ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NNAPIBNL_00001 6.31e-98 yjhE - - S - - - Phage tail protein
NNAPIBNL_00002 2.97e-95 - - - K - - - Integron-associated effector binding protein
NNAPIBNL_00003 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
NNAPIBNL_00004 1.26e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_00005 9.59e-234 mrjp - - G - - - Major royal jelly protein
NNAPIBNL_00006 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NNAPIBNL_00007 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NNAPIBNL_00008 3.07e-120 - - - E - - - Ring-cleavage extradiol dioxygenase
NNAPIBNL_00009 1.49e-85 yxaI - - S - - - membrane protein domain
NNAPIBNL_00010 1.16e-250 - - - EGP - - - Major Facilitator Superfamily
NNAPIBNL_00011 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNAPIBNL_00012 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
NNAPIBNL_00013 2.12e-185 yxaL - - S - - - PQQ-like domain
NNAPIBNL_00014 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNAPIBNL_00015 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NNAPIBNL_00016 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NNAPIBNL_00017 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_00018 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNAPIBNL_00019 1.56e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNAPIBNL_00020 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NNAPIBNL_00021 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNAPIBNL_00022 1.72e-215 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NNAPIBNL_00023 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNAPIBNL_00024 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNAPIBNL_00025 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NNAPIBNL_00026 1e-224 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NNAPIBNL_00027 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NNAPIBNL_00028 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NNAPIBNL_00029 6.5e-288 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NNAPIBNL_00030 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NNAPIBNL_00031 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NNAPIBNL_00032 6.65e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NNAPIBNL_00033 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NNAPIBNL_00034 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_00035 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_00036 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00037 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNAPIBNL_00038 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
NNAPIBNL_00039 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NNAPIBNL_00040 4.86e-47 - - - - - - - -
NNAPIBNL_00041 9.67e-33 yxeD - - - - - - -
NNAPIBNL_00043 9.45e-26 yxeE - - - - - - -
NNAPIBNL_00046 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
NNAPIBNL_00047 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNAPIBNL_00048 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NNAPIBNL_00049 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNAPIBNL_00050 7.43e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NNAPIBNL_00051 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNAPIBNL_00052 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NNAPIBNL_00053 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NNAPIBNL_00054 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NNAPIBNL_00055 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NNAPIBNL_00056 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NNAPIBNL_00057 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NNAPIBNL_00058 2.49e-244 - - - S - - - AIPR protein
NNAPIBNL_00059 1.12e-99 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
NNAPIBNL_00060 1.46e-12 - - - L - - - Z1 domain
NNAPIBNL_00061 7.34e-294 - - - L - - - Z1 domain
NNAPIBNL_00062 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NNAPIBNL_00063 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NNAPIBNL_00064 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NNAPIBNL_00065 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_00066 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNAPIBNL_00067 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NNAPIBNL_00068 7.42e-202 yxxF - - EG - - - EamA-like transporter family
NNAPIBNL_00069 4.8e-251 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NNAPIBNL_00071 9.79e-75 yxxG - - - - - - -
NNAPIBNL_00072 2.91e-85 yxiG - - - - - - -
NNAPIBNL_00073 4.23e-103 - - - - - - - -
NNAPIBNL_00074 2.79e-140 - - - - - - - -
NNAPIBNL_00076 9.75e-27 - - - - - - - -
NNAPIBNL_00078 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NNAPIBNL_00079 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NNAPIBNL_00080 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NNAPIBNL_00081 9.73e-176 bglS - - M - - - licheninase activity
NNAPIBNL_00082 2.74e-227 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NNAPIBNL_00083 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNAPIBNL_00084 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
NNAPIBNL_00085 3.23e-60 yxiS - - - - - - -
NNAPIBNL_00086 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
NNAPIBNL_00087 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNAPIBNL_00088 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NNAPIBNL_00089 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NNAPIBNL_00090 3.81e-105 yxjI - - S - - - LURP-one-related
NNAPIBNL_00093 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NNAPIBNL_00094 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NNAPIBNL_00095 5.75e-115 yxkC - - S - - - Domain of unknown function (DUF4352)
NNAPIBNL_00097 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NNAPIBNL_00098 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NNAPIBNL_00099 3.56e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_00100 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
NNAPIBNL_00101 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
NNAPIBNL_00102 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NNAPIBNL_00103 2.07e-237 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NNAPIBNL_00106 0.0 - - - KLT - - - Protein kinase domain
NNAPIBNL_00107 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NNAPIBNL_00108 3.05e-93 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
NNAPIBNL_00109 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNAPIBNL_00110 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NNAPIBNL_00111 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NNAPIBNL_00113 3.36e-87 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NNAPIBNL_00114 7.52e-57 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NNAPIBNL_00115 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NNAPIBNL_00116 7.99e-37 yfjT - - - - - - -
NNAPIBNL_00117 9.38e-279 yfkA - - S - - - YfkB-like domain
NNAPIBNL_00118 5.34e-182 yfkC - - M - - - Mechanosensitive ion channel
NNAPIBNL_00119 4.99e-180 yfkD - - S - - - YfkD-like protein
NNAPIBNL_00120 3.14e-234 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NNAPIBNL_00121 1.55e-273 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_00122 8.85e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NNAPIBNL_00123 2.71e-63 yfkI - - S - - - gas vesicle protein
NNAPIBNL_00124 1.38e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNAPIBNL_00125 7.02e-40 yfkK - - S - - - Belongs to the UPF0435 family
NNAPIBNL_00126 1.23e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_00127 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NNAPIBNL_00128 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNAPIBNL_00129 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNAPIBNL_00130 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NNAPIBNL_00131 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NNAPIBNL_00132 5.49e-235 yibE - - S - - - YibE/F-like protein
NNAPIBNL_00133 1.06e-160 yibF - - S - - - YibE/F-like protein
NNAPIBNL_00134 1.34e-154 frp - - C - - - nitroreductase
NNAPIBNL_00135 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NNAPIBNL_00136 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNAPIBNL_00137 3.65e-240 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_00138 1.51e-43 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_00139 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
NNAPIBNL_00140 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
NNAPIBNL_00141 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNAPIBNL_00142 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NNAPIBNL_00143 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NNAPIBNL_00144 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NNAPIBNL_00145 9.77e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NNAPIBNL_00146 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NNAPIBNL_00147 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
NNAPIBNL_00148 5.69e-26 yflI - - - - - - -
NNAPIBNL_00149 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
NNAPIBNL_00150 7.68e-150 yflK - - S - - - protein conserved in bacteria
NNAPIBNL_00151 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NNAPIBNL_00152 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NNAPIBNL_00153 5.2e-113 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNAPIBNL_00154 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NNAPIBNL_00155 1.36e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NNAPIBNL_00156 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NNAPIBNL_00157 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNAPIBNL_00158 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NNAPIBNL_00159 0.0 - - - M - - - cell wall anchor domain
NNAPIBNL_00160 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
NNAPIBNL_00161 0.0 ywpD - - T - - - Histidine kinase
NNAPIBNL_00162 2.85e-92 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
NNAPIBNL_00171 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNAPIBNL_00172 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NNAPIBNL_00173 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNAPIBNL_00174 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNAPIBNL_00175 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNAPIBNL_00176 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NNAPIBNL_00177 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NNAPIBNL_00178 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NNAPIBNL_00179 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNAPIBNL_00180 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NNAPIBNL_00181 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NNAPIBNL_00182 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NNAPIBNL_00183 2.03e-67 yerC - - S - - - protein conserved in bacteria
NNAPIBNL_00184 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NNAPIBNL_00185 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NNAPIBNL_00186 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
NNAPIBNL_00187 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NNAPIBNL_00188 4.48e-81 - - - K - - - helix_turn_helix ASNC type
NNAPIBNL_00189 2.12e-293 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NNAPIBNL_00190 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NNAPIBNL_00191 1.16e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNAPIBNL_00192 2.08e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NNAPIBNL_00193 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNAPIBNL_00194 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNAPIBNL_00195 4.32e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNAPIBNL_00196 2.57e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNAPIBNL_00197 3.8e-163 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NNAPIBNL_00198 4.29e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNAPIBNL_00199 1.15e-280 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNAPIBNL_00200 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNAPIBNL_00201 1.88e-39 yebG - - S - - - NETI protein
NNAPIBNL_00202 1.08e-119 yebE - - S - - - UPF0316 protein
NNAPIBNL_00204 6.92e-165 yebC - - M - - - Membrane
NNAPIBNL_00205 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NNAPIBNL_00206 0.0 - - - S - - - Domain of unknown function (DUF4179)
NNAPIBNL_00207 1.44e-116 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_00208 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NNAPIBNL_00209 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NNAPIBNL_00210 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NNAPIBNL_00211 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NNAPIBNL_00212 7.59e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNAPIBNL_00213 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_00214 1.03e-233 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NNAPIBNL_00215 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NNAPIBNL_00216 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NNAPIBNL_00217 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NNAPIBNL_00218 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NNAPIBNL_00219 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NNAPIBNL_00220 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NNAPIBNL_00221 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
NNAPIBNL_00222 6.58e-27 - - - - - - - -
NNAPIBNL_00223 1.74e-53 - - - L - - - AAA domain
NNAPIBNL_00224 1.63e-281 - - - L - - - AAA domain
NNAPIBNL_00225 0.0 - - - L - - - AAA ATPase domain
NNAPIBNL_00226 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNAPIBNL_00230 5.96e-264 yycP - - - - - - -
NNAPIBNL_00231 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NNAPIBNL_00232 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NNAPIBNL_00233 2.13e-106 yycN - - K - - - Acetyltransferase
NNAPIBNL_00235 2.05e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NNAPIBNL_00236 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NNAPIBNL_00237 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNAPIBNL_00238 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NNAPIBNL_00239 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NNAPIBNL_00240 3.82e-57 sdpR - - K - - - transcriptional
NNAPIBNL_00241 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NNAPIBNL_00242 8.24e-255 - - - S - - - Major Facilitator Superfamily
NNAPIBNL_00243 4.44e-309 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNAPIBNL_00244 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
NNAPIBNL_00245 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
NNAPIBNL_00246 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNAPIBNL_00247 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NNAPIBNL_00248 6.34e-191 yycI - - S - - - protein conserved in bacteria
NNAPIBNL_00249 0.0 yycH - - S - - - protein conserved in bacteria
NNAPIBNL_00250 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_00251 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_00256 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNAPIBNL_00257 1.06e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_00258 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NNAPIBNL_00259 5.03e-35 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NNAPIBNL_00261 1.21e-23 yycC - - K - - - YycC-like protein
NNAPIBNL_00262 3.86e-271 - - - M - - - Glycosyltransferase Family 4
NNAPIBNL_00263 4.55e-243 - - - S - - - Ecdysteroid kinase
NNAPIBNL_00264 2.87e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
NNAPIBNL_00265 3.93e-279 - - - M - - - Glycosyltransferase Family 4
NNAPIBNL_00266 1.44e-150 - - - S - - - GlcNAc-PI de-N-acetylase
NNAPIBNL_00267 4.29e-103 - - - KLT - - - COG0515 Serine threonine protein kinase
NNAPIBNL_00268 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NNAPIBNL_00269 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NNAPIBNL_00270 8.64e-189 yybS - - S - - - membrane
NNAPIBNL_00272 3.93e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
NNAPIBNL_00273 1.79e-84 yybR - - K - - - Transcriptional regulator
NNAPIBNL_00274 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NNAPIBNL_00275 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNAPIBNL_00276 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NNAPIBNL_00277 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NNAPIBNL_00278 7.61e-142 - - - K - - - FCD domain
NNAPIBNL_00279 3.74e-115 - - - S - - - PFAM DinB family protein
NNAPIBNL_00280 1.96e-184 - - - G - - - Major Facilitator Superfamily
NNAPIBNL_00281 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NNAPIBNL_00282 1.56e-144 ydgI - - C - - - nitroreductase
NNAPIBNL_00283 2.55e-85 - - - K - - - Winged helix DNA-binding domain
NNAPIBNL_00284 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_00285 7.24e-97 yybA - - K - - - transcriptional
NNAPIBNL_00286 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
NNAPIBNL_00287 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNAPIBNL_00288 8.63e-130 - - - S - - - Alpha/beta hydrolase family
NNAPIBNL_00289 3.34e-36 - - - - - - - -
NNAPIBNL_00290 1.25e-88 ynaF - - - - - - -
NNAPIBNL_00291 7.1e-207 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NNAPIBNL_00292 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NNAPIBNL_00293 4.75e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNAPIBNL_00294 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NNAPIBNL_00295 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_00296 1.16e-117 ccpB - - K - - - Transcriptional regulator
NNAPIBNL_00297 6.26e-78 ccpB - - K - - - Transcriptional regulator
NNAPIBNL_00298 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NNAPIBNL_00299 2.68e-111 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNAPIBNL_00300 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NNAPIBNL_00301 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNAPIBNL_00302 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNAPIBNL_00303 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NNAPIBNL_00304 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNAPIBNL_00305 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNAPIBNL_00306 1.82e-45 yyzM - - S - - - protein conserved in bacteria
NNAPIBNL_00307 3.84e-215 yyaD - - S - - - Membrane
NNAPIBNL_00308 2.63e-74 yhhY - - K - - - FR47-like protein
NNAPIBNL_00309 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
NNAPIBNL_00310 2.76e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NNAPIBNL_00311 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NNAPIBNL_00312 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NNAPIBNL_00313 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NNAPIBNL_00314 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNAPIBNL_00315 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNAPIBNL_00316 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NNAPIBNL_00317 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNAPIBNL_00318 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNAPIBNL_00319 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNAPIBNL_00320 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNAPIBNL_00321 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NNAPIBNL_00322 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNAPIBNL_00323 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
NNAPIBNL_00324 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNAPIBNL_00325 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNAPIBNL_00347 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NNAPIBNL_00348 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
NNAPIBNL_00349 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NNAPIBNL_00350 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NNAPIBNL_00351 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NNAPIBNL_00352 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNAPIBNL_00353 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNAPIBNL_00354 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNAPIBNL_00355 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NNAPIBNL_00356 9.63e-230 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NNAPIBNL_00357 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NNAPIBNL_00358 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NNAPIBNL_00359 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NNAPIBNL_00360 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NNAPIBNL_00361 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNAPIBNL_00362 9.99e-98 ytkA - - S - - - YtkA-like
NNAPIBNL_00364 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NNAPIBNL_00365 1.67e-77 ytkC - - S - - - Bacteriophage holin family
NNAPIBNL_00366 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NNAPIBNL_00367 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NNAPIBNL_00368 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNAPIBNL_00369 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NNAPIBNL_00370 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NNAPIBNL_00371 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
NNAPIBNL_00372 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NNAPIBNL_00373 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNAPIBNL_00374 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNAPIBNL_00375 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_00376 7.46e-80 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NNAPIBNL_00377 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NNAPIBNL_00378 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NNAPIBNL_00380 4.07e-133 ytqB - - J - - - Putative rRNA methylase
NNAPIBNL_00381 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NNAPIBNL_00382 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
NNAPIBNL_00384 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NNAPIBNL_00385 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00386 1.38e-170 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNAPIBNL_00387 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNAPIBNL_00388 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NNAPIBNL_00389 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00390 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NNAPIBNL_00391 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_00392 4.31e-206 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NNAPIBNL_00393 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00394 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NNAPIBNL_00395 4.62e-130 ywaF - - S - - - Integral membrane protein
NNAPIBNL_00396 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
NNAPIBNL_00397 1.79e-172 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NNAPIBNL_00398 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
NNAPIBNL_00399 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NNAPIBNL_00400 8.6e-69 ytwF - - P - - - Sulfurtransferase
NNAPIBNL_00401 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
NNAPIBNL_00402 2.49e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NNAPIBNL_00403 1.22e-62 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNAPIBNL_00404 4.22e-293 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NNAPIBNL_00405 8.05e-196 yitS - - S - - - protein conserved in bacteria
NNAPIBNL_00406 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_00407 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
NNAPIBNL_00408 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
NNAPIBNL_00409 1.49e-11 - - - - - - - -
NNAPIBNL_00410 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NNAPIBNL_00411 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNAPIBNL_00412 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NNAPIBNL_00413 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NNAPIBNL_00414 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NNAPIBNL_00415 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
NNAPIBNL_00416 1.26e-246 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NNAPIBNL_00417 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NNAPIBNL_00418 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NNAPIBNL_00419 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NNAPIBNL_00420 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNAPIBNL_00421 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NNAPIBNL_00422 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NNAPIBNL_00423 2.07e-38 yjzC - - S - - - YjzC-like protein
NNAPIBNL_00424 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
NNAPIBNL_00425 6.59e-171 yjaU - - I - - - carboxylic ester hydrolase activity
NNAPIBNL_00426 7.04e-127 yjaV - - - - - - -
NNAPIBNL_00427 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NNAPIBNL_00428 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NNAPIBNL_00429 1.46e-37 yjzB - - - - - - -
NNAPIBNL_00430 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNAPIBNL_00431 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNAPIBNL_00432 2.47e-179 yjaZ - - O - - - Zn-dependent protease
NNAPIBNL_00433 1.81e-226 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_00434 4.48e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_00435 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NNAPIBNL_00436 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_00437 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_00438 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
NNAPIBNL_00439 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NNAPIBNL_00440 4.88e-162 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNAPIBNL_00441 3.06e-212 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNAPIBNL_00442 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_00443 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_00444 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_00445 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_00446 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
NNAPIBNL_00447 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNAPIBNL_00448 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNAPIBNL_00449 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
NNAPIBNL_00450 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNAPIBNL_00451 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
NNAPIBNL_00452 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NNAPIBNL_00453 3.14e-27 - - - - - - - -
NNAPIBNL_00454 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NNAPIBNL_00455 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NNAPIBNL_00456 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNAPIBNL_00457 8.1e-118 yjbK - - S - - - protein conserved in bacteria
NNAPIBNL_00458 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
NNAPIBNL_00459 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NNAPIBNL_00460 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNAPIBNL_00461 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNAPIBNL_00462 1.1e-176 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NNAPIBNL_00463 1.5e-108 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNAPIBNL_00464 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NNAPIBNL_00465 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NNAPIBNL_00466 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NNAPIBNL_00467 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
NNAPIBNL_00468 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NNAPIBNL_00469 7.09e-228 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNAPIBNL_00470 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNAPIBNL_00471 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NNAPIBNL_00472 2.47e-100 yjbX - - S - - - Spore coat protein
NNAPIBNL_00473 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NNAPIBNL_00474 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NNAPIBNL_00475 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NNAPIBNL_00476 1.02e-36 cotW - - - ko:K06341 - ko00000 -
NNAPIBNL_00477 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NNAPIBNL_00478 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
NNAPIBNL_00481 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNAPIBNL_00482 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
NNAPIBNL_00483 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNAPIBNL_00484 1.62e-44 - - - - - - - -
NNAPIBNL_00485 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NNAPIBNL_00486 2e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNAPIBNL_00487 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNAPIBNL_00488 1.19e-45 - - - K - - - SpoVT / AbrB like domain
NNAPIBNL_00489 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNAPIBNL_00490 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NNAPIBNL_00491 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NNAPIBNL_00492 3.46e-265 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNAPIBNL_00493 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNAPIBNL_00495 2.89e-73 - - - - - - - -
NNAPIBNL_00496 2.31e-90 - - - S - - - Bacterial EndoU nuclease
NNAPIBNL_00497 1.06e-42 - - - - - - - -
NNAPIBNL_00498 3.75e-116 yokH - - G - - - SMI1 / KNR4 family
NNAPIBNL_00499 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
NNAPIBNL_00500 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
NNAPIBNL_00501 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
NNAPIBNL_00503 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
NNAPIBNL_00504 2.8e-119 - - - K - - - Psort location Cytoplasmic, score
NNAPIBNL_00505 3.84e-226 - - - K - - - Psort location Cytoplasmic, score
NNAPIBNL_00506 9.18e-49 - - - S - - - YolD-like protein
NNAPIBNL_00507 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNAPIBNL_00508 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
NNAPIBNL_00512 0.000667 KLHL36 - - T ko:K13958 - ko00000,ko04121 protein modification by small protein conjugation
NNAPIBNL_00513 4.57e-21 - - - N - - - Kelch motif
NNAPIBNL_00515 3.78e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NNAPIBNL_00516 7.1e-58 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NNAPIBNL_00517 1.22e-280 yfjF - - EGP - - - Belongs to the major facilitator superfamily
NNAPIBNL_00518 3.15e-67 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00519 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NNAPIBNL_00520 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
NNAPIBNL_00521 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NNAPIBNL_00522 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NNAPIBNL_00523 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_00524 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
