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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NEHPIGDC_00001	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_00002	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
NEHPIGDC_00003	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
NEHPIGDC_00004	2.65e-287	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEHPIGDC_00005	4.25e-122	-	-	-	S	-	-	-	YcxB-like protein
NEHPIGDC_00006	1.33e-204	ycxC	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_00007	7.76e-314	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
NEHPIGDC_00008	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
NEHPIGDC_00009	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
NEHPIGDC_00010	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NEHPIGDC_00011	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NEHPIGDC_00012	1.23e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NEHPIGDC_00013	8.83e-208	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
NEHPIGDC_00014	6.42e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NEHPIGDC_00015	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NEHPIGDC_00016	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
NEHPIGDC_00017	2.51e-108	yclD	-	-	-	-	-	-	-
NEHPIGDC_00018	7.82e-202	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
NEHPIGDC_00019	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
NEHPIGDC_00020	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
NEHPIGDC_00022	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
NEHPIGDC_00023	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
NEHPIGDC_00024	2.67e-253	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
NEHPIGDC_00025	4.82e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NEHPIGDC_00026	6.2e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
NEHPIGDC_00027	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_00028	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEHPIGDC_00029	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
NEHPIGDC_00031	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NEHPIGDC_00032	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NEHPIGDC_00033	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NEHPIGDC_00034	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_00035	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_00036	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00037	5.72e-213	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
NEHPIGDC_00038	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
NEHPIGDC_00039	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00040	2.48e-173	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NEHPIGDC_00041	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
NEHPIGDC_00042	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPIGDC_00043	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_00044	2.8e-312	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEHPIGDC_00045	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEHPIGDC_00046	3.37e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
NEHPIGDC_00047	3.82e-183	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_00048	3.99e-134	ycnI	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00049	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
NEHPIGDC_00050	7.07e-137	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NEHPIGDC_00051	3.16e-73	-	-	-	-	-	-	-	-
NEHPIGDC_00052	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
NEHPIGDC_00053	2.38e-94	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NEHPIGDC_00054	2.54e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
NEHPIGDC_00055	2.91e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
NEHPIGDC_00057	5.1e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEHPIGDC_00058	1.92e-140	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
NEHPIGDC_00059	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
NEHPIGDC_00061	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
NEHPIGDC_00062	5.43e-181	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
NEHPIGDC_00063	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
NEHPIGDC_00064	2.85e-189	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
NEHPIGDC_00065	5.04e-173	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
NEHPIGDC_00066	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
NEHPIGDC_00067	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00068	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
NEHPIGDC_00070	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
NEHPIGDC_00071	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
NEHPIGDC_00072	3.14e-178	ycsN	-	-	S	-	-	-	Oxidoreductase
NEHPIGDC_00073	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
NEHPIGDC_00074	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
NEHPIGDC_00075	5.81e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
NEHPIGDC_00076	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_00077	3.91e-125	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
NEHPIGDC_00078	1.33e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEHPIGDC_00079	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
NEHPIGDC_00080	4.39e-177	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NEHPIGDC_00081	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
NEHPIGDC_00082	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
NEHPIGDC_00083	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEHPIGDC_00084	4.03e-263	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NEHPIGDC_00085	1.56e-193	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
NEHPIGDC_00086	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
NEHPIGDC_00087	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
NEHPIGDC_00088	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
NEHPIGDC_00089	0.0	ydaO	-	-	E	-	-	-	amino acid
NEHPIGDC_00090	6.44e-30	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NEHPIGDC_00091	2.66e-36	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NEHPIGDC_00092	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
NEHPIGDC_00093	2.5e-52	-	-	-	-	-	-	-	-
NEHPIGDC_00094	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NEHPIGDC_00095	1.67e-42	ydaS	-	-	S	-	-	-	membrane
NEHPIGDC_00096	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NEHPIGDC_00097	1.44e-188	ydbA	-	-	P	-	-	-	EcsC protein family
NEHPIGDC_00098	3.3e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
NEHPIGDC_00099	3.09e-78	ydbB	-	-	G	-	-	-	Cupin domain
NEHPIGDC_00100	2.58e-82	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
NEHPIGDC_00101	2.24e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
NEHPIGDC_00102	4.28e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NEHPIGDC_00103	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NEHPIGDC_00104	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NEHPIGDC_00105	1.8e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHPIGDC_00106	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
NEHPIGDC_00107	2.09e-215	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00108	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEHPIGDC_00109	9.32e-70	ydbL	-	-	-	-	-	-	-
NEHPIGDC_00110	2.14e-279	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
NEHPIGDC_00111	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
NEHPIGDC_00113	9.08e-201	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHPIGDC_00114	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
NEHPIGDC_00115	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NEHPIGDC_00116	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEHPIGDC_00117	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEHPIGDC_00118	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NEHPIGDC_00119	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
NEHPIGDC_00120	3.46e-137	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
NEHPIGDC_00121	1.6e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEHPIGDC_00122	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
NEHPIGDC_00123	2.41e-280	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEHPIGDC_00124	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NEHPIGDC_00125	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NEHPIGDC_00126	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
NEHPIGDC_00127	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
NEHPIGDC_00128	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NEHPIGDC_00129	3.75e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
NEHPIGDC_00130	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
NEHPIGDC_00131	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NEHPIGDC_00132	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_00133	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
NEHPIGDC_00134	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
NEHPIGDC_00135	1.59e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NEHPIGDC_00146	1.55e-188	-	-	-	KLT	-	-	-	Protein kinase domain
NEHPIGDC_00151	9.8e-262	-	-	-	KLT	-	-	-	Protein kinase domain
NEHPIGDC_00152	1.93e-259	abcA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NEHPIGDC_00153	2.57e-62	ydeH	-	-	-	-	-	-	-
NEHPIGDC_00154	3.28e-11	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
NEHPIGDC_00155	9.03e-14	-	-	-	E	ko:K07032	-	ko00000	PFAM Glyoxalase bleomycin resistance protein dioxygenase
NEHPIGDC_00156	1.04e-44	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NEHPIGDC_00157	1.54e-55	-	-	-	-	-	-	-	-
NEHPIGDC_00158	4.56e-243	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
NEHPIGDC_00159	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
NEHPIGDC_00160	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
NEHPIGDC_00161	3.34e-178	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEHPIGDC_00162	1.65e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
NEHPIGDC_00163	6.51e-220	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEHPIGDC_00164	2.45e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
NEHPIGDC_00165	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_00166	1.54e-276	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
NEHPIGDC_00167	1.12e-70	ydeH	-	-	-	-	-	-	-
NEHPIGDC_00168	4.05e-135	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NEHPIGDC_00169	8.21e-139	-	-	-	-	-	-	-	-
NEHPIGDC_00170	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_00171	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NEHPIGDC_00172	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NEHPIGDC_00173	9.4e-197	ydeK	-	-	EG	-	-	-	-transporter
NEHPIGDC_00174	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_00175	3.03e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
NEHPIGDC_00176	2.88e-136	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NEHPIGDC_00177	3.03e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEHPIGDC_00178	3.96e-195	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NEHPIGDC_00179	1.69e-89	ydeP	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00180	6.98e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
NEHPIGDC_00181	9.71e-258	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
NEHPIGDC_00182	1.78e-134	ydeS	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00183	1.05e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
NEHPIGDC_00184	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NEHPIGDC_00185	9.4e-190	-	-	-	J	-	-	-	GNAT acetyltransferase
NEHPIGDC_00186	1.55e-200	-	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_00187	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_00188	2.34e-148	ydfE	-	-	S	-	-	-	Flavin reductase like domain
NEHPIGDC_00189	1.5e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPIGDC_00190	1.87e-102	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NEHPIGDC_00192	7.24e-247	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_00193	3.82e-141	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_00194	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
NEHPIGDC_00195	1.88e-223	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NEHPIGDC_00196	6.51e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
NEHPIGDC_00197	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NEHPIGDC_00198	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHPIGDC_00199	8.12e-144	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
NEHPIGDC_00200	4.51e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NEHPIGDC_00201	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
NEHPIGDC_00202	8.92e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
NEHPIGDC_00204	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NEHPIGDC_00205	5.33e-39	-	-	-	-	-	-	-	-
NEHPIGDC_00207	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEHPIGDC_00208	4.97e-157	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEHPIGDC_00209	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NEHPIGDC_00210	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NEHPIGDC_00211	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
NEHPIGDC_00212	1.77e-122	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEHPIGDC_00213	2.35e-69	-	-	-	S	-	-	-	DoxX-like family
NEHPIGDC_00214	2.69e-109	yycN	-	-	K	-	-	-	Acetyltransferase
NEHPIGDC_00215	2.79e-40	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
NEHPIGDC_00216	3.62e-168	idhA	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NEHPIGDC_00217	1.16e-151	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
NEHPIGDC_00218	6.82e-240	xylT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_00219	4.53e-132	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NEHPIGDC_00220	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
NEHPIGDC_00221	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_00222	5.09e-119	-	-	-	S	-	-	-	DinB family
NEHPIGDC_00223	1.19e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_00224	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
NEHPIGDC_00225	1.84e-146	ydgI	-	-	C	-	-	-	nitroreductase
NEHPIGDC_00226	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
NEHPIGDC_00227	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
NEHPIGDC_00228	1.02e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEHPIGDC_00229	5.24e-158	ydhC	-	-	K	-	-	-	FCD
NEHPIGDC_00230	4.24e-308	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
NEHPIGDC_00231	7.9e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NEHPIGDC_00232	5e-162	-	-	-	-	-	-	-	-
NEHPIGDC_00233	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NEHPIGDC_00234	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
NEHPIGDC_00236	2.11e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_00237	4e-233	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NEHPIGDC_00238	9.44e-129	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
NEHPIGDC_00239	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NEHPIGDC_00240	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00241	1.44e-68	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00242	1.87e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPIGDC_00243	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NEHPIGDC_00244	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
NEHPIGDC_00245	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
NEHPIGDC_00246	5.09e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NEHPIGDC_00247	2.75e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
NEHPIGDC_00248	4.02e-201	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
NEHPIGDC_00251	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHPIGDC_00252	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEHPIGDC_00253	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
NEHPIGDC_00254	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEHPIGDC_00255	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NEHPIGDC_00256	8.12e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEHPIGDC_00257	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEHPIGDC_00258	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEHPIGDC_00259	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHPIGDC_00260	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
NEHPIGDC_00261	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEHPIGDC_00262	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEHPIGDC_00263	2.9e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NEHPIGDC_00264	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NEHPIGDC_00265	1.13e-98	-	-	-	S	-	-	-	Bacterial PH domain
NEHPIGDC_00266	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
NEHPIGDC_00267	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NEHPIGDC_00268	4.53e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
NEHPIGDC_00269	1.08e-226	yyaD	-	-	S	-	-	-	Membrane
NEHPIGDC_00270	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00271	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHPIGDC_00272	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEHPIGDC_00273	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NEHPIGDC_00274	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEHPIGDC_00275	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEHPIGDC_00276	3.43e-186	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NEHPIGDC_00277	3.4e-227	ccpB	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00278	1.15e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_00279	7.68e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
NEHPIGDC_00280	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
NEHPIGDC_00281	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEHPIGDC_00282	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
NEHPIGDC_00283	4.67e-313	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_00284	4.99e-136	yyaP	-	-	H	-	-	-	RibD C-terminal domain
NEHPIGDC_00285	5.21e-86	-	-	-	S	-	-	-	YjbR
NEHPIGDC_00286	2.72e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
NEHPIGDC_00287	4.8e-121	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
NEHPIGDC_00288	8.79e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_00289	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
NEHPIGDC_00290	6.18e-164	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEHPIGDC_00291	3.49e-97	yybC	-	-	-	-	-	-	-
NEHPIGDC_00292	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_00293	2.64e-210	yybE	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00294	1.44e-275	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_00295	1.96e-158	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
NEHPIGDC_00296	2.49e-87	-	-	-	S	-	-	-	SnoaL-like domain
NEHPIGDC_00297	5.24e-186	-	-	-	-	-	-	-	-
NEHPIGDC_00298	4.38e-142	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
NEHPIGDC_00299	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_00301	3.19e-90	-	-	-	-	-	-	-	-
NEHPIGDC_00302	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
NEHPIGDC_00303	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00304	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
NEHPIGDC_00306	1.75e-203	yybS	-	-	S	-	-	-	membrane
NEHPIGDC_00307	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NEHPIGDC_00308	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NEHPIGDC_00309	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHPIGDC_00310	9.87e-282	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
NEHPIGDC_00311	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
NEHPIGDC_00313	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NEHPIGDC_00314	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NEHPIGDC_00315	1.4e-100	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_00316	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEHPIGDC_00321	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_00322	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_00323	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00324	2.83e-199	yycI	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00325	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NEHPIGDC_00326	4.48e-277	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEHPIGDC_00327	2.2e-42	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NEHPIGDC_00328	1.32e-97	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NEHPIGDC_00329	6.75e-122	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
NEHPIGDC_00330	1.53e-214	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NEHPIGDC_00331	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NEHPIGDC_00332	1.37e-292	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
NEHPIGDC_00333	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NEHPIGDC_00334	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
NEHPIGDC_00336	2.9e-237	-	-	-	S	-	-	-	aspartate phosphatase
NEHPIGDC_00337	3.55e-109	yycN	-	-	K	-	-	-	Acetyltransferase
NEHPIGDC_00338	4.81e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NEHPIGDC_00339	4.68e-261	yycP	-	-	-	-	-	-	-
NEHPIGDC_00340	2.16e-39	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
NEHPIGDC_00342	5.2e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NEHPIGDC_00343	1.11e-87	-	-	-	-	-	-	-	-
NEHPIGDC_00345	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEHPIGDC_00347	1.7e-104	-	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (Adenine-specific)
NEHPIGDC_00348	2.16e-270	-	-	-	S	-	-	-	Domain of unknown function DUF87
NEHPIGDC_00349	9.75e-167	-	-	-	S	-	-	-	NurA domain
NEHPIGDC_00350	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
NEHPIGDC_00351	6.41e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NEHPIGDC_00352	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
NEHPIGDC_00353	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
NEHPIGDC_00354	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEHPIGDC_00355	1.68e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NEHPIGDC_00356	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NEHPIGDC_00357	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
NEHPIGDC_00358	1.35e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NEHPIGDC_00359	4.72e-241	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
NEHPIGDC_00360	3.11e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
NEHPIGDC_00361	7.25e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
NEHPIGDC_00362	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_00363	3.03e-255	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_00364	3.91e-130	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
NEHPIGDC_00365	7.06e-249	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
NEHPIGDC_00366	9.22e-287	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NEHPIGDC_00367	4.7e-98	yxaI	-	-	S	-	-	-	membrane protein domain
NEHPIGDC_00368	1.43e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
NEHPIGDC_00369	7.49e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
NEHPIGDC_00370	1.8e-271	yxaM	-	-	U	-	-	-	MFS_1 like family
NEHPIGDC_00371	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NEHPIGDC_00372	8.99e-114	yxnB	-	-	-	-	-	-	-
NEHPIGDC_00373	3.65e-59	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
NEHPIGDC_00374	7.46e-177	yxbB	-	-	Q	-	-	-	Met-10+ like-protein
NEHPIGDC_00375	1.16e-239	-	-	-	S	-	-	-	A domain family that is part of the cupin metalloenzyme superfamily.
