - GTPases (G3E family)
HGDKEKEP_02297 2.72e-141 yciC - - S - - - GTPases (G3E family)
HGDKEKEP_02298 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
HGDKEKEP_02299 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HGDKEKEP_02300 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HGDKEKEP_02301 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HGDKEKEP_02302 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGDKEKEP_02303 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGDKEKEP_02304 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HGDKEKEP_02305 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HGDKEKEP_02306 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HGDKEKEP_02307 3.3e-200 ycgS - - I - - - alpha/beta hydrolase fold
HGDKEKEP_02308 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HGDKEKEP_02309 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
HGDKEKEP_02310 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HGDKEKEP_02311 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGDKEKEP_02312 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGDKEKEP_02313 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HGDKEKEP_02314 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HGDKEKEP_02315 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HGDKEKEP_02316 5.64e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HGDKEKEP_02317 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
HGDKEKEP_02318 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGDKEKEP_02319 1.31e-140 tmrB - - S - - - AAA domain
HGDKEKEP_02320 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGDKEKEP_02321 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HGDKEKEP_02322 2.67e-154 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_02323 4.4e-134 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_02324 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HGDKEKEP_02325 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HGDKEKEP_02326 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HGDKEKEP_02327 1.31e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HGDKEKEP_02328 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HGDKEKEP_02329 2.72e-105 ycgB - - - - - - -
HGDKEKEP_02330 0.0 ycgA - - S - - - Membrane
HGDKEKEP_02331 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HGDKEKEP_02332 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HGDKEKEP_02333 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HGDKEKEP_02334 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HGDKEKEP_02335 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGDKEKEP_02336 0.0 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
HGDKEKEP_02337 2.19e-86 - - - - ko:K19174 - ko00000,ko02048 -
HGDKEKEP_02338 3.83e-131 - - - V ko:K19173 - ko00000,ko02048 Type I site-specific restriction-modification system, R (Restriction) subunit and related
HGDKEKEP_02339 2.86e-193 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
HGDKEKEP_02340 8.5e-272 - - - EH ko:K19170 - ko00000,ko02048 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
HGDKEKEP_02341 3.14e-187 - - - EL ko:K19171 - ko00000,ko02048 AAA domain
HGDKEKEP_02342 1.9e-41 - - - S - - - DNA sulphur modification protein DndE
HGDKEKEP_02343 8.04e-181 - 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
HGDKEKEP_02344 1.72e-255 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HGDKEKEP_02345 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HGDKEKEP_02346 2.96e-245 yceH - - P - - - Belongs to the TelA family
HGDKEKEP_02347 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HGDKEKEP_02348 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HGDKEKEP_02349 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HGDKEKEP_02350 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HGDKEKEP_02351 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HGDKEKEP_02352 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGDKEKEP_02353 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGDKEKEP_02354 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HGDKEKEP_02355 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HGDKEKEP_02356 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HGDKEKEP_02357 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGDKEKEP_02358 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HGDKEKEP_02359 1.65e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_02360 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HGDKEKEP_02361 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_02362 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_02363 6.38e-229 ycdA - - S - - - Domain of unknown function (DUF5105)
HGDKEKEP_02364 4.58e-68 yccK - - C - - - Aldo keto reductase
HGDKEKEP_02365 2.9e-28 yccK - - C - - - Aldo keto reductase
HGDKEKEP_02366 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_02367 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGDKEKEP_02368 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HGDKEKEP_02369 6.18e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HGDKEKEP_02370 7.13e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
HGDKEKEP_02371 4.32e-78 - - - S - - - RDD family
HGDKEKEP_02372 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGDKEKEP_02373 8.02e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HGDKEKEP_02374 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HGDKEKEP_02375 1.45e-301 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HGDKEKEP_02376 1.39e-258 ycbU - - E - - - Selenocysteine lyase
HGDKEKEP_02377 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGDKEKEP_02378 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGDKEKEP_02379 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGDKEKEP_02380 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HGDKEKEP_02381 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
HGDKEKEP_02382 7.07e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HGDKEKEP_02383 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HGDKEKEP_02385 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGDKEKEP_02386 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_02387 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HGDKEKEP_02388 4.83e-30 ykzE - - - - - - -
HGDKEKEP_02390 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HGDKEKEP_02391 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HGDKEKEP_02392 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
HGDKEKEP_02393 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HGDKEKEP_02394 3.83e-204 rsgI - - S - - - Anti-sigma factor N-terminus
HGDKEKEP_02395 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_02396 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HGDKEKEP_02397 1.71e-143 ykoX - - S - - - membrane-associated protein
HGDKEKEP_02398 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HGDKEKEP_02399 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HGDKEKEP_02400 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HGDKEKEP_02401 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HGDKEKEP_02402 0.0 ykoS - - - - - - -
HGDKEKEP_02403 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HGDKEKEP_02404 2.12e-121 ykoP - - G - - - polysaccharide deacetylase
HGDKEKEP_02405 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HGDKEKEP_02406 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HGDKEKEP_02407 3.04e-36 ykoL - - - - - - -
HGDKEKEP_02408 1.63e-25 - - - - - - - -
HGDKEKEP_02409 1.49e-70 tnrA - - K - - - transcriptional
HGDKEKEP_02410 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HGDKEKEP_02412 1.45e-08 - - - - - - - -
HGDKEKEP_02413 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HGDKEKEP_02414 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
HGDKEKEP_02415 6.05e-307 ykoH - - T - - - Histidine kinase
HGDKEKEP_02416 1.68e-156 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_02417 4.05e-141 ykoF - - S - - - YKOF-related Family
HGDKEKEP_02418 3.99e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HGDKEKEP_02419 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_02420 5.18e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HGDKEKEP_02421 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGDKEKEP_02422 6.07e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGDKEKEP_02423 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGDKEKEP_02424 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HGDKEKEP_02425 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HGDKEKEP_02426 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
HGDKEKEP_02427 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HGDKEKEP_02428 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGDKEKEP_02429 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGDKEKEP_02430 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HGDKEKEP_02431 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HGDKEKEP_02432 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HGDKEKEP_02433 6.97e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGDKEKEP_02434 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
HGDKEKEP_02435 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
HGDKEKEP_02436 9.93e-15 - - - - - - - -
HGDKEKEP_02437 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGDKEKEP_02438 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
HGDKEKEP_02439 9.79e-102 ykgA - - E - - - Amidinotransferase
HGDKEKEP_02440 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HGDKEKEP_02441 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_02442 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HGDKEKEP_02443 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HGDKEKEP_02444 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HGDKEKEP_02446 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGDKEKEP_02447 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_02448 8.28e-222 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_02449 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_02450 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HGDKEKEP_02451 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HGDKEKEP_02452 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGDKEKEP_02454 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGDKEKEP_02455 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGDKEKEP_02456 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGDKEKEP_02457 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
HGDKEKEP_02458 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HGDKEKEP_02459 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HGDKEKEP_02460 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HGDKEKEP_02461 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HGDKEKEP_02462 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HGDKEKEP_02463 1.15e-52 xhlB - - S - - - SPP1 phage holin
HGDKEKEP_02464 2.21e-51 xhlA - - S - - - Haemolysin XhlA
HGDKEKEP_02465 9.79e-195 xepA - - - - - - -
HGDKEKEP_02466 6.35e-31 xkdX - - - - - - -
HGDKEKEP_02467 2.7e-68 xkdW - - S - - - XkdW protein
HGDKEKEP_02468 0.0 - - - - - - - -
HGDKEKEP_02469 4.43e-56 - - - - - - - -
HGDKEKEP_02470 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HGDKEKEP_02471 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HGDKEKEP_02472 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
HGDKEKEP_02473 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
HGDKEKEP_02474 2.31e-232 xkdQ - - G - - - NLP P60 protein
HGDKEKEP_02475 1.73e-151 xkdP - - S - - - Lysin motif
HGDKEKEP_02476 0.0 xkdO - - L - - - Transglycosylase SLT domain
HGDKEKEP_02477 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HGDKEKEP_02478 2.45e-98 xkdM - - S - - - Phage tail tube protein
HGDKEKEP_02479 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HGDKEKEP_02480 2.87e-101 xkdJ - - - - - - -
HGDKEKEP_02481 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGDKEKEP_02482 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HGDKEKEP_02483 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
HGDKEKEP_02484 3.91e-217 xkdG - - S - - - Phage capsid family
HGDKEKEP_02485 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
HGDKEKEP_02486 0.0 yqbA - - S - - - portal protein
HGDKEKEP_02487 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HGDKEKEP_02488 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HGDKEKEP_02489 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HGDKEKEP_02494 8.72e-152 xkdC - - L - - - Bacterial dnaA protein
HGDKEKEP_02495 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
HGDKEKEP_02497 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_02498 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
HGDKEKEP_02499 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HGDKEKEP_02500 1.11e-138 yjqB - - S - - - Pfam:DUF867
HGDKEKEP_02501 1.35e-80 yjqA - - S - - - Bacterial PH domain
HGDKEKEP_02502 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGDKEKEP_02503 1.09e-34 - - - S - - - YCII-related domain
HGDKEKEP_02505 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_02507 8.23e-39 - - - - - - - -
HGDKEKEP_02508 4.78e-32 - - - - - - - -
HGDKEKEP_02509 3.02e-117 - - - L - - - Replication protein
HGDKEKEP_02510 1.02e-27 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HGDKEKEP_02511 9.8e-22 - - - - - - - -
HGDKEKEP_02512 6.22e-224 - - - L - - - Replication protein
HGDKEKEP_02513 1.12e-154 rapE - - S ko:K06363 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HGDKEKEP_02516 6.29e-100 - - - K - - - Transcriptional regulator
HGDKEKEP_02517 9.8e-302 pre - - D - - - plasmid recombination enzyme
HGDKEKEP_02518 3.36e-181 ysnF - - S - - - protein conserved in bacteria
HGDKEKEP_02519 3.28e-46 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HGDKEKEP_02520 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HGDKEKEP_02521 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HGDKEKEP_02522 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGDKEKEP_02523 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGDKEKEP_02524 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HGDKEKEP_02525 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGDKEKEP_02526 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGDKEKEP_02527 2.62e-238 ysoA - - H - - - Tetratricopeptide repeat
HGDKEKEP_02528 5.98e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGDKEKEP_02529 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGDKEKEP_02530 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HGDKEKEP_02531 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGDKEKEP_02532 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HGDKEKEP_02533 4.77e-116 ysxD - - - - - - -
HGDKEKEP_02534 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGDKEKEP_02535 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HGDKEKEP_02536 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGDKEKEP_02537 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HGDKEKEP_02538 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HGDKEKEP_02539 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HGDKEKEP_02540 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HGDKEKEP_02541 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HGDKEKEP_02542 1.53e-35 - - - - - - - -