NNAPIBNL_00525 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNAPIBNL_00528 1.03e-314 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNAPIBNL_00529 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_00530 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_00531 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00532 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NNAPIBNL_00533 8.06e-313 ycnB - - EGP - - - the major facilitator superfamily
NNAPIBNL_00534 4.78e-192 ycnC - - K - - - Transcriptional regulator
NNAPIBNL_00535 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
NNAPIBNL_00536 2.79e-59 ycnE - - S - - - Monooxygenase
NNAPIBNL_00537 1.08e-67 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NNAPIBNL_00538 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNAPIBNL_00539 3.02e-278 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNAPIBNL_00540 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNAPIBNL_00541 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NNAPIBNL_00542 3.14e-182 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_00543 6.58e-128 ycnI - - S - - - protein conserved in bacteria
NNAPIBNL_00544 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NNAPIBNL_00545 1.15e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNAPIBNL_00546 2.18e-69 - - - - - - - -
NNAPIBNL_00547 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NNAPIBNL_00548 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NNAPIBNL_00549 2.79e-255 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NNAPIBNL_00550 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NNAPIBNL_00552 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NNAPIBNL_00553 8.23e-170 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NNAPIBNL_00554 6.98e-267 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NNAPIBNL_00555 3.25e-181 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NNAPIBNL_00556 1.68e-168 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NNAPIBNL_00557 5.16e-226 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NNAPIBNL_00558 7.07e-162 kipR - - K - - - Transcriptional regulator
NNAPIBNL_00559 9.77e-144 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NNAPIBNL_00561 6.7e-72 yczJ - - S - - - biosynthesis
NNAPIBNL_00562 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NNAPIBNL_00563 7.28e-212 ycsN - - S - - - Oxidoreductase
NNAPIBNL_00564 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NNAPIBNL_00565 0.0 ydaB - - IQ - - - acyl-CoA ligase
NNAPIBNL_00566 6.33e-182 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_00567 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NNAPIBNL_00568 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNAPIBNL_00569 4.32e-100 ydaG - - S - - - general stress protein
NNAPIBNL_00570 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NNAPIBNL_00571 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NNAPIBNL_00572 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NNAPIBNL_00573 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNAPIBNL_00574 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NNAPIBNL_00575 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NNAPIBNL_00576 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NNAPIBNL_00577 1.2e-298 ydaM - - M - - - Glycosyl transferase family group 2
NNAPIBNL_00578 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NNAPIBNL_00579 0.0 ydaO - - E - - - amino acid
NNAPIBNL_00580 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NNAPIBNL_00581 5.03e-80 - - - K - - - acetyltransferase
NNAPIBNL_00582 1.49e-100 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NNAPIBNL_00583 1.04e-83 - - - - - - - -
NNAPIBNL_00584 1.77e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NNAPIBNL_00587 1.06e-53 - - - - - - - -
NNAPIBNL_00588 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NNAPIBNL_00591 4.61e-44 ydaT - - - - - - -
NNAPIBNL_00592 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NNAPIBNL_00593 2.83e-63 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NNAPIBNL_00594 6.45e-174 ydbA - - P - - - EcsC protein family
NNAPIBNL_00595 1.04e-75 ydbB - - G - - - Cupin domain
NNAPIBNL_00596 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
NNAPIBNL_00597 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
NNAPIBNL_00598 8.49e-52 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NNAPIBNL_00599 2.07e-171 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NNAPIBNL_00600 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNAPIBNL_00601 2.66e-146 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NNAPIBNL_00602 3.75e-285 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNAPIBNL_00603 1.85e-225 ydbI - - S - - - AI-2E family transporter
NNAPIBNL_00604 1.79e-216 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_00605 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNAPIBNL_00606 1.32e-69 ydbL - - - - - - -
NNAPIBNL_00607 7.84e-256 ydbM - - I - - - acyl-CoA dehydrogenase
NNAPIBNL_00608 2.36e-17 - - - S - - - Fur-regulated basic protein B
NNAPIBNL_00609 6.11e-15 - - - S - - - Fur-regulated basic protein A
NNAPIBNL_00610 1.34e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNAPIBNL_00611 2.25e-74 ydbP - - CO - - - Thioredoxin
NNAPIBNL_00612 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NNAPIBNL_00613 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNAPIBNL_00614 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNAPIBNL_00615 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NNAPIBNL_00616 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NNAPIBNL_00617 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NNAPIBNL_00618 4.96e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNAPIBNL_00619 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NNAPIBNL_00620 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNAPIBNL_00621 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NNAPIBNL_00622 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NNAPIBNL_00623 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NNAPIBNL_00624 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NNAPIBNL_00625 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NNAPIBNL_00626 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NNAPIBNL_00627 1.34e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NNAPIBNL_00628 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NNAPIBNL_00629 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_00630 3.58e-135 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NNAPIBNL_00631 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NNAPIBNL_00632 1.78e-21 - - - - - - - -
NNAPIBNL_00633 4.1e-74 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NNAPIBNL_00641 5.14e-10 - - - S - - - YvrJ protein family
NNAPIBNL_00642 4.24e-62 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_00646 4.65e-40 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NNAPIBNL_00649 6.4e-31 - - - S - - - YesK-like protein
NNAPIBNL_00650 1.31e-246 ydcL - - L - - - Belongs to the 'phage' integrase family
NNAPIBNL_00651 9.84e-80 - - - E - - - Pfam:DUF955
NNAPIBNL_00652 4.29e-71 - - - K - - - Transcriptional
NNAPIBNL_00653 2.18e-34 - - - - - - - -
NNAPIBNL_00655 1.87e-50 - - - S - - - Bacterial protein of unknown function (DUF961)
NNAPIBNL_00657 1.56e-302 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
NNAPIBNL_00658 7.64e-231 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NNAPIBNL_00662 8.19e-49 yddA - - - - - - -
NNAPIBNL_00666 7.38e-165 yddB - - S - - - Conjugative transposon protein TcpC
NNAPIBNL_00667 2.72e-33 yddC - - - - - - -
NNAPIBNL_00668 1.85e-97 yddD - - S - - - TcpE family
NNAPIBNL_00669 0.0 yddE - - S - - - AAA-like domain
NNAPIBNL_00670 1.37e-47 - - - S - - - Domain of unknown function (DUF1874)
NNAPIBNL_00671 6.43e-261 yddG - - S - - - maturation of SSU-rRNA
NNAPIBNL_00672 1.46e-200 yddH - - M - - - Lysozyme-like
NNAPIBNL_00673 1.89e-73 yddI - - - - - - -
NNAPIBNL_00674 4.28e-47 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NNAPIBNL_00675 4.06e-75 - - - - - - - -
NNAPIBNL_00679 1.41e-181 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NNAPIBNL_00680 7.54e-91 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NNAPIBNL_00682 1.5e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNAPIBNL_00683 2.4e-253 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNAPIBNL_00684 7.99e-71 - - - - - - - -
NNAPIBNL_00685 1.19e-99 - - - K - - - Transcriptional regulator
NNAPIBNL_00686 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNAPIBNL_00687 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NNAPIBNL_00688 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNAPIBNL_00689 1e-131 - - - S - - - Protein of unknown function (DUF2812)
NNAPIBNL_00690 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
NNAPIBNL_00691 1.99e-300 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNAPIBNL_00692 3.96e-238 ydeG - - EGP - - - Major facilitator superfamily
NNAPIBNL_00693 1.41e-63 - - - S - - - Patatin-like phospholipase
NNAPIBNL_00694 5.81e-57 - - - S - - - Patatin-like phospholipase
NNAPIBNL_00696 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NNAPIBNL_00697 2.6e-90 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_00698 8.48e-196 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NNAPIBNL_00699 3.58e-201 - - - S - - - SNARE associated Golgi protein
NNAPIBNL_00700 1.19e-124 yrkC - - G - - - Cupin domain
NNAPIBNL_00701 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NNAPIBNL_00702 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NNAPIBNL_00704 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NNAPIBNL_00705 7.14e-63 ydeH - - - - - - -
NNAPIBNL_00706 3.65e-206 - - - S - - - Sodium Bile acid symporter family
NNAPIBNL_00707 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NNAPIBNL_00708 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NNAPIBNL_00709 6.33e-278 nhaC_1 - - C - - - antiporter
NNAPIBNL_00710 1.34e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NNAPIBNL_00711 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_00712 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NNAPIBNL_00713 2.13e-129 ydeS - - K - - - Transcriptional regulator
NNAPIBNL_00714 2.99e-192 ydeK - - EG - - - -transporter
NNAPIBNL_00715 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNAPIBNL_00716 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
NNAPIBNL_00717 4.86e-33 yraE - - - ko:K06440 - ko00000 -
NNAPIBNL_00718 3.27e-277 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNAPIBNL_00719 4.76e-84 yraF - - M - - - Spore coat protein
NNAPIBNL_00720 4.73e-47 yraG - - - ko:K06440 - ko00000 -
NNAPIBNL_00721 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NNAPIBNL_00722 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NNAPIBNL_00723 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NNAPIBNL_00724 4.32e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
NNAPIBNL_00725 1.37e-188 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_00726 3.1e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NNAPIBNL_00727 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NNAPIBNL_00728 4.68e-280 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNAPIBNL_00729 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_00730 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NNAPIBNL_00731 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NNAPIBNL_00732 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
NNAPIBNL_00733 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NNAPIBNL_00734 1.15e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NNAPIBNL_00735 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
NNAPIBNL_00736 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NNAPIBNL_00737 1.47e-144 ydhC - - K - - - FCD
NNAPIBNL_00738 8.62e-69 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNAPIBNL_00739 1.11e-168 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNAPIBNL_00741 3.98e-311 pbpE - - V - - - Beta-lactamase
NNAPIBNL_00743 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
NNAPIBNL_00744 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NNAPIBNL_00745 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NNAPIBNL_00746 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
NNAPIBNL_00747 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NNAPIBNL_00748 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NNAPIBNL_00749 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNAPIBNL_00750 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
NNAPIBNL_00751 0.0 ybeC - - E - - - amino acid
NNAPIBNL_00752 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
NNAPIBNL_00753 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NNAPIBNL_00754 3.55e-39 csfB - - S - - - Inhibitor of sigma-G Gin
NNAPIBNL_00755 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NNAPIBNL_00756 6.32e-226 yaaN - - P - - - Belongs to the TelA family
NNAPIBNL_00757 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NNAPIBNL_00758 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNAPIBNL_00759 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
NNAPIBNL_00760 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NNAPIBNL_00761 8.67e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NNAPIBNL_00762 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NNAPIBNL_00763 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
NNAPIBNL_00764 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NNAPIBNL_00765 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NNAPIBNL_00766 9.82e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNAPIBNL_00767 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NNAPIBNL_00768 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNAPIBNL_00769 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NNAPIBNL_00770 3.55e-288 yabE - - T - - - protein conserved in bacteria
NNAPIBNL_00771 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNAPIBNL_00772 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNAPIBNL_00773 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
NNAPIBNL_00774 5.32e-53 veg - - S - - - protein conserved in bacteria
NNAPIBNL_00775 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
NNAPIBNL_00776 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNAPIBNL_00777 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NNAPIBNL_00778 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NNAPIBNL_00779 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NNAPIBNL_00780 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNAPIBNL_00781 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNAPIBNL_00782 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NNAPIBNL_00783 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNAPIBNL_00784 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
NNAPIBNL_00785 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNAPIBNL_00786 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NNAPIBNL_00787 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_00788 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NNAPIBNL_00789 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NNAPIBNL_00790 5.47e-66 yabP - - S - - - Sporulation protein YabP
NNAPIBNL_00791 1.47e-128 yabQ - - S - - - spore cortex biosynthesis protein
NNAPIBNL_00792 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NNAPIBNL_00793 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NNAPIBNL_00796 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NNAPIBNL_00797 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNAPIBNL_00798 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNAPIBNL_00799 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNAPIBNL_00800 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NNAPIBNL_00801 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNAPIBNL_00802 5.46e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NNAPIBNL_00803 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNAPIBNL_00804 1.22e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NNAPIBNL_00805 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNAPIBNL_00806 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNAPIBNL_00807 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NNAPIBNL_00808 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NNAPIBNL_00809 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NNAPIBNL_00810 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NNAPIBNL_00811 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NNAPIBNL_00812 9.99e-39 yazB - - K - - - transcriptional
NNAPIBNL_00813 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNAPIBNL_00814 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NNAPIBNL_00815 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NNAPIBNL_00816 5.64e-150 - - - S - - - Phage tail protein
NNAPIBNL_00817 0.0 - - - D - - - Phage tail tape measure protein
NNAPIBNL_00819 1.62e-42 - - - S - - - Phage tail tube protein
NNAPIBNL_00821 2.31e-46 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNAPIBNL_00822 1.05e-40 - - - S - - - Phage head-tail joining protein
NNAPIBNL_00823 5.7e-11 - - - S - - - Phage gp6-like head-tail connector protein
NNAPIBNL_00824 2.56e-32 - - - - - - - -
NNAPIBNL_00825 4.2e-161 - - - S - - - capsid protein
NNAPIBNL_00826 1.69e-95 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NNAPIBNL_00827 8.49e-220 - - - S - - - portal protein
NNAPIBNL_00829 0.0 terL - - S - - - Terminase
NNAPIBNL_00830 4.02e-79 - - - L - - - Terminase, small subunit
NNAPIBNL_00832 4.27e-64 - - - - - - - -
NNAPIBNL_00833 2.16e-287 - - - KL - - - SNF2 family N-terminal domain
NNAPIBNL_00834 1.19e-20 - - - S - - - VRR-NUC domain protein
NNAPIBNL_00835 0.0 - - - L - - - Virulence-associated protein E
NNAPIBNL_00837 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
NNAPIBNL_00838 1.89e-08 - - - - - - - -
NNAPIBNL_00839 5.24e-111 - - - S - - - Protein of unknown function (DUF2815)
NNAPIBNL_00841 4.06e-204 - - - L - - - Protein of unknown function (DUF2800)
NNAPIBNL_00842 5.63e-16 - - - - - - - -
NNAPIBNL_00843 1.52e-58 - - - - - - - -
NNAPIBNL_00845 1.14e-44 - - - S - - - Uncharacterized protein YqaH
NNAPIBNL_00847 1.05e-40 - - - - - - - -
NNAPIBNL_00848 2.73e-26 - - - - - - - -
NNAPIBNL_00849 3.84e-70 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNAPIBNL_00850 1.98e-70 - - - E - - - IrrE N-terminal-like domain
NNAPIBNL_00851 3.02e-191 - - - S - - - Pfam:Arm-DNA-bind_4
NNAPIBNL_00852 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NNAPIBNL_00853 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NNAPIBNL_00854 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNAPIBNL_00855 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NNAPIBNL_00856 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NNAPIBNL_00858 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NNAPIBNL_00859 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NNAPIBNL_00860 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NNAPIBNL_00861 1.51e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNAPIBNL_00862 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
NNAPIBNL_00863 2.25e-70 yusE - - CO - - - Thioredoxin
NNAPIBNL_00864 5.93e-30 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NNAPIBNL_00865 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
NNAPIBNL_00866 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NNAPIBNL_00867 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NNAPIBNL_00868 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NNAPIBNL_00869 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NNAPIBNL_00870 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NNAPIBNL_00871 1.72e-10 - - - S - - - YuzL-like protein
NNAPIBNL_00872 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NNAPIBNL_00873 7.03e-53 - - - - - - - -
NNAPIBNL_00874 3.53e-69 yusN - - M - - - Coat F domain
NNAPIBNL_00875 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NNAPIBNL_00876 0.0 yusP - - P - - - Major facilitator superfamily
NNAPIBNL_00877 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
NNAPIBNL_00878 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_00879 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NNAPIBNL_00880 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
NNAPIBNL_00881 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNAPIBNL_00882 2.79e-62 - - - S - - - YusW-like protein
NNAPIBNL_00883 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NNAPIBNL_00884 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_00885 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NNAPIBNL_00886 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNAPIBNL_00887 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_00888 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_00889 2.68e-32 - - - - - - - -
NNAPIBNL_00890 6.7e-196 yuxN - - K - - - Transcriptional regulator
NNAPIBNL_00891 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNAPIBNL_00892 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
NNAPIBNL_00893 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NNAPIBNL_00894 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NNAPIBNL_00895 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NNAPIBNL_00896 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNAPIBNL_00897 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_00898 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NNAPIBNL_00899 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NNAPIBNL_00900 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NNAPIBNL_00901 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NNAPIBNL_00902 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_00903 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NNAPIBNL_00904 5.35e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NNAPIBNL_00905 5.73e-224 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_00906 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNAPIBNL_00907 9.76e-122 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NNAPIBNL_00908 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
NNAPIBNL_00910 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NNAPIBNL_00911 7.91e-83 ydjM - - M - - - Lytic transglycolase
NNAPIBNL_00912 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NNAPIBNL_00913 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_00914 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
NNAPIBNL_00915 0.0 oatA - - I - - - Acyltransferase family
NNAPIBNL_00916 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NNAPIBNL_00917 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NNAPIBNL_00918 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNAPIBNL_00919 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NNAPIBNL_00920 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
NNAPIBNL_00921 3.16e-211 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NNAPIBNL_00922 9.02e-311 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NNAPIBNL_00923 1.55e-251 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NNAPIBNL_00924 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NNAPIBNL_00925 2.21e-81 - - - - - - - -
NNAPIBNL_00927 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
NNAPIBNL_00930 2e-155 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNAPIBNL_00931 2.07e-37 xhlB - - S - - - SPP1 phage holin
NNAPIBNL_00932 1.19e-40 xhlA - - S - - - Haemolysin XhlA
NNAPIBNL_00936 2.51e-246 - - - L - - - Phage minor structural protein
NNAPIBNL_00938 3.59e-186 - - - - - - - -
NNAPIBNL_00940 3.23e-44 - - - S - - - Phage tail tube protein
NNAPIBNL_00941 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
NNAPIBNL_00942 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNAPIBNL_00943 7.37e-38 - - - S - - - Phage head-tail joining protein
NNAPIBNL_00944 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
NNAPIBNL_00947 1.85e-61 - - - S - - - viral capsid
NNAPIBNL_00948 3.82e-56 - - - S - - - Phage minor structural protein GP20
NNAPIBNL_00950 1.53e-116 - - - S - - - Phage Mu protein F like protein
NNAPIBNL_00951 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
NNAPIBNL_00952 9.66e-225 - - - S - - - Pfam:Terminase_3C
NNAPIBNL_00953 7.49e-103 yqaS - - L - - - DNA packaging
NNAPIBNL_00956 1.74e-17 - - - K - - - Transcriptional regulator
NNAPIBNL_00958 5.88e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NNAPIBNL_00959 1.76e-22 - - - V - - - VanZ like family
NNAPIBNL_00961 3.27e-63 - - - - - - - -
NNAPIBNL_00966 2.62e-08 - - - S - - - YopX protein
NNAPIBNL_00969 2.08e-54 - - - S - - - dUTPase
NNAPIBNL_00971 4.72e-217 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NNAPIBNL_00974 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
NNAPIBNL_00976 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
NNAPIBNL_00977 5.52e-28 - - - S - - - YopX protein
NNAPIBNL_00979 1.54e-152 yqaM - - L - - - IstB-like ATP binding protein
NNAPIBNL_00980 4.55e-36 yqaL - - L - - - DnaD domain protein
NNAPIBNL_00981 3.37e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NNAPIBNL_00982 6.89e-72 yqaJ - - L - - - YqaJ-like viral recombinase domain
NNAPIBNL_00983 2.37e-98 yqaJ - - L - - - YqaJ-like viral recombinase domain
NNAPIBNL_00987 3.27e-110 - - - - - - - -
NNAPIBNL_00988 4.76e-76 - - - S - - - DNA binding
NNAPIBNL_00989 2.39e-48 - - - - - - - -
NNAPIBNL_00990 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_00991 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_00992 8.41e-82 - - - - - - - -
NNAPIBNL_00993 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
NNAPIBNL_00994 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
NNAPIBNL_00995 1.16e-43 - - - L - - - Arm DNA-binding domain
NNAPIBNL_00996 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNAPIBNL_00997 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNAPIBNL_00998 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NNAPIBNL_00999 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NNAPIBNL_01000 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNAPIBNL_01001 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNAPIBNL_01002 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNAPIBNL_01003 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NNAPIBNL_01004 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NNAPIBNL_01005 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNAPIBNL_01006 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NNAPIBNL_01007 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NNAPIBNL_01008 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NNAPIBNL_01009 3.49e-183 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NNAPIBNL_01015 1.83e-60 - - - S - - - YfzA-like protein
NNAPIBNL_01016 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNAPIBNL_01017 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
NNAPIBNL_01018 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNAPIBNL_01019 4.01e-237 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNAPIBNL_01020 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNAPIBNL_01021 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNAPIBNL_01022 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NNAPIBNL_01023 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NNAPIBNL_01024 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNAPIBNL_01025 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NNAPIBNL_01026 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_01027 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
NNAPIBNL_01028 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNAPIBNL_01029 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNAPIBNL_01030 7.86e-82 yfiD3 - - S - - - DoxX
NNAPIBNL_01031 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NNAPIBNL_01032 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNAPIBNL_01033 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNAPIBNL_01034 1e-119 padR - - K - - - transcriptional
NNAPIBNL_01035 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNAPIBNL_01036 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NNAPIBNL_01037 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NNAPIBNL_01038 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NNAPIBNL_01039 0.0 yfiU - - EGP - - - the major facilitator superfamily
NNAPIBNL_01040 2.11e-103 yfiV - - K - - - transcriptional
NNAPIBNL_01041 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNAPIBNL_01042 1.27e-193 yfhB - - S - - - PhzF family
NNAPIBNL_01043 3.09e-133 yfhC - - C - - - nitroreductase
NNAPIBNL_01044 6.01e-33 yfhD - - S - - - YfhD-like protein
NNAPIBNL_01046 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NNAPIBNL_01047 2.77e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NNAPIBNL_01048 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
NNAPIBNL_01049 6.7e-231 yfhI - - EGP - - - -transporter
NNAPIBNL_01051 6.34e-201 mpr - - M - - - Belongs to the peptidase S1B family
NNAPIBNL_01052 1.49e-58 yfhJ - - S - - - WVELL protein
NNAPIBNL_01053 2.3e-112 yfhK - - T - - - Bacterial SH3 domain homologues
NNAPIBNL_01054 3.3e-10 yfhL - - S - - - SdpI/YhfL protein family
NNAPIBNL_01055 1.29e-23 yfhL - - S - - - SdpI/YhfL protein family
NNAPIBNL_01056 8.86e-119 - - - S - - - Alpha/beta hydrolase family
NNAPIBNL_01057 1.29e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNAPIBNL_01058 2.79e-114 yfhO - - S - - - Bacterial membrane protein YfhO
NNAPIBNL_01059 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NNAPIBNL_01060 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NNAPIBNL_01061 8.93e-173 - - - L - - - Belongs to the 'phage' integrase family
NNAPIBNL_01062 3.01e-56 - - - E - - - Zn peptidase
NNAPIBNL_01063 7.33e-43 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_01064 3.24e-24 - - - - - - - -
NNAPIBNL_01065 3.79e-39 - - - - - - - -
NNAPIBNL_01068 1.37e-89 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
NNAPIBNL_01071 8.43e-111 - - - L - - - DnaD domain protein
NNAPIBNL_01072 1.06e-19 - - - S - - - Loader and inhibitor of phage G40P
NNAPIBNL_01073 1.22e-210 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
NNAPIBNL_01074 1.36e-33 - - - - - - - -
NNAPIBNL_01079 7.95e-37 - - - S - - - Phage-like element PBSX protein XtrA
NNAPIBNL_01080 9.73e-103 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NNAPIBNL_01081 9.43e-62 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
NNAPIBNL_01082 1.87e-26 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
NNAPIBNL_01086 1.72e-42 - - - V - - - HNH nucleases
NNAPIBNL_01087 2.92e-61 - - - L - - - Phage terminase, small subunit
NNAPIBNL_01088 0.0 - - - S - - - Terminase
NNAPIBNL_01089 2.18e-86 - - - S - - - Phage portal protein
