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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IFMEFEAN_00001	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IFMEFEAN_00002	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IFMEFEAN_00003	8.71e-176	yphF	-	-	-	-	-	-	-
IFMEFEAN_00004	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IFMEFEAN_00005	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IFMEFEAN_00006	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IFMEFEAN_00007	2.06e-38	ypzH	-	-	-	-	-	-	-
IFMEFEAN_00008	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
IFMEFEAN_00009	1.11e-133	yphA	-	-	-	-	-	-	-
IFMEFEAN_00010	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
IFMEFEAN_00011	3.07e-27	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00023	5.86e-29	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	PFAM Type II secretion system protein E
IFMEFEAN_00026	8.35e-11	-	-	-	M	-	-	-	NlpC P60 family protein
IFMEFEAN_00036	1.63e-06	-	-	-	S	-	-	-	SEC-C motif
IFMEFEAN_00037	1.38e-56	-	-	-	L	-	-	-	Initiator Replication protein
IFMEFEAN_00038	3.19e-42	-	-	-	-	-	-	-	-
IFMEFEAN_00039	1.09e-199	-	-	-	S	-	-	-	Domain of unknown function (DUF5068)
IFMEFEAN_00040	5.07e-20	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00041	1e-12	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00047	1.25e-77	-	-	-	-	-	-	-	-
IFMEFEAN_00056	0.00014	-	-	-	K	-	-	-	XRE family transcriptional regulator
IFMEFEAN_00059	3.64e-10	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IFMEFEAN_00060	8.62e-13	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00061	5.8e-08	-	-	-	-	-	-	-	-
IFMEFEAN_00064	7.17e-18	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein CoiA-like family
IFMEFEAN_00066	9.56e-80	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IFMEFEAN_00067	1.87e-218	-	-	-	L	-	-	-	TIGRFAM Transposase, IS605 OrfB, C-terminal
IFMEFEAN_00076	2.22e-53	-	-	-	-	-	-	-	-
IFMEFEAN_00086	5.23e-85	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMEFEAN_00087	2.75e-96	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
IFMEFEAN_00100	1.26e-113	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_00107	6.11e-23	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IFMEFEAN_00108	1.92e-19	-	-	-	V	-	-	-	VanZ like family
IFMEFEAN_00110	1.96e-17	-	-	-	-	-	-	-	-
IFMEFEAN_00111	1.09e-64	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	COG1191 DNA-directed RNA polymerase specialized sigma subunit
IFMEFEAN_00112	1.25e-13	-	-	-	S	-	-	-	YvrJ protein family
IFMEFEAN_00114	4.64e-10	-	-	-	-	-	-	-	-
IFMEFEAN_00120	1.24e-21	-	-	-	-	-	-	-	-
IFMEFEAN_00121	7.26e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_00124	9.03e-142	-	-	-	V	ko:K06877,ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IFMEFEAN_00127	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IFMEFEAN_00128	7.21e-262	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IFMEFEAN_00129	1.7e-73	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IFMEFEAN_00130	5.88e-38	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IFMEFEAN_00131	2.55e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IFMEFEAN_00132	1.59e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IFMEFEAN_00133	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IFMEFEAN_00134	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IFMEFEAN_00135	1.07e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IFMEFEAN_00136	9.83e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00137	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IFMEFEAN_00138	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IFMEFEAN_00139	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IFMEFEAN_00141	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFMEFEAN_00142	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IFMEFEAN_00143	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IFMEFEAN_00144	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IFMEFEAN_00145	2.58e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IFMEFEAN_00146	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IFMEFEAN_00147	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IFMEFEAN_00148	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IFMEFEAN_00149	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IFMEFEAN_00150	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IFMEFEAN_00151	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IFMEFEAN_00152	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IFMEFEAN_00153	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IFMEFEAN_00154	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IFMEFEAN_00155	7.25e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFMEFEAN_00156	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IFMEFEAN_00157	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IFMEFEAN_00158	4.89e-63	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IFMEFEAN_00159	4.88e-29	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IFMEFEAN_00160	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IFMEFEAN_00161	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
IFMEFEAN_00162	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IFMEFEAN_00163	3.05e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IFMEFEAN_00164	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IFMEFEAN_00165	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
IFMEFEAN_00166	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
IFMEFEAN_00167	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IFMEFEAN_00168	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IFMEFEAN_00169	9.92e-212	ytlQ	-	-	-	-	-	-	-
IFMEFEAN_00170	1.5e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IFMEFEAN_00171	6.05e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IFMEFEAN_00172	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IFMEFEAN_00173	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IFMEFEAN_00174	1.12e-252	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IFMEFEAN_00175	8.04e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IFMEFEAN_00176	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IFMEFEAN_00177	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IFMEFEAN_00178	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_00179	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IFMEFEAN_00180	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IFMEFEAN_00181	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IFMEFEAN_00183	6.02e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IFMEFEAN_00184	9.64e-94	yteS	-	-	G	-	-	-	transport
IFMEFEAN_00185	8.3e-279	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IFMEFEAN_00186	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IFMEFEAN_00187	1.36e-202	ytdP	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00188	2.13e-75	ytdP	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00189	1.13e-165	ytdP	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00190	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IFMEFEAN_00191	1.19e-190	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IFMEFEAN_00192	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
IFMEFEAN_00193	2.6e-278	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IFMEFEAN_00194	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IFMEFEAN_00195	2.68e-159	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IFMEFEAN_00196	4.1e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IFMEFEAN_00197	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IFMEFEAN_00198	3.63e-151	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IFMEFEAN_00199	4.8e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
IFMEFEAN_00200	4.37e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00201	7.92e-307	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMEFEAN_00202	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_00203	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IFMEFEAN_00204	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IFMEFEAN_00205	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IFMEFEAN_00206	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IFMEFEAN_00207	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IFMEFEAN_00208	3.82e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IFMEFEAN_00209	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IFMEFEAN_00210	5.71e-41	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IFMEFEAN_00211	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IFMEFEAN_00212	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00213	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IFMEFEAN_00214	2.23e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_00215	3.99e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IFMEFEAN_00216	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00217	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IFMEFEAN_00218	4.46e-211	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_00219	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00220	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IFMEFEAN_00222	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IFMEFEAN_00223	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IFMEFEAN_00224	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IFMEFEAN_00225	2.78e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IFMEFEAN_00226	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IFMEFEAN_00227	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IFMEFEAN_00228	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_00229	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IFMEFEAN_00230	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IFMEFEAN_00231	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IFMEFEAN_00232	5.75e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IFMEFEAN_00233	9.48e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IFMEFEAN_00234	7.95e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IFMEFEAN_00235	6.12e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMEFEAN_00236	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IFMEFEAN_00237	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IFMEFEAN_00238	1.52e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IFMEFEAN_00239	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IFMEFEAN_00241	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
IFMEFEAN_00242	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IFMEFEAN_00243	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IFMEFEAN_00244	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IFMEFEAN_00245	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IFMEFEAN_00246	1.64e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IFMEFEAN_00247	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IFMEFEAN_00248	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IFMEFEAN_00249	3.85e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IFMEFEAN_00250	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IFMEFEAN_00251	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFMEFEAN_00252	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IFMEFEAN_00253	1.04e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IFMEFEAN_00254	4.86e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IFMEFEAN_00255	3.76e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IFMEFEAN_00256	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IFMEFEAN_00257	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IFMEFEAN_00258	4.97e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IFMEFEAN_00259	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IFMEFEAN_00260	3e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IFMEFEAN_00261	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IFMEFEAN_00262	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IFMEFEAN_00263	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IFMEFEAN_00264	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IFMEFEAN_00265	6.89e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IFMEFEAN_00266	2.06e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IFMEFEAN_00267	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IFMEFEAN_00268	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IFMEFEAN_00269	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IFMEFEAN_00270	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
IFMEFEAN_00271	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IFMEFEAN_00272	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IFMEFEAN_00273	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IFMEFEAN_00274	5.13e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IFMEFEAN_00275	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IFMEFEAN_00276	7.97e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IFMEFEAN_00277	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IFMEFEAN_00278	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IFMEFEAN_00279	2.07e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IFMEFEAN_00280	1.38e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IFMEFEAN_00281	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IFMEFEAN_00282	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IFMEFEAN_00283	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IFMEFEAN_00284	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IFMEFEAN_00285	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IFMEFEAN_00286	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00287	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IFMEFEAN_00288	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IFMEFEAN_00289	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IFMEFEAN_00290	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IFMEFEAN_00291	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IFMEFEAN_00292	1.68e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IFMEFEAN_00293	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IFMEFEAN_00294	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IFMEFEAN_00295	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IFMEFEAN_00296	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IFMEFEAN_00297	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IFMEFEAN_00298	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IFMEFEAN_00299	1.67e-114	-	-	-	-	-	-	-	-
IFMEFEAN_00300	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IFMEFEAN_00301	1.13e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IFMEFEAN_00302	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IFMEFEAN_00303	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IFMEFEAN_00304	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
IFMEFEAN_00305	7.5e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IFMEFEAN_00306	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IFMEFEAN_00307	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IFMEFEAN_00308	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IFMEFEAN_00309	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFMEFEAN_00310	0.0	ylqG	-	-	-	-	-	-	-
IFMEFEAN_00311	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IFMEFEAN_00312	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IFMEFEAN_00313	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IFMEFEAN_00314	3.48e-213	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IFMEFEAN_00315	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IFMEFEAN_00316	2.22e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IFMEFEAN_00317	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IFMEFEAN_00318	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IFMEFEAN_00319	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IFMEFEAN_00320	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IFMEFEAN_00321	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IFMEFEAN_00322	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IFMEFEAN_00323	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IFMEFEAN_00324	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IFMEFEAN_00325	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IFMEFEAN_00326	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IFMEFEAN_00327	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IFMEFEAN_00328	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IFMEFEAN_00329	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IFMEFEAN_00330	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IFMEFEAN_00331	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IFMEFEAN_00332	3.12e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IFMEFEAN_00333	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IFMEFEAN_00334	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IFMEFEAN_00335	1.6e-252	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IFMEFEAN_00336	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IFMEFEAN_00337	3.99e-130	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IFMEFEAN_00338	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IFMEFEAN_00339	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IFMEFEAN_00340	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IFMEFEAN_00341	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IFMEFEAN_00342	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IFMEFEAN_00343	8.03e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IFMEFEAN_00344	1.81e-199	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IFMEFEAN_00345	1.49e-251	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IFMEFEAN_00346	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IFMEFEAN_00347	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IFMEFEAN_00348	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IFMEFEAN_00349	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IFMEFEAN_00350	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_00351	6.91e-101	ylxL	-	-	-	-	-	-	-
IFMEFEAN_00352	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IFMEFEAN_00353	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IFMEFEAN_00354	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IFMEFEAN_00355	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IFMEFEAN_00356	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IFMEFEAN_00357	4.74e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IFMEFEAN_00358	1.14e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IFMEFEAN_00359	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IFMEFEAN_00360	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IFMEFEAN_00361	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFMEFEAN_00362	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IFMEFEAN_00363	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IFMEFEAN_00364	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IFMEFEAN_00365	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IFMEFEAN_00366	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IFMEFEAN_00367	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IFMEFEAN_00368	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IFMEFEAN_00369	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IFMEFEAN_00370	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IFMEFEAN_00371	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IFMEFEAN_00372	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IFMEFEAN_00373	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IFMEFEAN_00374	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IFMEFEAN_00375	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IFMEFEAN_00376	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IFMEFEAN_00377	1.36e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IFMEFEAN_00378	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IFMEFEAN_00379	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IFMEFEAN_00380	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IFMEFEAN_00381	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFMEFEAN_00382	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IFMEFEAN_00383	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
IFMEFEAN_00384	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IFMEFEAN_00385	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00386	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_00387	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
IFMEFEAN_00388	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
IFMEFEAN_00389	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IFMEFEAN_00390	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IFMEFEAN_00391	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IFMEFEAN_00392	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IFMEFEAN_00393	1.36e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IFMEFEAN_00394	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IFMEFEAN_00395	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IFMEFEAN_00396	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
IFMEFEAN_00397	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IFMEFEAN_00398	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IFMEFEAN_00399	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IFMEFEAN_00400	1.96e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IFMEFEAN_00401	1.62e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IFMEFEAN_00402	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IFMEFEAN_00403	1.32e-272	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IFMEFEAN_00404	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IFMEFEAN_00405	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IFMEFEAN_00406	1.9e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IFMEFEAN_00407	9.41e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_00408	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_00409	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IFMEFEAN_00410	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IFMEFEAN_00411	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IFMEFEAN_00412	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IFMEFEAN_00413	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IFMEFEAN_00414	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IFMEFEAN_00415	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IFMEFEAN_00416	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IFMEFEAN_00417	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IFMEFEAN_00418	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IFMEFEAN_00419	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IFMEFEAN_00420	1.25e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IFMEFEAN_00421	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMEFEAN_00422	7.05e-124	yhcQ	-	-	M	-	-	-	Spore coat protein
IFMEFEAN_00423	3.38e-216	yhcP	-	-	-	-	-	-	-
IFMEFEAN_00424	9.32e-108	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IFMEFEAN_00425	9.39e-63	yhcM	-	-	-	-	-	-	-
IFMEFEAN_00427	2.45e-83	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_00428	2.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
IFMEFEAN_00429	3.04e-87	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
IFMEFEAN_00430	3.19e-111	yddI	-	-	-	-	-	-	-
IFMEFEAN_00431	1.03e-237	yddH	-	-	M	-	-	-	Lysozyme-like
IFMEFEAN_00432	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
IFMEFEAN_00433	1.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
IFMEFEAN_00434	2.21e-242	yddE	-	-	S	-	-	-	AAA-like domain
IFMEFEAN_00435	1.59e-270	yddE	-	-	S	-	-	-	AAA-like domain
IFMEFEAN_00436	6.91e-118	yddD	-	-	S	-	-	-	TcpE family
IFMEFEAN_00437	9.78e-54	yddC	-	-	-	-	-	-	-
IFMEFEAN_00438	2.61e-223	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
IFMEFEAN_00442	4.39e-37	yddA	-	-	-	-	-	-	-
IFMEFEAN_00444	6.72e-60	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_00448	1.5e-81	-	-	-	S	-	-	-	Immunity protein 70
IFMEFEAN_00449	1.08e-219	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IFMEFEAN_00450	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IFMEFEAN_00451	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IFMEFEAN_00452	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IFMEFEAN_00453	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IFMEFEAN_00454	5.71e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IFMEFEAN_00455	5.09e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00456	1.32e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00457	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00458	2.06e-69	-	-	-	-	-	-	-	-
IFMEFEAN_00459	3.95e-59	yhcC	-	-	-	-	-	-	-
IFMEFEAN_00460	1.4e-127	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
IFMEFEAN_00461	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IFMEFEAN_00462	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IFMEFEAN_00463	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IFMEFEAN_00464	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IFMEFEAN_00465	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IFMEFEAN_00466	3.01e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IFMEFEAN_00467	1.53e-94	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IFMEFEAN_00468	3.97e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IFMEFEAN_00469	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IFMEFEAN_00470	9.27e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
IFMEFEAN_00471	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IFMEFEAN_00472	1.07e-144	yhzB	-	-	S	-	-	-	B3/4 domain
IFMEFEAN_00474	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00475	6.32e-99	ygaO	-	-	-	-	-	-	-
IFMEFEAN_00476	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFMEFEAN_00479	8.96e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IFMEFEAN_00480	4.62e-187	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IFMEFEAN_00481	2.79e-213	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IFMEFEAN_00482	7.4e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IFMEFEAN_00483	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IFMEFEAN_00484	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
IFMEFEAN_00486	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IFMEFEAN_00487	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IFMEFEAN_00488	2.56e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IFMEFEAN_00490	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
IFMEFEAN_00491	1.17e-137	yfhC	-	-	C	-	-	-	nitroreductase
IFMEFEAN_00492	9.95e-211	yfhB	-	-	S	-	-	-	PhzF family
IFMEFEAN_00493	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00494	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00495	1.28e-229	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMEFEAN_00496	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IFMEFEAN_00497	4.26e-103	yfiV	-	-	K	-	-	-	transcriptional
IFMEFEAN_00498	7.8e-22	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IFMEFEAN_00499	1.11e-291	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IFMEFEAN_00500	4.67e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IFMEFEAN_00501	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
IFMEFEAN_00502	4.01e-139	yfiR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00503	2.68e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IFMEFEAN_00504	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IFMEFEAN_00505	1.89e-128	padR	-	-	K	-	-	-	transcriptional
IFMEFEAN_00506	3.44e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IFMEFEAN_00507	5.69e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_00508	1.78e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00509	5.82e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
IFMEFEAN_00510	1.7e-272	baeS	-	-	T	-	-	-	Histidine kinase
IFMEFEAN_00512	2.97e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IFMEFEAN_00513	1.93e-82	yfiD3	-	-	S	-	-	-	DoxX
IFMEFEAN_00514	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IFMEFEAN_00515	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IFMEFEAN_00516	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_00517	1.23e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IFMEFEAN_00518	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IFMEFEAN_00519	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
IFMEFEAN_00520	1.94e-270	yfjB	-	-	-	-	-	-	-
IFMEFEAN_00521	1.02e-184	yfjC	-	-	-	-	-	-	-
IFMEFEAN_00522	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
IFMEFEAN_00523	1e-105	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
IFMEFEAN_00524	2.9e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
IFMEFEAN_00525	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IFMEFEAN_00526	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IFMEFEAN_00527	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IFMEFEAN_00528	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IFMEFEAN_00529	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IFMEFEAN_00530	6.48e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IFMEFEAN_00532	7.85e-110	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IFMEFEAN_00533	1.25e-236	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IFMEFEAN_00534	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
IFMEFEAN_00535	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFMEFEAN_00536	3.92e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IFMEFEAN_00537	1.24e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IFMEFEAN_00538	2.29e-192	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IFMEFEAN_00539	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IFMEFEAN_00540	3.26e-36	yfjT	-	-	-	-	-	-	-
IFMEFEAN_00541	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
IFMEFEAN_00542	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IFMEFEAN_00543	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
IFMEFEAN_00544	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IFMEFEAN_00545	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_00546	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IFMEFEAN_00547	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
IFMEFEAN_00548	5.89e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IFMEFEAN_00549	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IFMEFEAN_00550	6.93e-263	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_00551	1.83e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IFMEFEAN_00552	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMEFEAN_00553	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
IFMEFEAN_00554	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IFMEFEAN_00555	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IFMEFEAN_00556	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_00557	1.43e-41	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IFMEFEAN_00558	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IFMEFEAN_00559	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IFMEFEAN_00560	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IFMEFEAN_00561	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IFMEFEAN_00562	1.73e-64	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IFMEFEAN_00563	6.9e-27	yflI	-	-	-	-	-	-	-
IFMEFEAN_00564	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IFMEFEAN_00565	3.28e-155	yflK	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00566	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IFMEFEAN_00567	4.6e-274	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IFMEFEAN_00568	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IFMEFEAN_00569	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IFMEFEAN_00570	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IFMEFEAN_00571	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IFMEFEAN_00572	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IFMEFEAN_00573	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IFMEFEAN_00574	1.16e-305	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IFMEFEAN_00575	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IFMEFEAN_00576	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IFMEFEAN_00577	1.94e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IFMEFEAN_00578	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00579	2.98e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00580	1.15e-191	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IFMEFEAN_00581	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IFMEFEAN_00582	0.0	-	-	-	IQ	ko:K15641,ko:K16398,ko:K16417,ko:K20788	ko01052,map01052	ko00000,ko00001,ko01008	PKS_KR
IFMEFEAN_00583	1.98e-56	-	-	-	S	-	-	-	MepB protein
IFMEFEAN_00584	8.33e-58	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IFMEFEAN_00585	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IFMEFEAN_00586	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
IFMEFEAN_00587	1.34e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
IFMEFEAN_00588	5.59e-64	-	-	-	-	-	-	-	-
IFMEFEAN_00589	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IFMEFEAN_00590	1.55e-65	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
IFMEFEAN_00591	1.89e-70	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
IFMEFEAN_00592	2.05e-131	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
IFMEFEAN_00594	1.96e-178	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IFMEFEAN_00595	1.49e-192	ybdN	-	-	-	-	-	-	-
IFMEFEAN_00596	4.65e-276	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
IFMEFEAN_00597	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_00598	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IFMEFEAN_00599	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
IFMEFEAN_00600	1.76e-166	-	-	-	T	-	-	-	Signal transduction histidine kinase
IFMEFEAN_00601	8.24e-73	-	-	-	T	-	-	-	Signal transduction histidine kinase