NEHPIGDC_00376	6.59e-111	yxbD	3.2.2.20	-	K	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Acetyltransferase (GNAT) domain
NEHPIGDC_00377	7.19e-315	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NEHPIGDC_00378	3.23e-251	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEHPIGDC_00379	4.15e-193	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_00381	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
NEHPIGDC_00382	3.41e-312	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_00383	8.67e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
NEHPIGDC_00385	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NEHPIGDC_00386	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NEHPIGDC_00387	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEHPIGDC_00388	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NEHPIGDC_00389	5e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NEHPIGDC_00390	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NEHPIGDC_00391	1.23e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NEHPIGDC_00392	2.32e-295	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
NEHPIGDC_00393	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NEHPIGDC_00394	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
NEHPIGDC_00395	6.29e-186	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NEHPIGDC_00396	8.12e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NEHPIGDC_00397	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_00398	2.7e-231	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_00399	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00400	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NEHPIGDC_00401	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NEHPIGDC_00402	9.01e-228	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEHPIGDC_00403	6.79e-91	-	-	-	-	-	-	-	-
NEHPIGDC_00404	7.57e-28	yxeD	-	-	-	-	-	-	-
NEHPIGDC_00405	7.32e-42	yxeE	-	-	-	-	-	-	-
NEHPIGDC_00408	2.71e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
NEHPIGDC_00409	2.14e-234	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
NEHPIGDC_00410	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_00411	2.99e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_00412	2.49e-185	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NEHPIGDC_00413	5.18e-149	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NEHPIGDC_00414	1.13e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00415	8.27e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
NEHPIGDC_00416	1.21e-315	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
NEHPIGDC_00417	1.39e-258	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
NEHPIGDC_00418	9.11e-198	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
NEHPIGDC_00419	1.22e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NEHPIGDC_00420	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEHPIGDC_00421	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEHPIGDC_00422	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
NEHPIGDC_00423	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NEHPIGDC_00424	5.66e-230	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NEHPIGDC_00425	8.72e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
NEHPIGDC_00426	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NEHPIGDC_00427	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
NEHPIGDC_00428	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NEHPIGDC_00429	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
NEHPIGDC_00430	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
NEHPIGDC_00431	9.37e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
NEHPIGDC_00432	1.1e-277	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
NEHPIGDC_00433	9.35e-74	-	-	-	-	-	-	-	-
NEHPIGDC_00434	6.29e-54	-	-	-	-	-	-	-	-
NEHPIGDC_00435	5.65e-35	-	-	-	-	-	-	-	-
NEHPIGDC_00436	1.39e-79	-	-	-	-	-	-	-	-
NEHPIGDC_00437	3.23e-53	-	-	-	-	-	-	-	-
NEHPIGDC_00438	2.54e-13	-	-	-	-	-	-	-	-
NEHPIGDC_00439	1.07e-36	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2247)
NEHPIGDC_00440	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00441	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NEHPIGDC_00442	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
NEHPIGDC_00443	2.74e-158	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
NEHPIGDC_00444	2.98e-164	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_00445	4.88e-209	yxxF	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_00446	6.34e-54	-	-	-	-	-	-	-	-
NEHPIGDC_00447	1.4e-95	yxiG	-	-	-	-	-	-	-
NEHPIGDC_00448	3.07e-63	yxxG	-	-	-	-	-	-	-
NEHPIGDC_00450	6.46e-178	-	-	-	-	-	-	-	-
NEHPIGDC_00451	2.28e-117	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
NEHPIGDC_00452	9.17e-44	-	-	-	-	-	-	-	-
NEHPIGDC_00455	6.23e-62	yxiJ	-	-	S	-	-	-	YxiJ-like protein
NEHPIGDC_00458	1.54e-268	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEHPIGDC_00459	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NEHPIGDC_00460	3.12e-291	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
NEHPIGDC_00461	5.09e-141	-	-	-	-	-	-	-	-
NEHPIGDC_00462	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NEHPIGDC_00463	3.06e-184	bglS	-	-	M	-	-	-	licheninase activity
NEHPIGDC_00464	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NEHPIGDC_00465	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NEHPIGDC_00466	2.28e-63	yxiS	-	-	-	-	-	-	-
NEHPIGDC_00467	3.6e-134	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
NEHPIGDC_00468	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEHPIGDC_00469	1.15e-199	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
NEHPIGDC_00470	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
NEHPIGDC_00471	1.56e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NEHPIGDC_00472	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NEHPIGDC_00473	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NEHPIGDC_00474	3.81e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NEHPIGDC_00475	1.75e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NEHPIGDC_00476	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
NEHPIGDC_00479	7.76e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NEHPIGDC_00480	2.21e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
NEHPIGDC_00481	1.31e-256	-	-	-	T	-	-	-	Signal transduction histidine kinase
NEHPIGDC_00482	1.89e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
NEHPIGDC_00483	3e-249	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NEHPIGDC_00484	1.58e-181	-	-	-	-	-	-	-	-
NEHPIGDC_00485	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHPIGDC_00486	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEHPIGDC_00487	9.16e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NEHPIGDC_00488	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_00489	2.93e-196	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
NEHPIGDC_00491	0.0	-	-	-	O	-	-	-	Peptidase family M48
NEHPIGDC_00492	2.67e-308	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
NEHPIGDC_00493	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
NEHPIGDC_00494	4.74e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
NEHPIGDC_00495	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
NEHPIGDC_00496	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
NEHPIGDC_00497	7.53e-202	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEHPIGDC_00498	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
NEHPIGDC_00499	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_00500	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
NEHPIGDC_00501	1.75e-43	-	-	-	-	-	-	-	-
NEHPIGDC_00502	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NEHPIGDC_00503	1.65e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00504	9.33e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEHPIGDC_00505	2.59e-276	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEHPIGDC_00506	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NEHPIGDC_00507	1.32e-144	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NEHPIGDC_00508	8.94e-28	yxzF	-	-	-	-	-	-	-
NEHPIGDC_00509	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NEHPIGDC_00510	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
NEHPIGDC_00511	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPIGDC_00512	1.3e-49	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00513	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NEHPIGDC_00514	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NEHPIGDC_00515	2.39e-177	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_00516	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEHPIGDC_00517	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_00518	2.29e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
NEHPIGDC_00519	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_00520	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
NEHPIGDC_00521	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
NEHPIGDC_00522	5.61e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
NEHPIGDC_00523	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NEHPIGDC_00524	2.67e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEHPIGDC_00525	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
NEHPIGDC_00526	2.9e-293	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEHPIGDC_00527	1.46e-113	ywaE	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00528	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
NEHPIGDC_00529	5.37e-216	gspA	-	-	M	-	-	-	General stress
NEHPIGDC_00530	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NEHPIGDC_00531	1.69e-311	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00532	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NEHPIGDC_00533	2.5e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEHPIGDC_00534	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
NEHPIGDC_00535	8.07e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
NEHPIGDC_00536	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
NEHPIGDC_00537	5.03e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
NEHPIGDC_00538	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
NEHPIGDC_00539	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NEHPIGDC_00540	1.56e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00541	2.19e-183	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEHPIGDC_00542	7.07e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEHPIGDC_00543	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
NEHPIGDC_00544	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
NEHPIGDC_00545	1.04e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
NEHPIGDC_00546	5.99e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
NEHPIGDC_00547	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPIGDC_00548	2.13e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
NEHPIGDC_00550	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
NEHPIGDC_00551	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
NEHPIGDC_00552	2.27e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEHPIGDC_00553	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NEHPIGDC_00554	5.11e-49	ydaS	-	-	S	-	-	-	membrane
NEHPIGDC_00555	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NEHPIGDC_00556	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NEHPIGDC_00557	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NEHPIGDC_00558	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NEHPIGDC_00559	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
NEHPIGDC_00560	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NEHPIGDC_00561	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
NEHPIGDC_00562	9.87e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_00563	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NEHPIGDC_00565	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NEHPIGDC_00566	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
NEHPIGDC_00567	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_00568	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NEHPIGDC_00569	6.19e-39	ywdA	-	-	-	-	-	-	-
NEHPIGDC_00570	4.46e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEHPIGDC_00571	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NEHPIGDC_00572	5.9e-144	ywdD	-	-	-	-	-	-	-
NEHPIGDC_00574	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_00575	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEHPIGDC_00576	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NEHPIGDC_00577	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
NEHPIGDC_00578	1.53e-302	ywdJ	-	-	F	-	-	-	Xanthine uracil
NEHPIGDC_00579	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
NEHPIGDC_00580	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NEHPIGDC_00581	3.84e-185	spsA	-	-	M	-	-	-	Spore Coat
NEHPIGDC_00582	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
NEHPIGDC_00583	3.57e-282	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
NEHPIGDC_00584	1.41e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
NEHPIGDC_00585	4.59e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
NEHPIGDC_00586	1.18e-162	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
NEHPIGDC_00587	1.24e-234	spsG	-	-	M	-	-	-	Spore Coat
NEHPIGDC_00588	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NEHPIGDC_00589	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEHPIGDC_00590	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEHPIGDC_00591	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
NEHPIGDC_00592	2.64e-101	-	-	-	-	-	-	-	-
NEHPIGDC_00593	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NEHPIGDC_00594	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
NEHPIGDC_00595	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
NEHPIGDC_00596	1.77e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NEHPIGDC_00597	4.44e-274	ywfA	-	-	EGP	-	-	-	-transporter
NEHPIGDC_00598	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NEHPIGDC_00599	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NEHPIGDC_00600	3.83e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_00601	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NEHPIGDC_00602	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NEHPIGDC_00603	9e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NEHPIGDC_00604	9.66e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_00605	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
NEHPIGDC_00606	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
NEHPIGDC_00607	9.56e-212	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_00608	2.15e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NEHPIGDC_00609	3.04e-202	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
NEHPIGDC_00610	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
NEHPIGDC_00611	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
NEHPIGDC_00612	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
NEHPIGDC_00613	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
NEHPIGDC_00614	7.42e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00615	1.64e-301	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
NEHPIGDC_00617	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEHPIGDC_00618	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00619	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
NEHPIGDC_00620	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
NEHPIGDC_00621	7.83e-123	ywhD	-	-	S	-	-	-	YwhD family
NEHPIGDC_00622	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NEHPIGDC_00623	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NEHPIGDC_00624	3.49e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
NEHPIGDC_00625	2.03e-30	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
NEHPIGDC_00627	1.32e-106	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
NEHPIGDC_00628	3.85e-274	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
NEHPIGDC_00629	0.0	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
NEHPIGDC_00631	2.58e-312	-	-	-	L	-	-	-	Peptidase, M16
NEHPIGDC_00632	5.09e-278	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
NEHPIGDC_00633	6.61e-295	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
NEHPIGDC_00634	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NEHPIGDC_00636	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
NEHPIGDC_00637	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
NEHPIGDC_00638	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00639	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NEHPIGDC_00640	1.7e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NEHPIGDC_00641	2.3e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
NEHPIGDC_00642	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
NEHPIGDC_00643	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
NEHPIGDC_00644	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHPIGDC_00645	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
NEHPIGDC_00646	7.94e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
NEHPIGDC_00647	5.91e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
NEHPIGDC_00648	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHPIGDC_00649	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NEHPIGDC_00650	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
NEHPIGDC_00651	1.32e-57	ywjC	-	-	-	-	-	-	-
NEHPIGDC_00652	8.09e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NEHPIGDC_00653	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NEHPIGDC_00654	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
NEHPIGDC_00655	2.98e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
NEHPIGDC_00656	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEHPIGDC_00657	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEHPIGDC_00658	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
NEHPIGDC_00659	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
NEHPIGDC_00660	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
NEHPIGDC_00661	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEHPIGDC_00662	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHPIGDC_00663	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
NEHPIGDC_00664	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEHPIGDC_00665	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
NEHPIGDC_00666	1.41e-134	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NEHPIGDC_00667	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
NEHPIGDC_00668	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NEHPIGDC_00669	6.01e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NEHPIGDC_00670	1.39e-88	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_00671	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEHPIGDC_00672	8.46e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEHPIGDC_00674	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
NEHPIGDC_00675	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
NEHPIGDC_00676	3.62e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
NEHPIGDC_00677	5.8e-248	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEHPIGDC_00678	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NEHPIGDC_00679	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEHPIGDC_00680	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
NEHPIGDC_00681	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NEHPIGDC_00682	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEHPIGDC_00683	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEHPIGDC_00684	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
NEHPIGDC_00685	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NEHPIGDC_00686	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHPIGDC_00687	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEHPIGDC_00688	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEHPIGDC_00689	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEHPIGDC_00690	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEHPIGDC_00691	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEHPIGDC_00692	3.89e-72	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NEHPIGDC_00693	1.19e-112	ywmA	-	-	-	-	-	-	-
NEHPIGDC_00694	4.54e-45	ywzB	-	-	S	-	-	-	membrane
NEHPIGDC_00695	1.97e-173	ywmB	-	-	S	-	-	-	TATA-box binding
NEHPIGDC_00696	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEHPIGDC_00697	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
NEHPIGDC_00698	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NEHPIGDC_00699	1.02e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NEHPIGDC_00701	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NEHPIGDC_00702	6.25e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NEHPIGDC_00703	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NEHPIGDC_00704	1.12e-109	ywmF	-	-	S	-	-	-	Peptidase M50
NEHPIGDC_00705	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
NEHPIGDC_00706	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
NEHPIGDC_00707	1.85e-82	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
NEHPIGDC_00708	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NEHPIGDC_00709	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00710	5.89e-145	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NEHPIGDC_00711	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
NEHPIGDC_00712	3.28e-182	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
NEHPIGDC_00713	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEHPIGDC_00714	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
NEHPIGDC_00715	1.01e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
NEHPIGDC_00716	5.19e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
NEHPIGDC_00717	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NEHPIGDC_00718	1.63e-95	ywnJ	-	-	S	-	-	-	VanZ like family
NEHPIGDC_00719	1.21e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
NEHPIGDC_00720	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
NEHPIGDC_00721	6.5e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
NEHPIGDC_00722	1.62e-97	-	-	-	-	-	-	-	-
NEHPIGDC_00723	1.48e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
NEHPIGDC_00724	1.54e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
NEHPIGDC_00725	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
NEHPIGDC_00726	1.69e-311	ywoF	-	-	P	-	-	-	Right handed beta helix region
NEHPIGDC_00727	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_00728	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
NEHPIGDC_00729	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
NEHPIGDC_00730	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
NEHPIGDC_00731	6.89e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NEHPIGDC_00732	1.6e-179	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NEHPIGDC_00733	4.47e-256	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
NEHPIGDC_00734	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEHPIGDC_00735	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEHPIGDC_00736	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_00737	2.39e-221	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NEHPIGDC_00738	0.0	-	-	-	M	-	-	-	cell wall anchor domain
NEHPIGDC_00739	5.85e-107	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NEHPIGDC_00740	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
NEHPIGDC_00741	5.26e-88	ywpG	-	-	-	-	-	-	-
NEHPIGDC_00742	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
NEHPIGDC_00743	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NEHPIGDC_00744	1.24e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NEHPIGDC_00745	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NEHPIGDC_00746	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
NEHPIGDC_00747	3.6e-25	-	-	-	-	-	-	-	-
NEHPIGDC_00748	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
NEHPIGDC_00749	4.51e-156	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
NEHPIGDC_00750	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
NEHPIGDC_00751	2.21e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEHPIGDC_00752	8.46e-196	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
NEHPIGDC_00754	4.26e-51	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
NEHPIGDC_00755	2.04e-302	ywqJ	-	-	S	-	-	-	Pre-toxin TG
NEHPIGDC_00757	7.19e-149	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NEHPIGDC_00758	2.34e-209	-	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00759	5.23e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
NEHPIGDC_00761	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
NEHPIGDC_00762	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
NEHPIGDC_00763	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
NEHPIGDC_00764	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
NEHPIGDC_00765	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
NEHPIGDC_00766	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NEHPIGDC_00767	2.17e-16	-	-	-	-	-	-	-	-
NEHPIGDC_00768	9.22e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
NEHPIGDC_00769	2.73e-180	cotB	-	-	-	ko:K06325	-	ko00000	-
NEHPIGDC_00770	2.14e-162	ywrJ	-	-	-	-	-	-	-
NEHPIGDC_00771	1.13e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NEHPIGDC_00772	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
NEHPIGDC_00773	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NEHPIGDC_00774	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
NEHPIGDC_00775	3.57e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
NEHPIGDC_00776	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
NEHPIGDC_00777	4.64e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
NEHPIGDC_00778	5.22e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
NEHPIGDC_00779	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NEHPIGDC_00780	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NEHPIGDC_00781	4.61e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEHPIGDC_00782	3.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEHPIGDC_00783	7.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NEHPIGDC_00784	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
NEHPIGDC_00785	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
NEHPIGDC_00786	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NEHPIGDC_00787	2.29e-29	ywtC	-	-	-	-	-	-	-
NEHPIGDC_00788	3.22e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NEHPIGDC_00789	2.95e-204	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NEHPIGDC_00790	1.48e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00791	8.19e-316	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_00792	3.8e-274	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
NEHPIGDC_00793	2.5e-256	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NEHPIGDC_00794	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NEHPIGDC_00795	7.82e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NEHPIGDC_00796	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEHPIGDC_00797	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPIGDC_00798	6.69e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPIGDC_00799	5.68e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NEHPIGDC_00800	1.46e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NEHPIGDC_00801	5.02e-130	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NEHPIGDC_00802	6.82e-111	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NEHPIGDC_00803	1.88e-73	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
NEHPIGDC_00804	6.32e-167	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NEHPIGDC_00805	1.46e-134	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_00806	1.49e-102	-	-	-	-	-	-	-	-
NEHPIGDC_00807	6.73e-165	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_00808	3.08e-181	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEHPIGDC_00809	1.95e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
NEHPIGDC_00810	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NEHPIGDC_00811	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NEHPIGDC_00813	3.43e-118	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEHPIGDC_00814	1.48e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_00815	6.61e-278	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEHPIGDC_00816	1.16e-211	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NEHPIGDC_00817	9.07e-16	-	-	-	-	-	-	-	-
NEHPIGDC_00818	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
NEHPIGDC_00819	1.58e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_00820	9e-109	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_00821	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NEHPIGDC_00822	3.44e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_00823	5.68e-279	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
NEHPIGDC_00824	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEHPIGDC_00825	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
NEHPIGDC_00826	3.91e-145	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
NEHPIGDC_00827	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NEHPIGDC_00828	6.12e-299	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
NEHPIGDC_00829	5.69e-232	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NEHPIGDC_00830	3.81e-223	yvhJ	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00831	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
NEHPIGDC_00832	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NEHPIGDC_00833	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_00834	1.77e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00835	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NEHPIGDC_00836	1.04e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
NEHPIGDC_00837	2.64e-161	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
NEHPIGDC_00838	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
NEHPIGDC_00839	4.32e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
NEHPIGDC_00840	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
NEHPIGDC_00841	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
NEHPIGDC_00842	3.8e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
NEHPIGDC_00843	1.39e-91	yviE	-	-	-	-	-	-	-
NEHPIGDC_00844	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NEHPIGDC_00845	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NEHPIGDC_00846	1.43e-124	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NEHPIGDC_00847	9.41e-69	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
NEHPIGDC_00848	3.13e-313	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NEHPIGDC_00849	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
NEHPIGDC_00850	9.58e-08	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
NEHPIGDC_00851	1e-66	-	-	-	-	-	-	-	-
NEHPIGDC_00852	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEHPIGDC_00853	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEHPIGDC_00854	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEHPIGDC_00855	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NEHPIGDC_00856	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
NEHPIGDC_00857	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
NEHPIGDC_00858	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NEHPIGDC_00859	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NEHPIGDC_00860	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
NEHPIGDC_00861	3.86e-281	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEHPIGDC_00862	3.16e-297	yvkA	-	-	P	-	-	-	-transporter
NEHPIGDC_00863	5.81e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00864	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
NEHPIGDC_00865	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_00866	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEHPIGDC_00867	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEHPIGDC_00868	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NEHPIGDC_00869	2.73e-46	yvkN	-	-	-	-	-	-	-
NEHPIGDC_00870	8.09e-65	yvlA	-	-	-	-	-	-	-
NEHPIGDC_00871	1.66e-220	yvlB	-	-	S	-	-	-	Putative adhesin
NEHPIGDC_00872	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
NEHPIGDC_00873	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
NEHPIGDC_00874	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEHPIGDC_00875	5.1e-113	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_00876	7.15e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NEHPIGDC_00877	9.32e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NEHPIGDC_00878	9.4e-110	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_00879	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
NEHPIGDC_00880	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NEHPIGDC_00881	2.49e-84	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEHPIGDC_00882	3.57e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NEHPIGDC_00883	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEHPIGDC_00884	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEHPIGDC_00885	2.06e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
NEHPIGDC_00886	8.74e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NEHPIGDC_00887	5.29e-121	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NEHPIGDC_00888	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
NEHPIGDC_00889	6.12e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
NEHPIGDC_00890	6.64e-279	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NEHPIGDC_00891	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NEHPIGDC_00892	3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEHPIGDC_00893	8.22e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NEHPIGDC_00894	1.2e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEHPIGDC_00895	3.95e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEHPIGDC_00896	9.74e-177	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEHPIGDC_00897	5.91e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
NEHPIGDC_00898	1.76e-90	-	-	-	-	-	-	-	-
NEHPIGDC_00899	1.23e-109	-	-	-	-	-	-	-	-
NEHPIGDC_00900	0.0	-	-	-	-	-	-	-	-
NEHPIGDC_00902	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NEHPIGDC_00903	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
NEHPIGDC_00904	2.18e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
NEHPIGDC_00905	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEHPIGDC_00906	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NEHPIGDC_00907	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NEHPIGDC_00908	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NEHPIGDC_00909	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NEHPIGDC_00910	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