NNAPIBNL_01090 1.1e-87 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NNAPIBNL_01091 3.41e-145 - - - S - - - Phage capsid family
NNAPIBNL_01098 8.45e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NNAPIBNL_01099 3e-22 - - - - - - - -
NNAPIBNL_01100 0.0 ywqB - - S - - - SWIM zinc finger
NNAPIBNL_01101 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNAPIBNL_01102 1.28e-193 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NNAPIBNL_01103 5.39e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NNAPIBNL_01104 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NNAPIBNL_01105 1.83e-74 ywpG - - - - - - -
NNAPIBNL_01106 1.79e-89 ywpF - - S - - - YwpF-like protein
NNAPIBNL_01107 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNAPIBNL_01108 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNAPIBNL_01109 4.41e-247 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NNAPIBNL_01110 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NNAPIBNL_01111 3.86e-18 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NNAPIBNL_01112 5.61e-138 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NNAPIBNL_01113 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NNAPIBNL_01114 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NNAPIBNL_01115 5.3e-93 ywoH - - K - - - transcriptional
NNAPIBNL_01116 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_01117 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NNAPIBNL_01118 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
NNAPIBNL_01119 2.1e-128 yjgF - - Q - - - Isochorismatase family
NNAPIBNL_01120 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NNAPIBNL_01121 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NNAPIBNL_01122 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNAPIBNL_01123 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NNAPIBNL_01124 3.41e-88 ywnJ - - S - - - VanZ like family
NNAPIBNL_01125 1.67e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NNAPIBNL_01126 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NNAPIBNL_01128 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
NNAPIBNL_01129 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNAPIBNL_01130 1.12e-21 yqgA - - - - - - -
NNAPIBNL_01131 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
NNAPIBNL_01132 2.16e-115 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NNAPIBNL_01133 3.09e-88 ywnA - - K - - - Transcriptional regulator
NNAPIBNL_01134 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NNAPIBNL_01135 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NNAPIBNL_01136 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NNAPIBNL_01137 2.41e-16 csbD - - K - - - CsbD-like
NNAPIBNL_01138 1.01e-105 ywmF - - S - - - Peptidase M50
NNAPIBNL_01139 2.67e-112 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NNAPIBNL_01140 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NNAPIBNL_01141 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NNAPIBNL_01143 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNAPIBNL_01144 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NNAPIBNL_01145 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NNAPIBNL_01146 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNAPIBNL_01147 1.64e-161 ywmB - - S - - - TATA-box binding
NNAPIBNL_01148 1.85e-44 ywzB - - S - - - membrane
NNAPIBNL_01149 1.98e-115 ywmA - - - - - - -
NNAPIBNL_01150 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NNAPIBNL_01151 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNAPIBNL_01152 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNAPIBNL_01153 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNAPIBNL_01154 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNAPIBNL_01155 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNAPIBNL_01156 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNAPIBNL_01157 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NNAPIBNL_01158 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NNAPIBNL_01159 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNAPIBNL_01160 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNAPIBNL_01161 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
NNAPIBNL_01162 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NNAPIBNL_01163 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNAPIBNL_01164 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
NNAPIBNL_01165 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNAPIBNL_01166 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NNAPIBNL_01167 7.05e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NNAPIBNL_01168 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NNAPIBNL_01170 1.18e-194 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNAPIBNL_01171 8.38e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNAPIBNL_01172 6.91e-84 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_01173 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NNAPIBNL_01174 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NNAPIBNL_01175 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NNAPIBNL_01176 3.09e-129 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NNAPIBNL_01177 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NNAPIBNL_01178 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NNAPIBNL_01179 6.51e-221 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NNAPIBNL_01180 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNAPIBNL_01181 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NNAPIBNL_01182 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NNAPIBNL_01183 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NNAPIBNL_01184 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
NNAPIBNL_01185 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNAPIBNL_01186 1.53e-71 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNAPIBNL_01187 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NNAPIBNL_01188 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NNAPIBNL_01189 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NNAPIBNL_01190 3.23e-58 ywjC - - - - - - -
NNAPIBNL_01191 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NNAPIBNL_01192 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNAPIBNL_01193 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NNAPIBNL_01194 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NNAPIBNL_01195 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NNAPIBNL_01196 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNAPIBNL_01197 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NNAPIBNL_01198 8.59e-162 ywiC - - S - - - YwiC-like protein
NNAPIBNL_01199 1.67e-161 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NNAPIBNL_01200 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NNAPIBNL_01201 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NNAPIBNL_01202 4.46e-94 ywiB - - S - - - protein conserved in bacteria
NNAPIBNL_01204 8.63e-110 ywhL - - CO - - - amine dehydrogenase activity
NNAPIBNL_01205 2.22e-123 ywhK - - CO - - - amine dehydrogenase activity
NNAPIBNL_01206 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNAPIBNL_01208 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NNAPIBNL_01209 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NNAPIBNL_01210 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNAPIBNL_01211 1.96e-93 - - - - - - - -
NNAPIBNL_01212 2.07e-116 ywhD - - S - - - YwhD family
NNAPIBNL_01213 1.29e-151 ywhC - - S - - - Peptidase family M50
NNAPIBNL_01214 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NNAPIBNL_01215 3.29e-90 ywhA - - K - - - Transcriptional regulator
NNAPIBNL_01216 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
NNAPIBNL_01217 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
NNAPIBNL_01218 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NNAPIBNL_01219 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NNAPIBNL_01220 3.27e-136 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NNAPIBNL_01221 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
NNAPIBNL_01222 2.51e-109 - - - S - - - membrane
NNAPIBNL_01223 1.93e-194 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_01224 2.13e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
NNAPIBNL_01227 2.83e-120 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NNAPIBNL_01228 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NNAPIBNL_01229 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NNAPIBNL_01230 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NNAPIBNL_01231 1.15e-158 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NNAPIBNL_01232 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NNAPIBNL_01233 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NNAPIBNL_01234 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NNAPIBNL_01235 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NNAPIBNL_01236 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NNAPIBNL_01237 9.05e-78 - - - K - - - Collagen triple helix repeat
NNAPIBNL_01238 2.15e-260 - - - M - - - Glycosyl transferase family 2
NNAPIBNL_01240 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NNAPIBNL_01241 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
NNAPIBNL_01242 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
NNAPIBNL_01243 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
NNAPIBNL_01244 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNAPIBNL_01245 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNAPIBNL_01246 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NNAPIBNL_01247 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NNAPIBNL_01248 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NNAPIBNL_01249 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NNAPIBNL_01250 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
NNAPIBNL_01251 1.45e-179 ykgA - - E - - - Amidinotransferase
NNAPIBNL_01252 6.11e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NNAPIBNL_01253 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_01254 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNAPIBNL_01255 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NNAPIBNL_01256 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NNAPIBNL_01257 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NNAPIBNL_01258 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_01259 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_01260 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_01261 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NNAPIBNL_01262 0.0 yubD - - P - - - Major Facilitator Superfamily
NNAPIBNL_01263 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNAPIBNL_01265 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNAPIBNL_01266 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NNAPIBNL_01267 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNAPIBNL_01268 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
NNAPIBNL_01269 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NNAPIBNL_01270 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
NNAPIBNL_01271 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NNAPIBNL_01272 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NNAPIBNL_01273 2.43e-206 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_01274 2.62e-49 xhlB - - S - - - SPP1 phage holin
NNAPIBNL_01275 6.44e-50 xhlA - - S - - - Haemolysin XhlA
NNAPIBNL_01276 2.97e-167 xepA - - - - - - -
NNAPIBNL_01277 1.05e-36 xkdX - - - - - - -
NNAPIBNL_01279 1.04e-194 - - - - - - - -
NNAPIBNL_01280 1.48e-36 - - - - - - - -
NNAPIBNL_01281 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NNAPIBNL_01282 7.44e-208 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NNAPIBNL_01283 2.35e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
NNAPIBNL_01284 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
NNAPIBNL_01285 2.78e-208 xkdQ - - G - - - NLP P60 protein
NNAPIBNL_01286 1.88e-144 xkdP - - S - - - Lysin motif
NNAPIBNL_01287 7.01e-277 xkdO - - L - - - Transglycosylase SLT domain
NNAPIBNL_01288 4.33e-27 - - - - - - - -
NNAPIBNL_01289 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NNAPIBNL_01290 8.21e-97 xkdM - - S - - - Phage tail tube protein
NNAPIBNL_01291 4.44e-285 xkdK - - S - - - Phage tail sheath C-terminal domain
NNAPIBNL_01292 3.86e-21 - - - - - - - -
NNAPIBNL_01293 1.82e-75 xkdJ - - - - - - -
NNAPIBNL_01294 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNAPIBNL_01296 3.38e-202 xkdG - - S - - - Phage capsid family
NNAPIBNL_01297 6.92e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
NNAPIBNL_01298 1.72e-302 xkdE3 - - S - - - portal protein
NNAPIBNL_01299 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NNAPIBNL_01300 1.37e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NNAPIBNL_01301 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NNAPIBNL_01305 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
NNAPIBNL_01307 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_01308 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
NNAPIBNL_01309 2.69e-128 yjqB - - S - - - phage-related replication protein
NNAPIBNL_01310 3.19e-79 yjqA - - S - - - Bacterial PH domain
NNAPIBNL_01311 5.72e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNAPIBNL_01313 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NNAPIBNL_01314 9.4e-100 yjoA - - S - - - DinB family
NNAPIBNL_01315 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NNAPIBNL_01317 2.12e-165 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NNAPIBNL_01318 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
NNAPIBNL_01319 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NNAPIBNL_01320 1.62e-231 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NNAPIBNL_01321 2.92e-80 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NNAPIBNL_01322 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNAPIBNL_01323 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NNAPIBNL_01324 1.47e-110 yjlB - - S - - - Cupin domain
NNAPIBNL_01325 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NNAPIBNL_01326 4.94e-42 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_01327 1.44e-65 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNAPIBNL_01328 4.85e-98 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNAPIBNL_01329 5.21e-88 yjgD - - S - - - Protein of unknown function (DUF1641)
NNAPIBNL_01330 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNAPIBNL_01331 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NNAPIBNL_01332 1.73e-40 - - - - - - - -
NNAPIBNL_01333 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NNAPIBNL_01334 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NNAPIBNL_01335 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNAPIBNL_01336 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
NNAPIBNL_01337 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
NNAPIBNL_01338 1.07e-28 yjfB - - S - - - Putative motility protein
NNAPIBNL_01340 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NNAPIBNL_01341 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_01342 3.81e-45 - - - - - - - -
NNAPIBNL_01343 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
NNAPIBNL_01344 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NNAPIBNL_01345 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNAPIBNL_01346 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_01347 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNAPIBNL_01348 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NNAPIBNL_01349 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_01350 1.72e-171 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NNAPIBNL_01351 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NNAPIBNL_01352 2.74e-95 ypmB - - S - - - protein conserved in bacteria
NNAPIBNL_01353 1.1e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNAPIBNL_01354 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NNAPIBNL_01355 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NNAPIBNL_01356 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNAPIBNL_01357 4.6e-113 ypoC - - - - - - -
NNAPIBNL_01358 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNAPIBNL_01359 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNAPIBNL_01360 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
NNAPIBNL_01365 5.58e-60 yppG - - S - - - YppG-like protein
NNAPIBNL_01366 5.45e-79 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNAPIBNL_01367 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NNAPIBNL_01368 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NNAPIBNL_01369 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NNAPIBNL_01371 5.48e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NNAPIBNL_01372 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
NNAPIBNL_01373 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNAPIBNL_01374 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NNAPIBNL_01375 2.19e-96 yqgA - - - - - - -
NNAPIBNL_01376 6.91e-31 - - - S - - - YpzG-like protein
NNAPIBNL_01378 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NNAPIBNL_01379 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NNAPIBNL_01380 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNAPIBNL_01381 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
NNAPIBNL_01382 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
NNAPIBNL_01383 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NNAPIBNL_01384 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
NNAPIBNL_01385 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NNAPIBNL_01386 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NNAPIBNL_01387 0.0 ypbR - - S - - - Dynamin family
NNAPIBNL_01388 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
NNAPIBNL_01389 5.97e-11 - - - - - - - -
NNAPIBNL_01390 2.07e-204 ypcP - - L - - - 5'3' exonuclease
NNAPIBNL_01392 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NNAPIBNL_01393 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NNAPIBNL_01394 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NNAPIBNL_01395 6.37e-38 ypeQ - - S - - - Zinc-finger
NNAPIBNL_01396 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
NNAPIBNL_01397 4.27e-16 degR - - - - - - -
NNAPIBNL_01398 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NNAPIBNL_01399 1.01e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NNAPIBNL_01400 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NNAPIBNL_01402 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NNAPIBNL_01403 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NNAPIBNL_01404 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NNAPIBNL_01405 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NNAPIBNL_01406 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
NNAPIBNL_01407 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NNAPIBNL_01408 1.41e-142 ypjP - - S - - - YpjP-like protein
NNAPIBNL_01409 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNAPIBNL_01410 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNAPIBNL_01411 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNAPIBNL_01412 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NNAPIBNL_01413 1.54e-207 yplP - - K - - - Transcriptional regulator
NNAPIBNL_01414 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NNAPIBNL_01415 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
NNAPIBNL_01416 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NNAPIBNL_01417 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NNAPIBNL_01418 2.45e-122 ypmS - - S - - - protein conserved in bacteria
NNAPIBNL_01419 1.42e-88 ypoP - - K - - - transcriptional
NNAPIBNL_01420 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNAPIBNL_01421 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NNAPIBNL_01422 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNAPIBNL_01423 6.94e-262 yokA - - L - - - Recombinase
NNAPIBNL_01424 6.05e-22 - - - S - - - Regulatory protein YrvL
NNAPIBNL_01426 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
NNAPIBNL_01429 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNAPIBNL_01430 7.88e-267 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NNAPIBNL_01431 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NNAPIBNL_01432 1.08e-81 cgeA - - - ko:K06319 - ko00000 -
NNAPIBNL_01433 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
NNAPIBNL_01434 1.17e-286 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NNAPIBNL_01435 3.96e-176 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NNAPIBNL_01437 3.54e-83 - - - L - - - Bacterial transcription activator, effector binding domain
NNAPIBNL_01439 2.06e-297 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNAPIBNL_01440 1.49e-155 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNAPIBNL_01441 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNAPIBNL_01442 4.03e-315 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NNAPIBNL_01443 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NNAPIBNL_01444 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NNAPIBNL_01445 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
NNAPIBNL_01446 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
NNAPIBNL_01447 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_01448 1.18e-155 yodN - - - - - - -
NNAPIBNL_01450 1.97e-33 yozD - - S - - - YozD-like protein
NNAPIBNL_01451 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NNAPIBNL_01452 1.16e-72 yodL - - S - - - YodL-like
NNAPIBNL_01454 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NNAPIBNL_01455 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NNAPIBNL_01456 2.3e-30 yodI - - - - - - -
NNAPIBNL_01457 1.3e-123 yodH - - Q - - - Methyltransferase
NNAPIBNL_01458 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NNAPIBNL_01459 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_01460 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNAPIBNL_01461 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NNAPIBNL_01462 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNAPIBNL_01463 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
NNAPIBNL_01464 8.81e-212 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNAPIBNL_01465 1.12e-118 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NNAPIBNL_01466 6.14e-135 yodC - - C - - - nitroreductase
NNAPIBNL_01467 1.93e-69 yodB - - K - - - transcriptional
NNAPIBNL_01468 9.37e-83 iolK - - S - - - tautomerase
NNAPIBNL_01470 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NNAPIBNL_01471 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NNAPIBNL_01472 3.66e-31 - - - - - - - -
NNAPIBNL_01473 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NNAPIBNL_01474 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NNAPIBNL_01475 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNAPIBNL_01476 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NNAPIBNL_01477 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNAPIBNL_01478 6.89e-278 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NNAPIBNL_01479 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNAPIBNL_01480 1.31e-135 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NNAPIBNL_01481 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NNAPIBNL_01482 0.0 yojO - - P - - - Von Willebrand factor
NNAPIBNL_01483 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NNAPIBNL_01484 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NNAPIBNL_01485 8.69e-156 - - - S - - - Metallo-beta-lactamase superfamily
NNAPIBNL_01486 3.02e-209 yocS - - S ko:K03453 - ko00000 -transporter
NNAPIBNL_01487 2.2e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNAPIBNL_01488 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NNAPIBNL_01489 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NNAPIBNL_01490 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNAPIBNL_01491 4.69e-43 yozC - - - - - - -
NNAPIBNL_01493 5.32e-75 yozO - - S - - - Bacterial PH domain
NNAPIBNL_01494 1.83e-49 yocN - - - - - - -
NNAPIBNL_01495 8.77e-41 yozN - - - - - - -
NNAPIBNL_01496 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NNAPIBNL_01497 1.16e-11 yocN - - - - - - -
NNAPIBNL_01499 7.44e-78 yocK - - T - - - general stress protein
NNAPIBNL_01500 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNAPIBNL_01502 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNAPIBNL_01503 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
NNAPIBNL_01505 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NNAPIBNL_01506 2.99e-119 yocC - - - - - - -
NNAPIBNL_01507 9.94e-172 - - - J - - - Protein required for attachment to host cells
NNAPIBNL_01508 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
NNAPIBNL_01509 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NNAPIBNL_01510 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NNAPIBNL_01511 1.29e-117 yobW - - - - - - -
NNAPIBNL_01512 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNAPIBNL_01513 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NNAPIBNL_01514 4.6e-119 yuaB - - - - - - -
NNAPIBNL_01515 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NNAPIBNL_01516 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNAPIBNL_01517 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NNAPIBNL_01518 2.36e-47 - - - G - - - Cupin
NNAPIBNL_01519 2.17e-57 yjcN - - - - - - -
NNAPIBNL_01522 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NNAPIBNL_01523 7.36e-20 - - - - - - - -
NNAPIBNL_01528 9.14e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNAPIBNL_01530 4.3e-54 - - - - - - - -
NNAPIBNL_01531 1.71e-304 - - - I - - - Pfam Lipase (class 3)
NNAPIBNL_01532 2.56e-67 - - - S - - - Protein of unknown function (DUF1433)
NNAPIBNL_01533 2.74e-21 - - - K - - - Helix-turn-helix domain
NNAPIBNL_01535 2.05e-58 - - - M - - - D-alanyl-D-alanine carboxypeptidase
NNAPIBNL_01536 1.64e-57 - - - S - - - Bacteriophage holin family
NNAPIBNL_01539 3.63e-99 - - - S - - - Domain of unknown function (DUF2479)
NNAPIBNL_01540 0.0 - - - M - - - Pectate lyase superfamily protein
NNAPIBNL_01541 4.15e-125 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NNAPIBNL_01543 0.0 - - - D - - - Phage tail tape measure protein
NNAPIBNL_01548 4.74e-43 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NNAPIBNL_01549 1.41e-26 - - - S - - - Phage head-tail joining protein
NNAPIBNL_01551 6.72e-130 - - - S - - - capsid protein
NNAPIBNL_01552 2.8e-68 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NNAPIBNL_01553 9.64e-183 - - - S - - - portal protein
NNAPIBNL_01555 9.42e-163 terL - - S - - - Terminase
NNAPIBNL_01556 4.47e-68 - - - L - - - Terminase, small subunit
NNAPIBNL_01561 6.63e-10 - - - L ko:K07451 - ko00000,ko01000,ko02048 COG1403 Restriction endonuclease
NNAPIBNL_01568 1.69e-65 - - - K - - - BRO family, N-terminal domain
NNAPIBNL_01574 2.58e-72 - - - L - - - Arm DNA-binding domain
NNAPIBNL_01576 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NNAPIBNL_01577 2.73e-248 yubA - - S - - - transporter activity
NNAPIBNL_01578 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NNAPIBNL_01579 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NNAPIBNL_01580 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNAPIBNL_01581 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNAPIBNL_01582 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNAPIBNL_01583 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNAPIBNL_01584 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NNAPIBNL_01585 1.82e-52 - - - - - - - -
NNAPIBNL_01586 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NNAPIBNL_01587 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNAPIBNL_01588 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNAPIBNL_01589 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NNAPIBNL_01590 3.56e-22 - - - - - - - -
NNAPIBNL_01591 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
NNAPIBNL_01592 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NNAPIBNL_01593 4.57e-90 yugN - - S - - - YugN-like family
NNAPIBNL_01595 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NNAPIBNL_01596 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NNAPIBNL_01597 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NNAPIBNL_01598 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NNAPIBNL_01599 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NNAPIBNL_01600 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NNAPIBNL_01601 1.53e-108 alaR - - K - - - Transcriptional regulator
NNAPIBNL_01602 3.41e-192 yugF - - I - - - Hydrolase
NNAPIBNL_01603 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
NNAPIBNL_01604 1.89e-276 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NNAPIBNL_01605 5e-278 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_01606 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NNAPIBNL_01607 2.44e-147 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NNAPIBNL_01608 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
NNAPIBNL_01609 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NNAPIBNL_01610 5.95e-92 yuxK - - S - - - protein conserved in bacteria
NNAPIBNL_01611 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
NNAPIBNL_01612 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NNAPIBNL_01613 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NNAPIBNL_01614 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NNAPIBNL_01615 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_01616 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNAPIBNL_01617 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNAPIBNL_01619 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NNAPIBNL_01620 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNAPIBNL_01621 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNAPIBNL_01622 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNAPIBNL_01623 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNAPIBNL_01624 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NNAPIBNL_01625 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NNAPIBNL_01626 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NNAPIBNL_01627 1.34e-146 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNAPIBNL_01628 1.19e-315 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_01630 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NNAPIBNL_01631 1.87e-11 - - - S - - - DegQ (SacQ) family
NNAPIBNL_01632 1.59e-62 yuzC - - - - - - -
NNAPIBNL_01633 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NNAPIBNL_01634 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNAPIBNL_01635 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NNAPIBNL_01636 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
NNAPIBNL_01637 1.1e-50 yueH - - S - - - YueH-like protein