IFMEFEAN_00602	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
IFMEFEAN_00603	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IFMEFEAN_00605	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
IFMEFEAN_00606	2.13e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IFMEFEAN_00607	2.21e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IFMEFEAN_00608	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IFMEFEAN_00609	1.69e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IFMEFEAN_00610	6.6e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IFMEFEAN_00611	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
IFMEFEAN_00612	9.07e-197	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IFMEFEAN_00613	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IFMEFEAN_00614	1.51e-91	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IFMEFEAN_00615	2.28e-63	yxiS	-	-	-	-	-	-	-
IFMEFEAN_00616	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IFMEFEAN_00617	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IFMEFEAN_00618	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
IFMEFEAN_00619	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IFMEFEAN_00620	7.23e-141	-	-	-	-	-	-	-	-
IFMEFEAN_00621	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IFMEFEAN_00622	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IFMEFEAN_00623	3.52e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMEFEAN_00626	4.06e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IFMEFEAN_00629	1.86e-40	-	-	-	-	-	-	-	-
IFMEFEAN_00630	8.21e-50	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
IFMEFEAN_00631	3.42e-173	-	-	-	-	-	-	-	-
IFMEFEAN_00634	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
IFMEFEAN_00635	9.7e-68	yxxG	-	-	-	-	-	-	-
IFMEFEAN_00636	4.67e-89	yxiG	-	-	-	-	-	-	-
IFMEFEAN_00637	4.48e-58	-	-	-	-	-	-	-	-
IFMEFEAN_00638	7.13e-100	-	-	-	-	-	-	-	-
IFMEFEAN_00639	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
IFMEFEAN_00640	5.06e-175	-	-	-	-	-	-	-	-
IFMEFEAN_00642	1.27e-69	-	-	-	-	-	-	-	-
IFMEFEAN_00643	6.47e-100	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IFMEFEAN_00644	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IFMEFEAN_00645	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IFMEFEAN_00646	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_00647	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_00648	4.54e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
IFMEFEAN_00649	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IFMEFEAN_00650	8.86e-317	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMEFEAN_00651	1.56e-53	-	-	-	-	-	-	-	-
IFMEFEAN_00652	5.35e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
IFMEFEAN_00653	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
IFMEFEAN_00654	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
IFMEFEAN_00655	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
IFMEFEAN_00656	0.0	-	-	-	L	-	-	-	HKD family nuclease
IFMEFEAN_00657	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IFMEFEAN_00658	2.01e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
IFMEFEAN_00659	1.49e-308	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IFMEFEAN_00660	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IFMEFEAN_00661	2.24e-204	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IFMEFEAN_00662	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IFMEFEAN_00663	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IFMEFEAN_00664	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IFMEFEAN_00665	7.06e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IFMEFEAN_00666	8.39e-194	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
IFMEFEAN_00667	2.99e-249	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
IFMEFEAN_00668	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IFMEFEAN_00669	4.78e-271	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IFMEFEAN_00670	6.82e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00671	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IFMEFEAN_00672	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IFMEFEAN_00673	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_00674	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFMEFEAN_00675	4.03e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IFMEFEAN_00676	3.29e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IFMEFEAN_00679	5.99e-41	yxeE	-	-	-	-	-	-	-
IFMEFEAN_00680	7.57e-28	yxeD	-	-	-	-	-	-	-
IFMEFEAN_00681	9.65e-91	-	-	-	-	-	-	-	-
IFMEFEAN_00682	1.55e-215	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_00683	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IFMEFEAN_00684	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IFMEFEAN_00685	8.64e-178	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_00686	1.75e-227	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_00687	9.37e-159	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_00688	3.3e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IFMEFEAN_00689	2.29e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IFMEFEAN_00690	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IFMEFEAN_00691	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IFMEFEAN_00692	1.34e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IFMEFEAN_00693	4.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IFMEFEAN_00694	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IFMEFEAN_00695	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IFMEFEAN_00696	2.43e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IFMEFEAN_00697	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IFMEFEAN_00698	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IFMEFEAN_00699	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IFMEFEAN_00700	7.27e-55	-	-	-	-	-	-	-	-
IFMEFEAN_00702	2.23e-17	-	-	-	S	-	-	-	CGNR zinc finger
IFMEFEAN_00703	1.05e-101	-	-	-	T	-	-	-	HPP family
IFMEFEAN_00704	2.22e-38	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_00705	2.4e-233	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_00706	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IFMEFEAN_00708	9.3e-23	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IFMEFEAN_00709	2.01e-156	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IFMEFEAN_00710	6.97e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMEFEAN_00711	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IFMEFEAN_00712	2.54e-43	yxaI	-	-	S	-	-	-	membrane protein domain
IFMEFEAN_00713	7.97e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IFMEFEAN_00714	1.35e-97	yxaI	-	-	S	-	-	-	membrane protein domain
IFMEFEAN_00715	1.46e-283	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IFMEFEAN_00716	5.18e-251	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IFMEFEAN_00717	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IFMEFEAN_00718	2.49e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_00719	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IFMEFEAN_00720	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IFMEFEAN_00721	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IFMEFEAN_00722	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IFMEFEAN_00723	2e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IFMEFEAN_00724	1.27e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
IFMEFEAN_00725	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IFMEFEAN_00726	1.18e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IFMEFEAN_00727	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IFMEFEAN_00728	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IFMEFEAN_00729	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IFMEFEAN_00730	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMEFEAN_00731	4.15e-14	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_00732	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_00733	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_00734	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_00735	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IFMEFEAN_00736	9.06e-47	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
IFMEFEAN_00737	1.66e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
IFMEFEAN_00738	6.92e-17	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IFMEFEAN_00739	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IFMEFEAN_00740	6.08e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IFMEFEAN_00741	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IFMEFEAN_00742	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IFMEFEAN_00743	4.67e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IFMEFEAN_00744	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00745	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IFMEFEAN_00746	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IFMEFEAN_00747	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IFMEFEAN_00748	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IFMEFEAN_00749	4.66e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IFMEFEAN_00750	2.84e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IFMEFEAN_00751	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IFMEFEAN_00752	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IFMEFEAN_00753	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IFMEFEAN_00754	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IFMEFEAN_00755	1.18e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
IFMEFEAN_00756	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IFMEFEAN_00757	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IFMEFEAN_00758	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IFMEFEAN_00759	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00760	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
IFMEFEAN_00761	9.53e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IFMEFEAN_00762	3.82e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IFMEFEAN_00763	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IFMEFEAN_00764	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IFMEFEAN_00765	1.49e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IFMEFEAN_00766	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFMEFEAN_00767	1.69e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IFMEFEAN_00768	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IFMEFEAN_00769	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IFMEFEAN_00770	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IFMEFEAN_00771	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IFMEFEAN_00772	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_00773	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IFMEFEAN_00774	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IFMEFEAN_00775	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
IFMEFEAN_00776	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IFMEFEAN_00777	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IFMEFEAN_00778	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IFMEFEAN_00781	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IFMEFEAN_00782	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IFMEFEAN_00783	6.63e-234	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IFMEFEAN_00784	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IFMEFEAN_00785	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IFMEFEAN_00786	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IFMEFEAN_00787	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IFMEFEAN_00788	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IFMEFEAN_00789	2.41e-204	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IFMEFEAN_00790	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IFMEFEAN_00791	2.45e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IFMEFEAN_00792	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_00793	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IFMEFEAN_00794	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IFMEFEAN_00796	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IFMEFEAN_00797	2.29e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IFMEFEAN_00798	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IFMEFEAN_00799	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IFMEFEAN_00800	6.48e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IFMEFEAN_00801	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IFMEFEAN_00802	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IFMEFEAN_00803	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IFMEFEAN_00804	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IFMEFEAN_00805	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IFMEFEAN_00806	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IFMEFEAN_00807	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IFMEFEAN_00808	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFMEFEAN_00809	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IFMEFEAN_00810	5.36e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFMEFEAN_00811	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IFMEFEAN_00812	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IFMEFEAN_00813	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IFMEFEAN_00814	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IFMEFEAN_00815	2.92e-113	ywmA	-	-	-	-	-	-	-
IFMEFEAN_00816	4.54e-45	ywzB	-	-	S	-	-	-	membrane
IFMEFEAN_00817	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
IFMEFEAN_00818	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFMEFEAN_00819	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IFMEFEAN_00820	5.21e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IFMEFEAN_00821	3.4e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IFMEFEAN_00823	9.06e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IFMEFEAN_00824	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IFMEFEAN_00825	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_00826	8.55e-110	ywmF	-	-	S	-	-	-	Peptidase M50
IFMEFEAN_00827	2.15e-19	csbD	-	-	K	-	-	-	CsbD-like
IFMEFEAN_00828	0.000282	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IFMEFEAN_00829	6.75e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IFMEFEAN_00830	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IFMEFEAN_00831	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IFMEFEAN_00832	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00833	6.73e-19	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IFMEFEAN_00834	1.42e-112	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IFMEFEAN_00835	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IFMEFEAN_00836	1.28e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IFMEFEAN_00837	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFMEFEAN_00838	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IFMEFEAN_00839	6.7e-234	-	-	-	M	-	-	-	NeuB family
IFMEFEAN_00840	5.63e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IFMEFEAN_00841	2.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IFMEFEAN_00842	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IFMEFEAN_00843	9.05e-93	ywnJ	-	-	S	-	-	-	VanZ like family
IFMEFEAN_00844	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IFMEFEAN_00845	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IFMEFEAN_00846	3.76e-287	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IFMEFEAN_00847	7.16e-101	-	-	-	-	-	-	-	-
IFMEFEAN_00848	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
IFMEFEAN_00849	8.92e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IFMEFEAN_00850	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IFMEFEAN_00851	3.25e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
IFMEFEAN_00852	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_00853	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
IFMEFEAN_00854	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IFMEFEAN_00855	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IFMEFEAN_00856	9.37e-168	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IFMEFEAN_00857	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IFMEFEAN_00858	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IFMEFEAN_00859	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IFMEFEAN_00860	7.66e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IFMEFEAN_00861	4.66e-186	ywpD	-	-	T	-	-	-	Histidine kinase
IFMEFEAN_00862	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IFMEFEAN_00863	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
IFMEFEAN_00864	2.79e-40	ywpG	-	-	-	-	-	-	-
IFMEFEAN_00865	4.23e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IFMEFEAN_00866	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IFMEFEAN_00867	3.57e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IFMEFEAN_00868	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IFMEFEAN_00869	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IFMEFEAN_00870	3.6e-25	-	-	-	-	-	-	-	-
IFMEFEAN_00871	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IFMEFEAN_00872	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IFMEFEAN_00873	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IFMEFEAN_00874	6.34e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IFMEFEAN_00875	9.48e-193	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IFMEFEAN_00877	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IFMEFEAN_00878	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IFMEFEAN_00879	2.5e-26	-	-	-	-	-	-	-	-
IFMEFEAN_00880	1.3e-23	-	-	-	-	-	-	-	-
IFMEFEAN_00881	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IFMEFEAN_00882	9.77e-48	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
IFMEFEAN_00884	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IFMEFEAN_00885	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_00886	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
IFMEFEAN_00888	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IFMEFEAN_00889	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IFMEFEAN_00890	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IFMEFEAN_00891	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IFMEFEAN_00892	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
IFMEFEAN_00893	5.08e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IFMEFEAN_00894	1e-17	-	-	-	-	-	-	-	-
IFMEFEAN_00895	8.48e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IFMEFEAN_00896	3.02e-44	cotB	-	-	-	ko:K06325	-	ko00000	-
IFMEFEAN_00897	1.06e-162	ywrJ	-	-	-	-	-	-	-
IFMEFEAN_00898	8.01e-263	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IFMEFEAN_00899	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
IFMEFEAN_00900	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IFMEFEAN_00901	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IFMEFEAN_00902	1.24e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IFMEFEAN_00903	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
IFMEFEAN_00904	1.14e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IFMEFEAN_00905	2.59e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IFMEFEAN_00906	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMEFEAN_00907	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IFMEFEAN_00908	3.12e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IFMEFEAN_00909	8.06e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IFMEFEAN_00910	5.85e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IFMEFEAN_00913	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IFMEFEAN_00914	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IFMEFEAN_00915	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00916	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IFMEFEAN_00917	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IFMEFEAN_00918	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_00924	9.88e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IFMEFEAN_00925	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
IFMEFEAN_00926	1.64e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IFMEFEAN_00927	3.14e-193	ybbH	-	-	K	-	-	-	transcriptional
IFMEFEAN_00928	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_00929	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IFMEFEAN_00930	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IFMEFEAN_00931	8.03e-21	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00932	6.63e-270	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_00933	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IFMEFEAN_00934	2.54e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IFMEFEAN_00935	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00936	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_00937	7.76e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IFMEFEAN_00938	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
IFMEFEAN_00940	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IFMEFEAN_00943	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IFMEFEAN_00944	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IFMEFEAN_00945	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IFMEFEAN_00946	2e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IFMEFEAN_00947	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IFMEFEAN_00948	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IFMEFEAN_00949	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IFMEFEAN_00950	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IFMEFEAN_00951	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IFMEFEAN_00952	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IFMEFEAN_00953	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IFMEFEAN_00954	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMEFEAN_00955	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IFMEFEAN_00956	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IFMEFEAN_00957	1.91e-182	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_00958	2.71e-61	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IFMEFEAN_00959	6.71e-28	-	-	-	K	-	-	-	transcriptional
IFMEFEAN_00960	1.5e-26	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_00961	1.68e-48	-	-	-	-	-	-	-	-
IFMEFEAN_00962	1.22e-48	-	-	-	S	-	-	-	DNA binding
IFMEFEAN_00963	3.14e-110	-	-	-	-	-	-	-	-
IFMEFEAN_00968	8.41e-125	-	-	-	-	-	-	-	-
IFMEFEAN_00969	1.8e-87	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
IFMEFEAN_00971	4.69e-96	yqaL	-	-	L	-	-	-	DnaD domain protein
IFMEFEAN_00972	6.06e-102	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IFMEFEAN_00974	2.02e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IFMEFEAN_00975	1.78e-34	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IFMEFEAN_00978	1.19e-37	-	-	-	-	-	-	-	-
IFMEFEAN_00979	6e-147	-	-	-	-	-	-	-	-
IFMEFEAN_00981	1.84e-105	-	-	-	L	-	-	-	Transposase
IFMEFEAN_00982	7.11e-39	-	-	-	-	-	-	-	-
IFMEFEAN_00984	1.19e-66	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IFMEFEAN_00985	5.19e-102	-	-	-	L	-	-	-	phage terminase small subunit
IFMEFEAN_00986	0.0	-	-	-	S	-	-	-	Terminase
IFMEFEAN_00988	2.64e-303	-	-	-	S	-	-	-	Phage portal protein
IFMEFEAN_00989	6.14e-151	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
IFMEFEAN_00990	1.06e-266	-	-	-	S	-	-	-	capsid protein
IFMEFEAN_00991	1.89e-34	-	-	-	-	-	-	-	-
IFMEFEAN_00992	1.4e-50	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IFMEFEAN_00993	5.23e-52	-	-	-	S	-	-	-	Phage head-tail joining protein
IFMEFEAN_00994	8.4e-67	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IFMEFEAN_00996	1.67e-101	-	-	-	N	-	-	-	Phage major tail protein phi13
IFMEFEAN_00997	1.77e-05	-	-	-	-	-	-	-	-
IFMEFEAN_00999	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
IFMEFEAN_01000	1.19e-135	-	-	-	S	-	-	-	Phage tail protein
IFMEFEAN_01001	1.92e-275	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IFMEFEAN_01002	7.5e-92	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IFMEFEAN_01003	1.49e-240	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IFMEFEAN_01004	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IFMEFEAN_01005	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IFMEFEAN_01006	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IFMEFEAN_01007	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01008	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IFMEFEAN_01010	7.43e-160	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IFMEFEAN_01011	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IFMEFEAN_01012	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IFMEFEAN_01013	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IFMEFEAN_01014	2.45e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IFMEFEAN_01015	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IFMEFEAN_01016	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IFMEFEAN_01017	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFMEFEAN_01018	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IFMEFEAN_01019	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFMEFEAN_01020	2.08e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01021	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IFMEFEAN_01022	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IFMEFEAN_01023	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFMEFEAN_01024	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
IFMEFEAN_01028	1.59e-124	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_01030	5.1e-36	-	-	-	-	-	-	-	-
IFMEFEAN_01031	3.39e-98	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IFMEFEAN_01032	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IFMEFEAN_01034	2.44e-127	-	-	-	L	-	-	-	endonuclease activity
IFMEFEAN_01035	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
IFMEFEAN_01036	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IFMEFEAN_01038	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IFMEFEAN_01040	7.28e-132	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01041	4.59e-101	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
IFMEFEAN_01042	1.13e-193	yesF	-	-	GM	-	-	-	NAD(P)H-binding
IFMEFEAN_01043	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IFMEFEAN_01044	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IFMEFEAN_01045	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IFMEFEAN_01046	1.19e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IFMEFEAN_01047	2.56e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
IFMEFEAN_01048	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_01049	7.1e-163	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IFMEFEAN_01050	1.32e-69	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IFMEFEAN_01051	3.95e-184	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMEFEAN_01052	5.28e-123	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMEFEAN_01053	6.98e-77	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMEFEAN_01054	3.57e-120	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMEFEAN_01055	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMEFEAN_01056	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IFMEFEAN_01057	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01058	5.05e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMEFEAN_01059	1.07e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
IFMEFEAN_01060	4.69e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IFMEFEAN_01061	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IFMEFEAN_01062	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IFMEFEAN_01063	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMEFEAN_01064	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IFMEFEAN_01065	2.25e-127	yetA	-	-	-	-	-	-	-
IFMEFEAN_01066	0.0	yetA	-	-	-	-	-	-	-
IFMEFEAN_01067	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IFMEFEAN_01068	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IFMEFEAN_01069	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMEFEAN_01070	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IFMEFEAN_01071	3.66e-157	yetF	-	-	S	-	-	-	membrane
IFMEFEAN_01072	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IFMEFEAN_01073	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_01074	3.28e-44	-	-	-	-	-	-	-	-
IFMEFEAN_01075	1.52e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IFMEFEAN_01076	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IFMEFEAN_01077	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IFMEFEAN_01078	1.3e-38	yetM	-	-	CH	-	-	-	FAD binding domain
IFMEFEAN_01079	5.94e-131	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IFMEFEAN_01080	1.94e-248	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IFMEFEAN_01081	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IFMEFEAN_01082	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IFMEFEAN_01083	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IFMEFEAN_01084	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IFMEFEAN_01085	2.69e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IFMEFEAN_01086	6.7e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IFMEFEAN_01087	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IFMEFEAN_01088	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_01089	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IFMEFEAN_01090	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IFMEFEAN_01091	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IFMEFEAN_01092	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
IFMEFEAN_01093	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IFMEFEAN_01094	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IFMEFEAN_01095	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IFMEFEAN_01096	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IFMEFEAN_01097	2.1e-39	-	-	-	-	-	-	-	-
IFMEFEAN_01098	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IFMEFEAN_01099	5.42e-95	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01100	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
IFMEFEAN_01101	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
IFMEFEAN_01103	5.02e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IFMEFEAN_01104	1.81e-292	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IFMEFEAN_01105	3.84e-273	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
IFMEFEAN_01106	1.17e-315	-	-	-	L	-	-	-	Peptidase, M16
IFMEFEAN_01108	1.31e-303	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IFMEFEAN_01109	1.57e-96	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IFMEFEAN_01110	1.4e-155	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IFMEFEAN_01111	3.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IFMEFEAN_01113	2.76e-65	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IFMEFEAN_01114	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IFMEFEAN_01115	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IFMEFEAN_01116	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IFMEFEAN_01117	2.1e-64	-	-	-	-	-	-	-	-
IFMEFEAN_01118	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
IFMEFEAN_01119	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
IFMEFEAN_01120	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IFMEFEAN_01121	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01122	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IFMEFEAN_01124	1.54e-306	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IFMEFEAN_01125	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01126	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
IFMEFEAN_01127	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IFMEFEAN_01128	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IFMEFEAN_01129	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IFMEFEAN_01130	5.88e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
IFMEFEAN_01131	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IFMEFEAN_01132	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01133	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IFMEFEAN_01134	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IFMEFEAN_01135	1.95e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IFMEFEAN_01136	3.03e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IFMEFEAN_01137	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IFMEFEAN_01138	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IFMEFEAN_01139	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_01140	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IFMEFEAN_01141	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IFMEFEAN_01142	3.81e-275	ywfA	-	-	EGP	-	-	-	-transporter
IFMEFEAN_01143	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IFMEFEAN_01144	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IFMEFEAN_01145	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IFMEFEAN_01146	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IFMEFEAN_01147	3.7e-101	-	-	-	-	-	-	-	-
IFMEFEAN_01148	1.52e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IFMEFEAN_01149	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IFMEFEAN_01150	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IFMEFEAN_01151	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IFMEFEAN_01152	4.71e-239	spsG	-	-	M	-	-	-	Spore Coat
IFMEFEAN_01153	2.47e-164	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IFMEFEAN_01154	7.93e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IFMEFEAN_01155	2.01e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IFMEFEAN_01156	3.06e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IFMEFEAN_01157	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IFMEFEAN_01158	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
IFMEFEAN_01159	3.7e-106	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IFMEFEAN_01160	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
IFMEFEAN_01161	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