NEHPIGDC_00911	2.3e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
NEHPIGDC_00912	1.32e-43	-	-	-	-	-	-	-	-
NEHPIGDC_00913	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_00914	9.29e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NEHPIGDC_00915	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_00916	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NEHPIGDC_00917	9.43e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPIGDC_00918	3.73e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NEHPIGDC_00919	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
NEHPIGDC_00920	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NEHPIGDC_00921	5.37e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NEHPIGDC_00922	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00923	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
NEHPIGDC_00924	8.1e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NEHPIGDC_00925	6.09e-311	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NEHPIGDC_00926	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NEHPIGDC_00927	6.86e-198	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
NEHPIGDC_00928	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
NEHPIGDC_00929	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NEHPIGDC_00930	1.01e-156	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NEHPIGDC_00931	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEHPIGDC_00933	9.45e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
NEHPIGDC_00934	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
NEHPIGDC_00935	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
NEHPIGDC_00936	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
NEHPIGDC_00937	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NEHPIGDC_00938	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00939	0.0	ybeC	-	-	E	-	-	-	amino acid
NEHPIGDC_00940	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NEHPIGDC_00941	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
NEHPIGDC_00942	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
NEHPIGDC_00943	8.37e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NEHPIGDC_00944	1.5e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
NEHPIGDC_00945	3.13e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
NEHPIGDC_00947	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
NEHPIGDC_00948	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
NEHPIGDC_00949	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
NEHPIGDC_00950	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
NEHPIGDC_00951	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
NEHPIGDC_00952	7.77e-282	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
NEHPIGDC_00953	8.8e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_00954	3.8e-274	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NEHPIGDC_00955	3.59e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
NEHPIGDC_00956	7.05e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NEHPIGDC_00957	1.57e-258	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
NEHPIGDC_00958	1.25e-241	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_00959	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_00960	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NEHPIGDC_00961	7.27e-73	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NEHPIGDC_00962	6.12e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
NEHPIGDC_00963	9.86e-237	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
NEHPIGDC_00964	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
NEHPIGDC_00965	2.36e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NEHPIGDC_00966	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NEHPIGDC_00967	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
NEHPIGDC_00968	1.3e-236	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_00969	4.7e-287	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NEHPIGDC_00970	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NEHPIGDC_00971	1.1e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NEHPIGDC_00972	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
NEHPIGDC_00973	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NEHPIGDC_00974	6.4e-251	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
NEHPIGDC_00975	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
NEHPIGDC_00976	1.34e-205	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NEHPIGDC_00977	2.04e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NEHPIGDC_00978	2.91e-256	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_00979	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_00980	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NEHPIGDC_00981	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NEHPIGDC_00982	1.45e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NEHPIGDC_00983	2.68e-252	-	-	-	S	-	-	-	Glycosyl hydrolase
NEHPIGDC_00984	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_00985	3.93e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_00986	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_00987	2.98e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_00988	1.24e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
NEHPIGDC_00989	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_00990	5.69e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NEHPIGDC_00991	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEHPIGDC_00992	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NEHPIGDC_00993	2.48e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEHPIGDC_00994	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
NEHPIGDC_00995	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEHPIGDC_00996	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
NEHPIGDC_00997	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
NEHPIGDC_00998	3.95e-157	yvbI	-	-	M	-	-	-	Membrane
NEHPIGDC_00999	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
NEHPIGDC_01000	1.13e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
NEHPIGDC_01001	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NEHPIGDC_01002	2.27e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NEHPIGDC_01003	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NEHPIGDC_01004	2.58e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHPIGDC_01005	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NEHPIGDC_01006	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NEHPIGDC_01007	3.64e-271	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NEHPIGDC_01008	1.27e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NEHPIGDC_01009	1.37e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NEHPIGDC_01010	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NEHPIGDC_01011	7.34e-317	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_01012	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
NEHPIGDC_01013	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NEHPIGDC_01014	2.36e-91	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
NEHPIGDC_01015	3.44e-48	yvzC	-	-	K	-	-	-	transcriptional
NEHPIGDC_01016	3.32e-193	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
NEHPIGDC_01017	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
NEHPIGDC_01018	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
NEHPIGDC_01019	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEHPIGDC_01020	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NEHPIGDC_01022	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01023	7.02e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEHPIGDC_01024	2.04e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
NEHPIGDC_01025	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
NEHPIGDC_01026	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
NEHPIGDC_01027	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHPIGDC_01028	1.71e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NEHPIGDC_01029	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
NEHPIGDC_01030	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
NEHPIGDC_01031	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NEHPIGDC_01032	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NEHPIGDC_01033	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
NEHPIGDC_01034	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
NEHPIGDC_01035	3.32e-139	yvgT	-	-	S	-	-	-	membrane
NEHPIGDC_01037	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEHPIGDC_01038	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NEHPIGDC_01039	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NEHPIGDC_01040	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
NEHPIGDC_01041	7.97e-113	yvgO	-	-	-	-	-	-	-
NEHPIGDC_01042	2.63e-202	yvgN	-	-	S	-	-	-	reductase
NEHPIGDC_01043	6.08e-154	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
NEHPIGDC_01044	6.3e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
NEHPIGDC_01045	3.77e-216	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
NEHPIGDC_01046	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
NEHPIGDC_01047	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NEHPIGDC_01048	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
NEHPIGDC_01049	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NEHPIGDC_01051	5.41e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEHPIGDC_01052	1.41e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01053	5.34e-223	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01054	3.98e-189	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NEHPIGDC_01055	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
NEHPIGDC_01056	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01057	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NEHPIGDC_01058	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
NEHPIGDC_01059	3.22e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
NEHPIGDC_01060	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
NEHPIGDC_01061	1.66e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
NEHPIGDC_01062	6.16e-33	-	-	-	-	-	-	-	-
NEHPIGDC_01063	9.05e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_01064	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_01065	3.11e-218	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
NEHPIGDC_01066	2.12e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01067	4.06e-216	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NEHPIGDC_01068	4.47e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01069	6.34e-310	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NEHPIGDC_01070	1.93e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
NEHPIGDC_01071	6.23e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_01072	1.77e-81	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
NEHPIGDC_01073	9.94e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NEHPIGDC_01074	2.19e-176	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NEHPIGDC_01075	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
NEHPIGDC_01076	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01077	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_01078	2.01e-248	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NEHPIGDC_01079	2.9e-253	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NEHPIGDC_01080	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NEHPIGDC_01081	4.48e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
NEHPIGDC_01082	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEHPIGDC_01083	1.77e-203	yuxN	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01084	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01085	9.09e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_01086	9.21e-304	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEHPIGDC_01087	1.07e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
NEHPIGDC_01088	1.06e-194	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01089	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
NEHPIGDC_01090	2.01e-87	-	-	-	S	-	-	-	YusW-like protein
NEHPIGDC_01091	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NEHPIGDC_01092	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
NEHPIGDC_01093	6.91e-203	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
NEHPIGDC_01094	2.46e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01095	4.16e-85	yusQ	-	-	S	-	-	-	Tautomerase enzyme
NEHPIGDC_01096	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
NEHPIGDC_01097	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
NEHPIGDC_01098	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
NEHPIGDC_01099	2.23e-54	-	-	-	-	-	-	-	-
NEHPIGDC_01100	2.09e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NEHPIGDC_01101	2.86e-14	-	-	-	S	-	-	-	YuzL-like protein
NEHPIGDC_01102	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
NEHPIGDC_01103	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
NEHPIGDC_01104	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NEHPIGDC_01105	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NEHPIGDC_01106	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NEHPIGDC_01107	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
NEHPIGDC_01108	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
NEHPIGDC_01109	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
NEHPIGDC_01110	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
NEHPIGDC_01111	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEHPIGDC_01112	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NEHPIGDC_01113	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NEHPIGDC_01114	5.44e-81	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NEHPIGDC_01115	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NEHPIGDC_01116	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
NEHPIGDC_01117	1.63e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEHPIGDC_01118	5.15e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
NEHPIGDC_01119	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
NEHPIGDC_01120	6.91e-84	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_01121	4.76e-56	-	-	-	-	-	-	-	-
NEHPIGDC_01123	4.87e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
NEHPIGDC_01124	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
NEHPIGDC_01125	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NEHPIGDC_01126	2.87e-307	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
NEHPIGDC_01127	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_01128	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NEHPIGDC_01129	6.46e-207	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
NEHPIGDC_01130	1.02e-173	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
NEHPIGDC_01131	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_01132	6.53e-218	bsn	-	-	L	-	-	-	Ribonuclease
NEHPIGDC_01133	4.82e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NEHPIGDC_01134	8.51e-306	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NEHPIGDC_01136	5.12e-243	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NEHPIGDC_01137	6.18e-143	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
NEHPIGDC_01138	2.58e-189	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NEHPIGDC_01139	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NEHPIGDC_01140	2.62e-126	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NEHPIGDC_01141	1.72e-71	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NEHPIGDC_01142	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NEHPIGDC_01143	4.52e-283	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
NEHPIGDC_01144	1.46e-300	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
NEHPIGDC_01145	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
NEHPIGDC_01146	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NEHPIGDC_01147	1.07e-79	yunG	-	-	-	-	-	-	-
NEHPIGDC_01148	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
NEHPIGDC_01149	2.65e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEHPIGDC_01150	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NEHPIGDC_01151	1.39e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
NEHPIGDC_01152	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
NEHPIGDC_01153	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
NEHPIGDC_01154	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NEHPIGDC_01155	1.29e-142	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEHPIGDC_01156	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01157	1.96e-98	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
NEHPIGDC_01158	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEHPIGDC_01159	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
NEHPIGDC_01160	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
NEHPIGDC_01161	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NEHPIGDC_01162	2.4e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NEHPIGDC_01163	4.96e-219	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEHPIGDC_01164	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
NEHPIGDC_01165	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
NEHPIGDC_01166	6.61e-75	yuzD	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01167	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NEHPIGDC_01168	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
NEHPIGDC_01169	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NEHPIGDC_01170	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEHPIGDC_01171	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
NEHPIGDC_01172	5.66e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_01173	9.91e-150	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
NEHPIGDC_01174	3.7e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEHPIGDC_01176	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
NEHPIGDC_01177	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NEHPIGDC_01178	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
NEHPIGDC_01179	1.39e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01180	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
NEHPIGDC_01181	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NEHPIGDC_01182	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
NEHPIGDC_01183	6.84e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
NEHPIGDC_01184	1.37e-156	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
NEHPIGDC_01185	4.25e-211	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
NEHPIGDC_01186	2.89e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01187	2.1e-290	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
NEHPIGDC_01188	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
NEHPIGDC_01189	3.15e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
NEHPIGDC_01190	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_01191	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
NEHPIGDC_01192	3.44e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
NEHPIGDC_01193	1.64e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NEHPIGDC_01194	4.7e-289	yukF	-	-	QT	-	-	-	Transcriptional regulator
NEHPIGDC_01195	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
NEHPIGDC_01196	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
NEHPIGDC_01197	2.47e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
NEHPIGDC_01198	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NEHPIGDC_01199	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
NEHPIGDC_01200	2.08e-95	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
NEHPIGDC_01201	2.9e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_01202	7.78e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NEHPIGDC_01203	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NEHPIGDC_01204	4.83e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
NEHPIGDC_01205	2.73e-244	yueF	-	-	S	-	-	-	transporter activity
NEHPIGDC_01206	7.15e-43	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
NEHPIGDC_01207	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
NEHPIGDC_01208	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NEHPIGDC_01209	3.27e-134	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
NEHPIGDC_01210	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEHPIGDC_01211	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
NEHPIGDC_01212	8.73e-09	yuzC	-	-	-	-	-	-	-
NEHPIGDC_01213	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
NEHPIGDC_01214	1.36e-179	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
NEHPIGDC_01216	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01217	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_01218	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
NEHPIGDC_01219	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
NEHPIGDC_01220	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEHPIGDC_01221	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEHPIGDC_01222	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEHPIGDC_01223	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEHPIGDC_01224	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NEHPIGDC_01225	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NEHPIGDC_01226	1.42e-21	-	-	-	-	-	-	-	-
NEHPIGDC_01227	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
NEHPIGDC_01228	4.9e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NEHPIGDC_01229	9.08e-237	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NEHPIGDC_01230	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01231	9.13e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
NEHPIGDC_01232	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NEHPIGDC_01233	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NEHPIGDC_01234	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
NEHPIGDC_01235	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01236	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
NEHPIGDC_01237	8.9e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
NEHPIGDC_01239	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
NEHPIGDC_01240	3.54e-91	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
NEHPIGDC_01241	1.06e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01242	4.53e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NEHPIGDC_01243	1.53e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
NEHPIGDC_01244	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
NEHPIGDC_01245	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01246	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
NEHPIGDC_01247	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NEHPIGDC_01248	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
NEHPIGDC_01249	8.16e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
NEHPIGDC_01250	9.22e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
NEHPIGDC_01251	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NEHPIGDC_01253	1.72e-94	yugN	-	-	S	-	-	-	YugN-like family
NEHPIGDC_01254	2.06e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
NEHPIGDC_01255	3.39e-67	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
NEHPIGDC_01256	1.58e-50	-	-	-	-	-	-	-	-
NEHPIGDC_01257	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
NEHPIGDC_01258	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NEHPIGDC_01259	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NEHPIGDC_01260	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
NEHPIGDC_01261	5.85e-47	-	-	-	-	-	-	-	-
NEHPIGDC_01262	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NEHPIGDC_01263	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_01264	5.64e-296	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_01265	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_01266	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_01267	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
NEHPIGDC_01268	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NEHPIGDC_01269	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEHPIGDC_01270	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NEHPIGDC_01271	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
NEHPIGDC_01272	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NEHPIGDC_01273	7.02e-252	yubA	-	-	S	-	-	-	transporter activity
NEHPIGDC_01274	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEHPIGDC_01276	2.29e-112	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
NEHPIGDC_01277	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
NEHPIGDC_01278	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEHPIGDC_01279	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
NEHPIGDC_01280	7.21e-299	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
NEHPIGDC_01281	1.5e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NEHPIGDC_01282	5.83e-118	yuaB	-	-	-	-	-	-	-
NEHPIGDC_01283	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
NEHPIGDC_01284	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NEHPIGDC_01285	1.43e-290	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
NEHPIGDC_01286	1.42e-137	yuaD	-	-	-	-	-	-	-
NEHPIGDC_01287	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
NEHPIGDC_01288	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
NEHPIGDC_01289	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
NEHPIGDC_01290	3.31e-120	-	-	-	M	-	-	-	FR47-like protein
NEHPIGDC_01291	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
NEHPIGDC_01294	2.7e-231	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NEHPIGDC_01295	2.13e-111	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
NEHPIGDC_01296	3.98e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
NEHPIGDC_01297	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NEHPIGDC_01298	1.1e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEHPIGDC_01299	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NEHPIGDC_01300	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NEHPIGDC_01301	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEHPIGDC_01302	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEHPIGDC_01303	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEHPIGDC_01304	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
NEHPIGDC_01305	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEHPIGDC_01306	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEHPIGDC_01307	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEHPIGDC_01308	0.0	-	-	-	-	-	-	-	-
NEHPIGDC_01310	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
NEHPIGDC_01311	3.55e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NEHPIGDC_01312	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
NEHPIGDC_01313	2.86e-219	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NEHPIGDC_01314	1.54e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
NEHPIGDC_01315	1.04e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEHPIGDC_01316	7.06e-173	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
NEHPIGDC_01317	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
NEHPIGDC_01318	2.3e-238	-	-	-	S	-	-	-	Ion transport 2 domain protein
NEHPIGDC_01319	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_01320	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
NEHPIGDC_01321	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
NEHPIGDC_01322	1.14e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
NEHPIGDC_01324	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
NEHPIGDC_01325	7.25e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
NEHPIGDC_01326	5.85e-228	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
NEHPIGDC_01327	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
NEHPIGDC_01328	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_01329	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEHPIGDC_01330	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
NEHPIGDC_01331	2.07e-281	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NEHPIGDC_01332	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
NEHPIGDC_01333	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NEHPIGDC_01334	1.7e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NEHPIGDC_01335	2.78e-163	yebC	-	-	M	-	-	-	Membrane
NEHPIGDC_01337	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
NEHPIGDC_01338	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
NEHPIGDC_01339	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEHPIGDC_01340	2.69e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEHPIGDC_01341	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEHPIGDC_01342	2.9e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NEHPIGDC_01343	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPIGDC_01344	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPIGDC_01345	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEHPIGDC_01346	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEHPIGDC_01347	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NEHPIGDC_01348	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEHPIGDC_01349	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NEHPIGDC_01350	1.99e-298	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NEHPIGDC_01351	1.06e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
NEHPIGDC_01352	4.56e-288	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
NEHPIGDC_01353	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
NEHPIGDC_01354	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
NEHPIGDC_01355	2.26e-242	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
NEHPIGDC_01356	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01357	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
NEHPIGDC_01358	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NEHPIGDC_01359	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NEHPIGDC_01360	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEHPIGDC_01361	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
NEHPIGDC_01362	1.22e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
NEHPIGDC_01363	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
NEHPIGDC_01364	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPIGDC_01365	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHPIGDC_01366	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEHPIGDC_01367	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEHPIGDC_01368	1.26e-191	yerO	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01369	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEHPIGDC_01370	1.88e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NEHPIGDC_01371	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHPIGDC_01372	3.09e-245	-	-	-	L	-	-	-	AAA ATPase domain
NEHPIGDC_01373	4.14e-141	-	-	-	L	-	-	-	AAA domain
NEHPIGDC_01374	7.31e-88	-	-	-	-	-	-	-	-
NEHPIGDC_01375	5.78e-76	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEHPIGDC_01376	4.24e-05	-	-	-	-	-	-	-	-
NEHPIGDC_01377	9.86e-54	-	-	-	S	-	-	-	Immunity protein 22
NEHPIGDC_01378	8.28e-228	-	-	-	S	-	-	-	Bacterial EndoU nuclease
NEHPIGDC_01380	1.76e-70	-	-	-	L	-	-	-	endonuclease activity
NEHPIGDC_01381	1.69e-37	-	-	-	L	-	-	-	endonuclease activity
NEHPIGDC_01382	1.68e-14	-	-	-	S	-	-	-	Lysozyme inhibitor LprI
NEHPIGDC_01383	7.06e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
NEHPIGDC_01385	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
NEHPIGDC_01387	3.46e-130	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_01388	3.92e-104	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
NEHPIGDC_01389	1.23e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
NEHPIGDC_01390	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
NEHPIGDC_01391	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
NEHPIGDC_01392	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
NEHPIGDC_01393	9.78e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NEHPIGDC_01394	2.28e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
NEHPIGDC_01395	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01396	1.98e-257	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NEHPIGDC_01397	4.82e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEHPIGDC_01398	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_01399	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_01400	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NEHPIGDC_01401	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01402	9.4e-167	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEHPIGDC_01403	7.22e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
NEHPIGDC_01404	4.02e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NEHPIGDC_01405	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
NEHPIGDC_01406	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
NEHPIGDC_01407	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEHPIGDC_01408	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NEHPIGDC_01409	0.0	yetA	-	-	-	-	-	-	-
NEHPIGDC_01410	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEHPIGDC_01411	3.25e-224	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NEHPIGDC_01412	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_01413	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NEHPIGDC_01414	3.66e-157	yetF	-	-	S	-	-	-	membrane
NEHPIGDC_01415	4.5e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
NEHPIGDC_01416	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_01417	1.75e-44	-	-	-	-	-	-	-	-
NEHPIGDC_01418	1.25e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEHPIGDC_01419	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
NEHPIGDC_01420	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NEHPIGDC_01421	8.15e-65	yetM	-	-	CH	-	-	-	FAD binding domain
NEHPIGDC_01422	3.98e-172	-	-	-	M	-	-	-	Membrane
NEHPIGDC_01423	1.67e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
NEHPIGDC_01424	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
NEHPIGDC_01425	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NEHPIGDC_01426	9.83e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
NEHPIGDC_01427	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
NEHPIGDC_01428	1.1e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
NEHPIGDC_01429	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_01430	3.72e-240	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
NEHPIGDC_01431	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_01432	2.13e-167	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NEHPIGDC_01433	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
