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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLDNKGNC_00001	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_00002	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HLDNKGNC_00003	2.48e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HLDNKGNC_00004	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HLDNKGNC_00005	2.71e-54	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
HLDNKGNC_00006	3.76e-268	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HLDNKGNC_00007	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLDNKGNC_00008	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HLDNKGNC_00009	1.19e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HLDNKGNC_00010	9.56e-212	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HLDNKGNC_00011	2.87e-173	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HLDNKGNC_00012	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLDNKGNC_00013	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HLDNKGNC_00014	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
HLDNKGNC_00015	1.58e-209	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLDNKGNC_00016	1.72e-103	yngA	-	-	S	-	-	-	membrane
HLDNKGNC_00017	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLDNKGNC_00018	7.88e-316	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HLDNKGNC_00020	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HLDNKGNC_00021	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HLDNKGNC_00022	1.06e-75	ynfC	-	-	-	-	-	-	-
HLDNKGNC_00023	1.82e-18	-	-	-	-	-	-	-	-
HLDNKGNC_00024	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDNKGNC_00025	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLDNKGNC_00026	1.21e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HLDNKGNC_00027	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLDNKGNC_00028	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HLDNKGNC_00029	6.65e-71	yneQ	-	-	-	-	-	-	-
HLDNKGNC_00030	1.64e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HLDNKGNC_00031	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HLDNKGNC_00033	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
HLDNKGNC_00034	1.25e-118	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLDNKGNC_00035	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLDNKGNC_00036	3.27e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HLDNKGNC_00037	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HLDNKGNC_00038	2.35e-84	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HLDNKGNC_00039	8.01e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HLDNKGNC_00040	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HLDNKGNC_00041	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HLDNKGNC_00042	1.18e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HLDNKGNC_00043	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HLDNKGNC_00044	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HLDNKGNC_00045	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HLDNKGNC_00046	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLDNKGNC_00047	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HLDNKGNC_00048	1.88e-143	yneB	-	-	L	-	-	-	resolvase
HLDNKGNC_00049	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HLDNKGNC_00050	1.46e-141	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLDNKGNC_00051	2.54e-95	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HLDNKGNC_00052	1.32e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HLDNKGNC_00053	1.33e-174	yndL	-	-	S	-	-	-	Replication protein
HLDNKGNC_00055	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HLDNKGNC_00056	1.47e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HLDNKGNC_00057	5.93e-195	yndG	-	-	S	-	-	-	DoxX-like family
HLDNKGNC_00058	5.57e-289	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HLDNKGNC_00059	4.59e-249	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
HLDNKGNC_00060	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLDNKGNC_00063	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HLDNKGNC_00064	2.99e-94	-	-	-	-	-	-	-	-
HLDNKGNC_00065	1.96e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
HLDNKGNC_00068	3.99e-163	-	-	-	S	-	-	-	Domain of unknown function, YrpD
HLDNKGNC_00070	4.75e-211	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLDNKGNC_00073	7.54e-22	-	-	-	-	-	-	-	-
HLDNKGNC_00074	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HLDNKGNC_00075	7.5e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HLDNKGNC_00077	2.93e-279	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLDNKGNC_00078	3.64e-313	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDNKGNC_00079	1.51e-146	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HLDNKGNC_00080	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HLDNKGNC_00081	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HLDNKGNC_00082	2.78e-272	xylR	-	-	GK	-	-	-	ROK family
HLDNKGNC_00083	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLDNKGNC_00084	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HLDNKGNC_00085	1.76e-109	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
HLDNKGNC_00087	3.38e-56	ynaF	-	-	-	-	-	-	-
HLDNKGNC_00088	7.71e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HLDNKGNC_00089	7.99e-30	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLDNKGNC_00091	3.01e-91	-	-	-	S	-	-	-	CAAX protease self-immunity
HLDNKGNC_00093	3.38e-125	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_00095	1.1e-274	-	-	-	H	-	-	-	N-terminal domain of galactosyltransferase
HLDNKGNC_00096	8.8e-242	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_00097	5.56e-154	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HLDNKGNC_00098	3.9e-119	-	-	-	M	-	-	-	Glycosyltransferase like family
HLDNKGNC_00099	9.66e-64	-	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
HLDNKGNC_00100	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HLDNKGNC_00101	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HLDNKGNC_00102	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
HLDNKGNC_00103	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HLDNKGNC_00104	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLDNKGNC_00105	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HLDNKGNC_00106	4.33e-186	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HLDNKGNC_00107	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLDNKGNC_00108	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLDNKGNC_00109	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLDNKGNC_00110	3.23e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDNKGNC_00111	4.47e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDNKGNC_00112	2.51e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLDNKGNC_00113	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLDNKGNC_00114	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDNKGNC_00115	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLDNKGNC_00116	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLDNKGNC_00117	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLDNKGNC_00118	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLDNKGNC_00119	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HLDNKGNC_00120	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLDNKGNC_00121	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLDNKGNC_00122	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HLDNKGNC_00123	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLDNKGNC_00124	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLDNKGNC_00125	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLDNKGNC_00126	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLDNKGNC_00127	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLDNKGNC_00128	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDNKGNC_00129	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLDNKGNC_00130	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLDNKGNC_00131	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLDNKGNC_00132	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLDNKGNC_00133	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLDNKGNC_00134	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLDNKGNC_00135	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLDNKGNC_00136	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLDNKGNC_00137	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLDNKGNC_00138	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLDNKGNC_00139	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLDNKGNC_00140	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLDNKGNC_00141	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLDNKGNC_00142	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLDNKGNC_00143	9.43e-233	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HLDNKGNC_00144	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLDNKGNC_00145	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLDNKGNC_00146	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLDNKGNC_00147	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLDNKGNC_00148	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HLDNKGNC_00149	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDNKGNC_00150	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLDNKGNC_00151	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HLDNKGNC_00152	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLDNKGNC_00153	4.03e-104	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLDNKGNC_00154	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLDNKGNC_00155	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLDNKGNC_00156	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLDNKGNC_00157	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLDNKGNC_00158	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HLDNKGNC_00159	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HLDNKGNC_00160	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDNKGNC_00161	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLDNKGNC_00162	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLDNKGNC_00163	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HLDNKGNC_00164	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLDNKGNC_00165	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLDNKGNC_00166	1.82e-162	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLDNKGNC_00167	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HLDNKGNC_00168	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HLDNKGNC_00169	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLDNKGNC_00170	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HLDNKGNC_00171	7.42e-255	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HLDNKGNC_00172	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HLDNKGNC_00173	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HLDNKGNC_00174	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HLDNKGNC_00175	2.7e-132	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HLDNKGNC_00176	5.64e-257	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HLDNKGNC_00177	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HLDNKGNC_00178	9.43e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLDNKGNC_00179	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00180	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HLDNKGNC_00181	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLDNKGNC_00182	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HLDNKGNC_00183	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLDNKGNC_00184	4.66e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HLDNKGNC_00185	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HLDNKGNC_00186	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLDNKGNC_00187	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HLDNKGNC_00188	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLDNKGNC_00189	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HLDNKGNC_00190	6.79e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
HLDNKGNC_00191	1.43e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLDNKGNC_00192	5.04e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLDNKGNC_00193	1.84e-197	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HLDNKGNC_00194	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00195	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLDNKGNC_00196	1.9e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLDNKGNC_00197	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HLDNKGNC_00198	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HLDNKGNC_00199	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLDNKGNC_00200	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLDNKGNC_00201	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLDNKGNC_00202	4.1e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLDNKGNC_00203	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HLDNKGNC_00204	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLDNKGNC_00205	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HLDNKGNC_00206	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_00207	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HLDNKGNC_00208	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HLDNKGNC_00209	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HLDNKGNC_00210	4.28e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HLDNKGNC_00211	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLDNKGNC_00212	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HLDNKGNC_00215	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HLDNKGNC_00216	2.28e-167	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLDNKGNC_00217	5.93e-237	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLDNKGNC_00218	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLDNKGNC_00219	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLDNKGNC_00220	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLDNKGNC_00221	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HLDNKGNC_00222	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLDNKGNC_00223	2.72e-195	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HLDNKGNC_00224	1.26e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLDNKGNC_00225	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLDNKGNC_00226	4.92e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HLDNKGNC_00227	4.4e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HLDNKGNC_00228	3.32e-205	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLDNKGNC_00229	2.2e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLDNKGNC_00230	2.17e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLDNKGNC_00231	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
HLDNKGNC_00232	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLDNKGNC_00233	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLDNKGNC_00255	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLDNKGNC_00256	4.91e-264	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLDNKGNC_00257	2.15e-237	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HLDNKGNC_00258	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLDNKGNC_00259	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLDNKGNC_00260	4.54e-54	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HLDNKGNC_00261	1.06e-259	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
HLDNKGNC_00262	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
HLDNKGNC_00263	2.42e-263	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
HLDNKGNC_00265	1.19e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
HLDNKGNC_00266	3.15e-230	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
HLDNKGNC_00267	8.28e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLDNKGNC_00268	1.15e-194	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HLDNKGNC_00269	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HLDNKGNC_00270	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HLDNKGNC_00271	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HLDNKGNC_00272	5.7e-196	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HLDNKGNC_00273	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLDNKGNC_00274	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLDNKGNC_00275	2.88e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HLDNKGNC_00276	1.53e-216	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLDNKGNC_00277	6.86e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLDNKGNC_00278	3.03e-295	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLDNKGNC_00279	7.92e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HLDNKGNC_00280	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HLDNKGNC_00281	6.96e-240	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HLDNKGNC_00282	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HLDNKGNC_00283	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLDNKGNC_00284	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HLDNKGNC_00285	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLDNKGNC_00286	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
HLDNKGNC_00288	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLDNKGNC_00289	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HLDNKGNC_00290	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HLDNKGNC_00291	4.43e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLDNKGNC_00292	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLDNKGNC_00293	1.26e-238	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HLDNKGNC_00294	1.11e-189	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HLDNKGNC_00295	5.75e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HLDNKGNC_00296	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HLDNKGNC_00297	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLDNKGNC_00298	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLDNKGNC_00299	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_00300	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HLDNKGNC_00301	4.7e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HLDNKGNC_00302	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HLDNKGNC_00303	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HLDNKGNC_00304	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HLDNKGNC_00305	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HLDNKGNC_00307	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HLDNKGNC_00308	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_00309	1.77e-201	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLDNKGNC_00310	5.56e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HLDNKGNC_00311	1.02e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_00312	1.66e-288	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLDNKGNC_00313	2.94e-166	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_00314	1.58e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HLDNKGNC_00315	4.47e-178	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_00316	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HLDNKGNC_00317	3.29e-77	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HLDNKGNC_00318	9.96e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HLDNKGNC_00319	3.82e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HLDNKGNC_00320	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HLDNKGNC_00321	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLDNKGNC_00322	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HLDNKGNC_00323	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HLDNKGNC_00324	4.43e-185	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HLDNKGNC_00325	4.75e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDNKGNC_00326	1.74e-310	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLDNKGNC_00327	2.64e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_00328	9.68e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HLDNKGNC_00329	6.43e-179	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HLDNKGNC_00330	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HLDNKGNC_00331	1.82e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLDNKGNC_00332	6.59e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HLDNKGNC_00333	1.86e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HLDNKGNC_00334	1.25e-285	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLDNKGNC_00335	6.09e-176	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HLDNKGNC_00336	6.19e-193	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HLDNKGNC_00337	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HLDNKGNC_00338	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00339	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HLDNKGNC_00340	1.61e-276	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HLDNKGNC_00341	6.78e-94	yteS	-	-	G	-	-	-	transport
HLDNKGNC_00342	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HLDNKGNC_00343	3.81e-150	yteU	-	-	S	-	-	-	Integral membrane protein
HLDNKGNC_00344	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HLDNKGNC_00345	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HLDNKGNC_00346	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HLDNKGNC_00347	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_00348	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLDNKGNC_00349	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HLDNKGNC_00350	5.66e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLDNKGNC_00351	1.28e-257	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HLDNKGNC_00352	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLDNKGNC_00353	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HLDNKGNC_00354	2.36e-218	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLDNKGNC_00355	2.48e-129	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HLDNKGNC_00356	4.92e-212	ytlQ	-	-	-	-	-	-	-
HLDNKGNC_00357	1.83e-230	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLDNKGNC_00358	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLDNKGNC_00359	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
HLDNKGNC_00360	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
HLDNKGNC_00361	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLDNKGNC_00362	7.23e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLDNKGNC_00363	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HLDNKGNC_00364	6.75e-67	ytzB	-	-	S	-	-	-	small secreted protein
HLDNKGNC_00365	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HLDNKGNC_00366	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HLDNKGNC_00367	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HLDNKGNC_00368	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HLDNKGNC_00369	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDNKGNC_00370	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLDNKGNC_00371	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLDNKGNC_00372	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLDNKGNC_00373	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HLDNKGNC_00374	3.7e-70	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HLDNKGNC_00375	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HLDNKGNC_00376	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLDNKGNC_00377	1.13e-185	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HLDNKGNC_00378	3.23e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HLDNKGNC_00379	5.13e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HLDNKGNC_00380	1.7e-149	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HLDNKGNC_00381	9.91e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HLDNKGNC_00382	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLDNKGNC_00383	2.63e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLDNKGNC_00385	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLDNKGNC_00386	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HLDNKGNC_00387	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HLDNKGNC_00388	1.2e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00389	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HLDNKGNC_00390	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLDNKGNC_00391	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLDNKGNC_00392	2.74e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLDNKGNC_00393	1.04e-287	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLDNKGNC_00394	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLDNKGNC_00395	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLDNKGNC_00396	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HLDNKGNC_00397	9.78e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLDNKGNC_00398	9.73e-230	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HLDNKGNC_00399	9.62e-111	yteJ	-	-	S	-	-	-	RDD family
HLDNKGNC_00400	4.13e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HLDNKGNC_00401	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HLDNKGNC_00402	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLDNKGNC_00403	2.19e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HLDNKGNC_00404	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLDNKGNC_00405	9.5e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HLDNKGNC_00406	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLDNKGNC_00407	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLDNKGNC_00409	1.9e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_00410	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HLDNKGNC_00411	1.95e-220	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HLDNKGNC_00412	8.07e-128	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HLDNKGNC_00413	2.06e-191	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLDNKGNC_00414	1.91e-192	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLDNKGNC_00415	7.88e-156	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_00416	1.31e-152	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_00417	5.43e-182	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLDNKGNC_00418	1.9e-231	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_00419	2.07e-60	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HLDNKGNC_00420	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_00421	2.31e-164	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HLDNKGNC_00422	1.21e-305	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HLDNKGNC_00423	6.14e-204	ytnM	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDNKGNC_00424	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HLDNKGNC_00425	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HLDNKGNC_00426	1.44e-229	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HLDNKGNC_00427	1.15e-39	-	-	-	-	-	-	-	-
HLDNKGNC_00428	5.12e-112	ytrI	-	-	-	-	-	-	-
HLDNKGNC_00429	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HLDNKGNC_00430	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLDNKGNC_00431	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HLDNKGNC_00432	2.17e-208	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLDNKGNC_00433	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HLDNKGNC_00434	6.6e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLDNKGNC_00435	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLDNKGNC_00436	4.68e-82	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HLDNKGNC_00437	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HLDNKGNC_00438	1.56e-93	ytwI	-	-	S	-	-	-	membrane
HLDNKGNC_00439	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLDNKGNC_00440	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HLDNKGNC_00441	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HLDNKGNC_00442	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_00443	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HLDNKGNC_00444	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLDNKGNC_00445	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLDNKGNC_00446	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HLDNKGNC_00447	2.82e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLDNKGNC_00448	4.54e-205	ytbE	-	-	S	-	-	-	reductase
HLDNKGNC_00449	1.12e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HLDNKGNC_00450	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00451	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLDNKGNC_00452	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HLDNKGNC_00453	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLDNKGNC_00454	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HLDNKGNC_00455	4.97e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLDNKGNC_00456	8.99e-140	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_00457	3.46e-205	ytxC	-	-	S	-	-	-	YtxC-like family
HLDNKGNC_00459	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLDNKGNC_00460	8.08e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HLDNKGNC_00461	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_00462	3.39e-167	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HLDNKGNC_00463	4.9e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLDNKGNC_00464	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLDNKGNC_00466	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLDNKGNC_00467	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLDNKGNC_00468	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLDNKGNC_00469	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
HLDNKGNC_00470	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HLDNKGNC_00471	8.77e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HLDNKGNC_00472	5.74e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HLDNKGNC_00473	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLDNKGNC_00474	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HLDNKGNC_00475	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HLDNKGNC_00476	3e-187	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HLDNKGNC_00477	1.35e-284	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HLDNKGNC_00478	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HLDNKGNC_00479	5.56e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HLDNKGNC_00480	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HLDNKGNC_00481	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HLDNKGNC_00482	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HLDNKGNC_00484	1.26e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
HLDNKGNC_00485	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HLDNKGNC_00486	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HLDNKGNC_00487	6.71e-265	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HLDNKGNC_00488	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HLDNKGNC_00489	3.13e-171	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLDNKGNC_00490	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLDNKGNC_00491	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLDNKGNC_00492	2.96e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDNKGNC_00493	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLDNKGNC_00494	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HLDNKGNC_00495	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HLDNKGNC_00496	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLDNKGNC_00497	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HLDNKGNC_00498	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLDNKGNC_00499	1.21e-130	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_00500	2.56e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HLDNKGNC_00501	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HLDNKGNC_00502	2.89e-226	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HLDNKGNC_00504	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HLDNKGNC_00505	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLDNKGNC_00506	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLDNKGNC_00507	1.54e-272	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLDNKGNC_00508	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLDNKGNC_00509	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HLDNKGNC_00510	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HLDNKGNC_00511	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HLDNKGNC_00512	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HLDNKGNC_00513	6.14e-25	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_00514	9.57e-63	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HLDNKGNC_00517	2.13e-32	-	-	-	K	ko:K07467	-	ko00000	sequence-specific DNA binding