IFMEFEAN_01162	1.26e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IFMEFEAN_01163	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IFMEFEAN_01164	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IFMEFEAN_01165	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IFMEFEAN_01166	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IFMEFEAN_01167	6.19e-39	ywdA	-	-	-	-	-	-	-
IFMEFEAN_01168	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IFMEFEAN_01169	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_01170	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
IFMEFEAN_01171	3.69e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IFMEFEAN_01173	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMEFEAN_01174	2.6e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFMEFEAN_01175	1.9e-177	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IFMEFEAN_01176	2.19e-174	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IFMEFEAN_01177	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IFMEFEAN_01179	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IFMEFEAN_01180	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
IFMEFEAN_01181	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IFMEFEAN_01182	8.79e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IFMEFEAN_01184	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IFMEFEAN_01185	9.03e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
IFMEFEAN_01186	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IFMEFEAN_01187	1.93e-62	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IFMEFEAN_01188	3.15e-136	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IFMEFEAN_01189	2.8e-89	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IFMEFEAN_01190	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IFMEFEAN_01191	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IFMEFEAN_01192	5.25e-113	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IFMEFEAN_01194	8.38e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IFMEFEAN_01196	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IFMEFEAN_01197	1.76e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IFMEFEAN_01198	1.11e-41	-	-	-	-	-	-	-	-
IFMEFEAN_01199	3.54e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IFMEFEAN_01200	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IFMEFEAN_01201	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IFMEFEAN_01202	7.8e-49	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IFMEFEAN_01203	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IFMEFEAN_01204	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_01205	1.07e-08	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_01206	1.15e-204	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_01207	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IFMEFEAN_01208	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IFMEFEAN_01209	1.14e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
IFMEFEAN_01210	8.34e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IFMEFEAN_01212	1.14e-124	-	-	-	L	-	-	-	Integrase
IFMEFEAN_01213	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IFMEFEAN_01214	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IFMEFEAN_01215	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01216	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IFMEFEAN_01217	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IFMEFEAN_01218	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IFMEFEAN_01219	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01220	2.05e-173	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IFMEFEAN_01221	3.43e-100	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMEFEAN_01222	1.07e-54	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMEFEAN_01223	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IFMEFEAN_01224	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_01225	8.07e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IFMEFEAN_01226	7.05e-172	yoxB	-	-	-	-	-	-	-
IFMEFEAN_01227	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IFMEFEAN_01228	6.24e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_01229	2.92e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_01230	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IFMEFEAN_01231	8.15e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IFMEFEAN_01232	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IFMEFEAN_01233	2.23e-112	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IFMEFEAN_01234	7.71e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01235	0.0	-	-	-	I	-	-	-	PLD-like domain
IFMEFEAN_01236	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01237	1.38e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01238	9.73e-194	-	-	-	S	-	-	-	membrane
IFMEFEAN_01239	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
IFMEFEAN_01240	4.34e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IFMEFEAN_01241	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IFMEFEAN_01242	5.84e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IFMEFEAN_01243	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
IFMEFEAN_01245	7.51e-205	-	-	-	P	-	-	-	Catalase
IFMEFEAN_01246	2.56e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IFMEFEAN_01247	2.28e-13	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
IFMEFEAN_01248	5.92e-194	-	-	-	EG	-	-	-	Spore germination protein
IFMEFEAN_01249	5.09e-42	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_01250	2.2e-100	-	-	-	-	-	-	-	-
IFMEFEAN_01251	5.32e-60	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
IFMEFEAN_01252	1.88e-19	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
IFMEFEAN_01253	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IFMEFEAN_01254	3.56e-169	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
IFMEFEAN_01255	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
IFMEFEAN_01256	1.79e-66	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IFMEFEAN_01257	2.87e-119	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IFMEFEAN_01258	1.27e-105	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
IFMEFEAN_01260	3.1e-291	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IFMEFEAN_01263	2.01e-108	-	-	-	-	-	-	-	-
IFMEFEAN_01264	5.78e-215	yoaR	-	-	V	-	-	-	vancomycin resistance protein
IFMEFEAN_01265	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IFMEFEAN_01266	7e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01267	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
IFMEFEAN_01268	1.35e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
IFMEFEAN_01269	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_01270	1.89e-100	yoaW	-	-	-	-	-	-	-
IFMEFEAN_01271	4.88e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
IFMEFEAN_01272	8.51e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IFMEFEAN_01275	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
IFMEFEAN_01276	2.62e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
IFMEFEAN_01277	2.11e-49	-	-	-	S	-	-	-	TM2 domain
IFMEFEAN_01278	1.73e-70	-	-	-	K	-	-	-	Helix-turn-helix
IFMEFEAN_01281	1.45e-38	-	-	-	-	-	-	-	-
IFMEFEAN_01283	8.32e-151	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IFMEFEAN_01284	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IFMEFEAN_01285	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_01286	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IFMEFEAN_01287	1.05e-22	-	-	-	-	-	-	-	-
IFMEFEAN_01288	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IFMEFEAN_01289	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
IFMEFEAN_01290	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_01291	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01292	1.42e-211	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IFMEFEAN_01293	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_01294	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IFMEFEAN_01295	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01296	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IFMEFEAN_01297	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IFMEFEAN_01298	6.01e-99	ykuL	-	-	S	-	-	-	CBS domain
IFMEFEAN_01299	7.61e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01300	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
IFMEFEAN_01301	1.74e-222	ykuO	-	-	-	-	-	-	-
IFMEFEAN_01302	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IFMEFEAN_01303	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IFMEFEAN_01304	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IFMEFEAN_01305	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IFMEFEAN_01306	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IFMEFEAN_01307	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
IFMEFEAN_01308	4.23e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
IFMEFEAN_01309	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
IFMEFEAN_01310	1.76e-10	-	-	-	-	-	-	-	-
IFMEFEAN_01311	1.04e-21	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
IFMEFEAN_01312	1.81e-114	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
IFMEFEAN_01315	2.6e-09	-	-	-	T	ko:K21405	-	ko00000,ko03000	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IFMEFEAN_01316	9.99e-59	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_01319	5.28e-79	-	-	-	-	-	-	-	-
IFMEFEAN_01320	4.26e-43	-	-	-	S	-	-	-	Phage integrase family
IFMEFEAN_01321	2.09e-81	-	-	-	S	-	-	-	Phage integrase family
IFMEFEAN_01323	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IFMEFEAN_01324	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IFMEFEAN_01325	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IFMEFEAN_01326	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IFMEFEAN_01327	2.84e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
IFMEFEAN_01328	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
IFMEFEAN_01329	6.83e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IFMEFEAN_01330	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IFMEFEAN_01331	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
IFMEFEAN_01332	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_01333	3.07e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IFMEFEAN_01334	7.93e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IFMEFEAN_01335	1.27e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IFMEFEAN_01336	2.46e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IFMEFEAN_01337	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IFMEFEAN_01338	1.13e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IFMEFEAN_01339	1.23e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IFMEFEAN_01340	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IFMEFEAN_01341	3.23e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IFMEFEAN_01342	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IFMEFEAN_01343	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IFMEFEAN_01344	1.2e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
IFMEFEAN_01345	2.66e-155	yvbI	-	-	M	-	-	-	Membrane
IFMEFEAN_01346	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IFMEFEAN_01347	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
IFMEFEAN_01348	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFMEFEAN_01349	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IFMEFEAN_01350	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IFMEFEAN_01351	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IFMEFEAN_01352	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IFMEFEAN_01353	4.01e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IFMEFEAN_01354	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_01355	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IFMEFEAN_01356	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFMEFEAN_01357	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01358	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_01359	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_01360	2.7e-187	-	-	-	S	-	-	-	Glycosyl hydrolase
IFMEFEAN_01361	6.88e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IFMEFEAN_01362	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IFMEFEAN_01363	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IFMEFEAN_01364	3.88e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IFMEFEAN_01365	4.23e-42	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IFMEFEAN_01366	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_01367	1.09e-251	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_01368	8.31e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IFMEFEAN_01369	1.1e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IFMEFEAN_01370	8.47e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
IFMEFEAN_01371	1.89e-259	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
IFMEFEAN_01372	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IFMEFEAN_01373	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
IFMEFEAN_01374	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IFMEFEAN_01375	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IFMEFEAN_01376	3.8e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IFMEFEAN_01377	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01378	5.87e-147	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IFMEFEAN_01379	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IFMEFEAN_01380	7.05e-306	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IFMEFEAN_01381	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
IFMEFEAN_01382	3.07e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IFMEFEAN_01383	1.06e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IFMEFEAN_01384	3.33e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IFMEFEAN_01385	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IFMEFEAN_01386	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_01387	5.49e-240	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IFMEFEAN_01388	1.83e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IFMEFEAN_01389	9.61e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IFMEFEAN_01390	7.25e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IFMEFEAN_01391	1.28e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IFMEFEAN_01392	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IFMEFEAN_01393	5.25e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IFMEFEAN_01394	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IFMEFEAN_01395	2.28e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IFMEFEAN_01396	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IFMEFEAN_01397	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IFMEFEAN_01398	1.85e-72	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IFMEFEAN_01399	6.68e-19	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IFMEFEAN_01400	2.17e-224	pbpE	-	-	V	-	-	-	Beta-lactamase
IFMEFEAN_01401	3.77e-79	pbpE	-	-	V	-	-	-	Beta-lactamase
IFMEFEAN_01402	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IFMEFEAN_01403	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IFMEFEAN_01404	0.0	ybeC	-	-	E	-	-	-	amino acid
IFMEFEAN_01405	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01406	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IFMEFEAN_01407	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IFMEFEAN_01408	4.53e-95	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
IFMEFEAN_01410	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IFMEFEAN_01411	4.39e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IFMEFEAN_01412	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IFMEFEAN_01413	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
IFMEFEAN_01414	1.02e-199	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IFMEFEAN_01415	2.29e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IFMEFEAN_01416	2.88e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IFMEFEAN_01417	3.44e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IFMEFEAN_01418	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
IFMEFEAN_01419	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01420	3.11e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IFMEFEAN_01421	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IFMEFEAN_01422	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IFMEFEAN_01423	5.3e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IFMEFEAN_01424	5.45e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFMEFEAN_01425	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IFMEFEAN_01426	3.67e-180	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_01427	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IFMEFEAN_01428	3.69e-169	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_01429	7.42e-29	-	-	-	-	-	-	-	-
IFMEFEAN_01430	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IFMEFEAN_01431	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IFMEFEAN_01432	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IFMEFEAN_01433	5.52e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IFMEFEAN_01434	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IFMEFEAN_01435	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IFMEFEAN_01436	3.89e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IFMEFEAN_01437	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IFMEFEAN_01438	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IFMEFEAN_01439	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IFMEFEAN_01441	0.0	-	-	-	-	-	-	-	-
IFMEFEAN_01442	3.7e-111	-	-	-	-	-	-	-	-
IFMEFEAN_01443	2.93e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IFMEFEAN_01444	3.97e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IFMEFEAN_01445	4.61e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IFMEFEAN_01446	3.29e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IFMEFEAN_01447	2.02e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IFMEFEAN_01448	1.81e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IFMEFEAN_01449	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IFMEFEAN_01450	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IFMEFEAN_01451	4.31e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IFMEFEAN_01452	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
IFMEFEAN_01453	5.85e-164	-	-	-	-	-	-	-	-
IFMEFEAN_01454	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IFMEFEAN_01455	1.51e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IFMEFEAN_01456	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IFMEFEAN_01457	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IFMEFEAN_01458	5.87e-74	eag	-	-	-	-	-	-	-
IFMEFEAN_01460	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IFMEFEAN_01461	1.02e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IFMEFEAN_01462	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IFMEFEAN_01463	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IFMEFEAN_01464	2.79e-294	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IFMEFEAN_01465	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IFMEFEAN_01466	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IFMEFEAN_01467	7.07e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IFMEFEAN_01468	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IFMEFEAN_01470	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IFMEFEAN_01471	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_01472	4.75e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IFMEFEAN_01473	4.83e-30	ykzE	-	-	-	-	-	-	-
IFMEFEAN_01475	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IFMEFEAN_01476	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IFMEFEAN_01477	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IFMEFEAN_01478	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IFMEFEAN_01479	3.83e-204	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IFMEFEAN_01480	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_01481	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IFMEFEAN_01482	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
IFMEFEAN_01483	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IFMEFEAN_01484	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IFMEFEAN_01485	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IFMEFEAN_01486	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IFMEFEAN_01487	0.0	ykoS	-	-	-	-	-	-	-
IFMEFEAN_01488	1.2e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IFMEFEAN_01489	2.12e-121	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IFMEFEAN_01490	6.33e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IFMEFEAN_01491	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IFMEFEAN_01492	3.04e-36	ykoL	-	-	-	-	-	-	-
IFMEFEAN_01493	1.63e-25	-	-	-	-	-	-	-	-
IFMEFEAN_01494	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
IFMEFEAN_01495	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IFMEFEAN_01497	1.45e-08	-	-	-	-	-	-	-	-
IFMEFEAN_01498	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IFMEFEAN_01499	7.88e-145	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IFMEFEAN_01500	6.05e-307	ykoH	-	-	T	-	-	-	Histidine kinase
IFMEFEAN_01501	1.68e-156	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_01502	4.05e-141	ykoF	-	-	S	-	-	-	YKOF-related Family
IFMEFEAN_01503	3.99e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IFMEFEAN_01504	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_01505	5.18e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IFMEFEAN_01506	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IFMEFEAN_01507	6.07e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMEFEAN_01508	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IFMEFEAN_01509	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
IFMEFEAN_01510	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IFMEFEAN_01511	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IFMEFEAN_01512	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IFMEFEAN_01513	4.59e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IFMEFEAN_01514	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IFMEFEAN_01515	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IFMEFEAN_01516	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IFMEFEAN_01517	2.99e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IFMEFEAN_01518	6.97e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IFMEFEAN_01519	2.51e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
IFMEFEAN_01520	1.32e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01521	9.93e-15	-	-	-	-	-	-	-	-
IFMEFEAN_01522	4.21e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IFMEFEAN_01523	5.42e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IFMEFEAN_01524	9.79e-102	ykgA	-	-	E	-	-	-	Amidinotransferase
IFMEFEAN_01525	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IFMEFEAN_01526	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_01527	4.03e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IFMEFEAN_01528	3.21e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IFMEFEAN_01529	5.33e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IFMEFEAN_01531	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMEFEAN_01532	7.78e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_01533	8.28e-222	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_01534	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_01535	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IFMEFEAN_01536	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
IFMEFEAN_01537	2.73e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IFMEFEAN_01539	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IFMEFEAN_01540	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IFMEFEAN_01541	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IFMEFEAN_01542	1.81e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IFMEFEAN_01543	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IFMEFEAN_01544	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IFMEFEAN_01545	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IFMEFEAN_01546	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IFMEFEAN_01547	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_01548	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
IFMEFEAN_01549	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IFMEFEAN_01550	9.79e-195	xepA	-	-	-	-	-	-	-
IFMEFEAN_01551	6.35e-31	xkdX	-	-	-	-	-	-	-
IFMEFEAN_01552	2.7e-68	xkdW	-	-	S	-	-	-	XkdW protein
IFMEFEAN_01553	0.0	-	-	-	-	-	-	-	-
IFMEFEAN_01554	4.43e-56	-	-	-	-	-	-	-	-
IFMEFEAN_01555	3.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IFMEFEAN_01556	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IFMEFEAN_01557	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IFMEFEAN_01558	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IFMEFEAN_01559	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
IFMEFEAN_01560	1.73e-151	xkdP	-	-	S	-	-	-	Lysin motif
IFMEFEAN_01561	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IFMEFEAN_01562	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IFMEFEAN_01563	2.45e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
IFMEFEAN_01564	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IFMEFEAN_01565	2.87e-101	xkdJ	-	-	-	-	-	-	-
IFMEFEAN_01566	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IFMEFEAN_01567	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IFMEFEAN_01568	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IFMEFEAN_01569	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
IFMEFEAN_01570	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IFMEFEAN_01571	0.0	yqbA	-	-	S	-	-	-	portal protein
IFMEFEAN_01572	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IFMEFEAN_01573	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IFMEFEAN_01574	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IFMEFEAN_01579	8.72e-152	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IFMEFEAN_01580	2.52e-201	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
IFMEFEAN_01582	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_01583	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IFMEFEAN_01584	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
IFMEFEAN_01585	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
IFMEFEAN_01586	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
IFMEFEAN_01587	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IFMEFEAN_01588	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
IFMEFEAN_01590	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_01591	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IFMEFEAN_01592	8.23e-228	ykvI	-	-	S	-	-	-	membrane
IFMEFEAN_01593	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IFMEFEAN_01594	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IFMEFEAN_01595	2.41e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IFMEFEAN_01596	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IFMEFEAN_01597	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IFMEFEAN_01598	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01599	2.6e-39	-	-	-	-	-	-	-	-
IFMEFEAN_01600	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IFMEFEAN_01601	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_01602	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
IFMEFEAN_01603	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IFMEFEAN_01604	3.99e-09	-	-	-	-	-	-	-	-
IFMEFEAN_01605	3.19e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IFMEFEAN_01606	2.21e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01607	1.97e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IFMEFEAN_01608	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_01609	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IFMEFEAN_01610	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IFMEFEAN_01611	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_01612	5.86e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IFMEFEAN_01613	6.21e-162	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_01614	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_01615	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IFMEFEAN_01617	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IFMEFEAN_01618	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IFMEFEAN_01619	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01620	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IFMEFEAN_01621	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IFMEFEAN_01622	2.99e-220	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IFMEFEAN_01623	9.76e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IFMEFEAN_01624	6.79e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IFMEFEAN_01625	2.57e-252	yutH	-	-	S	-	-	-	Spore coat protein
IFMEFEAN_01626	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IFMEFEAN_01627	2.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IFMEFEAN_01628	1.61e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IFMEFEAN_01629	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_01630	1.34e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IFMEFEAN_01631	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IFMEFEAN_01632	1.08e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IFMEFEAN_01633	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IFMEFEAN_01634	5.67e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
IFMEFEAN_01635	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IFMEFEAN_01636	7.59e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IFMEFEAN_01637	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IFMEFEAN_01638	1.07e-79	yunG	-	-	-	-	-	-	-
IFMEFEAN_01639	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IFMEFEAN_01640	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IFMEFEAN_01641	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
IFMEFEAN_01642	4.37e-273	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IFMEFEAN_01643	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IFMEFEAN_01644	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IFMEFEAN_01646	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IFMEFEAN_01647	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IFMEFEAN_01648	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IFMEFEAN_01649	2.47e-187	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IFMEFEAN_01650	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IFMEFEAN_01651	7.18e-234	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IFMEFEAN_01652	9.52e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IFMEFEAN_01653	4.82e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IFMEFEAN_01654	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
IFMEFEAN_01655	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_01656	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IFMEFEAN_01657	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IFMEFEAN_01658	4.53e-107	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IFMEFEAN_01659	1.29e-89	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IFMEFEAN_01660	2.05e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IFMEFEAN_01661	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IFMEFEAN_01662	9.11e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IFMEFEAN_01663	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IFMEFEAN_01664	2.63e-264	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IFMEFEAN_01666	3.35e-56	-	-	-	-	-	-	-	-
IFMEFEAN_01667	5.95e-306	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_01668	1.39e-37	-	-	-	L	-	-	-	DnaD domain protein
IFMEFEAN_01670	0.000533	-	-	-	K	ko:K07075,ko:K15773	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
IFMEFEAN_01671	1.47e-67	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IFMEFEAN_01682	2.17e-10	-	-	-	-	-	-	-	-
IFMEFEAN_01683	4.66e-68	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IFMEFEAN_01684	1.7e-177	-	-	-	M	-	-	-	Psort location Cellwall, score
IFMEFEAN_01691	4.77e-16	-	-	-	S	-	-	-	YolD-like protein
IFMEFEAN_01693	1.48e-34	-	-	-	-	-	-	-	-
IFMEFEAN_01694	2.37e-47	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
IFMEFEAN_01696	8.48e-171	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_01700	4.71e-55	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IFMEFEAN_01701	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IFMEFEAN_01702	3.75e-39	-	-	-	-	-	-	-	-
IFMEFEAN_01704	5e-152	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01705	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IFMEFEAN_01706	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IFMEFEAN_01707	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IFMEFEAN_01708	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IFMEFEAN_01709	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMEFEAN_01710	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
IFMEFEAN_01711	8.04e-111	yycN	-	-	K	-	-	-	Acetyltransferase
IFMEFEAN_01712	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IFMEFEAN_01713	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_01714	6.94e-117	-	-	-	S	-	-	-	DinB family
IFMEFEAN_01715	1.19e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IFMEFEAN_01716	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IFMEFEAN_01717	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
IFMEFEAN_01718	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IFMEFEAN_01719	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IFMEFEAN_01720	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IFMEFEAN_01721	1.24e-156	ydhC	-	-	K	-	-	-	FCD
IFMEFEAN_01722	5.08e-300	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IFMEFEAN_01723	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IFMEFEAN_01725	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IFMEFEAN_01726	1.46e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IFMEFEAN_01727	6.33e-103	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
IFMEFEAN_01728	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IFMEFEAN_01729	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_01730	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IFMEFEAN_01731	5.62e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IFMEFEAN_01732	1.07e-283	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IFMEFEAN_01733	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IFMEFEAN_01734	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IFMEFEAN_01735	6.3e-111	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_01736	1.15e-314	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IFMEFEAN_01737	6.6e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IFMEFEAN_01738	5.85e-165	yebC	-	-	M	-	-	-	Membrane
IFMEFEAN_01739	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IFMEFEAN_01740	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IFMEFEAN_01741	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
IFMEFEAN_01742	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IFMEFEAN_01743	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IFMEFEAN_01745	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IFMEFEAN_01746	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IFMEFEAN_01747	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IFMEFEAN_01748	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IFMEFEAN_01749	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IFMEFEAN_01750	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IFMEFEAN_01751	1.3e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IFMEFEAN_01752	1.05e-250	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IFMEFEAN_01753	6.06e-61	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IFMEFEAN_01754	7.75e-258	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IFMEFEAN_01755	8.52e-260	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_01756	3.53e-178	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01757	1.99e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IFMEFEAN_01758	3.19e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IFMEFEAN_01759	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IFMEFEAN_01760	8.03e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IFMEFEAN_01761	5.77e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
IFMEFEAN_01762	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IFMEFEAN_01763	1.82e-275	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IFMEFEAN_01764	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IFMEFEAN_01765	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
IFMEFEAN_01766	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IFMEFEAN_01767	6.46e-210	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IFMEFEAN_01768	4.64e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IFMEFEAN_01769	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IFMEFEAN_01770	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IFMEFEAN_01771	4.13e-78	yhjD	-	-	-	-	-	-	-
IFMEFEAN_01772	2.82e-140	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IFMEFEAN_01773	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMEFEAN_01774	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IFMEFEAN_01775	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IFMEFEAN_01778	3.5e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IFMEFEAN_01779	9.38e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IFMEFEAN_01780	8.81e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
IFMEFEAN_01781	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IFMEFEAN_01782	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01783	5.04e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IFMEFEAN_01784	1.36e-267	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IFMEFEAN_01785	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
IFMEFEAN_01786	6.29e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
IFMEFEAN_01787	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IFMEFEAN_01788	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IFMEFEAN_01789	3.84e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IFMEFEAN_01790	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IFMEFEAN_01791	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IFMEFEAN_01792	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IFMEFEAN_01793	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IFMEFEAN_01794	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IFMEFEAN_01795	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IFMEFEAN_01796	1.02e-46	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IFMEFEAN_01797	7.41e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IFMEFEAN_01798	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IFMEFEAN_01799	1.88e-222	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IFMEFEAN_01800	3.11e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IFMEFEAN_01801	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
IFMEFEAN_01802	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMEFEAN_01803	7.92e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IFMEFEAN_01804	5.85e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IFMEFEAN_01805	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IFMEFEAN_01806	3.23e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IFMEFEAN_01807	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IFMEFEAN_01808	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IFMEFEAN_01809	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IFMEFEAN_01810	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IFMEFEAN_01811	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IFMEFEAN_01812	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IFMEFEAN_01813	1.44e-167	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IFMEFEAN_01814	5.69e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IFMEFEAN_01815	4.1e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IFMEFEAN_01816	2.78e-224	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
IFMEFEAN_01817	7.32e-292	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
IFMEFEAN_01819	6.65e-261	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
IFMEFEAN_01820	1.61e-272	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
IFMEFEAN_01821	3.68e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
IFMEFEAN_01822	1.75e-95	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IFMEFEAN_01823	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IFMEFEAN_01824	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IFMEFEAN_01825	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
IFMEFEAN_01826	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IFMEFEAN_01827	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IFMEFEAN_01849	5.89e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
IFMEFEAN_01850	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IFMEFEAN_01851	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IFMEFEAN_01852	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IFMEFEAN_01853	5.55e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IFMEFEAN_01854	4.64e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IFMEFEAN_01856	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IFMEFEAN_01857	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IFMEFEAN_01858	7.55e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IFMEFEAN_01859	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IFMEFEAN_01860	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IFMEFEAN_01861	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFMEFEAN_01862	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IFMEFEAN_01863	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IFMEFEAN_01864	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IFMEFEAN_01865	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IFMEFEAN_01866	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IFMEFEAN_01867	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IFMEFEAN_01869	4.82e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IFMEFEAN_01870	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IFMEFEAN_01871	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IFMEFEAN_01872	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IFMEFEAN_01873	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IFMEFEAN_01874	7.16e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IFMEFEAN_01875	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IFMEFEAN_01876	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
IFMEFEAN_01877	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IFMEFEAN_01878	4.1e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IFMEFEAN_01879	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IFMEFEAN_01880	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
IFMEFEAN_01881	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IFMEFEAN_01882	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
IFMEFEAN_01883	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IFMEFEAN_01884	3.67e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IFMEFEAN_01885	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IFMEFEAN_01886	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IFMEFEAN_01887	1.52e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IFMEFEAN_01888	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IFMEFEAN_01889	7.79e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IFMEFEAN_01890	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IFMEFEAN_01891	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IFMEFEAN_01892	0.0	-	-	-	-	-	-	-	-
IFMEFEAN_01893	1.22e-136	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IFMEFEAN_01895	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
IFMEFEAN_01898	1.46e-33	-	-	-	-	-	-	-	-
IFMEFEAN_01900	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IFMEFEAN_01901	8.17e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
IFMEFEAN_01903	5.45e-13	-	-	-	-	-	-	-	-
IFMEFEAN_01904	7.58e-162	-	-	-	S	-	-	-	capsid protein
IFMEFEAN_01905	1.32e-92	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IFMEFEAN_01906	1.33e-216	-	-	-	S	-	-	-	portal protein
IFMEFEAN_01908	1.19e-179	terL	-	-	S	-	-	-	Terminase
IFMEFEAN_01909	3.93e-73	-	-	-	L	-	-	-	Terminase, small subunit
IFMEFEAN_01915	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IFMEFEAN_01916	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IFMEFEAN_01917	3.49e-145	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
IFMEFEAN_01921	2.98e-53	-	-	-	-	-	-	-	-
IFMEFEAN_01922	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IFMEFEAN_01923	5.9e-171	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IFMEFEAN_01924	9.99e-59	-	-	-	-	-	-	-	-
IFMEFEAN_01925	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_01926	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_01927	4.46e-153	-	-	-	E	-	-	-	amino acid
IFMEFEAN_01935	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IFMEFEAN_01936	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IFMEFEAN_01937	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IFMEFEAN_01938	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_01939	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IFMEFEAN_01940	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IFMEFEAN_01941	1.08e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IFMEFEAN_01942	1e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IFMEFEAN_01943	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IFMEFEAN_01944	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IFMEFEAN_01945	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IFMEFEAN_01946	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IFMEFEAN_01947	2.07e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IFMEFEAN_01948	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IFMEFEAN_01949	1.87e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IFMEFEAN_01950	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IFMEFEAN_01951	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IFMEFEAN_01952	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IFMEFEAN_01953	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IFMEFEAN_01954	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IFMEFEAN_01955	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IFMEFEAN_01956	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
IFMEFEAN_01957	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IFMEFEAN_01959	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
IFMEFEAN_01960	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IFMEFEAN_01961	9.32e-70	ydbL	-	-	-	-	-	-	-
IFMEFEAN_01962	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IFMEFEAN_01963	2.66e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_01964	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
IFMEFEAN_01965	7.33e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IFMEFEAN_01966	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IFMEFEAN_01967	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IFMEFEAN_01968	4.99e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IFMEFEAN_01969	6.41e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IFMEFEAN_01970	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
IFMEFEAN_01971	2.17e-78	ydbB	-	-	G	-	-	-	Cupin domain
IFMEFEAN_01972	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IFMEFEAN_01973	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
IFMEFEAN_01974	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IFMEFEAN_01975	1.67e-42	ydaS	-	-	S	-	-	-	membrane
IFMEFEAN_01976	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IFMEFEAN_01977	6.14e-53	-	-	-	-	-	-	-	-
IFMEFEAN_01979	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
IFMEFEAN_01980	1.84e-34	-	-	-	-	-	-	-	-
IFMEFEAN_01981	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IFMEFEAN_01982	5.12e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IFMEFEAN_01983	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IFMEFEAN_01984	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IFMEFEAN_01985	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IFMEFEAN_01986	2.65e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IFMEFEAN_01987	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
IFMEFEAN_01988	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IFMEFEAN_01989	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IFMEFEAN_01990	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_01991	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
IFMEFEAN_01992	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IFMEFEAN_01993	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IFMEFEAN_01994	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
IFMEFEAN_01995	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IFMEFEAN_01996	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
IFMEFEAN_01998	5.94e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IFMEFEAN_01999	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02000	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IFMEFEAN_02001	9.77e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IFMEFEAN_02002	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IFMEFEAN_02003	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IFMEFEAN_02004	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IFMEFEAN_02005	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IFMEFEAN_02007	6.48e-288	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IFMEFEAN_02008	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IFMEFEAN_02009	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
IFMEFEAN_02010	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
IFMEFEAN_02011	2.76e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IFMEFEAN_02012	1.74e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
IFMEFEAN_02013	3.24e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IFMEFEAN_02014	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
IFMEFEAN_02015	3.9e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IFMEFEAN_02016	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IFMEFEAN_02017	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IFMEFEAN_02018	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IFMEFEAN_02020	4.22e-164	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IFMEFEAN_02021	2.5e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_02022	4.9e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
IFMEFEAN_02023	2.2e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IFMEFEAN_02024	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_02025	1.19e-191	-	-	-	S	-	-	-	Alpha beta hydrolase
IFMEFEAN_02026	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
IFMEFEAN_02027	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
IFMEFEAN_02028	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
IFMEFEAN_02029	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
IFMEFEAN_02030	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
IFMEFEAN_02031	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IFMEFEAN_02032	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
IFMEFEAN_02033	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IFMEFEAN_02034	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IFMEFEAN_02035	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
IFMEFEAN_02036	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IFMEFEAN_02037	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IFMEFEAN_02038	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IFMEFEAN_02039	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IFMEFEAN_02040	1.75e-167	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IFMEFEAN_02041	4.41e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
IFMEFEAN_02042	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IFMEFEAN_02043	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
IFMEFEAN_02044	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_02045	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
IFMEFEAN_02046	3.41e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
IFMEFEAN_02047	5.77e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_02048	3.51e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IFMEFEAN_02049	2.18e-84	oatA	-	-	I	-	-	-	Acyltransferase family
IFMEFEAN_02050	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IFMEFEAN_02051	2.58e-58	yrhK	-	-	S	-	-	-	YrhK-like protein
IFMEFEAN_02052	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IFMEFEAN_02053	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IFMEFEAN_02054	4.3e-124	yrhH	-	-	Q	-	-	-	methyltransferase
IFMEFEAN_02055	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IFMEFEAN_02057	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IFMEFEAN_02059	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IFMEFEAN_02060	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IFMEFEAN_02061	2.46e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IFMEFEAN_02062	5.71e-48	yrhC	-	-	S	-	-	-	YrhC-like protein
IFMEFEAN_02063	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IFMEFEAN_02064	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IFMEFEAN_02065	3.26e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IFMEFEAN_02066	9.86e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IFMEFEAN_02067	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IFMEFEAN_02068	2.02e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IFMEFEAN_02069	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IFMEFEAN_02070	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFMEFEAN_02071	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IFMEFEAN_02072	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IFMEFEAN_02073	2.57e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IFMEFEAN_02074	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IFMEFEAN_02075	6.17e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IFMEFEAN_02076	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IFMEFEAN_02077	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IFMEFEAN_02078	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IFMEFEAN_02079	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IFMEFEAN_02080	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
IFMEFEAN_02081	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IFMEFEAN_02082	3.93e-182	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IFMEFEAN_02083	1.54e-137	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_02084	1.54e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_02085	5.04e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
IFMEFEAN_02086	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IFMEFEAN_02087	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IFMEFEAN_02088	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IFMEFEAN_02089	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_02090	1.45e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IFMEFEAN_02091	3.72e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_02092	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IFMEFEAN_02093	2.89e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IFMEFEAN_02094	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_02095	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_02096	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IFMEFEAN_02097	2.05e-256	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IFMEFEAN_02098	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_02099	1.12e-242	yhdN	-	-	C	-	-	-	Aldo keto reductase
IFMEFEAN_02100	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IFMEFEAN_02101	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IFMEFEAN_02102	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IFMEFEAN_02103	3.35e-92	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IFMEFEAN_02104	1.21e-169	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IFMEFEAN_02105	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IFMEFEAN_02106	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFMEFEAN_02107	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFMEFEAN_02108	9.03e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IFMEFEAN_02109	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IFMEFEAN_02110	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IFMEFEAN_02111	9.4e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IFMEFEAN_02112	9.72e-192	nodB1	-	-	G	-	-	-	deacetylase
IFMEFEAN_02113	2.6e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IFMEFEAN_02114	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IFMEFEAN_02115	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
IFMEFEAN_02116	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IFMEFEAN_02117	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IFMEFEAN_02118	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IFMEFEAN_02119	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IFMEFEAN_02120	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IFMEFEAN_02121	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IFMEFEAN_02122	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IFMEFEAN_02123	1.19e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IFMEFEAN_02124	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IFMEFEAN_02125	2.11e-131	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IFMEFEAN_02126	3.3e-92	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IFMEFEAN_02127	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IFMEFEAN_02128	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IFMEFEAN_02129	4.36e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IFMEFEAN_02130	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IFMEFEAN_02132	1.45e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IFMEFEAN_02133	1.89e-35	-	-	-	S	-	-	-	YhzD-like protein
IFMEFEAN_02134	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_02135	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IFMEFEAN_02136	8.42e-302	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IFMEFEAN_02137	0.0	yhaN	-	-	L	-	-	-	AAA domain
IFMEFEAN_02138	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IFMEFEAN_02139	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IFMEFEAN_02140	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IFMEFEAN_02141	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IFMEFEAN_02142	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IFMEFEAN_02143	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IFMEFEAN_02144	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
IFMEFEAN_02145	1.28e-103	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IFMEFEAN_02146	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IFMEFEAN_02147	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IFMEFEAN_02148	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IFMEFEAN_02149	4.23e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IFMEFEAN_02150	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
IFMEFEAN_02151	1.27e-290	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IFMEFEAN_02152	2.7e-312	yhfA	-	-	C	-	-	-	membrane
IFMEFEAN_02153	1e-44	-	-	-	C	-	-	-	Rubrerythrin
IFMEFEAN_02154	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IFMEFEAN_02155	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IFMEFEAN_02156	1.24e-257	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IFMEFEAN_02157	3.28e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IFMEFEAN_02158	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IFMEFEAN_02159	6.76e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_02160	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IFMEFEAN_02161	1.77e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IFMEFEAN_02162	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IFMEFEAN_02163	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
IFMEFEAN_02164	1.79e-92	-	-	-	S	-	-	-	ASCH
IFMEFEAN_02165	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IFMEFEAN_02166	1.63e-180	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IFMEFEAN_02167	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IFMEFEAN_02168	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
IFMEFEAN_02169	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IFMEFEAN_02172	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFMEFEAN_02173	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFMEFEAN_02174	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
IFMEFEAN_02175	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IFMEFEAN_02176	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IFMEFEAN_02177	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IFMEFEAN_02178	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IFMEFEAN_02179	8.55e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IFMEFEAN_02180	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IFMEFEAN_02181	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IFMEFEAN_02182	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IFMEFEAN_02183	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_02184	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IFMEFEAN_02185	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IFMEFEAN_02186	8.27e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IFMEFEAN_02187	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IFMEFEAN_02188	3.77e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IFMEFEAN_02189	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IFMEFEAN_02190	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IFMEFEAN_02191	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IFMEFEAN_02192	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IFMEFEAN_02193	1.47e-41	yqkK	-	-	-	-	-	-	-
IFMEFEAN_02194	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IFMEFEAN_02195	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IFMEFEAN_02196	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IFMEFEAN_02197	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IFMEFEAN_02198	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02199	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
IFMEFEAN_02200	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IFMEFEAN_02201	6.19e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IFMEFEAN_02202	2.09e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IFMEFEAN_02203	8.04e-27	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
IFMEFEAN_02204	4.61e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IFMEFEAN_02205	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IFMEFEAN_02206	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IFMEFEAN_02207	3.23e-248	yqkA	-	-	K	-	-	-	GrpB protein
IFMEFEAN_02208	1.52e-76	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IFMEFEAN_02209	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IFMEFEAN_02210	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
IFMEFEAN_02211	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFMEFEAN_02213	4.23e-287	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
IFMEFEAN_02215	2.21e-94	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_02216	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IFMEFEAN_02217	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IFMEFEAN_02218	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_02219	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IFMEFEAN_02220	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMEFEAN_02221	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IFMEFEAN_02222	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IFMEFEAN_02223	1.74e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IFMEFEAN_02224	5.07e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IFMEFEAN_02225	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IFMEFEAN_02226	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IFMEFEAN_02227	4.16e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
IFMEFEAN_02228	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IFMEFEAN_02229	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IFMEFEAN_02230	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IFMEFEAN_02231	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IFMEFEAN_02232	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
IFMEFEAN_02233	8.09e-65	yvlA	-	-	-	-	-	-	-
IFMEFEAN_02234	2.25e-45	yvkN	-	-	-	-	-	-	-
IFMEFEAN_02235	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IFMEFEAN_02236	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IFMEFEAN_02237	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IFMEFEAN_02238	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02239	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IFMEFEAN_02240	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02241	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
IFMEFEAN_02242	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IFMEFEAN_02243	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IFMEFEAN_02244	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IFMEFEAN_02245	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IFMEFEAN_02246	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IFMEFEAN_02247	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IFMEFEAN_02248	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IFMEFEAN_02249	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IFMEFEAN_02250	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IFMEFEAN_02251	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IFMEFEAN_02252	1.36e-37	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFMEFEAN_02253	2.02e-48	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFMEFEAN_02254	4.84e-85	-	-	-	S	-	-	-	damaged DNA binding
IFMEFEAN_02255	2.34e-14	-	-	-	S	-	-	-	YolD-like protein
IFMEFEAN_02258	1.06e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_02259	7.01e-129	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
IFMEFEAN_02260	3.18e-101	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IFMEFEAN_02261	1.35e-111	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IFMEFEAN_02262	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IFMEFEAN_02263	2.8e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
IFMEFEAN_02264	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
IFMEFEAN_02265	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IFMEFEAN_02266	5.45e-173	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IFMEFEAN_02267	2.81e-178	-	-	-	J	-	-	-	FR47-like protein
IFMEFEAN_02268	6.23e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02269	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IFMEFEAN_02270	4.8e-111	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IFMEFEAN_02271	1.73e-221	yobV	-	-	K	-	-	-	WYL domain
IFMEFEAN_02272	7.38e-121	yobW	-	-	-	-	-	-	-
IFMEFEAN_02273	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IFMEFEAN_02274	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IFMEFEAN_02275	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IFMEFEAN_02276	2.44e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IFMEFEAN_02277	2.09e-212	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IFMEFEAN_02278	5.28e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IFMEFEAN_02279	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IFMEFEAN_02280	1.31e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IFMEFEAN_02281	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
IFMEFEAN_02282	3.75e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IFMEFEAN_02283	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IFMEFEAN_02284	1.89e-40	-	-	-	-	-	-	-	-
IFMEFEAN_02285	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
IFMEFEAN_02289	5.24e-60	-	-	-	-	-	-	-	-
IFMEFEAN_02290	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
IFMEFEAN_02291	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IFMEFEAN_02293	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IFMEFEAN_02294	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IFMEFEAN_02295	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IFMEFEAN_02296	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
IFMEFEAN_02298	8.28e-87	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
IFMEFEAN_02299	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02300	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IFMEFEAN_02301	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_02302	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IFMEFEAN_02303	7.4e-168	-	-	-	-	-	-	-	-
IFMEFEAN_02304	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IFMEFEAN_02305	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IFMEFEAN_02306	2.3e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_02307	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMEFEAN_02309	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IFMEFEAN_02310	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IFMEFEAN_02311	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IFMEFEAN_02312	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IFMEFEAN_02313	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IFMEFEAN_02314	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IFMEFEAN_02315	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IFMEFEAN_02316	7.73e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
IFMEFEAN_02317	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFMEFEAN_02318	3.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IFMEFEAN_02319	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IFMEFEAN_02320	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IFMEFEAN_02321	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
IFMEFEAN_02322	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IFMEFEAN_02323	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IFMEFEAN_02324	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IFMEFEAN_02325	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IFMEFEAN_02326	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IFMEFEAN_02327	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IFMEFEAN_02328	5.86e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IFMEFEAN_02329	3.88e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IFMEFEAN_02330	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IFMEFEAN_02331	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IFMEFEAN_02332	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IFMEFEAN_02333	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IFMEFEAN_02334	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IFMEFEAN_02335	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IFMEFEAN_02336	4.64e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IFMEFEAN_02337	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IFMEFEAN_02338	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IFMEFEAN_02339	3.78e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IFMEFEAN_02340	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
IFMEFEAN_02341	2.23e-56	yqfB	-	-	-	-	-	-	-
IFMEFEAN_02342	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IFMEFEAN_02343	8.52e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IFMEFEAN_02344	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IFMEFEAN_02346	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IFMEFEAN_02347	1.75e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IFMEFEAN_02348	3.34e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IFMEFEAN_02349	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IFMEFEAN_02350	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IFMEFEAN_02351	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
IFMEFEAN_02352	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IFMEFEAN_02353	6.07e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IFMEFEAN_02354	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IFMEFEAN_02355	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
IFMEFEAN_02356	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IFMEFEAN_02357	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IFMEFEAN_02358	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IFMEFEAN_02359	2.29e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IFMEFEAN_02360	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IFMEFEAN_02361	1.98e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IFMEFEAN_02362	7.29e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IFMEFEAN_02363	1.01e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IFMEFEAN_02364	1.05e-48	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IFMEFEAN_02365	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IFMEFEAN_02366	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IFMEFEAN_02367	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IFMEFEAN_02368	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IFMEFEAN_02369	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IFMEFEAN_02370	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IFMEFEAN_02371	2.38e-80	yqfX	-	-	S	-	-	-	membrane
IFMEFEAN_02372	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IFMEFEAN_02373	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IFMEFEAN_02374	1.12e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IFMEFEAN_02375	2.36e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IFMEFEAN_02376	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IFMEFEAN_02377	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IFMEFEAN_02378	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IFMEFEAN_02379	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IFMEFEAN_02380	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IFMEFEAN_02381	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IFMEFEAN_02382	1.14e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFMEFEAN_02383	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFMEFEAN_02384	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
IFMEFEAN_02385	2.81e-67	yqzD	-	-	-	-	-	-	-
IFMEFEAN_02387	1.94e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
IFMEFEAN_02388	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IFMEFEAN_02389	4.62e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IFMEFEAN_02390	3.38e-14	yqgO	-	-	-	-	-	-	-
IFMEFEAN_02391	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IFMEFEAN_02392	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IFMEFEAN_02393	3.28e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IFMEFEAN_02394	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IFMEFEAN_02395	3.55e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IFMEFEAN_02396	2.69e-256	yqgU	-	-	-	-	-	-	-
IFMEFEAN_02397	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
IFMEFEAN_02398	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IFMEFEAN_02399	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IFMEFEAN_02400	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IFMEFEAN_02401	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IFMEFEAN_02402	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
IFMEFEAN_02403	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IFMEFEAN_02404	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_02405	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IFMEFEAN_02406	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IFMEFEAN_02407	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IFMEFEAN_02408	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IFMEFEAN_02409	2.51e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IFMEFEAN_02410	4.39e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMEFEAN_02411	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMEFEAN_02412	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFMEFEAN_02413	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IFMEFEAN_02414	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMEFEAN_02415	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IFMEFEAN_02416	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IFMEFEAN_02417	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IFMEFEAN_02418	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IFMEFEAN_02419	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IFMEFEAN_02420	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IFMEFEAN_02421	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IFMEFEAN_02422	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IFMEFEAN_02423	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IFMEFEAN_02424	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IFMEFEAN_02425	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IFMEFEAN_02426	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IFMEFEAN_02427	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IFMEFEAN_02428	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFMEFEAN_02429	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IFMEFEAN_02430	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IFMEFEAN_02431	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IFMEFEAN_02432	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IFMEFEAN_02433	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IFMEFEAN_02434	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IFMEFEAN_02435	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IFMEFEAN_02436	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IFMEFEAN_02437	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IFMEFEAN_02438	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IFMEFEAN_02439	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IFMEFEAN_02440	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IFMEFEAN_02441	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IFMEFEAN_02442	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IFMEFEAN_02443	1.83e-230	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IFMEFEAN_02444	1.36e-285	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IFMEFEAN_02445	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IFMEFEAN_02446	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IFMEFEAN_02447	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IFMEFEAN_02448	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IFMEFEAN_02449	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMEFEAN_02450	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFMEFEAN_02451	2.43e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IFMEFEAN_02452	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IFMEFEAN_02453	1.64e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IFMEFEAN_02454	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IFMEFEAN_02455	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IFMEFEAN_02456	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IFMEFEAN_02457	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IFMEFEAN_02458	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IFMEFEAN_02459	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IFMEFEAN_02460	8.65e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFMEFEAN_02461	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IFMEFEAN_02462	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IFMEFEAN_02463	5.46e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IFMEFEAN_02464	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IFMEFEAN_02465	1.82e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IFMEFEAN_02466	3.02e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IFMEFEAN_02467	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IFMEFEAN_02468	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IFMEFEAN_02469	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IFMEFEAN_02470	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IFMEFEAN_02471	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IFMEFEAN_02472	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IFMEFEAN_02473	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IFMEFEAN_02474	6.1e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IFMEFEAN_02475	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IFMEFEAN_02476	3.44e-142	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IFMEFEAN_02477	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
IFMEFEAN_02478	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02479	8.71e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IFMEFEAN_02480	5.32e-242	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IFMEFEAN_02481	9.94e-120	yisT	-	-	S	-	-	-	DinB family
IFMEFEAN_02482	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
IFMEFEAN_02483	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_02484	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IFMEFEAN_02485	1.52e-197	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IFMEFEAN_02486	1.77e-96	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_02487	2.95e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_02488	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IFMEFEAN_02489	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IFMEFEAN_02490	3.91e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IFMEFEAN_02491	2.41e-121	-	-	-	-	-	-	-	-
IFMEFEAN_02492	1.42e-218	-	-	-	-	-	-	-	-
IFMEFEAN_02493	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IFMEFEAN_02494	8.46e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IFMEFEAN_02495	2.9e-118	-	-	-	-	-	-	-	-
IFMEFEAN_02496	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
IFMEFEAN_02497	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IFMEFEAN_02498	4.16e-198	yitS	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02499	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IFMEFEAN_02500	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IFMEFEAN_02501	7.41e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IFMEFEAN_02502	1.92e-08	-	-	-	-	-	-	-	-
IFMEFEAN_02503	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IFMEFEAN_02504	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IFMEFEAN_02505	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IFMEFEAN_02506	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
IFMEFEAN_02507	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IFMEFEAN_02508	5.71e-69	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IFMEFEAN_02509	1.68e-37	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IFMEFEAN_02510	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IFMEFEAN_02511	1.37e-290	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IFMEFEAN_02512	1.81e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IFMEFEAN_02513	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IFMEFEAN_02514	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IFMEFEAN_02515	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IFMEFEAN_02516	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IFMEFEAN_02517	2.68e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IFMEFEAN_02518	1.32e-24	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
IFMEFEAN_02519	1.25e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMEFEAN_02521	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IFMEFEAN_02522	1.41e-264	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IFMEFEAN_02523	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IFMEFEAN_02524	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IFMEFEAN_02525	1.34e-74	-	-	-	-	-	-	-	-
IFMEFEAN_02526	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IFMEFEAN_02527	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IFMEFEAN_02528	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02529	3.27e-184	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_02530	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IFMEFEAN_02531	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IFMEFEAN_02532	3.26e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IFMEFEAN_02533	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_02534	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMEFEAN_02535	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
IFMEFEAN_02536	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IFMEFEAN_02537	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02538	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IFMEFEAN_02539	4.69e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IFMEFEAN_02540	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_02541	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_02542	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_02543	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IFMEFEAN_02544	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IFMEFEAN_02546	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IFMEFEAN_02547	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IFMEFEAN_02548	2.09e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_02549	5.23e-274	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IFMEFEAN_02550	1.33e-152	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IFMEFEAN_02551	5.28e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IFMEFEAN_02552	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IFMEFEAN_02553	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IFMEFEAN_02555	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IFMEFEAN_02556	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IFMEFEAN_02557	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IFMEFEAN_02558	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IFMEFEAN_02559	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IFMEFEAN_02560	1.13e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IFMEFEAN_02561	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IFMEFEAN_02562	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IFMEFEAN_02563	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IFMEFEAN_02565	5e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IFMEFEAN_02566	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IFMEFEAN_02567	5.17e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IFMEFEAN_02568	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_02569	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IFMEFEAN_02570	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IFMEFEAN_02571	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IFMEFEAN_02572	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IFMEFEAN_02573	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IFMEFEAN_02574	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IFMEFEAN_02575	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFMEFEAN_02576	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFMEFEAN_02577	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IFMEFEAN_02578	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFMEFEAN_02579	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IFMEFEAN_02580	3.19e-263	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IFMEFEAN_02581	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
IFMEFEAN_02582	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IFMEFEAN_02583	8.42e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
IFMEFEAN_02584	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IFMEFEAN_02585	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IFMEFEAN_02586	4.28e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IFMEFEAN_02587	7.9e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IFMEFEAN_02588	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IFMEFEAN_02589	3.05e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IFMEFEAN_02590	2.52e-61	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IFMEFEAN_02591	1.46e-87	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IFMEFEAN_02592	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IFMEFEAN_02593	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IFMEFEAN_02594	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IFMEFEAN_02595	4.56e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IFMEFEAN_02596	3.57e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IFMEFEAN_02597	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IFMEFEAN_02598	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
IFMEFEAN_02599	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IFMEFEAN_02600	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IFMEFEAN_02601	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IFMEFEAN_02603	1.53e-149	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IFMEFEAN_02604	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IFMEFEAN_02605	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IFMEFEAN_02606	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_02607	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IFMEFEAN_02608	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IFMEFEAN_02610	2e-204	ytxC	-	-	S	-	-	-	YtxC-like family
IFMEFEAN_02611	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IFMEFEAN_02612	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IFMEFEAN_02613	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IFMEFEAN_02614	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IFMEFEAN_02615	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IFMEFEAN_02616	9.99e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IFMEFEAN_02617	1.15e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02618	1.6e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IFMEFEAN_02619	4.54e-205	ytbE	-	-	S	-	-	-	reductase
IFMEFEAN_02620	9.8e-22	-	-	-	-	-	-	-	-
IFMEFEAN_02621	6.22e-224	-	-	-	L	-	-	-	Replication protein
IFMEFEAN_02622	1.12e-154	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IFMEFEAN_02625	6.29e-100	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02626	9.8e-302	pre	-	-	D	-	-	-	plasmid recombination enzyme
IFMEFEAN_02628	8.23e-39	-	-	-	-	-	-	-	-
IFMEFEAN_02629	4.78e-32	-	-	-	-	-	-	-	-
IFMEFEAN_02630	3.02e-117	-	-	-	L	-	-	-	Replication protein
IFMEFEAN_02632	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IFMEFEAN_02633	3.35e-63	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IFMEFEAN_02634	3.92e-99	-	-	-	S	-	-	-	Bacterial PH domain
IFMEFEAN_02635	4.27e-128	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IFMEFEAN_02636	1.04e-32	-	-	-	K	-	-	-	sequence-specific DNA binding
IFMEFEAN_02637	1.94e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_02639	1.64e-64	-	-	-	S	-	-	-	DNA binding
IFMEFEAN_02640	2.69e-88	-	-	-	-	-	-	-	-
IFMEFEAN_02645	1.55e-192	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
IFMEFEAN_02646	3.08e-149	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
IFMEFEAN_02647	3.87e-45	yqaL	-	-	L	-	-	-	DnaD domain protein
IFMEFEAN_02648	1.19e-162	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IFMEFEAN_02651	3.86e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
IFMEFEAN_02653	1.65e-30	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IFMEFEAN_02658	3.72e-91	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IFMEFEAN_02659	5.2e-19	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02660	4.91e-53	-	-	-	-	-	-	-	-
IFMEFEAN_02664	9.72e-112	yqaS	-	-	L	-	-	-	DNA packaging
IFMEFEAN_02665	2.19e-234	-	-	-	S	-	-	-	Terminase-like family
IFMEFEAN_02666	2.27e-195	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
IFMEFEAN_02667	3.28e-79	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
IFMEFEAN_02668	8.27e-157	-	-	-	S	-	-	-	Phage capsid family
IFMEFEAN_02670	2.67e-40	-	-	-	S	-	-	-	Phage Mu protein F like protein
IFMEFEAN_02672	8.09e-60	-	-	-	-	-	-	-	-
IFMEFEAN_02674	7.25e-41	-	-	-	-	-	-	-	-
IFMEFEAN_02675	2.37e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
IFMEFEAN_02676	8.46e-46	-	-	-	-	-	-	-	-
IFMEFEAN_02677	2.87e-19	-	-	-	-	-	-	-	-
IFMEFEAN_02678	1.7e-160	-	-	-	N	-	-	-	phage tail tape measure protein
IFMEFEAN_02679	6.22e-47	-	-	-	M	-	-	-	LysM domain
IFMEFEAN_02680	1.13e-41	-	-	-	-	-	-	-	-
IFMEFEAN_02681	3.69e-111	-	-	-	-	-	-	-	-
IFMEFEAN_02683	6.43e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IFMEFEAN_02684	1.84e-130	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
IFMEFEAN_02685	1.22e-78	-	-	-	-	-	-	-	-
IFMEFEAN_02686	2.68e-22	-	-	-	-	-	-	-	-
IFMEFEAN_02687	4.39e-12	-	-	-	-	-	-	-	-
IFMEFEAN_02689	4.24e-122	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
IFMEFEAN_02690	7.72e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IFMEFEAN_02691	1.25e-38	xhlB	-	-	S	-	-	-	SPP1 phage holin
IFMEFEAN_02692	4.12e-158	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IFMEFEAN_02694	1.31e-70	-	-	-	-	-	-	-	-
IFMEFEAN_02695	1.06e-60	-	-	-	S	-	-	-	YolD-like protein
IFMEFEAN_02696	3.74e-206	-	-	-	L	-	-	-	Recombinase
IFMEFEAN_02697	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IFMEFEAN_02698	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
IFMEFEAN_02699	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IFMEFEAN_02700	6.7e-139	yvgT	-	-	S	-	-	-	membrane
IFMEFEAN_02702	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IFMEFEAN_02703	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IFMEFEAN_02704	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IFMEFEAN_02705	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IFMEFEAN_02706	9.32e-112	yvgO	-	-	-	-	-	-	-
IFMEFEAN_02707	6.19e-201	yvgN	-	-	S	-	-	-	reductase
IFMEFEAN_02708	1.01e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IFMEFEAN_02709	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IFMEFEAN_02710	2.97e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IFMEFEAN_02711	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IFMEFEAN_02712	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IFMEFEAN_02713	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IFMEFEAN_02714	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IFMEFEAN_02716	2.57e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IFMEFEAN_02717	4.04e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_02718	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_02719	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMEFEAN_02720	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
IFMEFEAN_02721	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_02722	2.21e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IFMEFEAN_02723	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IFMEFEAN_02724	3.76e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IFMEFEAN_02725	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
IFMEFEAN_02726	1.12e-124	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IFMEFEAN_02727	5.07e-32	-	-	-	-	-	-	-	-
IFMEFEAN_02728	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_02729	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IFMEFEAN_02730	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IFMEFEAN_02731	2.89e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_02732	7.32e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IFMEFEAN_02733	7.73e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFMEFEAN_02734	5.43e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IFMEFEAN_02735	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IFMEFEAN_02736	1.53e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_02737	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IFMEFEAN_02738	2.85e-142	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IFMEFEAN_02739	8.15e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IFMEFEAN_02740	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IFMEFEAN_02741	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_02742	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_02743	5.54e-234	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IFMEFEAN_02744	7.95e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IFMEFEAN_02745	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IFMEFEAN_02746	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IFMEFEAN_02747	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IFMEFEAN_02748	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02749	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_02750	6.4e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_02751	2.17e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IFMEFEAN_02752	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IFMEFEAN_02753	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
IFMEFEAN_02754	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02755	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IFMEFEAN_02756	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IFMEFEAN_02757	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IFMEFEAN_02758	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IFMEFEAN_02759	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IFMEFEAN_02760	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IFMEFEAN_02761	2.65e-60	ccpB	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02762	2.14e-154	ccpB	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02763	4.69e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_02764	3.01e-126	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IFMEFEAN_02765	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
IFMEFEAN_02766	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IFMEFEAN_02767	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IFMEFEAN_02768	3.47e-108	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
IFMEFEAN_02769	1.67e-134	yyaP	-	-	H	-	-	-	RibD C-terminal domain
IFMEFEAN_02770	2.28e-48	-	-	-	S	-	-	-	YjbR
IFMEFEAN_02771	3.81e-87	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IFMEFEAN_02772	1.55e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IFMEFEAN_02773	4.18e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_02774	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
IFMEFEAN_02775	4.41e-105	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IFMEFEAN_02776	3.87e-132	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_02777	6.02e-157	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
IFMEFEAN_02778	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
IFMEFEAN_02779	2.05e-183	-	-	-	-	-	-	-	-
IFMEFEAN_02780	7.24e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IFMEFEAN_02781	7.94e-200	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_02782	5.21e-70	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_02784	3.19e-90	-	-	-	-	-	-	-	-
IFMEFEAN_02785	2.83e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IFMEFEAN_02786	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02787	1.71e-67	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IFMEFEAN_02788	6.16e-20	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IFMEFEAN_02790	4.15e-120	yybS	-	-	S	-	-	-	membrane
IFMEFEAN_02791	1.14e-34	yybS	-	-	S	-	-	-	membrane
IFMEFEAN_02792	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IFMEFEAN_02793	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IFMEFEAN_02794	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IFMEFEAN_02795	1.15e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IFMEFEAN_02796	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
IFMEFEAN_02798	2.87e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IFMEFEAN_02799	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IFMEFEAN_02800	3.17e-97	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_02801	3.02e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IFMEFEAN_02806	2.07e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_02807	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_02808	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02809	3.44e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02810	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IFMEFEAN_02811	2.32e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IFMEFEAN_02812	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IFMEFEAN_02813	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
IFMEFEAN_02814	3.8e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IFMEFEAN_02815	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IFMEFEAN_02816	4.85e-119	-	-	-	-	-	-	-	-
IFMEFEAN_02817	5.82e-20	-	-	-	-	-	-	-	-
IFMEFEAN_02818	1.01e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IFMEFEAN_02819	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IFMEFEAN_02820	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IFMEFEAN_02822	2.06e-204	-	-	-	S	-	-	-	aspartate phosphatase
IFMEFEAN_02823	1.17e-18	-	-	-	S	-	-	-	aspartate phosphatase
IFMEFEAN_02824	4.15e-108	yycN	-	-	K	-	-	-	Acetyltransferase
IFMEFEAN_02825	3.06e-156	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IFMEFEAN_02826	2.71e-260	yycP	-	-	-	-	-	-	-
IFMEFEAN_02827	4.53e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IFMEFEAN_02829	2.12e-296	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IFMEFEAN_02830	1.64e-89	-	-	-	-	-	-	-	-
IFMEFEAN_02832	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IFMEFEAN_02834	3.91e-135	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
IFMEFEAN_02835	1.59e-65	-	-	-	L	-	-	-	Transposase
IFMEFEAN_02836	3.17e-176	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
IFMEFEAN_02837	3.99e-53	-	-	-	-	-	-	-	-
IFMEFEAN_02839	1.07e-57	-	-	-	S	-	-	-	transposition, DNA-mediated
IFMEFEAN_02840	6.23e-148	-	-	-	S	-	-	-	HTH-like domain
IFMEFEAN_02841	0.0	-	-	-	L	-	-	-	AAA ATPase domain
IFMEFEAN_02842	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
IFMEFEAN_02843	0.0	-	-	-	V	-	-	-	Abi-like protein
IFMEFEAN_02844	6.83e-45	-	-	-	-	-	-	-	-
IFMEFEAN_02845	5.47e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_02846	6.6e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IFMEFEAN_02847	4.7e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IFMEFEAN_02848	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IFMEFEAN_02849	1.8e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IFMEFEAN_02850	2.01e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
IFMEFEAN_02851	5.05e-186	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IFMEFEAN_02852	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IFMEFEAN_02853	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IFMEFEAN_02854	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IFMEFEAN_02855	7.22e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IFMEFEAN_02856	5.2e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IFMEFEAN_02857	1.01e-223	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IFMEFEAN_02858	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IFMEFEAN_02859	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IFMEFEAN_02860	1.17e-22	degR	-	-	-	-	-	-	-
IFMEFEAN_02861	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IFMEFEAN_02862	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
IFMEFEAN_02863	1.56e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IFMEFEAN_02864	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IFMEFEAN_02865	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IFMEFEAN_02866	2.59e-05	-	-	-	-	ko:K06429	-	ko00000	-
IFMEFEAN_02867	1.12e-94	ypcP	-	-	L	-	-	-	5'3' exonuclease
IFMEFEAN_02868	1e-81	ypcP	-	-	L	-	-	-	5'3' exonuclease
IFMEFEAN_02869	1.08e-11	-	-	-	-	-	-	-	-
IFMEFEAN_02870	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IFMEFEAN_02871	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IFMEFEAN_02872	1.36e-112	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IFMEFEAN_02873	4.08e-41	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IFMEFEAN_02874	1.49e-201	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IFMEFEAN_02875	8.61e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IFMEFEAN_02876	9.13e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IFMEFEAN_02877	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IFMEFEAN_02878	2.36e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IFMEFEAN_02879	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
IFMEFEAN_02880	1.15e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
IFMEFEAN_02881	2.24e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IFMEFEAN_02882	7.26e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IFMEFEAN_02883	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_02884	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IFMEFEAN_02886	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IFMEFEAN_02887	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IFMEFEAN_02888	1.39e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IFMEFEAN_02889	2.81e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IFMEFEAN_02890	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IFMEFEAN_02891	2.59e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IFMEFEAN_02892	2.41e-92	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IFMEFEAN_02893	8.36e-66	yppG	-	-	S	-	-	-	YppG-like protein
IFMEFEAN_02894	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
IFMEFEAN_02895	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
IFMEFEAN_02898	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IFMEFEAN_02899	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IFMEFEAN_02900	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IFMEFEAN_02901	1.43e-121	ypoC	-	-	-	-	-	-	-
IFMEFEAN_02902	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IFMEFEAN_02903	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IFMEFEAN_02904	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IFMEFEAN_02905	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IFMEFEAN_02906	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_02907	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IFMEFEAN_02908	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IFMEFEAN_02909	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IFMEFEAN_02910	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IFMEFEAN_02911	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IFMEFEAN_02912	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IFMEFEAN_02913	1.83e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IFMEFEAN_02914	7.01e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IFMEFEAN_02915	2.21e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IFMEFEAN_02916	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IFMEFEAN_02917	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IFMEFEAN_02918	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IFMEFEAN_02919	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IFMEFEAN_02920	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
IFMEFEAN_02921	1.15e-125	ypjA	-	-	S	-	-	-	membrane
IFMEFEAN_02922	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IFMEFEAN_02923	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IFMEFEAN_02924	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IFMEFEAN_02925	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IFMEFEAN_02926	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IFMEFEAN_02927	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IFMEFEAN_02928	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IFMEFEAN_02929	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IFMEFEAN_02930	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IFMEFEAN_02931	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IFMEFEAN_02932	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IFMEFEAN_02933	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IFMEFEAN_02934	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IFMEFEAN_02935	2.37e-227	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IFMEFEAN_02936	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IFMEFEAN_02937	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IFMEFEAN_02938	3.86e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IFMEFEAN_02939	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IFMEFEAN_02940	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IFMEFEAN_02941	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IFMEFEAN_02942	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IFMEFEAN_02943	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IFMEFEAN_02944	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IFMEFEAN_02945	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IFMEFEAN_02946	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IFMEFEAN_02947	5.93e-85	hxlR	-	-	K	-	-	-	transcriptional
IFMEFEAN_02948	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IFMEFEAN_02949	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IFMEFEAN_02950	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_02951	3.11e-73	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_02952	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IFMEFEAN_02953	3.36e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IFMEFEAN_02954	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMEFEAN_02955	8.9e-22	-	-	-	S	-	-	-	AAA domain
IFMEFEAN_02956	2.13e-113	-	-	-	S	-	-	-	AAA domain
IFMEFEAN_02957	2.49e-27	-	-	-	-	-	-	-	-
IFMEFEAN_02958	1.06e-57	-	-	-	K	-	-	-	MarR family
IFMEFEAN_02959	1.38e-66	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IFMEFEAN_02960	1.11e-96	yckC	-	-	S	-	-	-	membrane
IFMEFEAN_02963	8.47e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IFMEFEAN_02964	3.35e-146	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IFMEFEAN_02965	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
IFMEFEAN_02966	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
IFMEFEAN_02967	2.12e-87	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IFMEFEAN_02968	2.21e-150	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
IFMEFEAN_02969	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IFMEFEAN_02970	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
IFMEFEAN_02971	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IFMEFEAN_02972	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IFMEFEAN_02973	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IFMEFEAN_02974	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IFMEFEAN_02975	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IFMEFEAN_02976	3.3e-200	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
IFMEFEAN_02977	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
IFMEFEAN_02978	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
IFMEFEAN_02979	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IFMEFEAN_02980	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IFMEFEAN_02981	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IFMEFEAN_02982	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IFMEFEAN_02983	3.69e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IFMEFEAN_02984	1.1e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IFMEFEAN_02985	5.64e-228	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
IFMEFEAN_02986	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IFMEFEAN_02987	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IFMEFEAN_02988	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
IFMEFEAN_02989	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IFMEFEAN_02990	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IFMEFEAN_02991	2.67e-154	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_02992	4.4e-134	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IFMEFEAN_02993	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IFMEFEAN_02994	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IFMEFEAN_02995	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IFMEFEAN_02996	1.31e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IFMEFEAN_02997	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IFMEFEAN_02998	2.72e-105	ycgB	-	-	-	-	-	-	-
IFMEFEAN_02999	0.0	ycgA	-	-	S	-	-	-	Membrane
IFMEFEAN_03000	4.44e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IFMEFEAN_03001	4.73e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IFMEFEAN_03002	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IFMEFEAN_03003	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IFMEFEAN_03004	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMEFEAN_03005	0.0	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
IFMEFEAN_03006	2.19e-86	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
IFMEFEAN_03007	3.83e-131	-	-	-	V	ko:K19173	-	ko00000,ko02048	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IFMEFEAN_03008	2.86e-193	-	-	-	S	ko:K19169	-	ko00000,ko02048	DNA-sulfur modification-associated
IFMEFEAN_03009	8.5e-272	-	-	-	EH	ko:K19170	-	ko00000,ko02048	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
IFMEFEAN_03010	3.14e-187	-	-	-	EL	ko:K19171	-	ko00000,ko02048	AAA domain
IFMEFEAN_03011	1.9e-41	-	-	-	S	-	-	-	DNA sulphur modification protein DndE
IFMEFEAN_03012	8.04e-181	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
IFMEFEAN_03013	1.72e-255	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IFMEFEAN_03014	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IFMEFEAN_03015	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IFMEFEAN_03016	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IFMEFEAN_03017	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IFMEFEAN_03018	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IFMEFEAN_03019	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IFMEFEAN_03020	2.53e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IFMEFEAN_03021	1.07e-81	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFMEFEAN_03022	6.56e-107	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFMEFEAN_03023	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IFMEFEAN_03024	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IFMEFEAN_03025	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IFMEFEAN_03026	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IFMEFEAN_03027	7.67e-177	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IFMEFEAN_03028	1.65e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_03029	1.53e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IFMEFEAN_03030	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_03031	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_03032	6.38e-229	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IFMEFEAN_03033	4.58e-68	yccK	-	-	C	-	-	-	Aldo keto reductase
IFMEFEAN_03034	2.9e-28	yccK	-	-	C	-	-	-	Aldo keto reductase
IFMEFEAN_03035	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IFMEFEAN_03036	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IFMEFEAN_03037	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IFMEFEAN_03038	6.18e-213	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IFMEFEAN_03039	7.13e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IFMEFEAN_03040	4.32e-78	-	-	-	S	-	-	-	RDD family
IFMEFEAN_03041	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IFMEFEAN_03042	8.02e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IFMEFEAN_03043	7.64e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IFMEFEAN_03044	1.45e-301	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IFMEFEAN_03045	1.39e-258	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IFMEFEAN_03046	4.68e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IFMEFEAN_03047	3.61e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IFMEFEAN_03048	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IFMEFEAN_03049	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IFMEFEAN_03050	3.83e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
IFMEFEAN_03051	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IFMEFEAN_03052	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IFMEFEAN_03053	3.77e-97	-	-	-	S	-	-	-	Bacterial PH domain
IFMEFEAN_03054	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IFMEFEAN_03055	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IFMEFEAN_03056	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IFMEFEAN_03057	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IFMEFEAN_03058	4.32e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IFMEFEAN_03059	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFMEFEAN_03060	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IFMEFEAN_03061	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IFMEFEAN_03062	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IFMEFEAN_03063	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IFMEFEAN_03064	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IFMEFEAN_03065	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IFMEFEAN_03066	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFMEFEAN_03067	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFMEFEAN_03068	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IFMEFEAN_03069	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IFMEFEAN_03070	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IFMEFEAN_03071	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IFMEFEAN_03072	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IFMEFEAN_03073	8.86e-237	ygaE	-	-	S	-	-	-	Membrane
IFMEFEAN_03074	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IFMEFEAN_03075	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IFMEFEAN_03076	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
IFMEFEAN_03077	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IFMEFEAN_03078	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_03079	1.73e-48	yfhS	-	-	-	-	-	-	-
IFMEFEAN_03080	1.99e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IFMEFEAN_03081	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IFMEFEAN_03082	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IFMEFEAN_03083	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IFMEFEAN_03084	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
IFMEFEAN_03085	6.3e-66	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IFMEFEAN_03086	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IFMEFEAN_03087	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
IFMEFEAN_03088	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
IFMEFEAN_03089	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
IFMEFEAN_03090	3.26e-72	-	-	-	L	-	-	-	transposase activity
IFMEFEAN_03101	4.03e-07	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	DNA segregation ATPase FtsK SpoIIIE and related proteins
IFMEFEAN_03106	8.34e-26	-	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
IFMEFEAN_03107	6.48e-34	-	-	-	S	-	-	-	Repressor of ComK
IFMEFEAN_03111	1.88e-51	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IFMEFEAN_03112	6.99e-09	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IFMEFEAN_03113	1.63e-09	-	-	-	-	-	-	-	-
IFMEFEAN_03116	1.81e-37	bhlA	-	-	S	-	-	-	BhlA holin family
IFMEFEAN_03117	3.19e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
IFMEFEAN_03118	7.81e-167	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IFMEFEAN_03119	8.88e-87	-	-	-	S	-	-	-	Immunity protein 70
IFMEFEAN_03120	6.57e-233	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IFMEFEAN_03122	7.52e-55	-	-	-	S	-	-	-	protein domain associated with
IFMEFEAN_03124	6.75e-38	-	-	-	K	-	-	-	Helix-turn-helix domain
IFMEFEAN_03126	5.85e-35	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
IFMEFEAN_03130	1.17e-148	-	-	-	-	-	-	-	-
IFMEFEAN_03131	5.53e-175	-	-	-	-	-	-	-	-
IFMEFEAN_03132	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IFMEFEAN_03133	2.5e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IFMEFEAN_03134	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IFMEFEAN_03135	4.95e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IFMEFEAN_03136	8.88e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IFMEFEAN_03137	3.64e-228	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IFMEFEAN_03138	3.21e-167	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IFMEFEAN_03139	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IFMEFEAN_03140	4.11e-183	-	-	-	S	-	-	-	Ion transport 2 domain protein
IFMEFEAN_03141	1.91e-33	-	-	-	S	-	-	-	Ion transport 2 domain protein
IFMEFEAN_03142	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_03143	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IFMEFEAN_03144	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
IFMEFEAN_03145	1.62e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IFMEFEAN_03146	9.38e-95	ytwI	-	-	S	-	-	-	membrane
IFMEFEAN_03147	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IFMEFEAN_03148	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IFMEFEAN_03149	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IFMEFEAN_03150	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IFMEFEAN_03151	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IFMEFEAN_03152	5.96e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IFMEFEAN_03153	1.21e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IFMEFEAN_03154	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IFMEFEAN_03155	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IFMEFEAN_03156	5.12e-112	ytrI	-	-	-	-	-	-	-
IFMEFEAN_03157	1.15e-39	-	-	-	-	-	-	-	-
IFMEFEAN_03158	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IFMEFEAN_03159	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
IFMEFEAN_03160	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IFMEFEAN_03161	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IFMEFEAN_03162	8.04e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_03164	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IFMEFEAN_03165	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IFMEFEAN_03166	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IFMEFEAN_03167	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFMEFEAN_03169	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IFMEFEAN_03170	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IFMEFEAN_03171	5.02e-90	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IFMEFEAN_03172	6.29e-144	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IFMEFEAN_03173	8.23e-112	yteJ	-	-	S	-	-	-	RDD family
IFMEFEAN_03174	3.25e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IFMEFEAN_03175	8.04e-188	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IFMEFEAN_03176	2.23e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
IFMEFEAN_03177	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
IFMEFEAN_03178	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_03179	8.03e-81	ymzB	-	-	-	-	-	-	-
IFMEFEAN_03180	1.96e-209	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IFMEFEAN_03181	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IFMEFEAN_03183	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
IFMEFEAN_03184	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IFMEFEAN_03185	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
IFMEFEAN_03186	2.45e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IFMEFEAN_03188	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
IFMEFEAN_03189	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IFMEFEAN_03190	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IFMEFEAN_03191	1.63e-31	-	-	-	-	-	-	-	-
IFMEFEAN_03192	1.2e-30	ymzA	-	-	-	-	-	-	-
IFMEFEAN_03193	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IFMEFEAN_03194	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFMEFEAN_03195	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFMEFEAN_03196	2.24e-141	-	-	-	-	-	-	-	-
IFMEFEAN_03197	1.16e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_03198	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IFMEFEAN_03199	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IFMEFEAN_03200	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IFMEFEAN_03201	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IFMEFEAN_03202	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IFMEFEAN_03203	3.69e-32	-	-	-	-	-	-	-	-
IFMEFEAN_03204	1.68e-53	-	-	-	-	-	-	-	-
IFMEFEAN_03205	4.6e-309	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
IFMEFEAN_03207	1.68e-13	-	-	-	-	-	-	-	-
IFMEFEAN_03209	1.46e-105	-	-	-	-	-	-	-	-
IFMEFEAN_03210	4.13e-51	-	-	-	-	-	-	-	-
IFMEFEAN_03211	4.13e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
IFMEFEAN_03212	9.3e-51	ynaC	-	-	-	-	-	-	-
IFMEFEAN_03213	3.65e-81	ynaC	-	-	-	-	-	-	-
IFMEFEAN_03214	1.77e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IFMEFEAN_03216	0.0	-	-	-	O	-	-	-	Peptidase family M48
IFMEFEAN_03217	1.09e-307	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IFMEFEAN_03218	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IFMEFEAN_03219	2.35e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IFMEFEAN_03220	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IFMEFEAN_03221	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IFMEFEAN_03222	3.73e-202	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IFMEFEAN_03223	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IFMEFEAN_03224	2.6e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_03225	1.93e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
IFMEFEAN_03226	1.63e-39	-	-	-	-	-	-	-	-
IFMEFEAN_03227	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IFMEFEAN_03228	3.33e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_03229	1.14e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IFMEFEAN_03230	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMEFEAN_03231	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IFMEFEAN_03232	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IFMEFEAN_03233	1.05e-26	yxzF	-	-	-	-	-	-	-
IFMEFEAN_03234	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IFMEFEAN_03235	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IFMEFEAN_03236	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMEFEAN_03237	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_03238	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IFMEFEAN_03239	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IFMEFEAN_03240	3.56e-43	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03241	2.19e-07	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03242	1.5e-60	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03243	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IFMEFEAN_03244	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_03245	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IFMEFEAN_03246	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_03248	5.95e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IFMEFEAN_03249	9.01e-218	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IFMEFEAN_03250	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IFMEFEAN_03251	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IFMEFEAN_03252	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IFMEFEAN_03253	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IFMEFEAN_03254	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IFMEFEAN_03255	1.06e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFMEFEAN_03256	4.35e-32	yqzJ	-	-	-	-	-	-	-
IFMEFEAN_03257	1.47e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFMEFEAN_03258	1.57e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
IFMEFEAN_03259	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IFMEFEAN_03260	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IFMEFEAN_03261	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IFMEFEAN_03263	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03264	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IFMEFEAN_03265	1.49e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IFMEFEAN_03266	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IFMEFEAN_03267	4.79e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IFMEFEAN_03268	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IFMEFEAN_03269	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IFMEFEAN_03270	1.79e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_03271	4.31e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
IFMEFEAN_03272	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IFMEFEAN_03273	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IFMEFEAN_03274	1.11e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IFMEFEAN_03275	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IFMEFEAN_03276	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IFMEFEAN_03277	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IFMEFEAN_03278	1.18e-196	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IFMEFEAN_03279	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IFMEFEAN_03280	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IFMEFEAN_03281	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IFMEFEAN_03282	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IFMEFEAN_03283	3.9e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IFMEFEAN_03284	2.01e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IFMEFEAN_03285	1.19e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IFMEFEAN_03286	2.59e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IFMEFEAN_03287	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IFMEFEAN_03288	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IFMEFEAN_03289	4.74e-37	-	-	-	-	-	-	-	-
IFMEFEAN_03290	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IFMEFEAN_03292	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IFMEFEAN_03293	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IFMEFEAN_03294	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IFMEFEAN_03295	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IFMEFEAN_03296	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IFMEFEAN_03297	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IFMEFEAN_03298	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IFMEFEAN_03299	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFMEFEAN_03300	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFMEFEAN_03301	1.45e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IFMEFEAN_03302	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IFMEFEAN_03303	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03304	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IFMEFEAN_03305	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IFMEFEAN_03306	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IFMEFEAN_03307	7.6e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IFMEFEAN_03308	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IFMEFEAN_03309	3.11e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IFMEFEAN_03310	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IFMEFEAN_03311	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IFMEFEAN_03312	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IFMEFEAN_03313	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IFMEFEAN_03314	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IFMEFEAN_03315	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFMEFEAN_03316	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IFMEFEAN_03317	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IFMEFEAN_03318	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IFMEFEAN_03319	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IFMEFEAN_03320	5.18e-81	yqhP	-	-	-	-	-	-	-
IFMEFEAN_03321	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IFMEFEAN_03322	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IFMEFEAN_03323	2.63e-203	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IFMEFEAN_03324	2.51e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IFMEFEAN_03325	1.12e-134	yuaD	-	-	-	-	-	-	-
IFMEFEAN_03326	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IFMEFEAN_03327	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IFMEFEAN_03328	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IFMEFEAN_03329	5.83e-118	yuaB	-	-	-	-	-	-	-
IFMEFEAN_03330	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IFMEFEAN_03331	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
IFMEFEAN_03332	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
IFMEFEAN_03333	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IFMEFEAN_03334	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IFMEFEAN_03335	5.39e-111	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
IFMEFEAN_03337	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IFMEFEAN_03338	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
IFMEFEAN_03339	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IFMEFEAN_03340	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
IFMEFEAN_03341	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IFMEFEAN_03342	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IFMEFEAN_03343	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IFMEFEAN_03344	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
IFMEFEAN_03345	2.61e-185	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_03346	2.35e-115	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_03347	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_03348	2.02e-284	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_03349	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IFMEFEAN_03350	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IFMEFEAN_03351	5e-48	-	-	-	-	-	-	-	-
IFMEFEAN_03352	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IFMEFEAN_03353	7.23e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IFMEFEAN_03354	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IFMEFEAN_03355	2.16e-48	-	-	-	-	-	-	-	-
IFMEFEAN_03356	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IFMEFEAN_03357	1.69e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IFMEFEAN_03358	2.75e-91	yugN	-	-	S	-	-	-	YugN-like family
IFMEFEAN_03360	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IFMEFEAN_03361	1.2e-285	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IFMEFEAN_03362	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IFMEFEAN_03363	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IFMEFEAN_03364	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IFMEFEAN_03365	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IFMEFEAN_03366	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_03367	1.18e-119	yugF	-	-	I	-	-	-	Hydrolase
IFMEFEAN_03368	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
IFMEFEAN_03369	8.96e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IFMEFEAN_03370	8.4e-42	yrzR	-	-	-	-	-	-	-
IFMEFEAN_03371	2.79e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03372	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IFMEFEAN_03373	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IFMEFEAN_03374	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IFMEFEAN_03375	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IFMEFEAN_03376	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_03377	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IFMEFEAN_03378	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IFMEFEAN_03379	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IFMEFEAN_03380	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IFMEFEAN_03382	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IFMEFEAN_03383	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IFMEFEAN_03384	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IFMEFEAN_03385	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IFMEFEAN_03386	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IFMEFEAN_03387	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IFMEFEAN_03388	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IFMEFEAN_03389	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IFMEFEAN_03390	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IFMEFEAN_03391	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_03392	8.64e-145	yrbG	-	-	S	-	-	-	membrane
IFMEFEAN_03393	2.16e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IFMEFEAN_03394	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IFMEFEAN_03395	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IFMEFEAN_03396	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IFMEFEAN_03397	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IFMEFEAN_03398	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IFMEFEAN_03399	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IFMEFEAN_03400	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IFMEFEAN_03401	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
IFMEFEAN_03402	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IFMEFEAN_03403	1.91e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
IFMEFEAN_03405	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
IFMEFEAN_03407	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IFMEFEAN_03408	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IFMEFEAN_03409	5.13e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IFMEFEAN_03410	3.45e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IFMEFEAN_03411	4.41e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IFMEFEAN_03412	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IFMEFEAN_03413	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IFMEFEAN_03414	1.17e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IFMEFEAN_03415	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IFMEFEAN_03416	2.54e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IFMEFEAN_03417	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IFMEFEAN_03418	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IFMEFEAN_03419	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IFMEFEAN_03420	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IFMEFEAN_03421	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IFMEFEAN_03422	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IFMEFEAN_03423	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IFMEFEAN_03424	7.44e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IFMEFEAN_03425	4.13e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IFMEFEAN_03426	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IFMEFEAN_03427	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IFMEFEAN_03428	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IFMEFEAN_03429	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IFMEFEAN_03430	2.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IFMEFEAN_03431	2.02e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IFMEFEAN_03432	2.47e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IFMEFEAN_03433	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IFMEFEAN_03434	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IFMEFEAN_03435	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IFMEFEAN_03436	1.53e-35	-	-	-	-	-	-	-	-
IFMEFEAN_03437	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IFMEFEAN_03438	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IFMEFEAN_03439	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IFMEFEAN_03440	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IFMEFEAN_03441	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IFMEFEAN_03442	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IFMEFEAN_03443	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IFMEFEAN_03444	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IFMEFEAN_03445	4.77e-116	ysxD	-	-	-	-	-	-	-
IFMEFEAN_03446	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IFMEFEAN_03447	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IFMEFEAN_03448	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IFMEFEAN_03449	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IFMEFEAN_03450	5.98e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IFMEFEAN_03451	2.62e-238	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IFMEFEAN_03452	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IFMEFEAN_03453	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IFMEFEAN_03454	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IFMEFEAN_03455	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IFMEFEAN_03456	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IFMEFEAN_03457	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IFMEFEAN_03458	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IFMEFEAN_03459	3.28e-46	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IFMEFEAN_03460	3.36e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03461	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IFMEFEAN_03462	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IFMEFEAN_03463	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IFMEFEAN_03464	1.26e-20	yjlB	-	-	S	-	-	-	Cupin domain
IFMEFEAN_03465	4.85e-54	yjlB	-	-	S	-	-	-	Cupin domain
IFMEFEAN_03466	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IFMEFEAN_03467	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IFMEFEAN_03468	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IFMEFEAN_03469	1.13e-165	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IFMEFEAN_03470	8.14e-128	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IFMEFEAN_03471	1.03e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
IFMEFEAN_03472	1.53e-244	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IFMEFEAN_03473	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IFMEFEAN_03474	1.83e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03475	4.58e-288	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
IFMEFEAN_03476	1.15e-236	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IFMEFEAN_03477	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IFMEFEAN_03478	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IFMEFEAN_03479	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IFMEFEAN_03481	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
IFMEFEAN_03482	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
IFMEFEAN_03483	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IFMEFEAN_03484	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IFMEFEAN_03485	5.2e-132	yjaV	-	-	-	-	-	-	-
IFMEFEAN_03486	5.26e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IFMEFEAN_03487	8.86e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IFMEFEAN_03488	2.67e-38	yjzB	-	-	-	-	-	-	-
IFMEFEAN_03489	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IFMEFEAN_03490	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IFMEFEAN_03491	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IFMEFEAN_03492	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_03493	2.82e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_03494	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IFMEFEAN_03495	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_03496	8.44e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_03497	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IFMEFEAN_03498	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IFMEFEAN_03499	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IFMEFEAN_03500	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_03501	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFMEFEAN_03502	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_03503	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_03504	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMEFEAN_03505	2.77e-54	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_03506	1.41e-63	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_03507	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IFMEFEAN_03508	4.1e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IFMEFEAN_03509	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IFMEFEAN_03510	9.9e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IFMEFEAN_03511	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IFMEFEAN_03512	2.68e-28	-	-	-	-	-	-	-	-
IFMEFEAN_03513	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IFMEFEAN_03514	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IFMEFEAN_03515	3.61e-122	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IFMEFEAN_03516	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03517	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IFMEFEAN_03518	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IFMEFEAN_03519	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IFMEFEAN_03520	3.01e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IFMEFEAN_03521	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IFMEFEAN_03522	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IFMEFEAN_03523	1.91e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IFMEFEAN_03524	4.49e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IFMEFEAN_03525	1.73e-272	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IFMEFEAN_03526	2.56e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IFMEFEAN_03527	1.86e-171	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IFMEFEAN_03528	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IFMEFEAN_03529	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IFMEFEAN_03530	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IFMEFEAN_03531	2.09e-103	yjbX	-	-	S	-	-	-	Spore coat protein
IFMEFEAN_03532	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IFMEFEAN_03533	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IFMEFEAN_03534	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IFMEFEAN_03535	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
IFMEFEAN_03537	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IFMEFEAN_03540	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IFMEFEAN_03541	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IFMEFEAN_03542	6.31e-51	-	-	-	-	-	-	-	-
IFMEFEAN_03543	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_03544	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IFMEFEAN_03545	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IFMEFEAN_03546	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IFMEFEAN_03547	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IFMEFEAN_03548	6.86e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
IFMEFEAN_03549	8.25e-271	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
IFMEFEAN_03551	1.71e-48	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_03552	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_03553	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IFMEFEAN_03555	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
IFMEFEAN_03556	5.33e-85	-	-	-	-	-	-	-	-
IFMEFEAN_03557	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_03558	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_03559	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
IFMEFEAN_03560	2.09e-103	-	-	-	-	-	-	-	-
IFMEFEAN_03561	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IFMEFEAN_03562	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFMEFEAN_03563	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IFMEFEAN_03564	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFMEFEAN_03565	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFMEFEAN_03566	1.82e-18	-	-	-	-	-	-	-	-
IFMEFEAN_03567	8.74e-75	ynfC	-	-	-	-	-	-	-
IFMEFEAN_03568	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IFMEFEAN_03569	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
IFMEFEAN_03571	2.36e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IFMEFEAN_03572	5.7e-309	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IFMEFEAN_03573	8.44e-31	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IFMEFEAN_03574	1.36e-100	yngA	-	-	S	-	-	-	membrane
IFMEFEAN_03575	1.07e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IFMEFEAN_03576	1.16e-133	yngC	-	-	S	-	-	-	membrane-associated protein
IFMEFEAN_03577	1.74e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
IFMEFEAN_03578	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IFMEFEAN_03579	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IFMEFEAN_03580	1.12e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IFMEFEAN_03581	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IFMEFEAN_03582	5.62e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IFMEFEAN_03583	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IFMEFEAN_03584	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IFMEFEAN_03585	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IFMEFEAN_03586	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IFMEFEAN_03587	1.24e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IFMEFEAN_03588	2.58e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IFMEFEAN_03589	4.59e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03590	1.24e-39	ypmT	-	-	S	-	-	-	Uncharacterized ympT
IFMEFEAN_03591	1.65e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
IFMEFEAN_03592	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
IFMEFEAN_03593	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IFMEFEAN_03594	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IFMEFEAN_03595	5.51e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IFMEFEAN_03596	1.34e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IFMEFEAN_03597	4.45e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IFMEFEAN_03598	3.62e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
IFMEFEAN_03599	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
IFMEFEAN_03600	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IFMEFEAN_03601	1.97e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IFMEFEAN_03602	1.73e-13	-	-	-	-	-	-	-	-
IFMEFEAN_03603	8.16e-77	-	-	-	O	-	-	-	Papain family cysteine protease
IFMEFEAN_03605	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
IFMEFEAN_03606	3.82e-37	-	-	-	-	-	-	-	-
IFMEFEAN_03608	5.68e-58	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFMEFEAN_03610	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
IFMEFEAN_03612	1.54e-121	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMEFEAN_03613	5.98e-72	ypuD	-	-	-	-	-	-	-
IFMEFEAN_03614	3.42e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IFMEFEAN_03615	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IFMEFEAN_03616	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IFMEFEAN_03617	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IFMEFEAN_03618	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFMEFEAN_03619	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IFMEFEAN_03620	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IFMEFEAN_03621	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IFMEFEAN_03622	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IFMEFEAN_03623	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IFMEFEAN_03624	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IFMEFEAN_03625	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IFMEFEAN_03626	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IFMEFEAN_03627	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IFMEFEAN_03628	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IFMEFEAN_03629	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IFMEFEAN_03630	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_03631	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_03632	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_03633	8.11e-17	rsiX	-	-	-	-	-	-	-
IFMEFEAN_03634	2.96e-135	rsiX	-	-	-	-	-	-	-
IFMEFEAN_03635	9.27e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IFMEFEAN_03636	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFMEFEAN_03637	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IFMEFEAN_03638	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IFMEFEAN_03639	3.14e-255	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IFMEFEAN_03640	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IFMEFEAN_03641	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IFMEFEAN_03642	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
IFMEFEAN_03643	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IFMEFEAN_03644	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IFMEFEAN_03645	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IFMEFEAN_03646	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IFMEFEAN_03647	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IFMEFEAN_03648	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IFMEFEAN_03649	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IFMEFEAN_03650	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IFMEFEAN_03651	2.02e-138	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IFMEFEAN_03652	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IFMEFEAN_03653	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IFMEFEAN_03654	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IFMEFEAN_03655	2.21e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IFMEFEAN_03656	3.43e-71	yugF	-	-	I	-	-	-	Hydrolase
IFMEFEAN_03657	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IFMEFEAN_03658	3.32e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IFMEFEAN_03659	4.32e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_03660	8.36e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IFMEFEAN_03661	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IFMEFEAN_03663	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IFMEFEAN_03664	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IFMEFEAN_03665	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03666	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IFMEFEAN_03667	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IFMEFEAN_03668	1.88e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IFMEFEAN_03669	9e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IFMEFEAN_03670	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_03671	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMEFEAN_03672	1.15e-213	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IFMEFEAN_03673	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
IFMEFEAN_03674	1.42e-21	-	-	-	-	-	-	-	-
IFMEFEAN_03675	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IFMEFEAN_03676	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IFMEFEAN_03677	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IFMEFEAN_03678	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IFMEFEAN_03679	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IFMEFEAN_03680	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IFMEFEAN_03681	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IFMEFEAN_03682	9.49e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IFMEFEAN_03683	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_03684	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_03686	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IFMEFEAN_03687	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
IFMEFEAN_03689	8.73e-09	yuzC	-	-	-	-	-	-	-
IFMEFEAN_03690	6.88e-297	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IFMEFEAN_03691	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IFMEFEAN_03692	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IFMEFEAN_03693	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IFMEFEAN_03694	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
IFMEFEAN_03695	6.9e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IFMEFEAN_03696	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
IFMEFEAN_03697	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
IFMEFEAN_03698	1.19e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IFMEFEAN_03699	3.85e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IFMEFEAN_03700	6.83e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_03701	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IFMEFEAN_03702	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IFMEFEAN_03703	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IFMEFEAN_03704	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IFMEFEAN_03705	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IFMEFEAN_03706	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IFMEFEAN_03707	2.96e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
IFMEFEAN_03708	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IFMEFEAN_03709	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IFMEFEAN_03710	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IFMEFEAN_03711	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_03712	2.59e-227	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IFMEFEAN_03713	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IFMEFEAN_03714	5.78e-288	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IFMEFEAN_03715	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03716	1.27e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IFMEFEAN_03717	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IFMEFEAN_03718	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IFMEFEAN_03719	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IFMEFEAN_03720	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IFMEFEAN_03721	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IFMEFEAN_03722	2.69e-148	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03723	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
IFMEFEAN_03724	1.39e-299	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IFMEFEAN_03725	1.92e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IFMEFEAN_03727	5.26e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFMEFEAN_03728	1.36e-123	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
IFMEFEAN_03729	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IFMEFEAN_03730	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IFMEFEAN_03731	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IFMEFEAN_03732	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IFMEFEAN_03733	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
IFMEFEAN_03734	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IFMEFEAN_03735	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IFMEFEAN_03736	2.92e-88	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IFMEFEAN_03737	7.68e-25	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IFMEFEAN_03738	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IFMEFEAN_03739	1.94e-95	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
IFMEFEAN_03740	2.04e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
IFMEFEAN_03741	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IFMEFEAN_03742	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_03745	1.55e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IFMEFEAN_03748	9.15e-54	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IFMEFEAN_03749	4.72e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IFMEFEAN_03750	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IFMEFEAN_03751	9.7e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IFMEFEAN_03752	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IFMEFEAN_03753	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IFMEFEAN_03754	1.75e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IFMEFEAN_03755	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IFMEFEAN_03756	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
IFMEFEAN_03757	1.53e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IFMEFEAN_03758	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IFMEFEAN_03759	3.78e-88	ylbD	-	-	S	-	-	-	Putative coat protein
IFMEFEAN_03760	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IFMEFEAN_03761	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IFMEFEAN_03762	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
IFMEFEAN_03763	1.43e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IFMEFEAN_03764	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IFMEFEAN_03765	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IFMEFEAN_03766	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IFMEFEAN_03767	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IFMEFEAN_03768	1.67e-291	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IFMEFEAN_03770	1.15e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IFMEFEAN_03771	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IFMEFEAN_03772	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IFMEFEAN_03773	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IFMEFEAN_03774	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IFMEFEAN_03775	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IFMEFEAN_03776	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IFMEFEAN_03777	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IFMEFEAN_03778	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
IFMEFEAN_03779	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IFMEFEAN_03780	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IFMEFEAN_03781	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IFMEFEAN_03782	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IFMEFEAN_03783	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IFMEFEAN_03784	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IFMEFEAN_03785	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IFMEFEAN_03786	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IFMEFEAN_03787	2.77e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IFMEFEAN_03788	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03789	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03790	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
IFMEFEAN_03791	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IFMEFEAN_03792	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IFMEFEAN_03793	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IFMEFEAN_03795	3.49e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IFMEFEAN_03796	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_03797	6.57e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IFMEFEAN_03798	6.37e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IFMEFEAN_03799	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IFMEFEAN_03800	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
IFMEFEAN_03801	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IFMEFEAN_03802	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IFMEFEAN_03803	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IFMEFEAN_03804	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IFMEFEAN_03805	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IFMEFEAN_03806	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IFMEFEAN_03807	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IFMEFEAN_03808	2.63e-11	-	-	-	-	-	-	-	-
IFMEFEAN_03809	1e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
IFMEFEAN_03810	1.6e-276	-	-	-	S	-	-	-	Phage Terminase
IFMEFEAN_03811	2.58e-14	-	-	-	-	-	-	-	-
IFMEFEAN_03812	4.77e-273	-	-	-	S	-	-	-	Phage portal protein
IFMEFEAN_03813	9.36e-135	-	-	-	S	-	-	-	peptidase activity
IFMEFEAN_03814	3.43e-227	-	-	-	S	-	-	-	capsid protein
IFMEFEAN_03815	8.02e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
IFMEFEAN_03816	1.23e-39	-	-	-	S	-	-	-	peptidoglycan catabolic process
IFMEFEAN_03817	1.23e-32	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IFMEFEAN_03818	1.54e-62	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IFMEFEAN_03819	1.42e-40	-	-	-	-	-	-	-	-
IFMEFEAN_03820	9.75e-79	-	-	-	-	-	-	-	-
IFMEFEAN_03821	1.58e-36	-	-	-	-	-	-	-	-
IFMEFEAN_03822	4.09e-16	-	-	-	-	-	-	-	-
IFMEFEAN_03823	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
IFMEFEAN_03824	1.96e-141	-	-	-	S	-	-	-	Phage tail protein
IFMEFEAN_03825	1.62e-307	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IFMEFEAN_03826	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IFMEFEAN_03827	1.82e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IFMEFEAN_03828	4.98e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IFMEFEAN_03829	1.16e-301	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IFMEFEAN_03831	4.47e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IFMEFEAN_03832	4.16e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IFMEFEAN_03833	1.33e-174	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IFMEFEAN_03834	2.91e-297	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IFMEFEAN_03835	2.99e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IFMEFEAN_03837	4.26e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_03840	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IFMEFEAN_03843	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_03844	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IFMEFEAN_03845	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IFMEFEAN_03846	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_03847	1.24e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_03848	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IFMEFEAN_03849	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IFMEFEAN_03850	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IFMEFEAN_03851	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
IFMEFEAN_03852	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IFMEFEAN_03853	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
IFMEFEAN_03854	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IFMEFEAN_03855	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IFMEFEAN_03856	6.92e-92	yviE	-	-	-	-	-	-	-
IFMEFEAN_03857	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IFMEFEAN_03858	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IFMEFEAN_03859	4.34e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IFMEFEAN_03860	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
IFMEFEAN_03861	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IFMEFEAN_03862	6.02e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IFMEFEAN_03863	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IFMEFEAN_03864	2.46e-67	-	-	-	-	-	-	-	-
IFMEFEAN_03865	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IFMEFEAN_03866	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IFMEFEAN_03867	1.08e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_03868	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IFMEFEAN_03871	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
IFMEFEAN_03874	2.43e-14	-	-	-	-	-	-	-	-
IFMEFEAN_03875	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
IFMEFEAN_03877	3.72e-202	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IFMEFEAN_03878	3.74e-37	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IFMEFEAN_03879	4.28e-149	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IFMEFEAN_03880	1.18e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IFMEFEAN_03881	6.15e-259	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IFMEFEAN_03882	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IFMEFEAN_03883	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IFMEFEAN_03884	6.04e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IFMEFEAN_03885	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IFMEFEAN_03886	3.23e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IFMEFEAN_03887	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IFMEFEAN_03888	5.98e-100	-	-	-	K	-	-	-	acetyltransferase
IFMEFEAN_03889	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMEFEAN_03890	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
IFMEFEAN_03891	7.65e-83	yhfM	-	-	-	-	-	-	-
IFMEFEAN_03892	2.06e-85	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IFMEFEAN_03893	1.25e-56	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMEFEAN_03894	2.51e-13	-	-	-	-	-	-	-	-
IFMEFEAN_03896	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IFMEFEAN_03897	4.02e-109	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IFMEFEAN_03898	8.72e-142	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IFMEFEAN_03899	1.79e-74	-	-	-	S	-	-	-	Bacteriophage holin family
IFMEFEAN_03902	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IFMEFEAN_03903	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IFMEFEAN_03904	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IFMEFEAN_03906	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IFMEFEAN_03907	7.54e-22	-	-	-	-	-	-	-	-
IFMEFEAN_03910	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IFMEFEAN_03912	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
IFMEFEAN_03915	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
IFMEFEAN_03916	8.92e-96	-	-	-	-	-	-	-	-
IFMEFEAN_03917	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IFMEFEAN_03920	9.36e-65	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IFMEFEAN_03921	1.82e-181	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IFMEFEAN_03922	5.45e-112	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IFMEFEAN_03923	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
IFMEFEAN_03924	2.87e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IFMEFEAN_03925	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IFMEFEAN_03928	6.31e-173	yndL	-	-	S	-	-	-	Replication protein
IFMEFEAN_03929	3.11e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IFMEFEAN_03930	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IFMEFEAN_03931	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IFMEFEAN_03932	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IFMEFEAN_03933	5.4e-143	yneB	-	-	L	-	-	-	resolvase
IFMEFEAN_03934	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IFMEFEAN_03935	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IFMEFEAN_03936	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IFMEFEAN_03937	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IFMEFEAN_03938	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IFMEFEAN_03939	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IFMEFEAN_03940	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IFMEFEAN_03941	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IFMEFEAN_03942	2.54e-53	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IFMEFEAN_03948	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
IFMEFEAN_03949	1.55e-140	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_03950	3.75e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_03952	1.15e-20	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IFMEFEAN_03953	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IFMEFEAN_03954	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
IFMEFEAN_03955	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
IFMEFEAN_03956	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_03957	9.99e-197	-	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_03958	8.66e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
IFMEFEAN_03959	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IFMEFEAN_03960	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IFMEFEAN_03961	9.32e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IFMEFEAN_03962	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IFMEFEAN_03963	1.37e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IFMEFEAN_03964	2.49e-95	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IFMEFEAN_03965	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_03966	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
IFMEFEAN_03967	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IFMEFEAN_03968	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IFMEFEAN_03969	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
IFMEFEAN_03970	4.95e-140	-	-	-	-	-	-	-	-
IFMEFEAN_03971	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IFMEFEAN_03973	1.15e-58	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IFMEFEAN_03974	3.66e-78	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IFMEFEAN_03975	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IFMEFEAN_03976	3.56e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IFMEFEAN_03977	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IFMEFEAN_03978	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IFMEFEAN_03979	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IFMEFEAN_03980	7.44e-159	yodN	-	-	-	-	-	-	-
IFMEFEAN_03982	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
IFMEFEAN_03983	5.26e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IFMEFEAN_03984	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
IFMEFEAN_03985	2.08e-12	-	-	-	-	-	-	-	-
IFMEFEAN_03986	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IFMEFEAN_03987	7.71e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IFMEFEAN_03988	2.81e-40	yodI	-	-	-	-	-	-	-
IFMEFEAN_03989	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
IFMEFEAN_03990	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IFMEFEAN_03991	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IFMEFEAN_03992	3.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IFMEFEAN_03993	5.61e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IFMEFEAN_03994	2.17e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IFMEFEAN_03995	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
IFMEFEAN_03996	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
IFMEFEAN_03997	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
IFMEFEAN_03998	3.6e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IFMEFEAN_03999	1.13e-13	-	-	-	-	-	-	-	-
IFMEFEAN_04000	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IFMEFEAN_04001	6.68e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IFMEFEAN_04002	1.85e-58	-	-	-	-	-	-	-	-
IFMEFEAN_04003	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IFMEFEAN_04004	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IFMEFEAN_04005	2.91e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IFMEFEAN_04006	2.93e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IFMEFEAN_04008	2.14e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IFMEFEAN_04009	3.12e-291	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IFMEFEAN_04010	2.48e-262	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IFMEFEAN_04011	4.94e-140	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IFMEFEAN_04012	7.38e-205	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IFMEFEAN_04013	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IFMEFEAN_04014	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IFMEFEAN_04015	1.05e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IFMEFEAN_04018	9.18e-172	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IFMEFEAN_04019	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IFMEFEAN_04020	1.24e-76	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IFMEFEAN_04021	1.07e-09	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IFMEFEAN_04022	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
IFMEFEAN_04023	2.22e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IFMEFEAN_04024	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IFMEFEAN_04025	1.2e-114	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMEFEAN_04026	1.22e-173	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMEFEAN_04027	2.31e-41	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_04028	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_04029	3.64e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IFMEFEAN_04030	5.93e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IFMEFEAN_04031	5.22e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IFMEFEAN_04032	2.78e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_04034	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IFMEFEAN_04035	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IFMEFEAN_04036	4.28e-163	-	-	-	-	-	-	-	-
IFMEFEAN_04043	5.89e-58	-	-	-	L	-	-	-	Phage integrase family
IFMEFEAN_04044	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IFMEFEAN_04049	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IFMEFEAN_04050	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IFMEFEAN_04051	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IFMEFEAN_04052	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IFMEFEAN_04053	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IFMEFEAN_04054	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IFMEFEAN_04055	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_04056	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
IFMEFEAN_04057	2.25e-59	ybfN	-	-	-	-	-	-	-
IFMEFEAN_04058	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IFMEFEAN_04059	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IFMEFEAN_04060	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IFMEFEAN_04061	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IFMEFEAN_04063	3.97e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IFMEFEAN_04064	1.54e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IFMEFEAN_04065	2.61e-73	-	-	-	-	-	-	-	-
IFMEFEAN_04066	1.93e-122	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
IFMEFEAN_04067	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
IFMEFEAN_04068	3.63e-43	-	-	-	K	-	-	-	sigma factor activity
IFMEFEAN_04069	2.88e-185	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
IFMEFEAN_04070	5.01e-133	ybfH	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_04071	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IFMEFEAN_04074	6.21e-57	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_04075	5.4e-184	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_04076	8.65e-202	ybfA	-	-	K	-	-	-	FR47-like protein
IFMEFEAN_04077	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IFMEFEAN_04078	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IFMEFEAN_04079	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IFMEFEAN_04080	0.0	ybeC	-	-	E	-	-	-	amino acid
IFMEFEAN_04081	1.28e-37	ybyB	-	-	-	-	-	-	-
IFMEFEAN_04082	2.99e-311	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IFMEFEAN_04083	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IFMEFEAN_04084	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
IFMEFEAN_04085	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IFMEFEAN_04086	4.72e-134	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IFMEFEAN_04087	1.34e-196	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IFMEFEAN_04088	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFMEFEAN_04089	6.37e-103	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IFMEFEAN_04090	8.94e-90	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IFMEFEAN_04091	2.27e-220	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IFMEFEAN_04092	2.44e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
IFMEFEAN_04093	1.8e-177	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IFMEFEAN_04094	1.47e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IFMEFEAN_04095	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IFMEFEAN_04096	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IFMEFEAN_04097	5.68e-314	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IFMEFEAN_04098	3e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IFMEFEAN_04099	5.39e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IFMEFEAN_04100	1.28e-201	ywbI	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_04101	4.47e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IFMEFEAN_04102	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IFMEFEAN_04103	7.14e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
IFMEFEAN_04104	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IFMEFEAN_04105	1.28e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IFMEFEAN_04106	8.1e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IFMEFEAN_04107	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IFMEFEAN_04108	1.81e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFMEFEAN_04109	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IFMEFEAN_04110	4.43e-307	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_04111	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IFMEFEAN_04112	5.37e-216	gspA	-	-	M	-	-	-	General stress
IFMEFEAN_04113	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
IFMEFEAN_04114	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_04115	1.28e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFMEFEAN_04116	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IFMEFEAN_04117	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
IFMEFEAN_04118	3.2e-265	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IFMEFEAN_04119	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IFMEFEAN_04120	6.01e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IFMEFEAN_04121	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_04122	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IFMEFEAN_04123	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IFMEFEAN_04124	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IFMEFEAN_04125	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IFMEFEAN_04126	1.63e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IFMEFEAN_04127	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IFMEFEAN_04128	2.71e-176	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_04129	5.75e-160	-	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IFMEFEAN_04130	1.26e-18	-	-	-	-	-	-	-	-
IFMEFEAN_04132	3.05e-20	-	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IFMEFEAN_04134	2.94e-17	-	-	-	EGP	-	-	-	Major Facilitator
IFMEFEAN_04135	6.4e-09	-	-	-	J	-	-	-	O-methyltransferase
IFMEFEAN_04136	3.54e-95	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC superfamily ATP binding cassette transporter ABC protein
IFMEFEAN_04137	2.98e-14	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IFMEFEAN_04139	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IFMEFEAN_04140	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
IFMEFEAN_04141	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IFMEFEAN_04142	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IFMEFEAN_04143	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IFMEFEAN_04144	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IFMEFEAN_04145	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
IFMEFEAN_04146	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IFMEFEAN_04147	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IFMEFEAN_04148	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
IFMEFEAN_04149	2.23e-54	-	-	-	-	-	-	-	-
IFMEFEAN_04150	8.15e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IFMEFEAN_04151	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
IFMEFEAN_04152	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IFMEFEAN_04153	3.15e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IFMEFEAN_04154	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IFMEFEAN_04155	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IFMEFEAN_04156	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IFMEFEAN_04157	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IFMEFEAN_04158	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IFMEFEAN_04159	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
IFMEFEAN_04160	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IFMEFEAN_04161	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IFMEFEAN_04162	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IFMEFEAN_04163	1.96e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IFMEFEAN_04164	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IFMEFEAN_04165	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IFMEFEAN_04166	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IFMEFEAN_04167	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IFMEFEAN_04168	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IFMEFEAN_04169	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IFMEFEAN_04170	1.79e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IFMEFEAN_04174	7.24e-60	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_04175	1.7e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IFMEFEAN_04176	4.59e-23	-	-	-	-	-	-	-	-
IFMEFEAN_04178	2.79e-87	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
IFMEFEAN_04179	2.01e-64	-	-	-	L	ko:K02315,ko:K11144	-	ko00000,ko03032	DNA replication protein
IFMEFEAN_04181	1.88e-09	-	-	-	-	-	-	-	-
IFMEFEAN_04182	3.29e-104	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IFMEFEAN_04183	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IFMEFEAN_04187	9.33e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
IFMEFEAN_04188	1.96e-302	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFMEFEAN_04189	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IFMEFEAN_04190	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IFMEFEAN_04191	4.92e-285	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IFMEFEAN_04192	1.48e-122	-	-	-	S	-	-	-	YcxB-like protein
IFMEFEAN_04193	1.17e-198	ycxC	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_04194	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
IFMEFEAN_04195	8.24e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IFMEFEAN_04196	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IFMEFEAN_04197	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IFMEFEAN_04198	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IFMEFEAN_04199	4.3e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IFMEFEAN_04200	1.25e-207	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IFMEFEAN_04201	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IFMEFEAN_04202	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IFMEFEAN_04203	4.02e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IFMEFEAN_04204	6.45e-55	yclD	-	-	-	-	-	-	-
IFMEFEAN_04205	6.42e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
IFMEFEAN_04206	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IFMEFEAN_04207	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IFMEFEAN_04208	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IFMEFEAN_04209	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
IFMEFEAN_04211	1.98e-157	ywcC	-	-	K	-	-	-	transcriptional regulator
IFMEFEAN_04212	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
IFMEFEAN_04213	5.34e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IFMEFEAN_04214	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IFMEFEAN_04215	5.11e-49	ydaS	-	-	S	-	-	-	membrane
IFMEFEAN_04216	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IFMEFEAN_04217	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IFMEFEAN_04218	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IFMEFEAN_04219	1.3e-82	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IFMEFEAN_04220	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IFMEFEAN_04222	2.97e-159	-	-	-	L	-	-	-	TIGRFAM Transposase, IS605 OrfB, C-terminal
IFMEFEAN_04223	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IFMEFEAN_04224	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IFMEFEAN_04225	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IFMEFEAN_04226	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IFMEFEAN_04227	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IFMEFEAN_04228	1.91e-42	yozC	-	-	-	-	-	-	-
IFMEFEAN_04229	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
IFMEFEAN_04230	1.83e-49	yocN	-	-	-	-	-	-	-
IFMEFEAN_04231	2.94e-55	yozN	-	-	-	-	-	-	-
IFMEFEAN_04232	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IFMEFEAN_04233	3.93e-41	-	-	-	-	-	-	-	-
IFMEFEAN_04234	4.29e-70	yocL	-	-	-	-	-	-	-
IFMEFEAN_04235	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
IFMEFEAN_04236	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IFMEFEAN_04237	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IFMEFEAN_04238	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IFMEFEAN_04240	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFMEFEAN_04241	4.09e-251	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_04242	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IFMEFEAN_04243	1.41e-242	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IFMEFEAN_04244	7.04e-118	yocC	-	-	-	-	-	-	-
IFMEFEAN_04245	8.69e-184	-	-	-	-	-	-	-	-
IFMEFEAN_04246	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IFMEFEAN_04249	4.26e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IFMEFEAN_04250	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IFMEFEAN_04251	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IFMEFEAN_04252	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IFMEFEAN_04253	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IFMEFEAN_04254	1.29e-236	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IFMEFEAN_04255	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IFMEFEAN_04256	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
IFMEFEAN_04257	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IFMEFEAN_04258	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_04259	4.29e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IFMEFEAN_04260	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IFMEFEAN_04262	1.25e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IFMEFEAN_04263	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IFMEFEAN_04264	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IFMEFEAN_04265	2.77e-37	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IFMEFEAN_04266	2.97e-270	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IFMEFEAN_04267	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IFMEFEAN_04268	5.88e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IFMEFEAN_04269	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IFMEFEAN_04270	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
IFMEFEAN_04271	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IFMEFEAN_04272	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IFMEFEAN_04273	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IFMEFEAN_04274	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IFMEFEAN_04275	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IFMEFEAN_04276	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IFMEFEAN_04277	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IFMEFEAN_04278	2.85e-215	eamA1	-	-	EG	-	-	-	spore germination
IFMEFEAN_04279	4.8e-149	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFMEFEAN_04280	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IFMEFEAN_04281	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IFMEFEAN_04282	1.5e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
IFMEFEAN_04283	1.58e-36	-	-	-	-	-	-	-	-
IFMEFEAN_04284	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IFMEFEAN_04285	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IFMEFEAN_04287	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IFMEFEAN_04288	2.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IFMEFEAN_04289	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IFMEFEAN_04290	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IFMEFEAN_04291	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IFMEFEAN_04292	1.41e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IFMEFEAN_04293	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IFMEFEAN_04294	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IFMEFEAN_04295	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
IFMEFEAN_04296	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IFMEFEAN_04297	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IFMEFEAN_04298	1.74e-57	ylaE	-	-	-	-	-	-	-
IFMEFEAN_04300	1.79e-56	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IFMEFEAN_04301	1.44e-56	ylaB	-	-	-	-	-	-	-
IFMEFEAN_04302	0.0	ylaA	-	-	-	-	-	-	-
IFMEFEAN_04303	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IFMEFEAN_04304	1.01e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IFMEFEAN_04305	1.17e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IFMEFEAN_04306	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IFMEFEAN_04307	4.48e-35	ykzI	-	-	-	-	-	-	-
IFMEFEAN_04308	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IFMEFEAN_04309	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IFMEFEAN_04310	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IFMEFEAN_04312	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IFMEFEAN_04313	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IFMEFEAN_04314	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IFMEFEAN_04315	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IFMEFEAN_04316	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IFMEFEAN_04317	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IFMEFEAN_04318	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IFMEFEAN_04319	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IFMEFEAN_04320	8.28e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IFMEFEAN_04321	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IFMEFEAN_04322	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFMEFEAN_04323	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IFMEFEAN_04324	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IFMEFEAN_04325	8.84e-206	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IFMEFEAN_04326	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IFMEFEAN_04327	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IFMEFEAN_04328	8.77e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IFMEFEAN_04329	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IFMEFEAN_04330	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IFMEFEAN_04331	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IFMEFEAN_04332	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IFMEFEAN_04333	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IFMEFEAN_04334	4.12e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IFMEFEAN_04335	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IFMEFEAN_04336	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IFMEFEAN_04338	3.17e-170	-	-	-	L	-	-	-	Phage integrase family
IFMEFEAN_04341	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IFMEFEAN_04342	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
IFMEFEAN_04343	6.97e-98	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IFMEFEAN_04344	3.84e-87	res	-	-	L	-	-	-	Resolvase, N terminal domain
IFMEFEAN_04345	2.61e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IFMEFEAN_04346	8.3e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IFMEFEAN_04348	3.24e-93	-	-	-	S	-	-	-	CAAX protease self-immunity
IFMEFEAN_04349	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IFMEFEAN_04350	8.64e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IFMEFEAN_04351	1.6e-08	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IFMEFEAN_04352	1.9e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IFMEFEAN_04353	4.19e-20	ynaF	-	-	-	-	-	-	-
IFMEFEAN_04355	2.81e-106	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IFMEFEAN_04356	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IFMEFEAN_04357	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IFMEFEAN_04358	6.82e-273	xylR	-	-	GK	-	-	-	ROK family
IFMEFEAN_04359	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IFMEFEAN_04360	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IFMEFEAN_04361	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IFMEFEAN_04362	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IFMEFEAN_04363	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IFMEFEAN_04364	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IFMEFEAN_04365	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IFMEFEAN_04366	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IFMEFEAN_04367	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFMEFEAN_04369	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IFMEFEAN_04370	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IFMEFEAN_04371	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IFMEFEAN_04372	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IFMEFEAN_04373	5.45e-296	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IFMEFEAN_04374	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IFMEFEAN_04375	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IFMEFEAN_04376	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IFMEFEAN_04377	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IFMEFEAN_04378	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMEFEAN_04379	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMEFEAN_04380	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFMEFEAN_04381	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IFMEFEAN_04382	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IFMEFEAN_04383	2.69e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IFMEFEAN_04384	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IFMEFEAN_04385	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
IFMEFEAN_04386	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
IFMEFEAN_04388	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
IFMEFEAN_04389	2.82e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IFMEFEAN_04391	4.01e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IFMEFEAN_04392	4.98e-106	yoaW	-	-	-	-	-	-	-
IFMEFEAN_04393	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IFMEFEAN_04394	7.66e-99	-	-	-	-	-	-	-	-
IFMEFEAN_04395	3.2e-59	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IFMEFEAN_04396	4.46e-23	-	-	-	-	-	-	-	-
IFMEFEAN_04398	1.57e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_04400	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IFMEFEAN_04401	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
IFMEFEAN_04402	1.08e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
IFMEFEAN_04403	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
IFMEFEAN_04410	1.76e-59	-	-	-	S	-	-	-	dUTPase
IFMEFEAN_04412	1.12e-07	-	-	-	S	-	-	-	YopX protein
IFMEFEAN_04414	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IFMEFEAN_04415	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IFMEFEAN_04416	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IFMEFEAN_04417	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IFMEFEAN_04418	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IFMEFEAN_04419	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IFMEFEAN_04420	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
IFMEFEAN_04422	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IFMEFEAN_04423	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IFMEFEAN_04424	3.3e-71	yneQ	-	-	-	-	-	-	-
IFMEFEAN_04425	6.98e-279	-	-	-	L	-	-	-	Transposase
IFMEFEAN_04426	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
IFMEFEAN_04427	1.75e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
IFMEFEAN_04428	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
IFMEFEAN_04429	9.58e-67	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IFMEFEAN_04430	1.6e-94	-	-	-	L	-	-	-	Phage integrase family
IFMEFEAN_04431	9.46e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
IFMEFEAN_04432	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IFMEFEAN_04433	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IFMEFEAN_04434	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IFMEFEAN_04435	8.11e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IFMEFEAN_04436	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IFMEFEAN_04437	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IFMEFEAN_04438	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IFMEFEAN_04439	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IFMEFEAN_04440	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
IFMEFEAN_04441	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IFMEFEAN_04442	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IFMEFEAN_04443	5.51e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IFMEFEAN_04444	1.75e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IFMEFEAN_04445	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IFMEFEAN_04446	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IFMEFEAN_04447	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IFMEFEAN_04448	5.43e-52	ykoA	-	-	-	-	-	-	-
IFMEFEAN_04449	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IFMEFEAN_04450	1.93e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IFMEFEAN_04451	1.02e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IFMEFEAN_04452	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
IFMEFEAN_04453	3.17e-212	yrdR	-	-	EG	-	-	-	EamA-like transporter family
IFMEFEAN_04454	1.4e-203	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_04455	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
IFMEFEAN_04456	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IFMEFEAN_04457	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFMEFEAN_04458	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IFMEFEAN_04459	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IFMEFEAN_04460	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IFMEFEAN_04463	0.0	-	-	-	V	-	-	-	Beta-lactamase
IFMEFEAN_04465	3.11e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IFMEFEAN_04467	4.82e-69	ynaF	-	-	-	-	-	-	-
IFMEFEAN_04468	2.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IFMEFEAN_04469	1.33e-160	ynaC	-	-	-	-	-	-	-
IFMEFEAN_04470	8.25e-61	-	-	-	S	-	-	-	Restriction endonuclease
IFMEFEAN_04471	7.12e-37	-	-	-	-	-	-	-	-
IFMEFEAN_04472	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
IFMEFEAN_04473	3.5e-35	-	-	-	K	-	-	-	Helix-turn-helix domain
IFMEFEAN_04474	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
IFMEFEAN_04475	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IFMEFEAN_04476	1.87e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IFMEFEAN_04477	2.29e-29	ywtC	-	-	-	-	-	-	-
IFMEFEAN_04478	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IFMEFEAN_04479	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IFMEFEAN_04480	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IFMEFEAN_04487	1.12e-33	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_04488	1.08e-60	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IFMEFEAN_04489	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IFMEFEAN_04490	2.43e-58	yjcN	-	-	-	-	-	-	-
IFMEFEAN_04491	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IFMEFEAN_04492	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IFMEFEAN_04493	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IFMEFEAN_04498	3.09e-63	-	-	-	S	-	-	-	dUTPase
IFMEFEAN_04513	0.000711	-	-	-	-	-	-	-	-
IFMEFEAN_04516	6.53e-108	yuaE	-	-	S	-	-	-	DinB superfamily
IFMEFEAN_04517	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IFMEFEAN_04518	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IFMEFEAN_04519	5.71e-121	-	-	-	M	-	-	-	FR47-like protein
IFMEFEAN_04520	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IFMEFEAN_04543	1.86e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
IFMEFEAN_04544	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IFMEFEAN_04545	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IFMEFEAN_04546	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
IFMEFEAN_04547	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
IFMEFEAN_04549	3.86e-10	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
IFMEFEAN_04551	8.21e-15	-	-	-	K	-	-	-	Transcriptional regulator
IFMEFEAN_04552	2e-169	-	-	-	-	-	-	-	-
IFMEFEAN_04554	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IFMEFEAN_04555	1.23e-242	-	-	-	I	-	-	-	Pfam Lipase (class 3)
IFMEFEAN_04556	9.96e-22	-	-	-	-	-	-	-	-
IFMEFEAN_04557	8.22e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IFMEFEAN_04559	3.86e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)