HGDKEKEP_02543 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGDKEKEP_02544 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HGDKEKEP_02545 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HGDKEKEP_02546 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HGDKEKEP_02547 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HGDKEKEP_02548 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HGDKEKEP_02549 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HGDKEKEP_02550 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HGDKEKEP_02551 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HGDKEKEP_02552 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HGDKEKEP_02553 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HGDKEKEP_02554 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HGDKEKEP_02555 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HGDKEKEP_02556 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HGDKEKEP_02557 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HGDKEKEP_02558 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HGDKEKEP_02559 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HGDKEKEP_02560 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGDKEKEP_02561 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HGDKEKEP_02562 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HGDKEKEP_02563 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HGDKEKEP_02564 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGDKEKEP_02565 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HGDKEKEP_02566 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HGDKEKEP_02567 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGDKEKEP_02568 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HGDKEKEP_02569 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGDKEKEP_02570 3.51e-164 yebC - - K - - - transcriptional regulatory protein
HGDKEKEP_02571 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HGDKEKEP_02573 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
HGDKEKEP_02575 1.91e-151 yrzF - - T - - - serine threonine protein kinase
HGDKEKEP_02576 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HGDKEKEP_02577 0.0 csbX - - EGP - - - the major facilitator superfamily
HGDKEKEP_02578 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HGDKEKEP_02579 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGDKEKEP_02580 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGDKEKEP_02581 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HGDKEKEP_02582 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGDKEKEP_02583 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGDKEKEP_02584 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HGDKEKEP_02585 2.16e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
HGDKEKEP_02586 8.64e-145 yrbG - - S - - - membrane
HGDKEKEP_02587 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HGDKEKEP_02588 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
HGDKEKEP_02589 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGDKEKEP_02590 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HGDKEKEP_02591 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HGDKEKEP_02592 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HGDKEKEP_02593 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGDKEKEP_02594 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGDKEKEP_02595 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGDKEKEP_02596 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HGDKEKEP_02598 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HGDKEKEP_02599 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGDKEKEP_02600 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HGDKEKEP_02601 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HGDKEKEP_02602 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_02603 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HGDKEKEP_02604 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGDKEKEP_02605 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HGDKEKEP_02606 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGDKEKEP_02607 2.79e-105 yrrD - - S - - - protein conserved in bacteria
HGDKEKEP_02608 8.4e-42 yrzR - - - - - - -
HGDKEKEP_02609 8.96e-11 - - - S - - - Protein of unknown function (DUF3918)
HGDKEKEP_02610 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGDKEKEP_02611 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HGDKEKEP_02612 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
HGDKEKEP_02613 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HGDKEKEP_02614 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGDKEKEP_02615 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGDKEKEP_02616 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HGDKEKEP_02617 3.58e-51 ylmC - - S - - - sporulation protein
HGDKEKEP_02618 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HGDKEKEP_02619 6.37e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HGDKEKEP_02620 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_02621 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_02622 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HGDKEKEP_02624 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HGDKEKEP_02625 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGDKEKEP_02626 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGDKEKEP_02627 5.37e-76 sbp - - S - - - small basic protein
HGDKEKEP_02628 8.67e-132 ylxX - - S - - - protein conserved in bacteria
HGDKEKEP_02629 1.35e-143 ylxW - - S - - - protein conserved in bacteria
HGDKEKEP_02630 2.77e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGDKEKEP_02631 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HGDKEKEP_02632 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGDKEKEP_02633 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HGDKEKEP_02634 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGDKEKEP_02635 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGDKEKEP_02636 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGDKEKEP_02637 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HGDKEKEP_02638 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HGDKEKEP_02639 3.42e-68 ftsL - - D - - - Essential cell division protein
HGDKEKEP_02640 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGDKEKEP_02641 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HGDKEKEP_02642 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HGDKEKEP_02643 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGDKEKEP_02644 1.33e-115 ylbP - - K - - - n-acetyltransferase
HGDKEKEP_02645 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HGDKEKEP_02646 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HGDKEKEP_02647 1.15e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HGDKEKEP_02649 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
HGDKEKEP_02650 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HGDKEKEP_02651 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HGDKEKEP_02652 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HGDKEKEP_02653 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGDKEKEP_02654 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HGDKEKEP_02655 4.36e-52 ylbG - - S - - - UPF0298 protein
HGDKEKEP_02656 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HGDKEKEP_02657 1.73e-48 ylbE - - S - - - YlbE-like protein
HGDKEKEP_02658 3.78e-88 ylbD - - S - - - Putative coat protein
HGDKEKEP_02659 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
HGDKEKEP_02660 1.53e-97 ylbB - - T - - - COG0517 FOG CBS domain
HGDKEKEP_02661 1.61e-81 ylbA - - S - - - YugN-like family
HGDKEKEP_02662 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HGDKEKEP_02663 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HGDKEKEP_02664 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HGDKEKEP_02665 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGDKEKEP_02666 9.7e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HGDKEKEP_02667 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HGDKEKEP_02668 4.72e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HGDKEKEP_02669 2.19e-174 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HGDKEKEP_02670 1.9e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HGDKEKEP_02671 2.6e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGDKEKEP_02672 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGDKEKEP_02674 3.69e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGDKEKEP_02675 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HGDKEKEP_02676 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_02677 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HGDKEKEP_02678 6.19e-39 ywdA - - - - - - -
HGDKEKEP_02679 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HGDKEKEP_02680 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
HGDKEKEP_02681 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGDKEKEP_02682 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGDKEKEP_02683 1.26e-62 ywdI - - S - - - Family of unknown function (DUF5327)
HGDKEKEP_02684 1.86e-303 ywdJ - - F - - - Xanthine uracil
HGDKEKEP_02685 1.59e-78 ywdK - - S - - - small membrane protein
HGDKEKEP_02686 3.7e-106 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HGDKEKEP_02687 8.08e-187 spsA - - M - - - Spore Coat
HGDKEKEP_02688 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HGDKEKEP_02689 3.06e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HGDKEKEP_02690 2.01e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HGDKEKEP_02691 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HGDKEKEP_02692 2.47e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
HGDKEKEP_02693 4.71e-239 spsG - - M - - - Spore Coat
HGDKEKEP_02694 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGDKEKEP_02695 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGDKEKEP_02696 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGDKEKEP_02697 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HGDKEKEP_02698 3.7e-101 - - - - - - - -
HGDKEKEP_02699 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGDKEKEP_02700 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HGDKEKEP_02701 0.0 rocB - - E - - - arginine degradation protein
HGDKEKEP_02702 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HGDKEKEP_02703 3.81e-275 ywfA - - EGP - - - -transporter
HGDKEKEP_02704 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HGDKEKEP_02705 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HGDKEKEP_02706 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_02707 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HGDKEKEP_02708 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HGDKEKEP_02709 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HGDKEKEP_02710 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HGDKEKEP_02711 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HGDKEKEP_02712 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HGDKEKEP_02713 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_02714 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HGDKEKEP_02715 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HGDKEKEP_02716 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HGDKEKEP_02717 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HGDKEKEP_02718 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HGDKEKEP_02719 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HGDKEKEP_02720 1.1e-103 yffB - - K - - - Transcriptional regulator
HGDKEKEP_02721 1.54e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HGDKEKEP_02723 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGDKEKEP_02724 1.45e-93 ywhA - - K - - - Transcriptional regulator
HGDKEKEP_02725 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HGDKEKEP_02726 3.29e-154 ywhC - - S - - - Peptidase family M50
HGDKEKEP_02727 1.92e-123 ywhD - - S - - - YwhD family
HGDKEKEP_02728 2.1e-64 - - - - - - - -
HGDKEKEP_02729 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGDKEKEP_02730 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HGDKEKEP_02731 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HGDKEKEP_02732 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
HGDKEKEP_02734 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGDKEKEP_02735 1.4e-155 ywhK - - CO - - - amine dehydrogenase activity
HGDKEKEP_02736 1.57e-96 ywhK - - CO - - - amine dehydrogenase activity
HGDKEKEP_02737 1.31e-303 ywhL - - CO - - - amine dehydrogenase activity
HGDKEKEP_02739 1.17e-315 - - - L - - - Peptidase, M16
HGDKEKEP_02740 3.84e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HGDKEKEP_02741 1.81e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HGDKEKEP_02742 5.02e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HGDKEKEP_02744 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HGDKEKEP_02745 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HGDKEKEP_02746 5.42e-95 ywiB - - S - - - protein conserved in bacteria
HGDKEKEP_02747 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HGDKEKEP_02748 1.47e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HGDKEKEP_02749 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HGDKEKEP_02750 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HGDKEKEP_02751 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HGDKEKEP_02752 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGDKEKEP_02753 5.39e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGDKEKEP_02754 1.28e-201 ywbI - - K - - - Transcriptional regulator
HGDKEKEP_02755 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HGDKEKEP_02756 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HGDKEKEP_02757 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HGDKEKEP_02758 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HGDKEKEP_02759 1.28e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HGDKEKEP_02760 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HGDKEKEP_02761 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
HGDKEKEP_02762 1.81e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGDKEKEP_02763 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGDKEKEP_02764 4.43e-307 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_02765 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HGDKEKEP_02766 5.37e-216 gspA - - M - - - General stress
HGDKEKEP_02767 3.49e-158 ywaF - - S - - - Integral membrane protein
HGDKEKEP_02768 1.25e-114 ywaE - - K - - - Transcriptional regulator
HGDKEKEP_02769 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGDKEKEP_02770 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HGDKEKEP_02771 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HGDKEKEP_02772 5.6e-173 - - - L - - - Integrase core domain
HGDKEKEP_02773 7.55e-59 orfX1 - - L - - - Transposase
HGDKEKEP_02774 1.6e-276 - - - S - - - Phage Terminase
HGDKEKEP_02775 2.58e-14 - - - - - - - -
HGDKEKEP_02776 4.77e-273 - - - S - - - Phage portal protein
HGDKEKEP_02777 9.36e-135 - - - S - - - peptidase activity
HGDKEKEP_02778 3.43e-227 - - - S - - - capsid protein
HGDKEKEP_02779 8.02e-09 - - - S - - - peptidoglycan catabolic process
HGDKEKEP_02780 1.23e-39 - - - S - - - peptidoglycan catabolic process
HGDKEKEP_02781 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
HGDKEKEP_02782 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGDKEKEP_02783 1.42e-40 - - - - - - - -
HGDKEKEP_02784 9.75e-79 - - - - - - - -
HGDKEKEP_02785 1.58e-36 - - - - - - - -
HGDKEKEP_02786 4.09e-16 - - - - - - - -
HGDKEKEP_02787 0.0 - - - S - - - peptidoglycan catabolic process
HGDKEKEP_02788 1.96e-141 - - - S - - - Phage tail protein
HGDKEKEP_02789 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HGDKEKEP_02790 1.92e-275 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HGDKEKEP_02791 1.19e-135 - - - S - - - Phage tail protein
HGDKEKEP_02792 0.0 - - - D - - - phage tail tape measure protein