HLDNKGNC_00523	7.37e-56	-	-	-	S	-	-	-	DNA binding
HLDNKGNC_00524	2.69e-88	-	-	-	-	-	-	-	-
HLDNKGNC_00529	3.12e-192	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HLDNKGNC_00530	3.58e-148	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HLDNKGNC_00531	1.52e-47	yqaL	-	-	L	-	-	-	DnaD domain protein
HLDNKGNC_00532	6.12e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HLDNKGNC_00535	3.16e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HLDNKGNC_00537	2.97e-26	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HLDNKGNC_00540	2.46e-129	-	-	-	H	-	-	-	C-5 cytosine-specific DNA methylase
HLDNKGNC_00544	6.46e-06	-	-	-	S	-	-	-	YopX protein
HLDNKGNC_00549	2.15e-90	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLDNKGNC_00551	1.99e-21	-	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00555	6.44e-109	yqaS	-	-	L	-	-	-	DNA packaging
HLDNKGNC_00556	1.89e-235	-	-	-	S	-	-	-	Terminase-like family
HLDNKGNC_00557	2.27e-195	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HLDNKGNC_00558	1.76e-87	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HLDNKGNC_00559	8.64e-166	-	-	-	S	-	-	-	Phage capsid family
HLDNKGNC_00561	3.46e-41	-	-	-	S	-	-	-	Phage Mu protein F like protein
HLDNKGNC_00563	6.02e-62	-	-	-	-	-	-	-	-
HLDNKGNC_00565	6.84e-40	-	-	-	-	-	-	-	-
HLDNKGNC_00566	7.19e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
HLDNKGNC_00567	1.84e-45	-	-	-	-	-	-	-	-
HLDNKGNC_00568	8.19e-19	-	-	-	-	-	-	-	-
HLDNKGNC_00569	1.78e-173	-	-	-	N	-	-	-	phage tail tape measure protein
HLDNKGNC_00570	6.22e-47	-	-	-	M	-	-	-	LysM domain
HLDNKGNC_00571	1.86e-40	-	-	-	-	-	-	-	-
HLDNKGNC_00572	3.69e-111	-	-	-	-	-	-	-	-
HLDNKGNC_00574	2.25e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HLDNKGNC_00575	1.21e-133	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
HLDNKGNC_00576	4.28e-79	-	-	-	-	-	-	-	-
HLDNKGNC_00577	2.64e-51	-	-	-	-	-	-	-	-
HLDNKGNC_00579	2.89e-17	xkdX	-	-	-	-	-	-	-
HLDNKGNC_00580	1.95e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HLDNKGNC_00581	1.58e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
HLDNKGNC_00582	6.56e-137	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HLDNKGNC_00583	4.47e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLDNKGNC_00584	3.26e-57	-	-	-	S	-	-	-	YolD-like protein
HLDNKGNC_00585	1.07e-205	-	-	-	L	-	-	-	Recombinase
HLDNKGNC_00586	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_00587	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLDNKGNC_00588	3.27e-255	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HLDNKGNC_00589	1.01e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLDNKGNC_00590	1.76e-131	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLDNKGNC_00591	7.54e-117	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HLDNKGNC_00593	2.03e-184	ysnF	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00594	6.61e-46	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HLDNKGNC_00596	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HLDNKGNC_00597	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HLDNKGNC_00598	5.55e-244	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLDNKGNC_00599	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLDNKGNC_00600	1.23e-254	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLDNKGNC_00601	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLDNKGNC_00602	3.62e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLDNKGNC_00603	1.11e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HLDNKGNC_00604	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLDNKGNC_00605	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLDNKGNC_00606	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HLDNKGNC_00607	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HLDNKGNC_00608	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLDNKGNC_00609	9.62e-116	ysxD	-	-	-	-	-	-	-
HLDNKGNC_00610	2.74e-315	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HLDNKGNC_00611	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HLDNKGNC_00612	1.8e-219	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HLDNKGNC_00613	2.49e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HLDNKGNC_00614	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HLDNKGNC_00615	1.75e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HLDNKGNC_00616	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HLDNKGNC_00617	1.09e-248	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HLDNKGNC_00618	1.53e-35	-	-	-	-	-	-	-	-
HLDNKGNC_00619	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLDNKGNC_00620	5.8e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLDNKGNC_00621	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HLDNKGNC_00622	3.36e-208	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HLDNKGNC_00623	1.73e-132	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HLDNKGNC_00624	8.35e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HLDNKGNC_00625	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HLDNKGNC_00626	1.91e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLDNKGNC_00627	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HLDNKGNC_00628	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLDNKGNC_00629	6.84e-185	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HLDNKGNC_00630	3.54e-185	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HLDNKGNC_00631	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HLDNKGNC_00632	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLDNKGNC_00633	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HLDNKGNC_00634	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLDNKGNC_00635	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HLDNKGNC_00636	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLDNKGNC_00637	1.36e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HLDNKGNC_00638	1.43e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HLDNKGNC_00639	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HLDNKGNC_00640	8.24e-291	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLDNKGNC_00641	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HLDNKGNC_00642	2.51e-202	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HLDNKGNC_00643	2.28e-272	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HLDNKGNC_00644	4.02e-216	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HLDNKGNC_00645	7.28e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLDNKGNC_00646	6.8e-162	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HLDNKGNC_00647	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HLDNKGNC_00648	4.41e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
HLDNKGNC_00650	9.45e-152	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HLDNKGNC_00651	6.51e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HLDNKGNC_00652	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
HLDNKGNC_00653	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HLDNKGNC_00654	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLDNKGNC_00655	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLDNKGNC_00656	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HLDNKGNC_00657	3.49e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLDNKGNC_00658	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLDNKGNC_00659	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HLDNKGNC_00660	2.16e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HLDNKGNC_00661	8.64e-145	yrbG	-	-	S	-	-	-	membrane
HLDNKGNC_00662	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_00663	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HLDNKGNC_00664	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLDNKGNC_00665	3.1e-112	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HLDNKGNC_00666	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HLDNKGNC_00667	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLDNKGNC_00668	2.95e-117	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLDNKGNC_00669	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLDNKGNC_00670	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLDNKGNC_00671	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HLDNKGNC_00673	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLDNKGNC_00674	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLDNKGNC_00675	3.96e-177	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HLDNKGNC_00676	2e-302	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HLDNKGNC_00677	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_00678	1.8e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HLDNKGNC_00679	1.19e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLDNKGNC_00680	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLDNKGNC_00681	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLDNKGNC_00682	3.39e-106	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00683	8.4e-42	yrzR	-	-	-	-	-	-	-
HLDNKGNC_00684	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HLDNKGNC_00685	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDNKGNC_00686	2.18e-137	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDNKGNC_00687	5.2e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLDNKGNC_00688	7.7e-169	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLDNKGNC_00689	3.07e-242	yrrI	-	-	S	-	-	-	AI-2E family transporter
HLDNKGNC_00690	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLDNKGNC_00691	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLDNKGNC_00692	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLDNKGNC_00693	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLDNKGNC_00694	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLDNKGNC_00695	1.4e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HLDNKGNC_00696	7.67e-223	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HLDNKGNC_00697	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HLDNKGNC_00698	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLDNKGNC_00699	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLDNKGNC_00700	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HLDNKGNC_00701	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HLDNKGNC_00702	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HLDNKGNC_00703	7.23e-155	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HLDNKGNC_00704	8.02e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLDNKGNC_00705	7.04e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HLDNKGNC_00706	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLDNKGNC_00707	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
HLDNKGNC_00708	4.26e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLDNKGNC_00709	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HLDNKGNC_00710	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HLDNKGNC_00712	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HLDNKGNC_00714	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HLDNKGNC_00715	2.13e-124	yrhH	-	-	Q	-	-	-	methyltransferase
HLDNKGNC_00716	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HLDNKGNC_00717	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HLDNKGNC_00718	1.49e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
HLDNKGNC_00719	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HLDNKGNC_00720	1.23e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HLDNKGNC_00721	3.34e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_00722	9.79e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
HLDNKGNC_00723	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
HLDNKGNC_00724	3.6e-316	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_00725	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HLDNKGNC_00726	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HLDNKGNC_00727	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HLDNKGNC_00728	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HLDNKGNC_00729	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HLDNKGNC_00730	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HLDNKGNC_00731	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HLDNKGNC_00732	1.61e-251	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HLDNKGNC_00733	9.08e-68	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HLDNKGNC_00734	1.46e-65	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HLDNKGNC_00735	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
HLDNKGNC_00736	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLDNKGNC_00737	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
HLDNKGNC_00738	3.45e-49	yraG	-	-	-	ko:K06440	-	ko00000	-
HLDNKGNC_00739	5.45e-86	-	-	-	E	-	-	-	Glyoxalase-like domain
HLDNKGNC_00740	1.74e-13	-	-	-	T	-	-	-	sh3 domain protein
HLDNKGNC_00741	7.72e-54	-	-	-	T	-	-	-	sh3 domain protein
HLDNKGNC_00742	2.69e-79	-	-	-	T	-	-	-	sh3 domain protein
HLDNKGNC_00743	1.35e-193	-	-	-	S	-	-	-	Alpha beta hydrolase
HLDNKGNC_00744	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_00745	5.73e-202	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HLDNKGNC_00746	1.4e-261	yraM	-	-	S	-	-	-	PrpF protein
HLDNKGNC_00747	5.13e-211	yraN	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00748	5.31e-286	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLDNKGNC_00749	2.43e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
HLDNKGNC_00750	2.14e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_00751	3.1e-168	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HLDNKGNC_00753	1.88e-159	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HLDNKGNC_00754	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLDNKGNC_00756	3.73e-240	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HLDNKGNC_00757	2.01e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HLDNKGNC_00758	1.17e-117	yrdA	-	-	S	-	-	-	DinB family
HLDNKGNC_00759	1.42e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HLDNKGNC_00760	4.27e-132	yrdC	-	-	Q	-	-	-	Isochorismatase family
HLDNKGNC_00762	1.01e-294	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLDNKGNC_00763	4.64e-44	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HLDNKGNC_00764	4.13e-104	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
HLDNKGNC_00765	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
HLDNKGNC_00766	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HLDNKGNC_00767	1.17e-290	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLDNKGNC_00768	2.33e-206	-	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HLDNKGNC_00769	3.4e-85	yodA	-	-	S	-	-	-	tautomerase
HLDNKGNC_00770	6e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HLDNKGNC_00771	2.89e-252	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HLDNKGNC_00772	7.78e-201	-	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_00773	4.91e-216	yrdR	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_00774	7.04e-23	-	-	-	S	-	-	-	YrzO-like protein
HLDNKGNC_00775	1.97e-295	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLDNKGNC_00776	6.19e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HLDNKGNC_00777	3.76e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_00778	2.06e-193	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLDNKGNC_00779	2.21e-138	yrkC	-	-	G	-	-	-	Cupin domain
HLDNKGNC_00780	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00781	1.96e-108	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
HLDNKGNC_00782	3.95e-127	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
HLDNKGNC_00783	0.000112	perX	-	-	S	-	-	-	DsrE/DsrF-like family
HLDNKGNC_00784	8.08e-261	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
HLDNKGNC_00785	1.3e-48	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HLDNKGNC_00786	5.31e-155	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDNKGNC_00787	3.13e-104	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
HLDNKGNC_00788	5.71e-126	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HLDNKGNC_00789	5.41e-134	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLDNKGNC_00790	1.34e-280	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLDNKGNC_00791	1.24e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
HLDNKGNC_00792	2.34e-302	yrkQ	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_00793	2.15e-90	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
HLDNKGNC_00794	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_00795	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HLDNKGNC_00796	9.38e-171	-	-	-	-	-	-	-	-
HLDNKGNC_00797	1.26e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HLDNKGNC_00798	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_00799	2.2e-172	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HLDNKGNC_00800	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLDNKGNC_00802	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HLDNKGNC_00803	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HLDNKGNC_00804	9.86e-200	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLDNKGNC_00805	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HLDNKGNC_00806	4.99e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLDNKGNC_00807	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HLDNKGNC_00808	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLDNKGNC_00809	9.8e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
HLDNKGNC_00810	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLDNKGNC_00811	7.77e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HLDNKGNC_00812	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HLDNKGNC_00813	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLDNKGNC_00814	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
HLDNKGNC_00815	2.35e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLDNKGNC_00816	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLDNKGNC_00817	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HLDNKGNC_00818	3.88e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HLDNKGNC_00819	8.25e-69	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HLDNKGNC_00820	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLDNKGNC_00821	9.71e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HLDNKGNC_00822	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLDNKGNC_00823	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLDNKGNC_00824	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLDNKGNC_00825	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLDNKGNC_00826	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HLDNKGNC_00827	5.63e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLDNKGNC_00828	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HLDNKGNC_00829	4.02e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HLDNKGNC_00830	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLDNKGNC_00831	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HLDNKGNC_00832	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HLDNKGNC_00833	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
HLDNKGNC_00834	6.04e-61	yqfB	-	-	-	-	-	-	-
HLDNKGNC_00835	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HLDNKGNC_00836	1.04e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HLDNKGNC_00837	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HLDNKGNC_00839	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HLDNKGNC_00840	8.68e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLDNKGNC_00841	4.75e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HLDNKGNC_00842	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HLDNKGNC_00843	2.35e-213	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLDNKGNC_00844	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
HLDNKGNC_00845	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLDNKGNC_00846	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLDNKGNC_00847	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLDNKGNC_00848	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
HLDNKGNC_00849	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLDNKGNC_00850	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HLDNKGNC_00851	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLDNKGNC_00852	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLDNKGNC_00853	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HLDNKGNC_00854	6.9e-150	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLDNKGNC_00855	9.26e-270	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLDNKGNC_00856	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HLDNKGNC_00857	4.18e-52	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HLDNKGNC_00858	2.21e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLDNKGNC_00859	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLDNKGNC_00860	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HLDNKGNC_00861	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLDNKGNC_00862	2.47e-106	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HLDNKGNC_00863	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HLDNKGNC_00864	2.04e-81	yqfX	-	-	S	-	-	-	membrane
HLDNKGNC_00865	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HLDNKGNC_00866	2.84e-63	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HLDNKGNC_00867	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HLDNKGNC_00868	4.77e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HLDNKGNC_00869	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HLDNKGNC_00870	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HLDNKGNC_00871	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HLDNKGNC_00872	5.26e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLDNKGNC_00873	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLDNKGNC_00874	8.71e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HLDNKGNC_00875	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDNKGNC_00876	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLDNKGNC_00877	6.33e-93	yqzC	-	-	S	-	-	-	YceG-like family
HLDNKGNC_00878	3.42e-68	yqzD	-	-	-	-	-	-	-
HLDNKGNC_00880	4.65e-256	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
HLDNKGNC_00881	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLDNKGNC_00882	1.05e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLDNKGNC_00883	3.38e-14	yqgO	-	-	-	-	-	-	-
HLDNKGNC_00884	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HLDNKGNC_00885	2.19e-44	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HLDNKGNC_00886	2.81e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HLDNKGNC_00887	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLDNKGNC_00888	7.16e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HLDNKGNC_00889	5.65e-258	yqgU	-	-	-	-	-	-	-
HLDNKGNC_00890	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HLDNKGNC_00891	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HLDNKGNC_00892	2.25e-157	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HLDNKGNC_00893	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HLDNKGNC_00894	1.29e-83	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HLDNKGNC_00896	6.12e-193	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLDNKGNC_00897	1.42e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLDNKGNC_00898	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HLDNKGNC_00899	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HLDNKGNC_00900	5.23e-256	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLDNKGNC_00901	1.06e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HLDNKGNC_00902	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HLDNKGNC_00903	9.32e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
HLDNKGNC_00904	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HLDNKGNC_00905	1.01e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HLDNKGNC_00906	7.63e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HLDNKGNC_00907	4.9e-37	yqzE	-	-	S	-	-	-	YqzE-like protein
HLDNKGNC_00908	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HLDNKGNC_00909	1.14e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
HLDNKGNC_00910	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HLDNKGNC_00911	4.28e-180	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HLDNKGNC_00912	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HLDNKGNC_00913	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HLDNKGNC_00914	5.29e-196	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HLDNKGNC_00915	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLDNKGNC_00916	3.17e-260	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HLDNKGNC_00917	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLDNKGNC_00918	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLDNKGNC_00919	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HLDNKGNC_00920	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HLDNKGNC_00921	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HLDNKGNC_00922	5.75e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HLDNKGNC_00923	5.18e-81	yqhP	-	-	-	-	-	-	-
HLDNKGNC_00924	2.17e-179	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HLDNKGNC_00925	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HLDNKGNC_00926	3.34e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HLDNKGNC_00927	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HLDNKGNC_00928	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLDNKGNC_00929	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HLDNKGNC_00930	4.75e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HLDNKGNC_00931	5.69e-111	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HLDNKGNC_00932	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HLDNKGNC_00933	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HLDNKGNC_00934	1.8e-255	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HLDNKGNC_00935	4.27e-130	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HLDNKGNC_00936	8.86e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HLDNKGNC_00937	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HLDNKGNC_00938	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLDNKGNC_00939	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HLDNKGNC_00940	1.65e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00941	1.38e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLDNKGNC_00942	4.34e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLDNKGNC_00943	2.21e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDNKGNC_00944	1.81e-50	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLDNKGNC_00945	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLDNKGNC_00946	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLDNKGNC_00947	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HLDNKGNC_00948	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLDNKGNC_00949	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLDNKGNC_00950	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HLDNKGNC_00951	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HLDNKGNC_00953	4.47e-270	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HLDNKGNC_00954	4.74e-37	-	-	-	-	-	-	-	-
HLDNKGNC_00955	2.7e-137	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HLDNKGNC_00956	1.23e-170	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLDNKGNC_00957	6.65e-280	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLDNKGNC_00958	1.98e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HLDNKGNC_00959	1.36e-265	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HLDNKGNC_00960	2.63e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLDNKGNC_00961	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HLDNKGNC_00962	1.52e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HLDNKGNC_00963	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HLDNKGNC_00964	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HLDNKGNC_00965	3.02e-199	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HLDNKGNC_00966	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLDNKGNC_00967	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HLDNKGNC_00968	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLDNKGNC_00969	2.73e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLDNKGNC_00970	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLDNKGNC_00971	1.6e-289	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLDNKGNC_00972	7.45e-194	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
HLDNKGNC_00973	6.23e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_00974	2.35e-211	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLDNKGNC_00975	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HLDNKGNC_00976	8.29e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLDNKGNC_00977	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLDNKGNC_00978	3.66e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLDNKGNC_00979	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HLDNKGNC_00980	2.82e-127	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_00982	6.89e-97	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HLDNKGNC_00983	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLDNKGNC_00984	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HLDNKGNC_00985	1.99e-180	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HLDNKGNC_00986	1.79e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDNKGNC_00987	1.77e-32	yqzJ	-	-	-	-	-	-	-
HLDNKGNC_00988	9.1e-300	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLDNKGNC_00989	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLDNKGNC_00990	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLDNKGNC_00991	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLDNKGNC_00992	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLDNKGNC_00993	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLDNKGNC_00994	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HLDNKGNC_00995	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HLDNKGNC_00996	6.56e-188	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLDNKGNC_00997	1.33e-228	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLDNKGNC_00998	1.62e-183	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_00999	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HLDNKGNC_01000	6.6e-229	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLDNKGNC_01001	7.43e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_01003	1.68e-288	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
HLDNKGNC_01005	2.23e-301	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLDNKGNC_01006	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
HLDNKGNC_01007	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HLDNKGNC_01008	5.51e-79	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HLDNKGNC_01009	1.37e-249	yqkA	-	-	K	-	-	-	GrpB protein
HLDNKGNC_01010	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HLDNKGNC_01011	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HLDNKGNC_01012	6.55e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HLDNKGNC_01013	4.65e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HLDNKGNC_01014	4.4e-216	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HLDNKGNC_01015	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HLDNKGNC_01016	9.6e-119	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HLDNKGNC_01017	1.19e-279	yqxK	-	-	L	-	-	-	DNA helicase
HLDNKGNC_01018	7.5e-76	ansR	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01019	7.23e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HLDNKGNC_01020	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HLDNKGNC_01021	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HLDNKGNC_01022	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HLDNKGNC_01023	3.08e-43	yqkK	-	-	-	-	-	-	-