NEHPIGDC_01434	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEHPIGDC_01435	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
NEHPIGDC_01436	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEHPIGDC_01437	1.31e-98	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
NEHPIGDC_01438	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
NEHPIGDC_01439	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
NEHPIGDC_01440	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEHPIGDC_01441	2.42e-262	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
NEHPIGDC_01442	2.55e-105	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
NEHPIGDC_01443	9.91e-241	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
NEHPIGDC_01444	4.92e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEHPIGDC_01445	0.0	pkn1	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NEHPIGDC_01446	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEHPIGDC_01447	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01448	4.72e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01449	3.36e-220	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NEHPIGDC_01450	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
NEHPIGDC_01451	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
NEHPIGDC_01452	1.73e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
NEHPIGDC_01453	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NEHPIGDC_01454	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NEHPIGDC_01455	1.55e-151	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NEHPIGDC_01456	2.3e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NEHPIGDC_01457	1.26e-286	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NEHPIGDC_01458	4.87e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NEHPIGDC_01459	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NEHPIGDC_01460	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NEHPIGDC_01461	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01462	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
NEHPIGDC_01463	6.9e-27	yflI	-	-	-	-	-	-	-
NEHPIGDC_01464	3.63e-66	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
NEHPIGDC_01465	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NEHPIGDC_01466	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NEHPIGDC_01467	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NEHPIGDC_01468	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
NEHPIGDC_01469	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NEHPIGDC_01470	1.36e-32	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
NEHPIGDC_01471	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_01472	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
NEHPIGDC_01473	7.17e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
NEHPIGDC_01474	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
NEHPIGDC_01475	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NEHPIGDC_01476	7.78e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
NEHPIGDC_01477	2.07e-264	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_01478	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
NEHPIGDC_01479	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEHPIGDC_01480	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
NEHPIGDC_01481	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NEHPIGDC_01482	1.64e-12	-	-	-	-	-	-	-	-
NEHPIGDC_01483	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_01484	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
NEHPIGDC_01485	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
NEHPIGDC_01486	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
NEHPIGDC_01487	5.9e-282	yfkA	-	-	S	-	-	-	YfkB-like domain
NEHPIGDC_01488	3.26e-36	yfjT	-	-	-	-	-	-	-
NEHPIGDC_01489	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
NEHPIGDC_01490	1.96e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NEHPIGDC_01491	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
NEHPIGDC_01492	3.76e-212	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NEHPIGDC_01493	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEHPIGDC_01494	1.65e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHPIGDC_01495	8.83e-107	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEHPIGDC_01497	2.75e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEHPIGDC_01498	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEHPIGDC_01499	9.61e-255	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEHPIGDC_01500	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEHPIGDC_01501	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
NEHPIGDC_01502	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
NEHPIGDC_01503	3.54e-73	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
NEHPIGDC_01504	1.78e-103	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
NEHPIGDC_01505	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
NEHPIGDC_01506	4.15e-184	yfjC	-	-	-	-	-	-	-
NEHPIGDC_01507	1.94e-270	yfjB	-	-	-	-	-	-	-
NEHPIGDC_01508	1.6e-60	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
NEHPIGDC_01509	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NEHPIGDC_01510	2.13e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NEHPIGDC_01511	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_01512	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
NEHPIGDC_01513	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NEHPIGDC_01514	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NEHPIGDC_01515	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
NEHPIGDC_01516	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NEHPIGDC_01518	6.63e-270	baeS	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_01519	1.74e-145	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
NEHPIGDC_01520	1.94e-217	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01521	2.47e-272	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEHPIGDC_01522	1.15e-260	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NEHPIGDC_01523	1.89e-128	padR	-	-	K	-	-	-	transcriptional
NEHPIGDC_01524	2.63e-126	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NEHPIGDC_01525	6.57e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NEHPIGDC_01526	3.3e-138	yfiR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01527	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
NEHPIGDC_01528	2.7e-126	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
NEHPIGDC_01529	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
NEHPIGDC_01530	5.39e-106	yfiV	-	-	K	-	-	-	transcriptional
NEHPIGDC_01531	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEHPIGDC_01532	1.1e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NEHPIGDC_01533	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01534	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_01535	1.79e-213	yfhB	-	-	S	-	-	-	PhzF family
NEHPIGDC_01536	2.36e-137	yfhC	-	-	C	-	-	-	nitroreductase
NEHPIGDC_01537	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
NEHPIGDC_01539	3.79e-220	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
NEHPIGDC_01540	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NEHPIGDC_01541	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
NEHPIGDC_01543	2.85e-267	yfhI	-	-	EGP	-	-	-	-transporter
NEHPIGDC_01544	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
NEHPIGDC_01545	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
NEHPIGDC_01546	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
NEHPIGDC_01547	1.27e-65	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
NEHPIGDC_01548	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
NEHPIGDC_01549	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_01550	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NEHPIGDC_01551	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
NEHPIGDC_01552	2.17e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
NEHPIGDC_01553	1.73e-48	yfhS	-	-	-	-	-	-	-
NEHPIGDC_01554	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_01555	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
NEHPIGDC_01556	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
NEHPIGDC_01557	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NEHPIGDC_01558	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
NEHPIGDC_01559	1.63e-237	ygaE	-	-	S	-	-	-	Membrane
NEHPIGDC_01560	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NEHPIGDC_01561	1.19e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
NEHPIGDC_01562	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NEHPIGDC_01563	1.57e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
NEHPIGDC_01564	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
NEHPIGDC_01581	1.83e-184	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
NEHPIGDC_01582	3.88e-37	-	-	-	-	-	-	-	-
NEHPIGDC_01583	6.95e-173	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
NEHPIGDC_01584	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEHPIGDC_01585	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
NEHPIGDC_01587	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NEHPIGDC_01588	1.43e-175	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NEHPIGDC_01589	9.85e-217	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
NEHPIGDC_01590	2.39e-189	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NEHPIGDC_01591	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
NEHPIGDC_01593	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHPIGDC_01594	2.79e-102	ygaO	-	-	-	-	-	-	-
NEHPIGDC_01595	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_01597	1.92e-147	yhzB	-	-	S	-	-	-	B3/4 domain
NEHPIGDC_01598	5.09e-285	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NEHPIGDC_01599	1.6e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
NEHPIGDC_01600	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEHPIGDC_01601	5.64e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
NEHPIGDC_01602	2.17e-94	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
NEHPIGDC_01603	2.46e-104	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
NEHPIGDC_01604	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
NEHPIGDC_01605	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
NEHPIGDC_01606	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
NEHPIGDC_01607	3.8e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
NEHPIGDC_01608	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NEHPIGDC_01609	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
NEHPIGDC_01610	3.24e-58	yhcC	-	-	-	-	-	-	-
NEHPIGDC_01611	4.14e-69	-	-	-	-	-	-	-	-
NEHPIGDC_01612	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_01613	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01614	4.37e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01615	3.45e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEHPIGDC_01616	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
NEHPIGDC_01617	1.34e-195	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NEHPIGDC_01618	7.92e-248	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
NEHPIGDC_01619	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHPIGDC_01620	1.13e-70	yhcM	-	-	-	-	-	-	-
NEHPIGDC_01621	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEHPIGDC_01622	3.96e-227	yhcP	-	-	-	-	-	-	-
NEHPIGDC_01623	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
NEHPIGDC_01624	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NEHPIGDC_01625	3.07e-135	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
NEHPIGDC_01626	1.12e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NEHPIGDC_01627	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
NEHPIGDC_01628	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
NEHPIGDC_01629	1.02e-153	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
NEHPIGDC_01630	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NEHPIGDC_01631	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEHPIGDC_01632	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NEHPIGDC_01633	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NEHPIGDC_01634	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEHPIGDC_01635	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NEHPIGDC_01636	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
NEHPIGDC_01637	3.63e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_01638	7.73e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_01639	9.43e-116	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
NEHPIGDC_01640	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
NEHPIGDC_01641	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
NEHPIGDC_01642	8e-274	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NEHPIGDC_01643	1.13e-98	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
NEHPIGDC_01644	2.5e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
NEHPIGDC_01645	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
NEHPIGDC_01646	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NEHPIGDC_01647	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NEHPIGDC_01648	2.01e-209	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_01649	1.84e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NEHPIGDC_01650	5.51e-206	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_01651	2.06e-315	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
NEHPIGDC_01652	8.66e-310	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NEHPIGDC_01653	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_01654	7.13e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_01655	6.07e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
NEHPIGDC_01656	3.54e-257	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
NEHPIGDC_01657	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_01658	1.93e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
NEHPIGDC_01659	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NEHPIGDC_01660	2.54e-303	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NEHPIGDC_01661	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
NEHPIGDC_01662	2.42e-282	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NEHPIGDC_01663	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NEHPIGDC_01664	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHPIGDC_01665	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEHPIGDC_01666	7.42e-172	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NEHPIGDC_01667	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
NEHPIGDC_01668	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
NEHPIGDC_01669	4.66e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NEHPIGDC_01670	5.7e-200	nodB1	-	-	G	-	-	-	deacetylase
NEHPIGDC_01671	3.69e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NEHPIGDC_01672	8.87e-304	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NEHPIGDC_01673	1.29e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
NEHPIGDC_01674	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NEHPIGDC_01675	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NEHPIGDC_01676	3.31e-143	yheG	-	-	GM	-	-	-	NAD(P)H-binding
NEHPIGDC_01677	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
NEHPIGDC_01678	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
NEHPIGDC_01679	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
NEHPIGDC_01680	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
NEHPIGDC_01681	1.69e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
NEHPIGDC_01682	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NEHPIGDC_01683	2.15e-260	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
NEHPIGDC_01684	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NEHPIGDC_01685	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
NEHPIGDC_01686	2.63e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
NEHPIGDC_01687	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
NEHPIGDC_01689	1.6e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
NEHPIGDC_01690	2.29e-36	-	-	-	S	-	-	-	YhzD-like protein
NEHPIGDC_01691	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_01692	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
NEHPIGDC_01693	6.11e-297	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
NEHPIGDC_01694	0.0	yhaN	-	-	L	-	-	-	AAA domain
NEHPIGDC_01695	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
NEHPIGDC_01696	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
NEHPIGDC_01697	6.57e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEHPIGDC_01698	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
NEHPIGDC_01699	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
NEHPIGDC_01700	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
NEHPIGDC_01701	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
NEHPIGDC_01702	9.66e-30	-	-	-	-	-	-	-	-
NEHPIGDC_01703	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
NEHPIGDC_01704	7.19e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEHPIGDC_01705	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NEHPIGDC_01706	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
NEHPIGDC_01707	1.27e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NEHPIGDC_01708	2.38e-160	ecsC	-	-	S	-	-	-	EcsC protein family
NEHPIGDC_01709	1.32e-292	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NEHPIGDC_01710	3.29e-313	yhfA	-	-	C	-	-	-	membrane
NEHPIGDC_01711	1.33e-23	-	-	-	C	-	-	-	Rubrerythrin
NEHPIGDC_01712	2.18e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NEHPIGDC_01713	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NEHPIGDC_01714	3.17e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NEHPIGDC_01715	3.41e-231	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NEHPIGDC_01716	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NEHPIGDC_01717	2.36e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_01718	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
NEHPIGDC_01719	7.21e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHPIGDC_01720	5.4e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
NEHPIGDC_01721	8.97e-252	yhfE	-	-	G	-	-	-	peptidase M42
NEHPIGDC_01722	6.22e-93	-	-	-	S	-	-	-	ASCH
NEHPIGDC_01723	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHPIGDC_01724	3.43e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NEHPIGDC_01725	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NEHPIGDC_01726	7.43e-144	yhfK	-	-	GM	-	-	-	NmrA-like family
NEHPIGDC_01727	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
NEHPIGDC_01728	2.78e-85	yhfM	-	-	-	-	-	-	-
NEHPIGDC_01729	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
NEHPIGDC_01730	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NEHPIGDC_01731	2.54e-101	-	-	-	K	-	-	-	acetyltransferase
NEHPIGDC_01732	1.39e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
NEHPIGDC_01733	2.77e-223	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NEHPIGDC_01734	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
NEHPIGDC_01735	4.96e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NEHPIGDC_01736	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
NEHPIGDC_01737	8.51e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NEHPIGDC_01738	2.62e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
NEHPIGDC_01739	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
NEHPIGDC_01740	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_01741	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
NEHPIGDC_01742	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
NEHPIGDC_01743	2.55e-216	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_01744	5e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
NEHPIGDC_01745	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPIGDC_01746	9.31e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
NEHPIGDC_01747	2.57e-78	yhjD	-	-	-	-	-	-	-
NEHPIGDC_01748	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_01749	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEHPIGDC_01750	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
NEHPIGDC_01751	2.32e-121	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_01752	3.64e-272	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
NEHPIGDC_01753	2.3e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NEHPIGDC_01754	4.36e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
NEHPIGDC_01755	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
NEHPIGDC_01756	4.36e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01757	5.88e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
NEHPIGDC_01758	9.56e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NEHPIGDC_01759	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
NEHPIGDC_01760	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
NEHPIGDC_01761	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
NEHPIGDC_01762	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NEHPIGDC_01763	1.2e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEHPIGDC_01764	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
NEHPIGDC_01765	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
NEHPIGDC_01766	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
NEHPIGDC_01767	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
NEHPIGDC_01768	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
NEHPIGDC_01769	2.88e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
NEHPIGDC_01770	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
NEHPIGDC_01771	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
NEHPIGDC_01772	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
NEHPIGDC_01773	7.98e-224	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
NEHPIGDC_01774	8.91e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NEHPIGDC_01775	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
NEHPIGDC_01776	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NEHPIGDC_01777	3.39e-128	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
NEHPIGDC_01778	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NEHPIGDC_01779	3.6e-113	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
NEHPIGDC_01780	6.82e-193	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
NEHPIGDC_01781	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
NEHPIGDC_01782	1.16e-206	yisR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_01783	1.06e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NEHPIGDC_01784	6.75e-245	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NEHPIGDC_01785	1.72e-120	yisT	-	-	S	-	-	-	DinB family
NEHPIGDC_01786	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
NEHPIGDC_01787	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NEHPIGDC_01788	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
NEHPIGDC_01789	4.53e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEHPIGDC_01790	2.35e-144	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NEHPIGDC_01791	5.36e-293	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
NEHPIGDC_01792	3.87e-184	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
NEHPIGDC_01793	7.74e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
NEHPIGDC_01794	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
NEHPIGDC_01795	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NEHPIGDC_01796	1.82e-181	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NEHPIGDC_01797	2.87e-103	-	-	-	L	-	-	-	Tn3 transposase DDE domain
NEHPIGDC_01798	2.2e-100	-	-	-	-	-	-	-	-
NEHPIGDC_01799	5.09e-42	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_01800	5.92e-194	-	-	-	EG	-	-	-	Spore germination protein
NEHPIGDC_01801	1.07e-84	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
NEHPIGDC_01802	2.67e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NEHPIGDC_01803	9.14e-206	-	-	-	P	-	-	-	Catalase
NEHPIGDC_01804	3.18e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
NEHPIGDC_01805	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEHPIGDC_01806	7.39e-108	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
NEHPIGDC_01807	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
NEHPIGDC_01808	4.34e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NEHPIGDC_01809	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
NEHPIGDC_01810	7.99e-193	-	-	-	S	-	-	-	membrane
NEHPIGDC_01811	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEHPIGDC_01812	0.0	-	-	-	I	-	-	-	PLD-like domain
NEHPIGDC_01813	2.31e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEHPIGDC_01814	4.1e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_01815	1.57e-197	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_01816	1.64e-88	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_01817	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NEHPIGDC_01818	4.29e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
NEHPIGDC_01819	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
NEHPIGDC_01820	4.16e-122	-	-	-	-	-	-	-	-
NEHPIGDC_01821	9.6e-217	-	-	-	-	-	-	-	-
NEHPIGDC_01822	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
NEHPIGDC_01823	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NEHPIGDC_01824	7.44e-121	-	-	-	-	-	-	-	-
NEHPIGDC_01825	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
NEHPIGDC_01826	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
NEHPIGDC_01827	1.07e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01828	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NEHPIGDC_01829	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
NEHPIGDC_01830	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
NEHPIGDC_01831	1.92e-08	-	-	-	-	-	-	-	-
NEHPIGDC_01832	2.16e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NEHPIGDC_01833	8.38e-184	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NEHPIGDC_01834	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
NEHPIGDC_01835	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
NEHPIGDC_01836	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
NEHPIGDC_01837	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
NEHPIGDC_01838	2.89e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEHPIGDC_01839	1.01e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEHPIGDC_01840	7.35e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NEHPIGDC_01841	8.03e-277	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
NEHPIGDC_01842	2.33e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NEHPIGDC_01843	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
NEHPIGDC_01844	3.51e-224	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEHPIGDC_01845	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
NEHPIGDC_01846	1.53e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NEHPIGDC_01847	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
NEHPIGDC_01848	1.23e-130	yjaV	-	-	-	-	-	-	-
NEHPIGDC_01849	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
NEHPIGDC_01850	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
NEHPIGDC_01851	2.67e-38	yjzB	-	-	-	-	-	-	-
NEHPIGDC_01852	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEHPIGDC_01853	1.25e-301	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEHPIGDC_01854	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
NEHPIGDC_01855	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_01856	3.43e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_01857	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NEHPIGDC_01858	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_01859	1.03e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_01860	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
NEHPIGDC_01861	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
NEHPIGDC_01862	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NEHPIGDC_01863	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_01864	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_01865	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_01866	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_01867	7.88e-259	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEHPIGDC_01868	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_01869	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEHPIGDC_01870	2.03e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
NEHPIGDC_01871	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NEHPIGDC_01872	3.6e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NEHPIGDC_01873	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NEHPIGDC_01874	2.68e-28	-	-	-	-	-	-	-	-
NEHPIGDC_01876	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
NEHPIGDC_01877	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
NEHPIGDC_01878	4.17e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NEHPIGDC_01879	1.21e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_01880	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
NEHPIGDC_01881	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
NEHPIGDC_01882	3.43e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEHPIGDC_01883	2.58e-203	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NEHPIGDC_01884	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NEHPIGDC_01885	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEHPIGDC_01886	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NEHPIGDC_01887	3.16e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
NEHPIGDC_01888	3e-273	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
NEHPIGDC_01889	1.8e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
NEHPIGDC_01890	2.76e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEHPIGDC_01891	2.52e-237	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NEHPIGDC_01892	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEHPIGDC_01893	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NEHPIGDC_01894	8.5e-103	yjbX	-	-	S	-	-	-	Spore coat protein
NEHPIGDC_01895	4.76e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
NEHPIGDC_01896	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
NEHPIGDC_01897	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
NEHPIGDC_01898	2.34e-51	cotW	-	-	-	ko:K06341	-	ko00000	-
NEHPIGDC_01899	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
NEHPIGDC_01900	5.03e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
NEHPIGDC_01903	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
NEHPIGDC_01904	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEHPIGDC_01905	6.31e-51	-	-	-	-	-	-	-	-
NEHPIGDC_01906	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_01907	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
NEHPIGDC_01908	7.77e-177	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
NEHPIGDC_01909	4.65e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NEHPIGDC_01910	7.47e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NEHPIGDC_01911	1.68e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
NEHPIGDC_01912	4.27e-273	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
NEHPIGDC_01914	1.24e-14	-	-	-	-	-	-	-	-
NEHPIGDC_01915	1.35e-51	-	-	-	-	-	-	-	-
NEHPIGDC_01916	3.27e-41	-	-	-	-	-	-	-	-
NEHPIGDC_01917	1.3e-311	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
NEHPIGDC_01921	3.06e-158	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NEHPIGDC_01922	7.38e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NEHPIGDC_01923	3.42e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_01924	0.000759	-	-	-	-	-	-	-	-
NEHPIGDC_01925	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
NEHPIGDC_01926	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_01927	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NEHPIGDC_01928	3.93e-77	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
NEHPIGDC_01929	5.12e-117	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NEHPIGDC_01931	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEHPIGDC_01932	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
NEHPIGDC_01933	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
NEHPIGDC_01934	1.52e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NEHPIGDC_01936	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NEHPIGDC_01937	1.5e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
NEHPIGDC_01938	4.62e-29	yjfB	-	-	S	-	-	-	Putative motility protein
NEHPIGDC_01939	6.19e-208	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
NEHPIGDC_01940	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
NEHPIGDC_01941	1.22e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
NEHPIGDC_01942	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
NEHPIGDC_01943	6.51e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NEHPIGDC_01945	9.09e-148	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NEHPIGDC_01947	6.72e-286	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NEHPIGDC_01948	2.06e-278	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NEHPIGDC_01949	1.11e-41	-	-	-	-	-	-	-	-
NEHPIGDC_01950	3.25e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NEHPIGDC_01951	5.23e-155	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
NEHPIGDC_01952	3.81e-173	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NEHPIGDC_01953	6.04e-223	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
NEHPIGDC_01954	5.79e-117	yjlB	-	-	S	-	-	-	Cupin domain
NEHPIGDC_01955	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NEHPIGDC_01956	3.56e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NEHPIGDC_01957	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NEHPIGDC_01958	6.16e-314	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
NEHPIGDC_01959	4.57e-245	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
NEHPIGDC_01960	3.61e-243	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NEHPIGDC_01961	2.18e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NEHPIGDC_01962	5.24e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_01963	5.58e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
NEHPIGDC_01964	2.32e-236	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NEHPIGDC_01965	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
NEHPIGDC_01966	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NEHPIGDC_01967	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEHPIGDC_01968	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
NEHPIGDC_01969	4.79e-311	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
NEHPIGDC_01970	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NEHPIGDC_01972	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