HGDKEKEP_02794 1.77e-05 - - - - - - - -
HGDKEKEP_02795 1.67e-101 - - - N - - - Phage major tail protein phi13
HGDKEKEP_02797 8.4e-67 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGDKEKEP_02798 5.23e-52 - - - S - - - Phage head-tail joining protein
HGDKEKEP_02799 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
HGDKEKEP_02800 1.89e-34 - - - - - - - -
HGDKEKEP_02801 1.06e-266 - - - S - - - capsid protein
HGDKEKEP_02802 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
HGDKEKEP_02803 2.64e-303 - - - S - - - Phage portal protein
HGDKEKEP_02805 0.0 - - - S - - - Terminase
HGDKEKEP_02806 5.19e-102 - - - L - - - phage terminase small subunit
HGDKEKEP_02807 1.19e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HGDKEKEP_02809 7.11e-39 - - - - - - - -
HGDKEKEP_02810 1.84e-105 - - - L - - - Transposase
HGDKEKEP_02812 6e-147 - - - - - - - -
HGDKEKEP_02813 1.19e-37 - - - - - - - -
HGDKEKEP_02816 1.78e-34 yqaO - - S - - - Phage-like element PBSX protein XtrA
HGDKEKEP_02817 2.02e-81 rusA - - L - - - Endodeoxyribonuclease RusA
HGDKEKEP_02819 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
HGDKEKEP_02820 4.69e-96 yqaL - - L - - - DnaD domain protein
HGDKEKEP_02822 1.8e-87 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HGDKEKEP_02823 8.41e-125 - - - - - - - -
HGDKEKEP_02828 3.14e-110 - - - - - - - -
HGDKEKEP_02829 1.22e-48 - - - S - - - DNA binding
HGDKEKEP_02830 1.68e-48 - - - - - - - -
HGDKEKEP_02831 1.5e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
HGDKEKEP_02832 6.71e-28 - - - K - - - transcriptional
HGDKEKEP_02833 2.71e-61 xkdA - - E - - - IrrE N-terminal-like domain
HGDKEKEP_02834 1.91e-182 - - - L - - - Belongs to the 'phage' integrase family
HGDKEKEP_02835 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGDKEKEP_02836 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGDKEKEP_02837 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HGDKEKEP_02838 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HGDKEKEP_02839 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGDKEKEP_02840 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HGDKEKEP_02841 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGDKEKEP_02842 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGDKEKEP_02843 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HGDKEKEP_02845 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGDKEKEP_02846 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HGDKEKEP_02847 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HGDKEKEP_02848 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HGDKEKEP_02849 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGDKEKEP_02852 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_02853 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HGDKEKEP_02854 3.66e-157 yetF - - S - - - membrane
HGDKEKEP_02855 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HGDKEKEP_02856 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGDKEKEP_02857 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HGDKEKEP_02858 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGDKEKEP_02859 0.0 yetA - - - - - - -
HGDKEKEP_02860 2.25e-127 yetA - - - - - - -
HGDKEKEP_02861 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HGDKEKEP_02862 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGDKEKEP_02863 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HGDKEKEP_02864 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HGDKEKEP_02865 4.69e-144 - - - S - - - Protein of unknown function, DUF624
HGDKEKEP_02866 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
HGDKEKEP_02867 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
HGDKEKEP_02868 0.0 yesS - - K - - - Transcriptional regulator
HGDKEKEP_02869 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HGDKEKEP_02870 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGDKEKEP_02871 3.57e-120 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGDKEKEP_02872 6.98e-77 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HGDKEKEP_02873 5.28e-123 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGDKEKEP_02874 3.95e-184 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HGDKEKEP_02875 1.32e-69 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HGDKEKEP_02876 7.1e-163 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HGDKEKEP_02877 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_02878 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
HGDKEKEP_02879 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HGDKEKEP_02880 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HGDKEKEP_02881 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HGDKEKEP_02882 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HGDKEKEP_02883 1.13e-193 yesF - - GM - - - NAD(P)H-binding
HGDKEKEP_02884 4.59e-101 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
HGDKEKEP_02885 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_02887 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HGDKEKEP_02889 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HGDKEKEP_02890 1.23e-14 - - - S - - - Pfam:DUF1311
HGDKEKEP_02891 2.44e-127 - - - L - - - endonuclease activity
HGDKEKEP_02893 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HGDKEKEP_02894 3.39e-98 - - - S - - - Protein of unknown function, DUF600
HGDKEKEP_02895 5.1e-36 - - - - - - - -
HGDKEKEP_02897 1.59e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_02901 0.0 - - - L - - - Type III restriction enzyme res subunit
HGDKEKEP_02902 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGDKEKEP_02903 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGDKEKEP_02904 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HGDKEKEP_02905 2.08e-190 yerO - - K - - - Transcriptional regulator
HGDKEKEP_02906 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGDKEKEP_02907 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGDKEKEP_02908 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGDKEKEP_02909 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGDKEKEP_02910 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HGDKEKEP_02911 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HGDKEKEP_02912 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HGDKEKEP_02913 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGDKEKEP_02914 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HGDKEKEP_02915 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HGDKEKEP_02917 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HGDKEKEP_02918 6.27e-67 yerC - - S - - - protein conserved in bacteria
HGDKEKEP_02919 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HGDKEKEP_02920 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HGDKEKEP_02921 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HGDKEKEP_02922 1.49e-240 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HGDKEKEP_02923 7.5e-92 - - - K - - - helix_turn_helix ASNC type
HGDKEKEP_02924 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGDKEKEP_02925 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HGDKEKEP_02926 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HGDKEKEP_02927 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HGDKEKEP_02928 1.82e-275 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HGDKEKEP_02929 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HGDKEKEP_02930 5.77e-267 acdA - - I - - - acyl-CoA dehydrogenase
HGDKEKEP_02931 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGDKEKEP_02932 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGDKEKEP_02933 3.26e-72 - - - L - - - transposase activity
HGDKEKEP_02934 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HGDKEKEP_02935 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HGDKEKEP_02936 8.95e-60 yfhJ - - S - - - WVELL protein
HGDKEKEP_02937 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
HGDKEKEP_02938 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
HGDKEKEP_02939 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HGDKEKEP_02940 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HGDKEKEP_02941 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HGDKEKEP_02942 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HGDKEKEP_02943 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HGDKEKEP_02944 1.73e-48 yfhS - - - - - - -
HGDKEKEP_02945 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_02946 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HGDKEKEP_02947 2.01e-49 ygaB - - S - - - YgaB-like protein
HGDKEKEP_02948 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HGDKEKEP_02949 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HGDKEKEP_02950 8.86e-237 ygaE - - S - - - Membrane
HGDKEKEP_02951 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HGDKEKEP_02952 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HGDKEKEP_02953 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HGDKEKEP_02954 5.46e-74 ygzB - - S - - - UPF0295 protein
HGDKEKEP_02955 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HGDKEKEP_02956 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGDKEKEP_02958 1.15e-58 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGDKEKEP_02959 3.66e-78 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HGDKEKEP_02960 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HGDKEKEP_02961 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HGDKEKEP_02962 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HGDKEKEP_02963 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HGDKEKEP_02964 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
HGDKEKEP_02965 7.44e-159 yodN - - - - - - -
HGDKEKEP_02967 5.18e-34 yozD - - S - - - YozD-like protein
HGDKEKEP_02968 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HGDKEKEP_02969 1.17e-71 yodL - - S - - - YodL-like
HGDKEKEP_02970 2.08e-12 - - - - - - - -
HGDKEKEP_02971 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HGDKEKEP_02972 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HGDKEKEP_02973 2.81e-40 yodI - - - - - - -
HGDKEKEP_02974 3.03e-166 yodH - - Q - - - Methyltransferase
HGDKEKEP_02975 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HGDKEKEP_02976 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGDKEKEP_02977 3.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HGDKEKEP_02978 5.61e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGDKEKEP_02979 2.17e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HGDKEKEP_02980 1.92e-140 yodC - - C - - - nitroreductase
HGDKEKEP_02981 2.63e-73 yodB - - K - - - transcriptional
HGDKEKEP_02982 5.64e-84 iolK - - S - - - tautomerase
HGDKEKEP_02983 3.6e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HGDKEKEP_02984 1.13e-13 - - - - - - - -
HGDKEKEP_02985 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HGDKEKEP_02986 6.68e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HGDKEKEP_02987 1.85e-58 - - - - - - - -
HGDKEKEP_02988 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HGDKEKEP_02989 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HGDKEKEP_02990 2.91e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGDKEKEP_02991 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HGDKEKEP_02993 2.14e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGDKEKEP_02994 3.12e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HGDKEKEP_02995 2.48e-262 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HGDKEKEP_02996 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGDKEKEP_02997 7.38e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HGDKEKEP_02998 0.0 yojO - - P - - - Von Willebrand factor
HGDKEKEP_02999 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HGDKEKEP_03000 1.05e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HGDKEKEP_03001 2.1e-39 - - - - - - - -
HGDKEKEP_03002 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HGDKEKEP_03003 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HGDKEKEP_03004 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HGDKEKEP_03005 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGDKEKEP_03006 5.14e-161 yfmS - - NT - - - chemotaxis protein
HGDKEKEP_03007 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGDKEKEP_03008 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HGDKEKEP_03009 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HGDKEKEP_03010 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_03011 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HGDKEKEP_03012 6.7e-284 yfnE - - S - - - Glycosyltransferase like family 2
HGDKEKEP_03013 2.69e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HGDKEKEP_03014 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HGDKEKEP_03015 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HGDKEKEP_03016 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGDKEKEP_03017 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HGDKEKEP_03018 1.94e-248 yetN - - S - - - Protein of unknown function (DUF3900)
HGDKEKEP_03019 5.94e-131 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HGDKEKEP_03020 1.3e-38 yetM - - CH - - - FAD binding domain
HGDKEKEP_03021 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HGDKEKEP_03022 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HGDKEKEP_03023 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGDKEKEP_03024 5.47e-234 yplP - - K - - - Transcriptional regulator
HGDKEKEP_03025 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HGDKEKEP_03026 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HGDKEKEP_03027 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGDKEKEP_03028 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HGDKEKEP_03029 2.01e-147 ypjP - - S - - - YpjP-like protein
HGDKEKEP_03030 5.05e-186 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HGDKEKEP_03031 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HGDKEKEP_03032 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HGDKEKEP_03033 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HGDKEKEP_03034 7.22e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HGDKEKEP_03035 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HGDKEKEP_03036 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGDKEKEP_03037 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HGDKEKEP_03038 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HGDKEKEP_03039 1.17e-22 degR - - - - - - -
HGDKEKEP_03040 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HGDKEKEP_03041 1.54e-37 ypeQ - - S - - - Zinc-finger
HGDKEKEP_03042 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HGDKEKEP_03043 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HGDKEKEP_03044 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HGDKEKEP_03045 2.59e-05 - - - - ko:K06429 - ko00000 -
HGDKEKEP_03046 1.12e-94 ypcP - - L - - - 5'3' exonuclease
HGDKEKEP_03047 1e-81 ypcP - - L - - - 5'3' exonuclease
HGDKEKEP_03048 1.08e-11 - - - - - - - -
HGDKEKEP_03049 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HGDKEKEP_03050 0.0 ypbR - - S - - - Dynamin family
HGDKEKEP_03051 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HGDKEKEP_03052 4.08e-41 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HGDKEKEP_03053 1.49e-201 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HGDKEKEP_03054 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HGDKEKEP_03055 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGDKEKEP_03056 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HGDKEKEP_03057 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HGDKEKEP_03058 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HGDKEKEP_03059 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HGDKEKEP_03060 2.24e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HGDKEKEP_03061 7.26e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HGDKEKEP_03062 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_03063 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HGDKEKEP_03065 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HGDKEKEP_03066 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGDKEKEP_03067 1.39e-127 ypsA - - S - - - Belongs to the UPF0398 family