HLDNKGNC_01024	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HLDNKGNC_01025	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLDNKGNC_01026	2.25e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HLDNKGNC_01027	7.9e-214	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLDNKGNC_01028	6.52e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLDNKGNC_01029	3.98e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HLDNKGNC_01030	2.89e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLDNKGNC_01031	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HLDNKGNC_01032	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HLDNKGNC_01033	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_01034	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HLDNKGNC_01035	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HLDNKGNC_01036	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HLDNKGNC_01037	1.42e-244	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HLDNKGNC_01038	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HLDNKGNC_01039	5.31e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HLDNKGNC_01040	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HLDNKGNC_01041	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLDNKGNC_01042	8.93e-192	ypuA	-	-	S	-	-	-	Secreted protein
HLDNKGNC_01043	1.23e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLDNKGNC_01048	2.61e-34	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLDNKGNC_01050	6.1e-11	-	-	-	M	-	-	-	Domain of Unknown Function (DUF1259)
HLDNKGNC_01051	3.82e-09	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_01053	1.28e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HLDNKGNC_01054	3.39e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLDNKGNC_01055	5.98e-72	ypuD	-	-	-	-	-	-	-
HLDNKGNC_01056	8.41e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLDNKGNC_01057	1.24e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HLDNKGNC_01058	1.27e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLDNKGNC_01059	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLDNKGNC_01060	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_01061	4.87e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HLDNKGNC_01062	1.55e-166	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLDNKGNC_01063	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLDNKGNC_01064	6.13e-128	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HLDNKGNC_01065	9.67e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLDNKGNC_01066	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HLDNKGNC_01067	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HLDNKGNC_01068	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLDNKGNC_01069	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HLDNKGNC_01070	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HLDNKGNC_01071	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HLDNKGNC_01072	6.88e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_01073	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_01074	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_01075	1.95e-250	rsiX	-	-	-	-	-	-	-
HLDNKGNC_01076	4.59e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLDNKGNC_01077	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDNKGNC_01078	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLDNKGNC_01079	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HLDNKGNC_01080	2.31e-257	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HLDNKGNC_01081	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLDNKGNC_01082	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HLDNKGNC_01083	1.44e-123	ypbE	-	-	M	-	-	-	Lysin motif
HLDNKGNC_01084	8.23e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HLDNKGNC_01085	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLDNKGNC_01086	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLDNKGNC_01087	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLDNKGNC_01088	6.04e-223	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HLDNKGNC_01089	1.02e-152	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HLDNKGNC_01090	6.93e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HLDNKGNC_01091	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HLDNKGNC_01092	4.63e-144	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HLDNKGNC_01093	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HLDNKGNC_01094	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLDNKGNC_01095	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLDNKGNC_01096	5.67e-236	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLDNKGNC_01097	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
HLDNKGNC_01098	2.73e-134	yphA	-	-	-	-	-	-	-
HLDNKGNC_01099	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
HLDNKGNC_01100	1.45e-38	ypzH	-	-	-	-	-	-	-
HLDNKGNC_01101	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLDNKGNC_01102	2.2e-231	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLDNKGNC_01103	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HLDNKGNC_01104	1.5e-176	yphF	-	-	-	-	-	-	-
HLDNKGNC_01105	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HLDNKGNC_01106	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDNKGNC_01107	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HLDNKGNC_01108	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HLDNKGNC_01109	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HLDNKGNC_01110	1.1e-168	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLDNKGNC_01111	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLDNKGNC_01112	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HLDNKGNC_01113	3.03e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HLDNKGNC_01114	2.05e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLDNKGNC_01115	2.72e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLDNKGNC_01116	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HLDNKGNC_01117	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLDNKGNC_01118	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLDNKGNC_01119	1.25e-146	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HLDNKGNC_01120	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HLDNKGNC_01121	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLDNKGNC_01122	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLDNKGNC_01123	6.39e-259	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLDNKGNC_01124	2e-263	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HLDNKGNC_01125	4.03e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLDNKGNC_01126	3.41e-295	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLDNKGNC_01127	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HLDNKGNC_01128	1.86e-98	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HLDNKGNC_01129	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HLDNKGNC_01130	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HLDNKGNC_01131	3.31e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HLDNKGNC_01132	1.63e-125	ypjA	-	-	S	-	-	-	membrane
HLDNKGNC_01133	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
HLDNKGNC_01134	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLDNKGNC_01135	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HLDNKGNC_01136	8.04e-188	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLDNKGNC_01137	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HLDNKGNC_01138	1.56e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HLDNKGNC_01139	1.16e-265	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HLDNKGNC_01140	4.5e-280	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLDNKGNC_01141	1.39e-233	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLDNKGNC_01142	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HLDNKGNC_01143	5.47e-200	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HLDNKGNC_01144	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HLDNKGNC_01145	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLDNKGNC_01146	6.21e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HLDNKGNC_01147	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01148	1.25e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HLDNKGNC_01149	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HLDNKGNC_01150	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HLDNKGNC_01151	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLDNKGNC_01152	1.17e-120	ypoC	-	-	-	-	-	-	-
HLDNKGNC_01153	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLDNKGNC_01154	3.2e-150	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLDNKGNC_01155	5.94e-237	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HLDNKGNC_01157	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HLDNKGNC_01158	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
HLDNKGNC_01159	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
HLDNKGNC_01160	5.06e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLDNKGNC_01161	3.73e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HLDNKGNC_01162	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HLDNKGNC_01163	1.7e-299	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HLDNKGNC_01164	2.31e-128	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLDNKGNC_01165	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLDNKGNC_01166	1.01e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLDNKGNC_01167	9.72e-66	yqgA	-	-	-	-	-	-	-
HLDNKGNC_01169	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HLDNKGNC_01170	1.68e-178	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_01171	1.47e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HLDNKGNC_01172	1.19e-234	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HLDNKGNC_01173	6.95e-238	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HLDNKGNC_01174	1.03e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HLDNKGNC_01175	4.09e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HLDNKGNC_01176	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HLDNKGNC_01177	2.34e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLDNKGNC_01178	1.22e-77	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HLDNKGNC_01180	1.4e-39	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDNKGNC_01183	2.45e-183	-	-	-	S	-	-	-	N-methyltransferase activity
HLDNKGNC_01190	7.16e-280	-	-	-	-	-	-	-	-
HLDNKGNC_01194	1.45e-55	-	-	-	-	-	-	-	-
HLDNKGNC_01195	7.41e-86	-	-	-	-	-	-	-	-
HLDNKGNC_01196	2.15e-37	-	-	-	-	-	-	-	-
HLDNKGNC_01197	5.5e-57	-	-	-	-	-	-	-	-
HLDNKGNC_01199	2.68e-69	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
HLDNKGNC_01200	1.64e-97	-	-	-	L	-	-	-	Resolvase, N terminal domain
HLDNKGNC_01201	0.0	-	-	-	S	-	-	-	TIGRFAM Phage
HLDNKGNC_01202	7.97e-207	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HLDNKGNC_01203	4.64e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HLDNKGNC_01204	2.14e-117	-	-	-	S	-	-	-	P22 coat protein-protein 5 domain protein
HLDNKGNC_01205	9.92e-38	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLDNKGNC_01207	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HLDNKGNC_01208	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
HLDNKGNC_01209	2.11e-05	-	-	-	-	-	-	-	-
HLDNKGNC_01210	1.88e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HLDNKGNC_01211	4.68e-302	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HLDNKGNC_01212	4.03e-56	-	-	-	-	-	-	-	-
HLDNKGNC_01214	4.31e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDNKGNC_01218	6.83e-64	-	-	-	L	-	-	-	Recombinase
HLDNKGNC_01219	1.2e-200	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HLDNKGNC_01220	4.36e-264	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HLDNKGNC_01221	3.33e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HLDNKGNC_01223	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HLDNKGNC_01224	1.17e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HLDNKGNC_01225	1.08e-11	-	-	-	-	-	-	-	-
HLDNKGNC_01226	1.31e-212	ypcP	-	-	L	-	-	-	5'3' exonuclease
HLDNKGNC_01227	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
HLDNKGNC_01228	5.37e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HLDNKGNC_01229	3.98e-137	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HLDNKGNC_01230	1.1e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HLDNKGNC_01231	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
HLDNKGNC_01232	1.5e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HLDNKGNC_01233	1.17e-22	degR	-	-	-	-	-	-	-
HLDNKGNC_01234	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HLDNKGNC_01235	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HLDNKGNC_01237	1.28e-226	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLDNKGNC_01238	3.13e-114	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HLDNKGNC_01239	1.15e-138	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HLDNKGNC_01240	5.71e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HLDNKGNC_01241	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HLDNKGNC_01242	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HLDNKGNC_01243	4.15e-185	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HLDNKGNC_01244	3.47e-148	ypjP	-	-	S	-	-	-	YpjP-like protein
HLDNKGNC_01245	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HLDNKGNC_01246	1.92e-198	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLDNKGNC_01247	3.9e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLDNKGNC_01248	1.11e-141	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLDNKGNC_01249	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HLDNKGNC_01250	1.91e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01251	3.64e-310	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLDNKGNC_01252	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HLDNKGNC_01253	1.6e-139	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HLDNKGNC_01254	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLDNKGNC_01255	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01256	2.13e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
HLDNKGNC_01257	4.95e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
HLDNKGNC_01258	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
HLDNKGNC_01259	8.41e-134	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLDNKGNC_01260	4.13e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLDNKGNC_01261	5.51e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HLDNKGNC_01262	5.44e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HLDNKGNC_01263	6.33e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HLDNKGNC_01264	7.6e-84	cgeA	-	-	-	ko:K06319	-	ko00000	-
HLDNKGNC_01265	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
HLDNKGNC_01266	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HLDNKGNC_01267	6.89e-185	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HLDNKGNC_01269	9.36e-317	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLDNKGNC_01270	2.8e-160	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLDNKGNC_01271	7.76e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLDNKGNC_01272	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HLDNKGNC_01273	8.39e-194	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HLDNKGNC_01274	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HLDNKGNC_01275	1.4e-62	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HLDNKGNC_01276	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLDNKGNC_01277	1.29e-159	yodN	-	-	-	-	-	-	-
HLDNKGNC_01279	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
HLDNKGNC_01280	9.47e-137	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HLDNKGNC_01281	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
HLDNKGNC_01282	2.08e-12	-	-	-	-	-	-	-	-
HLDNKGNC_01283	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HLDNKGNC_01284	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HLDNKGNC_01285	2.93e-42	yodI	-	-	-	-	-	-	-
HLDNKGNC_01286	3.69e-167	yodH	-	-	Q	-	-	-	Methyltransferase
HLDNKGNC_01287	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLDNKGNC_01288	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDNKGNC_01289	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HLDNKGNC_01290	2.78e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLDNKGNC_01291	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HLDNKGNC_01292	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
HLDNKGNC_01293	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
HLDNKGNC_01294	1.1e-81	iolK	-	-	S	-	-	-	tautomerase
HLDNKGNC_01295	3.23e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HLDNKGNC_01296	3.22e-13	-	-	-	-	-	-	-	-
HLDNKGNC_01297	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HLDNKGNC_01298	7.8e-206	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HLDNKGNC_01299	1.85e-58	-	-	-	-	-	-	-	-
HLDNKGNC_01300	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HLDNKGNC_01301	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HLDNKGNC_01302	2.49e-194	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLDNKGNC_01303	2.4e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HLDNKGNC_01305	3.54e-140	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLDNKGNC_01306	1.13e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HLDNKGNC_01307	2.32e-264	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLDNKGNC_01308	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HLDNKGNC_01309	3.82e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HLDNKGNC_01310	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HLDNKGNC_01311	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HLDNKGNC_01312	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HLDNKGNC_01313	3.31e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HLDNKGNC_01314	6.18e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLDNKGNC_01315	2.26e-210	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HLDNKGNC_01316	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HLDNKGNC_01317	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLDNKGNC_01318	1.91e-42	yozC	-	-	-	-	-	-	-
HLDNKGNC_01319	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
HLDNKGNC_01320	1.83e-49	yocN	-	-	-	-	-	-	-
HLDNKGNC_01321	2.94e-55	yozN	-	-	-	-	-	-	-
HLDNKGNC_01322	6.6e-115	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLDNKGNC_01323	5.79e-43	-	-	-	-	-	-	-	-
HLDNKGNC_01324	3.02e-70	yocL	-	-	-	-	-	-	-
HLDNKGNC_01325	4.07e-107	yocK	-	-	T	-	-	-	general stress protein
HLDNKGNC_01326	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLDNKGNC_01327	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLDNKGNC_01328	2.89e-175	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HLDNKGNC_01329	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_01330	2.37e-250	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_01331	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HLDNKGNC_01332	1.29e-214	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HLDNKGNC_01333	5.16e-120	yocC	-	-	-	-	-	-	-
HLDNKGNC_01334	2.6e-185	-	-	-	-	-	-	-	-
HLDNKGNC_01335	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HLDNKGNC_01336	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLDNKGNC_01337	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HLDNKGNC_01338	6.8e-117	yobW	-	-	-	-	-	-	-
HLDNKGNC_01339	7.68e-225	yobV	-	-	K	-	-	-	WYL domain
HLDNKGNC_01340	1.49e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HLDNKGNC_01341	5.46e-169	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLDNKGNC_01342	4.91e-124	yobS	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01343	2.81e-178	-	-	-	J	-	-	-	FR47-like protein
HLDNKGNC_01344	6.36e-172	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLDNKGNC_01345	1.49e-70	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HLDNKGNC_01346	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HLDNKGNC_01347	2.3e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HLDNKGNC_01348	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HLDNKGNC_01349	2.24e-110	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HLDNKGNC_01350	1.09e-134	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLDNKGNC_01351	0.0	aga	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha-galactosidase
HLDNKGNC_01352	2.68e-141	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_01353	1.25e-127	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HLDNKGNC_01354	5.09e-53	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLDNKGNC_01356	1.23e-272	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HLDNKGNC_01357	5.18e-166	-	-	-	K	-	-	-	Bacterial regulatory proteins, lacI family
HLDNKGNC_01358	3.67e-220	-	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HLDNKGNC_01359	2.71e-29	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLDNKGNC_01360	1.48e-30	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLDNKGNC_01361	7.8e-21	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HLDNKGNC_01362	3.19e-25	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HLDNKGNC_01363	4.99e-08	-	-	-	K	-	-	-	Helix-turn-helix
HLDNKGNC_01364	6.27e-51	-	-	-	S	-	-	-	TM2 domain
HLDNKGNC_01365	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HLDNKGNC_01366	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HLDNKGNC_01370	9.93e-213	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HLDNKGNC_01371	1.3e-151	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HLDNKGNC_01372	3.26e-101	yoaW	-	-	-	-	-	-	-
HLDNKGNC_01373	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_01374	9.47e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
HLDNKGNC_01375	3.84e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HLDNKGNC_01376	6.07e-49	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01377	2.65e-97	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HLDNKGNC_01378	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
HLDNKGNC_01379	6.51e-114	-	-	-	-	-	-	-	-
HLDNKGNC_01380	1.49e-87	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HLDNKGNC_01381	9.48e-188	yoaP	-	-	K	-	-	-	YoaP-like
HLDNKGNC_01383	1.95e-296	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HLDNKGNC_01386	3.43e-169	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLDNKGNC_01387	2.89e-252	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
HLDNKGNC_01388	4.22e-144	yoaK	-	-	S	-	-	-	Membrane
HLDNKGNC_01389	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
HLDNKGNC_01390	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HLDNKGNC_01391	1.56e-315	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HLDNKGNC_01392	2.99e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HLDNKGNC_01393	1.46e-19	-	-	-	-	-	-	-	-
HLDNKGNC_01395	7.24e-45	yoaF	-	-	-	-	-	-	-
HLDNKGNC_01396	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLDNKGNC_01397	1.12e-232	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDNKGNC_01398	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HLDNKGNC_01399	6.41e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HLDNKGNC_01400	1.1e-120	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLDNKGNC_01401	1.62e-160	yoxB	-	-	-	-	-	-	-
HLDNKGNC_01402	4.86e-54	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HLDNKGNC_01403	9.27e-159	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_01404	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HLDNKGNC_01405	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLDNKGNC_01406	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLDNKGNC_01407	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01408	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HLDNKGNC_01409	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HLDNKGNC_01410	9.84e-236	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HLDNKGNC_01411	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01412	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HLDNKGNC_01413	4.71e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HLDNKGNC_01414	3.26e-124	-	-	-	L	-	-	-	Integrase
HLDNKGNC_01416	7.14e-128	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HLDNKGNC_01417	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
HLDNKGNC_01418	3.06e-237	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLDNKGNC_01419	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLDNKGNC_01421	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HLDNKGNC_01422	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
HLDNKGNC_01423	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HLDNKGNC_01424	8.36e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HLDNKGNC_01425	9.35e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HLDNKGNC_01426	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
HLDNKGNC_01427	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HLDNKGNC_01428	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HLDNKGNC_01429	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HLDNKGNC_01430	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HLDNKGNC_01431	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_01432	1.73e-48	yfhS	-	-	-	-	-	-	-
HLDNKGNC_01433	5.7e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HLDNKGNC_01434	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HLDNKGNC_01435	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLDNKGNC_01436	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_01437	2.28e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HLDNKGNC_01438	5.4e-67	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HLDNKGNC_01439	1.91e-114	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HLDNKGNC_01440	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
HLDNKGNC_01441	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HLDNKGNC_01442	2.01e-267	yfhI	-	-	EGP	-	-	-	-transporter
HLDNKGNC_01443	7.62e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HLDNKGNC_01444	3.25e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HLDNKGNC_01445	1.54e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HLDNKGNC_01447	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
HLDNKGNC_01448	1.66e-137	yfhC	-	-	C	-	-	-	nitroreductase
HLDNKGNC_01449	7.61e-215	yfhB	-	-	S	-	-	-	PhzF family
HLDNKGNC_01450	2.11e-228	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_01451	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_01452	1.9e-231	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLDNKGNC_01453	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLDNKGNC_01454	1.27e-104	yfiV	-	-	K	-	-	-	transcriptional
HLDNKGNC_01455	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HLDNKGNC_01456	9.43e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HLDNKGNC_01457	6.57e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HLDNKGNC_01458	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLDNKGNC_01459	7.71e-128	padR	-	-	K	-	-	-	transcriptional
HLDNKGNC_01460	3.82e-88	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_01461	6.64e-260	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HLDNKGNC_01462	3.08e-266	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLDNKGNC_01463	7.89e-217	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_01464	6.07e-146	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HLDNKGNC_01465	5.09e-274	baeS	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_01467	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HLDNKGNC_01468	3.34e-83	yfiD3	-	-	S	-	-	-	DoxX
HLDNKGNC_01469	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLDNKGNC_01470	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLDNKGNC_01471	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
HLDNKGNC_01472	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_01473	5.03e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HLDNKGNC_01474	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLDNKGNC_01475	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
HLDNKGNC_01476	2.76e-270	yfjB	-	-	-	-	-	-	-
HLDNKGNC_01477	4.15e-184	yfjC	-	-	-	-	-	-	-
HLDNKGNC_01478	7.1e-130	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
HLDNKGNC_01479	9.18e-102	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
HLDNKGNC_01480	7.42e-75	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
HLDNKGNC_01481	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HLDNKGNC_01482	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HLDNKGNC_01483	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLDNKGNC_01484	9.43e-262	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLDNKGNC_01485	5.32e-242	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLDNKGNC_01486	7.88e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLDNKGNC_01488	1.07e-107	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLDNKGNC_01489	4.72e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLDNKGNC_01490	5.9e-57	-	-	-	S	-	-	-	YfzA-like protein
HLDNKGNC_01491	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDNKGNC_01492	8.87e-211	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLDNKGNC_01493	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HLDNKGNC_01494	4.62e-192	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HLDNKGNC_01495	7.24e-198	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HLDNKGNC_01496	3.26e-36	yfjT	-	-	-	-	-	-	-
HLDNKGNC_01497	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
HLDNKGNC_01498	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HLDNKGNC_01499	1.5e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
HLDNKGNC_01500	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HLDNKGNC_01501	1.82e-276	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_01502	1.64e-12	-	-	-	-	-	-	-	-
HLDNKGNC_01503	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLDNKGNC_01504	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
HLDNKGNC_01505	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDNKGNC_01506	7.27e-42	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HLDNKGNC_01507	2.53e-265	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_01508	1.29e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HLDNKGNC_01509	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLDNKGNC_01510	5.27e-161	frp	-	-	C	-	-	-	nitroreductase
HLDNKGNC_01511	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HLDNKGNC_01512	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLDNKGNC_01513	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_01514	0.0	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HLDNKGNC_01515	2.28e-271	yfkR	-	-	S	ko:K06297,ko:K06308	-	ko00000	spore germination
HLDNKGNC_01517	2.1e-247	yfkT	-	-	E	ko:K06309	-	ko00000	Spore germination protein
HLDNKGNC_01518	2.4e-55	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HLDNKGNC_01519	4.03e-228	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HLDNKGNC_01520	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HLDNKGNC_01521	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLDNKGNC_01522	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HLDNKGNC_01523	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HLDNKGNC_01524	1.21e-61	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HLDNKGNC_01525	6.9e-27	yflI	-	-	-	-	-	-	-