NNAPIBNL_01638 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NNAPIBNL_01639 2.31e-232 yueF - - S - - - transporter activity
NNAPIBNL_01640 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
NNAPIBNL_01641 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NNAPIBNL_01642 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_01643 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
NNAPIBNL_01644 0.0 yueB - - S - - - type VII secretion protein EsaA
NNAPIBNL_01645 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NNAPIBNL_01646 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NNAPIBNL_01647 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NNAPIBNL_01648 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
NNAPIBNL_01649 1.66e-288 yukF - - QT - - - Transcriptional regulator
NNAPIBNL_01650 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NNAPIBNL_01651 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NNAPIBNL_01652 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NNAPIBNL_01653 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_01654 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NNAPIBNL_01655 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NNAPIBNL_01656 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NNAPIBNL_01657 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_01658 2.31e-198 eSD - - S ko:K07017 - ko00000 Putative esterase
NNAPIBNL_01659 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NNAPIBNL_01660 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NNAPIBNL_01661 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NNAPIBNL_01662 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NNAPIBNL_01663 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NNAPIBNL_01664 2.23e-149 yuiC - - S - - - protein conserved in bacteria
NNAPIBNL_01665 1.21e-45 yuiB - - S - - - Putative membrane protein
NNAPIBNL_01666 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNAPIBNL_01667 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NNAPIBNL_01669 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNAPIBNL_01670 1.57e-37 - - - - - - - -
NNAPIBNL_01671 1.09e-86 - - - CP - - - Membrane
NNAPIBNL_01672 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNAPIBNL_01674 1.12e-37 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
NNAPIBNL_01676 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NNAPIBNL_01677 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_01678 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NNAPIBNL_01679 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNAPIBNL_01680 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NNAPIBNL_01681 1.61e-48 yuzB - - S - - - Belongs to the UPF0349 family
NNAPIBNL_01682 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NNAPIBNL_01683 2.61e-70 yuzD - - S - - - protein conserved in bacteria
NNAPIBNL_01684 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NNAPIBNL_01685 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NNAPIBNL_01686 1.55e-70 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NNAPIBNL_01687 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNAPIBNL_01688 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NNAPIBNL_01689 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NNAPIBNL_01690 5.56e-244 yutH - - S - - - Spore coat protein
NNAPIBNL_01691 1.07e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NNAPIBNL_01692 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNAPIBNL_01693 3e-93 yutE - - S - - - Protein of unknown function DUF86
NNAPIBNL_01694 3.71e-62 yutD - - S - - - protein conserved in bacteria
NNAPIBNL_01695 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NNAPIBNL_01696 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NNAPIBNL_01697 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NNAPIBNL_01698 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NNAPIBNL_01699 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NNAPIBNL_01700 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
NNAPIBNL_01701 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
NNAPIBNL_01702 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NNAPIBNL_01703 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NNAPIBNL_01704 6.3e-86 - - - - - - - -
NNAPIBNL_01705 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_01706 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NNAPIBNL_01707 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NNAPIBNL_01708 3.33e-209 bsn - - L - - - Ribonuclease
NNAPIBNL_01709 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_01710 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NNAPIBNL_01711 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NNAPIBNL_01712 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NNAPIBNL_01713 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNAPIBNL_01714 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NNAPIBNL_01715 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NNAPIBNL_01716 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
NNAPIBNL_01718 1.34e-95 - - - - - - - -
NNAPIBNL_01719 1.96e-27 - - - S - - - Sporulation delaying protein SdpA
NNAPIBNL_01721 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NNAPIBNL_01722 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NNAPIBNL_01723 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
NNAPIBNL_01724 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
NNAPIBNL_01725 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NNAPIBNL_01726 2.79e-14 - - - - - - - -
NNAPIBNL_01727 3.22e-63 - - - - - - - -
NNAPIBNL_01729 5.17e-88 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_01730 7.85e-77 - - - S - - - Pfam:Phage_holin_4_1
NNAPIBNL_01733 1.12e-188 - - - S - - - Domain of unknown function (DUF2479)
NNAPIBNL_01734 4.63e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NNAPIBNL_01735 2.45e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNAPIBNL_01736 3.03e-183 ywqG - - S - - - Domain of unknown function (DUF1963)
NNAPIBNL_01738 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
NNAPIBNL_01739 2.69e-288 ywqJ - - S - - - Pre-toxin TG
NNAPIBNL_01740 2.19e-75 - - - S - - - SUKH-4 immunity protein
NNAPIBNL_01741 1.92e-25 - - - - - - - -
NNAPIBNL_01742 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
NNAPIBNL_01743 7.15e-83 - - - - - - - -
NNAPIBNL_01744 1.29e-130 - - - - - - - -
NNAPIBNL_01745 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NNAPIBNL_01746 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NNAPIBNL_01747 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NNAPIBNL_01748 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NNAPIBNL_01750 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NNAPIBNL_01751 3.88e-09 - - - - - - - -
NNAPIBNL_01752 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
NNAPIBNL_01753 4.38e-157 cotB - - - ko:K06325 - ko00000 -
NNAPIBNL_01754 8.96e-150 ywrJ - - - - - - -
NNAPIBNL_01755 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNAPIBNL_01756 5.73e-210 alsR - - K - - - LysR substrate binding domain
NNAPIBNL_01757 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NNAPIBNL_01758 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NNAPIBNL_01759 2.39e-115 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NNAPIBNL_01760 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
NNAPIBNL_01761 1.28e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NNAPIBNL_01762 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NNAPIBNL_01763 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NNAPIBNL_01764 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NNAPIBNL_01765 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNAPIBNL_01766 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NNAPIBNL_01767 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NNAPIBNL_01768 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NNAPIBNL_01769 6.95e-228 - - - E - - - Spore germination protein
NNAPIBNL_01770 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NNAPIBNL_01771 8.45e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NNAPIBNL_01772 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NNAPIBNL_01773 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NNAPIBNL_01774 1.16e-28 ywtC - - - - - - -
NNAPIBNL_01775 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NNAPIBNL_01776 1.4e-60 yttA - - S - - - Pfam Transposase IS66
NNAPIBNL_01777 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NNAPIBNL_01778 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
NNAPIBNL_01779 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNAPIBNL_01780 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
NNAPIBNL_01781 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NNAPIBNL_01782 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NNAPIBNL_01783 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NNAPIBNL_01784 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNAPIBNL_01785 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNAPIBNL_01786 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNAPIBNL_01787 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NNAPIBNL_01788 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NNAPIBNL_01789 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
NNAPIBNL_01790 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NNAPIBNL_01791 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NNAPIBNL_01792 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NNAPIBNL_01793 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNAPIBNL_01794 8.48e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNAPIBNL_01795 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NNAPIBNL_01796 1.99e-39 - - - - - - - -
NNAPIBNL_01797 0.0 lytB - - D - - - Stage II sporulation protein
NNAPIBNL_01798 4.43e-268 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_01799 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNAPIBNL_01800 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_01801 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NNAPIBNL_01802 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNAPIBNL_01803 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NNAPIBNL_01804 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NNAPIBNL_01805 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NNAPIBNL_01806 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NNAPIBNL_01807 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NNAPIBNL_01808 9.24e-234 yvhJ - - K - - - Transcriptional regulator
NNAPIBNL_01809 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NNAPIBNL_01810 2.31e-245 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NNAPIBNL_01811 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNAPIBNL_01812 3.16e-197 degV - - S - - - protein conserved in bacteria
NNAPIBNL_01813 5.41e-316 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NNAPIBNL_01814 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NNAPIBNL_01815 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NNAPIBNL_01816 6.15e-95 yvyF - - S - - - flagellar protein
NNAPIBNL_01817 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NNAPIBNL_01818 1.43e-101 yvyG - - NOU - - - FlgN protein
NNAPIBNL_01819 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NNAPIBNL_01820 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NNAPIBNL_01821 1.27e-104 yviE - - - - - - -
NNAPIBNL_01822 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NNAPIBNL_01823 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NNAPIBNL_01824 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NNAPIBNL_01825 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NNAPIBNL_01826 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NNAPIBNL_01827 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NNAPIBNL_01828 1.92e-89 - - - - - - - -
NNAPIBNL_01829 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNAPIBNL_01830 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNAPIBNL_01831 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNAPIBNL_01832 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_01833 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NNAPIBNL_01834 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NNAPIBNL_01835 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NNAPIBNL_01836 1.35e-271 ywoF - - P - - - Right handed beta helix region
NNAPIBNL_01837 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NNAPIBNL_01838 5.83e-72 swrA - - S - - - Swarming motility protein
NNAPIBNL_01839 1.39e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NNAPIBNL_01842 3.49e-290 yvkA - - P - - - -transporter
NNAPIBNL_01843 1.12e-119 yvkB - - K - - - Transcriptional regulator
NNAPIBNL_01844 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NNAPIBNL_01845 2.59e-45 csbA - - S - - - protein conserved in bacteria
NNAPIBNL_01846 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNAPIBNL_01847 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNAPIBNL_01848 1.29e-40 yvkN - - - - - - -
NNAPIBNL_01849 1.79e-61 yvlA - - - - - - -
NNAPIBNL_01850 4.14e-214 yvlB - - S - - - Putative adhesin
NNAPIBNL_01851 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NNAPIBNL_01852 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
NNAPIBNL_01853 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NNAPIBNL_01854 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NNAPIBNL_01855 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NNAPIBNL_01856 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNAPIBNL_01857 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NNAPIBNL_01858 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNAPIBNL_01859 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNAPIBNL_01860 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NNAPIBNL_01861 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NNAPIBNL_01862 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
NNAPIBNL_01863 8.64e-258 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NNAPIBNL_01864 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NNAPIBNL_01865 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NNAPIBNL_01866 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NNAPIBNL_01867 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NNAPIBNL_01868 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NNAPIBNL_01869 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NNAPIBNL_01870 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NNAPIBNL_01871 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NNAPIBNL_01872 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_01873 1.01e-231 sasA - - T - - - Histidine kinase
NNAPIBNL_01874 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NNAPIBNL_01875 7.8e-192 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NNAPIBNL_01876 6.06e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNAPIBNL_01877 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NNAPIBNL_01878 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NNAPIBNL_01879 3.01e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NNAPIBNL_01880 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NNAPIBNL_01881 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NNAPIBNL_01882 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NNAPIBNL_01883 4.11e-100 - - - M - - - Ribonuclease
NNAPIBNL_01884 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNAPIBNL_01885 1.42e-133 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NNAPIBNL_01886 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NNAPIBNL_01887 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NNAPIBNL_01888 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NNAPIBNL_01889 1.06e-110 - - - - - - - -
NNAPIBNL_01890 6.64e-313 - - - EGP - - - Sugar (and other) transporter
NNAPIBNL_01891 3.16e-258 yraM - - S - - - PrpF protein
NNAPIBNL_01892 1.4e-202 yraN - - K - - - Transcriptional regulator
NNAPIBNL_01893 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNAPIBNL_01894 2.68e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NNAPIBNL_01895 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NNAPIBNL_01896 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNAPIBNL_01898 3.08e-44 - - - - - - - -
NNAPIBNL_01899 0.0 - - - I - - - Pfam Lipase (class 3)
NNAPIBNL_01900 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
NNAPIBNL_01901 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
NNAPIBNL_01902 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
NNAPIBNL_01903 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
NNAPIBNL_01904 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NNAPIBNL_01905 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNAPIBNL_01906 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
NNAPIBNL_01907 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
NNAPIBNL_01908 4.2e-164 - - - CH - - - FAD binding domain
NNAPIBNL_01909 8.3e-111 ywjB - - H - - - RibD C-terminal domain
NNAPIBNL_01911 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NNAPIBNL_01912 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NNAPIBNL_01913 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NNAPIBNL_01914 4.44e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NNAPIBNL_01915 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NNAPIBNL_01916 3.48e-268 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NNAPIBNL_01917 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNAPIBNL_01918 1.95e-253 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NNAPIBNL_01919 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NNAPIBNL_01920 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NNAPIBNL_01921 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NNAPIBNL_01922 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NNAPIBNL_01923 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_01924 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NNAPIBNL_01925 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NNAPIBNL_01926 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NNAPIBNL_01927 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NNAPIBNL_01928 4.01e-44 yvfG - - S - - - YvfG protein
NNAPIBNL_01929 1.33e-292 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NNAPIBNL_01930 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NNAPIBNL_01931 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NNAPIBNL_01932 2.07e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNAPIBNL_01933 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNAPIBNL_01934 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NNAPIBNL_01935 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NNAPIBNL_01936 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NNAPIBNL_01937 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NNAPIBNL_01938 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
NNAPIBNL_01940 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_01941 5.35e-196 yvbV - - EG - - - EamA-like transporter family
NNAPIBNL_01942 2.18e-124 yvbU - - K - - - Transcriptional regulator
NNAPIBNL_01943 3.86e-18 yvbU - - K - - - Transcriptional regulator
NNAPIBNL_01944 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_01945 1.76e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NNAPIBNL_01946 4.6e-272 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNAPIBNL_01948 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NNAPIBNL_01949 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNAPIBNL_01950 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NNAPIBNL_01951 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNAPIBNL_01952 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NNAPIBNL_01953 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNAPIBNL_01954 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NNAPIBNL_01955 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NNAPIBNL_01956 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NNAPIBNL_01957 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
NNAPIBNL_01958 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NNAPIBNL_01959 2.49e-179 - - - M - - - Protein involved in cellulose biosynthesis
NNAPIBNL_01960 1.13e-182 - - - C - - - WbqC-like protein family
NNAPIBNL_01961 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
NNAPIBNL_01962 1.87e-219 - - - - - - - -
NNAPIBNL_01963 4.16e-260 - - - EGP - - - Major facilitator Superfamily
NNAPIBNL_01964 5.07e-103 yvbK - - K - - - acetyltransferase
NNAPIBNL_01965 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NNAPIBNL_01966 2.61e-148 yvbI - - M - - - Membrane
NNAPIBNL_01967 1.55e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NNAPIBNL_01968 2.67e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NNAPIBNL_01969 1.21e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNAPIBNL_01970 5.4e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNAPIBNL_01971 2.99e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNAPIBNL_01972 2.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNAPIBNL_01973 3.5e-108 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NNAPIBNL_01974 1.25e-262 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NNAPIBNL_01975 7.36e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNAPIBNL_01976 5.17e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NNAPIBNL_01977 1.41e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NNAPIBNL_01978 1.27e-160 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_01979 1.91e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNAPIBNL_01980 4.95e-170 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NNAPIBNL_01981 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NNAPIBNL_01982 3.51e-308 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NNAPIBNL_01983 1.17e-67 yvaP - - K - - - transcriptional
NNAPIBNL_01984 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NNAPIBNL_01985 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NNAPIBNL_01986 1.64e-47 yvzC - - K - - - transcriptional
NNAPIBNL_01987 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NNAPIBNL_01988 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NNAPIBNL_01989 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNAPIBNL_01990 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NNAPIBNL_01992 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NNAPIBNL_01993 1.18e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_01994 4.27e-201 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NNAPIBNL_01995 5.25e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNAPIBNL_01996 3.28e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NNAPIBNL_01997 1.8e-181 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NNAPIBNL_01998 1.35e-152 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNAPIBNL_01999 5.33e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNAPIBNL_02000 3.93e-175 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNAPIBNL_02001 1.43e-225 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_02002 1.97e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NNAPIBNL_02003 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_02004 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NNAPIBNL_02005 4.69e-238 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NNAPIBNL_02006 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NNAPIBNL_02007 9.29e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
NNAPIBNL_02008 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NNAPIBNL_02009 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NNAPIBNL_02010 2.51e-135 bdbD - - O - - - Thioredoxin
NNAPIBNL_02011 5.06e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NNAPIBNL_02012 5.24e-188 - - - S - - - Metallo-peptidase family M12
NNAPIBNL_02013 6.1e-128 yvgT - - S - - - membrane
NNAPIBNL_02015 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNAPIBNL_02016 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NNAPIBNL_02017 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NNAPIBNL_02018 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NNAPIBNL_02019 1.55e-110 yvgO - - - - - - -
NNAPIBNL_02020 1.77e-200 yvgN - - S - - - reductase
NNAPIBNL_02021 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NNAPIBNL_02022 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NNAPIBNL_02023 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NNAPIBNL_02024 3.01e-237 - - - T - - - Histidine kinase
NNAPIBNL_02025 4.14e-146 yfiK - - K - - - Regulator
NNAPIBNL_02026 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NNAPIBNL_02027 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NNAPIBNL_02028 1.86e-62 - - - K - - - Virulence activator alpha C-term
NNAPIBNL_02029 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
NNAPIBNL_02030 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NNAPIBNL_02031 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NNAPIBNL_02032 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NNAPIBNL_02033 1.31e-114 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NNAPIBNL_02034 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_02035 4.33e-301 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_02036 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
NNAPIBNL_02037 6.43e-211 yccK - - C - - - Aldo keto reductase
NNAPIBNL_02038 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
NNAPIBNL_02039 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NNAPIBNL_02040 1.19e-58 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NNAPIBNL_02041 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NNAPIBNL_02042 1.47e-305 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NNAPIBNL_02043 3.41e-241 ycbU - - E - - - Selenocysteine lyase
NNAPIBNL_02044 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NNAPIBNL_02045 1.44e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NNAPIBNL_02046 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NNAPIBNL_02047 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NNAPIBNL_02048 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NNAPIBNL_02049 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
NNAPIBNL_02050 2.08e-15 - - - L - - - COG3666 Transposase and inactivated derivatives
NNAPIBNL_02051 3.11e-73 ydfQ - - CO - - - Thioredoxin
NNAPIBNL_02052 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
NNAPIBNL_02053 5.44e-229 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NNAPIBNL_02054 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NNAPIBNL_02055 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNAPIBNL_02056 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NNAPIBNL_02057 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NNAPIBNL_02058 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NNAPIBNL_02059 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_02060 4.31e-44 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NNAPIBNL_02061 7.21e-90 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NNAPIBNL_02062 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NNAPIBNL_02063 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NNAPIBNL_02064 7.12e-303 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNAPIBNL_02065 5.77e-246 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNAPIBNL_02066 2.61e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNAPIBNL_02067 4.36e-240 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NNAPIBNL_02068 9.76e-52 ybfN - - - - - - -
NNAPIBNL_02069 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NNAPIBNL_02070 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
NNAPIBNL_02071 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNAPIBNL_02072 6.7e-264 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNAPIBNL_02073 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NNAPIBNL_02074 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
NNAPIBNL_02076 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NNAPIBNL_02077 1e-23 - - - S - - - Protein of unknown function (DUF2651)
NNAPIBNL_02078 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NNAPIBNL_02079 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NNAPIBNL_02080 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
NNAPIBNL_02081 0.0 ybeC - - E - - - amino acid
NNAPIBNL_02082 2.17e-52 ybyB - - - - - - -
NNAPIBNL_02083 2.99e-136 yqeB - - - - - - -
NNAPIBNL_02084 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NNAPIBNL_02085 1.31e-99 - - - S - - - Domain of unknown function (DUF4879)
NNAPIBNL_02086 6.5e-33 - - - - - - - -
NNAPIBNL_02087 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NNAPIBNL_02088 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NNAPIBNL_02089 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NNAPIBNL_02090 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NNAPIBNL_02091 6.05e-227 - - - T - - - COG4585 Signal transduction histidine kinase
NNAPIBNL_02092 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NNAPIBNL_02093 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_02094 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_02095 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NNAPIBNL_02096 3.49e-134 yxaC - - M - - - effector of murein hydrolase
NNAPIBNL_02097 2.34e-203 dkgB - - S - - - Aldo/keto reductase family
NNAPIBNL_02098 9.57e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
NNAPIBNL_02099 3.07e-124 ybdN - - - - - - -
NNAPIBNL_02100 5.91e-68 - - - S - - - ABC-2 family transporter protein
NNAPIBNL_02101 2.6e-220 - - - O - - - growth
NNAPIBNL_02102 1.17e-21 - - - S - - - peptidyl-tyrosine sulfation
NNAPIBNL_02103 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNAPIBNL_02104 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNAPIBNL_02105 1.1e-291 ybbR - - S - - - protein conserved in bacteria
NNAPIBNL_02106 3.01e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNAPIBNL_02107 1.99e-145 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NNAPIBNL_02108 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_02114 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
NNAPIBNL_02115 1.13e-76 ybbJ - - J - - - acetyltransferase
NNAPIBNL_02116 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NNAPIBNL_02117 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02118 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NNAPIBNL_02119 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NNAPIBNL_02120 4.44e-291 ybbC - - S - - - protein conserved in bacteria
NNAPIBNL_02121 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NNAPIBNL_02122 1.12e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NNAPIBNL_02123 1.48e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02124 9.92e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02125 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