NEHPIGDC_01973	2.27e-219	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NEHPIGDC_01974	1.11e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
NEHPIGDC_01975	5.99e-143	yjqB	-	-	S	-	-	-	Pfam:DUF867
NEHPIGDC_01976	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
NEHPIGDC_01977	1.79e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
NEHPIGDC_01978	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEHPIGDC_01980	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
NEHPIGDC_01981	3.55e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
NEHPIGDC_01985	7.48e-106	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NEHPIGDC_01986	3.93e-178	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
NEHPIGDC_01987	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
NEHPIGDC_01988	0.0	yqbA	-	-	S	-	-	-	portal protein
NEHPIGDC_01989	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
NEHPIGDC_01990	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
NEHPIGDC_01991	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
NEHPIGDC_01992	1.23e-84	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
NEHPIGDC_01993	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NEHPIGDC_01994	4.77e-100	xkdJ	-	-	-	-	-	-	-
NEHPIGDC_01995	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
NEHPIGDC_01996	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
NEHPIGDC_01997	3.34e-101	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
NEHPIGDC_01998	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
NEHPIGDC_01999	1.77e-158	xkdP	-	-	S	-	-	-	Lysin motif
NEHPIGDC_02000	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
NEHPIGDC_02001	1.24e-52	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
NEHPIGDC_02002	1.33e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
NEHPIGDC_02003	4.2e-242	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NEHPIGDC_02004	6.51e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
NEHPIGDC_02005	8.94e-56	-	-	-	-	-	-	-	-
NEHPIGDC_02006	0.0	-	-	-	-	-	-	-	-
NEHPIGDC_02007	5.22e-59	xkdW	-	-	S	-	-	-	XkdW protein
NEHPIGDC_02008	4.47e-31	xkdX	-	-	-	-	-	-	-
NEHPIGDC_02009	2.81e-194	xepA	-	-	-	-	-	-	-
NEHPIGDC_02010	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
NEHPIGDC_02011	3.87e-51	xhlB	-	-	S	-	-	-	SPP1 phage holin
NEHPIGDC_02012	1.85e-208	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_02014	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
NEHPIGDC_02015	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
NEHPIGDC_02016	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NEHPIGDC_02017	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
NEHPIGDC_02018	1.09e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NEHPIGDC_02019	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NEHPIGDC_02021	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEHPIGDC_02022	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_02024	6.72e-288	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NEHPIGDC_02025	9.98e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
NEHPIGDC_02026	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
NEHPIGDC_02027	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_02028	2.03e-222	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NEHPIGDC_02029	5.25e-234	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_02030	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NEHPIGDC_02032	1e-226	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
NEHPIGDC_02033	1.14e-255	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NEHPIGDC_02034	5.11e-210	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NEHPIGDC_02035	1.63e-234	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEHPIGDC_02036	1.34e-259	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
NEHPIGDC_02037	2.53e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
NEHPIGDC_02038	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
NEHPIGDC_02039	5.35e-289	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NEHPIGDC_02040	7.15e-14	-	-	-	-	-	-	-	-
NEHPIGDC_02041	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEHPIGDC_02042	1.57e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
NEHPIGDC_02043	3.59e-128	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEHPIGDC_02044	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NEHPIGDC_02045	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NEHPIGDC_02046	2.76e-216	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NEHPIGDC_02047	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEHPIGDC_02048	1.6e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEHPIGDC_02049	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
NEHPIGDC_02050	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
NEHPIGDC_02051	1.35e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
NEHPIGDC_02053	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
NEHPIGDC_02054	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEHPIGDC_02055	3.51e-224	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NEHPIGDC_02056	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEHPIGDC_02057	2.2e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NEHPIGDC_02058	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_02059	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NEHPIGDC_02060	2.97e-143	ykoF	-	-	S	-	-	-	YKOF-related Family
NEHPIGDC_02061	3.03e-159	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_02062	1.42e-305	ykoH	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_02063	2.26e-144	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NEHPIGDC_02064	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NEHPIGDC_02065	1.45e-08	-	-	-	-	-	-	-	-
NEHPIGDC_02067	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NEHPIGDC_02068	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
NEHPIGDC_02069	6.67e-25	-	-	-	-	-	-	-	-
NEHPIGDC_02070	2.07e-34	ykoL	-	-	-	-	-	-	-
NEHPIGDC_02071	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
NEHPIGDC_02072	1.33e-278	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NEHPIGDC_02073	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
NEHPIGDC_02074	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NEHPIGDC_02075	0.0	ykoS	-	-	-	-	-	-	-
NEHPIGDC_02076	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_02077	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
NEHPIGDC_02078	7.55e-206	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NEHPIGDC_02079	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
NEHPIGDC_02080	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
NEHPIGDC_02081	3.39e-179	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NEHPIGDC_02082	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_02083	2.21e-203	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
NEHPIGDC_02084	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
NEHPIGDC_02085	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
NEHPIGDC_02086	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NEHPIGDC_02087	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
NEHPIGDC_02089	2.51e-28	ykzE	-	-	-	-	-	-	-
NEHPIGDC_02090	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
NEHPIGDC_02091	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_02092	1.53e-112	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEHPIGDC_02094	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NEHPIGDC_02095	2.47e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NEHPIGDC_02096	1.99e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NEHPIGDC_02097	3.25e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEHPIGDC_02098	1.61e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NEHPIGDC_02099	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NEHPIGDC_02100	5.28e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NEHPIGDC_02101	5.03e-122	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NEHPIGDC_02102	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NEHPIGDC_02104	5.84e-95	eag	-	-	-	-	-	-	-
NEHPIGDC_02105	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NEHPIGDC_02106	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
NEHPIGDC_02107	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
NEHPIGDC_02108	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
NEHPIGDC_02109	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NEHPIGDC_02110	6.76e-227	ykvI	-	-	S	-	-	-	membrane
NEHPIGDC_02111	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NEHPIGDC_02112	5.72e-104	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
NEHPIGDC_02113	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NEHPIGDC_02114	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NEHPIGDC_02115	1.73e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEHPIGDC_02116	2.2e-171	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_02117	2.12e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
NEHPIGDC_02118	7.56e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
NEHPIGDC_02119	2.41e-68	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
NEHPIGDC_02120	6.29e-122	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
NEHPIGDC_02121	2.2e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
NEHPIGDC_02122	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02123	2.6e-39	-	-	-	-	-	-	-	-
NEHPIGDC_02124	3.7e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
NEHPIGDC_02125	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_02126	2.76e-115	stoA	-	-	CO	-	-	-	thiol-disulfide
NEHPIGDC_02127	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NEHPIGDC_02128	3.99e-09	-	-	-	-	-	-	-	-
NEHPIGDC_02129	2.34e-265	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NEHPIGDC_02130	7.72e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02132	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
NEHPIGDC_02133	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_02134	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
NEHPIGDC_02135	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEHPIGDC_02136	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02137	1.44e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
NEHPIGDC_02138	2.04e-72	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_02139	1.1e-68	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_02140	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_02141	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NEHPIGDC_02142	1.68e-17	vgb	-	-	H	ko:K18235	-	ko00000,ko01000,ko01504	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
NEHPIGDC_02143	5.14e-170	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
NEHPIGDC_02144	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NEHPIGDC_02145	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_02146	8.45e-283	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEHPIGDC_02147	1.05e-22	-	-	-	-	-	-	-	-
NEHPIGDC_02148	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
NEHPIGDC_02149	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
NEHPIGDC_02150	3.62e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_02151	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02152	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
NEHPIGDC_02153	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_02154	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
NEHPIGDC_02155	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02156	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
NEHPIGDC_02157	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
NEHPIGDC_02158	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
NEHPIGDC_02159	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02160	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
NEHPIGDC_02161	2.21e-225	ykuO	-	-	-	-	-	-	-
NEHPIGDC_02162	1.3e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NEHPIGDC_02163	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEHPIGDC_02164	7.99e-276	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEHPIGDC_02165	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
NEHPIGDC_02166	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
NEHPIGDC_02167	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
NEHPIGDC_02168	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
NEHPIGDC_02169	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
NEHPIGDC_02170	9.9e-200	yknT	-	-	-	ko:K06437	-	ko00000	-
NEHPIGDC_02171	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NEHPIGDC_02172	5.12e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NEHPIGDC_02173	4.29e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
NEHPIGDC_02174	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NEHPIGDC_02175	9.03e-108	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
NEHPIGDC_02176	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NEHPIGDC_02177	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NEHPIGDC_02178	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NEHPIGDC_02179	1.6e-151	yknW	-	-	S	-	-	-	Yip1 domain
NEHPIGDC_02180	1.57e-231	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEHPIGDC_02181	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_02182	2.1e-269	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NEHPIGDC_02183	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02184	8.21e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
NEHPIGDC_02185	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NEHPIGDC_02186	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEHPIGDC_02187	5.43e-52	ykoA	-	-	-	-	-	-	-
NEHPIGDC_02188	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEHPIGDC_02189	2.86e-215	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHPIGDC_02190	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NEHPIGDC_02191	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
NEHPIGDC_02192	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
NEHPIGDC_02193	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
NEHPIGDC_02194	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NEHPIGDC_02195	9.41e-196	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
NEHPIGDC_02196	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NEHPIGDC_02197	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NEHPIGDC_02198	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHPIGDC_02199	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NEHPIGDC_02200	2.03e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
NEHPIGDC_02201	1.61e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEHPIGDC_02202	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NEHPIGDC_02203	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
NEHPIGDC_02204	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEHPIGDC_02205	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEHPIGDC_02206	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEHPIGDC_02207	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEHPIGDC_02208	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
NEHPIGDC_02209	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
NEHPIGDC_02210	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NEHPIGDC_02211	8.77e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NEHPIGDC_02212	2.03e-35	ykzI	-	-	-	-	-	-	-
NEHPIGDC_02213	2.72e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
NEHPIGDC_02214	4.07e-98	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
NEHPIGDC_02215	8.61e-222	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NEHPIGDC_02216	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
NEHPIGDC_02217	0.0	ylaA	-	-	-	-	-	-	-
NEHPIGDC_02218	1.44e-56	ylaB	-	-	-	-	-	-	-
NEHPIGDC_02219	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_02221	5.7e-56	ylaE	-	-	-	-	-	-	-
NEHPIGDC_02222	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
NEHPIGDC_02223	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NEHPIGDC_02224	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
NEHPIGDC_02225	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02226	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEHPIGDC_02227	4.04e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
NEHPIGDC_02228	1.55e-110	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NEHPIGDC_02229	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NEHPIGDC_02230	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
NEHPIGDC_02231	2.11e-272	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NEHPIGDC_02232	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NEHPIGDC_02233	2e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NEHPIGDC_02234	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NEHPIGDC_02235	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NEHPIGDC_02236	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NEHPIGDC_02237	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NEHPIGDC_02238	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NEHPIGDC_02239	1.21e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
NEHPIGDC_02240	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
NEHPIGDC_02241	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
NEHPIGDC_02242	4.58e-258	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
NEHPIGDC_02243	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
NEHPIGDC_02244	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
NEHPIGDC_02245	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
NEHPIGDC_02246	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
NEHPIGDC_02247	6.07e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
NEHPIGDC_02248	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEHPIGDC_02249	5.5e-282	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
NEHPIGDC_02250	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NEHPIGDC_02251	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NEHPIGDC_02252	2.22e-296	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NEHPIGDC_02254	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
NEHPIGDC_02255	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NEHPIGDC_02256	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NEHPIGDC_02257	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
NEHPIGDC_02258	9.23e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEHPIGDC_02259	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NEHPIGDC_02260	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NEHPIGDC_02261	4.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEHPIGDC_02262	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
NEHPIGDC_02263	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NEHPIGDC_02264	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
NEHPIGDC_02265	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEHPIGDC_02266	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEHPIGDC_02267	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEHPIGDC_02268	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NEHPIGDC_02269	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEHPIGDC_02270	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
NEHPIGDC_02271	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEHPIGDC_02272	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02273	7.41e-151	ylxX	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02274	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
NEHPIGDC_02275	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEHPIGDC_02276	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEHPIGDC_02277	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
NEHPIGDC_02278	1.06e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NEHPIGDC_02279	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_02280	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_02281	1.57e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NEHPIGDC_02282	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
NEHPIGDC_02283	1.46e-50	ylmC	-	-	S	-	-	-	sporulation protein
NEHPIGDC_02284	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
NEHPIGDC_02285	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEHPIGDC_02286	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEHPIGDC_02287	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
NEHPIGDC_02288	1.49e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
NEHPIGDC_02289	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
NEHPIGDC_02290	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEHPIGDC_02291	1.58e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
NEHPIGDC_02292	1.57e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEHPIGDC_02293	2.9e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEHPIGDC_02294	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEHPIGDC_02295	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
NEHPIGDC_02296	2.54e-214	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NEHPIGDC_02297	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEHPIGDC_02298	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NEHPIGDC_02299	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
NEHPIGDC_02300	3.03e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NEHPIGDC_02301	3.65e-222	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEHPIGDC_02302	3.8e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEHPIGDC_02303	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEHPIGDC_02305	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
NEHPIGDC_02306	1.04e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
NEHPIGDC_02307	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
NEHPIGDC_02308	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NEHPIGDC_02309	2.06e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NEHPIGDC_02310	1.45e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
NEHPIGDC_02311	2.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
NEHPIGDC_02312	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
NEHPIGDC_02313	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
NEHPIGDC_02314	2.81e-200	yloC	-	-	S	-	-	-	stress-induced protein
NEHPIGDC_02315	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
NEHPIGDC_02316	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NEHPIGDC_02317	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEHPIGDC_02318	7.28e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEHPIGDC_02319	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEHPIGDC_02320	1.38e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEHPIGDC_02321	1.74e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEHPIGDC_02322	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEHPIGDC_02323	7.53e-264	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEHPIGDC_02324	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NEHPIGDC_02325	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NEHPIGDC_02326	3.92e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEHPIGDC_02327	1.34e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NEHPIGDC_02328	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NEHPIGDC_02329	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NEHPIGDC_02330	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02331	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
NEHPIGDC_02332	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NEHPIGDC_02333	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NEHPIGDC_02334	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEHPIGDC_02335	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NEHPIGDC_02336	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEHPIGDC_02337	1.86e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NEHPIGDC_02338	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NEHPIGDC_02339	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEHPIGDC_02340	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEHPIGDC_02341	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NEHPIGDC_02342	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEHPIGDC_02343	1.67e-114	-	-	-	-	-	-	-	-
NEHPIGDC_02344	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEHPIGDC_02345	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEHPIGDC_02346	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NEHPIGDC_02347	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NEHPIGDC_02348	9.77e-80	ylqD	-	-	S	-	-	-	YlqD protein
NEHPIGDC_02349	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEHPIGDC_02350	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NEHPIGDC_02351	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEHPIGDC_02352	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEHPIGDC_02353	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHPIGDC_02354	0.0	ylqG	-	-	-	-	-	-	-
NEHPIGDC_02355	1.4e-58	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
NEHPIGDC_02356	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEHPIGDC_02357	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEHPIGDC_02358	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
NEHPIGDC_02359	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEHPIGDC_02360	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NEHPIGDC_02361	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
NEHPIGDC_02362	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NEHPIGDC_02363	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NEHPIGDC_02364	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NEHPIGDC_02365	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NEHPIGDC_02366	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
NEHPIGDC_02367	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
NEHPIGDC_02368	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
NEHPIGDC_02369	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NEHPIGDC_02370	2.34e-145	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
NEHPIGDC_02371	1.22e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NEHPIGDC_02372	7.27e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
NEHPIGDC_02373	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
NEHPIGDC_02374	1.28e-311	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
NEHPIGDC_02375	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
NEHPIGDC_02376	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
NEHPIGDC_02377	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
NEHPIGDC_02378	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NEHPIGDC_02379	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NEHPIGDC_02380	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
NEHPIGDC_02381	1.12e-136	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
NEHPIGDC_02382	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
NEHPIGDC_02383	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
NEHPIGDC_02384	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
NEHPIGDC_02385	2.74e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NEHPIGDC_02386	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NEHPIGDC_02387	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
NEHPIGDC_02388	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
NEHPIGDC_02389	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NEHPIGDC_02390	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
NEHPIGDC_02391	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
NEHPIGDC_02392	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NEHPIGDC_02393	1.36e-111	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NEHPIGDC_02394	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_02395	6.62e-99	ylxL	-	-	-	-	-	-	-
NEHPIGDC_02396	2.65e-166	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NEHPIGDC_02397	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEHPIGDC_02398	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NEHPIGDC_02399	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEHPIGDC_02400	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEHPIGDC_02401	1.65e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NEHPIGDC_02402	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEHPIGDC_02403	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NEHPIGDC_02404	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEHPIGDC_02405	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHPIGDC_02406	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NEHPIGDC_02407	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NEHPIGDC_02408	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
NEHPIGDC_02409	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
NEHPIGDC_02410	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEHPIGDC_02411	7.83e-60	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
NEHPIGDC_02412	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEHPIGDC_02413	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEHPIGDC_02414	1.34e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NEHPIGDC_02415	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEHPIGDC_02416	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEHPIGDC_02417	2.06e-232	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
NEHPIGDC_02418	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
NEHPIGDC_02419	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
NEHPIGDC_02420	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
NEHPIGDC_02421	9.94e-142	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NEHPIGDC_02422	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEHPIGDC_02423	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NEHPIGDC_02424	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEHPIGDC_02425	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEHPIGDC_02426	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
NEHPIGDC_02427	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
NEHPIGDC_02428	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NEHPIGDC_02429	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02430	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_02431	4.03e-300	albE	-	-	S	-	-	-	Peptidase M16
NEHPIGDC_02432	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
NEHPIGDC_02433	2.12e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NEHPIGDC_02434	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
NEHPIGDC_02435	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
NEHPIGDC_02436	8.75e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
NEHPIGDC_02437	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEHPIGDC_02438	3.05e-299	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NEHPIGDC_02439	2.72e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEHPIGDC_02440	9.84e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
NEHPIGDC_02441	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NEHPIGDC_02442	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
NEHPIGDC_02443	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
NEHPIGDC_02444	1.44e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NEHPIGDC_02445	2.3e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NEHPIGDC_02446	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEHPIGDC_02447	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
NEHPIGDC_02448	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
NEHPIGDC_02449	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEHPIGDC_02450	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEHPIGDC_02451	1.29e-89	-	-	-	S	-	-	-	Regulatory protein YrvL
NEHPIGDC_02453	2.28e-126	ymcC	-	-	S	-	-	-	Membrane
NEHPIGDC_02454	3.43e-140	pksA	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02455	3.3e-166	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
NEHPIGDC_02457	2.17e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NEHPIGDC_02459	5.71e-237	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
NEHPIGDC_02460	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
NEHPIGDC_02461	9.09e-50	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
NEHPIGDC_02462	4.36e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEHPIGDC_02463	6.55e-312	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
NEHPIGDC_02464	8.31e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
NEHPIGDC_02465	4.29e-174	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
NEHPIGDC_02466	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NEHPIGDC_02467	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
NEHPIGDC_02468	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NEHPIGDC_02469	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
NEHPIGDC_02470	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
NEHPIGDC_02471	8.33e-296	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NEHPIGDC_02472	8.03e-81	ymzB	-	-	-	-	-	-	-
NEHPIGDC_02473	4.61e-208	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NEHPIGDC_02474	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
NEHPIGDC_02475	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
NEHPIGDC_02476	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
NEHPIGDC_02477	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
NEHPIGDC_02478	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NEHPIGDC_02480	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
NEHPIGDC_02481	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEHPIGDC_02482	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NEHPIGDC_02483	9.4e-31	-	-	-	-	-	-	-	-
NEHPIGDC_02484	1.2e-30	ymzA	-	-	-	-	-	-	-
NEHPIGDC_02485	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NEHPIGDC_02486	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPIGDC_02487	1.59e-241	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPIGDC_02488	9.1e-141	-	-	-	-	-	-	-	-
NEHPIGDC_02489	9.94e-151	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_02490	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
NEHPIGDC_02491	6.07e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEHPIGDC_02492	1.67e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NEHPIGDC_02493	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
NEHPIGDC_02494	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEHPIGDC_02495	6.21e-13	-	-	-	-	-	-	-	-
NEHPIGDC_02497	1.04e-78	-	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
NEHPIGDC_02498	9.6e-120	-	-	-	M	-	-	-	Glycosyltransferase like family
NEHPIGDC_02499	1.17e-155	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
NEHPIGDC_02500	6.07e-248	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