HLDNKGNC_01526	1.1e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HLDNKGNC_01527	1.39e-156	yflK	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01528	2.54e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLDNKGNC_01529	1.95e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HLDNKGNC_01530	4.01e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HLDNKGNC_01531	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLDNKGNC_01532	5.66e-230	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HLDNKGNC_01533	3.96e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLDNKGNC_01534	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLDNKGNC_01535	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLDNKGNC_01536	1.42e-306	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HLDNKGNC_01537	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HLDNKGNC_01538	8.93e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HLDNKGNC_01539	4.77e-220	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HLDNKGNC_01540	4.72e-220	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_01541	2.1e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_01542	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLDNKGNC_01543	1.64e-239	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HLDNKGNC_01544	1.94e-100	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HLDNKGNC_01545	2.95e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HLDNKGNC_01546	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLDNKGNC_01547	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HLDNKGNC_01548	5.04e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HLDNKGNC_01549	3.09e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HLDNKGNC_01550	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLDNKGNC_01551	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
HLDNKGNC_01552	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLDNKGNC_01553	3.41e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HLDNKGNC_01554	7.44e-168	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLDNKGNC_01555	5.1e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_01556	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HLDNKGNC_01557	6.98e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HLDNKGNC_01558	1.9e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HLDNKGNC_01559	8.45e-238	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HLDNKGNC_01560	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HLDNKGNC_01561	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HLDNKGNC_01562	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HLDNKGNC_01563	4.11e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HLDNKGNC_01564	9.87e-173	-	-	-	M	-	-	-	Membrane
HLDNKGNC_01565	9.88e-263	yetM	-	-	CH	-	-	-	FAD binding domain
HLDNKGNC_01566	1.12e-115	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_01567	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLDNKGNC_01568	5.41e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HLDNKGNC_01569	3.69e-181	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLDNKGNC_01570	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_01571	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HLDNKGNC_01572	3.66e-157	yetF	-	-	S	-	-	-	membrane
HLDNKGNC_01573	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HLDNKGNC_01574	1.11e-208	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_01575	1.96e-225	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HLDNKGNC_01576	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLDNKGNC_01577	0.0	yetA	-	-	-	-	-	-	-
HLDNKGNC_01578	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HLDNKGNC_01579	2.62e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLDNKGNC_01580	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HLDNKGNC_01581	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HLDNKGNC_01582	4.02e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HLDNKGNC_01583	1.07e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
HLDNKGNC_01584	1.82e-164	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLDNKGNC_01585	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01586	2.2e-251	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HLDNKGNC_01587	2.43e-208	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_01588	2.02e-218	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_01589	4.82e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HLDNKGNC_01590	1.98e-257	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HLDNKGNC_01591	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_01592	1.04e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
HLDNKGNC_01594	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLDNKGNC_01595	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HLDNKGNC_01596	9.4e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HLDNKGNC_01597	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HLDNKGNC_01598	7.09e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
HLDNKGNC_01599	3.92e-104	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
HLDNKGNC_01600	2.85e-129	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01602	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HLDNKGNC_01604	2.46e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HLDNKGNC_01605	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
HLDNKGNC_01606	3.52e-71	-	-	-	-	-	-	-	-
HLDNKGNC_01607	3.79e-229	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
HLDNKGNC_01608	8.28e-228	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HLDNKGNC_01609	1.89e-51	-	-	-	S	-	-	-	Immunity protein 22
HLDNKGNC_01611	9.11e-124	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLDNKGNC_01613	9.72e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF1998)
HLDNKGNC_01614	0.0	-	-	-	L	-	-	-	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HLDNKGNC_01615	5.73e-59	-	-	-	-	-	-	-	-
HLDNKGNC_01619	8.7e-124	-	-	-	-	-	-	-	-
HLDNKGNC_01620	8.68e-60	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HLDNKGNC_01621	2.31e-194	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HLDNKGNC_01622	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLDNKGNC_01623	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLDNKGNC_01624	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLDNKGNC_01625	1.94e-191	yerO	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01626	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDNKGNC_01627	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLDNKGNC_01628	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLDNKGNC_01629	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDNKGNC_01630	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HLDNKGNC_01631	6.02e-251	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HLDNKGNC_01632	1.39e-278	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HLDNKGNC_01633	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLDNKGNC_01634	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLDNKGNC_01635	1.82e-160	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HLDNKGNC_01636	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HLDNKGNC_01637	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01638	1.93e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HLDNKGNC_01639	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HLDNKGNC_01640	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HLDNKGNC_01641	2.13e-294	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HLDNKGNC_01642	1.06e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HLDNKGNC_01643	5.69e-298	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLDNKGNC_01644	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLDNKGNC_01645	8.88e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLDNKGNC_01646	1.71e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLDNKGNC_01647	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLDNKGNC_01648	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDNKGNC_01649	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDNKGNC_01650	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLDNKGNC_01651	2.04e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLDNKGNC_01652	9.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLDNKGNC_01653	3.66e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLDNKGNC_01654	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLDNKGNC_01655	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
HLDNKGNC_01656	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HLDNKGNC_01658	5.85e-165	yebC	-	-	M	-	-	-	Membrane
HLDNKGNC_01659	8.05e-282	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLDNKGNC_01660	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLDNKGNC_01661	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HLDNKGNC_01662	1.25e-282	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HLDNKGNC_01663	1.68e-227	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HLDNKGNC_01664	2.49e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLDNKGNC_01665	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_01666	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HLDNKGNC_01667	1.96e-226	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
HLDNKGNC_01668	1.25e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HLDNKGNC_01669	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HLDNKGNC_01671	4.44e-205	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HLDNKGNC_01672	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
HLDNKGNC_01673	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HLDNKGNC_01674	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDNKGNC_01675	1.37e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
HLDNKGNC_01676	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HLDNKGNC_01677	8.58e-172	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HLDNKGNC_01678	8.57e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLDNKGNC_01679	6.25e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HLDNKGNC_01680	4.24e-221	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLDNKGNC_01681	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HLDNKGNC_01682	3.55e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HLDNKGNC_01683	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HLDNKGNC_01684	5.53e-175	-	-	-	-	-	-	-	-
HLDNKGNC_01685	1.17e-148	-	-	-	-	-	-	-	-
HLDNKGNC_01687	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLDNKGNC_01688	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLDNKGNC_01689	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLDNKGNC_01690	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HLDNKGNC_01691	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLDNKGNC_01692	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLDNKGNC_01693	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLDNKGNC_01694	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLDNKGNC_01695	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HLDNKGNC_01696	1.1e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLDNKGNC_01697	1.71e-109	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLDNKGNC_01698	1.76e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HLDNKGNC_01699	7.42e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HLDNKGNC_01700	3.67e-229	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HLDNKGNC_01703	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HLDNKGNC_01704	2.1e-152	xkdP	-	-	S	-	-	-	Lysin motif
HLDNKGNC_01705	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
HLDNKGNC_01706	6.14e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HLDNKGNC_01707	2.69e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HLDNKGNC_01708	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLDNKGNC_01709	7.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HLDNKGNC_01710	3.64e-55	-	-	-	-	-	-	-	-
HLDNKGNC_01711	1e-223	-	-	-	-	-	-	-	-
HLDNKGNC_01712	1.68e-55	xkdW	-	-	S	-	-	-	XkdW protein
HLDNKGNC_01713	4.47e-31	xkdX	-	-	-	-	-	-	-
HLDNKGNC_01714	2.31e-193	xepA	-	-	-	-	-	-	-
HLDNKGNC_01715	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HLDNKGNC_01716	3.31e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
HLDNKGNC_01717	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HLDNKGNC_01719	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HLDNKGNC_01720	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HLDNKGNC_01721	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HLDNKGNC_01722	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HLDNKGNC_01723	2.21e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLDNKGNC_01724	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLDNKGNC_01725	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLDNKGNC_01726	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_01728	8.43e-285	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLDNKGNC_01729	1.22e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
HLDNKGNC_01730	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HLDNKGNC_01731	2.78e-203	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_01732	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_01733	1.35e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_01734	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLDNKGNC_01736	7.89e-224	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HLDNKGNC_01737	5.65e-256	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLDNKGNC_01738	2.08e-209	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLDNKGNC_01739	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_01740	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HLDNKGNC_01741	1.78e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
HLDNKGNC_01742	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HLDNKGNC_01743	2.34e-283	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HLDNKGNC_01744	9.93e-15	-	-	-	-	-	-	-	-
HLDNKGNC_01745	6.55e-166	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLDNKGNC_01746	3.57e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HLDNKGNC_01747	1.16e-124	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLDNKGNC_01748	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HLDNKGNC_01749	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HLDNKGNC_01750	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HLDNKGNC_01751	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLDNKGNC_01752	3.23e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLDNKGNC_01754	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HLDNKGNC_01755	1.42e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HLDNKGNC_01756	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HLDNKGNC_01757	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HLDNKGNC_01758	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLDNKGNC_01759	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLDNKGNC_01760	8.04e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLDNKGNC_01761	3.12e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLDNKGNC_01762	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_01763	8.05e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLDNKGNC_01764	1.16e-140	ykoF	-	-	S	-	-	-	YKOF-related Family
HLDNKGNC_01765	1.44e-157	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_01766	3.35e-304	ykoH	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_01767	1.31e-143	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLDNKGNC_01768	1.07e-110	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLDNKGNC_01769	1.45e-08	-	-	-	-	-	-	-	-
HLDNKGNC_01771	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HLDNKGNC_01772	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
HLDNKGNC_01773	1.63e-25	-	-	-	-	-	-	-	-
HLDNKGNC_01774	3.04e-36	ykoL	-	-	-	-	-	-	-
HLDNKGNC_01775	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HLDNKGNC_01776	1.82e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HLDNKGNC_01777	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HLDNKGNC_01778	4.35e-198	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLDNKGNC_01779	0.0	ykoS	-	-	-	-	-	-	-
HLDNKGNC_01780	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_01781	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HLDNKGNC_01782	1.25e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HLDNKGNC_01783	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HLDNKGNC_01784	2.83e-142	ykoX	-	-	S	-	-	-	membrane-associated protein
HLDNKGNC_01785	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HLDNKGNC_01786	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_01787	2.2e-210	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HLDNKGNC_01788	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HLDNKGNC_01789	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HLDNKGNC_01790	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLDNKGNC_01791	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HLDNKGNC_01793	5.95e-27	ykzE	-	-	-	-	-	-	-
HLDNKGNC_01794	1.07e-240	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HLDNKGNC_01795	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_01796	4.58e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLDNKGNC_01798	1.62e-253	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HLDNKGNC_01799	1.6e-289	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HLDNKGNC_01800	2.83e-193	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLDNKGNC_01801	3.95e-295	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDNKGNC_01802	4.62e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HLDNKGNC_01803	4.17e-174	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HLDNKGNC_01804	1.06e-145	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HLDNKGNC_01805	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HLDNKGNC_01806	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HLDNKGNC_01808	4.81e-94	eag	-	-	-	-	-	-	-
HLDNKGNC_01809	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HLDNKGNC_01810	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HLDNKGNC_01811	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HLDNKGNC_01812	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HLDNKGNC_01813	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLDNKGNC_01814	2.26e-225	ykvI	-	-	S	-	-	-	membrane
HLDNKGNC_01815	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HLDNKGNC_01816	4.03e-104	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HLDNKGNC_01817	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLDNKGNC_01818	4.77e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HLDNKGNC_01819	7.06e-80	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLDNKGNC_01820	7.68e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_01821	2.47e-271	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLDNKGNC_01822	7.56e-48	-	3.5.1.104	-	M	ko:K22278	-	ko00000,ko01000	LysM domain
HLDNKGNC_01823	1.5e-205	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HLDNKGNC_01824	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HLDNKGNC_01825	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01826	2.6e-39	-	-	-	-	-	-	-	-
HLDNKGNC_01827	5.26e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HLDNKGNC_01828	4.55e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_01829	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
HLDNKGNC_01830	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HLDNKGNC_01831	3.99e-09	-	-	-	-	-	-	-	-
HLDNKGNC_01832	1.93e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HLDNKGNC_01833	2.21e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01834	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HLDNKGNC_01835	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_01836	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HLDNKGNC_01837	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLDNKGNC_01838	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01839	2.13e-257	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HLDNKGNC_01840	1.28e-61	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_01841	1.03e-48	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_01842	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_01843	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HLDNKGNC_01844	4.4e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HLDNKGNC_01845	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLDNKGNC_01846	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_01847	3.44e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLDNKGNC_01848	1.05e-22	-	-	-	-	-	-	-	-
HLDNKGNC_01849	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HLDNKGNC_01850	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
HLDNKGNC_01851	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_01852	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01853	4.06e-211	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HLDNKGNC_01854	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_01855	0.0	ybfG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HLDNKGNC_01857	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HLDNKGNC_01858	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01859	2.62e-121	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HLDNKGNC_01860	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HLDNKGNC_01861	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
HLDNKGNC_01862	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_01863	1.05e-111	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
HLDNKGNC_01864	1.49e-223	ykuO	-	-	-	-	-	-	-
HLDNKGNC_01865	1.03e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLDNKGNC_01866	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLDNKGNC_01867	1.33e-274	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLDNKGNC_01868	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HLDNKGNC_01869	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HLDNKGNC_01870	1.14e-128	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HLDNKGNC_01871	1.47e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
HLDNKGNC_01872	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
HLDNKGNC_01873	8.49e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
HLDNKGNC_01874	1.26e-139	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLDNKGNC_01875	1.26e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLDNKGNC_01876	9.69e-310	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HLDNKGNC_01877	3.44e-122	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HLDNKGNC_01878	3.83e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HLDNKGNC_01879	6.92e-45	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HLDNKGNC_01880	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLDNKGNC_01881	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLDNKGNC_01882	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
HLDNKGNC_01883	2.34e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLDNKGNC_01884	8.67e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_01885	2.01e-267	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLDNKGNC_01886	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_01887	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HLDNKGNC_01888	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HLDNKGNC_01889	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLDNKGNC_01890	5.43e-52	ykoA	-	-	-	-	-	-	-
HLDNKGNC_01891	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLDNKGNC_01892	1.59e-212	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLDNKGNC_01893	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HLDNKGNC_01894	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HLDNKGNC_01895	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HLDNKGNC_01896	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HLDNKGNC_01897	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HLDNKGNC_01898	6.91e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HLDNKGNC_01899	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HLDNKGNC_01900	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLDNKGNC_01901	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDNKGNC_01902	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLDNKGNC_01903	1.18e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HLDNKGNC_01904	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLDNKGNC_01905	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HLDNKGNC_01906	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HLDNKGNC_01907	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLDNKGNC_01908	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLDNKGNC_01909	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLDNKGNC_01910	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLDNKGNC_01911	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HLDNKGNC_01912	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HLDNKGNC_01913	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HLDNKGNC_01914	4.34e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HLDNKGNC_01915	4.48e-35	ykzI	-	-	-	-	-	-	-
HLDNKGNC_01916	1.84e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HLDNKGNC_01917	1.73e-99	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HLDNKGNC_01918	1.74e-221	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HLDNKGNC_01919	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HLDNKGNC_01920	0.0	ylaA	-	-	-	-	-	-	-
HLDNKGNC_01921	1.44e-56	ylaB	-	-	-	-	-	-	-
HLDNKGNC_01922	3.56e-115	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_01924	1.62e-55	ylaE	-	-	-	-	-	-	-
HLDNKGNC_01925	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HLDNKGNC_01926	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLDNKGNC_01927	8.88e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
HLDNKGNC_01928	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01929	2.97e-127	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLDNKGNC_01930	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HLDNKGNC_01931	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HLDNKGNC_01932	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLDNKGNC_01933	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HLDNKGNC_01934	7.36e-273	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLDNKGNC_01935	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLDNKGNC_01936	7.82e-210	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HLDNKGNC_01937	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLDNKGNC_01938	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HLDNKGNC_01939	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLDNKGNC_01940	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HLDNKGNC_01941	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HLDNKGNC_01942	1.48e-214	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HLDNKGNC_01943	6.56e-81	ylbA	-	-	S	-	-	-	YugN-like family
HLDNKGNC_01944	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HLDNKGNC_01945	2.09e-254	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HLDNKGNC_01946	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
HLDNKGNC_01947	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HLDNKGNC_01948	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HLDNKGNC_01949	5.1e-51	ylbG	-	-	S	-	-	-	UPF0298 protein
HLDNKGNC_01950	7.09e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HLDNKGNC_01951	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLDNKGNC_01952	1.58e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HLDNKGNC_01953	1.04e-175	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HLDNKGNC_01954	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLDNKGNC_01955	4.29e-294	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLDNKGNC_01957	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HLDNKGNC_01958	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLDNKGNC_01959	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HLDNKGNC_01960	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HLDNKGNC_01961	2.17e-212	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLDNKGNC_01962	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HLDNKGNC_01963	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLDNKGNC_01964	4.76e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLDNKGNC_01965	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HLDNKGNC_01966	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLDNKGNC_01967	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HLDNKGNC_01968	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLDNKGNC_01969	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLDNKGNC_01970	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLDNKGNC_01971	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLDNKGNC_01972	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLDNKGNC_01973	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HLDNKGNC_01974	1.18e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLDNKGNC_01975	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01976	7.27e-124	ylxX	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_01977	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
HLDNKGNC_01978	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLDNKGNC_01979	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLDNKGNC_01980	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HLDNKGNC_01982	4.25e-220	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HLDNKGNC_01983	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_01984	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_01985	1.57e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HLDNKGNC_01986	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HLDNKGNC_01987	1.46e-50	ylmC	-	-	S	-	-	-	sporulation protein
HLDNKGNC_01988	4.36e-202	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HLDNKGNC_01989	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLDNKGNC_01990	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLDNKGNC_01991	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HLDNKGNC_01992	8.64e-178	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HLDNKGNC_01993	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HLDNKGNC_01994	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLDNKGNC_01995	4.55e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HLDNKGNC_01996	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLDNKGNC_01997	3.52e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLDNKGNC_01998	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLDNKGNC_01999	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HLDNKGNC_02000	3.46e-212	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLDNKGNC_02001	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLDNKGNC_02002	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLDNKGNC_02003	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HLDNKGNC_02004	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HLDNKGNC_02005	3e-221	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLDNKGNC_02006	4.43e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLDNKGNC_02007	5.18e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLDNKGNC_02009	4.19e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HLDNKGNC_02010	2.98e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HLDNKGNC_02011	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HLDNKGNC_02012	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HLDNKGNC_02013	5.9e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HLDNKGNC_02014	2.4e-186	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HLDNKGNC_02015	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HLDNKGNC_02016	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HLDNKGNC_02017	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HLDNKGNC_02018	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