NNAPIBNL_02126 1.35e-216 ybaS - - S - - - Na -dependent transporter
NNAPIBNL_02127 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NNAPIBNL_02128 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NNAPIBNL_02129 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
NNAPIBNL_02130 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNAPIBNL_02131 2.1e-270 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NNAPIBNL_02132 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NNAPIBNL_02133 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NNAPIBNL_02134 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NNAPIBNL_02135 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NNAPIBNL_02136 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNAPIBNL_02137 1.22e-247 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NNAPIBNL_02138 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NNAPIBNL_02139 1.61e-156 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NNAPIBNL_02140 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NNAPIBNL_02141 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNAPIBNL_02142 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NNAPIBNL_02143 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NNAPIBNL_02144 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNAPIBNL_02145 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNAPIBNL_02146 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NNAPIBNL_02147 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NNAPIBNL_02148 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNAPIBNL_02149 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NNAPIBNL_02150 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNAPIBNL_02151 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNAPIBNL_02152 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNAPIBNL_02153 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNAPIBNL_02154 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NNAPIBNL_02155 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNAPIBNL_02156 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNAPIBNL_02157 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NNAPIBNL_02158 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNAPIBNL_02159 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNAPIBNL_02160 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNAPIBNL_02161 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNAPIBNL_02162 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
NNAPIBNL_02163 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NNAPIBNL_02164 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNAPIBNL_02165 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NNAPIBNL_02166 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNAPIBNL_02167 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNAPIBNL_02168 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNAPIBNL_02169 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNAPIBNL_02170 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNAPIBNL_02171 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNAPIBNL_02172 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NNAPIBNL_02173 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNAPIBNL_02174 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNAPIBNL_02175 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNAPIBNL_02176 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNAPIBNL_02177 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNAPIBNL_02178 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNAPIBNL_02179 1.75e-118 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNAPIBNL_02180 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNAPIBNL_02181 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNAPIBNL_02182 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NNAPIBNL_02183 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NNAPIBNL_02184 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNAPIBNL_02185 2.94e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNAPIBNL_02186 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NNAPIBNL_02187 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNAPIBNL_02188 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NNAPIBNL_02189 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNAPIBNL_02190 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNAPIBNL_02191 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNAPIBNL_02192 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NNAPIBNL_02193 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNAPIBNL_02194 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNAPIBNL_02195 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNAPIBNL_02196 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNAPIBNL_02197 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNAPIBNL_02198 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NNAPIBNL_02199 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
NNAPIBNL_02201 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
NNAPIBNL_02202 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_02203 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NNAPIBNL_02204 1.95e-102 gerD - - - ko:K06294 - ko00000 -
NNAPIBNL_02205 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NNAPIBNL_02206 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
NNAPIBNL_02207 1.46e-85 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_02208 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NNAPIBNL_02209 0.0 yvrG - - T - - - Histidine kinase
NNAPIBNL_02210 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_02211 1.14e-48 - - - - - - - -
NNAPIBNL_02212 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NNAPIBNL_02213 1.88e-21 - - - S - - - YvrJ protein family
NNAPIBNL_02214 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NNAPIBNL_02215 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
NNAPIBNL_02216 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NNAPIBNL_02217 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02218 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02219 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNAPIBNL_02220 2.77e-100 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NNAPIBNL_02221 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NNAPIBNL_02222 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NNAPIBNL_02223 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NNAPIBNL_02224 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NNAPIBNL_02225 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NNAPIBNL_02226 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NNAPIBNL_02227 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NNAPIBNL_02228 2.42e-61 - - - S - - - GlpM protein
NNAPIBNL_02229 1.64e-120 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NNAPIBNL_02230 4.49e-63 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NNAPIBNL_02231 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NNAPIBNL_02232 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNAPIBNL_02233 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNAPIBNL_02234 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNAPIBNL_02235 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNAPIBNL_02236 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNAPIBNL_02237 1.36e-36 yqzJ - - - - - - -
NNAPIBNL_02238 7.65e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNAPIBNL_02239 4.14e-256 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NNAPIBNL_02240 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNAPIBNL_02241 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NNAPIBNL_02243 3.99e-118 yqjB - - S - - - protein conserved in bacteria
NNAPIBNL_02244 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NNAPIBNL_02245 1.13e-160 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNAPIBNL_02246 7.04e-140 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNAPIBNL_02247 2.18e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNAPIBNL_02248 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
NNAPIBNL_02249 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNAPIBNL_02250 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNAPIBNL_02251 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNAPIBNL_02252 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNAPIBNL_02253 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNAPIBNL_02254 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NNAPIBNL_02255 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNAPIBNL_02256 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NNAPIBNL_02257 0.0 bkdR - - KT - - - Transcriptional regulator
NNAPIBNL_02258 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NNAPIBNL_02259 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NNAPIBNL_02260 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NNAPIBNL_02261 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNAPIBNL_02262 9.37e-256 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NNAPIBNL_02263 8.59e-59 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NNAPIBNL_02264 1.22e-101 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NNAPIBNL_02265 1.21e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NNAPIBNL_02266 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NNAPIBNL_02267 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NNAPIBNL_02269 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
NNAPIBNL_02270 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
NNAPIBNL_02272 2.85e-266 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NNAPIBNL_02275 4.31e-260 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNAPIBNL_02277 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NNAPIBNL_02278 9.07e-297 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NNAPIBNL_02279 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NNAPIBNL_02280 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NNAPIBNL_02281 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NNAPIBNL_02282 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNAPIBNL_02283 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNAPIBNL_02284 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNAPIBNL_02285 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNAPIBNL_02286 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNAPIBNL_02287 2.12e-84 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNAPIBNL_02288 5.53e-87 yqhY - - S - - - protein conserved in bacteria
NNAPIBNL_02289 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NNAPIBNL_02290 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NNAPIBNL_02291 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NNAPIBNL_02292 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NNAPIBNL_02293 1.74e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NNAPIBNL_02294 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NNAPIBNL_02295 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NNAPIBNL_02296 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NNAPIBNL_02297 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NNAPIBNL_02298 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NNAPIBNL_02299 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
NNAPIBNL_02300 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNAPIBNL_02301 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NNAPIBNL_02302 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
NNAPIBNL_02303 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
NNAPIBNL_02304 8.59e-80 yqhP - - - - - - -
NNAPIBNL_02305 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NNAPIBNL_02306 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NNAPIBNL_02307 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NNAPIBNL_02308 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NNAPIBNL_02309 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNAPIBNL_02310 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NNAPIBNL_02311 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NNAPIBNL_02312 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NNAPIBNL_02313 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
NNAPIBNL_02314 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NNAPIBNL_02315 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NNAPIBNL_02316 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NNAPIBNL_02317 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NNAPIBNL_02318 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
NNAPIBNL_02319 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
NNAPIBNL_02320 9.56e-35 yqzE - - S - - - YqzE-like protein
NNAPIBNL_02321 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NNAPIBNL_02322 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NNAPIBNL_02323 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NNAPIBNL_02324 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
NNAPIBNL_02325 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NNAPIBNL_02326 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NNAPIBNL_02327 3e-116 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NNAPIBNL_02328 2.3e-57 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NNAPIBNL_02329 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
NNAPIBNL_02331 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNAPIBNL_02332 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NNAPIBNL_02333 4.8e-141 yneB - - L - - - resolvase
NNAPIBNL_02334 2.33e-43 ynzC - - S - - - UPF0291 protein
NNAPIBNL_02335 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NNAPIBNL_02336 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NNAPIBNL_02337 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NNAPIBNL_02338 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
NNAPIBNL_02339 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NNAPIBNL_02340 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NNAPIBNL_02341 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NNAPIBNL_02342 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
NNAPIBNL_02343 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
NNAPIBNL_02344 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NNAPIBNL_02345 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NNAPIBNL_02346 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NNAPIBNL_02347 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NNAPIBNL_02349 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NNAPIBNL_02350 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NNAPIBNL_02351 5.95e-65 yneQ - - - - - - -
NNAPIBNL_02352 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
NNAPIBNL_02353 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNAPIBNL_02354 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NNAPIBNL_02355 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNAPIBNL_02356 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNAPIBNL_02357 2.21e-19 - - - - - - - -
NNAPIBNL_02358 2.04e-60 ynfC - - - - - - -
NNAPIBNL_02359 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NNAPIBNL_02360 1.56e-28 yndG - - S - - - DoxX-like family
NNAPIBNL_02361 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
NNAPIBNL_02362 0.0 yndJ - - S - - - YndJ-like protein
NNAPIBNL_02363 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
NNAPIBNL_02364 3.49e-282 - - - T - - - Histidine kinase
NNAPIBNL_02365 7.49e-155 - - - T - - - Transcriptional regulatory protein, C terminal
NNAPIBNL_02366 4.05e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NNAPIBNL_02367 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NNAPIBNL_02368 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_02369 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_02370 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_02371 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NNAPIBNL_02372 9.33e-177 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NNAPIBNL_02373 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NNAPIBNL_02374 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NNAPIBNL_02375 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NNAPIBNL_02376 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NNAPIBNL_02377 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NNAPIBNL_02378 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NNAPIBNL_02379 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNAPIBNL_02380 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NNAPIBNL_02382 2.47e-166 yphF - - - - - - -
NNAPIBNL_02383 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
NNAPIBNL_02384 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NNAPIBNL_02385 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NNAPIBNL_02386 6.38e-129 yphA - - - - - - -
NNAPIBNL_02387 1.32e-12 - - - S - - - YpzI-like protein
NNAPIBNL_02388 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNAPIBNL_02389 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NNAPIBNL_02390 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NNAPIBNL_02391 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
NNAPIBNL_02392 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
NNAPIBNL_02393 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
NNAPIBNL_02394 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NNAPIBNL_02395 5.23e-131 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NNAPIBNL_02396 9.8e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NNAPIBNL_02397 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NNAPIBNL_02398 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
NNAPIBNL_02399 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
NNAPIBNL_02401 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NNAPIBNL_02402 7.8e-78 gtcA - - S - - - GtrA-like protein
NNAPIBNL_02403 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNAPIBNL_02404 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NNAPIBNL_02405 5.74e-48 ydaS - - S - - - membrane
NNAPIBNL_02406 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NNAPIBNL_02407 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNAPIBNL_02408 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NNAPIBNL_02409 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NNAPIBNL_02410 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NNAPIBNL_02411 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NNAPIBNL_02412 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NNAPIBNL_02413 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NNAPIBNL_02414 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
NNAPIBNL_02415 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
NNAPIBNL_02416 4.96e-161 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_02417 1.26e-150 - - - K - - - WYL domain
NNAPIBNL_02418 1.83e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_02419 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNAPIBNL_02421 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NNAPIBNL_02422 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02423 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NNAPIBNL_02424 6.09e-27 ywdA - - - - - - -
NNAPIBNL_02425 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NNAPIBNL_02427 3.8e-184 ywdF - - S - - - Glycosyltransferase like family 2
NNAPIBNL_02428 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNAPIBNL_02429 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
NNAPIBNL_02430 3.47e-287 ywdJ - - F - - - Xanthine uracil
NNAPIBNL_02431 4.39e-76 ywdK - - S - - - small membrane protein
NNAPIBNL_02432 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NNAPIBNL_02433 4.13e-180 spsA - - M - - - Spore Coat
NNAPIBNL_02434 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NNAPIBNL_02435 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NNAPIBNL_02436 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NNAPIBNL_02437 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NNAPIBNL_02438 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
NNAPIBNL_02439 3.01e-212 spsG - - M - - - Spore Coat
NNAPIBNL_02440 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNAPIBNL_02441 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNAPIBNL_02442 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNAPIBNL_02443 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NNAPIBNL_02444 4.02e-80 - - - - - - - -
NNAPIBNL_02445 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNAPIBNL_02446 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNAPIBNL_02447 0.0 rocB - - E - - - arginine degradation protein
NNAPIBNL_02448 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NNAPIBNL_02449 4.86e-249 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NNAPIBNL_02450 8.02e-277 ywfA - - EGP - - - -transporter
NNAPIBNL_02451 1.16e-107 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NNAPIBNL_02452 1.63e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NNAPIBNL_02453 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_02454 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NNAPIBNL_02455 2.33e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NNAPIBNL_02456 5.35e-289 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NNAPIBNL_02457 6.08e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NNAPIBNL_02459 2.37e-20 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NNAPIBNL_02460 6.64e-185 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NNAPIBNL_02461 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NNAPIBNL_02462 9.29e-207 - - - S - - - Conserved hypothetical protein 698
NNAPIBNL_02463 1.33e-199 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_02464 8.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NNAPIBNL_02466 4.4e-208 - - - - - - - -
NNAPIBNL_02468 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NNAPIBNL_02469 1.37e-26 ykzE - - - - - - -
NNAPIBNL_02470 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
NNAPIBNL_02471 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NNAPIBNL_02472 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NNAPIBNL_02473 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
NNAPIBNL_02474 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NNAPIBNL_02475 3.51e-221 ykrI - - S - - - Anti-sigma factor N-terminus
NNAPIBNL_02476 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_02477 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NNAPIBNL_02478 1.21e-123 ykoX - - S - - - membrane-associated protein
NNAPIBNL_02479 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NNAPIBNL_02480 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NNAPIBNL_02481 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NNAPIBNL_02482 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
NNAPIBNL_02483 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NNAPIBNL_02484 3.57e-35 ykoL - - - - - - -
NNAPIBNL_02485 2.24e-23 - - - - - - - -
NNAPIBNL_02486 3.53e-69 tnrA - - K - - - transcriptional
NNAPIBNL_02487 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NNAPIBNL_02489 4.54e-303 ydhD - - M - - - Glycosyl hydrolase
NNAPIBNL_02490 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NNAPIBNL_02491 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_02492 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NNAPIBNL_02493 2.08e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNAPIBNL_02494 3.07e-16 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNAPIBNL_02495 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNAPIBNL_02496 3.96e-107 - - - T - - - universal stress protein
NNAPIBNL_02497 1.17e-118 ymcC - - S - - - Membrane
NNAPIBNL_02498 9.13e-126 pksA - - K - - - Transcriptional regulator
NNAPIBNL_02499 1.05e-191 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NNAPIBNL_02500 6.85e-192 nodB1 - - G - - - deacetylase
NNAPIBNL_02501 3.53e-172 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NNAPIBNL_02502 5.39e-252 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NNAPIBNL_02503 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
NNAPIBNL_02504 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NNAPIBNL_02505 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNAPIBNL_02506 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNAPIBNL_02507 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NNAPIBNL_02508 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NNAPIBNL_02509 9.37e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NNAPIBNL_02510 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NNAPIBNL_02511 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNAPIBNL_02512 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NNAPIBNL_02513 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_02514 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
NNAPIBNL_02515 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
NNAPIBNL_02516 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NNAPIBNL_02517 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
NNAPIBNL_02518 3.42e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_02519 2.19e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNAPIBNL_02520 1.7e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_02521 2.28e-166 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNAPIBNL_02522 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NNAPIBNL_02523 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NNAPIBNL_02524 5.72e-314 ygxB - - M - - - Conserved TM helix
NNAPIBNL_02525 1.49e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NNAPIBNL_02526 1.69e-282 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NNAPIBNL_02527 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
NNAPIBNL_02528 1.16e-51 yhdB - - S - - - YhdB-like protein
NNAPIBNL_02529 2.89e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NNAPIBNL_02530 5.61e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NNAPIBNL_02531 2.73e-247 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_02532 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NNAPIBNL_02533 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NNAPIBNL_02534 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNAPIBNL_02535 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NNAPIBNL_02536 2.26e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NNAPIBNL_02537 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNAPIBNL_02538 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNAPIBNL_02539 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
NNAPIBNL_02540 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
NNAPIBNL_02541 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
NNAPIBNL_02542 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NNAPIBNL_02543 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NNAPIBNL_02544 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NNAPIBNL_02545 2.2e-149 yhcQ - - M - - - Spore coat protein
NNAPIBNL_02546 3.99e-199 yhcP - - - - - - -
NNAPIBNL_02547 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNAPIBNL_02548 5.08e-60 yhcM - - - - - - -
NNAPIBNL_02549 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NNAPIBNL_02550 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNAPIBNL_02551 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NNAPIBNL_02552 6.9e-161 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NNAPIBNL_02553 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NNAPIBNL_02554 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NNAPIBNL_02555 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_02556 8.89e-147 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_02557 3.06e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_02558 7.54e-65 - - - - - - - -
NNAPIBNL_02559 1.03e-65 yhcC - - - - - - -
NNAPIBNL_02560 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NNAPIBNL_02561 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NNAPIBNL_02562 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NNAPIBNL_02563 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NNAPIBNL_02564 1.74e-275 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NNAPIBNL_02565 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NNAPIBNL_02566 4.51e-08 - - - - - - - -
NNAPIBNL_02567 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NNAPIBNL_02568 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NNAPIBNL_02569 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
NNAPIBNL_02570 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNAPIBNL_02571 8.37e-216 yhbB - - S - - - Putative amidase domain
NNAPIBNL_02572 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NNAPIBNL_02573 1.34e-138 yhzB - - S - - - B3/4 domain
NNAPIBNL_02575 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_02576 2.4e-102 ygaO - - - - - - -
NNAPIBNL_02577 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNAPIBNL_02579 5.74e-266 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NNAPIBNL_02580 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NNAPIBNL_02581 5.5e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NNAPIBNL_02582 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NNAPIBNL_02583 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
NNAPIBNL_02584 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNAPIBNL_02585 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_02586 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NNAPIBNL_02587 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NNAPIBNL_02588 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNAPIBNL_02589 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
NNAPIBNL_02591 3.15e-313 ygaK - - C - - - Berberine and berberine like
NNAPIBNL_02592 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NNAPIBNL_02593 2.28e-156 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NNAPIBNL_02594 2.25e-311 - - - C - - - Na+/H+ antiporter family
NNAPIBNL_02596 4.25e-126 - - - K - - - Helix-turn-helix domain
NNAPIBNL_02600 1.04e-45 - - - S - - - Bacteriophage A118-like holin, Hol118
NNAPIBNL_02601 7.04e-186 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NNAPIBNL_02602 1.66e-39 - - - S - - - BhlA holin family
NNAPIBNL_02605 2.47e-104 - - - - - - - -
NNAPIBNL_02606 6.24e-90 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NNAPIBNL_02607 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NNAPIBNL_02608 6.72e-37 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNAPIBNL_02609 7.18e-140 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNAPIBNL_02610 2.06e-313 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NNAPIBNL_02611 1.26e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NNAPIBNL_02612 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NNAPIBNL_02613 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NNAPIBNL_02614 1.05e-227 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNAPIBNL_02615 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NNAPIBNL_02616 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNAPIBNL_02617 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNAPIBNL_02618 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02619 1.35e-58 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02620 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NNAPIBNL_02621 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NNAPIBNL_02622 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NNAPIBNL_02623 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02624 6.1e-216 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNAPIBNL_02625 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NNAPIBNL_02626 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NNAPIBNL_02627 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NNAPIBNL_02628 4.85e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNAPIBNL_02629 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02630 2.82e-315 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NNAPIBNL_02631 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NNAPIBNL_02632 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNAPIBNL_02633 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_02634 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NNAPIBNL_02635 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_02636 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NNAPIBNL_02637 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NNAPIBNL_02638 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NNAPIBNL_02640 2.87e-205 gspA - - M - - - General stress
NNAPIBNL_02641 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNAPIBNL_02642 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNAPIBNL_02643 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NNAPIBNL_02644 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NNAPIBNL_02645 1.97e-200 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NNAPIBNL_02646 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NNAPIBNL_02647 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NNAPIBNL_02648 6.2e-142 ywbG - - M - - - effector of murein hydrolase
NNAPIBNL_02649 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NNAPIBNL_02650 2.29e-200 ywbI - - K - - - Transcriptional regulator
NNAPIBNL_02651 9.98e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NNAPIBNL_02652 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NNAPIBNL_02653 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NNAPIBNL_02654 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NNAPIBNL_02655 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NNAPIBNL_02656 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NNAPIBNL_02657 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNAPIBNL_02658 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NNAPIBNL_02659 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NNAPIBNL_02660 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNAPIBNL_02661 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
NNAPIBNL_02662 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNAPIBNL_02663 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNAPIBNL_02665 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NNAPIBNL_02666 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNAPIBNL_02667 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NNAPIBNL_02668 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NNAPIBNL_02669 3.81e-142 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NNAPIBNL_02670 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NNAPIBNL_02671 7.86e-68 ypuD - - - - - - -
NNAPIBNL_02672 8.88e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNAPIBNL_02673 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
NNAPIBNL_02674 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNAPIBNL_02675 3.35e-194 ypuA - - S - - - Secreted protein
NNAPIBNL_02676 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNAPIBNL_02677 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NNAPIBNL_02678 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
NNAPIBNL_02679 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NNAPIBNL_02680 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NNAPIBNL_02681 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NNAPIBNL_02682 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NNAPIBNL_02683 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_02684 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NNAPIBNL_02685 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NNAPIBNL_02686 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNAPIBNL_02687 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NNAPIBNL_02688 4.39e-288 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNAPIBNL_02689 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NNAPIBNL_02690 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NNAPIBNL_02691 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NNAPIBNL_02692 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NNAPIBNL_02693 2.87e-43 yqkK - - - - - - -
NNAPIBNL_02694 5.05e-33 - - - - - - - -
NNAPIBNL_02695 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NNAPIBNL_02696 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NNAPIBNL_02697 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NNAPIBNL_02698 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NNAPIBNL_02699 2.32e-75 ansR - - K - - - Transcriptional regulator
NNAPIBNL_02700 1.43e-271 yqxK - - L - - - DNA helicase
NNAPIBNL_02701 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NNAPIBNL_02702 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
NNAPIBNL_02703 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NNAPIBNL_02704 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
NNAPIBNL_02705 2.33e-170 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NNAPIBNL_02706 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
NNAPIBNL_02707 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
NNAPIBNL_02708 1.93e-212 yqkA - - K - - - GrpB protein
NNAPIBNL_02709 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NNAPIBNL_02710 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NNAPIBNL_02711 1.01e-293 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNAPIBNL_02712 7.27e-73 - - - S - - - YolD-like protein
NNAPIBNL_02714 7.76e-204 yueF - - S - - - transporter activity
NNAPIBNL_02716 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NNAPIBNL_02717 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NNAPIBNL_02718 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_02719 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNAPIBNL_02720 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNAPIBNL_02721 5.87e-84 - - - K - - - LysR substrate binding domain
NNAPIBNL_02722 5.76e-241 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NNAPIBNL_02723 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NNAPIBNL_02724 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NNAPIBNL_02725 1.61e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NNAPIBNL_02726 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NNAPIBNL_02727 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NNAPIBNL_02728 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NNAPIBNL_02729 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NNAPIBNL_02730 8.01e-77 ylbA - - S - - - YugN-like family
NNAPIBNL_02731 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
NNAPIBNL_02732 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
NNAPIBNL_02733 5.5e-83 ylbD - - S - - - Putative coat protein
NNAPIBNL_02734 1.73e-48 ylbE - - S - - - YlbE-like protein
NNAPIBNL_02735 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
NNAPIBNL_02736 4.62e-56 ylbG - - S - - - UPF0298 protein
NNAPIBNL_02737 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NNAPIBNL_02738 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNAPIBNL_02739 5.5e-266 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NNAPIBNL_02740 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NNAPIBNL_02741 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NNAPIBNL_02742 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
NNAPIBNL_02743 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NNAPIBNL_02744 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NNAPIBNL_02745 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NNAPIBNL_02746 2.68e-115 ylbP - - K - - - n-acetyltransferase
NNAPIBNL_02747 2.11e-188 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNAPIBNL_02748 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NNAPIBNL_02749 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NNAPIBNL_02750 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNAPIBNL_02751 2.81e-67 ftsL - - D - - - Essential cell division protein
NNAPIBNL_02752 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNAPIBNL_02753 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NNAPIBNL_02754 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNAPIBNL_02755 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNAPIBNL_02756 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNAPIBNL_02757 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNAPIBNL_02758 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNAPIBNL_02759 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NNAPIBNL_02760 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNAPIBNL_02761 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNAPIBNL_02762 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNAPIBNL_02763 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NNAPIBNL_02764 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NNAPIBNL_02765 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_02766 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_02767 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NNAPIBNL_02768 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NNAPIBNL_02769 7.13e-52 ylmC - - S - - - sporulation protein
NNAPIBNL_02770 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NNAPIBNL_02771 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NNAPIBNL_02772 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNAPIBNL_02773 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NNAPIBNL_02774 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
NNAPIBNL_02775 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NNAPIBNL_02776 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNAPIBNL_02777 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NNAPIBNL_02778 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNAPIBNL_02779 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NNAPIBNL_02780 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNAPIBNL_02781 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NNAPIBNL_02782 4.15e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NNAPIBNL_02783 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNAPIBNL_02784 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NNAPIBNL_02785 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NNAPIBNL_02786 2.68e-176 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NNAPIBNL_02787 1.17e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNAPIBNL_02788 2.37e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNAPIBNL_02789 3.5e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNAPIBNL_02790 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NNAPIBNL_02791 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NNAPIBNL_02792 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NNAPIBNL_02793 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NNAPIBNL_02794 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NNAPIBNL_02795 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NNAPIBNL_02796 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NNAPIBNL_02797 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NNAPIBNL_02798 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NNAPIBNL_02799 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NNAPIBNL_02800 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NNAPIBNL_02801 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NNAPIBNL_02802 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NNAPIBNL_02803 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_02804 3.89e-265 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNAPIBNL_02805 8.02e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNAPIBNL_02806 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
NNAPIBNL_02807 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNAPIBNL_02808 9e-101 yrrD - - S - - - protein conserved in bacteria
NNAPIBNL_02809 8.4e-42 yrzR - - - - - - -
NNAPIBNL_02810 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
NNAPIBNL_02811 1.41e-134 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNAPIBNL_02812 4.74e-136 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NNAPIBNL_02813 5.82e-185 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNAPIBNL_02814 1.43e-164 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNAPIBNL_02815 4.09e-231 yrrI - - S - - - AI-2E family transporter
NNAPIBNL_02816 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNAPIBNL_02817 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
NNAPIBNL_02818 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNAPIBNL_02819 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
NNAPIBNL_02820 7.74e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNAPIBNL_02821 4.49e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NNAPIBNL_02822 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NNAPIBNL_02823 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NNAPIBNL_02824 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NNAPIBNL_02825 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNAPIBNL_02826 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NNAPIBNL_02827 8.77e-104 yrrS - - S - - - Protein of unknown function (DUF1510)
NNAPIBNL_02828 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
NNAPIBNL_02829 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NNAPIBNL_02830 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNAPIBNL_02831 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NNAPIBNL_02832 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NNAPIBNL_02833 1.35e-46 yrhC - - S - - - YrhC-like protein
NNAPIBNL_02834 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
NNAPIBNL_02835 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NNAPIBNL_02836 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NNAPIBNL_02837 4.62e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NNAPIBNL_02838 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NNAPIBNL_02839 3.67e-120 yrhH - - Q - - - methyltransferase
NNAPIBNL_02840 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NNAPIBNL_02841 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NNAPIBNL_02842 1.32e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_02843 5.33e-211 yybE - - K - - - Transcriptional regulator
NNAPIBNL_02844 1.88e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NNAPIBNL_02845 9.54e-229 romA - - S - - - Beta-lactamase superfamily domain
NNAPIBNL_02846 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NNAPIBNL_02847 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_02848 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NNAPIBNL_02849 2.38e-167 - - - K - - - Helix-turn-helix domain, rpiR family
NNAPIBNL_02850 7.33e-67 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNAPIBNL_02851 5.2e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NNAPIBNL_02852 1.14e-187 supH - - S - - - hydrolase
NNAPIBNL_02854 2.76e-120 - - - S - - - DinB family
NNAPIBNL_02855 6.08e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NNAPIBNL_02856 5.34e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_02857 1.84e-126 yqaC - - F - - - adenylate kinase activity
NNAPIBNL_02859 3.5e-47 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NNAPIBNL_02860 1.02e-79 - - - K - - - Transcriptional regulator PadR-like family
NNAPIBNL_02861 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NNAPIBNL_02862 6.77e-21 xkdG - - S - - - Phage capsid family
NNAPIBNL_02863 1.29e-89 - - - K - - - MerR family transcriptional regulator
NNAPIBNL_02864 1.23e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
NNAPIBNL_02865 8.72e-34 xkdR - - S - - - Protein of unknown function (DUF2577)
NNAPIBNL_02866 8.03e-141 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NNAPIBNL_02867 8.55e-19 xkdS - - S - - - Protein of unknown function (DUF2634)
NNAPIBNL_02868 5.49e-13 - - - S - - - SMI1-KNR4 cell-wall
NNAPIBNL_02872 8.14e-25 - - - - - - - -
NNAPIBNL_02873 2.68e-135 lin0465 - - S - - - DJ-1/PfpI family
NNAPIBNL_02874 1.28e-206 - - - K ko:K13572 - ko00000,ko03051 HTH domain
NNAPIBNL_02876 2.82e-142 mchB - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 Thioesterase involved in non-ribosomal peptide biosynthesis
NNAPIBNL_02877 5.94e-257 glyA_1 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNAPIBNL_02878 3.41e-151 - - - S - - - Winged helix DNA-binding domain
NNAPIBNL_02879 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
NNAPIBNL_02880 1.69e-220 - 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 phenylacetate-CoA ligase activity
NNAPIBNL_02881 1.71e-224 - 4.1.3.27, 4.2.99.21, 5.4.4.2 - EH ko:K01657,ko:K04781 ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I domain protein
NNAPIBNL_02882 2.93e-98 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 TIGRFAM glutamine amidotransferase of anthranilate synthase
NNAPIBNL_02883 7.65e-201 smvA - - EGP ko:K08167 - ko00000,ko00002,ko01504,ko02000 Major facilitator superfamily
NNAPIBNL_02886 1.18e-50 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNAPIBNL_02887 1.46e-194 - - - L - - - AAA ATPase domain
NNAPIBNL_02888 1.82e-17 - - - L ko:K06400 - ko00000 Recombinase
NNAPIBNL_02889 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_02890 2.47e-274 - - - EGP - - - Transmembrane secretion effector
NNAPIBNL_02891 9.72e-08 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NNAPIBNL_02893 3.41e-137 yqeD - - S - - - SNARE associated Golgi protein
NNAPIBNL_02894 3.16e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NNAPIBNL_02895 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NNAPIBNL_02897 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NNAPIBNL_02898 1.87e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NNAPIBNL_02899 2.83e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NNAPIBNL_02900 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NNAPIBNL_02901 1.38e-138 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNAPIBNL_02902 3.25e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NNAPIBNL_02903 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNAPIBNL_02904 1.98e-177 yqeM - - Q - - - Methyltransferase
NNAPIBNL_02905 1.14e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNAPIBNL_02906 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NNAPIBNL_02907 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NNAPIBNL_02908 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NNAPIBNL_02909 6.09e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NNAPIBNL_02910 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NNAPIBNL_02911 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NNAPIBNL_02912 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NNAPIBNL_02913 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
NNAPIBNL_02914 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNAPIBNL_02915 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NNAPIBNL_02916 1.11e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNAPIBNL_02917 1.99e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNAPIBNL_02918 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NNAPIBNL_02919 6.71e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNAPIBNL_02920 1.27e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NNAPIBNL_02921 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNAPIBNL_02922 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NNAPIBNL_02923 1.99e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NNAPIBNL_02924 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NNAPIBNL_02925 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NNAPIBNL_02926 3.91e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NNAPIBNL_02927 1.22e-186 yqfA - - S - - - UPF0365 protein
NNAPIBNL_02928 2.58e-48 yqfB - - - - - - -
NNAPIBNL_02929 3.57e-61 yqfC - - S - - - sporulation protein YqfC
NNAPIBNL_02930 3.96e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NNAPIBNL_02931 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NNAPIBNL_02932 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NNAPIBNL_02933 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNAPIBNL_02934 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NNAPIBNL_02935 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NNAPIBNL_02936 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNAPIBNL_02937 6e-24 - - - S - - - YqzL-like protein
NNAPIBNL_02938 1.9e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NNAPIBNL_02939 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NNAPIBNL_02940 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NNAPIBNL_02941 3.41e-144 ccpN - - K - - - CBS domain
NNAPIBNL_02942 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NNAPIBNL_02943 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NNAPIBNL_02944 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNAPIBNL_02945 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNAPIBNL_02946 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NNAPIBNL_02947 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NNAPIBNL_02948 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNAPIBNL_02949 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NNAPIBNL_02950 7.12e-57 yqfQ - - S - - - YqfQ-like protein
NNAPIBNL_02951 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNAPIBNL_02952 9.16e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NNAPIBNL_02953 2.9e-47 yqfT - - S - - - Protein of unknown function (DUF2624)
NNAPIBNL_02954 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_02955 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NNAPIBNL_02956 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NNAPIBNL_02957 3.9e-79 yqfX - - S - - - membrane
NNAPIBNL_02958 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NNAPIBNL_02959 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
NNAPIBNL_02960 8.5e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
NNAPIBNL_02961 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NNAPIBNL_02962 8.52e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NNAPIBNL_02963 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NNAPIBNL_02964 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NNAPIBNL_02965 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NNAPIBNL_02966 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NNAPIBNL_02967 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NNAPIBNL_02968 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNAPIBNL_02969 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNAPIBNL_02970 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NNAPIBNL_02971 3.42e-68 yqzD - - - - - - -
NNAPIBNL_02972 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NNAPIBNL_02973 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNAPIBNL_02974 5.38e-11 yqgO - - - - - - -
NNAPIBNL_02975 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NNAPIBNL_02976 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
NNAPIBNL_02977 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NNAPIBNL_02978 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NNAPIBNL_02979 1.57e-239 yqgU - - - - - - -
NNAPIBNL_02980 2.02e-63 dglA - - S - - - Thiamine-binding protein
NNAPIBNL_02981 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
NNAPIBNL_02982 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NNAPIBNL_02983 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NNAPIBNL_02984 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NNAPIBNL_02986 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNAPIBNL_02987 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NNAPIBNL_02988 1.34e-231 yqxL - - P - - - Mg2 transporter protein
NNAPIBNL_02989 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_02990 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NNAPIBNL_02992 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NNAPIBNL_02993 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NNAPIBNL_02994 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NNAPIBNL_02995 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNAPIBNL_02996 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NNAPIBNL_02997 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NNAPIBNL_02998 1.15e-140 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NNAPIBNL_02999 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NNAPIBNL_03001 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNAPIBNL_03002 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NNAPIBNL_03003 2.49e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NNAPIBNL_03004 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NNAPIBNL_03005 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NNAPIBNL_03006 6.18e-222 ykvI - - S - - - membrane
NNAPIBNL_03008 1.81e-196 - - - - - - - -
NNAPIBNL_03009 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NNAPIBNL_03010 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NNAPIBNL_03011 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NNAPIBNL_03012 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NNAPIBNL_03013 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
NNAPIBNL_03014 1.56e-34 ykvS - - S - - - protein conserved in bacteria
NNAPIBNL_03015 8.76e-38 - - - - - - - -
NNAPIBNL_03016 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NNAPIBNL_03017 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_03018 1.04e-105 stoA - - CO - - - thiol-disulfide
NNAPIBNL_03019 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NNAPIBNL_03020 1.51e-259 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NNAPIBNL_03021 4.21e-217 ykvZ - - K - - - Transcriptional regulator
NNAPIBNL_03022 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NNAPIBNL_03023 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NNAPIBNL_03024 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NNAPIBNL_03025 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNAPIBNL_03026 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03027 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NNAPIBNL_03028 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NNAPIBNL_03029 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NNAPIBNL_03030 9.19e-65 - - - - - - - -
NNAPIBNL_03031 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
NNAPIBNL_03032 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NNAPIBNL_03033 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_03034 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NNAPIBNL_03035 2.22e-15 - - - - - - - -
NNAPIBNL_03036 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NNAPIBNL_03037 1.45e-107 ykyB - - S - - - YkyB-like protein
NNAPIBNL_03038 2e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03039 3.48e-114 ykuD - - S - - - protein conserved in bacteria
NNAPIBNL_03040 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NNAPIBNL_03041 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_03043 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
NNAPIBNL_03044 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
NNAPIBNL_03045 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
NNAPIBNL_03046 2.63e-36 ykzF - - S - - - Antirepressor AbbA
NNAPIBNL_03047 7.03e-98 ykuL - - S - - - CBS domain
NNAPIBNL_03048 1.08e-214 ccpC - - K - - - Transcriptional regulator
NNAPIBNL_03049 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
NNAPIBNL_03050 1.07e-207 ykuO - - - - - - -
NNAPIBNL_03051 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
NNAPIBNL_03052 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNAPIBNL_03053 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNAPIBNL_03054 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
NNAPIBNL_03055 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NNAPIBNL_03057 7.8e-23 ykuV - - CO - - - thiol-disulfide
NNAPIBNL_03058 1.14e-58 ykuV - - CO - - - thiol-disulfide
NNAPIBNL_03060 3.55e-125 rok - - K - - - Repressor of ComK
NNAPIBNL_03061 8.39e-201 yknT - - - ko:K06437 - ko00000 -
NNAPIBNL_03062 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NNAPIBNL_03063 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NNAPIBNL_03064 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NNAPIBNL_03065 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NNAPIBNL_03066 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NNAPIBNL_03067 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NNAPIBNL_03068 5.77e-134 yknW - - S - - - Yip1 domain
NNAPIBNL_03069 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNAPIBNL_03070 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_03071 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NNAPIBNL_03072 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03073 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NNAPIBNL_03074 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NNAPIBNL_03075 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNAPIBNL_03076 3.54e-48 ykoA - - - - - - -
NNAPIBNL_03077 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNAPIBNL_03078 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNAPIBNL_03079 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NNAPIBNL_03080 7.7e-19 - - - S - - - Uncharacterized protein YkpC
NNAPIBNL_03081 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NNAPIBNL_03082 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NNAPIBNL_03083 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NNAPIBNL_03084 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NNAPIBNL_03085 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NNAPIBNL_03086 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NNAPIBNL_03087 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNAPIBNL_03088 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
NNAPIBNL_03089 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
NNAPIBNL_03090 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNAPIBNL_03091 1.04e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNAPIBNL_03092 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
NNAPIBNL_03093 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NNAPIBNL_03094 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NNAPIBNL_03095 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNAPIBNL_03096 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NNAPIBNL_03097 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NNAPIBNL_03098 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NNAPIBNL_03099 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NNAPIBNL_03100 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
NNAPIBNL_03101 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
NNAPIBNL_03102 7.89e-32 ykzI - - - - - - -
NNAPIBNL_03103 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NNAPIBNL_03104 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
NNAPIBNL_03105 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NNAPIBNL_03106 9.3e-32 ylaA - - - - - - -
NNAPIBNL_03108 1.97e-52 ylaE - - - - - - -
NNAPIBNL_03109 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
NNAPIBNL_03110 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NNAPIBNL_03111 1.41e-64 - - - S - - - YlaH-like protein
NNAPIBNL_03112 7.95e-45 ylaI - - S - - - protein conserved in bacteria
NNAPIBNL_03113 2.67e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNAPIBNL_03114 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NNAPIBNL_03115 4.45e-104 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NNAPIBNL_03116 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NNAPIBNL_03117 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
NNAPIBNL_03118 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NNAPIBNL_03119 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NNAPIBNL_03120 5.26e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NNAPIBNL_03121 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
NNAPIBNL_03122 9.03e-33 - - - S - - - Protein of unknown function (DUF3212)
NNAPIBNL_03123 1.41e-99 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NNAPIBNL_03124 3.25e-64 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NNAPIBNL_03125 4.02e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NNAPIBNL_03126 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNAPIBNL_03127 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NNAPIBNL_03128 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NNAPIBNL_03129 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NNAPIBNL_03130 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NNAPIBNL_03131 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NNAPIBNL_03132 3.69e-165 yfmS - - NT - - - chemotaxis protein
NNAPIBNL_03133 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NNAPIBNL_03134 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
NNAPIBNL_03135 7.91e-271 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03136 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NNAPIBNL_03137 7.97e-273 yfnE - - S - - - Glycosyltransferase like family 2
NNAPIBNL_03138 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NNAPIBNL_03139 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NNAPIBNL_03140 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NNAPIBNL_03141 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NNAPIBNL_03143 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NNAPIBNL_03144 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NNAPIBNL_03145 3.35e-246 yetM - - CH - - - FAD binding domain
NNAPIBNL_03146 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_03147 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NNAPIBNL_03148 2.59e-73 - - - H - - - riboflavin kinase activity
NNAPIBNL_03149 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
NNAPIBNL_03150 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NNAPIBNL_03151 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNAPIBNL_03152 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NNAPIBNL_03153 1.26e-147 yetF - - S - - - membrane
NNAPIBNL_03155 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
NNAPIBNL_03156 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NNAPIBNL_03157 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
NNAPIBNL_03158 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NNAPIBNL_03159 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NNAPIBNL_03161 1.27e-161 yeeN - - K - - - transcriptional regulatory protein
NNAPIBNL_03162 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
NNAPIBNL_03163 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NNAPIBNL_03164 2.48e-66 - - - S - - - Protein of unknown function, DUF600
NNAPIBNL_03165 2.35e-73 - - - S - - - Protein of unknown function, DUF600
NNAPIBNL_03166 5.92e-51 - - - S - - - Protein of unknown function, DUF600
NNAPIBNL_03167 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NNAPIBNL_03168 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NNAPIBNL_03169 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NNAPIBNL_03170 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNAPIBNL_03171 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NNAPIBNL_03172 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NNAPIBNL_03173 1.01e-189 yerO - - K - - - Transcriptional regulator
NNAPIBNL_03174 5.04e-199 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNAPIBNL_03176 8.39e-34 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNAPIBNL_03177 1.61e-214 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NNAPIBNL_03178 4.89e-262 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NNAPIBNL_03179 1.3e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NNAPIBNL_03180 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NNAPIBNL_03181 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNAPIBNL_03182 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NNAPIBNL_03183 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NNAPIBNL_03184 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NNAPIBNL_03185 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNAPIBNL_03186 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NNAPIBNL_03187 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NNAPIBNL_03188 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NNAPIBNL_03189 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NNAPIBNL_03190 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NNAPIBNL_03191 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NNAPIBNL_03192 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NNAPIBNL_03193 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NNAPIBNL_03194 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NNAPIBNL_03195 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NNAPIBNL_03196 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NNAPIBNL_03197 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NNAPIBNL_03198 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NNAPIBNL_03199 2.51e-192 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NNAPIBNL_03200 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NNAPIBNL_03201 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NNAPIBNL_03202 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNAPIBNL_03203 3.61e-34 - - - - - - - -
NNAPIBNL_03204 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NNAPIBNL_03205 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NNAPIBNL_03206 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NNAPIBNL_03207 1.98e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NNAPIBNL_03208 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NNAPIBNL_03209 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NNAPIBNL_03210 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NNAPIBNL_03211 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NNAPIBNL_03212 3.63e-110 ysxD - - - - - - -
NNAPIBNL_03213 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NNAPIBNL_03214 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NNAPIBNL_03215 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NNAPIBNL_03216 8.92e-291 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNAPIBNL_03217 2.43e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNAPIBNL_03218 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
NNAPIBNL_03219 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNAPIBNL_03220 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NNAPIBNL_03221 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NNAPIBNL_03222 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NNAPIBNL_03223 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NNAPIBNL_03224 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NNAPIBNL_03225 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NNAPIBNL_03230 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NNAPIBNL_03231 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNAPIBNL_03232 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NNAPIBNL_03233 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NNAPIBNL_03234 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NNAPIBNL_03235 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_03236 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03237 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NNAPIBNL_03238 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NNAPIBNL_03239 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NNAPIBNL_03240 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NNAPIBNL_03241 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
NNAPIBNL_03242 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNAPIBNL_03243 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNAPIBNL_03244 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NNAPIBNL_03245 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NNAPIBNL_03246 5.59e-224 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NNAPIBNL_03247 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NNAPIBNL_03248 6.9e-121 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NNAPIBNL_03249 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
NNAPIBNL_03250 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NNAPIBNL_03251 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNAPIBNL_03252 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNAPIBNL_03253 1.27e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNAPIBNL_03254 1.94e-165 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNAPIBNL_03255 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NNAPIBNL_03256 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NNAPIBNL_03257 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
NNAPIBNL_03258 5e-309 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NNAPIBNL_03259 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NNAPIBNL_03260 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NNAPIBNL_03261 1.27e-186 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NNAPIBNL_03262 8.11e-211 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NNAPIBNL_03263 2.69e-312 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NNAPIBNL_03264 2.36e-269 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NNAPIBNL_03265 1.33e-175 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NNAPIBNL_03266 2.82e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NNAPIBNL_03267 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NNAPIBNL_03268 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NNAPIBNL_03269 4.34e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NNAPIBNL_03270 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NNAPIBNL_03271 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
NNAPIBNL_03272 5.91e-51 ysdA - - S - - - Membrane
NNAPIBNL_03273 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNAPIBNL_03274 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NNAPIBNL_03275 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNAPIBNL_03276 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NNAPIBNL_03277 3.04e-64 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
NNAPIBNL_03278 4.78e-164 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NNAPIBNL_03279 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_03280 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NNAPIBNL_03281 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNAPIBNL_03282 6.12e-192 ytxC - - S - - - YtxC-like family
NNAPIBNL_03283 2.03e-136 ytxB - - S - - - SNARE associated Golgi protein
NNAPIBNL_03284 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NNAPIBNL_03285 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NNAPIBNL_03286 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNAPIBNL_03287 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NNAPIBNL_03288 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNAPIBNL_03289 7.74e-86 ytcD - - K - - - Transcriptional regulator
NNAPIBNL_03290 3.31e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NNAPIBNL_03291 4.68e-198 ytbE - - S - - - reductase
NNAPIBNL_03292 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNAPIBNL_03293 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
NNAPIBNL_03294 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNAPIBNL_03295 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNAPIBNL_03296 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NNAPIBNL_03297 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_03298 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NNAPIBNL_03299 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NNAPIBNL_03300 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NNAPIBNL_03301 1.14e-95 ytwI - - S - - - membrane
NNAPIBNL_03302 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
NNAPIBNL_03303 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NNAPIBNL_03304 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NNAPIBNL_03305 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NNAPIBNL_03306 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NNAPIBNL_03307 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNAPIBNL_03308 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NNAPIBNL_03309 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NNAPIBNL_03310 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
NNAPIBNL_03311 3.08e-113 ytrI - - - - - - -
NNAPIBNL_03312 1.17e-30 - - - - - - - -
NNAPIBNL_03313 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NNAPIBNL_03314 3.44e-60 ytpI - - S - - - YtpI-like protein
NNAPIBNL_03315 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
NNAPIBNL_03316 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
NNAPIBNL_03317 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_03319 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NNAPIBNL_03320 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNAPIBNL_03321 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NNAPIBNL_03322 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNAPIBNL_03323 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NNAPIBNL_03324 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNAPIBNL_03325 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
NNAPIBNL_03326 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
NNAPIBNL_03327 1.31e-103 yteJ - - S - - - RDD family
NNAPIBNL_03328 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NNAPIBNL_03329 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNAPIBNL_03330 0.0 ytcJ - - S - - - amidohydrolase
NNAPIBNL_03331 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNAPIBNL_03332 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NNAPIBNL_03333 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNAPIBNL_03334 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NNAPIBNL_03335 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NNAPIBNL_03336 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNAPIBNL_03337 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NNAPIBNL_03338 2.22e-137 yttP - - K - - - Transcriptional regulator
NNAPIBNL_03339 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NNAPIBNL_03340 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NNAPIBNL_03341 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNAPIBNL_03342 1.22e-272 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NNAPIBNL_03345 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NNAPIBNL_03347 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNAPIBNL_03348 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNAPIBNL_03349 1.06e-188 - - - K - - - Transcriptional regulator
NNAPIBNL_03350 7.21e-154 ygaZ - - E - - - AzlC protein
NNAPIBNL_03351 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NNAPIBNL_03352 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNAPIBNL_03353 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NNAPIBNL_03354 3.32e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NNAPIBNL_03355 9.68e-138 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NNAPIBNL_03356 3.3e-282 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NNAPIBNL_03357 1.87e-127 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NNAPIBNL_03358 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NNAPIBNL_03359 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NNAPIBNL_03360 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NNAPIBNL_03361 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
NNAPIBNL_03362 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NNAPIBNL_03363 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNAPIBNL_03364 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NNAPIBNL_03365 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNAPIBNL_03366 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNAPIBNL_03367 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
NNAPIBNL_03368 2.23e-75 ytpP - - CO - - - Thioredoxin
NNAPIBNL_03369 5.33e-98 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NNAPIBNL_03370 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NNAPIBNL_03371 9.96e-69 ytzB - - S - - - small secreted protein
NNAPIBNL_03372 1.43e-287 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NNAPIBNL_03373 2.98e-90 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NNAPIBNL_03374 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NNAPIBNL_03375 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNAPIBNL_03376 4.54e-59 ytzH - - S - - - YtzH-like protein
NNAPIBNL_03377 3.42e-198 ytmP - - M - - - Phosphotransferase
NNAPIBNL_03378 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NNAPIBNL_03379 2.86e-198 ytlQ - - - - - - -
NNAPIBNL_03380 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NNAPIBNL_03381 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NNAPIBNL_03382 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NNAPIBNL_03383 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NNAPIBNL_03384 1.72e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NNAPIBNL_03385 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NNAPIBNL_03386 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NNAPIBNL_03387 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NNAPIBNL_03388 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_03389 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NNAPIBNL_03390 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NNAPIBNL_03391 3.57e-35 yteV - - S - - - Sporulation protein Cse60
NNAPIBNL_03392 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03393 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NNAPIBNL_03394 6.99e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NNAPIBNL_03395 1.2e-147 yoxB - - - - - - -
NNAPIBNL_03396 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNAPIBNL_03397 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NNAPIBNL_03398 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NNAPIBNL_03399 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNAPIBNL_03400 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNAPIBNL_03401 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03402 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NNAPIBNL_03403 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NNAPIBNL_03404 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNAPIBNL_03405 1.91e-66 - - - K - - - Helix-turn-helix domain
NNAPIBNL_03406 5.29e-237 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
NNAPIBNL_03407 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NNAPIBNL_03408 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
NNAPIBNL_03409 7.69e-123 - - - L - - - Integrase
NNAPIBNL_03411 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NNAPIBNL_03412 1.31e-305 yoeA - - V - - - MATE efflux family protein
NNAPIBNL_03413 1.56e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NNAPIBNL_03414 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NNAPIBNL_03415 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_03416 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
NNAPIBNL_03417 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NNAPIBNL_03418 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NNAPIBNL_03419 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NNAPIBNL_03420 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
NNAPIBNL_03421 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
NNAPIBNL_03422 1.72e-232 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NNAPIBNL_03423 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NNAPIBNL_03424 3.26e-100 yisT - - S - - - DinB family
NNAPIBNL_03425 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NNAPIBNL_03426 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NNAPIBNL_03427 1.77e-201 yisR - - K - - - Transcriptional regulator
NNAPIBNL_03428 1.69e-307 yisQ - - V - - - Mate efflux family protein
NNAPIBNL_03429 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NNAPIBNL_03430 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NNAPIBNL_03431 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
NNAPIBNL_03432 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNAPIBNL_03433 4.48e-78 yisL - - S - - - UPF0344 protein
NNAPIBNL_03434 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NNAPIBNL_03435 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
NNAPIBNL_03436 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NNAPIBNL_03437 5.87e-44 gerPB - - S ko:K06300 - ko00000 cell differentiation
NNAPIBNL_03438 3.28e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NNAPIBNL_03439 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NNAPIBNL_03440 2.37e-77 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NNAPIBNL_03441 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NNAPIBNL_03442 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
NNAPIBNL_03443 5.79e-187 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NNAPIBNL_03444 2.71e-110 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NNAPIBNL_03445 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NNAPIBNL_03446 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NNAPIBNL_03447 6.63e-216 rsiX - - - - - - -
NNAPIBNL_03448 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNAPIBNL_03449 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNAPIBNL_03450 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NNAPIBNL_03451 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NNAPIBNL_03452 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NNAPIBNL_03453 1.84e-123 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NNAPIBNL_03454 8.85e-110 ypbE - - M - - - Lysin motif
NNAPIBNL_03455 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
NNAPIBNL_03456 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NNAPIBNL_03457 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NNAPIBNL_03458 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NNAPIBNL_03459 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NNAPIBNL_03460 6.31e-57 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NNAPIBNL_03461 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_03462 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NNAPIBNL_03463 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NNAPIBNL_03464 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NNAPIBNL_03465 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NNAPIBNL_03466 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NNAPIBNL_03467 3.9e-245 yceH - - P - - - Belongs to the TelA family
NNAPIBNL_03468 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NNAPIBNL_03470 8.61e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NNAPIBNL_03471 2.01e-184 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NNAPIBNL_03472 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NNAPIBNL_03473 6.41e-261 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NNAPIBNL_03474 2.88e-238 ycgA - - S - - - Membrane
NNAPIBNL_03475 4.22e-33 ycgA - - S - - - Membrane
NNAPIBNL_03476 5.14e-54 ycgB - - - - - - -
NNAPIBNL_03477 2.85e-15 - - - S - - - RDD family
NNAPIBNL_03478 1.55e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NNAPIBNL_03479 0.0 mdr - - EGP - - - the major facilitator superfamily
NNAPIBNL_03480 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_03482 1.15e-54 ycgF - - E - - - Lysine exporter protein LysE YggA
NNAPIBNL_03483 6.64e-76 ycgF - - E - - - Lysine exporter protein LysE YggA
NNAPIBNL_03484 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NNAPIBNL_03485 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NNAPIBNL_03486 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NNAPIBNL_03487 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNAPIBNL_03488 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NNAPIBNL_03489 1.47e-121 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03490 6.16e-148 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03491 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NNAPIBNL_03492 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NNAPIBNL_03493 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NNAPIBNL_03494 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NNAPIBNL_03495 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NNAPIBNL_03496 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNAPIBNL_03497 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NNAPIBNL_03498 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NNAPIBNL_03499 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NNAPIBNL_03500 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NNAPIBNL_03501 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NNAPIBNL_03502 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NNAPIBNL_03503 9.85e-281 yciC - - S - - - GTPases (G3E family)
NNAPIBNL_03504 3.05e-277 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NNAPIBNL_03505 3.65e-94 yckC - - S - - - membrane
NNAPIBNL_03506 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
NNAPIBNL_03507 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NNAPIBNL_03508 7.34e-86 nin - - S - - - Competence protein J (ComJ)
NNAPIBNL_03509 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
NNAPIBNL_03510 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NNAPIBNL_03511 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NNAPIBNL_03512 2.89e-84 hxlR - - K - - - transcriptional
NNAPIBNL_03517 6.29e-91 - - - L - - - Prophage endopeptidase tail
NNAPIBNL_03518 4.16e-66 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NNAPIBNL_03519 3.68e-153 - - - D - - - phage tail tape measure protein
NNAPIBNL_03520 1.09e-49 - - - D - - - phage tail tape measure protein
NNAPIBNL_03523 9.4e-61 - - - N - - - domain, Protein
NNAPIBNL_03526 3.72e-34 - - - - - - - -
NNAPIBNL_03529 3.56e-187 - - - S - - - Family of unknown function (DUF5309)
NNAPIBNL_03530 3.57e-32 - - - - - - - -
NNAPIBNL_03531 4.13e-101 - - - S - - - Phage minor capsid protein 2
NNAPIBNL_03532 6.42e-202 - - - - - - - -
NNAPIBNL_03533 6.16e-35 - - - S - - - Helix-turn-helix of insertion element transposase
NNAPIBNL_03534 0.0 - - - S - - - TIGRFAM Phage
NNAPIBNL_03535 1.12e-86 - - - L - - - Phage integrase family
NNAPIBNL_03536 2.65e-09 - - - - - - - -
NNAPIBNL_03539 1.61e-24 - - - - - - - -
NNAPIBNL_03540 4.53e-99 - - - N - - - bacterial-type flagellum assembly
NNAPIBNL_03541 1.34e-14 - - - K - - - Cro/C1-type HTH DNA-binding domain
NNAPIBNL_03545 6.54e-61 - - - - - - - -
NNAPIBNL_03546 7.61e-32 - - - - - - - -
NNAPIBNL_03548 3.64e-151 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NNAPIBNL_03550 3.73e-172 - - - - - - - -
NNAPIBNL_03551 1.58e-65 - - - - - - - -
NNAPIBNL_03552 3.3e-63 - - - K - - - Sigma-70, region 4
NNAPIBNL_03554 1.22e-211 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NNAPIBNL_03555 4.6e-77 - - - H - - - dephospho-CoA kinase activity
NNAPIBNL_03556 8.04e-51 - - - - - - - -
NNAPIBNL_03557 2.2e-82 - - - S - - - SprT-like family
NNAPIBNL_03558 6.78e-44 - - - S - - - protein conserved in bacteria
NNAPIBNL_03559 2.13e-129 - 2.1.1.148 - F ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 ko00000,ko00001,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
NNAPIBNL_03562 3.31e-87 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
NNAPIBNL_03564 1.27e-193 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNAPIBNL_03566 1.19e-227 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNAPIBNL_03567 0.000318 - - - S - - - Transcriptional regulator
NNAPIBNL_03568 2.78e-151 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNAPIBNL_03569 1.87e-54 - - - F - - - Belongs to the NrdI family
NNAPIBNL_03574 1.91e-33 - - - - - - - -
NNAPIBNL_03575 1.09e-204 - - - - - - - -
NNAPIBNL_03577 0.0 - - - L - - - 3'-5' exonuclease
NNAPIBNL_03579 6.45e-25 - - - - - - - -
NNAPIBNL_03580 1.77e-62 - - - - - - - -
NNAPIBNL_03581 1.4e-103 - - - - - - - -
NNAPIBNL_03588 3.87e-164 - - - L - - - Toprim-like
NNAPIBNL_03589 3.73e-175 - - - L - - - DnaB-like helicase C terminal domain
NNAPIBNL_03592 5.15e-138 - - - L ko:K02315 - ko00000,ko03032 DNA-dependent DNA replication
NNAPIBNL_03595 9.9e-78 - - - - - - - -
NNAPIBNL_03596 5.63e-21 - - - - - - - -
NNAPIBNL_03601 6.51e-51 - - - - - - - -
NNAPIBNL_03602 2.12e-50 - - - S - - - Helix-turn-helix domain
NNAPIBNL_03605 4.7e-126 - - - L - - - Belongs to the 'phage' integrase family
NNAPIBNL_03621 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNAPIBNL_03622 2.26e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NNAPIBNL_03623 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
NNAPIBNL_03624 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
NNAPIBNL_03625 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NNAPIBNL_03626 2.09e-303 ymfH - - S - - - zinc protease
NNAPIBNL_03627 8.12e-300 albE - - S - - - Peptidase M16
NNAPIBNL_03628 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NNAPIBNL_03629 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_03630 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03631 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03632 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NNAPIBNL_03633 7.4e-41 - - - S - - - YlzJ-like protein
NNAPIBNL_03634 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NNAPIBNL_03635 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNAPIBNL_03636 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNAPIBNL_03637 3.69e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NNAPIBNL_03638 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNAPIBNL_03639 6.97e-131 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NNAPIBNL_03640 4.32e-202 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NNAPIBNL_03641 2.17e-56 ymxH - - S - - - YlmC YmxH family
NNAPIBNL_03642 9.79e-298 mlpA - - S - - - Belongs to the peptidase M16 family
NNAPIBNL_03643 6.6e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NNAPIBNL_03644 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NNAPIBNL_03645 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNAPIBNL_03646 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NNAPIBNL_03647 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNAPIBNL_03648 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNAPIBNL_03649 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NNAPIBNL_03650 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNAPIBNL_03651 6.16e-63 ylxQ - - J - - - ribosomal protein
NNAPIBNL_03652 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NNAPIBNL_03653 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NNAPIBNL_03654 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NNAPIBNL_03655 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNAPIBNL_03656 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNAPIBNL_03657 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NNAPIBNL_03658 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NNAPIBNL_03659 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NNAPIBNL_03660 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNAPIBNL_03661 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNAPIBNL_03662 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NNAPIBNL_03663 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNAPIBNL_03664 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NNAPIBNL_03665 2.54e-84 ylxL - - - - - - -
NNAPIBNL_03666 1.14e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NNAPIBNL_03667 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NNAPIBNL_03668 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NNAPIBNL_03669 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NNAPIBNL_03670 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NNAPIBNL_03671 5.21e-222 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NNAPIBNL_03672 6.76e-146 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NNAPIBNL_03673 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NNAPIBNL_03674 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
NNAPIBNL_03675 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNAPIBNL_03676 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNAPIBNL_03677 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNAPIBNL_03678 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNAPIBNL_03679 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NNAPIBNL_03680 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NNAPIBNL_03681 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NNAPIBNL_03682 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NNAPIBNL_03684 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NNAPIBNL_03685 4.16e-281 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNAPIBNL_03686 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NNAPIBNL_03687 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NNAPIBNL_03688 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NNAPIBNL_03689 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NNAPIBNL_03690 1.64e-224 yaaC - - S - - - YaaC-like Protein
NNAPIBNL_03691 6.18e-66 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NNAPIBNL_03692 0.0 yhaN - - L - - - AAA domain
NNAPIBNL_03693 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NNAPIBNL_03694 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
NNAPIBNL_03695 3.2e-182 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNAPIBNL_03696 4.32e-122 yhaK - - S - - - Putative zincin peptidase
NNAPIBNL_03697 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NNAPIBNL_03698 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NNAPIBNL_03699 1.58e-53 yhaH - - S - - - YtxH-like protein
NNAPIBNL_03700 2.55e-24 - - - - - - - -
NNAPIBNL_03701 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
NNAPIBNL_03702 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NNAPIBNL_03703 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NNAPIBNL_03704 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NNAPIBNL_03705 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NNAPIBNL_03706 9.96e-152 ecsC - - S - - - EcsC protein family
NNAPIBNL_03707 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NNAPIBNL_03708 1.65e-303 yhfA - - C - - - membrane
NNAPIBNL_03709 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NNAPIBNL_03710 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NNAPIBNL_03711 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NNAPIBNL_03712 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NNAPIBNL_03713 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NNAPIBNL_03714 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_03715 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NNAPIBNL_03716 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNAPIBNL_03718 1.66e-247 yhfE - - G - - - peptidase M42
NNAPIBNL_03719 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNAPIBNL_03720 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NNAPIBNL_03721 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NNAPIBNL_03722 3.92e-137 yhfK - - GM - - - NmrA-like family
NNAPIBNL_03723 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NNAPIBNL_03724 9.31e-84 yhfM - - - - - - -
NNAPIBNL_03725 1.33e-293 yhfN - - O - - - Peptidase M48
NNAPIBNL_03726 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNAPIBNL_03727 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NNAPIBNL_03728 4.57e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NNAPIBNL_03729 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NNAPIBNL_03730 1.98e-302 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NNAPIBNL_03731 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NNAPIBNL_03732 3.11e-167 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NNAPIBNL_03733 5.89e-68 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NNAPIBNL_03734 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NNAPIBNL_03735 9.14e-09 - - - D - - - Phage tail tape measure protein
NNAPIBNL_03736 3.35e-59 - - - S - - - Phage tail protein
NNAPIBNL_03737 2.45e-26 - - - S - - - Prophage endopeptidase tail
NNAPIBNL_03739 2.7e-128 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NNAPIBNL_03740 3.24e-92 - - - S - - - Domain of unknown function (DUF2479)
NNAPIBNL_03743 4.67e-29 bhlA - - S - - - BhlA holin family
NNAPIBNL_03744 1.99e-33 xhlB - - S - - - SPP1 phage holin
NNAPIBNL_03745 5.67e-84 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_03748 3.07e-90 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNAPIBNL_03749 8.53e-13 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNAPIBNL_03750 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NNAPIBNL_03751 1.47e-49 yfhS - - - - - - -
NNAPIBNL_03752 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NNAPIBNL_03753 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NNAPIBNL_03754 1.4e-49 ygaB - - S - - - YgaB-like protein
NNAPIBNL_03755 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NNAPIBNL_03756 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NNAPIBNL_03757 1.76e-237 ygaE - - S - - - Membrane
NNAPIBNL_03758 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NNAPIBNL_03759 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NNAPIBNL_03760 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NNAPIBNL_03761 1.1e-73 ygzB - - S - - - UPF0295 protein
NNAPIBNL_03762 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
NNAPIBNL_03763 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNAPIBNL_03764 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NNAPIBNL_03765 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNAPIBNL_03766 2.46e-315 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_03767 4.89e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NNAPIBNL_03768 2.66e-289 gerKC - - S ko:K06297 - ko00000 spore germination
NNAPIBNL_03769 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NNAPIBNL_03771 0.0 yclG - - M - - - Pectate lyase superfamily protein
NNAPIBNL_03772 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NNAPIBNL_03773 4.77e-76 yclD - - - - - - -
NNAPIBNL_03774 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NNAPIBNL_03775 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NNAPIBNL_03776 2.91e-197 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NNAPIBNL_03777 1.41e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NNAPIBNL_03778 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NNAPIBNL_03779 1.32e-167 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NNAPIBNL_03780 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
NNAPIBNL_03781 5.87e-155 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NNAPIBNL_03782 5.89e-314 - - - E - - - Aminotransferase class I and II
NNAPIBNL_03783 1.14e-175 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NNAPIBNL_03784 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NNAPIBNL_03785 1.9e-303 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_03786 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NNAPIBNL_03787 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NNAPIBNL_03788 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNAPIBNL_03789 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
NNAPIBNL_03790 3.52e-149 yoaK - - S - - - Membrane
NNAPIBNL_03791 9.32e-81 ymzB - - - - - - -
NNAPIBNL_03792 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NNAPIBNL_03793 2.64e-07 - - - - - - - -
NNAPIBNL_03794 3.08e-151 ymaC - - S - - - Replication protein
NNAPIBNL_03795 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NNAPIBNL_03796 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNAPIBNL_03797 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NNAPIBNL_03799 9.08e-72 ymaF - - S - - - YmaF family
NNAPIBNL_03800 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNAPIBNL_03801 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NNAPIBNL_03802 1.87e-53 - - - - - - - -
NNAPIBNL_03803 2.31e-29 ymzA - - - - - - -
NNAPIBNL_03804 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NNAPIBNL_03805 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNAPIBNL_03806 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNAPIBNL_03807 2.21e-132 ymaB - - S - - - MutT family
NNAPIBNL_03808 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_03809 2e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NNAPIBNL_03810 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NNAPIBNL_03811 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNAPIBNL_03812 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NNAPIBNL_03813 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NNAPIBNL_03814 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NNAPIBNL_03815 1.1e-192 - - - L - - - Belongs to the 'phage' integrase family
NNAPIBNL_03817 1.36e-111 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NNAPIBNL_03818 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
NNAPIBNL_03819 1.82e-187 - - - V - - - HNH endonuclease
NNAPIBNL_03820 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NNAPIBNL_03821 3.18e-67 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NNAPIBNL_03823 2.08e-162 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NNAPIBNL_03824 2.1e-52 - - - S - - - YolD-like protein
NNAPIBNL_03825 8.79e-283 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NNAPIBNL_03826 5.27e-79 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NNAPIBNL_03827 1.08e-59 cmoA - - Q ko:K15256 - ko00000,ko01000,ko03016 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
NNAPIBNL_03828 9.95e-38 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_03829 2.54e-265 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NNAPIBNL_03830 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NNAPIBNL_03831 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NNAPIBNL_03832 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
NNAPIBNL_03833 3.77e-225 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NNAPIBNL_03835 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NNAPIBNL_03836 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNAPIBNL_03837 3.63e-110 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NNAPIBNL_03838 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNAPIBNL_03839 4.31e-260 pbpX - - V - - - Beta-lactamase
NNAPIBNL_03840 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NNAPIBNL_03841 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NNAPIBNL_03842 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NNAPIBNL_03843 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NNAPIBNL_03844 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNAPIBNL_03845 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NNAPIBNL_03846 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NNAPIBNL_03847 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
NNAPIBNL_03848 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNAPIBNL_03849 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNAPIBNL_03850 3.58e-160 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NNAPIBNL_03851 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNAPIBNL_03852 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NNAPIBNL_03853 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNAPIBNL_03854 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NNAPIBNL_03855 9.98e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NNAPIBNL_03856 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NNAPIBNL_03857 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NNAPIBNL_03858 1.39e-207 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NNAPIBNL_03859 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NNAPIBNL_03860 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
NNAPIBNL_03861 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NNAPIBNL_03862 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NNAPIBNL_03863 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NNAPIBNL_03864 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NNAPIBNL_03865 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNAPIBNL_03866 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NNAPIBNL_03867 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NNAPIBNL_03868 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NNAPIBNL_03869 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NNAPIBNL_03870 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NNAPIBNL_03871 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NNAPIBNL_03872 3.29e-238 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNAPIBNL_03873 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NNAPIBNL_03874 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NNAPIBNL_03875 3.62e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NNAPIBNL_03876 6.16e-134 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NNAPIBNL_03877 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NNAPIBNL_03878 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NNAPIBNL_03879 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NNAPIBNL_03880 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NNAPIBNL_03881 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NNAPIBNL_03882 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NNAPIBNL_03883 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NNAPIBNL_03884 1.02e-88 yngA - - S - - - membrane
NNAPIBNL_03885 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NNAPIBNL_03886 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
NNAPIBNL_03887 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NNAPIBNL_03888 2.54e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NNAPIBNL_03889 2.16e-208 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NNAPIBNL_03890 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NNAPIBNL_03891 1.6e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NNAPIBNL_03892 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNAPIBNL_03893 5.24e-43 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNAPIBNL_03894 6.97e-264 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NNAPIBNL_03895 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NNAPIBNL_03896 9.31e-83 yngL - - S - - - Protein of unknown function (DUF1360)
NNAPIBNL_03897 2.85e-315 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
NNAPIBNL_03898 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NNAPIBNL_03899 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNAPIBNL_03900 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNAPIBNL_03901 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
NNAPIBNL_03902 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NNAPIBNL_03903 9.18e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNAPIBNL_03904 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NNAPIBNL_03905 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
NNAPIBNL_03906 1.16e-133 yrbG - - S - - - membrane
NNAPIBNL_03907 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NNAPIBNL_03908 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
NNAPIBNL_03909 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NNAPIBNL_03910 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NNAPIBNL_03911 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NNAPIBNL_03912 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NNAPIBNL_03913 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNAPIBNL_03914 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNAPIBNL_03915 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNAPIBNL_03916 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NNAPIBNL_03919 1.44e-110 yobS - - K - - - Transcriptional regulator
NNAPIBNL_03920 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NNAPIBNL_03921 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NNAPIBNL_03924 1.52e-38 - - - - - - - -
NNAPIBNL_03925 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_03927 6.3e-36 yoaF - - - - - - -
NNAPIBNL_03928 1.17e-272 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNAPIBNL_03929 7.87e-49 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NNAPIBNL_03930 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
NNAPIBNL_03931 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
NNAPIBNL_03932 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
NNAPIBNL_03933 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NNAPIBNL_03934 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NNAPIBNL_03935 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NNAPIBNL_03936 1.23e-125 ypjA - - S - - - membrane
NNAPIBNL_03937 1.09e-177 ypjB - - S - - - sporulation protein
NNAPIBNL_03938 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NNAPIBNL_03939 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NNAPIBNL_03940 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NNAPIBNL_03941 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNAPIBNL_03942 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NNAPIBNL_03943 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NNAPIBNL_03944 7.01e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NNAPIBNL_03945 1.53e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNAPIBNL_03946 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNAPIBNL_03947 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NNAPIBNL_03948 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NNAPIBNL_03949 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NNAPIBNL_03950 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NNAPIBNL_03951 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NNAPIBNL_03952 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NNAPIBNL_03953 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NNAPIBNL_03954 7.32e-105 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NNAPIBNL_03955 1.42e-102 yuaE - - S - - - DinB superfamily
NNAPIBNL_03956 1.21e-134 - - - S - - - MOSC domain
NNAPIBNL_03957 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NNAPIBNL_03958 4.03e-35 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NNAPIBNL_03961 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNAPIBNL_03962 5.36e-113 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NNAPIBNL_03968 7.42e-35 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNAPIBNL_03969 6.91e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNAPIBNL_03970 7.22e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NNAPIBNL_03971 4.92e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NNAPIBNL_03972 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NNAPIBNL_03973 6.97e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNAPIBNL_03974 4.85e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NNAPIBNL_03975 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NNAPIBNL_03976 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NNAPIBNL_03977 6.07e-77 yloU - - S - - - protein conserved in bacteria
NNAPIBNL_03978 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NNAPIBNL_03979 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NNAPIBNL_03980 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NNAPIBNL_03981 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNAPIBNL_03982 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NNAPIBNL_03983 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNAPIBNL_03984 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NNAPIBNL_03985 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NNAPIBNL_03986 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNAPIBNL_03987 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNAPIBNL_03988 3.6e-250 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NNAPIBNL_03989 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNAPIBNL_03990 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NNAPIBNL_03991 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NNAPIBNL_03992 8e-194 yloC - - S - - - stress-induced protein
NNAPIBNL_03993 2.08e-283 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NNAPIBNL_03994 5.49e-42 yhzC - - S - - - IDEAL
NNAPIBNL_03995 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NNAPIBNL_03996 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NNAPIBNL_03997 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
NNAPIBNL_03998 1.53e-156 yrpD - - S - - - Domain of unknown function, YrpD
NNAPIBNL_03999 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
NNAPIBNL_04000 2.64e-63 - - - S - - - Belongs to the UPF0145 family
NNAPIBNL_04001 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NNAPIBNL_04002 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
NNAPIBNL_04003 2.3e-76 yhjD - - - - - - -
NNAPIBNL_04004 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
NNAPIBNL_04005 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NNAPIBNL_04006 0.0 yhjG - - CH - - - FAD binding domain
NNAPIBNL_04007 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NNAPIBNL_04008 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
NNAPIBNL_04009 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_04010 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
NNAPIBNL_04011 3.47e-108 yhjR - - S - - - Rubrerythrin
NNAPIBNL_04012 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
NNAPIBNL_04013 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NNAPIBNL_04014 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NNAPIBNL_04015 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNAPIBNL_04016 4.59e-309 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNAPIBNL_04019 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
NNAPIBNL_04020 0.0 - - - I - - - PLD-like domain
NNAPIBNL_04021 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
NNAPIBNL_04022 6.56e-192 - - - S - - - membrane
NNAPIBNL_04023 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
NNAPIBNL_04024 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
NNAPIBNL_04025 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NNAPIBNL_04026 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NNAPIBNL_04027 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NNAPIBNL_04028 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
NNAPIBNL_04030 4.04e-103 - - - - - - - -
NNAPIBNL_04031 2.84e-123 tnpR - - L - - - resolvase
NNAPIBNL_04032 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
NNAPIBNL_04033 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NNAPIBNL_04034 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNAPIBNL_04035 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
NNAPIBNL_04036 9.33e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
NNAPIBNL_04037 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NNAPIBNL_04038 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NNAPIBNL_04039 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NNAPIBNL_04040 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NNAPIBNL_04041 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NNAPIBNL_04042 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNAPIBNL_04043 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NNAPIBNL_04044 2.17e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NNAPIBNL_04045 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NNAPIBNL_04046 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NNAPIBNL_04047 0.0 ylqG - - - - - - -
NNAPIBNL_04048 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNAPIBNL_04049 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNAPIBNL_04050 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNAPIBNL_04051 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NNAPIBNL_04052 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NNAPIBNL_04053 9.64e-127 yheG - - GM - - - NAD(P)H-binding
NNAPIBNL_04055 1.91e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NNAPIBNL_04056 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
NNAPIBNL_04057 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
NNAPIBNL_04058 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
NNAPIBNL_04059 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
NNAPIBNL_04060 5.48e-69 yheA - - S - - - Belongs to the UPF0342 family
NNAPIBNL_04061 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NNAPIBNL_04062 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NNAPIBNL_04063 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
NNAPIBNL_04064 9.07e-263 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NNAPIBNL_04065 6.25e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NNAPIBNL_04067 4.59e-172 yhaR - - I - - - enoyl-CoA hydratase
NNAPIBNL_04068 1.21e-20 - - - S - - - YhzD-like protein
NNAPIBNL_04069 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NNAPIBNL_04070 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NNAPIBNL_04072 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NNAPIBNL_04073 1.33e-43 - - - S - - - TM2 domain
NNAPIBNL_04074 0.0 yobO - - M - - - Pectate lyase superfamily protein
NNAPIBNL_04076 1.97e-119 yvgO - - - - - - -
NNAPIBNL_04077 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NNAPIBNL_04078 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
NNAPIBNL_04079 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NNAPIBNL_04080 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
NNAPIBNL_04082 1.87e-53 - - - - - - - -
NNAPIBNL_04084 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
NNAPIBNL_04085 1.52e-164 yoaP - - K - - - YoaP-like
NNAPIBNL_04086 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NNAPIBNL_04087 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
NNAPIBNL_04088 2.04e-10 - - - - - - - -
NNAPIBNL_04089 5.82e-16 - - - - - - - -
NNAPIBNL_04090 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NNAPIBNL_04091 1.08e-86 dinB - - S - - - DinB family
NNAPIBNL_04100 4.25e-118 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNAPIBNL_04101 1.6e-13 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNAPIBNL_04102 4.77e-203 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNAPIBNL_04103 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NNAPIBNL_04104 5.69e-249 yoaB - - EGP - - - the major facilitator superfamily
NNAPIBNL_04105 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NNAPIBNL_04106 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NNAPIBNL_04107 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NNAPIBNL_04108 1.71e-54 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NNAPIBNL_04109 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NNAPIBNL_04110 2.03e-228 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NNAPIBNL_04111 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NNAPIBNL_04112 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NNAPIBNL_04113 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NNAPIBNL_04114 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NNAPIBNL_04115 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NNAPIBNL_04116 9e-173 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NNAPIBNL_04117 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNAPIBNL_04118 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNAPIBNL_04119 1.93e-156 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NNAPIBNL_04120 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NNAPIBNL_04121 6.66e-229 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNAPIBNL_04122 1.84e-121 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)