NEHPIGDC_02501	3.11e-270	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
NEHPIGDC_02503	3.38e-125	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NEHPIGDC_02504	5.66e-94	-	-	-	S	-	-	-	CAAX protease self-immunity
NEHPIGDC_02506	3.39e-31	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
NEHPIGDC_02507	3.14e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
NEHPIGDC_02510	1.76e-109	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
NEHPIGDC_02511	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
NEHPIGDC_02512	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NEHPIGDC_02513	8.66e-276	xylR	-	-	GK	-	-	-	ROK family
NEHPIGDC_02514	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NEHPIGDC_02515	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
NEHPIGDC_02516	2.51e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
NEHPIGDC_02517	2.01e-310	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEHPIGDC_02518	1.77e-280	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEHPIGDC_02519	1.91e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
NEHPIGDC_02520	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
NEHPIGDC_02521	7.54e-22	-	-	-	-	-	-	-	-
NEHPIGDC_02524	3.91e-210	-	-	-	S	-	-	-	Thymidylate synthase
NEHPIGDC_02525	2.08e-163	-	-	-	S	-	-	-	Domain of unknown function, YrpD
NEHPIGDC_02528	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
NEHPIGDC_02529	8.92e-96	-	-	-	-	-	-	-	-
NEHPIGDC_02530	2.12e-102	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
NEHPIGDC_02533	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
NEHPIGDC_02534	1.79e-246	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
NEHPIGDC_02535	1.47e-284	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
NEHPIGDC_02536	1.7e-194	yndG	-	-	S	-	-	-	DoxX-like family
NEHPIGDC_02537	6.98e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
NEHPIGDC_02538	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
NEHPIGDC_02540	1.88e-174	yndL	-	-	S	-	-	-	Replication protein
NEHPIGDC_02541	3.79e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NEHPIGDC_02542	1.22e-101	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NEHPIGDC_02543	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEHPIGDC_02544	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NEHPIGDC_02545	3.97e-145	yneB	-	-	L	-	-	-	resolvase
NEHPIGDC_02546	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
NEHPIGDC_02547	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NEHPIGDC_02548	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
NEHPIGDC_02549	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NEHPIGDC_02550	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
NEHPIGDC_02551	1.68e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
NEHPIGDC_02552	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
NEHPIGDC_02553	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
NEHPIGDC_02554	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
NEHPIGDC_02555	4.75e-84	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
NEHPIGDC_02556	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
NEHPIGDC_02557	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
NEHPIGDC_02558	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEHPIGDC_02559	3.74e-120	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NEHPIGDC_02560	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
NEHPIGDC_02562	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
NEHPIGDC_02563	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
NEHPIGDC_02564	5.48e-70	yneQ	-	-	-	-	-	-	-
NEHPIGDC_02565	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NEHPIGDC_02566	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEHPIGDC_02567	2.85e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
NEHPIGDC_02568	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHPIGDC_02569	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEHPIGDC_02570	1.82e-18	-	-	-	-	-	-	-	-
NEHPIGDC_02571	2.5e-74	ynfC	-	-	-	-	-	-	-
NEHPIGDC_02572	9.17e-303	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
NEHPIGDC_02573	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
NEHPIGDC_02575	2.36e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
NEHPIGDC_02576	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NEHPIGDC_02577	2.45e-103	yngA	-	-	S	-	-	-	membrane
NEHPIGDC_02578	1.07e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NEHPIGDC_02579	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
NEHPIGDC_02580	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
NEHPIGDC_02581	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NEHPIGDC_02582	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
NEHPIGDC_02583	1.59e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
NEHPIGDC_02584	1.19e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
NEHPIGDC_02585	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
NEHPIGDC_02586	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NEHPIGDC_02587	3.76e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NEHPIGDC_02588	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
NEHPIGDC_02589	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
NEHPIGDC_02590	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
NEHPIGDC_02591	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_02592	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_02593	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NEHPIGDC_02594	1.72e-243	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NEHPIGDC_02595	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
NEHPIGDC_02596	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
NEHPIGDC_02598	6.59e-124	-	-	-	L	-	-	-	Integrase
NEHPIGDC_02599	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
NEHPIGDC_02600	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
NEHPIGDC_02601	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02602	3.43e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NEHPIGDC_02603	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NEHPIGDC_02604	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
NEHPIGDC_02605	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02606	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEHPIGDC_02607	6.41e-184	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEHPIGDC_02608	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NEHPIGDC_02609	2.28e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_02610	1.1e-50	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
NEHPIGDC_02611	6.36e-144	yoxB	-	-	-	-	-	-	-
NEHPIGDC_02612	2.81e-123	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NEHPIGDC_02613	1.39e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEHPIGDC_02614	1.25e-121	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NEHPIGDC_02615	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NEHPIGDC_02616	6.7e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_02617	6.14e-298	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
NEHPIGDC_02618	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NEHPIGDC_02619	1.37e-233	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPIGDC_02620	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHPIGDC_02621	3.44e-43	yoaF	-	-	-	-	-	-	-
NEHPIGDC_02623	1.2e-18	-	-	-	-	-	-	-	-
NEHPIGDC_02624	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
NEHPIGDC_02625	7.22e-314	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
NEHPIGDC_02626	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
NEHPIGDC_02627	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
NEHPIGDC_02628	1.21e-143	yoaK	-	-	S	-	-	-	Membrane
NEHPIGDC_02629	5e-253	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
NEHPIGDC_02630	5.08e-171	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NEHPIGDC_02633	1.54e-293	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
NEHPIGDC_02636	7.48e-185	yoaP	-	-	K	-	-	-	YoaP-like
NEHPIGDC_02637	3.01e-87	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
NEHPIGDC_02639	3.92e-115	-	-	-	-	-	-	-	-
NEHPIGDC_02640	3.63e-218	yoaR	-	-	V	-	-	-	vancomycin resistance protein
NEHPIGDC_02641	6.5e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NEHPIGDC_02642	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_02643	4.62e-83	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
NEHPIGDC_02644	7.56e-115	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
NEHPIGDC_02647	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
NEHPIGDC_02648	1.07e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
NEHPIGDC_02649	2.11e-49	-	-	-	S	-	-	-	TM2 domain
NEHPIGDC_02650	2.6e-11	-	-	-	K	-	-	-	Helix-turn-helix
NEHPIGDC_02652	1.54e-84	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
NEHPIGDC_02653	1.67e-29	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NEHPIGDC_02654	2.71e-29	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHPIGDC_02655	2.59e-220	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
NEHPIGDC_02656	3.14e-167	-	-	-	K	-	-	-	Bacterial regulatory proteins, lacI family
NEHPIGDC_02657	1.23e-272	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NEHPIGDC_02659	1.86e-53	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEHPIGDC_02660	2.16e-128	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NEHPIGDC_02661	1.33e-141	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_02662	0.0	aga	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha-galactosidase
NEHPIGDC_02663	3.61e-133	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NEHPIGDC_02664	2.24e-110	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
NEHPIGDC_02665	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NEHPIGDC_02666	4.64e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
NEHPIGDC_02667	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
NEHPIGDC_02668	1.82e-71	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
NEHPIGDC_02669	6.36e-172	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NEHPIGDC_02670	4.16e-180	-	-	-	J	-	-	-	FR47-like protein
NEHPIGDC_02671	4.91e-124	yobS	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02672	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NEHPIGDC_02673	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NEHPIGDC_02674	2.3e-226	yobV	-	-	K	-	-	-	WYL domain
NEHPIGDC_02675	3.01e-120	yobW	-	-	-	-	-	-	-
NEHPIGDC_02676	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
NEHPIGDC_02677	2.89e-151	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NEHPIGDC_02678	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
NEHPIGDC_02679	2.6e-185	-	-	-	-	-	-	-	-
NEHPIGDC_02680	1.8e-120	yocC	-	-	-	-	-	-	-
NEHPIGDC_02681	3.88e-240	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
NEHPIGDC_02682	3.28e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
NEHPIGDC_02683	3.51e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_02684	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_02685	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
NEHPIGDC_02686	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEHPIGDC_02687	8.45e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NEHPIGDC_02688	4.07e-107	yocK	-	-	T	-	-	-	general stress protein
NEHPIGDC_02689	3.02e-70	yocL	-	-	-	-	-	-	-
NEHPIGDC_02690	7.29e-46	-	-	-	-	-	-	-	-
NEHPIGDC_02691	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NEHPIGDC_02692	2.94e-55	yozN	-	-	-	-	-	-	-
NEHPIGDC_02693	1.83e-49	yocN	-	-	-	-	-	-	-
NEHPIGDC_02694	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
NEHPIGDC_02695	1.91e-42	yozC	-	-	-	-	-	-	-
NEHPIGDC_02696	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NEHPIGDC_02697	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
NEHPIGDC_02698	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
NEHPIGDC_02699	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NEHPIGDC_02700	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
NEHPIGDC_02701	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NEHPIGDC_02702	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NEHPIGDC_02703	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
NEHPIGDC_02704	1.33e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
NEHPIGDC_02705	6.01e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NEHPIGDC_02706	2.15e-266	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NEHPIGDC_02707	1.13e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
NEHPIGDC_02708	4.31e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEHPIGDC_02710	1.02e-313	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
NEHPIGDC_02711	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEHPIGDC_02712	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
NEHPIGDC_02713	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
NEHPIGDC_02714	1.85e-58	-	-	-	-	-	-	-	-
NEHPIGDC_02715	1.92e-206	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
NEHPIGDC_02716	3.03e-106	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
NEHPIGDC_02717	1.95e-14	-	-	-	-	-	-	-	-
NEHPIGDC_02718	6.98e-46	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NEHPIGDC_02719	7.66e-201	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NEHPIGDC_02720	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
NEHPIGDC_02721	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
NEHPIGDC_02722	1.11e-139	yodC	-	-	C	-	-	-	nitroreductase
NEHPIGDC_02723	2.17e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
NEHPIGDC_02724	1.61e-221	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NEHPIGDC_02725	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
NEHPIGDC_02726	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPIGDC_02727	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NEHPIGDC_02728	8.7e-166	yodH	-	-	Q	-	-	-	Methyltransferase
NEHPIGDC_02729	2.93e-42	yodI	-	-	-	-	-	-	-
NEHPIGDC_02730	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NEHPIGDC_02731	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NEHPIGDC_02732	2.08e-12	-	-	-	-	-	-	-	-
NEHPIGDC_02733	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
NEHPIGDC_02734	4.69e-137	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
NEHPIGDC_02735	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
NEHPIGDC_02737	7.44e-159	yodN	-	-	-	-	-	-	-
NEHPIGDC_02738	8.55e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NEHPIGDC_02739	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
NEHPIGDC_02740	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
NEHPIGDC_02741	1.51e-196	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
NEHPIGDC_02742	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
NEHPIGDC_02743	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NEHPIGDC_02744	1.14e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NEHPIGDC_02745	0.0	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEHPIGDC_02746	2.31e-183	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
NEHPIGDC_02747	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
NEHPIGDC_02748	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
NEHPIGDC_02749	5.57e-86	cgeA	-	-	-	ko:K06319	-	ko00000	-
NEHPIGDC_02750	4.7e-237	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
NEHPIGDC_02751	1.39e-280	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
NEHPIGDC_02752	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
NEHPIGDC_02753	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NEHPIGDC_02754	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEHPIGDC_02755	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
NEHPIGDC_02756	9.55e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
NEHPIGDC_02757	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
NEHPIGDC_02758	1.13e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02759	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEHPIGDC_02760	3.23e-139	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NEHPIGDC_02761	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
NEHPIGDC_02762	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NEHPIGDC_02763	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02764	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
NEHPIGDC_02765	1.71e-145	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NEHPIGDC_02766	9.96e-124	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEHPIGDC_02767	1.21e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEHPIGDC_02768	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
NEHPIGDC_02769	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
NEHPIGDC_02770	6.15e-187	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
NEHPIGDC_02771	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
NEHPIGDC_02772	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NEHPIGDC_02773	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
NEHPIGDC_02774	3.3e-138	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NEHPIGDC_02775	3.13e-114	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NEHPIGDC_02776	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEHPIGDC_02778	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NEHPIGDC_02779	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
NEHPIGDC_02780	1.17e-22	degR	-	-	-	-	-	-	-
NEHPIGDC_02781	1.5e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
NEHPIGDC_02782	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
NEHPIGDC_02783	1.59e-173	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
NEHPIGDC_02784	3.27e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NEHPIGDC_02785	3.11e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
NEHPIGDC_02786	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
NEHPIGDC_02787	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
NEHPIGDC_02788	1.08e-11	-	-	-	-	-	-	-	-
NEHPIGDC_02789	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
NEHPIGDC_02790	0.0	ypbR	-	-	S	-	-	-	Dynamin family
NEHPIGDC_02791	4.73e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
NEHPIGDC_02792	2.63e-265	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
NEHPIGDC_02793	1.28e-293	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
NEHPIGDC_02794	8.16e-129	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEHPIGDC_02795	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NEHPIGDC_02796	1.17e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NEHPIGDC_02797	1.47e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
NEHPIGDC_02798	2.83e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
NEHPIGDC_02799	1.11e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
NEHPIGDC_02800	2.96e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NEHPIGDC_02801	5.63e-177	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_02802	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
NEHPIGDC_02804	2.72e-284	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NEHPIGDC_02805	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEHPIGDC_02806	3.41e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NEHPIGDC_02807	4e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
NEHPIGDC_02808	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NEHPIGDC_02809	2.13e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
NEHPIGDC_02810	4.33e-95	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NEHPIGDC_02811	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
NEHPIGDC_02812	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
NEHPIGDC_02813	7.14e-11	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
NEHPIGDC_02816	3.44e-236	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
NEHPIGDC_02817	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEHPIGDC_02818	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NEHPIGDC_02819	1.43e-121	ypoC	-	-	-	-	-	-	-
NEHPIGDC_02820	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEHPIGDC_02821	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
NEHPIGDC_02822	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
NEHPIGDC_02823	1.25e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
NEHPIGDC_02824	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02825	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
NEHPIGDC_02826	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NEHPIGDC_02827	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NEHPIGDC_02828	5.47e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NEHPIGDC_02829	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NEHPIGDC_02830	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEHPIGDC_02831	3.04e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEHPIGDC_02832	4.94e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
NEHPIGDC_02833	1.82e-164	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
NEHPIGDC_02834	4.19e-92	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
NEHPIGDC_02835	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEHPIGDC_02836	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
NEHPIGDC_02837	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NEHPIGDC_02838	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
NEHPIGDC_02839	2.82e-126	ypjA	-	-	S	-	-	-	membrane
NEHPIGDC_02840	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
NEHPIGDC_02841	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
NEHPIGDC_02842	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
NEHPIGDC_02843	3.75e-98	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
NEHPIGDC_02844	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
NEHPIGDC_02845	8.74e-298	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
NEHPIGDC_02846	1.35e-299	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEHPIGDC_02847	1.71e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NEHPIGDC_02848	4.5e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEHPIGDC_02849	5.43e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEHPIGDC_02850	3.8e-294	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEHPIGDC_02851	2.71e-151	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
NEHPIGDC_02852	1.2e-144	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NEHPIGDC_02853	8.28e-228	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEHPIGDC_02854	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEHPIGDC_02855	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NEHPIGDC_02856	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEHPIGDC_02857	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEHPIGDC_02858	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
NEHPIGDC_02859	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NEHPIGDC_02860	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NEHPIGDC_02861	1.34e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEHPIGDC_02862	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NEHPIGDC_02863	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NEHPIGDC_02864	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NEHPIGDC_02865	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEHPIGDC_02866	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NEHPIGDC_02867	9.07e-178	yphF	-	-	-	-	-	-	-
NEHPIGDC_02868	3.51e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
NEHPIGDC_02869	9.24e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NEHPIGDC_02870	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NEHPIGDC_02871	8.69e-40	ypzH	-	-	-	-	-	-	-
NEHPIGDC_02872	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
NEHPIGDC_02873	3.18e-133	yphA	-	-	-	-	-	-	-
NEHPIGDC_02874	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
NEHPIGDC_02875	1.98e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEHPIGDC_02876	3.17e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NEHPIGDC_02877	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NEHPIGDC_02878	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
NEHPIGDC_02879	9.34e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
NEHPIGDC_02880	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
NEHPIGDC_02881	1.4e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
NEHPIGDC_02882	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
NEHPIGDC_02883	6.04e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
NEHPIGDC_02884	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NEHPIGDC_02885	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NEHPIGDC_02886	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NEHPIGDC_02887	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
NEHPIGDC_02888	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
NEHPIGDC_02889	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
NEHPIGDC_02890	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEHPIGDC_02891	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
NEHPIGDC_02892	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
NEHPIGDC_02893	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEHPIGDC_02894	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEHPIGDC_02895	1.67e-174	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEHPIGDC_02896	1.49e-254	rsiX	-	-	-	-	-	-	-
NEHPIGDC_02897	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_02898	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_02899	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_02900	1.34e-278	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NEHPIGDC_02901	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
NEHPIGDC_02902	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NEHPIGDC_02903	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NEHPIGDC_02904	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
NEHPIGDC_02905	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
NEHPIGDC_02906	2.28e-270	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NEHPIGDC_02907	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
NEHPIGDC_02908	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEHPIGDC_02909	4.45e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEHPIGDC_02910	2.51e-120	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
NEHPIGDC_02911	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEHPIGDC_02912	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NEHPIGDC_02913	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NEHPIGDC_02914	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NEHPIGDC_02915	4.17e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEHPIGDC_02916	1.41e-70	ypuD	-	-	-	-	-	-	-
NEHPIGDC_02917	1.18e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEHPIGDC_02918	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
NEHPIGDC_02919	8.87e-17	-	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_02921	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEHPIGDC_02922	2.67e-193	ypuA	-	-	S	-	-	-	Secreted protein
NEHPIGDC_02923	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEHPIGDC_02924	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
NEHPIGDC_02925	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NEHPIGDC_02926	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NEHPIGDC_02927	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
NEHPIGDC_02928	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
NEHPIGDC_02929	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
NEHPIGDC_02930	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
NEHPIGDC_02931	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_02932	1.37e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NEHPIGDC_02933	2.47e-75	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
NEHPIGDC_02934	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NEHPIGDC_02935	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NEHPIGDC_02936	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEHPIGDC_02937	3.91e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
NEHPIGDC_02938	4.54e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
NEHPIGDC_02939	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NEHPIGDC_02940	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NEHPIGDC_02941	3.08e-43	yqkK	-	-	-	-	-	-	-
NEHPIGDC_02942	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
NEHPIGDC_02943	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NEHPIGDC_02944	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
NEHPIGDC_02945	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
NEHPIGDC_02946	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_02947	6.16e-282	yqxK	-	-	L	-	-	-	DNA helicase
NEHPIGDC_02948	1.17e-119	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NEHPIGDC_02949	6.19e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
NEHPIGDC_02950	2.09e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
NEHPIGDC_02951	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
NEHPIGDC_02952	1.38e-223	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NEHPIGDC_02953	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
NEHPIGDC_02954	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
NEHPIGDC_02955	1.13e-248	yqkA	-	-	K	-	-	-	GrpB protein
NEHPIGDC_02956	2.25e-78	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
NEHPIGDC_02957	1.29e-111	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
NEHPIGDC_02958	2.66e-65	yqiX	-	-	S	-	-	-	YolD-like protein
NEHPIGDC_02959	4.2e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHPIGDC_02961	2.38e-288	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
NEHPIGDC_02963	1.28e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEHPIGDC_02964	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NEHPIGDC_02965	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
NEHPIGDC_02966	1.62e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEHPIGDC_02967	1.09e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NEHPIGDC_02968	1.13e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEHPIGDC_02969	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
NEHPIGDC_02970	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NEHPIGDC_02971	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEHPIGDC_02972	4.43e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEHPIGDC_02973	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEHPIGDC_02974	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEHPIGDC_02975	6.41e-300	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEHPIGDC_02976	1.77e-32	yqzJ	-	-	-	-	-	-	-
NEHPIGDC_02977	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEHPIGDC_02978	8.77e-184	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
NEHPIGDC_02979	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
NEHPIGDC_02980	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NEHPIGDC_02981	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
NEHPIGDC_02983	3.43e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_02984	8.94e-224	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
NEHPIGDC_02985	7.39e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NEHPIGDC_02986	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NEHPIGDC_02987	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NEHPIGDC_02988	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
NEHPIGDC_02989	1.72e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NEHPIGDC_02990	1.79e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_02991	2.6e-194	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
NEHPIGDC_02992	8.49e-285	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEHPIGDC_02993	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NEHPIGDC_02994	2.24e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NEHPIGDC_02995	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NEHPIGDC_02996	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
NEHPIGDC_02997	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NEHPIGDC_02998	1.74e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
NEHPIGDC_02999	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
NEHPIGDC_03000	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
NEHPIGDC_03001	2.07e-207	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NEHPIGDC_03002	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
NEHPIGDC_03003	1.85e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NEHPIGDC_03004	5.16e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
NEHPIGDC_03005	7.2e-201	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
NEHPIGDC_03006	3.3e-280	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NEHPIGDC_03007	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NEHPIGDC_03008	2.7e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
NEHPIGDC_03009	4.74e-37	-	-	-	-	-	-	-	-
NEHPIGDC_03010	1.9e-271	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NEHPIGDC_03012	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NEHPIGDC_03013	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
NEHPIGDC_03014	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NEHPIGDC_03015	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NEHPIGDC_03016	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
NEHPIGDC_03017	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEHPIGDC_03018	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NEHPIGDC_03019	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHPIGDC_03020	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEHPIGDC_03021	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEHPIGDC_03022	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEHPIGDC_03023	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03024	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NEHPIGDC_03025	1.25e-90	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEHPIGDC_03026	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
NEHPIGDC_03027	8.86e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
NEHPIGDC_03028	2.58e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
NEHPIGDC_03029	6.28e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
NEHPIGDC_03030	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
NEHPIGDC_03031	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
NEHPIGDC_03032	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
NEHPIGDC_03033	1.17e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
NEHPIGDC_03034	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
NEHPIGDC_03035	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEHPIGDC_03036	2.46e-248	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NEHPIGDC_03037	5.55e-100	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