HLDNKGNC_02019	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HLDNKGNC_02020	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLDNKGNC_02021	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLDNKGNC_02022	8.5e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLDNKGNC_02023	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLDNKGNC_02024	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLDNKGNC_02025	2.03e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLDNKGNC_02026	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLDNKGNC_02027	8.79e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLDNKGNC_02028	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLDNKGNC_02029	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLDNKGNC_02030	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLDNKGNC_02031	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLDNKGNC_02032	2.24e-154	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLDNKGNC_02033	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLDNKGNC_02034	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02035	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HLDNKGNC_02036	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HLDNKGNC_02037	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HLDNKGNC_02038	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLDNKGNC_02039	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HLDNKGNC_02040	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLDNKGNC_02041	1.31e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLDNKGNC_02042	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HLDNKGNC_02043	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLDNKGNC_02044	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLDNKGNC_02045	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLDNKGNC_02046	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLDNKGNC_02047	1.67e-114	-	-	-	-	-	-	-	-
HLDNKGNC_02048	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLDNKGNC_02049	1.61e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLDNKGNC_02050	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLDNKGNC_02051	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLDNKGNC_02052	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
HLDNKGNC_02053	1.51e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLDNKGNC_02054	9.8e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLDNKGNC_02055	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLDNKGNC_02056	2.32e-199	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLDNKGNC_02057	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLDNKGNC_02058	0.0	ylqG	-	-	-	-	-	-	-
HLDNKGNC_02059	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HLDNKGNC_02060	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HLDNKGNC_02061	1.26e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLDNKGNC_02062	6.01e-214	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HLDNKGNC_02063	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLDNKGNC_02064	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLDNKGNC_02065	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HLDNKGNC_02066	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLDNKGNC_02067	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLDNKGNC_02068	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HLDNKGNC_02069	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HLDNKGNC_02070	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HLDNKGNC_02071	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HLDNKGNC_02072	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HLDNKGNC_02073	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLDNKGNC_02074	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HLDNKGNC_02075	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HLDNKGNC_02076	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HLDNKGNC_02077	5.08e-84	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HLDNKGNC_02078	1e-308	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HLDNKGNC_02079	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HLDNKGNC_02080	1.66e-174	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HLDNKGNC_02081	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HLDNKGNC_02082	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLDNKGNC_02083	2.28e-252	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HLDNKGNC_02084	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HLDNKGNC_02085	1.3e-135	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HLDNKGNC_02086	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HLDNKGNC_02087	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HLDNKGNC_02088	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HLDNKGNC_02089	7.85e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLDNKGNC_02090	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLDNKGNC_02091	5.65e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HLDNKGNC_02092	1.09e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HLDNKGNC_02093	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HLDNKGNC_02094	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HLDNKGNC_02095	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HLDNKGNC_02096	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HLDNKGNC_02097	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HLDNKGNC_02098	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_02099	6.62e-99	ylxL	-	-	-	-	-	-	-
HLDNKGNC_02100	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLDNKGNC_02101	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLDNKGNC_02102	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLDNKGNC_02103	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLDNKGNC_02104	1.57e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLDNKGNC_02105	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLDNKGNC_02106	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HLDNKGNC_02107	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLDNKGNC_02108	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLDNKGNC_02109	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDNKGNC_02110	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLDNKGNC_02111	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLDNKGNC_02112	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HLDNKGNC_02113	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HLDNKGNC_02114	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLDNKGNC_02115	1.58e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HLDNKGNC_02116	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLDNKGNC_02117	5.79e-218	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLDNKGNC_02118	3.84e-231	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLDNKGNC_02119	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLDNKGNC_02120	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLDNKGNC_02121	2.5e-233	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HLDNKGNC_02122	2.3e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HLDNKGNC_02123	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HLDNKGNC_02124	5.3e-208	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HLDNKGNC_02125	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HLDNKGNC_02126	1.66e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLDNKGNC_02127	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLDNKGNC_02128	1.57e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLDNKGNC_02129	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLDNKGNC_02130	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HLDNKGNC_02131	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
HLDNKGNC_02132	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLDNKGNC_02133	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_02134	1.46e-265	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_02135	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
HLDNKGNC_02136	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
HLDNKGNC_02137	5.2e-167	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HLDNKGNC_02138	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HLDNKGNC_02139	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HLDNKGNC_02140	3.05e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HLDNKGNC_02141	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLDNKGNC_02142	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLDNKGNC_02143	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLDNKGNC_02144	2.82e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
HLDNKGNC_02145	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLDNKGNC_02146	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HLDNKGNC_02147	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HLDNKGNC_02148	4.81e-252	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HLDNKGNC_02149	2.4e-277	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLDNKGNC_02150	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLDNKGNC_02151	3.65e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HLDNKGNC_02152	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HLDNKGNC_02153	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLDNKGNC_02154	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLDNKGNC_02157	7.11e-75	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HLDNKGNC_02158	3.77e-61	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH nucleases
HLDNKGNC_02161	3.06e-65	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HLDNKGNC_02162	3.08e-92	-	-	-	L	-	-	-	Phage integrase family
HLDNKGNC_02168	1.13e-24	-	-	-	-	-	-	-	-
HLDNKGNC_02169	1.17e-88	-	-	-	S	-	-	-	Phage terminase, small subunit
HLDNKGNC_02171	5.91e-92	-	-	-	S	-	-	-	Regulatory protein YrvL
HLDNKGNC_02173	1.88e-125	ymcC	-	-	S	-	-	-	Membrane
HLDNKGNC_02174	2.94e-141	pksA	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02175	4.02e-167	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HLDNKGNC_02176	3.08e-207	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLDNKGNC_02178	1.2e-238	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HLDNKGNC_02179	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HLDNKGNC_02180	3.17e-50	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HLDNKGNC_02181	4.36e-303	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLDNKGNC_02182	1.13e-312	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HLDNKGNC_02183	1.01e-183	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HLDNKGNC_02184	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HLDNKGNC_02185	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLDNKGNC_02186	0.0	-	-	-	Q	ko:K13612	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HLDNKGNC_02187	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLDNKGNC_02188	0.0	-	-	-	IQ	ko:K13611,ko:K13613,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HLDNKGNC_02189	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HLDNKGNC_02190	1.44e-296	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLDNKGNC_02191	8.03e-81	ymzB	-	-	-	-	-	-	-
HLDNKGNC_02192	2.67e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLDNKGNC_02193	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HLDNKGNC_02195	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
HLDNKGNC_02196	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HLDNKGNC_02197	2.6e-72	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
HLDNKGNC_02198	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HLDNKGNC_02200	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
HLDNKGNC_02201	9.69e-224	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLDNKGNC_02202	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HLDNKGNC_02203	1.63e-31	-	-	-	-	-	-	-	-
HLDNKGNC_02204	1.2e-30	ymzA	-	-	-	-	-	-	-
HLDNKGNC_02205	2.9e-65	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HLDNKGNC_02206	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDNKGNC_02207	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDNKGNC_02208	2.24e-141	-	-	-	-	-	-	-	-
HLDNKGNC_02209	3.88e-150	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLDNKGNC_02210	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HLDNKGNC_02211	1.05e-292	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLDNKGNC_02212	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HLDNKGNC_02213	2.85e-89	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HLDNKGNC_02214	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLDNKGNC_02215	2.21e-197	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDNKGNC_02216	7.89e-105	-	-	-	S	ko:K03824	-	ko00000,ko01000	family acetyltransferase
HLDNKGNC_02217	9.61e-167	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HLDNKGNC_02218	1.9e-47	-	-	-	-	-	-	-	-
HLDNKGNC_02219	2.23e-86	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HLDNKGNC_02220	1.42e-167	-	-	-	V	-	-	-	HNH endonuclease
HLDNKGNC_02221	0.0	-	-	-	UW	ko:K21487,ko:K21489,ko:K21491,ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HLDNKGNC_02222	1.08e-121	-	-	-	S	ko:K21490	-	ko00000,ko02048	SMI1 / KNR4 family (SUKH-1)
HLDNKGNC_02223	2.18e-132	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HLDNKGNC_02226	9.03e-48	-	-	-	-	-	-	-	-
HLDNKGNC_02228	1.01e-68	-	-	-	S	-	-	-	YolD-like protein
HLDNKGNC_02229	8.38e-297	-	-	-	S	-	-	-	damaged DNA binding
HLDNKGNC_02231	1.21e-244	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLDNKGNC_02232	2.05e-51	-	-	-	S	-	-	-	Bacteriophage holin
HLDNKGNC_02234	2.61e-241	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
HLDNKGNC_02236	0.0	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
HLDNKGNC_02237	9.28e-166	-	-	-	-	-	-	-	-
HLDNKGNC_02238	0.0	-	-	-	S	-	-	-	Pfam Transposase IS66
HLDNKGNC_02239	1.7e-186	-	-	-	S	-	-	-	Phage tail protein
HLDNKGNC_02240	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HLDNKGNC_02241	1.27e-65	-	-	-	-	-	-	-	-
HLDNKGNC_02246	2.26e-243	-	-	-	A	-	-	-	Belongs to the 'phage' integrase family
HLDNKGNC_02247	1.27e-76	-	-	-	-	-	-	-	-
HLDNKGNC_02248	8.36e-73	-	-	-	-	-	-	-	-
HLDNKGNC_02251	8.57e-227	-	-	-	-	-	-	-	-
HLDNKGNC_02252	7.43e-77	-	-	-	-	-	-	-	-
HLDNKGNC_02255	3.71e-144	-	-	-	-	-	-	-	-
HLDNKGNC_02256	2.4e-169	-	-	-	-	-	-	-	-
HLDNKGNC_02257	1.26e-117	-	-	-	-	-	-	-	-
HLDNKGNC_02258	2.24e-155	-	-	-	-	-	-	-	-
HLDNKGNC_02260	1.22e-88	-	-	-	-	-	-	-	-
HLDNKGNC_02261	1.34e-104	-	-	-	-	-	-	-	-
HLDNKGNC_02262	3.43e-236	-	-	-	-	-	-	-	-
HLDNKGNC_02263	2.05e-121	-	-	-	-	-	-	-	-
HLDNKGNC_02264	0.0	-	-	-	-	-	-	-	-
HLDNKGNC_02265	0.0	-	-	-	-	-	-	-	-
HLDNKGNC_02266	0.0	-	-	-	S	-	-	-	Terminase-like family
HLDNKGNC_02267	1.49e-223	-	-	-	-	-	-	-	-
HLDNKGNC_02268	4.47e-44	-	-	-	-	-	-	-	-
HLDNKGNC_02270	7.53e-283	-	-	-	S	-	-	-	hydrolase activity
HLDNKGNC_02273	8.19e-95	-	-	-	-	-	-	-	-
HLDNKGNC_02274	1.12e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLDNKGNC_02275	0.0	-	-	-	-	-	-	-	-
HLDNKGNC_02277	2.08e-45	-	-	-	D	-	-	-	nuclear chromosome segregation
HLDNKGNC_02279	4.62e-293	-	-	-	S	-	-	-	DNA replication origin binding
HLDNKGNC_02289	5.26e-21	-	-	-	-	-	-	-	-
HLDNKGNC_02293	1.56e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HLDNKGNC_02294	4.82e-69	ynaF	-	-	-	-	-	-	-
HLDNKGNC_02296	2.45e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HLDNKGNC_02298	2.35e-95	-	-	-	K	-	-	-	Divergent AAA domain
HLDNKGNC_02304	1.55e-40	-	-	-	-	-	-	-	-
HLDNKGNC_02305	2.2e-125	-	-	-	-	-	-	-	-
HLDNKGNC_02307	5.02e-90	-	-	-	-	-	-	-	-
HLDNKGNC_02314	3.7e-314	-	-	-	-	-	-	-	-
HLDNKGNC_02319	3.49e-106	-	-	-	S	-	-	-	dUTPase
HLDNKGNC_02324	9.87e-87	-	-	-	-	-	-	-	-
HLDNKGNC_02329	5.52e-101	yoqH	-	-	M	-	-	-	LysM domain
HLDNKGNC_02334	1.36e-68	-	-	-	-	-	-	-	-
HLDNKGNC_02336	1.52e-70	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HLDNKGNC_02337	6.43e-96	-	-	-	-	-	-	-	-
HLDNKGNC_02338	1.38e-185	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HLDNKGNC_02339	5.07e-165	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HLDNKGNC_02341	2.94e-204	-	-	-	-	-	-	-	-
HLDNKGNC_02344	2.62e-176	-	-	-	S	-	-	-	Pfam:DUF867
HLDNKGNC_02345	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HLDNKGNC_02350	1.37e-222	-	-	-	-	-	-	-	-
HLDNKGNC_02351	5.88e-208	-	-	-	S	-	-	-	AAA domain
HLDNKGNC_02353	2.52e-304	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HLDNKGNC_02354	1.38e-192	-	-	-	L	-	-	-	DNA primase activity
HLDNKGNC_02355	3.08e-215	-	-	-	S	-	-	-	PD-(D/E)XK nuclease superfamily
HLDNKGNC_02356	0.0	-	-	-	L	-	-	-	DNA polymerase elongation subunit (Family B)
HLDNKGNC_02357	4.58e-28	-	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02360	7.24e-102	tmk	2.1.1.45, 2.7.4.9	-	F	ko:K00560,ko:K00943	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dTDP biosynthetic process
HLDNKGNC_02362	1.05e-12	-	-	-	S	-	-	-	phosphatase activity
HLDNKGNC_02364	2.51e-298	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HLDNKGNC_02379	8.58e-82	-	-	-	S	-	-	-	NrdI Flavodoxin like
HLDNKGNC_02380	1.88e-159	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDNKGNC_02381	2.95e-63	-	-	-	S	-	-	-	HNH endonuclease
HLDNKGNC_02382	4.75e-237	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDNKGNC_02384	9.62e-242	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLDNKGNC_02385	3.21e-49	-	-	-	O	-	-	-	Glutaredoxin
HLDNKGNC_02386	1.37e-93	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HLDNKGNC_02387	1.06e-17	-	-	-	V	-	-	-	COG4767 Glycopeptide antibiotics resistance protein
HLDNKGNC_02390	5.73e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLDNKGNC_02396	3.07e-39	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLDNKGNC_02397	5.11e-204	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLDNKGNC_02407	1.08e-117	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLDNKGNC_02408	2.38e-37	-	-	-	-	-	-	-	-
HLDNKGNC_02409	4.28e-31	-	-	-	-	-	-	-	-
HLDNKGNC_02410	5.86e-54	-	-	-	-	-	-	-	-
HLDNKGNC_02411	1.07e-307	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HLDNKGNC_02413	4.94e-13	-	-	-	-	-	-	-	-
HLDNKGNC_02417	4.03e-302	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HLDNKGNC_02418	1.28e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02419	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HLDNKGNC_02420	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HLDNKGNC_02421	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HLDNKGNC_02422	5.65e-147	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HLDNKGNC_02423	1.02e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HLDNKGNC_02424	6.16e-199	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HLDNKGNC_02425	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_02426	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HLDNKGNC_02427	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HLDNKGNC_02428	2.77e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_02429	1.05e-295	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HLDNKGNC_02430	5.31e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HLDNKGNC_02431	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HLDNKGNC_02432	4.47e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_02433	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HLDNKGNC_02434	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HLDNKGNC_02435	7.68e-275	ywfA	-	-	EGP	-	-	-	-transporter
HLDNKGNC_02436	3.54e-316	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLDNKGNC_02437	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HLDNKGNC_02438	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLDNKGNC_02439	2.11e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HLDNKGNC_02440	3.7e-101	-	-	-	-	-	-	-	-
HLDNKGNC_02441	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HLDNKGNC_02442	1.41e-205	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLDNKGNC_02443	3.7e-233	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLDNKGNC_02444	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLDNKGNC_02445	1.35e-238	spsG	-	-	M	-	-	-	Spore Coat
HLDNKGNC_02446	3.82e-168	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HLDNKGNC_02447	6.52e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HLDNKGNC_02448	1.41e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HLDNKGNC_02449	2.16e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HLDNKGNC_02450	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HLDNKGNC_02451	6.64e-186	spsA	-	-	M	-	-	-	Spore Coat
HLDNKGNC_02452	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HLDNKGNC_02453	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
HLDNKGNC_02454	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
HLDNKGNC_02455	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HLDNKGNC_02456	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLDNKGNC_02457	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLDNKGNC_02458	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HLDNKGNC_02460	1.02e-144	ywdD	-	-	-	-	-	-	-
HLDNKGNC_02461	7.92e-76	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HLDNKGNC_02462	2.21e-187	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLDNKGNC_02463	6.19e-39	ywdA	-	-	-	-	-	-	-
HLDNKGNC_02464	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HLDNKGNC_02465	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02466	1.68e-179	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HLDNKGNC_02467	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLDNKGNC_02469	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLDNKGNC_02470	3.44e-238	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_02471	9.4e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HLDNKGNC_02472	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLDNKGNC_02473	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HLDNKGNC_02474	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HLDNKGNC_02475	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HLDNKGNC_02476	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLDNKGNC_02477	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HLDNKGNC_02478	5.11e-49	ydaS	-	-	S	-	-	-	membrane
HLDNKGNC_02479	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLDNKGNC_02480	1.59e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLDNKGNC_02481	3.88e-76	gtcA	-	-	S	-	-	-	GtrA-like protein
HLDNKGNC_02482	6.9e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
HLDNKGNC_02484	7.41e-65	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HLDNKGNC_02485	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDNKGNC_02486	1.26e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HLDNKGNC_02487	5.13e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HLDNKGNC_02488	5.68e-245	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HLDNKGNC_02489	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HLDNKGNC_02490	1.74e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLDNKGNC_02491	3.79e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLDNKGNC_02492	1.56e-202	ywbI	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02493	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HLDNKGNC_02494	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HLDNKGNC_02495	6.12e-277	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
HLDNKGNC_02496	6.33e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HLDNKGNC_02497	5.68e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HLDNKGNC_02498	1.99e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HLDNKGNC_02499	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HLDNKGNC_02500	2.81e-316	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDNKGNC_02501	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLDNKGNC_02502	1.19e-311	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02503	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLDNKGNC_02504	5.37e-216	gspA	-	-	M	-	-	-	General stress
HLDNKGNC_02505	2.11e-159	ywaF	-	-	S	-	-	-	Integral membrane protein
HLDNKGNC_02506	1.46e-113	ywaE	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02507	3.68e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLDNKGNC_02508	1.57e-314	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HLDNKGNC_02509	2.67e-116	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDNKGNC_02510	1.13e-63	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HLDNKGNC_02511	2.79e-165	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
HLDNKGNC_02512	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HLDNKGNC_02513	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HLDNKGNC_02514	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_02515	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HLDNKGNC_02516	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_02517	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLDNKGNC_02518	8e-176	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02519	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HLDNKGNC_02520	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLDNKGNC_02521	1.58e-50	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02522	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDNKGNC_02523	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HLDNKGNC_02524	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HLDNKGNC_02525	8.94e-28	yxzF	-	-	-	-	-	-	-
HLDNKGNC_02526	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLDNKGNC_02527	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLDNKGNC_02528	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLDNKGNC_02529	3.96e-179	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLDNKGNC_02530	1.16e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_02531	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HLDNKGNC_02532	1.75e-43	-	-	-	-	-	-	-	-
HLDNKGNC_02533	4.05e-64	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
HLDNKGNC_02534	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_02535	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HLDNKGNC_02536	1.03e-199	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLDNKGNC_02537	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HLDNKGNC_02538	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HLDNKGNC_02539	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HLDNKGNC_02540	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HLDNKGNC_02541	3.97e-310	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HLDNKGNC_02542	0.0	-	-	-	O	-	-	-	Peptidase family M48
HLDNKGNC_02544	6.16e-198	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HLDNKGNC_02545	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_02546	3.89e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HLDNKGNC_02547	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLDNKGNC_02548	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLDNKGNC_02549	4.99e-100	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HLDNKGNC_02550	3.5e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLDNKGNC_02551	7.69e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
HLDNKGNC_02552	7.59e-256	-	-	-	T	-	-	-	Signal transduction histidine kinase
HLDNKGNC_02553	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
HLDNKGNC_02554	3.16e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLDNKGNC_02557	8.27e-111	yxjI	-	-	S	-	-	-	LURP-one-related
HLDNKGNC_02558	1.28e-278	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HLDNKGNC_02559	1.09e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HLDNKGNC_02560	3.23e-173	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HLDNKGNC_02561	4.86e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLDNKGNC_02562	6.6e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLDNKGNC_02563	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HLDNKGNC_02564	6.94e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HLDNKGNC_02565	4.23e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLDNKGNC_02566	1.78e-134	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HLDNKGNC_02567	1.88e-62	yxiS	-	-	-	-	-	-	-
HLDNKGNC_02568	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLDNKGNC_02569	4.03e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HLDNKGNC_02570	1.07e-184	bglS	-	-	M	-	-	-	licheninase activity
HLDNKGNC_02571	2.31e-192	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HLDNKGNC_02572	5.09e-141	-	-	-	-	-	-	-	-
HLDNKGNC_02573	7.67e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HLDNKGNC_02574	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HLDNKGNC_02575	3.1e-268	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLDNKGNC_02576	2.01e-69	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HLDNKGNC_02577	1.88e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HLDNKGNC_02579	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HLDNKGNC_02580	4.36e-212	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_02581	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLDNKGNC_02582	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLDNKGNC_02583	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02584	6.08e-59	-	-	-	-	-	-	-	-
HLDNKGNC_02585	1.58e-66	-	-	-	-	-	-	-	-
HLDNKGNC_02586	5.71e-253	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HLDNKGNC_02587	3.27e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
HLDNKGNC_02588	2.39e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HLDNKGNC_02589	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HLDNKGNC_02590	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HLDNKGNC_02591	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HLDNKGNC_02592	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HLDNKGNC_02593	1.51e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HLDNKGNC_02594	1.14e-229	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HLDNKGNC_02595	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLDNKGNC_02596	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HLDNKGNC_02597	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLDNKGNC_02598	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLDNKGNC_02599	4.97e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLDNKGNC_02600	7.18e-195	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
HLDNKGNC_02601	6.07e-253	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
HLDNKGNC_02602	1.02e-314	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HLDNKGNC_02603	2.89e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HLDNKGNC_02604	3.94e-170	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_02605	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLDNKGNC_02606	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HLDNKGNC_02607	1.27e-120	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_02608	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_02609	2.5e-233	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HLDNKGNC_02610	4.68e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HLDNKGNC_02614	7.32e-42	yxeE	-	-	-	-	-	-	-
HLDNKGNC_02615	7.57e-28	yxeD	-	-	-	-	-	-	-
HLDNKGNC_02616	9.65e-91	-	-	-	-	-	-	-	-
HLDNKGNC_02617	4.99e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDNKGNC_02618	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HLDNKGNC_02619	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HLDNKGNC_02620	9.39e-182	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_02621	1.1e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02622	3.98e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_02623	6.95e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HLDNKGNC_02624	8e-194	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HLDNKGNC_02625	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HLDNKGNC_02626	1.55e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HLDNKGNC_02627	8.46e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HLDNKGNC_02628	1.23e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HLDNKGNC_02629	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HLDNKGNC_02630	6.81e-225	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HLDNKGNC_02631	9.49e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HLDNKGNC_02632	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLDNKGNC_02633	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLDNKGNC_02634	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HLDNKGNC_02636	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
HLDNKGNC_02637	5.91e-313	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDNKGNC_02638	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HLDNKGNC_02640	1.19e-192	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_02641	1.71e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLDNKGNC_02642	9.79e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLDNKGNC_02643	6.59e-111	yxbD	3.2.2.20	-	K	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Acetyltransferase (GNAT) domain
HLDNKGNC_02644	1.16e-239	-	-	-	S	-	-	-	A domain family that is part of the cupin metalloenzyme superfamily.