HGDKEKEP_03068 2.81e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HGDKEKEP_03069 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HGDKEKEP_03070 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HGDKEKEP_03071 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGDKEKEP_03072 8.36e-66 yppG - - S - - - YppG-like protein
HGDKEKEP_03073 9.21e-11 - - - S - - - YppF-like protein
HGDKEKEP_03074 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HGDKEKEP_03077 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
HGDKEKEP_03078 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGDKEKEP_03079 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HGDKEKEP_03080 1.43e-121 ypoC - - - - - - -
HGDKEKEP_03081 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGDKEKEP_03082 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HGDKEKEP_03083 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HGDKEKEP_03084 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HGDKEKEP_03085 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HGDKEKEP_03086 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HGDKEKEP_03087 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HGDKEKEP_03088 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HGDKEKEP_03089 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGDKEKEP_03090 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HGDKEKEP_03091 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGDKEKEP_03092 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGDKEKEP_03093 7.01e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HGDKEKEP_03094 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HGDKEKEP_03095 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HGDKEKEP_03096 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGDKEKEP_03097 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HGDKEKEP_03098 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGDKEKEP_03099 6.56e-181 ypjB - - S - - - sporulation protein
HGDKEKEP_03100 1.15e-125 ypjA - - S - - - membrane
HGDKEKEP_03101 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HGDKEKEP_03102 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HGDKEKEP_03103 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HGDKEKEP_03104 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HGDKEKEP_03105 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
HGDKEKEP_03106 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
HGDKEKEP_03107 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGDKEKEP_03108 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HGDKEKEP_03109 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGDKEKEP_03110 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HGDKEKEP_03111 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HGDKEKEP_03112 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HGDKEKEP_03113 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HGDKEKEP_03114 2.37e-227 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGDKEKEP_03115 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGDKEKEP_03116 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HGDKEKEP_03117 3.86e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGDKEKEP_03118 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGDKEKEP_03119 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HGDKEKEP_03120 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HGDKEKEP_03121 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HGDKEKEP_03122 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGDKEKEP_03123 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HGDKEKEP_03124 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HGDKEKEP_03125 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HGDKEKEP_03127 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HGDKEKEP_03128 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HGDKEKEP_03129 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HGDKEKEP_03130 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HGDKEKEP_03131 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HGDKEKEP_03132 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HGDKEKEP_03133 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGDKEKEP_03134 1.15e-43 ynzC - - S - - - UPF0291 protein
HGDKEKEP_03135 5.4e-143 yneB - - L - - - resolvase
HGDKEKEP_03136 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HGDKEKEP_03137 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGDKEKEP_03138 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HGDKEKEP_03139 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
HGDKEKEP_03140 6.31e-173 yndL - - S - - - Replication protein
HGDKEKEP_03143 0.0 yndJ - - S - - - YndJ-like protein
HGDKEKEP_03144 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
HGDKEKEP_03145 2.52e-196 yndG - - S - - - DoxX-like family
HGDKEKEP_03146 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HGDKEKEP_03147 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGDKEKEP_03148 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HGDKEKEP_03151 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HGDKEKEP_03152 8.92e-96 - - - - - - - -
HGDKEKEP_03153 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HGDKEKEP_03156 2.43e-162 - - - S - - - Domain of unknown function, YrpD
HGDKEKEP_03158 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGDKEKEP_03161 7.54e-22 - - - - - - - -
HGDKEKEP_03162 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HGDKEKEP_03164 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGDKEKEP_03165 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_03166 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HGDKEKEP_03167 9.01e-218 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HGDKEKEP_03168 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HGDKEKEP_03169 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HGDKEKEP_03170 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGDKEKEP_03171 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGDKEKEP_03172 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGDKEKEP_03173 1.06e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGDKEKEP_03174 4.35e-32 yqzJ - - - - - - -
HGDKEKEP_03175 1.47e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGDKEKEP_03176 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HGDKEKEP_03177 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HGDKEKEP_03178 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HGDKEKEP_03179 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HGDKEKEP_03181 9.84e-128 yqjB - - S - - - protein conserved in bacteria
HGDKEKEP_03182 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HGDKEKEP_03183 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGDKEKEP_03184 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGDKEKEP_03185 4.79e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HGDKEKEP_03186 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HGDKEKEP_03187 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HGDKEKEP_03188 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_03189 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HGDKEKEP_03190 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGDKEKEP_03191 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGDKEKEP_03192 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGDKEKEP_03193 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGDKEKEP_03194 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HGDKEKEP_03195 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HGDKEKEP_03196 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HGDKEKEP_03197 0.0 bkdR - - KT - - - Transcriptional regulator
HGDKEKEP_03198 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HGDKEKEP_03199 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HGDKEKEP_03200 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HGDKEKEP_03201 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGDKEKEP_03202 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HGDKEKEP_03203 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HGDKEKEP_03204 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HGDKEKEP_03205 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HGDKEKEP_03206 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HGDKEKEP_03207 4.74e-37 - - - - - - - -
HGDKEKEP_03208 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HGDKEKEP_03210 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HGDKEKEP_03211 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HGDKEKEP_03212 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HGDKEKEP_03213 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HGDKEKEP_03214 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HGDKEKEP_03215 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGDKEKEP_03216 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HGDKEKEP_03217 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGDKEKEP_03218 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGDKEKEP_03219 1.45e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGDKEKEP_03220 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGDKEKEP_03221 9.55e-88 yqhY - - S - - - protein conserved in bacteria
HGDKEKEP_03222 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HGDKEKEP_03223 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGDKEKEP_03224 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HGDKEKEP_03225 7.6e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HGDKEKEP_03226 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HGDKEKEP_03227 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HGDKEKEP_03228 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HGDKEKEP_03229 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HGDKEKEP_03230 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HGDKEKEP_03231 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HGDKEKEP_03232 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HGDKEKEP_03233 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGDKEKEP_03234 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HGDKEKEP_03235 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HGDKEKEP_03236 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HGDKEKEP_03237 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HGDKEKEP_03238 5.18e-81 yqhP - - - - - - -
HGDKEKEP_03239 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HGDKEKEP_03240 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HGDKEKEP_03241 2.63e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HGDKEKEP_03242 2.51e-81 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HGDKEKEP_03243 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGDKEKEP_03244 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGDKEKEP_03245 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HGDKEKEP_03246 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HGDKEKEP_03247 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
HGDKEKEP_03248 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HGDKEKEP_03249 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HGDKEKEP_03250 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HGDKEKEP_03251 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HGDKEKEP_03252 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
HGDKEKEP_03253 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HGDKEKEP_03254 2.84e-36 yqzE - - S - - - YqzE-like protein
HGDKEKEP_03255 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HGDKEKEP_03256 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HGDKEKEP_03257 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HGDKEKEP_03258 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HGDKEKEP_03259 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HGDKEKEP_03260 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HGDKEKEP_03261 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGDKEKEP_03262 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
HGDKEKEP_03263 8.73e-233 yqxL - - P - - - Mg2 transporter protein
HGDKEKEP_03264 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGDKEKEP_03265 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HGDKEKEP_03267 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HGDKEKEP_03268 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HGDKEKEP_03270 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGDKEKEP_03271 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGDKEKEP_03272 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGDKEKEP_03273 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HGDKEKEP_03274 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HGDKEKEP_03275 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HGDKEKEP_03276 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HGDKEKEP_03277 1.38e-73 swrA - - S - - - Swarming motility protein
HGDKEKEP_03278 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGDKEKEP_03279 3.03e-295 yvkA - - P - - - -transporter
HGDKEKEP_03280 1.43e-131 yvkB - - K - - - Transcriptional regulator
HGDKEKEP_03281 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HGDKEKEP_03282 2.54e-42 csbA - - S - - - protein conserved in bacteria
HGDKEKEP_03283 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGDKEKEP_03284 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGDKEKEP_03285 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HGDKEKEP_03286 2.25e-45 yvkN - - - - - - -
HGDKEKEP_03287 8.09e-65 yvlA - - - - - - -
HGDKEKEP_03288 5.54e-219 yvlB - - S - - - Putative adhesin
HGDKEKEP_03289 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HGDKEKEP_03290 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HGDKEKEP_03291 9.58e-67 - - - M - - - ArpU family transcriptional regulator
HGDKEKEP_03292 1.6e-94 - - - L - - - Phage integrase family
HGDKEKEP_03293 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGDKEKEP_03294 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HGDKEKEP_03295 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HGDKEKEP_03296 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGDKEKEP_03297 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGDKEKEP_03302 5.52e-31 - - - M - - - ArpU family transcriptional regulator
HGDKEKEP_03303 5.89e-58 - - - L - - - Phage integrase family
HGDKEKEP_03311 1.89e-40 - - - - - - - -
HGDKEKEP_03312 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
HGDKEKEP_03316 5.24e-60 - - - - - - - -
HGDKEKEP_03317 1.1e-20 - - - S - - - SMI1 / KNR4 family
HGDKEKEP_03318 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
HGDKEKEP_03320 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HGDKEKEP_03321 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HGDKEKEP_03322 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGDKEKEP_03323 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
HGDKEKEP_03325 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
HGDKEKEP_03326 1.14e-197 yybE - - K - - - Transcriptional regulator
HGDKEKEP_03327 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGDKEKEP_03328 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_03329 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HGDKEKEP_03330 7.4e-168 - - - - - - - -
HGDKEKEP_03331 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HGDKEKEP_03332 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
HGDKEKEP_03333 2.3e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HGDKEKEP_03334 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HGDKEKEP_03336 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HGDKEKEP_03337 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HGDKEKEP_03338 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGDKEKEP_03339 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HGDKEKEP_03340 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGDKEKEP_03341 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HGDKEKEP_03342 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGDKEKEP_03343 7.73e-176 yqeM - - Q - - - Methyltransferase
HGDKEKEP_03344 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGDKEKEP_03345 3.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HGDKEKEP_03346 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HGDKEKEP_03347 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HGDKEKEP_03348 2.36e-22 - - - S - - - YqzM-like protein
HGDKEKEP_03349 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HGDKEKEP_03350 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HGDKEKEP_03351 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HGDKEKEP_03352 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HGDKEKEP_03353 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
HGDKEKEP_03354 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGDKEKEP_03355 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HGDKEKEP_03356 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGDKEKEP_03357 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGDKEKEP_03358 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HGDKEKEP_03359 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGDKEKEP_03360 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HGDKEKEP_03361 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGDKEKEP_03362 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HGDKEKEP_03363 4.64e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HGDKEKEP_03364 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HGDKEKEP_03365 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HGDKEKEP_03366 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HGDKEKEP_03367 4.35e-192 yqfA - - S - - - UPF0365 protein
HGDKEKEP_03368 2.23e-56 yqfB - - - - - - -
HGDKEKEP_03369 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HGDKEKEP_03370 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HGDKEKEP_03371 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HGDKEKEP_03373 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HGDKEKEP_03374 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGDKEKEP_03375 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HGDKEKEP_03376 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HGDKEKEP_03377 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGDKEKEP_03378 5.29e-27 - - - S - - - YqzL-like protein
HGDKEKEP_03379 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HGDKEKEP_03380 6.07e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HGDKEKEP_03381 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HGDKEKEP_03382 3.29e-144 ccpN - - K - - - CBS domain
HGDKEKEP_03383 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HGDKEKEP_03384 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HGDKEKEP_03385 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGDKEKEP_03386 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGDKEKEP_03387 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HGDKEKEP_03388 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HGDKEKEP_03389 7.29e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGDKEKEP_03390 1.01e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGDKEKEP_03391 1.05e-48 yqfQ - - S - - - YqfQ-like protein
HGDKEKEP_03392 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGDKEKEP_03393 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HGDKEKEP_03394 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HGDKEKEP_03395 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGDKEKEP_03396 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HGDKEKEP_03397 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HGDKEKEP_03398 2.38e-80 yqfX - - S - - - membrane
HGDKEKEP_03399 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGDKEKEP_03400 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
HGDKEKEP_03401 1.12e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
HGDKEKEP_03402 2.36e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HGDKEKEP_03403 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HGDKEKEP_03404 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HGDKEKEP_03405 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HGDKEKEP_03406 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HGDKEKEP_03407 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HGDKEKEP_03408 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HGDKEKEP_03409 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGDKEKEP_03410 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGDKEKEP_03411 1.09e-93 yqzC - - S - - - YceG-like family
HGDKEKEP_03412 2.81e-67 yqzD - - - - - - -
HGDKEKEP_03414 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HGDKEKEP_03415 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HGDKEKEP_03416 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGDKEKEP_03417 3.38e-14 yqgO - - - - - - -
HGDKEKEP_03418 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HGDKEKEP_03419 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HGDKEKEP_03420 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HGDKEKEP_03421 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGDKEKEP_03422 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HGDKEKEP_03423 2.69e-256 yqgU - - - - - - -
HGDKEKEP_03424 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HGDKEKEP_03425 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HGDKEKEP_03426 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HGDKEKEP_03427 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HGDKEKEP_03428 8.69e-184 - - - - - - - -
HGDKEKEP_03429 7.04e-118 yocC - - - - - - -
HGDKEKEP_03430 1.41e-242 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HGDKEKEP_03431 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HGDKEKEP_03432 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_03433 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_03435 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
HGDKEKEP_03436 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HGDKEKEP_03437 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGDKEKEP_03438 2.87e-107 yocK - - T - - - general stress protein
HGDKEKEP_03439 4.29e-70 yocL - - - - - - -
HGDKEKEP_03440 3.93e-41 - - - - - - - -
HGDKEKEP_03441 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HGDKEKEP_03442 2.94e-55 yozN - - - - - - -
HGDKEKEP_03443 1.83e-49 yocN - - - - - - -
HGDKEKEP_03444 2.17e-74 yozO - - S - - - Bacterial PH domain
HGDKEKEP_03445 1.91e-42 yozC - - - - - - -
HGDKEKEP_03446 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HGDKEKEP_03447 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HGDKEKEP_03448 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HGDKEKEP_03449 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HGDKEKEP_03450 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
HGDKEKEP_03452 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HGDKEKEP_03453 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGDKEKEP_03454 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HGDKEKEP_03455 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_03457 2.14e-17 - - - Q - - - methyltransferase
HGDKEKEP_03458 1.08e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HGDKEKEP_03459 0.000751 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HGDKEKEP_03460 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HGDKEKEP_03462 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_03464 4.46e-23 - - - - - - - -
HGDKEKEP_03465 3.2e-59 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HGDKEKEP_03466 7.66e-99 - - - - - - - -
HGDKEKEP_03467 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGDKEKEP_03468 4.98e-106 yoaW - - - - - - -
HGDKEKEP_03469 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGDKEKEP_03471 2.82e-104 - - - S - - - Domain of unknown function (DUF3885)
HGDKEKEP_03472 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HGDKEKEP_03473 1.79e-84 ydjM - - M - - - Lytic transglycolase
HGDKEKEP_03474 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HGDKEKEP_03475 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGDKEKEP_03476 1.91e-33 - - - S - - - Ion transport 2 domain protein
HGDKEKEP_03477 4.11e-183 - - - S - - - Ion transport 2 domain protein
HGDKEKEP_03478 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HGDKEKEP_03479 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HGDKEKEP_03480 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGDKEKEP_03481 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HGDKEKEP_03482 4.95e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HGDKEKEP_03483 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HGDKEKEP_03484 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HGDKEKEP_03485 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HGDKEKEP_03486 5.53e-175 - - - - - - - -
HGDKEKEP_03487 1.17e-148 - - - - - - - -
HGDKEKEP_03491 5.85e-35 - - - U - - - Preprotein translocase subunit SecB
HGDKEKEP_03493 6.75e-38 - - - K - - - Helix-turn-helix domain
HGDKEKEP_03495 7.52e-55 - - - S - - - protein domain associated with
HGDKEKEP_03497 6.57e-233 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGDKEKEP_03498 8.88e-87 - - - S - - - Immunity protein 70
HGDKEKEP_03499 7.81e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGDKEKEP_03500 3.19e-41 xhlB - - S - - - SPP1 phage holin
HGDKEKEP_03501 1.81e-37 bhlA - - S - - - BhlA holin family
HGDKEKEP_03504 4.54e-205 ytbE - - S - - - reductase
HGDKEKEP_03505 1.6e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HGDKEKEP_03506 1.15e-86 ytcD - - K - - - Transcriptional regulator
HGDKEKEP_03507 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGDKEKEP_03508 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HGDKEKEP_03509 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGDKEKEP_03510 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HGDKEKEP_03511 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HGDKEKEP_03512 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HGDKEKEP_03513 2e-204 ytxC - - S - - - YtxC-like family
HGDKEKEP_03515 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGDKEKEP_03516 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HGDKEKEP_03517 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_03518 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HGDKEKEP_03519 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGDKEKEP_03520 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HGDKEKEP_03522 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGDKEKEP_03523 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HGDKEKEP_03524 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGDKEKEP_03525 3.65e-59 ysdA - - S - - - Membrane
HGDKEKEP_03526 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HGDKEKEP_03527 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
HGDKEKEP_03528 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HGDKEKEP_03529 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HGDKEKEP_03530 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HGDKEKEP_03531 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HGDKEKEP_03532 1.46e-87 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HGDKEKEP_03533 2.52e-61 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HGDKEKEP_03534 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HGDKEKEP_03535 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HGDKEKEP_03536 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HGDKEKEP_03537 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HGDKEKEP_03538 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HGDKEKEP_03539 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HGDKEKEP_03540 8.42e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HGDKEKEP_03541 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HGDKEKEP_03542 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HGDKEKEP_03543 3.19e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HGDKEKEP_03544 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HGDKEKEP_03545 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGDKEKEP_03546 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGDKEKEP_03547 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGDKEKEP_03548 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGDKEKEP_03549 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HGDKEKEP_03550 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
HGDKEKEP_03551 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HGDKEKEP_03552 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGDKEKEP_03553 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HGDKEKEP_03554 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HGDKEKEP_03555 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_03556 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HGDKEKEP_03557 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HGDKEKEP_03558 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HGDKEKEP_03560 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HGDKEKEP_03561 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HGDKEKEP_03562 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGDKEKEP_03563 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGDKEKEP_03564 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HGDKEKEP_03565 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HGDKEKEP_03566 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HGDKEKEP_03567 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HGDKEKEP_03568 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HGDKEKEP_03569 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HGDKEKEP_03570 1.15e-191 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HGDKEKEP_03571 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03572 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03573 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HGDKEKEP_03574 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HGDKEKEP_03575 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HGDKEKEP_03576 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HGDKEKEP_03577 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HGDKEKEP_03578 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGDKEKEP_03579 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HGDKEKEP_03580 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HGDKEKEP_03581 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HGDKEKEP_03582 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGDKEKEP_03583 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HGDKEKEP_03584 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HGDKEKEP_03585 3.28e-155 yflK - - S - - - protein conserved in bacteria
HGDKEKEP_03586 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HGDKEKEP_03587 6.9e-27 yflI - - - - - - -
HGDKEKEP_03588 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
HGDKEKEP_03589 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HGDKEKEP_03590 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HGDKEKEP_03591 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HGDKEKEP_03592 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HGDKEKEP_03593 1.43e-41 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HGDKEKEP_03594 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_03595 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HGDKEKEP_03596 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HGDKEKEP_03597 6.16e-160 frp - - C - - - nitroreductase
HGDKEKEP_03598 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HGDKEKEP_03599 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HGDKEKEP_03600 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_03601 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
HGDKEKEP_03602 5.89e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGDKEKEP_03603 1.03e-66 yfkI - - S - - - gas vesicle protein
HGDKEKEP_03604 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HGDKEKEP_03605 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_03606 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HGDKEKEP_03607 3.69e-189 yfkD - - S - - - YfkD-like protein
HGDKEKEP_03608 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HGDKEKEP_03609 1.76e-283 yfkA - - S - - - YfkB-like domain
HGDKEKEP_03610 3.26e-36 yfjT - - - - - - -
HGDKEKEP_03611 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HGDKEKEP_03612 2.29e-192 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HGDKEKEP_03613 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HGDKEKEP_03614 3.92e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HGDKEKEP_03615 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGDKEKEP_03616 3.04e-59 - - - S - - - YfzA-like protein
HGDKEKEP_03617 1.25e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGDKEKEP_03618 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
HGDKEKEP_03620 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HGDKEKEP_03621 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HGDKEKEP_03622 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGDKEKEP_03623 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HGDKEKEP_03624 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HGDKEKEP_03625 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HGDKEKEP_03626 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HGDKEKEP_03627 1e-105 - - - S - - - Family of unknown function (DUF5381)
HGDKEKEP_03628 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HGDKEKEP_03629 1.02e-184 yfjC - - - - - - -
HGDKEKEP_03630 1.94e-270 yfjB - - - - - - -
HGDKEKEP_03631 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HGDKEKEP_03632 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGDKEKEP_03633 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HGDKEKEP_03634 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_03635 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HGDKEKEP_03636 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGDKEKEP_03637 1.93e-82 yfiD3 - - S - - - DoxX
HGDKEKEP_03638 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HGDKEKEP_03640 1.7e-272 baeS - - T - - - Histidine kinase
HGDKEKEP_03641 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HGDKEKEP_03642 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_03643 5.69e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HGDKEKEP_03644 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HGDKEKEP_03645 1.89e-128 padR - - K - - - transcriptional
HGDKEKEP_03646 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGDKEKEP_03647 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HGDKEKEP_03648 4.01e-139 yfiR - - K - - - Transcriptional regulator
HGDKEKEP_03649 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
HGDKEKEP_03650 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HGDKEKEP_03651 1.11e-291 yfiU - - EGP - - - the major facilitator superfamily
HGDKEKEP_03652 7.8e-22 yfiU - - EGP - - - the major facilitator superfamily
HGDKEKEP_03653 4.26e-103 yfiV - - K - - - transcriptional
HGDKEKEP_03654 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGDKEKEP_03655 1.28e-229 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HGDKEKEP_03656 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03657 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03658 9.95e-211 yfhB - - S - - - PhzF family
HGDKEKEP_03659 1.17e-137 yfhC - - C - - - nitroreductase
HGDKEKEP_03660 8.86e-35 yfhD - - S - - - YfhD-like protein
HGDKEKEP_03662 2.56e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HGDKEKEP_03663 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HGDKEKEP_03664 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HGDKEKEP_03666 2.45e-268 yfhI - - EGP - - - -transporter
HGDKEKEP_03668 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HGDKEKEP_03669 1.3e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HGDKEKEP_03670 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HGDKEKEP_03671 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGDKEKEP_03672 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HGDKEKEP_03673 5.11e-49 ydaS - - S - - - membrane
HGDKEKEP_03674 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HGDKEKEP_03675 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGDKEKEP_03676 3.33e-77 gtcA - - S - - - GtrA-like protein
HGDKEKEP_03677 1.98e-157 ywcC - - K - - - transcriptional regulator
HGDKEKEP_03679 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
HGDKEKEP_03680 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGDKEKEP_03681 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_03682 4.65e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
HGDKEKEP_03683 1.49e-192 ybdN - - - - - - -
HGDKEKEP_03684 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HGDKEKEP_03686 2.05e-131 - - - T - - - His Kinase A (phospho-acceptor) domain
HGDKEKEP_03687 1.89e-70 - - - T - - - His Kinase A (phospho-acceptor) domain
HGDKEKEP_03688 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HGDKEKEP_03689 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HGDKEKEP_03690 5.59e-64 - - - - - - - -
HGDKEKEP_03691 1.34e-120 ybcF - - P - - - carbonic anhydrase
HGDKEKEP_03692 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HGDKEKEP_03693 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGDKEKEP_03694 8.33e-58 - - - S - - - Metallo-beta-lactamase superfamily
HGDKEKEP_03695 1.42e-56 - - - S - - - MepB protein
HGDKEKEP_03696 0.0 - - - IQ ko:K15641,ko:K16398,ko:K16417,ko:K20788 ko01052,map01052 ko00000,ko00001,ko01008 PKS_KR
HGDKEKEP_03697 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGDKEKEP_03698 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HGDKEKEP_03699 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HGDKEKEP_03700 5.28e-202 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGDKEKEP_03701 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGDKEKEP_03702 1.31e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGDKEKEP_03703 1.81e-41 yazB - - K - - - transcriptional
HGDKEKEP_03704 3.75e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGDKEKEP_03705 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HGDKEKEP_03706 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HGDKEKEP_03707 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HGDKEKEP_03708 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HGDKEKEP_03709 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HGDKEKEP_03710 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGDKEKEP_03711 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HGDKEKEP_03712 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HGDKEKEP_03713 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HGDKEKEP_03714 4.4e-63 ylaH - - S - - - YlaH-like protein
HGDKEKEP_03715 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HGDKEKEP_03716 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HGDKEKEP_03717 1.74e-57 ylaE - - - - - - -
HGDKEKEP_03719 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_03720 1.44e-56 ylaB - - - - - - -
HGDKEKEP_03721 0.0 ylaA - - - - - - -
HGDKEKEP_03722 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HGDKEKEP_03723 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HGDKEKEP_03724 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
HGDKEKEP_03725 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HGDKEKEP_03726 4.48e-35 ykzI - - - - - - -
HGDKEKEP_03727 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
HGDKEKEP_03728 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
HGDKEKEP_03729 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HGDKEKEP_03735 3.93e-73 - - - L - - - Terminase, small subunit
HGDKEKEP_03736 1.19e-179 terL - - S - - - Terminase
HGDKEKEP_03738 1.33e-216 - - - S - - - portal protein
HGDKEKEP_03739 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HGDKEKEP_03740 7.58e-162 - - - S - - - capsid protein
HGDKEKEP_03741 5.45e-13 - - - - - - - -
HGDKEKEP_03743 8.17e-38 - - - S - - - Phage head-tail joining protein
HGDKEKEP_03744 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HGDKEKEP_03746 1.46e-33 - - - - - - - -
HGDKEKEP_03749 0.0 - - - D - - - Phage tail tape measure protein
HGDKEKEP_03751 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HGDKEKEP_03752 0.0 - - - - - - - -
HGDKEKEP_03753 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HGDKEKEP_03754 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HGDKEKEP_03755 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HGDKEKEP_03756 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGDKEKEP_03757 2.92e-88 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGDKEKEP_03758 7.68e-25 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HGDKEKEP_03759 0.0 - - - S - - - Fusaric acid resistance protein-like
HGDKEKEP_03760 1.94e-95 yvaD - - S - - - Family of unknown function (DUF5360)
HGDKEKEP_03761 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HGDKEKEP_03762 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HGDKEKEP_03763 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_03766 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HGDKEKEP_03771 4.26e-220 - - - S - - - Alpha/beta hydrolase family
HGDKEKEP_03772 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HGDKEKEP_03773 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
HGDKEKEP_03774 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGDKEKEP_03775 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HGDKEKEP_03776 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HGDKEKEP_03777 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HGDKEKEP_03778 2.1e-71 ydfQ - - CO - - - Thioredoxin
HGDKEKEP_03779 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HGDKEKEP_03780 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HGDKEKEP_03781 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HGDKEKEP_03782 1.15e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HGDKEKEP_03783 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HGDKEKEP_03784 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_03785 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HGDKEKEP_03786 1.53e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HGDKEKEP_03787 1.03e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HGDKEKEP_03788 8.14e-128 - - - G ko:K03292 - ko00000 symporter YjmB
HGDKEKEP_03789 1.13e-165 - - - G ko:K03292 - ko00000 symporter YjmB
HGDKEKEP_03790 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HGDKEKEP_03791 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HGDKEKEP_03792 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HGDKEKEP_03793 4.85e-54 yjlB - - S - - - Cupin domain
HGDKEKEP_03794 1.26e-20 yjlB - - S - - - Cupin domain
HGDKEKEP_03795 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HGDKEKEP_03796 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HGDKEKEP_03797 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HGDKEKEP_03798 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGDKEKEP_03799 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HGDKEKEP_03800 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_03801 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HGDKEKEP_03802 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HGDKEKEP_03803 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_03805 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
HGDKEKEP_03807 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HGDKEKEP_03808 1.87e-65 yqiX - - S - - - YolD-like protein
HGDKEKEP_03809 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HGDKEKEP_03810 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HGDKEKEP_03811 3.23e-248 yqkA - - K - - - GrpB protein
HGDKEKEP_03812 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HGDKEKEP_03813 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HGDKEKEP_03814 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HGDKEKEP_03815 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
HGDKEKEP_03816 2.09e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HGDKEKEP_03817 6.19e-09 - - - S - - - Protein of unknown function (DUF3936)
HGDKEKEP_03818 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HGDKEKEP_03819 1.45e-280 yqxK - - L - - - DNA helicase
HGDKEKEP_03820 3.18e-77 ansR - - K - - - Transcriptional regulator
HGDKEKEP_03821 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HGDKEKEP_03822 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HGDKEKEP_03823 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HGDKEKEP_03824 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HGDKEKEP_03825 1.47e-41 yqkK - - - - - - -
HGDKEKEP_03826 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HGDKEKEP_03827 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HGDKEKEP_03828 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
HGDKEKEP_03829 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HGDKEKEP_03830 3.77e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGDKEKEP_03831 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGDKEKEP_03832 8.27e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HGDKEKEP_03833 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HGDKEKEP_03834 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HGDKEKEP_03835 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGDKEKEP_03836 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HGDKEKEP_03837 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HGDKEKEP_03838 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HGDKEKEP_03839 8.55e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HGDKEKEP_03840 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HGDKEKEP_03841 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HGDKEKEP_03842 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HGDKEKEP_03843 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGDKEKEP_03844 3.12e-192 ypuA - - S - - - Secreted protein
HGDKEKEP_03845 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGDKEKEP_03846 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGDKEKEP_03849 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HGDKEKEP_03850 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HGDKEKEP_03851 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGDKEKEP_03853 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HGDKEKEP_03854 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HGDKEKEP_03855 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HGDKEKEP_03856 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HGDKEKEP_03857 1.34e-74 - - - - - - - -
HGDKEKEP_03858 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HGDKEKEP_03859 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HGDKEKEP_03860 1.34e-132 ycnI - - S - - - protein conserved in bacteria
HGDKEKEP_03861 3.27e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_03862 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HGDKEKEP_03863 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HGDKEKEP_03864 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGDKEKEP_03865 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_03866 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGDKEKEP_03867 1.68e-60 ycnE - - S - - - Monooxygenase
HGDKEKEP_03868 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HGDKEKEP_03869 5.87e-198 ycnC - - K - - - Transcriptional regulator
HGDKEKEP_03870 0.0 ycnB - - EGP - - - the major facilitator superfamily
HGDKEKEP_03871 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HGDKEKEP_03872 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_03873 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03874 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGDKEKEP_03875 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HGDKEKEP_03876 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HGDKEKEP_03877 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HGDKEKEP_03879 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HGDKEKEP_03880 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HGDKEKEP_03881 2.09e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_03882 5.23e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HGDKEKEP_03883 1.33e-152 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HGDKEKEP_03884 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HGDKEKEP_03885 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
HGDKEKEP_03886 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HGDKEKEP_03889 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
HGDKEKEP_03890 1.46e-201 - - - I - - - Alpha/beta hydrolase family
HGDKEKEP_03891 6.33e-103 yeaA - - S - - - Protein of unknown function (DUF4003)
HGDKEKEP_03892 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HGDKEKEP_03893 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HGDKEKEP_03894 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGDKEKEP_03895 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HGDKEKEP_03896 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HGDKEKEP_03897 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HGDKEKEP_03898 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HGDKEKEP_03899 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_03900 1.15e-314 - - - S - - - Domain of unknown function (DUF4179)
HGDKEKEP_03901 6.6e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HGDKEKEP_03902 5.85e-165 yebC - - M - - - Membrane
HGDKEKEP_03905 0.000711 - - - - - - - -
HGDKEKEP_03906 1.9e-77 - - - S - - - HNH endonuclease
HGDKEKEP_03907 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
HGDKEKEP_03908 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HGDKEKEP_03909 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_03910 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HGDKEKEP_03911 1.05e-22 - - - - - - - -
HGDKEKEP_03912 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HGDKEKEP_03913 3.71e-110 ykyB - - S - - - YkyB-like protein
HGDKEKEP_03914 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_03915 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HGDKEKEP_03916 1.42e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HGDKEKEP_03917 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_03918 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HGDKEKEP_03919 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HGDKEKEP_03920 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HGDKEKEP_03921 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HGDKEKEP_03922 6.01e-99 ykuL - - S - - - CBS domain
HGDKEKEP_03923 7.61e-215 ccpC - - K - - - Transcriptional regulator
HGDKEKEP_03924 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
HGDKEKEP_03925 1.74e-222 ykuO - - - - - - -
HGDKEKEP_03926 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HGDKEKEP_03927 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGDKEKEP_03928 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGDKEKEP_03929 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HGDKEKEP_03930 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HGDKEKEP_03931 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HGDKEKEP_03932 4.23e-104 ykuV - - CO - - - thiol-disulfide
HGDKEKEP_03933 4.71e-122 rok - - K - - - Repressor of ComK
HGDKEKEP_03934 0.0 yclG - - M - - - Pectate lyase superfamily protein
HGDKEKEP_03935 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HGDKEKEP_03936 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HGDKEKEP_03937 6.45e-55 yclD - - - - - - -
HGDKEKEP_03938 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HGDKEKEP_03939 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HGDKEKEP_03940 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HGDKEKEP_03941 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HGDKEKEP_03942 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HGDKEKEP_03943 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HGDKEKEP_03944 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HGDKEKEP_03945 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
HGDKEKEP_03946 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HGDKEKEP_03947 0.0 ycxD - - K - - - GntR family transcriptional regulator
HGDKEKEP_03948 1.17e-198 ycxC - - EG - - - EamA-like transporter family
HGDKEKEP_03949 1.48e-122 - - - S - - - YcxB-like protein
HGDKEKEP_03950 4.92e-285 - - - EGP - - - Major Facilitator Superfamily
HGDKEKEP_03951 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HGDKEKEP_03952 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HGDKEKEP_03953 1.96e-302 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_03954 7.65e-83 yhfM - - - - - - -
HGDKEKEP_03955 9.64e-308 yhfN - - O - - - Peptidase M48
HGDKEKEP_03956 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGDKEKEP_03957 5.98e-100 - - - K - - - acetyltransferase
HGDKEKEP_03958 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HGDKEKEP_03959 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HGDKEKEP_03960 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HGDKEKEP_03961 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HGDKEKEP_03962 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HGDKEKEP_03963 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HGDKEKEP_03964 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HGDKEKEP_03965 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HGDKEKEP_03966 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HGDKEKEP_03967 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HGDKEKEP_03968 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_03969 9.84e-45 yhzC - - S - - - IDEAL
HGDKEKEP_03970 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HGDKEKEP_03971 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HGDKEKEP_03972 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
HGDKEKEP_03973 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HGDKEKEP_03974 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HGDKEKEP_03975 4.13e-78 yhjD - - - - - - -
HGDKEKEP_03976 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
HGDKEKEP_03977 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGDKEKEP_03978 0.0 yhjG - - CH - - - FAD binding domain
HGDKEKEP_03979 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGDKEKEP_03982 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HGDKEKEP_03983 9.38e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HGDKEKEP_03984 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HGDKEKEP_03985 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HGDKEKEP_03986 5.09e-238 yhjM - - K - - - Transcriptional regulator
HGDKEKEP_03987 5.04e-259 yhjN - - S ko:K07120 - ko00000 membrane
HGDKEKEP_03988 1.36e-267 - - - EGP - - - Transmembrane secretion effector
HGDKEKEP_03989 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HGDKEKEP_03990 6.29e-100 yhjR - - S - - - Rubrerythrin
HGDKEKEP_03991 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HGDKEKEP_03992 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HGDKEKEP_03993 3.84e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGDKEKEP_03994 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HGDKEKEP_03995 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
HGDKEKEP_03996 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HGDKEKEP_03997 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HGDKEKEP_03998 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HGDKEKEP_03999 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HGDKEKEP_04000 1.02e-46 gerPB - - S ko:K06300 - ko00000 cell differentiation
HGDKEKEP_04001 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HGDKEKEP_04002 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HGDKEKEP_04003 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
HGDKEKEP_04004 3.11e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HGDKEKEP_04005 1.02e-74 yisL - - S - - - UPF0344 protein
HGDKEKEP_04006 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HGDKEKEP_04008 9.46e-198 yknT - - - ko:K06437 - ko00000 -
HGDKEKEP_04009 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGDKEKEP_04010 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HGDKEKEP_04011 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HGDKEKEP_04012 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HGDKEKEP_04013 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HGDKEKEP_04014 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGDKEKEP_04015 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGDKEKEP_04016 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HGDKEKEP_04017 1.31e-150 yknW - - S - - - Yip1 domain
HGDKEKEP_04018 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGDKEKEP_04019 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_04020 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HGDKEKEP_04021 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HGDKEKEP_04022 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HGDKEKEP_04023 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HGDKEKEP_04024 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HGDKEKEP_04025 5.43e-52 ykoA - - - - - - -
HGDKEKEP_04026 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HGDKEKEP_04027 1.93e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGDKEKEP_04028 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HGDKEKEP_04029 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_04030 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_04032 1.15e-20 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HGDKEKEP_04033 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGDKEKEP_04034 4.04e-149 ydfE - - S - - - Flavin reductase like domain
HGDKEKEP_04035 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HGDKEKEP_04036 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_04037 9.99e-197 - - - EG - - - EamA-like transporter family
HGDKEKEP_04038 8.66e-186 - - - J - - - GNAT acetyltransferase
HGDKEKEP_04039 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGDKEKEP_04040 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HGDKEKEP_04041 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HGDKEKEP_04042 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
HGDKEKEP_04043 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
HGDKEKEP_04044 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HGDKEKEP_04045 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_04046 4.66e-197 ydeK - - EG - - - -transporter
HGDKEKEP_04047 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
HGDKEKEP_04048 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HGDKEKEP_04049 2.4e-41 - - - S - - - SNARE associated Golgi protein
HGDKEKEP_04050 4.95e-140 - - - - - - - -
HGDKEKEP_04051 6.35e-53 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HGDKEKEP_04052 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HGDKEKEP_04053 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGDKEKEP_04054 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HGDKEKEP_04055 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HGDKEKEP_04056 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
HGDKEKEP_04057 1.63e-39 - - - - - - - -
HGDKEKEP_04058 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HGDKEKEP_04059 3.33e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_04060 1.14e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HGDKEKEP_04061 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
HGDKEKEP_04062 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HGDKEKEP_04063 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HGDKEKEP_04064 1.05e-26 yxzF - - - - - - -
HGDKEKEP_04065 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HGDKEKEP_04066 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HGDKEKEP_04067 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGDKEKEP_04068 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_04069 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HGDKEKEP_04070 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HGDKEKEP_04071 3.56e-43 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_04072 2.19e-07 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_04073 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HGDKEKEP_04074 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGDKEKEP_04075 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_04076 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HGDKEKEP_04077 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGDKEKEP_04079 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HGDKEKEP_04084 3.09e-63 - - - S - - - dUTPase
HGDKEKEP_04090 3.33e-72 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HGDKEKEP_04091 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HGDKEKEP_04092 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HGDKEKEP_04093 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HGDKEKEP_04094 2.43e-58 yjcN - - - - - - -
HGDKEKEP_04095 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HGDKEKEP_04096 1.08e-60 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_04097 1.12e-33 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HGDKEKEP_04103 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HGDKEKEP_04104 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HGDKEKEP_04105 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
HGDKEKEP_04106 3.62e-82 cgeA - - - ko:K06319 - ko00000 -
HGDKEKEP_04107 4.45e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HGDKEKEP_04108 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HGDKEKEP_04109 5.51e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HGDKEKEP_04110 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HGDKEKEP_04111 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGDKEKEP_04112 4.14e-94 ypoP - - K - - - transcriptional
HGDKEKEP_04113 1.65e-288 mepA - - V - - - MATE efflux family protein
HGDKEKEP_04114 1.24e-39 ypmT - - S - - - Uncharacterized ympT
HGDKEKEP_04115 4.59e-127 ypmS - - S - - - protein conserved in bacteria
HGDKEKEP_04116 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HGDKEKEP_04117 1.24e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HGDKEKEP_04118 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
HGDKEKEP_04119 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGDKEKEP_04120 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HGDKEKEP_04121 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HGDKEKEP_04122 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
HGDKEKEP_04123 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGDKEKEP_04124 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGDKEKEP_04125 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HGDKEKEP_04126 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGDKEKEP_04127 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HGDKEKEP_04128 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HGDKEKEP_04130 1.23e-242 - - - I - - - Pfam Lipase (class 3)
HGDKEKEP_04131 9.96e-22 - - - - - - - -
HGDKEKEP_04132 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HGDKEKEP_04133 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HGDKEKEP_04134 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HGDKEKEP_04135 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGDKEKEP_04136 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGDKEKEP_04137 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HGDKEKEP_04139 3.17e-170 - - - L - - - Phage integrase family
HGDKEKEP_04142 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HGDKEKEP_04143 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
HGDKEKEP_04144 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HGDKEKEP_04145 3.84e-87 res - - L - - - Resolvase, N terminal domain
HGDKEKEP_04146 2.61e-15 - - - S - - - Protein of unknown function (DUF1433)
HGDKEKEP_04147 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
HGDKEKEP_04149 3.24e-93 - - - S - - - CAAX protease self-immunity
HGDKEKEP_04150 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGDKEKEP_04151 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HGDKEKEP_04152 1.6e-08 - - - S - - - Domain of unknown function (DUF3885)
HGDKEKEP_04153 1.9e-102 - - - S - - - Domain of unknown function (DUF3885)
HGDKEKEP_04154 4.19e-20 ynaF - - - - - - -
HGDKEKEP_04156 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
HGDKEKEP_04157 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HGDKEKEP_04158 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HGDKEKEP_04159 6.82e-273 xylR - - GK - - - ROK family
HGDKEKEP_04160 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HGDKEKEP_04161 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HGDKEKEP_04164 2.66e-120 yebE - - S - - - UPF0316 protein
HGDKEKEP_04165 3.13e-38 yebG - - S - - - NETI protein
HGDKEKEP_04166 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGDKEKEP_04167 1.24e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGDKEKEP_04168 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGDKEKEP_04169 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HGDKEKEP_04170 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGDKEKEP_04171 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGDKEKEP_04172 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGDKEKEP_04173 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGDKEKEP_04174 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HGDKEKEP_04175 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGDKEKEP_04176 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HGDKEKEP_04177 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HGDKEKEP_04178 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HGDKEKEP_04179 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
HGDKEKEP_04180 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HGDKEKEP_04181 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HGDKEKEP_04182 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HGDKEKEP_04183 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGDKEKEP_04184 9.26e-10 - - - S - - - Fur-regulated basic protein B
HGDKEKEP_04186 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HGDKEKEP_04187 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HGDKEKEP_04188 3.3e-71 yneQ - - - - - - -
HGDKEKEP_04190 5.08e-26 xkdM - - S - - - Phage tail tube protein
HGDKEKEP_04191 2.43e-14 - - - - - - - -
HGDKEKEP_04194 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
HGDKEKEP_04197 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HGDKEKEP_04198 1.08e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HGDKEKEP_04199 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HGDKEKEP_04200 1.8e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGDKEKEP_04201 2.44e-210 - - - K - - - AraC-like ligand binding domain
HGDKEKEP_04202 2.27e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HGDKEKEP_04203 8.94e-90 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HGDKEKEP_04204 6.37e-103 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HGDKEKEP_04205 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HGDKEKEP_04206 1.34e-196 ydeG - - EGP - - - Major facilitator superfamily
HGDKEKEP_04207 4.72e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HGDKEKEP_04209 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGDKEKEP_04210 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HGDKEKEP_04211 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGDKEKEP_04212 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGDKEKEP_04213 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HGDKEKEP_04214 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HGDKEKEP_04215 6.01e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HGDKEKEP_04216 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HGDKEKEP_04217 3.2e-265 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HGDKEKEP_04218 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
HGDKEKEP_04219 1.33e-160 ynaC - - - - - - -
HGDKEKEP_04220 8.25e-61 - - - S - - - Restriction endonuclease
HGDKEKEP_04221 7.12e-37 - - - - - - - -
HGDKEKEP_04222 1.14e-20 - - - S - - - peptidoglycan catabolic process
HGDKEKEP_04223 3.5e-35 - - - K - - - Helix-turn-helix domain
HGDKEKEP_04224 2.45e-34 - - - K - - - Helix-turn-helix domain
HGDKEKEP_04225 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
HGDKEKEP_04226 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HGDKEKEP_04227 6.89e-58 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HGDKEKEP_04228 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
HGDKEKEP_04229 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HGDKEKEP_04230 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HGDKEKEP_04231 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGDKEKEP_04233 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGDKEKEP_04234 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HGDKEKEP_04235 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HGDKEKEP_04236 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HGDKEKEP_04237 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HGDKEKEP_04238 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HGDKEKEP_04239 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HGDKEKEP_04241 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_04242 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HGDKEKEP_04243 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HGDKEKEP_04244 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HGDKEKEP_04245 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGDKEKEP_04246 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGDKEKEP_04247 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGDKEKEP_04248 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGDKEKEP_04249 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HGDKEKEP_04250 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HGDKEKEP_04251 1.42e-21 - - - - - - - -
HGDKEKEP_04252 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HGDKEKEP_04253 1.15e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGDKEKEP_04254 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HGDKEKEP_04255 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HGDKEKEP_04256 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HGDKEKEP_04257 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HGDKEKEP_04258 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HGDKEKEP_04259 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HGDKEKEP_04260 1.92e-97 yuxK - - S - - - protein conserved in bacteria
HGDKEKEP_04261 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HGDKEKEP_04262 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
HGDKEKEP_04264 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HGDKEKEP_04265 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HGDKEKEP_04266 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HGDKEKEP_04267 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HGDKEKEP_04268 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HGDKEKEP_04269 3.43e-71 yugF - - I - - - Hydrolase
HGDKEKEP_04270 0.0 rocB - - E - - - arginine degradation protein
HGDKEKEP_04271 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HGDKEKEP_04272 2.45e-23 - - - S - - - YrzO-like protein
HGDKEKEP_04273 3.17e-212 yrdR - - EG - - - EamA-like transporter family
HGDKEKEP_04274 1.4e-203 - - - K - - - Transcriptional regulator
HGDKEKEP_04275 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HGDKEKEP_04276 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HGDKEKEP_04283 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGDKEKEP_04284 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HGDKEKEP_04285 2.51e-13 - - - - - - - -
HGDKEKEP_04287 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HGDKEKEP_04288 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HGDKEKEP_04289 9.04e-46 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HGDKEKEP_04290 8.04e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGDKEKEP_04291 3.25e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HGDKEKEP_04292 8.23e-112 yteJ - - S - - - RDD family
HGDKEKEP_04293 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
HGDKEKEP_04294 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
HGDKEKEP_04295 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGDKEKEP_04296 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HGDKEKEP_04298 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGDKEKEP_04299 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HGDKEKEP_04300 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGDKEKEP_04301 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HGDKEKEP_04303 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HGDKEKEP_04304 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HGDKEKEP_04305 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HGDKEKEP_04306 2.15e-63 ytpI - - S - - - YtpI-like protein
HGDKEKEP_04307 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HGDKEKEP_04308 1.15e-39 - - - - - - - -
HGDKEKEP_04309 5.12e-112 ytrI - - - - - - -
HGDKEKEP_04310 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HGDKEKEP_04311 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HGDKEKEP_04312 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HGDKEKEP_04313 5.96e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGDKEKEP_04314 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HGDKEKEP_04315 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HGDKEKEP_04316 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HGDKEKEP_04317 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HGDKEKEP_04318 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
HGDKEKEP_04319 9.38e-95 ytwI - - S - - - membrane
HGDKEKEP_04320 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
HGDKEKEP_04321 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_04322 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGDKEKEP_04323 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HGDKEKEP_04324 2.82e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_04325 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HGDKEKEP_04326 9.48e-193 yjaZ - - O - - - Zn-dependent protease
HGDKEKEP_04327 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGDKEKEP_04328 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGDKEKEP_04329 2.67e-38 yjzB - - - - - - -
HGDKEKEP_04330 8.86e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HGDKEKEP_04331 5.26e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HGDKEKEP_04332 5.2e-132 yjaV - - - - - - -
HGDKEKEP_04333 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
HGDKEKEP_04334 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HGDKEKEP_04335 2.51e-39 yjzC - - S - - - YjzC-like protein
HGDKEKEP_04336 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HGDKEKEP_04337 1.58e-36 - - - - - - - -
HGDKEKEP_04338 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HGDKEKEP_04339 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGDKEKEP_04342 1.12e-07 - - - S - - - YopX protein
HGDKEKEP_04344 1.76e-59 - - - S - - - dUTPase
HGDKEKEP_04350 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HGDKEKEP_04351 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HGDKEKEP_04352 5.71e-121 - - - M - - - FR47-like protein
HGDKEKEP_04353 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HGDKEKEP_04354 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HGDKEKEP_04355 6.53e-108 yuaE - - S - - - DinB superfamily
HGDKEKEP_04356 5.85e-164 - - - - - - - -
HGDKEKEP_04357 2e-169 - - - - - - - -
HGDKEKEP_04358 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HGDKEKEP_04359 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HGDKEKEP_04360 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
HGDKEKEP_04361 0.0 - - - O - - - Peptidase family M48
HGDKEKEP_04363 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
HGDKEKEP_04364 2.29e-29 ywtC - - - - - - -
HGDKEKEP_04365 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HGDKEKEP_04366 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HGDKEKEP_04367 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HGDKEKEP_04368 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGDKEKEP_04369 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGDKEKEP_04370 8.71e-176 yphF - - - - - - -
HGDKEKEP_04371 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
HGDKEKEP_04372 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HGDKEKEP_04373 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HGDKEKEP_04374 2.06e-38 ypzH - - - - - - -
HGDKEKEP_04375 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HGDKEKEP_04376 1.11e-133 yphA - - - - - - -
HGDKEKEP_04377 1.13e-11 - - - S - - - YpzI-like protein
HGDKEKEP_04378 4.82e-69 ynaF - - - - - - -
HGDKEKEP_04380 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HGDKEKEP_04382 0.0 - - - V - - - Beta-lactamase
HGDKEKEP_04385 2.63e-11 - - - - - - - -
HGDKEKEP_04386 1e-89 - - - S - - - Phage terminase, small subunit
HGDKEKEP_04387 5.52e-100 papA4 - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 synthase
HGDKEKEP_04390 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
HGDKEKEP_04391 3.86e-10 - - - S - - - Family of unknown function (DUF5316)
HGDKEKEP_04393 8.21e-15 - - - K - - - Transcriptional regulator
HGDKEKEP_04394 1.37e-144 papA4 - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 synthase
HGDKEKEP_04395 2.71e-103 yjoA - - S - - - DinB family
HGDKEKEP_04396 2.47e-268 VCP - - O - - - AAA domain (dynein-related subfamily)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)