NEHPIGDC_03038	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
NEHPIGDC_03039	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
NEHPIGDC_03040	5.18e-81	yqhP	-	-	-	-	-	-	-
NEHPIGDC_03041	5.75e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NEHPIGDC_03042	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NEHPIGDC_03043	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NEHPIGDC_03044	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
NEHPIGDC_03045	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NEHPIGDC_03046	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NEHPIGDC_03047	5.49e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
NEHPIGDC_03048	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NEHPIGDC_03049	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
NEHPIGDC_03050	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
NEHPIGDC_03051	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
NEHPIGDC_03052	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
NEHPIGDC_03053	7.4e-98	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
NEHPIGDC_03054	1.61e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
NEHPIGDC_03055	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
NEHPIGDC_03056	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
NEHPIGDC_03057	3.24e-58	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
NEHPIGDC_03058	1.18e-45	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
NEHPIGDC_03059	9.89e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
NEHPIGDC_03060	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
NEHPIGDC_03061	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
NEHPIGDC_03062	8.73e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
NEHPIGDC_03063	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NEHPIGDC_03064	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
NEHPIGDC_03065	7.17e-232	yqxL	-	-	P	-	-	-	Mg2 transporter protein
NEHPIGDC_03066	4.95e-306	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NEHPIGDC_03067	1.18e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NEHPIGDC_03069	1.29e-83	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
NEHPIGDC_03070	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
NEHPIGDC_03071	3.2e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
NEHPIGDC_03072	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
NEHPIGDC_03073	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
NEHPIGDC_03074	8.99e-255	yqgU	-	-	-	-	-	-	-
NEHPIGDC_03075	3.04e-283	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
NEHPIGDC_03076	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NEHPIGDC_03077	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NEHPIGDC_03078	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
NEHPIGDC_03079	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
NEHPIGDC_03080	3.38e-14	yqgO	-	-	-	-	-	-	-
NEHPIGDC_03081	3.13e-134	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEHPIGDC_03082	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NEHPIGDC_03083	9e-254	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
NEHPIGDC_03085	3.42e-68	yqzD	-	-	-	-	-	-	-
NEHPIGDC_03086	6.33e-93	yqzC	-	-	S	-	-	-	YceG-like family
NEHPIGDC_03087	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHPIGDC_03088	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEHPIGDC_03089	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NEHPIGDC_03090	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NEHPIGDC_03091	3.71e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NEHPIGDC_03092	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
NEHPIGDC_03093	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
NEHPIGDC_03094	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
NEHPIGDC_03095	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
NEHPIGDC_03096	6.45e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
NEHPIGDC_03097	1.16e-62	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
NEHPIGDC_03098	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEHPIGDC_03099	2.38e-80	yqfX	-	-	S	-	-	-	membrane
NEHPIGDC_03100	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
NEHPIGDC_03101	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
NEHPIGDC_03102	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NEHPIGDC_03103	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
NEHPIGDC_03104	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NEHPIGDC_03105	5.42e-311	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEHPIGDC_03106	4.89e-58	yqfQ	-	-	S	-	-	-	YqfQ-like protein
NEHPIGDC_03107	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEHPIGDC_03108	3.77e-269	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEHPIGDC_03109	6.9e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NEHPIGDC_03110	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
NEHPIGDC_03111	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEHPIGDC_03112	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEHPIGDC_03113	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
NEHPIGDC_03114	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NEHPIGDC_03115	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
NEHPIGDC_03116	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NEHPIGDC_03117	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NEHPIGDC_03118	7.48e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NEHPIGDC_03119	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
NEHPIGDC_03120	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEHPIGDC_03121	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NEHPIGDC_03122	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NEHPIGDC_03123	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEHPIGDC_03124	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
NEHPIGDC_03126	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
NEHPIGDC_03127	2.98e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
NEHPIGDC_03128	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
NEHPIGDC_03129	2.57e-78	yqfB	-	-	-	-	-	-	-
NEHPIGDC_03130	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
NEHPIGDC_03131	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
NEHPIGDC_03132	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
NEHPIGDC_03133	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NEHPIGDC_03134	8.02e-202	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NEHPIGDC_03135	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
NEHPIGDC_03136	9.73e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEHPIGDC_03137	3.26e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
NEHPIGDC_03138	2.8e-256	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEHPIGDC_03139	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NEHPIGDC_03140	2.52e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEHPIGDC_03141	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEHPIGDC_03142	1.68e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NEHPIGDC_03143	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEHPIGDC_03144	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
NEHPIGDC_03145	1.92e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
NEHPIGDC_03146	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NEHPIGDC_03147	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NEHPIGDC_03148	1.93e-242	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NEHPIGDC_03149	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
NEHPIGDC_03150	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NEHPIGDC_03151	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NEHPIGDC_03152	6.65e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
NEHPIGDC_03153	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEHPIGDC_03154	1.39e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
NEHPIGDC_03155	6.61e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEHPIGDC_03156	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NEHPIGDC_03157	4.11e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEHPIGDC_03158	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
NEHPIGDC_03159	8.44e-201	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEHPIGDC_03160	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NEHPIGDC_03161	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
NEHPIGDC_03163	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NEHPIGDC_03164	2.2e-172	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_03165	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_03166	1.26e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
NEHPIGDC_03167	2.69e-170	-	-	-	-	-	-	-	-
NEHPIGDC_03168	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
NEHPIGDC_03169	4.36e-73	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_03170	2.91e-81	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_03171	6.05e-283	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
NEHPIGDC_03172	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
NEHPIGDC_03173	3.69e-223	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
NEHPIGDC_03177	3.56e-259	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
NEHPIGDC_03179	1.45e-78	-	-	-	S	-	-	-	TraX protein
NEHPIGDC_03182	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NEHPIGDC_03183	6.92e-106	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
NEHPIGDC_03184	7.04e-153	-	-	-	EGP	-	-	-	Necrosis inducing protein (NPP1)
NEHPIGDC_03185	2.23e-132	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NEHPIGDC_03186	1.76e-33	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
NEHPIGDC_03187	1.42e-102	yqaS	-	-	L	-	-	-	DNA packaging
NEHPIGDC_03188	0.000188	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NEHPIGDC_03189	1.71e-137	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
NEHPIGDC_03192	1.62e-30	ydaT	-	-	-	-	-	-	-
NEHPIGDC_03195	2.51e-93	yqaQ	-	-	L	-	-	-	Transposase
NEHPIGDC_03197	9.1e-27	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
NEHPIGDC_03198	2.49e-43	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
NEHPIGDC_03200	3.57e-49	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
NEHPIGDC_03202	1.52e-203	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NEHPIGDC_03203	1.07e-116	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NEHPIGDC_03204	2.22e-125	yqaC	-	-	F	-	-	-	adenylate kinase activity
NEHPIGDC_03205	1.81e-78	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NEHPIGDC_03206	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
NEHPIGDC_03207	1.21e-304	yrkQ	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_03208	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
NEHPIGDC_03209	1.34e-280	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NEHPIGDC_03210	5.41e-134	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NEHPIGDC_03211	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
NEHPIGDC_03212	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
NEHPIGDC_03213	5.31e-155	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEHPIGDC_03214	1.3e-48	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
NEHPIGDC_03215	6.93e-262	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
NEHPIGDC_03216	1.61e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
NEHPIGDC_03217	1.61e-107	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
NEHPIGDC_03218	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03219	2.21e-138	yrkC	-	-	G	-	-	-	Cupin domain
NEHPIGDC_03220	3.56e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NEHPIGDC_03221	1.31e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_03222	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
NEHPIGDC_03223	3.73e-300	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NEHPIGDC_03224	7.28e-218	yrdR	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_03225	2.83e-203	-	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_03226	2.89e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
NEHPIGDC_03227	1.61e-201	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
NEHPIGDC_03228	1.75e-87	yodA	-	-	S	-	-	-	tautomerase
NEHPIGDC_03229	2.43e-208	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
NEHPIGDC_03230	5.81e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NEHPIGDC_03231	5.64e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NEHPIGDC_03232	2.29e-176	azlC	-	-	E	-	-	-	AzlC protein
NEHPIGDC_03233	8.34e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
NEHPIGDC_03234	2.73e-33	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
NEHPIGDC_03235	1.44e-294	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NEHPIGDC_03237	2.11e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
NEHPIGDC_03238	2.99e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
NEHPIGDC_03239	2.75e-116	yrdA	-	-	S	-	-	-	DinB family
NEHPIGDC_03240	2.98e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
NEHPIGDC_03241	3.48e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NEHPIGDC_03242	3.66e-183	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NEHPIGDC_03243	5.63e-161	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
NEHPIGDC_03245	2.98e-166	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NEHPIGDC_03246	6.39e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_03247	2.83e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
NEHPIGDC_03248	1.25e-284	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
NEHPIGDC_03249	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_03250	9.87e-262	yraM	-	-	S	-	-	-	PrpF protein
NEHPIGDC_03252	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NEHPIGDC_03253	5.07e-56	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEHPIGDC_03254	8.04e-190	-	-	-	S	-	-	-	Alpha beta hydrolase
NEHPIGDC_03255	1.33e-79	-	-	-	T	-	-	-	sh3 domain protein
NEHPIGDC_03256	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
NEHPIGDC_03257	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
NEHPIGDC_03258	1.2e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
NEHPIGDC_03259	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
NEHPIGDC_03260	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NEHPIGDC_03261	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
NEHPIGDC_03262	1.46e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
NEHPIGDC_03263	3.17e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
NEHPIGDC_03264	1.38e-252	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
NEHPIGDC_03265	9.17e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
NEHPIGDC_03266	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
NEHPIGDC_03267	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NEHPIGDC_03268	2.79e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NEHPIGDC_03269	8.91e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
NEHPIGDC_03270	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
NEHPIGDC_03271	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
NEHPIGDC_03272	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_03273	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
NEHPIGDC_03274	1.62e-191	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
NEHPIGDC_03275	8.2e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_03276	7.4e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
NEHPIGDC_03277	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
NEHPIGDC_03278	2.67e-62	yrhK	-	-	S	-	-	-	YrhK-like protein
NEHPIGDC_03279	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
NEHPIGDC_03280	4.57e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
NEHPIGDC_03281	7.42e-125	yrhH	-	-	Q	-	-	-	methyltransferase
NEHPIGDC_03282	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
NEHPIGDC_03284	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
NEHPIGDC_03285	1.08e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
NEHPIGDC_03286	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
NEHPIGDC_03287	1.22e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NEHPIGDC_03288	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
NEHPIGDC_03289	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NEHPIGDC_03290	4.75e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
NEHPIGDC_03291	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEHPIGDC_03292	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
NEHPIGDC_03293	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
NEHPIGDC_03294	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
NEHPIGDC_03295	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
NEHPIGDC_03296	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEHPIGDC_03297	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NEHPIGDC_03298	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
NEHPIGDC_03299	6.57e-224	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
NEHPIGDC_03300	1.7e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
NEHPIGDC_03301	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEHPIGDC_03302	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NEHPIGDC_03303	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEHPIGDC_03304	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NEHPIGDC_03305	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEHPIGDC_03306	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
NEHPIGDC_03307	9.37e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NEHPIGDC_03308	1.28e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
NEHPIGDC_03309	2.28e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEHPIGDC_03310	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEHPIGDC_03311	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
NEHPIGDC_03312	8.4e-42	yrzR	-	-	-	-	-	-	-
NEHPIGDC_03313	3.54e-108	yrrD	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03314	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEHPIGDC_03315	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
NEHPIGDC_03316	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEHPIGDC_03317	2.67e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NEHPIGDC_03318	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_03319	8.5e-304	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NEHPIGDC_03320	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NEHPIGDC_03321	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEHPIGDC_03322	8.6e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NEHPIGDC_03324	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
NEHPIGDC_03325	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEHPIGDC_03326	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEHPIGDC_03327	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEHPIGDC_03328	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NEHPIGDC_03329	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NEHPIGDC_03330	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
NEHPIGDC_03331	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NEHPIGDC_03332	6.47e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
NEHPIGDC_03333	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_03334	4.1e-143	yrbG	-	-	S	-	-	-	membrane
NEHPIGDC_03335	1.46e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
NEHPIGDC_03336	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
NEHPIGDC_03337	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEHPIGDC_03338	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEHPIGDC_03339	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
NEHPIGDC_03340	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEHPIGDC_03341	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEHPIGDC_03342	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
NEHPIGDC_03343	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
NEHPIGDC_03344	7.93e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NEHPIGDC_03345	2.32e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
NEHPIGDC_03347	6.26e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
NEHPIGDC_03348	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NEHPIGDC_03349	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
NEHPIGDC_03350	2.55e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NEHPIGDC_03351	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
NEHPIGDC_03352	2.66e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NEHPIGDC_03353	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
NEHPIGDC_03354	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NEHPIGDC_03355	6.77e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NEHPIGDC_03356	8.33e-122	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
NEHPIGDC_03357	4.99e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NEHPIGDC_03358	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
NEHPIGDC_03359	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEHPIGDC_03360	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
NEHPIGDC_03361	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NEHPIGDC_03362	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
NEHPIGDC_03363	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NEHPIGDC_03364	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
NEHPIGDC_03365	1.83e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NEHPIGDC_03366	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NEHPIGDC_03367	2.05e-156	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NEHPIGDC_03368	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
NEHPIGDC_03369	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NEHPIGDC_03370	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
NEHPIGDC_03371	2.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NEHPIGDC_03372	4.97e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
NEHPIGDC_03373	2.75e-207	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
NEHPIGDC_03374	3.08e-162	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NEHPIGDC_03375	2.22e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NEHPIGDC_03376	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEHPIGDC_03377	1.53e-35	-	-	-	-	-	-	-	-
NEHPIGDC_03378	4.82e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NEHPIGDC_03379	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
NEHPIGDC_03380	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NEHPIGDC_03381	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
NEHPIGDC_03382	2.91e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NEHPIGDC_03383	3.63e-219	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NEHPIGDC_03384	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
NEHPIGDC_03385	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NEHPIGDC_03386	8.23e-117	ysxD	-	-	-	-	-	-	-
NEHPIGDC_03387	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NEHPIGDC_03388	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NEHPIGDC_03389	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
NEHPIGDC_03390	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEHPIGDC_03391	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEHPIGDC_03392	1.11e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
NEHPIGDC_03393	7.31e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEHPIGDC_03394	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEHPIGDC_03395	7.43e-256	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEHPIGDC_03396	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEHPIGDC_03397	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEHPIGDC_03398	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NEHPIGDC_03399	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NEHPIGDC_03401	5.41e-45	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
NEHPIGDC_03402	5.32e-186	-	-	-	N	-	-	-	domain, Protein
NEHPIGDC_03403	8.27e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03404	1.72e-125	-	-	-	K	-	-	-	Helix-turn-helix domain
NEHPIGDC_03405	7.56e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEHPIGDC_03406	4.2e-82	-	-	-	-	-	-	-	-
NEHPIGDC_03407	8.49e-159	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
NEHPIGDC_03409	8.37e-29	-	-	-	S	-	-	-	protein disulfide oxidoreductase activity
NEHPIGDC_03412	3e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
NEHPIGDC_03413	2.39e-189	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NEHPIGDC_03414	3.73e-40	-	-	-	S	-	-	-	Haemolysin XhlA
NEHPIGDC_03415	3.73e-06	-	-	-	-	-	-	-	-
NEHPIGDC_03417	1.5e-49	-	-	-	-	-	-	-	-
NEHPIGDC_03418	3.33e-85	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
NEHPIGDC_03420	6.05e-143	-	-	-	D	-	-	-	Phage tail tape measure protein
NEHPIGDC_03421	8.01e-44	-	-	-	-	-	-	-	-
NEHPIGDC_03422	1.11e-93	-	-	-	N	-	-	-	phage major tail protein, phi13 family
NEHPIGDC_03423	4.25e-33	-	-	-	-	-	-	-	-
NEHPIGDC_03425	8.33e-44	-	-	-	S	-	-	-	Phage head-tail joining protein
NEHPIGDC_03426	4.64e-35	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NEHPIGDC_03427	6.17e-56	-	-	-	N	-	-	-	domain, Protein
NEHPIGDC_03428	2.48e-220	-	-	-	S	-	-	-	Phage capsid family
NEHPIGDC_03429	3.3e-157	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NEHPIGDC_03430	6.96e-284	-	-	-	S	-	-	-	Phage portal protein
NEHPIGDC_03431	0.0	-	-	-	S	-	-	-	Terminase
NEHPIGDC_03432	1.92e-58	-	-	-	L	-	-	-	Phage terminase, small subunit
NEHPIGDC_03433	3.2e-41	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
NEHPIGDC_03435	7e-70	-	-	-	-	-	-	-	-
NEHPIGDC_03441	3.16e-49	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NEHPIGDC_03442	3.58e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEHPIGDC_03443	1.1e-70	-	-	-	S	-	-	-	Pfam:DUF867
NEHPIGDC_03444	7.03e-145	-	-	-	M	-	-	-	Right handed beta helix region
NEHPIGDC_03447	5.9e-64	-	-	-	-	-	-	-	-
NEHPIGDC_03449	1.48e-32	-	-	-	-	-	-	-	-
NEHPIGDC_03451	6.21e-12	-	-	-	-	-	-	-	-
NEHPIGDC_03452	5.08e-72	-	-	-	-	-	-	-	-
NEHPIGDC_03453	2.65e-57	-	-	-	K	-	-	-	Sigma-70, region 4
NEHPIGDC_03455	2.16e-168	-	-	-	S	-	-	-	C-5 cytosine-specific DNA methylase
NEHPIGDC_03456	1.44e-27	-	-	-	-	-	-	-	-
NEHPIGDC_03457	7.7e-55	-	-	-	-	-	-	-	-
NEHPIGDC_03458	4.11e-53	-	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03459	9.13e-143	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEHPIGDC_03461	1.72e-73	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
NEHPIGDC_03462	3.03e-194	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPIGDC_03464	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEHPIGDC_03465	1.61e-62	-	-	-	S	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
NEHPIGDC_03466	2.32e-50	-	-	-	F	-	-	-	Belongs to the NrdI family
NEHPIGDC_03473	7.56e-212	-	-	-	-	-	-	-	-
NEHPIGDC_03475	2.51e-130	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
NEHPIGDC_03476	1.13e-241	-	-	-	L	-	-	-	DNA polymerase A domain
NEHPIGDC_03479	1.3e-63	-	-	-	-	-	-	-	-
NEHPIGDC_03480	3.17e-61	-	-	-	-	-	-	-	-
NEHPIGDC_03486	1.05e-12	-	-	-	S	-	-	-	Cro/C1-type HTH DNA-binding domain
NEHPIGDC_03487	2.1e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEHPIGDC_03488	2.32e-176	-	-	-	L	-	-	-	Toprim-like
NEHPIGDC_03489	3.45e-178	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
NEHPIGDC_03492	4.2e-113	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
NEHPIGDC_03494	4.36e-112	-	-	-	-	-	-	-	-
NEHPIGDC_03496	5.88e-22	-	-	-	-	-	-	-	-
NEHPIGDC_03501	2.55e-110	-	-	-	L	-	-	-	Phage integrase family
NEHPIGDC_03503	2.34e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NEHPIGDC_03504	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEHPIGDC_03505	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEHPIGDC_03506	1.14e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
NEHPIGDC_03507	1.83e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NEHPIGDC_03508	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_03509	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_03510	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
NEHPIGDC_03511	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NEHPIGDC_03512	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NEHPIGDC_03513	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
NEHPIGDC_03514	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NEHPIGDC_03515	4.83e-276	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NEHPIGDC_03516	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEHPIGDC_03517	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NEHPIGDC_03518	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
NEHPIGDC_03520	1.23e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
NEHPIGDC_03521	7.4e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
NEHPIGDC_03522	3.12e-176	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
NEHPIGDC_03523	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_03524	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NEHPIGDC_03525	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
NEHPIGDC_03526	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEHPIGDC_03527	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
NEHPIGDC_03528	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
NEHPIGDC_03529	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEHPIGDC_03530	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEHPIGDC_03531	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHPIGDC_03532	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEHPIGDC_03533	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHPIGDC_03534	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
NEHPIGDC_03535	3.06e-261	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
NEHPIGDC_03536	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NEHPIGDC_03537	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
NEHPIGDC_03538	1.26e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
NEHPIGDC_03539	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
NEHPIGDC_03540	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
NEHPIGDC_03541	1.23e-189	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
NEHPIGDC_03542	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
NEHPIGDC_03543	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
NEHPIGDC_03544	4.34e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NEHPIGDC_03545	6.06e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
NEHPIGDC_03546	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NEHPIGDC_03547	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
NEHPIGDC_03548	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NEHPIGDC_03549	8.15e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
NEHPIGDC_03550	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
NEHPIGDC_03551	2.29e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
NEHPIGDC_03552	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
NEHPIGDC_03553	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEHPIGDC_03554	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NEHPIGDC_03555	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEHPIGDC_03557	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NEHPIGDC_03558	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NEHPIGDC_03559	1.13e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
NEHPIGDC_03560	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_03561	2.07e-191	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NEHPIGDC_03562	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEHPIGDC_03563	1.41e-204	ytxC	-	-	S	-	-	-	YtxC-like family
NEHPIGDC_03564	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_03565	2.11e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NEHPIGDC_03566	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
NEHPIGDC_03567	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEHPIGDC_03568	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NEHPIGDC_03569	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEHPIGDC_03570	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_03571	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
NEHPIGDC_03572	4.54e-205	ytbE	-	-	S	-	-	-	reductase
NEHPIGDC_03573	7.74e-124	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEHPIGDC_03574	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NEHPIGDC_03575	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEHPIGDC_03576	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEHPIGDC_03577	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
NEHPIGDC_03578	3.27e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_03579	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
NEHPIGDC_03580	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
NEHPIGDC_03581	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NEHPIGDC_03582	1.56e-93	ytwI	-	-	S	-	-	-	membrane
NEHPIGDC_03583	1.11e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
NEHPIGDC_03584	4.68e-82	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
NEHPIGDC_03585	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NEHPIGDC_03586	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEHPIGDC_03587	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NEHPIGDC_03588	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEHPIGDC_03589	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NEHPIGDC_03590	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NEHPIGDC_03591	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
NEHPIGDC_03592	5.12e-112	ytrI	-	-	-	-	-	-	-
NEHPIGDC_03593	1.15e-39	-	-	-	-	-	-	-	-
NEHPIGDC_03594	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
NEHPIGDC_03595	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
NEHPIGDC_03596	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
NEHPIGDC_03597	1.24e-203	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEHPIGDC_03598	9.52e-303	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
NEHPIGDC_03599	6.9e-166	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
NEHPIGDC_03600	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_03601	5.26e-63	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
NEHPIGDC_03602	1.52e-237	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_03603	6.61e-183	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NEHPIGDC_03604	4.76e-155	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_03605	1.66e-157	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NEHPIGDC_03606	4.01e-194	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NEHPIGDC_03607	5.27e-194	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NEHPIGDC_03608	8.39e-130	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NEHPIGDC_03609	4.99e-223	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