HLDNKGNC_02645	1.83e-175	yxbB	-	-	Q	-	-	-	Met-10+ like-protein
HLDNKGNC_02646	1.49e-58	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HLDNKGNC_02647	8.99e-114	yxnB	-	-	-	-	-	-	-
HLDNKGNC_02648	0.0	-	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLDNKGNC_02649	1.8e-271	yxaM	-	-	U	-	-	-	MFS_1 like family
HLDNKGNC_02650	2.63e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
HLDNKGNC_02651	1.43e-85	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HLDNKGNC_02652	2.83e-99	yxaI	-	-	S	-	-	-	membrane protein domain
HLDNKGNC_02653	5.33e-286	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLDNKGNC_02654	1.05e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
HLDNKGNC_02655	9.61e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HLDNKGNC_02656	3.53e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02657	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_02658	5.1e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HLDNKGNC_02659	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HLDNKGNC_02660	1.47e-244	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HLDNKGNC_02661	6.98e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLDNKGNC_02662	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HLDNKGNC_02663	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLDNKGNC_02664	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HLDNKGNC_02665	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLDNKGNC_02666	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HLDNKGNC_02667	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HLDNKGNC_02668	1.11e-237	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HLDNKGNC_02669	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLDNKGNC_02670	3.29e-12	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02671	7.19e-23	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_02672	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_02673	2.5e-23	-	-	-	-	-	-	-	-
HLDNKGNC_02674	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HLDNKGNC_02675	0.0	-	-	-	L	-	-	-	AAA domain
HLDNKGNC_02676	2.54e-312	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLDNKGNC_02677	4.16e-57	-	-	-	S	-	-	-	MazG-like family
HLDNKGNC_02678	3.24e-59	-	-	-	-	-	-	-	-
HLDNKGNC_02679	4.36e-101	-	-	-	V	-	-	-	Restriction endonuclease
HLDNKGNC_02680	5.23e-18	-	-	-	-	-	-	-	-
HLDNKGNC_02681	2.16e-66	-	-	-	-	-	-	-	-
HLDNKGNC_02682	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLDNKGNC_02684	6.41e-53	-	-	-	-	-	-	-	-
HLDNKGNC_02685	1.81e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLDNKGNC_02687	3.87e-42	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HLDNKGNC_02688	3.84e-260	yycP	-	-	-	-	-	-	-
HLDNKGNC_02689	9.7e-169	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HLDNKGNC_02690	3.69e-111	yycN	-	-	K	-	-	-	Acetyltransferase
HLDNKGNC_02691	1.75e-238	-	-	-	S	-	-	-	aspartate phosphatase
HLDNKGNC_02693	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HLDNKGNC_02694	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLDNKGNC_02695	2.38e-293	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HLDNKGNC_02696	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HLDNKGNC_02697	1.05e-275	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLDNKGNC_02698	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HLDNKGNC_02699	6.94e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02700	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02701	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02702	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_02707	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLDNKGNC_02708	3.29e-99	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_02709	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLDNKGNC_02710	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HLDNKGNC_02712	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
HLDNKGNC_02713	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HLDNKGNC_02714	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLDNKGNC_02715	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HLDNKGNC_02716	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLDNKGNC_02717	5.23e-205	yybS	-	-	S	-	-	-	membrane
HLDNKGNC_02719	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HLDNKGNC_02720	7.81e-89	yybR	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02721	5.7e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HLDNKGNC_02722	3.19e-90	-	-	-	-	-	-	-	-
HLDNKGNC_02724	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_02725	5.1e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HLDNKGNC_02726	9.72e-182	-	-	-	-	-	-	-	-
HLDNKGNC_02727	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
HLDNKGNC_02728	5.67e-162	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HLDNKGNC_02729	2.49e-276	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_02730	1.07e-209	yybE	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02731	7.91e-104	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_02732	1.42e-96	yybC	-	-	-	-	-	-	-
HLDNKGNC_02733	1.46e-162	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLDNKGNC_02734	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
HLDNKGNC_02735	3.46e-94	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_02736	8.63e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HLDNKGNC_02737	2.72e-119	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HLDNKGNC_02738	8.62e-137	yyaP	-	-	H	-	-	-	RibD C-terminal domain
HLDNKGNC_02739	4.54e-316	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_02740	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HLDNKGNC_02741	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLDNKGNC_02742	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HLDNKGNC_02743	1.33e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HLDNKGNC_02744	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_02745	2.79e-226	ccpB	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02746	1.63e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLDNKGNC_02747	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLDNKGNC_02748	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLDNKGNC_02749	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLDNKGNC_02750	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLDNKGNC_02751	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLDNKGNC_02752	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02753	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
HLDNKGNC_02754	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HLDNKGNC_02755	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLDNKGNC_02756	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HLDNKGNC_02757	9.26e-98	-	-	-	S	-	-	-	Bacterial PH domain
HLDNKGNC_02758	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HLDNKGNC_02759	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HLDNKGNC_02760	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLDNKGNC_02761	9.06e-317	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLDNKGNC_02762	8.72e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HLDNKGNC_02763	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLDNKGNC_02764	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLDNKGNC_02765	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLDNKGNC_02766	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLDNKGNC_02767	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HLDNKGNC_02768	9.16e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLDNKGNC_02769	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HLDNKGNC_02770	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDNKGNC_02771	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLDNKGNC_02772	1.77e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HLDNKGNC_02773	1.2e-122	-	-	-	M	-	-	-	FR47-like protein
HLDNKGNC_02774	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HLDNKGNC_02775	1.04e-103	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HLDNKGNC_02776	5.59e-109	yuaE	-	-	S	-	-	-	DinB superfamily
HLDNKGNC_02777	5.8e-137	yuaD	-	-	-	-	-	-	-
HLDNKGNC_02778	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HLDNKGNC_02779	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLDNKGNC_02780	2.39e-121	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HLDNKGNC_02781	5.83e-118	yuaB	-	-	-	-	-	-	-
HLDNKGNC_02782	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HLDNKGNC_02783	3.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
HLDNKGNC_02784	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
HLDNKGNC_02785	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDNKGNC_02786	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HLDNKGNC_02787	1.61e-112	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
HLDNKGNC_02789	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLDNKGNC_02790	8.19e-251	yubA	-	-	S	-	-	-	transporter activity
HLDNKGNC_02791	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLDNKGNC_02792	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HLDNKGNC_02793	4.94e-73	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HLDNKGNC_02794	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HLDNKGNC_02795	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLDNKGNC_02796	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HLDNKGNC_02797	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_02798	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_02799	1.2e-297	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_02800	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_02801	1.02e-179	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HLDNKGNC_02802	5e-48	-	-	-	-	-	-	-	-
HLDNKGNC_02803	1.04e-94	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HLDNKGNC_02804	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLDNKGNC_02805	1.03e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLDNKGNC_02806	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HLDNKGNC_02807	6.2e-48	-	-	-	-	-	-	-	-
HLDNKGNC_02808	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HLDNKGNC_02809	2.06e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HLDNKGNC_02810	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
HLDNKGNC_02812	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLDNKGNC_02813	6.49e-290	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HLDNKGNC_02814	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HLDNKGNC_02815	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HLDNKGNC_02816	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HLDNKGNC_02817	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HLDNKGNC_02818	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02819	4.03e-200	yugF	-	-	I	-	-	-	Hydrolase
HLDNKGNC_02820	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HLDNKGNC_02821	2.34e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HLDNKGNC_02822	3.04e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02823	2.4e-89	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HLDNKGNC_02824	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HLDNKGNC_02826	1.08e-242	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HLDNKGNC_02827	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HLDNKGNC_02828	3.31e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02829	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HLDNKGNC_02830	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLDNKGNC_02831	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HLDNKGNC_02832	6.07e-252	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HLDNKGNC_02833	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_02834	3.03e-235	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLDNKGNC_02835	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLDNKGNC_02836	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HLDNKGNC_02837	1e-21	-	-	-	-	-	-	-	-
HLDNKGNC_02838	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLDNKGNC_02839	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLDNKGNC_02840	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLDNKGNC_02841	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLDNKGNC_02842	2.47e-101	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLDNKGNC_02843	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLDNKGNC_02844	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HLDNKGNC_02845	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HLDNKGNC_02846	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_02847	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02849	1.24e-79	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HLDNKGNC_02850	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
HLDNKGNC_02851	8.73e-09	yuzC	-	-	-	-	-	-	-
HLDNKGNC_02852	1.97e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HLDNKGNC_02853	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLDNKGNC_02854	1.89e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HLDNKGNC_02855	5.17e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLDNKGNC_02856	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
HLDNKGNC_02857	1.44e-42	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HLDNKGNC_02858	2.73e-244	yueF	-	-	S	-	-	-	transporter activity
HLDNKGNC_02859	2.21e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HLDNKGNC_02860	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HLDNKGNC_02861	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HLDNKGNC_02862	2.04e-169	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_02863	5.1e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HLDNKGNC_02864	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HLDNKGNC_02865	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLDNKGNC_02866	4.28e-271	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HLDNKGNC_02867	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HLDNKGNC_02868	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HLDNKGNC_02869	2e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
HLDNKGNC_02870	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HLDNKGNC_02871	3.44e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HLDNKGNC_02872	1.42e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HLDNKGNC_02873	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_02874	1.1e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HLDNKGNC_02875	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HLDNKGNC_02876	4.74e-287	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HLDNKGNC_02877	3.37e-177	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02878	8.94e-213	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HLDNKGNC_02879	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HLDNKGNC_02880	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HLDNKGNC_02881	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HLDNKGNC_02882	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HLDNKGNC_02883	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HLDNKGNC_02884	1.39e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02885	1.14e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
HLDNKGNC_02886	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLDNKGNC_02887	1.92e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HLDNKGNC_02889	4.51e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLDNKGNC_02890	9.91e-150	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
HLDNKGNC_02891	8.04e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_02892	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HLDNKGNC_02893	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLDNKGNC_02894	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLDNKGNC_02895	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HLDNKGNC_02896	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLDNKGNC_02897	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02898	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HLDNKGNC_02899	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HLDNKGNC_02900	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLDNKGNC_02901	5.64e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HLDNKGNC_02902	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HLDNKGNC_02903	2.57e-252	yutH	-	-	S	-	-	-	Spore coat protein
HLDNKGNC_02904	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HLDNKGNC_02905	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLDNKGNC_02906	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HLDNKGNC_02907	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_02908	9.45e-145	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLDNKGNC_02909	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HLDNKGNC_02910	7.63e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HLDNKGNC_02911	2.46e-171	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HLDNKGNC_02912	1.39e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HLDNKGNC_02913	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLDNKGNC_02914	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDNKGNC_02915	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HLDNKGNC_02916	1.07e-79	yunG	-	-	-	-	-	-	-
HLDNKGNC_02917	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HLDNKGNC_02918	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HLDNKGNC_02919	3.99e-296	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
HLDNKGNC_02920	1.65e-285	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HLDNKGNC_02921	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HLDNKGNC_02922	1.41e-79	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HLDNKGNC_02923	8.45e-123	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HLDNKGNC_02924	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HLDNKGNC_02925	1.12e-183	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HLDNKGNC_02926	3.58e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HLDNKGNC_02927	3.46e-241	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HLDNKGNC_02929	6.99e-305	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HLDNKGNC_02930	1.99e-302	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HLDNKGNC_02931	5.37e-217	bsn	-	-	L	-	-	-	Ribonuclease
HLDNKGNC_02932	1.99e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_02933	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HLDNKGNC_02934	2.74e-208	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HLDNKGNC_02935	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HLDNKGNC_02936	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLDNKGNC_02937	2.36e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HLDNKGNC_02938	1.29e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HLDNKGNC_02939	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HLDNKGNC_02940	9.57e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HLDNKGNC_02942	3.35e-56	-	-	-	-	-	-	-	-
HLDNKGNC_02943	9.82e-84	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_02944	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HLDNKGNC_02945	2.55e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HLDNKGNC_02946	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLDNKGNC_02947	7.43e-313	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HLDNKGNC_02948	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HLDNKGNC_02949	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLDNKGNC_02950	5.86e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HLDNKGNC_02951	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HLDNKGNC_02952	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLDNKGNC_02953	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HLDNKGNC_02954	2e-73	yusE	-	-	CO	-	-	-	Thioredoxin
HLDNKGNC_02955	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HLDNKGNC_02956	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HLDNKGNC_02957	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HLDNKGNC_02958	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HLDNKGNC_02959	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HLDNKGNC_02960	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HLDNKGNC_02961	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HLDNKGNC_02962	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
HLDNKGNC_02963	2.09e-212	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HLDNKGNC_02964	2.23e-54	-	-	-	-	-	-	-	-
HLDNKGNC_02965	2.48e-69	yusN	-	-	M	-	-	-	Coat F domain
HLDNKGNC_02966	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HLDNKGNC_02967	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HLDNKGNC_02968	1.7e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HLDNKGNC_02969	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02970	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HLDNKGNC_02971	3.66e-64	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HLDNKGNC_02972	2.51e-195	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLDNKGNC_02973	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
HLDNKGNC_02974	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HLDNKGNC_02975	4.49e-196	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02976	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HLDNKGNC_02977	9.63e-306	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLDNKGNC_02978	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_02979	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02980	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_02981	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLDNKGNC_02982	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HLDNKGNC_02983	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLDNKGNC_02984	2.38e-252	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HLDNKGNC_02985	1.19e-240	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HLDNKGNC_02986	4.46e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_02987	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_02988	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HLDNKGNC_02989	6.28e-176	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLDNKGNC_02990	9.94e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HLDNKGNC_02991	1.51e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HLDNKGNC_02992	1.13e-288	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_02993	1.93e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HLDNKGNC_02994	7.39e-309	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HLDNKGNC_02995	1.28e-234	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_02996	8.54e-218	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HLDNKGNC_02997	2.12e-181	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_02998	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HLDNKGNC_02999	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_03000	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_03001	5.07e-32	-	-	-	-	-	-	-	-
HLDNKGNC_03002	7.02e-128	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HLDNKGNC_03003	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
HLDNKGNC_03004	9.23e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HLDNKGNC_03005	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HLDNKGNC_03006	7.7e-273	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HLDNKGNC_03007	2.69e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03008	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
HLDNKGNC_03009	8.38e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLDNKGNC_03010	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03011	8.53e-237	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03012	3.65e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLDNKGNC_03013	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLDNKGNC_03014	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HLDNKGNC_03015	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HLDNKGNC_03016	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HLDNKGNC_03017	5.98e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HLDNKGNC_03018	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HLDNKGNC_03019	1.74e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HLDNKGNC_03020	3.58e-200	yvgN	-	-	S	-	-	-	reductase
HLDNKGNC_03021	7.97e-113	yvgO	-	-	-	-	-	-	-
HLDNKGNC_03022	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HLDNKGNC_03023	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HLDNKGNC_03024	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HLDNKGNC_03025	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLDNKGNC_03027	2.34e-139	yvgT	-	-	S	-	-	-	membrane
HLDNKGNC_03028	5.7e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HLDNKGNC_03029	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
HLDNKGNC_03030	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HLDNKGNC_03031	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLDNKGNC_03032	3.66e-41	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HLDNKGNC_03033	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HLDNKGNC_03034	4.89e-248	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLDNKGNC_03035	3.59e-154	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLDNKGNC_03036	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HLDNKGNC_03037	2.02e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HLDNKGNC_03038	3.52e-71	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HLDNKGNC_03039	2.35e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLDNKGNC_03040	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_03042	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HLDNKGNC_03043	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLDNKGNC_03044	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HLDNKGNC_03045	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HLDNKGNC_03046	4.91e-195	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
HLDNKGNC_03047	7.45e-49	yvzC	-	-	K	-	-	-	transcriptional
HLDNKGNC_03048	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HLDNKGNC_03049	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLDNKGNC_03050	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
HLDNKGNC_03051	0.0	-	-	-	Q	ko:K15665	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_03052	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_03053	3.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HLDNKGNC_03054	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HLDNKGNC_03055	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HLDNKGNC_03056	6.78e-100	xkdJ	-	-	-	-	-	-	-
HLDNKGNC_03057	3.95e-113	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HLDNKGNC_03058	3.02e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HLDNKGNC_03059	2.32e-82	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HLDNKGNC_03060	1.59e-216	xkdG	-	-	S	-	-	-	Phage capsid family
HLDNKGNC_03061	9.88e-177	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HLDNKGNC_03062	0.0	yqbA	-	-	S	-	-	-	portal protein
HLDNKGNC_03063	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HLDNKGNC_03064	1.87e-176	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HLDNKGNC_03065	9.88e-111	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLDNKGNC_03069	3.55e-151	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HLDNKGNC_03070	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HLDNKGNC_03072	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLDNKGNC_03073	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HLDNKGNC_03074	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HLDNKGNC_03075	2.44e-142	yjqB	-	-	S	-	-	-	Pfam:DUF867
HLDNKGNC_03076	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
HLDNKGNC_03077	3.76e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HLDNKGNC_03078	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
HLDNKGNC_03080	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLDNKGNC_03081	5.59e-310	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HLDNKGNC_03082	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
HLDNKGNC_03083	1.59e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDNKGNC_03084	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HLDNKGNC_03085	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HLDNKGNC_03086	4.02e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HLDNKGNC_03087	1.86e-287	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
HLDNKGNC_03088	6.38e-195	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLDNKGNC_03089	2.27e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HLDNKGNC_03090	1.47e-242	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HLDNKGNC_03091	4.91e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HLDNKGNC_03092	3.56e-313	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HLDNKGNC_03093	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HLDNKGNC_03094	3.56e-279	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLDNKGNC_03095	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLDNKGNC_03096	2.36e-116	yjlB	-	-	S	-	-	-	Cupin domain
HLDNKGNC_03097	8.58e-223	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HLDNKGNC_03098	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLDNKGNC_03099	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HLDNKGNC_03100	8.33e-187	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HLDNKGNC_03101	1.11e-41	-	-	-	-	-	-	-	-
HLDNKGNC_03102	2.5e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLDNKGNC_03103	3.19e-284	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLDNKGNC_03105	1.83e-147	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLDNKGNC_03107	9.24e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HLDNKGNC_03108	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HLDNKGNC_03109	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HLDNKGNC_03110	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HLDNKGNC_03111	8.57e-39	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HLDNKGNC_03112	8.64e-146	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HLDNKGNC_03113	4.62e-29	yjfB	-	-	S	-	-	-	Putative motility protein
HLDNKGNC_03114	1.5e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
HLDNKGNC_03115	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HLDNKGNC_03117	1.52e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLDNKGNC_03118	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HLDNKGNC_03119	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HLDNKGNC_03120	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLDNKGNC_03122	4.38e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLDNKGNC_03123	4.79e-78	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HLDNKGNC_03124	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLDNKGNC_03125	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_03126	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HLDNKGNC_03127	0.000759	-	-	-	-	-	-	-	-
HLDNKGNC_03128	6.61e-179	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_03129	2.57e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HLDNKGNC_03130	6.82e-113	yqaS	-	-	L	-	-	-	DNA packaging
HLDNKGNC_03132	1.51e-104	-	-	-	L	-	-	-	Transposase
HLDNKGNC_03134	1.78e-67	yjcN	-	-	-	-	-	-	-
HLDNKGNC_03135	6.21e-268	-	-	-	S	-	-	-	Putative amidase domain
HLDNKGNC_03139	1.74e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HLDNKGNC_03140	1.68e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HLDNKGNC_03141	7.47e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLDNKGNC_03142	3.28e-272	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLDNKGNC_03143	7.77e-177	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HLDNKGNC_03144	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HLDNKGNC_03145	9.05e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_03146	6.31e-51	-	-	-	-	-	-	-	-
HLDNKGNC_03147	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLDNKGNC_03148	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HLDNKGNC_03151	5.03e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HLDNKGNC_03152	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HLDNKGNC_03153	2.34e-51	cotW	-	-	-	ko:K06341	-	ko00000	-
HLDNKGNC_03154	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HLDNKGNC_03155	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HLDNKGNC_03156	4.76e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HLDNKGNC_03157	1.4e-101	yjbX	-	-	S	-	-	-	Spore coat protein
HLDNKGNC_03158	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HLDNKGNC_03159	1.97e-190	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLDNKGNC_03160	6.18e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLDNKGNC_03161	5.57e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HLDNKGNC_03162	3.63e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HLDNKGNC_03163	5.4e-276	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HLDNKGNC_03164	2.32e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HLDNKGNC_03165	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLDNKGNC_03166	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLDNKGNC_03167	2.71e-179	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HLDNKGNC_03168	5.21e-203	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLDNKGNC_03169	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLDNKGNC_03170	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HLDNKGNC_03171	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HLDNKGNC_03172	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_03173	2.07e-128	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLDNKGNC_03174	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HLDNKGNC_03175	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HLDNKGNC_03176	2.68e-28	-	-	-	-	-	-	-	-
HLDNKGNC_03177	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HLDNKGNC_03178	5.11e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLDNKGNC_03179	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLDNKGNC_03180	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HLDNKGNC_03181	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLDNKGNC_03182	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_03183	3.35e-260	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLDNKGNC_03184	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_03185	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_03186	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_03187	1.03e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_03188	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HLDNKGNC_03189	1.02e-233	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HLDNKGNC_03190	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HLDNKGNC_03191	1.48e-197	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_03192	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLDNKGNC_03193	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HLDNKGNC_03194	3.43e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_03195	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HLDNKGNC_03196	9.1e-191	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HLDNKGNC_03197	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLDNKGNC_03198	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLDNKGNC_03199	2.67e-38	yjzB	-	-	-	-	-	-	-
HLDNKGNC_03200	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HLDNKGNC_03201	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HLDNKGNC_03202	5e-130	yjaV	-	-	-	-	-	-	-
HLDNKGNC_03203	4.88e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HLDNKGNC_03204	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLDNKGNC_03205	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HLDNKGNC_03206	1.43e-223	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLDNKGNC_03207	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HLDNKGNC_03208	2.71e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLDNKGNC_03209	1.09e-274	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HLDNKGNC_03210	7.35e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HLDNKGNC_03211	2.03e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLDNKGNC_03212	1.18e-251	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLDNKGNC_03213	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HLDNKGNC_03214	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HLDNKGNC_03215	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
HLDNKGNC_03216	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HLDNKGNC_03217	2.06e-184	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HLDNKGNC_03218	2.52e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLDNKGNC_03219	1.92e-08	-	-	-	-	-	-	-	-
HLDNKGNC_03220	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HLDNKGNC_03221	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HLDNKGNC_03222	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLDNKGNC_03223	1.3e-201	yitS	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_03224	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HLDNKGNC_03225	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
HLDNKGNC_03226	9.7e-117	-	-	-	-	-	-	-	-
HLDNKGNC_03227	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HLDNKGNC_03228	1.9e-126	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HLDNKGNC_03229	1.17e-217	-	-	-	-	-	-	-	-
HLDNKGNC_03230	4.16e-122	-	-	-	-	-	-	-	-
HLDNKGNC_03231	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HLDNKGNC_03232	6.1e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HLDNKGNC_03233	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLDNKGNC_03234	5.09e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_03235	4.89e-201	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_03236	4.1e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_03237	2.8e-279	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLDNKGNC_03238	6.62e-140	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLDNKGNC_03239	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
HLDNKGNC_03240	1.75e-158	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
HLDNKGNC_03241	3.87e-184	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HLDNKGNC_03242	2.55e-291	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HLDNKGNC_03243	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HLDNKGNC_03244	4.53e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLDNKGNC_03245	1.24e-95	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HLDNKGNC_03246	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03247	2.47e-136	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HLDNKGNC_03248	5.98e-121	yisT	-	-	S	-	-	-	DinB family
HLDNKGNC_03249	2.02e-246	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HLDNKGNC_03250	2.91e-232	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HLDNKGNC_03251	4.04e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03252	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
HLDNKGNC_03253	3.24e-191	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HLDNKGNC_03254	1.07e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
HLDNKGNC_03255	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLDNKGNC_03256	1.5e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HLDNKGNC_03257	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLDNKGNC_03258	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
HLDNKGNC_03259	7.64e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HLDNKGNC_03260	2.11e-219	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HLDNKGNC_03261	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HLDNKGNC_03262	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HLDNKGNC_03263	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HLDNKGNC_03264	6.73e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HLDNKGNC_03265	7.36e-34	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HLDNKGNC_03266	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HLDNKGNC_03267	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HLDNKGNC_03268	5.27e-64	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HLDNKGNC_03269	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HLDNKGNC_03270	9.84e-281	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLDNKGNC_03271	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLDNKGNC_03272	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HLDNKGNC_03273	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
HLDNKGNC_03274	2.05e-76	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
HLDNKGNC_03275	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HLDNKGNC_03276	1.93e-267	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HLDNKGNC_03277	1.02e-258	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HLDNKGNC_03278	4.36e-239	yhjM	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03279	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HLDNKGNC_03280	2.63e-205	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLDNKGNC_03281	3.27e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HLDNKGNC_03282	8.57e-271	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HLDNKGNC_03283	3.29e-121	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_03284	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HLDNKGNC_03285	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLDNKGNC_03286	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_03287	6.86e-77	yhjD	-	-	-	-	-	-	-
HLDNKGNC_03288	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HLDNKGNC_03289	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDNKGNC_03290	1.18e-55	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HLDNKGNC_03291	1.21e-214	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_03292	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HLDNKGNC_03293	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
HLDNKGNC_03294	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_03295	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HLDNKGNC_03296	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HLDNKGNC_03297	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLDNKGNC_03298	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HLDNKGNC_03299	2.46e-249	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLDNKGNC_03300	3.93e-140	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HLDNKGNC_03301	3.77e-221	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HLDNKGNC_03302	3.98e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HLDNKGNC_03303	5.12e-101	-	-	-	K	-	-	-	acetyltransferase
HLDNKGNC_03304	1.7e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HLDNKGNC_03305	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
HLDNKGNC_03306	2.78e-85	yhfM	-	-	-	-	-	-	-
HLDNKGNC_03307	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HLDNKGNC_03308	1.23e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
HLDNKGNC_03309	6.47e-242	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HLDNKGNC_03310	3.43e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HLDNKGNC_03311	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLDNKGNC_03312	4.38e-93	-	-	-	S	-	-	-	ASCH
HLDNKGNC_03313	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
HLDNKGNC_03314	1.61e-178	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HLDNKGNC_03315	7.21e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLDNKGNC_03316	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HLDNKGNC_03317	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03318	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HLDNKGNC_03319	3.82e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HLDNKGNC_03320	7.46e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HLDNKGNC_03321	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLDNKGNC_03322	2.65e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HLDNKGNC_03323	5.79e-44	-	-	-	C	-	-	-	Rubrerythrin
HLDNKGNC_03324	1.15e-313	yhfA	-	-	C	-	-	-	membrane
HLDNKGNC_03325	3.11e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HLDNKGNC_03326	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
HLDNKGNC_03327	1.48e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLDNKGNC_03328	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HLDNKGNC_03329	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HLDNKGNC_03330	2.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLDNKGNC_03331	5.2e-103	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HLDNKGNC_03332	9.66e-30	-	-	-	-	-	-	-	-
HLDNKGNC_03333	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HLDNKGNC_03334	2.01e-147	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HLDNKGNC_03335	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HLDNKGNC_03336	1.4e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HLDNKGNC_03337	6.57e-179	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLDNKGNC_03338	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HLDNKGNC_03339	7.42e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HLDNKGNC_03340	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLDNKGNC_03341	1.5e-297	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HLDNKGNC_03342	2.97e-271	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HLDNKGNC_03343	2.27e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03344	9.36e-36	-	-	-	S	-	-	-	YhzD-like protein
HLDNKGNC_03345	2.06e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HLDNKGNC_03347	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HLDNKGNC_03348	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HLDNKGNC_03349	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HLDNKGNC_03350	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLDNKGNC_03351	5.9e-258	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HLDNKGNC_03352	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLDNKGNC_03353	6.89e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HLDNKGNC_03354	3.37e-276	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HLDNKGNC_03355	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HLDNKGNC_03356	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HLDNKGNC_03357	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HLDNKGNC_03358	1.84e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HLDNKGNC_03359	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLDNKGNC_03360	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HLDNKGNC_03361	1.1e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLDNKGNC_03362	2.83e-300	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HLDNKGNC_03363	1.06e-195	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HLDNKGNC_03364	5.47e-198	nodB1	-	-	G	-	-	-	deacetylase
HLDNKGNC_03365	1.19e-179	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HLDNKGNC_03366	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HLDNKGNC_03367	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HLDNKGNC_03368	3.68e-172	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HLDNKGNC_03369	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDNKGNC_03370	2.69e-70	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLDNKGNC_03371	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLDNKGNC_03372	2.95e-283	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HLDNKGNC_03373	1.42e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HLDNKGNC_03374	2.54e-303	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HLDNKGNC_03375	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLDNKGNC_03376	3.9e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
HLDNKGNC_03377	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_03378	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HLDNKGNC_03379	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HLDNKGNC_03380	7.13e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLDNKGNC_03381	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03382	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLDNKGNC_03383	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HLDNKGNC_03384	4.52e-203	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_03385	3.72e-261	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HLDNKGNC_03386	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03387	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLDNKGNC_03388	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HLDNKGNC_03389	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HLDNKGNC_03390	8.32e-304	ygxB	-	-	M	-	-	-	Conserved TM helix
HLDNKGNC_03391	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HLDNKGNC_03392	1.4e-269	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HLDNKGNC_03393	1.25e-72	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HLDNKGNC_03394	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HLDNKGNC_03395	5.68e-117	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HLDNKGNC_03396	2.22e-143	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_03397	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_03398	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HLDNKGNC_03399	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HLDNKGNC_03400	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLDNKGNC_03401	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLDNKGNC_03402	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HLDNKGNC_03403	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLDNKGNC_03404	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLDNKGNC_03405	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HLDNKGNC_03406	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HLDNKGNC_03407	2.47e-88	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HLDNKGNC_03408	6.51e-216	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLDNKGNC_03409	7.54e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HLDNKGNC_03410	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLDNKGNC_03411	9.74e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
HLDNKGNC_03412	8e-227	yhcP	-	-	-	-	-	-	-
HLDNKGNC_03413	2.69e-111	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLDNKGNC_03414	2.32e-65	yhcM	-	-	-	-	-	-	-
HLDNKGNC_03415	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLDNKGNC_03416	1.37e-248	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HLDNKGNC_03417	7.14e-191	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLDNKGNC_03418	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HLDNKGNC_03419	1.15e-210	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLDNKGNC_03420	6.47e-213	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03421	3.38e-158	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03422	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03423	2.92e-69	-	-	-	-	-	-	-	-
HLDNKGNC_03424	3.95e-59	yhcC	-	-	-	-	-	-	-
HLDNKGNC_03425	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HLDNKGNC_03426	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HLDNKGNC_03427	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HLDNKGNC_03428	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HLDNKGNC_03429	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HLDNKGNC_03430	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HLDNKGNC_03431	4.06e-103	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HLDNKGNC_03432	4.62e-96	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HLDNKGNC_03433	9.75e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HLDNKGNC_03434	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLDNKGNC_03435	2.77e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
HLDNKGNC_03436	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLDNKGNC_03437	2.73e-147	yhzB	-	-	S	-	-	-	B3/4 domain
HLDNKGNC_03439	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03440	2.79e-102	ygaO	-	-	-	-	-	-	-
HLDNKGNC_03441	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLDNKGNC_03443	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HLDNKGNC_03444	2.39e-189	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLDNKGNC_03445	4.19e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HLDNKGNC_03446	1.36e-192	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HLDNKGNC_03447	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HLDNKGNC_03449	0.0	ygaK	-	-	C	-	-	-	Berberine and berberine like
HLDNKGNC_03450	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HLDNKGNC_03451	3.86e-170	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HLDNKGNC_03452	1.58e-36	-	-	-	-	-	-	-	-
HLDNKGNC_03453	2.22e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
HLDNKGNC_03472	4.02e-201	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HLDNKGNC_03473	7.9e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HLDNKGNC_03474	2.52e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLDNKGNC_03475	5.37e-218	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HLDNKGNC_03476	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HLDNKGNC_03477	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLDNKGNC_03478	3.23e-305	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLDNKGNC_03479	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_03480	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_03481	6.3e-255	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HLDNKGNC_03482	2.22e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HLDNKGNC_03483	1.39e-233	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLDNKGNC_03484	6.55e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLDNKGNC_03486	1.12e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HLDNKGNC_03487	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HLDNKGNC_03488	4.11e-161	-	-	-	-	-	-	-	-
HLDNKGNC_03489	5.33e-287	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLDNKGNC_03490	2.98e-308	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HLDNKGNC_03491	1.24e-156	ydhC	-	-	K	-	-	-	FCD
HLDNKGNC_03492	7.2e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLDNKGNC_03493	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HLDNKGNC_03494	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HLDNKGNC_03495	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
HLDNKGNC_03496	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HLDNKGNC_03497	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_03498	3.44e-117	-	-	-	S	-	-	-	DinB family
HLDNKGNC_03499	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_03500	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HLDNKGNC_03501	3.98e-111	yycN	-	-	K	-	-	-	Acetyltransferase
HLDNKGNC_03502	1.93e-68	-	-	-	S	-	-	-	DoxX-like family
HLDNKGNC_03503	6.42e-123	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLDNKGNC_03504	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLDNKGNC_03505	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLDNKGNC_03506	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLDNKGNC_03507	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLDNKGNC_03508	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLDNKGNC_03510	5.33e-39	-	-	-	-	-	-	-	-
HLDNKGNC_03511	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HLDNKGNC_03512	9.63e-77	ydfQ	-	-	CO	-	-	-	Thioredoxin
HLDNKGNC_03513	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HLDNKGNC_03514	1.11e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HLDNKGNC_03515	8.12e-144	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HLDNKGNC_03516	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLDNKGNC_03517	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HLDNKGNC_03518	2.27e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HLDNKGNC_03519	5.4e-223	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLDNKGNC_03520	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HLDNKGNC_03521	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_03522	7.92e-251	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_03524	1.31e-102	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLDNKGNC_03525	7.14e-157	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLDNKGNC_03526	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HLDNKGNC_03527	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03528	5.77e-196	-	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_03529	3.15e-188	-	-	-	J	-	-	-	GNAT acetyltransferase
HLDNKGNC_03530	1.18e-292	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLDNKGNC_03531	2.11e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HLDNKGNC_03532	2.16e-135	ydeS	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03533	2.84e-250	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HLDNKGNC_03534	6.98e-142	ywrO	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
HLDNKGNC_03535	5.03e-91	ydeP	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03536	1.68e-196	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLDNKGNC_03537	7.42e-75	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLDNKGNC_03538	8.06e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HLDNKGNC_03539	3.03e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HLDNKGNC_03540	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03541	3.67e-194	ydeK	-	-	EG	-	-	-	-transporter
HLDNKGNC_03542	4.22e-111	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HLDNKGNC_03543	4.69e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HLDNKGNC_03544	1.69e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_03545	2.56e-142	-	-	-	-	-	-	-	-
HLDNKGNC_03546	5.52e-133	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HLDNKGNC_03547	9.2e-70	ydeH	-	-	-	-	-	-	-
HLDNKGNC_03548	1.27e-275	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HLDNKGNC_03549	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03550	7.02e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HLDNKGNC_03551	4.39e-218	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLDNKGNC_03552	4.22e-211	-	-	-	K	-	-	-	AraC-like ligand binding domain
HLDNKGNC_03553	2.92e-183	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLDNKGNC_03554	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HLDNKGNC_03555	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HLDNKGNC_03556	4.24e-146	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
HLDNKGNC_03560	3.47e-52	-	-	-	-	-	-	-	-
HLDNKGNC_03561	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HLDNKGNC_03563	1.33e-189	-	-	-	S	-	-	-	Serine aminopeptidase, S33
HLDNKGNC_03565	1.12e-63	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLDNKGNC_03573	1.59e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLDNKGNC_03574	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HLDNKGNC_03575	7.57e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HLDNKGNC_03576	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLDNKGNC_03577	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HLDNKGNC_03578	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HLDNKGNC_03579	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HLDNKGNC_03580	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HLDNKGNC_03581	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HLDNKGNC_03582	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HLDNKGNC_03583	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HLDNKGNC_03584	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HLDNKGNC_03585	1.77e-282	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLDNKGNC_03586	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HLDNKGNC_03587	1.32e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLDNKGNC_03588	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HLDNKGNC_03589	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HLDNKGNC_03590	6.08e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HLDNKGNC_03591	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLDNKGNC_03592	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLDNKGNC_03593	1.46e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLDNKGNC_03594	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
HLDNKGNC_03595	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLDNKGNC_03597	1.14e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
HLDNKGNC_03598	4.82e-276	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HLDNKGNC_03599	9.32e-70	ydbL	-	-	-	-	-	-	-
HLDNKGNC_03600	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLDNKGNC_03601	2.97e-215	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03603	3.25e-231	ydbI	-	-	S	-	-	-	AI-2E family transporter
HLDNKGNC_03604	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLDNKGNC_03605	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HLDNKGNC_03606	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HLDNKGNC_03607	1.23e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HLDNKGNC_03608	1.84e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HLDNKGNC_03609	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HLDNKGNC_03610	7.58e-79	ydbB	-	-	G	-	-	-	Cupin domain
HLDNKGNC_03611	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HLDNKGNC_03612	2.91e-188	ydbA	-	-	P	-	-	-	EcsC protein family
HLDNKGNC_03613	1.85e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HLDNKGNC_03614	1.67e-42	ydaS	-	-	S	-	-	-	membrane
HLDNKGNC_03615	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLDNKGNC_03616	6.14e-53	-	-	-	-	-	-	-	-
HLDNKGNC_03617	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HLDNKGNC_03618	1.58e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HLDNKGNC_03619	0.0	ydaO	-	-	E	-	-	-	amino acid
HLDNKGNC_03620	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HLDNKGNC_03621	1.12e-303	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HLDNKGNC_03622	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HLDNKGNC_03623	1.23e-190	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HLDNKGNC_03624	5.97e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLDNKGNC_03625	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLDNKGNC_03626	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HLDNKGNC_03627	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HLDNKGNC_03628	2.65e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HLDNKGNC_03629	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
HLDNKGNC_03630	3.14e-132	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLDNKGNC_03631	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HLDNKGNC_03632	1.07e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_03633	1.43e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
HLDNKGNC_03634	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HLDNKGNC_03635	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HLDNKGNC_03636	3.5e-219	ycsN	-	-	S	-	-	-	Oxidoreductase
HLDNKGNC_03637	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HLDNKGNC_03638	7.67e-66	yczJ	-	-	S	-	-	-	biosynthesis
HLDNKGNC_03640	4.18e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HLDNKGNC_03641	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03642	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HLDNKGNC_03643	4.84e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HLDNKGNC_03644	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HLDNKGNC_03645	2.78e-273	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HLDNKGNC_03646	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HLDNKGNC_03647	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HLDNKGNC_03649	1.89e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HLDNKGNC_03650	4.68e-140	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
HLDNKGNC_03651	1.78e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLDNKGNC_03652	1.13e-253	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HLDNKGNC_03653	1.08e-268	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HLDNKGNC_03654	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HLDNKGNC_03655	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HLDNKGNC_03656	4.67e-75	-	-	-	-	-	-	-	-
HLDNKGNC_03657	8.26e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLDNKGNC_03658	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HLDNKGNC_03659	7.73e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_03660	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLDNKGNC_03661	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HLDNKGNC_03662	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLDNKGNC_03663	1.14e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLDNKGNC_03664	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLDNKGNC_03665	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLDNKGNC_03666	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
HLDNKGNC_03667	2.9e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HLDNKGNC_03668	1.76e-199	ycnC	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03669	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HLDNKGNC_03670	7.91e-220	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HLDNKGNC_03671	1.33e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03672	4.69e-211	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03673	2.2e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03674	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLDNKGNC_03675	6.5e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HLDNKGNC_03677	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLDNKGNC_03678	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HLDNKGNC_03679	2.23e-165	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_03680	6.39e-275	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HLDNKGNC_03681	4.82e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLDNKGNC_03682	4.63e-254	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HLDNKGNC_03683	8.35e-297	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HLDNKGNC_03684	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HLDNKGNC_03686	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HLDNKGNC_03687	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HLDNKGNC_03688	4.52e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HLDNKGNC_03689	5.69e-105	yclD	-	-	-	-	-	-	-
HLDNKGNC_03690	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HLDNKGNC_03691	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HLDNKGNC_03692	4.34e-138	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLDNKGNC_03693	5.32e-209	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HLDNKGNC_03694	3.03e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLDNKGNC_03695	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLDNKGNC_03696	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HLDNKGNC_03697	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HLDNKGNC_03698	1.17e-145	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HLDNKGNC_03699	9.36e-317	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HLDNKGNC_03700	8.58e-201	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_03701	5.17e-123	-	-	-	S	-	-	-	YcxB-like protein
HLDNKGNC_03702	2.55e-287	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLDNKGNC_03703	6.65e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HLDNKGNC_03704	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HLDNKGNC_03705	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_03706	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_03707	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
HLDNKGNC_03708	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HLDNKGNC_03709	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HLDNKGNC_03710	6.16e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_03711	1.13e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HLDNKGNC_03712	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HLDNKGNC_03713	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HLDNKGNC_03714	1.91e-153	-	-	-	S	-	-	-	AAA domain
HLDNKGNC_03715	9e-32	-	-	-	-	-	-	-	-
HLDNKGNC_03716	1.29e-58	-	-	-	K	-	-	-	MarR family
HLDNKGNC_03717	1.01e-68	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HLDNKGNC_03718	2.43e-100	yckC	-	-	S	-	-	-	membrane
HLDNKGNC_03720	1.78e-185	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HLDNKGNC_03721	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HLDNKGNC_03722	2.08e-285	yciC	-	-	S	-	-	-	GTPases (G3E family)
HLDNKGNC_03723	4.96e-139	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLDNKGNC_03724	1.22e-221	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
HLDNKGNC_03725	1.51e-280	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HLDNKGNC_03727	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HLDNKGNC_03728	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLDNKGNC_03729	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HLDNKGNC_03730	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HLDNKGNC_03731	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HLDNKGNC_03732	1.58e-240	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLDNKGNC_03733	6.2e-205	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HLDNKGNC_03734	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HLDNKGNC_03735	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HLDNKGNC_03736	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HLDNKGNC_03737	2.64e-316	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLDNKGNC_03738	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLDNKGNC_03739	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HLDNKGNC_03740	2.6e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HLDNKGNC_03741	3.16e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HLDNKGNC_03742	3.97e-228	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
HLDNKGNC_03743	8.73e-185	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HLDNKGNC_03744	3.01e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLDNKGNC_03746	7.28e-138	tmrB	-	-	S	-	-	-	AAA domain
HLDNKGNC_03747	5.24e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLDNKGNC_03748	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HLDNKGNC_03749	0.0	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_03750	5.95e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HLDNKGNC_03751	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HLDNKGNC_03752	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_03753	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HLDNKGNC_03754	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLDNKGNC_03755	1.69e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLDNKGNC_03756	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HLDNKGNC_03757	6.39e-104	ycgB	-	-	-	-	-	-	-
HLDNKGNC_03758	0.0	ycgA	-	-	S	-	-	-	Membrane
HLDNKGNC_03759	6.31e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HLDNKGNC_03760	5.76e-210	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HLDNKGNC_03761	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HLDNKGNC_03762	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HLDNKGNC_03763	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HLDNKGNC_03764	6.45e-265	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HLDNKGNC_03765	2.7e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HLDNKGNC_03766	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HLDNKGNC_03767	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HLDNKGNC_03768	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HLDNKGNC_03769	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HLDNKGNC_03770	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HLDNKGNC_03771	3.08e-140	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HLDNKGNC_03772	1.2e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_03773	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLDNKGNC_03774	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLDNKGNC_03775	9.24e-220	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLDNKGNC_03776	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLDNKGNC_03777	1.61e-178	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HLDNKGNC_03778	1.16e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HLDNKGNC_03779	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLDNKGNC_03780	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_03781	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_03782	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HLDNKGNC_03783	9.67e-222	yccK	-	-	C	-	-	-	Aldo keto reductase
HLDNKGNC_03784	1.8e-253	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HLDNKGNC_03785	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLDNKGNC_03786	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HLDNKGNC_03787	3.2e-215	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HLDNKGNC_03788	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HLDNKGNC_03789	1.14e-73	-	-	-	S	-	-	-	RDD family
HLDNKGNC_03790	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLDNKGNC_03791	8.37e-258	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HLDNKGNC_03792	1.88e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HLDNKGNC_03793	2.51e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HLDNKGNC_03794	8.41e-260	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HLDNKGNC_03795	3.43e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLDNKGNC_03796	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLDNKGNC_03797	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLDNKGNC_03798	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HLDNKGNC_03799	3.53e-170	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
HLDNKGNC_03800	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HLDNKGNC_03801	7.41e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HLDNKGNC_03802	5.78e-148	-	-	-	S	-	-	-	ABC-2 family transporter protein
HLDNKGNC_03803	2.36e-216	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_03804	4.56e-216	ycbM	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_03805	3.18e-161	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_03806	3.07e-214	eamA1	-	-	EG	-	-	-	spore germination
HLDNKGNC_03807	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HLDNKGNC_03808	1.05e-223	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HLDNKGNC_03809	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HLDNKGNC_03810	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HLDNKGNC_03811	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HLDNKGNC_03812	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_03813	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLDNKGNC_03814	3.37e-221	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HLDNKGNC_03815	1.72e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HLDNKGNC_03816	2.05e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_03817	3.06e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLDNKGNC_03818	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HLDNKGNC_03820	1.19e-229	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HLDNKGNC_03821	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLDNKGNC_03822	1.99e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HLDNKGNC_03824	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HLDNKGNC_03825	4.29e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLDNKGNC_03826	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_03827	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLDNKGNC_03828	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HLDNKGNC_03829	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03830	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HLDNKGNC_03831	1.58e-59	ybfN	-	-	-	-	-	-	-
HLDNKGNC_03832	1.76e-189	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HLDNKGNC_03833	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HLDNKGNC_03834	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLDNKGNC_03835	3.91e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLDNKGNC_03837	9.75e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HLDNKGNC_03838	3.78e-270	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLDNKGNC_03839	1.23e-186	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HLDNKGNC_03840	2.92e-205	ybfH	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_03841	1.92e-208	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_03842	1.22e-217	ybfA	-	-	K	-	-	-	FR47-like protein
HLDNKGNC_03843	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HLDNKGNC_03844	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HLDNKGNC_03845	4.05e-210	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HLDNKGNC_03846	0.0	ybeC	-	-	E	-	-	-	amino acid
HLDNKGNC_03847	1.11e-54	ybyB	-	-	-	-	-	-	-
HLDNKGNC_03848	2.2e-313	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HLDNKGNC_03849	3.56e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HLDNKGNC_03850	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HLDNKGNC_03851	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HLDNKGNC_03852	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_03853	1.33e-275	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HLDNKGNC_03854	1.56e-194	ybdN	-	-	-	-	-	-	-
HLDNKGNC_03855	2.49e-181	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HLDNKGNC_03857	4.61e-218	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
HLDNKGNC_03858	6.9e-158	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HLDNKGNC_03859	2.13e-228	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLDNKGNC_03860	9.6e-73	-	-	-	-	-	-	-	-
HLDNKGNC_03861	1.09e-256	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HLDNKGNC_03862	9.45e-67	-	-	-	K	-	-	-	Helix-turn-helix domain
HLDNKGNC_03863	1.03e-79	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HLDNKGNC_03864	2.67e-62	-	-	-	-	-	-	-	-
HLDNKGNC_03865	3.43e-123	ybcF	-	-	P	-	-	-	carbonic anhydrase
HLDNKGNC_03866	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
HLDNKGNC_03867	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLDNKGNC_03868	1.06e-128	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLDNKGNC_03869	1.99e-151	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HLDNKGNC_03870	3.79e-220	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLDNKGNC_03871	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLDNKGNC_03872	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLDNKGNC_03873	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_03874	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLDNKGNC_03875	2.63e-150	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HLDNKGNC_03876	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HLDNKGNC_03882	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HLDNKGNC_03883	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
HLDNKGNC_03884	7.81e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLDNKGNC_03885	5.21e-192	ybbH	-	-	K	-	-	-	transcriptional
HLDNKGNC_03886	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HLDNKGNC_03887	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HLDNKGNC_03888	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HLDNKGNC_03889	8.14e-303	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_03890	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HLDNKGNC_03891	1.99e-213	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HLDNKGNC_03892	2.88e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03893	3.51e-228	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLDNKGNC_03894	5.46e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HLDNKGNC_03895	2.34e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
HLDNKGNC_03897	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HLDNKGNC_03898	6.91e-08	-	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HLDNKGNC_03899	7.57e-225	-	-	-	L	-	-	-	Replication protein
HLDNKGNC_03900	1.58e-131	-	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLDNKGNC_03906	1.74e-07	-	-	-	L	-	-	-	COG3843 Type IV secretory pathway, VirD2 components (relaxase)
HLDNKGNC_03908	2.2e-55	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HLDNKGNC_03909	2.26e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLDNKGNC_03910	4.78e-220	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLDNKGNC_03911	2.57e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLDNKGNC_03912	3.49e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLDNKGNC_03913	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HLDNKGNC_03914	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLDNKGNC_03915	6.08e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLDNKGNC_03916	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HLDNKGNC_03917	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLDNKGNC_03918	1.74e-130	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HLDNKGNC_03919	7.95e-135	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HLDNKGNC_03920	1.03e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
HLDNKGNC_03921	1.13e-156	yvbI	-	-	M	-	-	-	Membrane
HLDNKGNC_03922	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HLDNKGNC_03923	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
HLDNKGNC_03924	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLDNKGNC_03925	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HLDNKGNC_03926	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLDNKGNC_03927	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLDNKGNC_03928	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLDNKGNC_03929	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLDNKGNC_03930	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDNKGNC_03931	1.24e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HLDNKGNC_03932	1.04e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLDNKGNC_03933	4.9e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03934	2.27e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HLDNKGNC_03935	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HLDNKGNC_03936	1.17e-246	-	-	-	S	-	-	-	Glycosyl hydrolase
HLDNKGNC_03937	1.69e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLDNKGNC_03938	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HLDNKGNC_03939	9.08e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLDNKGNC_03940	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_03941	6.02e-249	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLDNKGNC_03942	8.31e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HLDNKGNC_03943	1.57e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HLDNKGNC_03944	1.46e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
HLDNKGNC_03945	4.85e-262	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HLDNKGNC_03946	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HLDNKGNC_03947	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HLDNKGNC_03948	1.1e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HLDNKGNC_03949	2.15e-300	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HLDNKGNC_03950	3.4e-294	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HLDNKGNC_03951	6.42e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLDNKGNC_03952	6.85e-146	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HLDNKGNC_03953	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HLDNKGNC_03954	1.36e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HLDNKGNC_03955	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
HLDNKGNC_03956	7.24e-239	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HLDNKGNC_03957	6.67e-282	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HLDNKGNC_03958	1.76e-78	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HLDNKGNC_03959	1.65e-141	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLDNKGNC_03960	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_03961	3.21e-244	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_03962	5.47e-259	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HLDNKGNC_03963	7.05e-248	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HLDNKGNC_03964	3.59e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HLDNKGNC_03965	1.14e-274	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLDNKGNC_03966	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HLDNKGNC_03967	2.32e-283	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HLDNKGNC_03968	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HLDNKGNC_03969	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HLDNKGNC_03970	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HLDNKGNC_03971	3.57e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HLDNKGNC_03972	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HLDNKGNC_03974	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HLDNKGNC_03975	1.5e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HLDNKGNC_03976	6.88e-160	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLDNKGNC_03977	2.32e-68	pbpE	-	-	V	-	-	-	Beta-lactamase
HLDNKGNC_03978	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HLDNKGNC_03979	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HLDNKGNC_03980	0.0	ybeC	-	-	E	-	-	-	amino acid
HLDNKGNC_03981	1.94e-136	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_03982	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HLDNKGNC_03983	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HLDNKGNC_03984	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HLDNKGNC_03985	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HLDNKGNC_03986	9.45e-234	-	-	-	S	-	-	-	Patatin-like phospholipase
HLDNKGNC_03987	3.08e-95	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HLDNKGNC_03988	6.03e-113	sdpB	-	-	S	-	-	-	Vitamin K-dependent gamma-carboxylase
HLDNKGNC_03989	3.45e-47	-	-	-	-	-	-	-	-
HLDNKGNC_03993	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLDNKGNC_03994	1.12e-148	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HLDNKGNC_03995	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HLDNKGNC_03996	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HLDNKGNC_03997	2.56e-193	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HLDNKGNC_03998	6.56e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HLDNKGNC_03999	2.48e-310	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HLDNKGNC_04000	4.19e-302	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HLDNKGNC_04001	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HLDNKGNC_04002	1.27e-220	yvdE	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04003	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLDNKGNC_04004	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HLDNKGNC_04005	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HLDNKGNC_04006	5.7e-132	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HLDNKGNC_04007	1.15e-234	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLDNKGNC_04008	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HLDNKGNC_04009	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLDNKGNC_04010	3.24e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HLDNKGNC_04011	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLDNKGNC_04012	1.37e-45	-	-	-	-	-	-	-	-
HLDNKGNC_04013	3.4e-184	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HLDNKGNC_04014	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HLDNKGNC_04015	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLDNKGNC_04016	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLDNKGNC_04017	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLDNKGNC_04018	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLDNKGNC_04019	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLDNKGNC_04020	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HLDNKGNC_04021	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HLDNKGNC_04022	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLDNKGNC_04024	0.0	-	-	-	-	-	-	-	-
HLDNKGNC_04025	3.02e-170	-	-	-	-	-	-	-	-
HLDNKGNC_04026	3.05e-145	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HLDNKGNC_04027	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLDNKGNC_04028	6.55e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLDNKGNC_04029	1.2e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLDNKGNC_04030	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HLDNKGNC_04031	7.71e-294	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLDNKGNC_04032	3.04e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLDNKGNC_04033	4e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLDNKGNC_04034	3.54e-178	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HLDNKGNC_04035	1.1e-153	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
HLDNKGNC_04036	3.58e-119	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HLDNKGNC_04037	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HLDNKGNC_04038	3.72e-211	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HLDNKGNC_04039	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLDNKGNC_04040	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLDNKGNC_04041	5.07e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLDNKGNC_04042	5.82e-164	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLDNKGNC_04043	3.02e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HLDNKGNC_04044	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HLDNKGNC_04045	7.73e-109	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_04046	2.56e-290	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HLDNKGNC_04047	7.15e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HLDNKGNC_04048	6.2e-114	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLDNKGNC_04049	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLDNKGNC_04050	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HLDNKGNC_04051	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HLDNKGNC_04052	2.36e-220	yvlB	-	-	S	-	-	-	Putative adhesin
HLDNKGNC_04053	4.68e-64	yvlA	-	-	-	-	-	-	-
HLDNKGNC_04054	2.25e-45	yvkN	-	-	-	-	-	-	-
HLDNKGNC_04055	1.75e-146	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLDNKGNC_04056	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLDNKGNC_04057	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLDNKGNC_04058	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_04059	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HLDNKGNC_04060	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04061	2.13e-295	yvkA	-	-	P	-	-	-	-transporter
HLDNKGNC_04062	6.4e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLDNKGNC_04063	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HLDNKGNC_04064	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HLDNKGNC_04065	1.1e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HLDNKGNC_04066	1.5e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HLDNKGNC_04067	3.23e-75	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HLDNKGNC_04068	6.5e-185	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HLDNKGNC_04069	2e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLDNKGNC_04070	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLDNKGNC_04071	1.43e-131	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLDNKGNC_04072	9.14e-88	-	-	-	-	-	-	-	-
HLDNKGNC_04073	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HLDNKGNC_04074	5.15e-91	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HLDNKGNC_04075	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HLDNKGNC_04076	1.56e-76	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HLDNKGNC_04077	1.01e-106	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLDNKGNC_04078	5.02e-39	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HLDNKGNC_04079	5e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HLDNKGNC_04080	6.92e-92	yviE	-	-	-	-	-	-	-
HLDNKGNC_04081	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HLDNKGNC_04082	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HLDNKGNC_04083	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
HLDNKGNC_04084	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HLDNKGNC_04085	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
HLDNKGNC_04086	1.53e-160	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HLDNKGNC_04087	1.04e-60	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HLDNKGNC_04088	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLDNKGNC_04089	7.19e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_04090	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLDNKGNC_04091	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HLDNKGNC_04092	2.41e-155	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HLDNKGNC_04093	3.81e-223	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04094	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HLDNKGNC_04095	1.76e-298	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HLDNKGNC_04096	8.42e-187	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HLDNKGNC_04097	1.36e-145	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HLDNKGNC_04098	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HLDNKGNC_04099	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLDNKGNC_04100	3.42e-280	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HLDNKGNC_04101	3.44e-316	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLDNKGNC_04102	1.49e-143	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLDNKGNC_04103	2.51e-108	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLDNKGNC_04104	6.43e-265	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HLDNKGNC_04105	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HLDNKGNC_04106	9.07e-16	-	-	-	-	-	-	-	-
HLDNKGNC_04107	1.35e-210	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HLDNKGNC_04108	8.63e-274	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLDNKGNC_04109	1.48e-103	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLDNKGNC_04110	6.85e-118	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLDNKGNC_04112	2.74e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLDNKGNC_04113	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLDNKGNC_04114	1.37e-167	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HLDNKGNC_04115	0.0	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLDNKGNC_04116	2.19e-305	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLDNKGNC_04117	1.2e-170	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLDNKGNC_04118	2.29e-74	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HLDNKGNC_04119	3.93e-110	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLDNKGNC_04120	5.44e-117	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLDNKGNC_04121	1.46e-134	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HLDNKGNC_04122	2.82e-186	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HLDNKGNC_04123	4.73e-110	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	M	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLDNKGNC_04124	1.42e-235	tarL	2.7.8.14, 2.7.8.47	-	M	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLDNKGNC_04125	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLDNKGNC_04126	4.72e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLDNKGNC_04127	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HLDNKGNC_04128	1.19e-254	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HLDNKGNC_04129	6.3e-273	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HLDNKGNC_04130	1.84e-314	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLDNKGNC_04131	8.57e-222	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04132	5.95e-204	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLDNKGNC_04133	4.73e-306	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLDNKGNC_04134	2.29e-29	ywtC	-	-	-	-	-	-	-
HLDNKGNC_04135	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HLDNKGNC_04136	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HLDNKGNC_04137	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HLDNKGNC_04138	9.35e-228	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HLDNKGNC_04139	1.45e-203	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLDNKGNC_04140	5.39e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLDNKGNC_04141	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HLDNKGNC_04142	1.36e-202	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLDNKGNC_04143	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HLDNKGNC_04144	6.59e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HLDNKGNC_04145	1.53e-62	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
HLDNKGNC_04146	3.57e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HLDNKGNC_04147	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HLDNKGNC_04148	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLDNKGNC_04149	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
HLDNKGNC_04150	1.13e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLDNKGNC_04151	3.04e-162	ywrJ	-	-	-	-	-	-	-
HLDNKGNC_04152	9.22e-269	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HLDNKGNC_04153	2.17e-16	-	-	-	-	-	-	-	-
HLDNKGNC_04154	1.77e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLDNKGNC_04155	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
HLDNKGNC_04156	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HLDNKGNC_04157	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HLDNKGNC_04158	4.53e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HLDNKGNC_04159	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HLDNKGNC_04161	5.23e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HLDNKGNC_04162	6.44e-207	-	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04163	2.44e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HLDNKGNC_04164	2.78e-127	-	-	-	-	-	-	-	-
HLDNKGNC_04165	1.44e-82	-	-	-	-	-	-	-	-
HLDNKGNC_04166	3.6e-310	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HLDNKGNC_04167	4.26e-51	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HLDNKGNC_04169	4.02e-194	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HLDNKGNC_04170	1.9e-312	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLDNKGNC_04171	2.91e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HLDNKGNC_04172	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HLDNKGNC_04173	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HLDNKGNC_04174	3.6e-25	-	-	-	-	-	-	-	-
HLDNKGNC_04175	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HLDNKGNC_04176	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLDNKGNC_04177	3.06e-201	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HLDNKGNC_04178	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HLDNKGNC_04179	7.02e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HLDNKGNC_04180	3.04e-87	ywpG	-	-	-	-	-	-	-
HLDNKGNC_04181	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
HLDNKGNC_04182	1.55e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HLDNKGNC_04183	4.46e-184	ywpD	-	-	T	-	-	-	Histidine kinase
HLDNKGNC_04184	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLDNKGNC_04185	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLDNKGNC_04186	3.02e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HLDNKGNC_04187	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HLDNKGNC_04188	8.4e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HLDNKGNC_04189	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HLDNKGNC_04190	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HLDNKGNC_04191	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
HLDNKGNC_04192	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HLDNKGNC_04193	2.4e-311	ywoF	-	-	P	-	-	-	Right handed beta helix region
HLDNKGNC_04194	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HLDNKGNC_04195	1.54e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HLDNKGNC_04196	1.48e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
HLDNKGNC_04197	5.89e-100	-	-	-	-	-	-	-	-
HLDNKGNC_04198	2.27e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HLDNKGNC_04199	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HLDNKGNC_04200	7.03e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HLDNKGNC_04201	1.34e-94	ywnJ	-	-	S	-	-	-	VanZ like family
HLDNKGNC_04202	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HLDNKGNC_04203	4.99e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HLDNKGNC_04204	2.22e-16	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HLDNKGNC_04205	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HLDNKGNC_04206	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDNKGNC_04207	1.14e-182	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HLDNKGNC_04208	5.05e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HLDNKGNC_04209	4.32e-147	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLDNKGNC_04210	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04211	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HLDNKGNC_04212	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HLDNKGNC_04213	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HLDNKGNC_04215	1.84e-20	csbD	-	-	K	-	-	-	CsbD-like
HLDNKGNC_04216	1.21e-109	ywmF	-	-	S	-	-	-	Peptidase M50
HLDNKGNC_04217	1.25e-128	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HLDNKGNC_04218	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLDNKGNC_04219	2.22e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HLDNKGNC_04221	1.44e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLDNKGNC_04222	1.56e-156	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HLDNKGNC_04223	9.77e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HLDNKGNC_04224	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLDNKGNC_04225	8.01e-173	ywmB	-	-	S	-	-	-	TATA-box binding
HLDNKGNC_04226	4.54e-45	ywzB	-	-	S	-	-	-	membrane
HLDNKGNC_04227	7.16e-114	ywmA	-	-	-	-	-	-	-
HLDNKGNC_04228	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLDNKGNC_04229	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLDNKGNC_04230	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLDNKGNC_04231	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLDNKGNC_04232	9.66e-117	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDNKGNC_04233	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLDNKGNC_04234	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLDNKGNC_04235	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLDNKGNC_04236	2.23e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HLDNKGNC_04237	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLDNKGNC_04238	1.78e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLDNKGNC_04239	2.9e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HLDNKGNC_04240	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HLDNKGNC_04241	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLDNKGNC_04242	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HLDNKGNC_04243	2.46e-249	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLDNKGNC_04244	1.79e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HLDNKGNC_04245	9.35e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HLDNKGNC_04246	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HLDNKGNC_04248	1.4e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLDNKGNC_04249	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLDNKGNC_04250	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLDNKGNC_04251	6.01e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HLDNKGNC_04252	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLDNKGNC_04253	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HLDNKGNC_04254	8.53e-136	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLDNKGNC_04255	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HLDNKGNC_04256	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLDNKGNC_04257	3.51e-225	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HLDNKGNC_04258	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLDNKGNC_04259	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLDNKGNC_04260	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HLDNKGNC_04261	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HLDNKGNC_04262	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HLDNKGNC_04263	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLDNKGNC_04264	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLDNKGNC_04265	2.98e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
HLDNKGNC_04266	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HLDNKGNC_04267	8.56e-290	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HLDNKGNC_04268	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HLDNKGNC_04269	1.32e-57	ywjC	-	-	-	-	-	-	-
HLDNKGNC_04270	7.5e-122	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HLDNKGNC_04271	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLDNKGNC_04272	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLDNKGNC_04273	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HLDNKGNC_04274	4.59e-121	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HLDNKGNC_04275	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HLDNKGNC_04276	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLDNKGNC_04277	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HLDNKGNC_04278	2.93e-176	ywiC	-	-	S	-	-	-	YwiC-like protein
HLDNKGNC_04279	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HLDNKGNC_04280	4.81e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HLDNKGNC_04281	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLDNKGNC_04282	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HLDNKGNC_04283	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
HLDNKGNC_04284	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HLDNKGNC_04286	1.5e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLDNKGNC_04287	6.61e-295	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HLDNKGNC_04288	4.67e-274	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
HLDNKGNC_04289	1.89e-314	-	-	-	L	-	-	-	Peptidase, M16
HLDNKGNC_04291	9.08e-317	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HLDNKGNC_04292	9.47e-275	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HLDNKGNC_04293	1.64e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HLDNKGNC_04295	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HLDNKGNC_04296	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HLDNKGNC_04297	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLDNKGNC_04298	7.83e-123	ywhD	-	-	S	-	-	-	YwhD family
HLDNKGNC_04299	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
HLDNKGNC_04300	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HLDNKGNC_04301	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04302	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLDNKGNC_04303	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HLDNKGNC_04304	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLDNKGNC_04305	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLDNKGNC_04306	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLDNKGNC_04307	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLDNKGNC_04308	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLDNKGNC_04309	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HLDNKGNC_04310	5.18e-276	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HLDNKGNC_04311	6.7e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HLDNKGNC_04312	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HLDNKGNC_04314	3.98e-295	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLDNKGNC_04315	6.75e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLDNKGNC_04316	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLDNKGNC_04317	2.16e-315	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLDNKGNC_04318	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLDNKGNC_04319	2.6e-233	yaaC	-	-	S	-	-	-	YaaC-like Protein
HLDNKGNC_04320	4.82e-160	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
HLDNKGNC_04323	2.7e-26	-	-	-	-	-	-	-	-
HLDNKGNC_04324	9.42e-103	-	-	-	S	-	-	-	SprT-like family
HLDNKGNC_04326	2.91e-51	nucH	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	Staphylococcal nuclease homologues
HLDNKGNC_04332	6.82e-147	-	-	-	S	-	-	-	SMART Tetratricopeptide domain protein
HLDNKGNC_04340	1.07e-179	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
HLDNKGNC_04341	1.53e-91	-	-	-	-	-	-	-	-
HLDNKGNC_04342	3.33e-266	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HLDNKGNC_04343	1.04e-52	-	-	-	-	-	-	-	-
HLDNKGNC_04344	0.0	-	-	-	S	-	-	-	AAA-like domain
HLDNKGNC_04345	6.04e-83	-	-	-	D	-	-	-	TcpE family
HLDNKGNC_04346	4.51e-37	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLDNKGNC_04347	1.83e-136	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
HLDNKGNC_04348	4.07e-55	-	-	-	-	-	-	-	-
HLDNKGNC_04349	1.09e-181	-	-	-	S	-	-	-	Replication-relaxation
HLDNKGNC_04351	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HLDNKGNC_04353	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLDNKGNC_04355	3.08e-135	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HLDNKGNC_04357	3.21e-95	-	-	-	K	-	-	-	Transcriptional regulator
HLDNKGNC_04358	3.37e-92	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HLDNKGNC_04360	3.62e-199	-	-	-	L	-	-	-	Replication protein
HLDNKGNC_04361	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group