NEHPIGDC_03610	4.53e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
NEHPIGDC_03611	1.98e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NEHPIGDC_03613	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NEHPIGDC_03614	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEHPIGDC_03615	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NEHPIGDC_03616	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEHPIGDC_03617	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NEHPIGDC_03618	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEHPIGDC_03619	2.24e-96	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
NEHPIGDC_03620	5.63e-147	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
NEHPIGDC_03621	4.08e-112	yteJ	-	-	S	-	-	-	RDD family
NEHPIGDC_03622	2.79e-229	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
NEHPIGDC_03623	4.85e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEHPIGDC_03624	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
NEHPIGDC_03625	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NEHPIGDC_03626	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
NEHPIGDC_03627	8.52e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEHPIGDC_03628	3.2e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NEHPIGDC_03629	4.75e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NEHPIGDC_03630	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEHPIGDC_03631	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NEHPIGDC_03632	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_03633	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NEHPIGDC_03634	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
NEHPIGDC_03635	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEHPIGDC_03637	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEHPIGDC_03638	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NEHPIGDC_03639	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NEHPIGDC_03640	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
NEHPIGDC_03641	2.65e-292	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
NEHPIGDC_03642	1.15e-157	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
NEHPIGDC_03643	3.96e-186	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
NEHPIGDC_03644	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NEHPIGDC_03645	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NEHPIGDC_03646	1.57e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
NEHPIGDC_03647	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
NEHPIGDC_03648	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEHPIGDC_03649	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NEHPIGDC_03650	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NEHPIGDC_03651	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEHPIGDC_03652	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
NEHPIGDC_03653	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
NEHPIGDC_03654	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
NEHPIGDC_03655	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
NEHPIGDC_03656	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
NEHPIGDC_03657	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NEHPIGDC_03658	1.2e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NEHPIGDC_03659	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEHPIGDC_03660	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
NEHPIGDC_03661	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
NEHPIGDC_03662	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
NEHPIGDC_03663	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NEHPIGDC_03664	4.92e-212	ytlQ	-	-	-	-	-	-	-
NEHPIGDC_03665	1.75e-129	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NEHPIGDC_03666	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NEHPIGDC_03667	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
NEHPIGDC_03668	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NEHPIGDC_03669	1.28e-257	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
NEHPIGDC_03670	3.27e-167	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NEHPIGDC_03671	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
NEHPIGDC_03672	1.23e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NEHPIGDC_03673	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_03674	1.41e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
NEHPIGDC_03675	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NEHPIGDC_03676	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
NEHPIGDC_03677	2.3e-151	yteU	-	-	S	-	-	-	Integral membrane protein
NEHPIGDC_03678	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NEHPIGDC_03679	2.76e-93	yteS	-	-	G	-	-	-	transport
NEHPIGDC_03680	1.96e-277	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NEHPIGDC_03681	2.27e-221	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NEHPIGDC_03682	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
NEHPIGDC_03683	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
NEHPIGDC_03684	1.25e-185	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NEHPIGDC_03685	4.28e-176	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
NEHPIGDC_03686	1.03e-284	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
NEHPIGDC_03687	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NEHPIGDC_03688	1.62e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NEHPIGDC_03689	1.05e-274	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NEHPIGDC_03690	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NEHPIGDC_03691	5.51e-180	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NEHPIGDC_03692	7.95e-220	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
NEHPIGDC_03693	8.83e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NEHPIGDC_03694	3.51e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NEHPIGDC_03695	9.58e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEHPIGDC_03696	2.19e-185	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NEHPIGDC_03697	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NEHPIGDC_03698	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
NEHPIGDC_03699	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NEHPIGDC_03700	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
NEHPIGDC_03701	1.56e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NEHPIGDC_03702	9.96e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
NEHPIGDC_03703	6.61e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
NEHPIGDC_03704	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
NEHPIGDC_03705	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_03706	1.58e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
NEHPIGDC_03707	1.77e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_03708	1.14e-295	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NEHPIGDC_03709	8.35e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_03710	3.36e-193	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
NEHPIGDC_03711	2.4e-199	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NEHPIGDC_03712	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_03713	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
NEHPIGDC_03715	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
NEHPIGDC_03716	9.56e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
NEHPIGDC_03717	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
NEHPIGDC_03718	3.25e-274	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
NEHPIGDC_03719	4.7e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
NEHPIGDC_03720	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NEHPIGDC_03721	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_03722	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NEHPIGDC_03723	2.64e-285	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEHPIGDC_03724	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NEHPIGDC_03725	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
NEHPIGDC_03726	4.51e-189	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NEHPIGDC_03727	5.36e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NEHPIGDC_03728	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NEHPIGDC_03729	1.09e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NEHPIGDC_03730	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NEHPIGDC_03731	6.47e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
NEHPIGDC_03732	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NEHPIGDC_03734	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
NEHPIGDC_03735	6.88e-112	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEHPIGDC_03736	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NEHPIGDC_03737	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NEHPIGDC_03738	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
NEHPIGDC_03739	1.34e-237	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NEHPIGDC_03740	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
NEHPIGDC_03741	7.92e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NEHPIGDC_03742	7.45e-296	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NEHPIGDC_03743	6.86e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NEHPIGDC_03744	2.65e-217	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NEHPIGDC_03745	7.07e-273	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NEHPIGDC_03746	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NEHPIGDC_03747	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NEHPIGDC_03748	1.15e-195	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NEHPIGDC_03749	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NEHPIGDC_03750	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
NEHPIGDC_03751	3.53e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
NEHPIGDC_03752	1.4e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NEHPIGDC_03753	2.03e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEHPIGDC_03754	3.15e-230	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
NEHPIGDC_03755	4.32e-299	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
NEHPIGDC_03757	6.94e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
NEHPIGDC_03758	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
NEHPIGDC_03759	1.83e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
NEHPIGDC_03760	4.54e-54	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
NEHPIGDC_03761	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEHPIGDC_03762	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
NEHPIGDC_03763	6.43e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
NEHPIGDC_03764	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEHPIGDC_03765	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEHPIGDC_03787	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
NEHPIGDC_03788	1.56e-131	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NEHPIGDC_03789	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
NEHPIGDC_03790	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
NEHPIGDC_03791	1.63e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEHPIGDC_03792	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03793	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
NEHPIGDC_03794	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NEHPIGDC_03795	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
NEHPIGDC_03796	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NEHPIGDC_03797	1.34e-176	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
NEHPIGDC_03798	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
NEHPIGDC_03799	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEHPIGDC_03800	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
NEHPIGDC_03801	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEHPIGDC_03802	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
NEHPIGDC_03803	1.67e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
NEHPIGDC_03804	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEHPIGDC_03805	2.91e-198	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEHPIGDC_03806	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
NEHPIGDC_03807	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03808	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEHPIGDC_03809	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NEHPIGDC_03810	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
NEHPIGDC_03811	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NEHPIGDC_03812	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEHPIGDC_03813	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEHPIGDC_03814	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEHPIGDC_03815	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEHPIGDC_03816	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
NEHPIGDC_03817	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEHPIGDC_03818	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
NEHPIGDC_03819	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEHPIGDC_03820	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NEHPIGDC_03821	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NEHPIGDC_03822	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
NEHPIGDC_03823	7.4e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
NEHPIGDC_03824	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NEHPIGDC_03825	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NEHPIGDC_03828	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
NEHPIGDC_03829	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NEHPIGDC_03830	8.42e-237	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NEHPIGDC_03831	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEHPIGDC_03832	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
NEHPIGDC_03833	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEHPIGDC_03834	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEHPIGDC_03835	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEHPIGDC_03836	1.11e-194	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
NEHPIGDC_03837	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NEHPIGDC_03838	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEHPIGDC_03839	1.72e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
NEHPIGDC_03840	4.4e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
NEHPIGDC_03841	4.72e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEHPIGDC_03842	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEHPIGDC_03843	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NEHPIGDC_03844	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
NEHPIGDC_03845	3.21e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEHPIGDC_03846	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NEHPIGDC_03847	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
NEHPIGDC_03849	3.77e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
NEHPIGDC_03850	6.65e-183	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
NEHPIGDC_03851	5.82e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_03852	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEHPIGDC_03853	1.99e-213	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
NEHPIGDC_03854	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
NEHPIGDC_03855	1.41e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03856	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
NEHPIGDC_03857	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
NEHPIGDC_03858	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_03859	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
NEHPIGDC_03860	2.24e-208	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEHPIGDC_03861	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
NEHPIGDC_03862	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
NEHPIGDC_03868	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_03869	1.3e-150	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NEHPIGDC_03870	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEHPIGDC_03871	1.44e-290	ybbR	-	-	S	-	-	-	protein conserved in bacteria
NEHPIGDC_03872	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEHPIGDC_03873	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEHPIGDC_03874	7.97e-222	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NEHPIGDC_03875	8.8e-155	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
NEHPIGDC_03876	2.14e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEHPIGDC_03877	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NEHPIGDC_03878	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
NEHPIGDC_03879	1.63e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
NEHPIGDC_03880	5.59e-64	-	-	-	-	-	-	-	-
NEHPIGDC_03881	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
NEHPIGDC_03882	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
NEHPIGDC_03883	1.27e-255	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NEHPIGDC_03884	1.66e-73	-	-	-	-	-	-	-	-
NEHPIGDC_03885	1.56e-230	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NEHPIGDC_03886	2.93e-159	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
NEHPIGDC_03887	1.38e-219	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
NEHPIGDC_03889	5.87e-180	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
NEHPIGDC_03890	4.28e-192	ybdN	-	-	-	-	-	-	-
NEHPIGDC_03891	1.81e-273	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
NEHPIGDC_03892	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_03893	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
NEHPIGDC_03894	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
NEHPIGDC_03895	8.11e-86	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
NEHPIGDC_03896	8.81e-86	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
NEHPIGDC_03897	9.37e-315	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
NEHPIGDC_03898	1.11e-54	ybyB	-	-	-	-	-	-	-
NEHPIGDC_03899	0.0	ybeC	-	-	E	-	-	-	amino acid
NEHPIGDC_03900	7.3e-213	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
NEHPIGDC_03901	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
NEHPIGDC_03902	1.02e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
NEHPIGDC_03903	2.02e-216	ybfA	-	-	K	-	-	-	FR47-like protein
NEHPIGDC_03904	6.47e-285	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_03906	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
NEHPIGDC_03907	5.89e-205	ybfH	-	-	EG	-	-	-	EamA-like transporter family
NEHPIGDC_03908	6.79e-184	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
NEHPIGDC_03909	3.24e-271	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEHPIGDC_03910	4.14e-229	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
NEHPIGDC_03912	7.27e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NEHPIGDC_03913	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEHPIGDC_03914	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
NEHPIGDC_03915	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NEHPIGDC_03916	3.88e-60	ybfN	-	-	-	-	-	-	-
NEHPIGDC_03917	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
NEHPIGDC_03918	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEHPIGDC_03919	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NEHPIGDC_03920	1.43e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEHPIGDC_03921	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
NEHPIGDC_03923	2.3e-257	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NEHPIGDC_03924	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NEHPIGDC_03925	3.55e-231	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
NEHPIGDC_03927	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
NEHPIGDC_03928	1.46e-236	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NEHPIGDC_03929	2.05e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEHPIGDC_03930	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
NEHPIGDC_03931	1.67e-221	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
NEHPIGDC_03932	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NEHPIGDC_03933	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NEHPIGDC_03934	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NEHPIGDC_03935	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
NEHPIGDC_03936	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NEHPIGDC_03937	6.07e-223	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
NEHPIGDC_03938	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
NEHPIGDC_03939	2.1e-217	eamA1	-	-	EG	-	-	-	spore germination
NEHPIGDC_03940	3.71e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEHPIGDC_03941	2.26e-216	ycbM	-	-	T	-	-	-	Histidine kinase
NEHPIGDC_03942	6.47e-214	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEHPIGDC_03943	1.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
NEHPIGDC_03944	2.21e-76	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NEHPIGDC_03945	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
NEHPIGDC_03946	3.83e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
NEHPIGDC_03947	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
NEHPIGDC_03948	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEHPIGDC_03949	3.61e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEHPIGDC_03950	9.85e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEHPIGDC_03951	5.08e-261	ycbU	-	-	E	-	-	-	Selenocysteine lyase
NEHPIGDC_03952	6.85e-300	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NEHPIGDC_03953	4.42e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
NEHPIGDC_03954	3.41e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NEHPIGDC_03955	1.63e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NEHPIGDC_03956	2.31e-73	-	-	-	S	-	-	-	RDD family
NEHPIGDC_03957	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
NEHPIGDC_03958	6.18e-213	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NEHPIGDC_03959	1.33e-160	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NEHPIGDC_03960	4.45e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NEHPIGDC_03961	7.66e-255	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NEHPIGDC_03962	1.95e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
NEHPIGDC_03963	7.81e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
NEHPIGDC_03964	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_03965	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NEHPIGDC_03966	4.57e-124	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NEHPIGDC_03967	2.86e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
NEHPIGDC_03968	3.39e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
NEHPIGDC_03969	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
NEHPIGDC_03970	7.92e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NEHPIGDC_03971	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NEHPIGDC_03972	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NEHPIGDC_03973	7.24e-239	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NEHPIGDC_03974	2.17e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
NEHPIGDC_03975	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NEHPIGDC_03976	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
NEHPIGDC_03977	1.37e-174	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
NEHPIGDC_03978	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
NEHPIGDC_03979	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
NEHPIGDC_03980	2.7e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
NEHPIGDC_03981	1.17e-267	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
NEHPIGDC_03982	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NEHPIGDC_03983	3.66e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
NEHPIGDC_03984	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NEHPIGDC_03985	1.16e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NEHPIGDC_03986	1.97e-276	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
NEHPIGDC_03987	0.0	ycgA	-	-	S	-	-	-	Membrane
NEHPIGDC_03988	4.5e-104	ycgB	-	-	-	-	-	-	-
NEHPIGDC_03989	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
NEHPIGDC_03990	5.91e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEHPIGDC_03991	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NEHPIGDC_03992	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
NEHPIGDC_03993	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NEHPIGDC_03994	2.61e-146	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
NEHPIGDC_03995	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
NEHPIGDC_03996	9.32e-317	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NEHPIGDC_03997	4.4e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
NEHPIGDC_03998	7.44e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEHPIGDC_03999	3.61e-138	tmrB	-	-	S	-	-	-	AAA domain
NEHPIGDC_04001	3.01e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEHPIGDC_04002	4.15e-183	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NEHPIGDC_04003	2.99e-223	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
NEHPIGDC_04004	7.75e-232	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
NEHPIGDC_04005	7.76e-187	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
NEHPIGDC_04006	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NEHPIGDC_04007	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
NEHPIGDC_04008	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEHPIGDC_04009	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
NEHPIGDC_04010	3.03e-193	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
NEHPIGDC_04011	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
NEHPIGDC_04012	3.19e-201	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
NEHPIGDC_04013	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NEHPIGDC_04014	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NEHPIGDC_04015	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
NEHPIGDC_04016	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NEHPIGDC_04017	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEHPIGDC_04018	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
NEHPIGDC_04019	6.43e-282	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NEHPIGDC_04020	1.05e-222	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
NEHPIGDC_04021	1.04e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
NEHPIGDC_04022	1.6e-289	yciC	-	-	S	-	-	-	GTPases (G3E family)
NEHPIGDC_04023	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NEHPIGDC_04024	3.76e-187	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NEHPIGDC_04025	1.69e-56	yckC	-	-	S	-	-	-	membrane
NEHPIGDC_04026	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
NEHPIGDC_04027	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NEHPIGDC_04028	2.77e-90	nin	-	-	S	-	-	-	Competence protein J (ComJ)
NEHPIGDC_04029	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
NEHPIGDC_04030	7.55e-268	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NEHPIGDC_04031	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
NEHPIGDC_04032	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
NEHPIGDC_04033	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
NEHPIGDC_04034	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NEHPIGDC_04035	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
NEHPIGDC_04036	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NEHPIGDC_04037	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NEHPIGDC_04038	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEHPIGDC_04039	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NEHPIGDC_04040	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
NEHPIGDC_04041	1.82e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEHPIGDC_04042	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEHPIGDC_04043	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEHPIGDC_04044	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
NEHPIGDC_04045	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEHPIGDC_04046	2.04e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEHPIGDC_04047	4.29e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEHPIGDC_04048	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
NEHPIGDC_04049	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
NEHPIGDC_04050	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEHPIGDC_04051	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NEHPIGDC_04052	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEHPIGDC_04053	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEHPIGDC_04054	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEHPIGDC_04055	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEHPIGDC_04056	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NEHPIGDC_04057	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPIGDC_04058	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPIGDC_04059	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
NEHPIGDC_04060	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEHPIGDC_04061	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEHPIGDC_04062	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEHPIGDC_04063	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEHPIGDC_04064	5.46e-232	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
NEHPIGDC_04065	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NEHPIGDC_04066	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEHPIGDC_04067	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NEHPIGDC_04068	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEHPIGDC_04069	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEHPIGDC_04070	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEHPIGDC_04071	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEHPIGDC_04072	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEHPIGDC_04073	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEHPIGDC_04074	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NEHPIGDC_04075	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEHPIGDC_04076	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEHPIGDC_04077	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEHPIGDC_04078	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEHPIGDC_04079	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEHPIGDC_04080	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEHPIGDC_04081	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEHPIGDC_04082	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEHPIGDC_04083	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEHPIGDC_04084	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NEHPIGDC_04085	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NEHPIGDC_04086	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEHPIGDC_04087	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEHPIGDC_04088	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NEHPIGDC_04089	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEHPIGDC_04090	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NEHPIGDC_04091	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEHPIGDC_04092	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEHPIGDC_04093	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEHPIGDC_04094	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NEHPIGDC_04095	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPIGDC_04096	1.83e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPIGDC_04097	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEHPIGDC_04098	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEHPIGDC_04099	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEHPIGDC_04100	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NEHPIGDC_04101	6.15e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
NEHPIGDC_04102	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
NEHPIGDC_04103	9.05e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NEHPIGDC_04104	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEHPIGDC_04105	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
NEHPIGDC_04106	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
NEHPIGDC_04107	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
NEHPIGDC_04108	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
NEHPIGDC_04110	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_04111	4.23e-231	yaaC	-	-	S	-	-	-	YaaC-like Protein
NEHPIGDC_04112	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEHPIGDC_04113	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NEHPIGDC_04114	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NEHPIGDC_04115	3.9e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NEHPIGDC_04116	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEHPIGDC_04118	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
NEHPIGDC_04119	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
NEHPIGDC_04120	5.18e-276	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
NEHPIGDC_04121	1.62e-124	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
NEHPIGDC_04122	4.98e-107	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEHPIGDC_04123	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEHPIGDC_04124	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEHPIGDC_04125	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEHPIGDC_04126	3.13e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NEHPIGDC_04127	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
NEHPIGDC_04130	3.34e-39	-	-	-	L	-	-	-	Phage integrase family
NEHPIGDC_04131	2.75e-35	-	-	-	L	-	-	-	Phage integrase family
NEHPIGDC_04133	3.09e-28	-	-	-	-	-	-	-	-
NEHPIGDC_04134	2.82e-65	bldD	-	-	K	ko:K07110,ko:K21572	-	ko00000,ko02000,ko03000	domain, Protein
NEHPIGDC_04135	6.82e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEHPIGDC_04137	1.62e-15	-	-	-	-	-	-	-	-
NEHPIGDC_04138	4.38e-23	-	-	-	-	-	-	-	-
NEHPIGDC_04139	2.07e-16	bet	-	-	L	-	-	-	RecT family
NEHPIGDC_04140	3.29e-41	-	-	-	-	-	-	-	-
NEHPIGDC_04143	1.56e-45	-	-	-	-	-	-	-	-
NEHPIGDC_04147	1.6e-71	-	-	-	K	-	-	-	DNA binding
NEHPIGDC_04148	3.86e-156	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NEHPIGDC_04149	3.75e-21	-	-	-	-	-	-	-	-
NEHPIGDC_04151	1.92e-40	-	-	-	-	-	-	-	-
NEHPIGDC_04153	1.86e-23	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
NEHPIGDC_04155	3.42e-55	-	-	-	-	-	-	-	-
NEHPIGDC_04156	2.64e-257	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
NEHPIGDC_04158	2.4e-76	-	-	-	-	-	-	-	-
NEHPIGDC_04163	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEHPIGDC_04164	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall