Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HEOCKMHB_00016	4.7e-126	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEOCKMHB_00019	2.12e-50	-	-	-	S	-	-	-	Helix-turn-helix domain
HEOCKMHB_00020	6.51e-51	-	-	-	-	-	-	-	-
HEOCKMHB_00025	5.63e-21	-	-	-	-	-	-	-	-
HEOCKMHB_00026	9.9e-78	-	-	-	-	-	-	-	-
HEOCKMHB_00029	5.15e-138	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
HEOCKMHB_00032	3.73e-175	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HEOCKMHB_00033	3.87e-164	-	-	-	L	-	-	-	Toprim-like
HEOCKMHB_00040	1.4e-103	-	-	-	-	-	-	-	-
HEOCKMHB_00041	1.77e-62	-	-	-	-	-	-	-	-
HEOCKMHB_00042	6.45e-25	-	-	-	-	-	-	-	-
HEOCKMHB_00044	0.0	-	-	-	L	-	-	-	3'-5' exonuclease
HEOCKMHB_00046	1.09e-204	-	-	-	-	-	-	-	-
HEOCKMHB_00047	1.91e-33	-	-	-	-	-	-	-	-
HEOCKMHB_00052	1.87e-54	-	-	-	F	-	-	-	Belongs to the NrdI family
HEOCKMHB_00053	2.78e-151	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOCKMHB_00054	0.000318	-	-	-	S	-	-	-	Transcriptional regulator
HEOCKMHB_00055	1.19e-227	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOCKMHB_00057	1.27e-193	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOCKMHB_00059	3.31e-87	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
HEOCKMHB_00062	2.13e-129	-	2.1.1.148	-	F	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HEOCKMHB_00063	6.78e-44	-	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00064	2.2e-82	-	-	-	S	-	-	-	SprT-like family
HEOCKMHB_00065	8.04e-51	-	-	-	-	-	-	-	-
HEOCKMHB_00066	4.6e-77	-	-	-	H	-	-	-	dephospho-CoA kinase activity
HEOCKMHB_00067	1.22e-211	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HEOCKMHB_00069	3.3e-63	-	-	-	K	-	-	-	Sigma-70, region 4
HEOCKMHB_00070	1.58e-65	-	-	-	-	-	-	-	-
HEOCKMHB_00071	3.73e-172	-	-	-	-	-	-	-	-
HEOCKMHB_00073	3.64e-151	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HEOCKMHB_00075	7.61e-32	-	-	-	-	-	-	-	-
HEOCKMHB_00076	6.54e-61	-	-	-	-	-	-	-	-
HEOCKMHB_00080	1.34e-14	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEOCKMHB_00081	4.53e-99	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HEOCKMHB_00082	1.61e-24	-	-	-	-	-	-	-	-
HEOCKMHB_00085	2.65e-09	-	-	-	-	-	-	-	-
HEOCKMHB_00086	1.12e-86	-	-	-	L	-	-	-	Phage integrase family
HEOCKMHB_00087	0.0	-	-	-	S	-	-	-	TIGRFAM Phage
HEOCKMHB_00088	6.16e-35	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
HEOCKMHB_00089	6.42e-202	-	-	-	-	-	-	-	-
HEOCKMHB_00090	4.13e-101	-	-	-	S	-	-	-	Phage minor capsid protein 2
HEOCKMHB_00091	3.57e-32	-	-	-	-	-	-	-	-
HEOCKMHB_00092	3.56e-187	-	-	-	S	-	-	-	Family of unknown function (DUF5309)
HEOCKMHB_00095	3.72e-34	-	-	-	-	-	-	-	-
HEOCKMHB_00098	9.4e-61	-	-	-	N	-	-	-	domain, Protein
HEOCKMHB_00101	1.09e-49	-	-	-	D	-	-	-	phage tail tape measure protein
HEOCKMHB_00102	3.68e-153	-	-	-	D	-	-	-	phage tail tape measure protein
HEOCKMHB_00103	4.16e-66	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEOCKMHB_00104	6.29e-91	-	-	-	L	-	-	-	Prophage endopeptidase tail
HEOCKMHB_00105	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HEOCKMHB_00106	2.47e-104	-	-	-	-	-	-	-	-
HEOCKMHB_00109	1.66e-39	-	-	-	S	-	-	-	BhlA holin family
HEOCKMHB_00110	7.04e-186	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEOCKMHB_00111	1.04e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HEOCKMHB_00115	4.25e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HEOCKMHB_00117	2.25e-311	-	-	-	C	-	-	-	Na+/H+ antiporter family
HEOCKMHB_00118	2.28e-156	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HEOCKMHB_00119	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEOCKMHB_00120	3.15e-313	ygaK	-	-	C	-	-	-	Berberine and berberine like
HEOCKMHB_00122	1.69e-291	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HEOCKMHB_00123	2.33e-185	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEOCKMHB_00124	6.2e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00125	5.45e-170	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00126	5.17e-165	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00127	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEOCKMHB_00128	2.39e-227	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HEOCKMHB_00129	1.02e-176	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEOCKMHB_00130	5.5e-217	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HEOCKMHB_00131	6.5e-183	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEOCKMHB_00132	5.74e-266	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HEOCKMHB_00134	1.62e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEOCKMHB_00135	2.4e-102	ygaO	-	-	-	-	-	-	-
HEOCKMHB_00136	5.45e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00138	1.34e-138	yhzB	-	-	S	-	-	-	B3/4 domain
HEOCKMHB_00139	2.14e-280	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEOCKMHB_00140	8.37e-216	yhbB	-	-	S	-	-	-	Putative amidase domain
HEOCKMHB_00141	2.31e-110	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEOCKMHB_00142	3.35e-132	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HEOCKMHB_00143	2.51e-76	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEOCKMHB_00144	7.48e-85	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEOCKMHB_00145	4.51e-08	-	-	-	-	-	-	-	-
HEOCKMHB_00146	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HEOCKMHB_00147	1.74e-275	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HEOCKMHB_00148	5.43e-94	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HEOCKMHB_00149	2.98e-130	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HEOCKMHB_00150	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEOCKMHB_00151	2.61e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEOCKMHB_00152	1.03e-65	yhcC	-	-	-	-	-	-	-
HEOCKMHB_00153	7.54e-65	-	-	-	-	-	-	-	-
HEOCKMHB_00154	3.06e-77	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00155	8.89e-147	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_00156	3.74e-212	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_00157	1.87e-201	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEOCKMHB_00158	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HEOCKMHB_00159	6.9e-161	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEOCKMHB_00160	2.76e-230	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HEOCKMHB_00161	1.01e-290	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOCKMHB_00162	1.79e-49	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEOCKMHB_00163	5.08e-60	yhcM	-	-	-	-	-	-	-
HEOCKMHB_00164	6.26e-101	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOCKMHB_00165	3.99e-199	yhcP	-	-	-	-	-	-	-
HEOCKMHB_00166	2.2e-149	yhcQ	-	-	M	-	-	-	Spore coat protein
HEOCKMHB_00167	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEOCKMHB_00168	3.17e-128	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HEOCKMHB_00169	2.24e-207	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEOCKMHB_00170	1.88e-83	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HEOCKMHB_00171	5.88e-89	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HEOCKMHB_00172	1.33e-158	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HEOCKMHB_00173	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEOCKMHB_00174	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOCKMHB_00175	2.26e-129	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEOCKMHB_00176	2.6e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEOCKMHB_00177	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEOCKMHB_00178	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEOCKMHB_00179	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HEOCKMHB_00180	2.73e-247	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_00181	5.61e-139	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOCKMHB_00182	2.89e-108	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HEOCKMHB_00183	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HEOCKMHB_00184	2.33e-68	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEOCKMHB_00185	1.69e-282	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEOCKMHB_00186	1.49e-93	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HEOCKMHB_00187	5.72e-314	ygxB	-	-	M	-	-	-	Conserved TM helix
HEOCKMHB_00188	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HEOCKMHB_00189	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HEOCKMHB_00190	2.28e-166	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEOCKMHB_00191	1.7e-201	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00192	2.19e-250	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEOCKMHB_00193	3.42e-200	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_00194	1.1e-311	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HEOCKMHB_00195	4.63e-264	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOCKMHB_00196	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HEOCKMHB_00197	2.03e-249	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HEOCKMHB_00198	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_00199	4.04e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEOCKMHB_00200	2.66e-305	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEOCKMHB_00201	2.3e-91	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HEOCKMHB_00202	9.37e-276	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEOCKMHB_00203	7.35e-290	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOCKMHB_00204	5.48e-314	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEOCKMHB_00205	1.68e-69	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEOCKMHB_00206	4.22e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEOCKMHB_00207	1.26e-156	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEOCKMHB_00208	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HEOCKMHB_00209	5.39e-252	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HEOCKMHB_00210	3.53e-172	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEOCKMHB_00211	6.85e-192	nodB1	-	-	G	-	-	-	deacetylase
HEOCKMHB_00212	1.05e-191	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEOCKMHB_00213	9.13e-126	pksA	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_00214	1.17e-118	ymcC	-	-	S	-	-	-	Membrane
HEOCKMHB_00215	3.96e-107	-	-	-	T	-	-	-	universal stress protein
HEOCKMHB_00216	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOCKMHB_00217	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOCKMHB_00218	9.64e-127	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HEOCKMHB_00220	1.91e-38	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEOCKMHB_00221	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HEOCKMHB_00222	5.52e-316	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEOCKMHB_00223	2.7e-257	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEOCKMHB_00224	3.13e-254	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HEOCKMHB_00225	5.48e-69	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HEOCKMHB_00226	2.49e-197	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEOCKMHB_00227	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HEOCKMHB_00228	1.48e-311	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HEOCKMHB_00229	9.07e-263	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HEOCKMHB_00230	1.09e-92	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEOCKMHB_00232	4.59e-172	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HEOCKMHB_00233	1.21e-20	-	-	-	S	-	-	-	YhzD-like protein
HEOCKMHB_00234	3.45e-209	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_00235	2.67e-274	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HEOCKMHB_00236	2.2e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HEOCKMHB_00237	0.0	yhaN	-	-	L	-	-	-	AAA domain
HEOCKMHB_00238	3.05e-96	yhaN	-	-	L	-	-	-	AAA domain
HEOCKMHB_00239	3.38e-224	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HEOCKMHB_00240	8.23e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HEOCKMHB_00241	3.2e-182	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEOCKMHB_00242	4.32e-122	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HEOCKMHB_00243	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HEOCKMHB_00244	1.07e-142	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HEOCKMHB_00245	1.58e-53	yhaH	-	-	S	-	-	-	YtxH-like protein
HEOCKMHB_00246	2.55e-24	-	-	-	-	-	-	-	-
HEOCKMHB_00247	1.12e-97	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HEOCKMHB_00248	1.49e-252	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEOCKMHB_00249	5.82e-105	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEOCKMHB_00250	2.13e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HEOCKMHB_00251	3.4e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEOCKMHB_00252	9.96e-152	ecsC	-	-	S	-	-	-	EcsC protein family
HEOCKMHB_00253	1.68e-274	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEOCKMHB_00254	1.65e-303	yhfA	-	-	C	-	-	-	membrane
HEOCKMHB_00255	2.98e-115	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HEOCKMHB_00256	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEOCKMHB_00257	9.19e-253	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEOCKMHB_00258	3.4e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HEOCKMHB_00259	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEOCKMHB_00260	5.15e-130	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00261	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HEOCKMHB_00262	2.04e-226	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEOCKMHB_00264	1.66e-247	yhfE	-	-	G	-	-	-	peptidase M42
HEOCKMHB_00265	3.75e-286	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOCKMHB_00266	2.4e-173	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEOCKMHB_00267	1.07e-240	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HEOCKMHB_00268	3.92e-137	yhfK	-	-	GM	-	-	-	NmrA-like family
HEOCKMHB_00269	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEOCKMHB_00270	9.31e-84	yhfM	-	-	-	-	-	-	-
HEOCKMHB_00271	1.33e-293	yhfN	-	-	O	-	-	-	Peptidase M48
HEOCKMHB_00272	1.24e-258	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEOCKMHB_00273	1.78e-163	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEOCKMHB_00274	4.57e-129	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HEOCKMHB_00275	8.49e-245	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEOCKMHB_00276	1.98e-302	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEOCKMHB_00277	2.32e-110	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HEOCKMHB_00278	3.11e-167	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HEOCKMHB_00279	5.89e-68	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HEOCKMHB_00280	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HEOCKMHB_00281	2.73e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_00282	5.49e-42	yhzC	-	-	S	-	-	-	IDEAL
HEOCKMHB_00283	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HEOCKMHB_00284	4.21e-74	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HEOCKMHB_00285	1.28e-213	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
HEOCKMHB_00286	1.53e-156	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HEOCKMHB_00287	7.11e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HEOCKMHB_00288	2.64e-63	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HEOCKMHB_00289	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOCKMHB_00290	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEOCKMHB_00291	2.3e-76	yhjD	-	-	-	-	-	-	-
HEOCKMHB_00292	8.02e-136	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_00293	1.3e-116	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEOCKMHB_00294	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HEOCKMHB_00295	9.88e-120	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_00296	2.03e-254	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HEOCKMHB_00297	1.56e-260	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_00298	1.24e-138	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HEOCKMHB_00299	3.47e-108	yhjR	-	-	S	-	-	-	Rubrerythrin
HEOCKMHB_00300	8.81e-152	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEOCKMHB_00301	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HEOCKMHB_00302	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HEOCKMHB_00303	7.47e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEOCKMHB_00304	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HEOCKMHB_00305	3.36e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HEOCKMHB_00306	5.49e-42	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HEOCKMHB_00307	2.37e-77	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HEOCKMHB_00308	1.44e-31	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HEOCKMHB_00309	3.28e-104	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HEOCKMHB_00310	5.87e-44	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HEOCKMHB_00311	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HEOCKMHB_00312	2.45e-13	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEOCKMHB_00313	2.25e-211	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEOCKMHB_00314	4.48e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HEOCKMHB_00315	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEOCKMHB_00316	5.25e-115	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HEOCKMHB_00317	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEOCKMHB_00318	6.09e-150	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HEOCKMHB_00319	1.69e-307	yisQ	-	-	V	-	-	-	Mate efflux family protein
HEOCKMHB_00320	1.77e-201	yisR	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_00321	3.87e-179	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEOCKMHB_00322	2.32e-195	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HEOCKMHB_00323	3.26e-100	yisT	-	-	S	-	-	-	DinB family
HEOCKMHB_00324	8.48e-96	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HEOCKMHB_00325	1.72e-232	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOCKMHB_00326	9.1e-82	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HEOCKMHB_00327	6.78e-100	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_00328	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEOCKMHB_00329	7.44e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HEOCKMHB_00330	3.3e-199	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HEOCKMHB_00331	2.3e-186	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HEOCKMHB_00332	1.06e-288	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HEOCKMHB_00333	4.22e-293	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HEOCKMHB_00334	8.05e-196	yitS	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00335	4.62e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_00336	3.05e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HEOCKMHB_00337	4.3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HEOCKMHB_00338	1.49e-11	-	-	-	-	-	-	-	-
HEOCKMHB_00339	3.84e-192	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEOCKMHB_00340	1.98e-182	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEOCKMHB_00341	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HEOCKMHB_00342	3.29e-92	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEOCKMHB_00343	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HEOCKMHB_00344	4.44e-117	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HEOCKMHB_00345	1.26e-246	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEOCKMHB_00346	4.35e-282	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEOCKMHB_00347	3.58e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HEOCKMHB_00348	5.32e-266	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HEOCKMHB_00349	4.59e-248	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEOCKMHB_00350	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HEOCKMHB_00351	1.78e-220	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEOCKMHB_00352	2.07e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
HEOCKMHB_00353	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HEOCKMHB_00354	6.59e-171	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HEOCKMHB_00355	7.04e-127	yjaV	-	-	-	-	-	-	-
HEOCKMHB_00356	8.66e-209	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HEOCKMHB_00357	3.74e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HEOCKMHB_00358	1.46e-37	yjzB	-	-	-	-	-	-	-
HEOCKMHB_00359	1.26e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEOCKMHB_00360	1.24e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOCKMHB_00361	2.47e-179	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HEOCKMHB_00362	1.81e-226	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00363	4.48e-232	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00364	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HEOCKMHB_00365	8.55e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00366	7.81e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00367	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HEOCKMHB_00368	8.74e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HEOCKMHB_00369	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEOCKMHB_00370	2.08e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00371	2.42e-208	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00372	1.96e-252	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00373	1e-216	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00374	3.04e-280	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HEOCKMHB_00375	1.04e-130	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOCKMHB_00376	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEOCKMHB_00377	2.28e-140	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HEOCKMHB_00378	2.3e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEOCKMHB_00379	1.14e-256	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEOCKMHB_00380	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HEOCKMHB_00381	3.14e-27	-	-	-	-	-	-	-	-
HEOCKMHB_00382	9.23e-215	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEOCKMHB_00383	6.79e-91	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HEOCKMHB_00384	1.15e-138	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEOCKMHB_00385	8.1e-118	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00386	3.37e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HEOCKMHB_00387	3.67e-138	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HEOCKMHB_00388	6.92e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEOCKMHB_00389	2.7e-201	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEOCKMHB_00390	1.1e-176	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEOCKMHB_00391	1.5e-108	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEOCKMHB_00392	2.06e-170	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEOCKMHB_00393	2.91e-132	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HEOCKMHB_00394	8.33e-255	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HEOCKMHB_00395	5.3e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HEOCKMHB_00396	1.81e-173	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEOCKMHB_00397	7.09e-228	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEOCKMHB_00398	2.99e-180	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEOCKMHB_00399	1.38e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HEOCKMHB_00400	2.47e-100	yjbX	-	-	S	-	-	-	Spore coat protein
HEOCKMHB_00401	3.35e-105	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HEOCKMHB_00402	1.75e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HEOCKMHB_00403	3.55e-98	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HEOCKMHB_00404	1.02e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
HEOCKMHB_00405	4.61e-69	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HEOCKMHB_00406	1.69e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEOCKMHB_00409	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEOCKMHB_00410	1.05e-50	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HEOCKMHB_00411	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEOCKMHB_00412	1.62e-44	-	-	-	-	-	-	-	-
HEOCKMHB_00413	6.53e-167	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HEOCKMHB_00414	2e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEOCKMHB_00415	1.09e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEOCKMHB_00416	1.19e-45	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HEOCKMHB_00417	6.83e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOCKMHB_00418	6.7e-119	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HEOCKMHB_00419	1.79e-157	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HEOCKMHB_00420	3.46e-265	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEOCKMHB_00421	5.84e-273	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEOCKMHB_00423	2.89e-73	-	-	-	-	-	-	-	-
HEOCKMHB_00424	2.31e-90	-	-	-	S	-	-	-	Bacterial EndoU nuclease
HEOCKMHB_00425	1.06e-42	-	-	-	-	-	-	-	-
HEOCKMHB_00426	3.75e-116	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HEOCKMHB_00427	1.61e-128	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase
HEOCKMHB_00428	2.21e-28	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HEOCKMHB_00429	9.5e-81	-	-	-	H	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_00431	7.99e-240	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HEOCKMHB_00432	2.8e-119	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HEOCKMHB_00433	3.84e-226	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HEOCKMHB_00434	9.18e-49	-	-	-	S	-	-	-	YolD-like protein
HEOCKMHB_00435	2.46e-57	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOCKMHB_00436	4.74e-38	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEOCKMHB_00440	0.000667	KLHL36	-	-	T	ko:K13958	-	ko00000,ko04121	protein modification by small protein conjugation
HEOCKMHB_00441	4.57e-21	-	-	-	N	-	-	-	Kelch motif
HEOCKMHB_00443	3.78e-196	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HEOCKMHB_00444	7.1e-58	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEOCKMHB_00445	5.5e-302	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HEOCKMHB_00446	1.09e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_00447	7.71e-277	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HEOCKMHB_00448	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOCKMHB_00449	3.63e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_00450	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEOCKMHB_00451	1.39e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEOCKMHB_00452	1.67e-151	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HEOCKMHB_00453	3.81e-45	-	-	-	-	-	-	-	-
HEOCKMHB_00454	4.16e-69	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_00455	2.77e-133	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEOCKMHB_00457	1.07e-28	yjfB	-	-	S	-	-	-	Putative motility protein
HEOCKMHB_00458	6.25e-83	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HEOCKMHB_00459	4.05e-122	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HEOCKMHB_00460	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEOCKMHB_00461	3.47e-150	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HEOCKMHB_00462	1.44e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEOCKMHB_00463	1.73e-40	-	-	-	-	-	-	-	-
HEOCKMHB_00464	3.96e-275	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEOCKMHB_00465	7.68e-274	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEOCKMHB_00466	5.21e-88	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEOCKMHB_00467	4.85e-98	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEOCKMHB_00468	1.44e-65	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEOCKMHB_00469	4.94e-42	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00470	5.99e-220	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HEOCKMHB_00471	1.47e-110	yjlB	-	-	S	-	-	-	Cupin domain
HEOCKMHB_00472	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEOCKMHB_00473	8.37e-278	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEOCKMHB_00474	2.92e-80	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HEOCKMHB_00475	1.62e-231	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HEOCKMHB_00476	3.18e-203	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HEOCKMHB_00477	1.29e-112	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEOCKMHB_00478	2.12e-165	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEOCKMHB_00480	7.24e-164	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEOCKMHB_00481	9.4e-100	yjoA	-	-	S	-	-	-	DinB family
HEOCKMHB_00482	3.13e-274	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEOCKMHB_00484	5.72e-213	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEOCKMHB_00485	3.19e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
HEOCKMHB_00486	2.69e-128	yjqB	-	-	S	-	-	-	phage-related replication protein
HEOCKMHB_00487	2.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEOCKMHB_00488	1.27e-72	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_00490	8.33e-185	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HEOCKMHB_00494	3.15e-105	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOCKMHB_00495	1.37e-139	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HEOCKMHB_00496	3.35e-263	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HEOCKMHB_00497	1.72e-302	xkdE3	-	-	S	-	-	-	portal protein
HEOCKMHB_00498	8.47e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HEOCKMHB_00499	3.38e-202	xkdG	-	-	S	-	-	-	Phage capsid family
HEOCKMHB_00501	2.41e-77	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEOCKMHB_00502	1.82e-75	xkdJ	-	-	-	-	-	-	-
HEOCKMHB_00503	3.86e-21	-	-	-	-	-	-	-	-
HEOCKMHB_00504	4.44e-285	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HEOCKMHB_00505	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HEOCKMHB_00506	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HEOCKMHB_00507	4.33e-27	-	-	-	-	-	-	-	-
HEOCKMHB_00508	7.01e-277	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HEOCKMHB_00509	1.88e-144	xkdP	-	-	S	-	-	-	Lysin motif
HEOCKMHB_00510	2.78e-208	xkdQ	-	-	G	-	-	-	NLP P60 protein
HEOCKMHB_00511	3.05e-44	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HEOCKMHB_00512	2.35e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HEOCKMHB_00513	7.44e-208	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEOCKMHB_00514	3.37e-111	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HEOCKMHB_00515	1.48e-36	-	-	-	-	-	-	-	-
HEOCKMHB_00516	1.04e-194	-	-	-	-	-	-	-	-
HEOCKMHB_00518	1.05e-36	xkdX	-	-	-	-	-	-	-
HEOCKMHB_00519	2.97e-167	xepA	-	-	-	-	-	-	-
HEOCKMHB_00520	6.44e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HEOCKMHB_00521	2.62e-49	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEOCKMHB_00522	2.43e-206	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_00523	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HEOCKMHB_00524	1.05e-169	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HEOCKMHB_00525	2.36e-224	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HEOCKMHB_00526	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEOCKMHB_00527	2.11e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HEOCKMHB_00528	1.75e-227	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEOCKMHB_00529	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEOCKMHB_00530	3.02e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOCKMHB_00532	2.08e-266	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOCKMHB_00533	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HEOCKMHB_00534	4.18e-198	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HEOCKMHB_00535	2.68e-202	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00536	3.22e-218	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEOCKMHB_00537	1.49e-230	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00538	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEOCKMHB_00539	8.59e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HEOCKMHB_00540	2e-244	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HEOCKMHB_00541	1.74e-198	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEOCKMHB_00542	1.49e-227	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_00543	6.11e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HEOCKMHB_00544	1.45e-179	ykgA	-	-	E	-	-	-	Amidinotransferase
HEOCKMHB_00545	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HEOCKMHB_00546	1.01e-118	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEOCKMHB_00547	8.24e-64	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEOCKMHB_00548	1.22e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEOCKMHB_00549	1.03e-211	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEOCKMHB_00550	3.28e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEOCKMHB_00551	1.35e-281	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEOCKMHB_00552	1.89e-90	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEOCKMHB_00553	6.88e-102	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HEOCKMHB_00554	1.3e-90	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEOCKMHB_00555	1.46e-70	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEOCKMHB_00557	2.15e-260	-	-	-	M	-	-	-	Glycosyl transferase family 2
HEOCKMHB_00558	8.96e-151	-	-	-	K	-	-	-	Collagen triple helix repeat
HEOCKMHB_00559	5.93e-263	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_00560	7.17e-152	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HEOCKMHB_00561	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEOCKMHB_00562	2.76e-221	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEOCKMHB_00563	2.08e-179	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOCKMHB_00564	7.49e-161	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEOCKMHB_00565	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_00566	3.67e-123	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HEOCKMHB_00567	4.54e-303	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HEOCKMHB_00569	7.93e-306	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HEOCKMHB_00570	3.53e-69	tnrA	-	-	K	-	-	-	transcriptional
HEOCKMHB_00571	2.24e-23	-	-	-	-	-	-	-	-
HEOCKMHB_00572	3.57e-35	ykoL	-	-	-	-	-	-	-
HEOCKMHB_00573	3.16e-104	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEOCKMHB_00574	2.57e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HEOCKMHB_00575	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HEOCKMHB_00576	1.82e-197	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEOCKMHB_00577	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HEOCKMHB_00578	1.21e-123	ykoX	-	-	S	-	-	-	membrane-associated protein
HEOCKMHB_00579	5.75e-164	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEOCKMHB_00580	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_00581	3.51e-221	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HEOCKMHB_00582	3.31e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HEOCKMHB_00583	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HEOCKMHB_00584	1.74e-197	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HEOCKMHB_00585	7.83e-301	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HEOCKMHB_00586	2.76e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEOCKMHB_00587	1.37e-26	ykzE	-	-	-	-	-	-	-
HEOCKMHB_00588	1.59e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEOCKMHB_00589	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_00590	9.18e-105	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEOCKMHB_00592	1.59e-244	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEOCKMHB_00593	9.79e-278	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEOCKMHB_00594	1.03e-175	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEOCKMHB_00595	1.52e-283	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEOCKMHB_00596	4.16e-284	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEOCKMHB_00597	1.45e-169	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEOCKMHB_00598	1.15e-140	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEOCKMHB_00599	7.7e-117	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEOCKMHB_00601	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEOCKMHB_00602	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEOCKMHB_00603	2.49e-160	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEOCKMHB_00604	2.96e-176	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEOCKMHB_00605	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HEOCKMHB_00606	6.18e-222	ykvI	-	-	S	-	-	-	membrane
HEOCKMHB_00608	1.81e-196	-	-	-	-	-	-	-	-
HEOCKMHB_00609	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEOCKMHB_00610	2.55e-102	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HEOCKMHB_00611	1.98e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEOCKMHB_00612	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEOCKMHB_00613	6.76e-56	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HEOCKMHB_00614	1.56e-34	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00615	8.76e-38	-	-	-	-	-	-	-	-
HEOCKMHB_00616	5.23e-136	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HEOCKMHB_00617	1.16e-300	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_00618	1.04e-105	stoA	-	-	CO	-	-	-	thiol-disulfide
HEOCKMHB_00619	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEOCKMHB_00620	1.51e-259	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEOCKMHB_00621	4.21e-217	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_00622	1.54e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HEOCKMHB_00623	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_00624	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HEOCKMHB_00625	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEOCKMHB_00626	1.22e-48	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00627	2.29e-252	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HEOCKMHB_00628	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEOCKMHB_00629	5.71e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEOCKMHB_00630	9.19e-65	-	-	-	-	-	-	-	-
HEOCKMHB_00631	1.7e-167	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HEOCKMHB_00632	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEOCKMHB_00633	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_00634	5.43e-274	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEOCKMHB_00635	2.22e-15	-	-	-	-	-	-	-	-
HEOCKMHB_00636	1.3e-211	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HEOCKMHB_00637	1.45e-107	ykyB	-	-	S	-	-	-	YkyB-like protein
HEOCKMHB_00638	2e-302	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_00639	3.48e-114	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00640	7.29e-188	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HEOCKMHB_00641	1.33e-175	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_00643	1.74e-293	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HEOCKMHB_00644	2.11e-49	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00645	6.94e-117	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HEOCKMHB_00646	2.63e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HEOCKMHB_00647	7.03e-98	ykuL	-	-	S	-	-	-	CBS domain
HEOCKMHB_00648	1.08e-214	ccpC	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_00649	2.92e-113	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEOCKMHB_00650	1.07e-207	ykuO	-	-	-	-	-	-	-
HEOCKMHB_00651	2.61e-95	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEOCKMHB_00652	4.79e-128	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEOCKMHB_00653	8.58e-271	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEOCKMHB_00654	1.25e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HEOCKMHB_00655	5.77e-177	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HEOCKMHB_00657	7.8e-23	ykuV	-	-	CO	-	-	-	thiol-disulfide
HEOCKMHB_00658	1.14e-58	ykuV	-	-	CO	-	-	-	thiol-disulfide
HEOCKMHB_00660	3.55e-125	rok	-	-	K	-	-	-	Repressor of ComK
HEOCKMHB_00661	8.39e-201	yknT	-	-	-	ko:K06437	-	ko00000	-
HEOCKMHB_00662	3.85e-130	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEOCKMHB_00663	1.45e-233	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEOCKMHB_00664	7.3e-305	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HEOCKMHB_00665	3.06e-111	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HEOCKMHB_00666	1.19e-107	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HEOCKMHB_00667	4.7e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEOCKMHB_00668	5.77e-134	yknW	-	-	S	-	-	-	Yip1 domain
HEOCKMHB_00669	7e-224	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEOCKMHB_00670	3.39e-157	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_00671	4.52e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEOCKMHB_00672	8.9e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00673	8.8e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HEOCKMHB_00674	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEOCKMHB_00675	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEOCKMHB_00676	3.54e-48	ykoA	-	-	-	-	-	-	-
HEOCKMHB_00677	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOCKMHB_00678	4.63e-200	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEOCKMHB_00679	1.63e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEOCKMHB_00680	7.7e-19	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HEOCKMHB_00681	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HEOCKMHB_00682	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HEOCKMHB_00683	9.16e-301	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEOCKMHB_00684	3.99e-192	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HEOCKMHB_00685	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEOCKMHB_00686	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEOCKMHB_00687	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEOCKMHB_00688	7.4e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HEOCKMHB_00689	3.14e-180	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEOCKMHB_00690	1.49e-126	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEOCKMHB_00691	1.04e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEOCKMHB_00692	9.3e-84	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HEOCKMHB_00693	1.04e-249	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOCKMHB_00694	5.84e-226	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOCKMHB_00695	6.09e-294	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOCKMHB_00696	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOCKMHB_00697	6.84e-60	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HEOCKMHB_00698	3.33e-173	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEOCKMHB_00699	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HEOCKMHB_00700	5.44e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HEOCKMHB_00701	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HEOCKMHB_00702	7.89e-32	ykzI	-	-	-	-	-	-	-
HEOCKMHB_00703	1.57e-193	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HEOCKMHB_00704	1.08e-92	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HEOCKMHB_00705	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HEOCKMHB_00706	9.3e-32	ylaA	-	-	-	-	-	-	-
HEOCKMHB_00708	1.97e-52	ylaE	-	-	-	-	-	-	-
HEOCKMHB_00709	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HEOCKMHB_00710	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HEOCKMHB_00711	1.41e-64	-	-	-	S	-	-	-	YlaH-like protein
HEOCKMHB_00712	7.95e-45	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00713	2.67e-129	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOCKMHB_00714	4.29e-310	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HEOCKMHB_00715	4.45e-104	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEOCKMHB_00716	6.76e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEOCKMHB_00717	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HEOCKMHB_00718	3.73e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEOCKMHB_00719	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEOCKMHB_00720	3.88e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEOCKMHB_00721	2.95e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEOCKMHB_00722	1.61e-250	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEOCKMHB_00723	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEOCKMHB_00724	3.43e-141	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEOCKMHB_00725	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEOCKMHB_00726	1.35e-207	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HEOCKMHB_00727	8.01e-77	ylbA	-	-	S	-	-	-	YugN-like family
HEOCKMHB_00728	1.31e-93	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HEOCKMHB_00729	5.8e-248	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HEOCKMHB_00730	5.5e-83	ylbD	-	-	S	-	-	-	Putative coat protein
HEOCKMHB_00731	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HEOCKMHB_00732	3.73e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HEOCKMHB_00733	4.62e-56	ylbG	-	-	S	-	-	-	UPF0298 protein
HEOCKMHB_00734	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HEOCKMHB_00735	2.38e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEOCKMHB_00736	1.06e-263	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HEOCKMHB_00737	2.03e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEOCKMHB_00738	7.74e-234	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HEOCKMHB_00739	1.26e-281	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEOCKMHB_00740	4.69e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HEOCKMHB_00741	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HEOCKMHB_00742	1.65e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEOCKMHB_00743	2.68e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HEOCKMHB_00744	2.11e-188	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEOCKMHB_00745	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEOCKMHB_00746	9.07e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HEOCKMHB_00747	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEOCKMHB_00748	2.81e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
HEOCKMHB_00749	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEOCKMHB_00750	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HEOCKMHB_00751	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEOCKMHB_00752	2.36e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEOCKMHB_00753	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEOCKMHB_00754	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEOCKMHB_00755	9.42e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEOCKMHB_00756	3.07e-210	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HEOCKMHB_00757	3.74e-170	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEOCKMHB_00758	3.7e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEOCKMHB_00759	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEOCKMHB_00760	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HEOCKMHB_00761	2.17e-213	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEOCKMHB_00762	3.64e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_00763	3.8e-178	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_00764	2.58e-183	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEOCKMHB_00765	1.67e-308	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HEOCKMHB_00766	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HEOCKMHB_00767	3.85e-196	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HEOCKMHB_00768	6.55e-155	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEOCKMHB_00769	6.01e-81	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEOCKMHB_00770	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HEOCKMHB_00771	3.8e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HEOCKMHB_00772	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HEOCKMHB_00773	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEOCKMHB_00774	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEOCKMHB_00775	8.42e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEOCKMHB_00776	7.29e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEOCKMHB_00777	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEOCKMHB_00778	8.98e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HEOCKMHB_00779	4.15e-204	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HEOCKMHB_00780	1.67e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEOCKMHB_00781	4.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEOCKMHB_00782	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HEOCKMHB_00783	2.68e-176	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEOCKMHB_00784	1.17e-218	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEOCKMHB_00785	2.37e-159	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEOCKMHB_00786	3.5e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEOCKMHB_00788	7.81e-178	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HEOCKMHB_00789	5.26e-223	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HEOCKMHB_00790	5.92e-282	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HEOCKMHB_00791	1.31e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HEOCKMHB_00792	7.4e-179	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEOCKMHB_00793	1.13e-175	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HEOCKMHB_00794	1.85e-98	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HEOCKMHB_00795	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HEOCKMHB_00796	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HEOCKMHB_00797	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HEOCKMHB_00798	8e-194	yloC	-	-	S	-	-	-	stress-induced protein
HEOCKMHB_00799	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HEOCKMHB_00800	1.16e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HEOCKMHB_00801	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEOCKMHB_00802	2e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEOCKMHB_00803	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEOCKMHB_00804	1.61e-107	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEOCKMHB_00805	6.66e-215	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEOCKMHB_00806	6.91e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEOCKMHB_00807	7.22e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEOCKMHB_00808	4.92e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HEOCKMHB_00809	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEOCKMHB_00810	6.97e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEOCKMHB_00811	4.85e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HEOCKMHB_00812	5.45e-146	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HEOCKMHB_00813	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HEOCKMHB_00814	6.07e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_00815	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HEOCKMHB_00816	1.69e-152	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEOCKMHB_00817	3.97e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEOCKMHB_00818	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEOCKMHB_00819	2.96e-119	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEOCKMHB_00820	2.58e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEOCKMHB_00821	2.08e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEOCKMHB_00822	5.81e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEOCKMHB_00823	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEOCKMHB_00824	2.48e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEOCKMHB_00825	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HEOCKMHB_00826	2.09e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEOCKMHB_00827	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEOCKMHB_00828	2e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEOCKMHB_00829	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HEOCKMHB_00830	4.9e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HEOCKMHB_00831	5.66e-79	ylqD	-	-	S	-	-	-	YlqD protein
HEOCKMHB_00832	4.17e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEOCKMHB_00833	2.22e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HEOCKMHB_00834	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEOCKMHB_00835	5.95e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEOCKMHB_00836	1.87e-171	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEOCKMHB_00837	0.0	ylqG	-	-	-	-	-	-	-
HEOCKMHB_00838	6.68e-57	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HEOCKMHB_00839	1.66e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEOCKMHB_00840	2.17e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEOCKMHB_00841	6.19e-208	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HEOCKMHB_00842	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEOCKMHB_00843	1.23e-310	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEOCKMHB_00844	1.42e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HEOCKMHB_00845	1.43e-118	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEOCKMHB_00846	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEOCKMHB_00847	4.59e-174	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEOCKMHB_00848	3.14e-81	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEOCKMHB_00849	1.46e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HEOCKMHB_00850	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HEOCKMHB_00851	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HEOCKMHB_00852	3.52e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOCKMHB_00853	6.92e-116	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HEOCKMHB_00854	2.02e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEOCKMHB_00855	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HEOCKMHB_00856	3.78e-76	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HEOCKMHB_00857	7.87e-242	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HEOCKMHB_00858	2.43e-90	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HEOCKMHB_00859	2.56e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HEOCKMHB_00860	3.66e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HEOCKMHB_00861	1.28e-228	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOCKMHB_00862	9.42e-231	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEOCKMHB_00863	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HEOCKMHB_00864	6.3e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HEOCKMHB_00865	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HEOCKMHB_00866	9.02e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HEOCKMHB_00867	4.51e-165	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HEOCKMHB_00868	3.29e-238	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOCKMHB_00869	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEOCKMHB_00870	4.59e-210	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HEOCKMHB_00871	1.43e-196	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HEOCKMHB_00872	5.21e-222	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEOCKMHB_00873	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HEOCKMHB_00874	1.01e-104	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HEOCKMHB_00875	1.39e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEOCKMHB_00876	6.74e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEOCKMHB_00877	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_00878	2.54e-84	ylxL	-	-	-	-	-	-	-
HEOCKMHB_00879	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HEOCKMHB_00880	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEOCKMHB_00881	2.03e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HEOCKMHB_00882	1.59e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEOCKMHB_00883	2.49e-183	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEOCKMHB_00884	1.48e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HEOCKMHB_00885	8.59e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEOCKMHB_00886	2.58e-293	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HEOCKMHB_00887	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEOCKMHB_00888	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEOCKMHB_00889	9.4e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HEOCKMHB_00890	1.35e-262	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HEOCKMHB_00891	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HEOCKMHB_00892	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HEOCKMHB_00893	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEOCKMHB_00894	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HEOCKMHB_00895	2.38e-67	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEOCKMHB_00896	2.64e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEOCKMHB_00897	6.31e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEOCKMHB_00898	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEOCKMHB_00899	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEOCKMHB_00900	2.3e-229	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HEOCKMHB_00901	9.79e-298	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HEOCKMHB_00902	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HEOCKMHB_00903	4.32e-202	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HEOCKMHB_00904	6.97e-131	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEOCKMHB_00905	5.33e-244	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEOCKMHB_00906	3.69e-278	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEOCKMHB_00907	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEOCKMHB_00908	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEOCKMHB_00909	5.34e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HEOCKMHB_00910	7.4e-41	-	-	-	S	-	-	-	YlzJ-like protein
HEOCKMHB_00911	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEOCKMHB_00912	1.38e-166	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_00913	2.76e-290	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_00914	7.8e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_00915	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HEOCKMHB_00916	1.64e-299	albE	-	-	S	-	-	-	Peptidase M16
HEOCKMHB_00917	1.71e-302	ymfH	-	-	S	-	-	-	zinc protease
HEOCKMHB_00918	1.13e-161	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEOCKMHB_00919	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEOCKMHB_00920	3.66e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HEOCKMHB_00921	2.26e-166	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HEOCKMHB_00922	2.75e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEOCKMHB_00923	2.57e-291	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HEOCKMHB_00924	8.4e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEOCKMHB_00925	4.31e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
HEOCKMHB_00926	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HEOCKMHB_00927	3.06e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HEOCKMHB_00928	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HEOCKMHB_00929	1.32e-247	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEOCKMHB_00930	2.28e-270	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEOCKMHB_00931	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEOCKMHB_00932	2.37e-85	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HEOCKMHB_00933	3.93e-116	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HEOCKMHB_00934	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEOCKMHB_00935	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEOCKMHB_00936	3.58e-160	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HEOCKMHB_00937	1.77e-202	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEOCKMHB_00938	9.59e-220	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HEOCKMHB_00939	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEOCKMHB_00940	6.16e-48	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HEOCKMHB_00941	9.98e-307	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HEOCKMHB_00942	7.4e-179	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HEOCKMHB_00943	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HEOCKMHB_00944	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEOCKMHB_00945	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEOCKMHB_00946	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEOCKMHB_00947	2.17e-141	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEOCKMHB_00948	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEOCKMHB_00949	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HEOCKMHB_00950	4.53e-283	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEOCKMHB_00951	3e-93	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEOCKMHB_00952	3.52e-149	yoaK	-	-	S	-	-	-	Membrane
HEOCKMHB_00953	9.32e-81	ymzB	-	-	-	-	-	-	-
HEOCKMHB_00954	9.4e-317	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HEOCKMHB_00955	2.64e-07	-	-	-	-	-	-	-	-
HEOCKMHB_00956	3.08e-151	ymaC	-	-	S	-	-	-	Replication protein
HEOCKMHB_00957	9.17e-100	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HEOCKMHB_00958	1.76e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEOCKMHB_00959	1.17e-62	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEOCKMHB_00961	9.08e-72	ymaF	-	-	S	-	-	-	YmaF family
HEOCKMHB_00962	7.19e-210	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEOCKMHB_00963	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEOCKMHB_00964	1.87e-53	-	-	-	-	-	-	-	-
HEOCKMHB_00965	2.31e-29	ymzA	-	-	-	-	-	-	-
HEOCKMHB_00966	4.43e-77	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HEOCKMHB_00967	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOCKMHB_00968	5.94e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEOCKMHB_00969	2.21e-132	ymaB	-	-	S	-	-	-	MutT family
HEOCKMHB_00970	3.91e-05	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_00971	2e-112	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_00972	2.58e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HEOCKMHB_00973	9.64e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEOCKMHB_00974	5.35e-307	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEOCKMHB_00975	8.18e-86	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HEOCKMHB_00976	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HEOCKMHB_00977	1.1e-192	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEOCKMHB_00979	1.36e-111	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HEOCKMHB_00980	7.74e-121	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HEOCKMHB_00981	1.82e-187	-	-	-	V	-	-	-	HNH endonuclease
HEOCKMHB_00982	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEOCKMHB_00983	3.18e-67	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HEOCKMHB_00985	2.08e-162	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HEOCKMHB_00986	2.1e-52	-	-	-	S	-	-	-	YolD-like protein
HEOCKMHB_00987	8.79e-283	dinB2	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOCKMHB_00988	5.27e-79	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HEOCKMHB_00989	1.08e-59	cmoA	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
HEOCKMHB_00990	9.95e-38	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_00991	2.54e-265	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HEOCKMHB_00992	4.44e-150	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HEOCKMHB_00993	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HEOCKMHB_00994	7.81e-116	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HEOCKMHB_00995	3.77e-225	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HEOCKMHB_00997	7.33e-250	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEOCKMHB_00998	0.000425	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEOCKMHB_00999	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HEOCKMHB_01000	4.77e-203	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOCKMHB_01001	1.6e-13	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOCKMHB_01002	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOCKMHB_01003	6.3e-36	yoaF	-	-	-	-	-	-	-
HEOCKMHB_01005	6.83e-121	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_01006	1.52e-38	-	-	-	-	-	-	-	-
HEOCKMHB_01009	2.04e-68	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HEOCKMHB_01010	3.62e-155	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEOCKMHB_01011	1.44e-110	yobS	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01012	1.22e-159	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEOCKMHB_01013	1.29e-117	yobW	-	-	-	-	-	-	-
HEOCKMHB_01014	3.14e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HEOCKMHB_01015	5.45e-154	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEOCKMHB_01016	5.42e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HEOCKMHB_01017	9.94e-172	-	-	-	J	-	-	-	Protein required for attachment to host cells
HEOCKMHB_01018	2.99e-119	yocC	-	-	-	-	-	-	-
HEOCKMHB_01019	8.07e-233	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HEOCKMHB_01021	6.61e-157	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HEOCKMHB_01022	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEOCKMHB_01024	2.71e-143	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOCKMHB_01025	7.44e-78	yocK	-	-	T	-	-	-	general stress protein
HEOCKMHB_01027	1.16e-11	yocN	-	-	-	-	-	-	-
HEOCKMHB_01028	2.21e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEOCKMHB_01029	8.77e-41	yozN	-	-	-	-	-	-	-
HEOCKMHB_01030	1.83e-49	yocN	-	-	-	-	-	-	-
HEOCKMHB_01031	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HEOCKMHB_01033	4.69e-43	yozC	-	-	-	-	-	-	-
HEOCKMHB_01034	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEOCKMHB_01035	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HEOCKMHB_01036	5.12e-207	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HEOCKMHB_01037	8.96e-293	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEOCKMHB_01038	3.02e-209	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HEOCKMHB_01039	8.69e-156	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEOCKMHB_01040	1.12e-257	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEOCKMHB_01041	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEOCKMHB_01042	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HEOCKMHB_01043	2e-207	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HEOCKMHB_01044	1.31e-135	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEOCKMHB_01045	6.37e-207	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEOCKMHB_01046	1.18e-43	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEOCKMHB_01047	6.89e-278	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HEOCKMHB_01048	3.97e-136	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEOCKMHB_01050	1.51e-297	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HEOCKMHB_01051	6.24e-187	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOCKMHB_01052	2.61e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HEOCKMHB_01053	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HEOCKMHB_01054	3.66e-31	-	-	-	-	-	-	-	-
HEOCKMHB_01055	3.04e-203	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HEOCKMHB_01056	1.83e-101	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HEOCKMHB_01058	9.37e-83	iolK	-	-	S	-	-	-	tautomerase
HEOCKMHB_01059	1.93e-69	yodB	-	-	K	-	-	-	transcriptional
HEOCKMHB_01060	6.14e-135	yodC	-	-	C	-	-	-	nitroreductase
HEOCKMHB_01061	1.12e-118	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HEOCKMHB_01062	8.81e-212	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEOCKMHB_01063	1.14e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEOCKMHB_01064	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOCKMHB_01065	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HEOCKMHB_01066	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEOCKMHB_01067	3.79e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_01068	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEOCKMHB_01069	1.3e-123	yodH	-	-	Q	-	-	-	Methyltransferase
HEOCKMHB_01070	2.3e-30	yodI	-	-	-	-	-	-	-
HEOCKMHB_01071	8.69e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HEOCKMHB_01072	4.29e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HEOCKMHB_01074	1.16e-72	yodL	-	-	S	-	-	-	YodL-like
HEOCKMHB_01075	8.36e-131	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HEOCKMHB_01076	1.97e-33	yozD	-	-	S	-	-	-	YozD-like protein
HEOCKMHB_01078	1.18e-155	yodN	-	-	-	-	-	-	-
HEOCKMHB_01079	1.39e-66	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_01080	2.87e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HEOCKMHB_01081	6.45e-59	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HEOCKMHB_01082	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HEOCKMHB_01083	4.82e-180	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HEOCKMHB_01084	4.03e-315	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HEOCKMHB_01085	8.26e-154	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEOCKMHB_01086	5.2e-156	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEOCKMHB_01087	2.06e-297	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOCKMHB_01089	3.54e-83	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HEOCKMHB_01091	3.96e-176	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HEOCKMHB_01092	1.17e-286	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HEOCKMHB_01093	2.84e-54	cgeC	-	-	-	ko:K06321	-	ko00000	-
HEOCKMHB_01094	1.08e-81	cgeA	-	-	-	ko:K06319	-	ko00000	-
HEOCKMHB_01095	6.45e-215	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HEOCKMHB_01096	7.88e-267	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HEOCKMHB_01097	5.78e-91	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEOCKMHB_01100	5.97e-151	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
HEOCKMHB_01102	6.05e-22	-	-	-	S	-	-	-	Regulatory protein YrvL
HEOCKMHB_01103	6.94e-262	yokA	-	-	L	-	-	-	Recombinase
HEOCKMHB_01104	1.29e-129	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEOCKMHB_01105	2.47e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HEOCKMHB_01106	1.34e-130	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEOCKMHB_01107	3.91e-88	ypoP	-	-	K	-	-	-	transcriptional
HEOCKMHB_01108	2.45e-122	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_01109	3.62e-167	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEOCKMHB_01110	2.24e-131	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEOCKMHB_01111	3.66e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HEOCKMHB_01112	7.88e-305	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEOCKMHB_01113	1.54e-207	yplP	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01114	7.14e-141	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HEOCKMHB_01115	9.83e-141	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEOCKMHB_01116	6.3e-110	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEOCKMHB_01117	2.08e-202	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEOCKMHB_01118	1.41e-142	ypjP	-	-	S	-	-	-	YpjP-like protein
HEOCKMHB_01119	2.63e-167	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HEOCKMHB_01120	1.38e-98	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HEOCKMHB_01121	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HEOCKMHB_01122	8.12e-197	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEOCKMHB_01123	1.69e-116	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEOCKMHB_01124	4.95e-107	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HEOCKMHB_01126	1.56e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEOCKMHB_01127	1.01e-272	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEOCKMHB_01128	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HEOCKMHB_01129	4.27e-16	degR	-	-	-	-	-	-	-
HEOCKMHB_01130	5.37e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HEOCKMHB_01131	6.37e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
HEOCKMHB_01132	4.29e-152	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HEOCKMHB_01133	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEOCKMHB_01134	3.51e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HEOCKMHB_01136	2.07e-204	ypcP	-	-	L	-	-	-	5'3' exonuclease
HEOCKMHB_01137	5.97e-11	-	-	-	-	-	-	-	-
HEOCKMHB_01138	3e-45	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HEOCKMHB_01139	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HEOCKMHB_01140	2.25e-111	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HEOCKMHB_01141	3.81e-254	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HEOCKMHB_01142	2.22e-130	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_01143	8.02e-60	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HEOCKMHB_01144	2.2e-09	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEOCKMHB_01145	4.64e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HEOCKMHB_01146	8.76e-124	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEOCKMHB_01147	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEOCKMHB_01148	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HEOCKMHB_01150	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HEOCKMHB_01151	2.19e-96	yqgA	-	-	-	-	-	-	-
HEOCKMHB_01152	3.07e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HEOCKMHB_01153	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEOCKMHB_01154	3.67e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HEOCKMHB_01155	5.48e-36	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HEOCKMHB_01157	3.33e-285	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HEOCKMHB_01158	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEOCKMHB_01159	6.99e-115	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HEOCKMHB_01160	5.45e-79	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEOCKMHB_01161	2.64e-59	yppG	-	-	S	-	-	-	YppG-like protein
HEOCKMHB_01166	1.05e-225	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HEOCKMHB_01167	8.49e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEOCKMHB_01168	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEOCKMHB_01169	4.6e-113	ypoC	-	-	-	-	-	-	-
HEOCKMHB_01170	1.63e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEOCKMHB_01171	8.05e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HEOCKMHB_01172	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HEOCKMHB_01173	1.1e-278	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEOCKMHB_01174	2.74e-95	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_01175	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HEOCKMHB_01176	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HEOCKMHB_01177	1.98e-83	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEOCKMHB_01178	4.82e-194	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEOCKMHB_01179	1.89e-191	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEOCKMHB_01180	2.04e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEOCKMHB_01181	1.53e-266	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEOCKMHB_01182	7.01e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEOCKMHB_01183	3.8e-162	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HEOCKMHB_01184	3.58e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HEOCKMHB_01185	9.38e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEOCKMHB_01186	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HEOCKMHB_01187	6.13e-199	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_01188	5.93e-282	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEOCKMHB_01189	1.09e-177	ypjB	-	-	S	-	-	-	sporulation protein
HEOCKMHB_01190	1.01e-124	ypjA	-	-	S	-	-	-	membrane
HEOCKMHB_01191	9.48e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HEOCKMHB_01192	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HEOCKMHB_01193	2.27e-124	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HEOCKMHB_01194	1.21e-94	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HEOCKMHB_01195	2.14e-128	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HEOCKMHB_01196	7.68e-292	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEOCKMHB_01197	3.79e-290	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEOCKMHB_01198	9.38e-256	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HEOCKMHB_01199	2.67e-251	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEOCKMHB_01200	1.08e-175	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEOCKMHB_01201	9.2e-286	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEOCKMHB_01202	2.57e-141	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HEOCKMHB_01203	1.15e-158	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HEOCKMHB_01204	3.8e-201	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEOCKMHB_01205	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEOCKMHB_01206	8.09e-77	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEOCKMHB_01207	1.14e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEOCKMHB_01208	3.26e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEOCKMHB_01209	9.33e-177	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HEOCKMHB_01210	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEOCKMHB_01211	5.39e-250	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEOCKMHB_01212	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEOCKMHB_01213	2.68e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEOCKMHB_01214	6.23e-47	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEOCKMHB_01215	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HEOCKMHB_01216	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEOCKMHB_01217	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEOCKMHB_01219	2.47e-166	yphF	-	-	-	-	-	-	-
HEOCKMHB_01220	1.13e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HEOCKMHB_01221	9.14e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HEOCKMHB_01222	2.86e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HEOCKMHB_01223	6.38e-129	yphA	-	-	-	-	-	-	-
HEOCKMHB_01224	1.32e-12	-	-	-	S	-	-	-	YpzI-like protein
HEOCKMHB_01225	4.76e-228	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEOCKMHB_01226	3.17e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HEOCKMHB_01227	3.75e-142	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HEOCKMHB_01228	1.12e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HEOCKMHB_01229	6.58e-72	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HEOCKMHB_01230	1.1e-311	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HEOCKMHB_01231	2.15e-203	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HEOCKMHB_01232	2.61e-155	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HEOCKMHB_01233	5.93e-236	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HEOCKMHB_01234	8.6e-310	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEOCKMHB_01235	7.9e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEOCKMHB_01236	5.62e-181	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HEOCKMHB_01237	3.73e-109	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HEOCKMHB_01238	8.85e-110	ypbE	-	-	M	-	-	-	Lysin motif
HEOCKMHB_01239	1.84e-123	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HEOCKMHB_01240	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEOCKMHB_01241	2.97e-244	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HEOCKMHB_01242	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HEOCKMHB_01243	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEOCKMHB_01244	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOCKMHB_01245	6.63e-216	rsiX	-	-	-	-	-	-	-
HEOCKMHB_01246	3.09e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_01247	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_01248	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_01249	3.09e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEOCKMHB_01250	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HEOCKMHB_01251	9.77e-125	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEOCKMHB_01252	1.74e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEOCKMHB_01253	7.39e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HEOCKMHB_01254	6.22e-134	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HEOCKMHB_01255	2.36e-268	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEOCKMHB_01256	5.9e-107	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HEOCKMHB_01257	1.3e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEOCKMHB_01258	4.93e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEOCKMHB_01260	2.41e-113	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HEOCKMHB_01261	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOCKMHB_01262	1.4e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEOCKMHB_01263	8.2e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEOCKMHB_01264	3.81e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HEOCKMHB_01265	1.24e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEOCKMHB_01266	7.86e-68	ypuD	-	-	-	-	-	-	-
HEOCKMHB_01267	8.88e-122	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEOCKMHB_01268	6.23e-102	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HEOCKMHB_01269	1.18e-103	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEOCKMHB_01270	3.35e-194	ypuA	-	-	S	-	-	-	Secreted protein
HEOCKMHB_01271	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEOCKMHB_01272	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HEOCKMHB_01273	1.2e-138	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEOCKMHB_01274	3.57e-74	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEOCKMHB_01275	9.17e-241	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HEOCKMHB_01276	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HEOCKMHB_01277	9.1e-141	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HEOCKMHB_01278	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_01279	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEOCKMHB_01280	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HEOCKMHB_01281	5.58e-270	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEOCKMHB_01282	8.69e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEOCKMHB_01283	4.39e-288	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEOCKMHB_01284	1.78e-210	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HEOCKMHB_01285	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HEOCKMHB_01286	3.08e-102	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HEOCKMHB_01287	4.12e-141	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEOCKMHB_01288	2.87e-43	yqkK	-	-	-	-	-	-	-
HEOCKMHB_01289	5.05e-33	-	-	-	-	-	-	-	-
HEOCKMHB_01290	9.28e-307	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEOCKMHB_01291	3.56e-313	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEOCKMHB_01292	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HEOCKMHB_01293	4.88e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HEOCKMHB_01294	2.32e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01295	1.43e-271	yqxK	-	-	L	-	-	-	DNA helicase
HEOCKMHB_01296	1.42e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HEOCKMHB_01297	5.78e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HEOCKMHB_01298	2.34e-211	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEOCKMHB_01299	3.06e-15	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HEOCKMHB_01300	2.33e-170	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEOCKMHB_01301	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HEOCKMHB_01302	1.22e-76	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HEOCKMHB_01303	1.93e-212	yqkA	-	-	K	-	-	-	GrpB protein
HEOCKMHB_01304	1.92e-08	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HEOCKMHB_01305	2.7e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HEOCKMHB_01306	1.01e-293	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOCKMHB_01307	7.27e-73	-	-	-	S	-	-	-	YolD-like protein
HEOCKMHB_01309	7.76e-204	yueF	-	-	S	-	-	-	transporter activity
HEOCKMHB_01311	2.47e-224	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HEOCKMHB_01312	4.1e-307	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HEOCKMHB_01313	2.99e-174	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_01314	1.11e-213	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEOCKMHB_01315	7.56e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOCKMHB_01316	9.08e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HEOCKMHB_01317	2.42e-61	-	-	-	S	-	-	-	GlpM protein
HEOCKMHB_01318	1.64e-120	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEOCKMHB_01319	4.49e-63	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEOCKMHB_01320	2.4e-184	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEOCKMHB_01321	4.44e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEOCKMHB_01322	2.97e-215	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEOCKMHB_01323	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEOCKMHB_01324	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEOCKMHB_01325	7.78e-294	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEOCKMHB_01326	1.36e-36	yqzJ	-	-	-	-	-	-	-
HEOCKMHB_01327	6.56e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEOCKMHB_01328	4.14e-256	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HEOCKMHB_01329	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEOCKMHB_01330	6.09e-92	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HEOCKMHB_01332	3.99e-118	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_01333	1.79e-216	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HEOCKMHB_01334	1.13e-160	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEOCKMHB_01335	7.04e-140	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEOCKMHB_01336	2.18e-170	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEOCKMHB_01337	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HEOCKMHB_01338	3.22e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEOCKMHB_01339	2.69e-265	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOCKMHB_01340	4e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOCKMHB_01341	4.18e-217	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOCKMHB_01342	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOCKMHB_01343	3.86e-260	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HEOCKMHB_01344	5.27e-260	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEOCKMHB_01345	1.53e-191	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HEOCKMHB_01346	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HEOCKMHB_01347	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HEOCKMHB_01348	7.1e-199	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEOCKMHB_01349	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HEOCKMHB_01350	9.85e-261	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEOCKMHB_01351	9.37e-256	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HEOCKMHB_01352	8.59e-59	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HEOCKMHB_01353	1.22e-101	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HEOCKMHB_01354	1.21e-266	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEOCKMHB_01355	1.04e-163	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEOCKMHB_01356	1.94e-127	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HEOCKMHB_01358	2.52e-119	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEOCKMHB_01359	3.85e-144	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HEOCKMHB_01361	2.85e-266	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEOCKMHB_01364	4.31e-260	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEOCKMHB_01365	4.13e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEOCKMHB_01366	9.07e-297	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HEOCKMHB_01367	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HEOCKMHB_01368	1.03e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEOCKMHB_01369	2.69e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HEOCKMHB_01370	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEOCKMHB_01371	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEOCKMHB_01372	4.44e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEOCKMHB_01373	5.36e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEOCKMHB_01374	2.51e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEOCKMHB_01375	2.58e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEOCKMHB_01376	5.53e-87	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_01377	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEOCKMHB_01378	2.59e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEOCKMHB_01379	1.88e-86	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HEOCKMHB_01380	1.3e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HEOCKMHB_01381	1.74e-129	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HEOCKMHB_01382	3.02e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HEOCKMHB_01383	5.28e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HEOCKMHB_01384	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HEOCKMHB_01385	2.23e-108	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HEOCKMHB_01386	7.55e-213	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HEOCKMHB_01387	1.64e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HEOCKMHB_01388	9.69e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEOCKMHB_01389	2.75e-245	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEOCKMHB_01390	2.13e-113	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HEOCKMHB_01391	1.12e-215	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HEOCKMHB_01392	8.59e-80	yqhP	-	-	-	-	-	-	-
HEOCKMHB_01393	2.51e-203	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEOCKMHB_01394	1.14e-96	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEOCKMHB_01395	1.25e-201	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEOCKMHB_01396	2.33e-84	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HEOCKMHB_01397	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEOCKMHB_01398	2.14e-313	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEOCKMHB_01399	7.69e-254	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HEOCKMHB_01400	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOCKMHB_01401	8.42e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HEOCKMHB_01402	1.3e-29	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HEOCKMHB_01403	2.27e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HEOCKMHB_01404	8.28e-178	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HEOCKMHB_01405	5.48e-95	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HEOCKMHB_01406	7.32e-144	yqxM	-	-	-	ko:K19433	-	ko00000	-
HEOCKMHB_01407	3.98e-70	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEOCKMHB_01408	9.56e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
HEOCKMHB_01409	8.44e-75	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HEOCKMHB_01410	2.45e-28	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HEOCKMHB_01411	1.56e-26	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HEOCKMHB_01412	3.1e-91	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HEOCKMHB_01413	8.07e-54	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HEOCKMHB_01414	5.79e-227	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HEOCKMHB_01415	5.85e-253	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEOCKMHB_01416	1.34e-231	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HEOCKMHB_01417	2.13e-294	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEOCKMHB_01418	2.41e-175	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOCKMHB_01420	2.15e-82	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HEOCKMHB_01421	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HEOCKMHB_01422	2e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HEOCKMHB_01423	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HEOCKMHB_01424	2.02e-63	dglA	-	-	S	-	-	-	Thiamine-binding protein
HEOCKMHB_01425	1.57e-239	yqgU	-	-	-	-	-	-	-
HEOCKMHB_01426	1.33e-256	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HEOCKMHB_01427	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HEOCKMHB_01428	1.87e-37	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HEOCKMHB_01429	2.58e-269	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEOCKMHB_01430	5.38e-11	yqgO	-	-	-	-	-	-	-
HEOCKMHB_01431	7.01e-116	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEOCKMHB_01432	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEOCKMHB_01433	3.42e-68	yqzD	-	-	-	-	-	-	-
HEOCKMHB_01434	1.97e-96	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOCKMHB_01435	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEOCKMHB_01436	2.99e-179	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEOCKMHB_01437	1.88e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HEOCKMHB_01438	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HEOCKMHB_01439	6.14e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEOCKMHB_01440	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HEOCKMHB_01441	5.94e-283	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HEOCKMHB_01442	8.52e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HEOCKMHB_01443	7.59e-97	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HEOCKMHB_01444	8.5e-165	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HEOCKMHB_01445	5.95e-59	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HEOCKMHB_01446	1.09e-253	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEOCKMHB_01447	3.9e-79	yqfX	-	-	S	-	-	-	membrane
HEOCKMHB_01448	3.23e-139	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HEOCKMHB_01449	2.63e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HEOCKMHB_01450	2.47e-195	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_01451	2.9e-47	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HEOCKMHB_01452	9.16e-209	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEOCKMHB_01453	3.91e-304	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEOCKMHB_01454	7.12e-57	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HEOCKMHB_01455	4.12e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEOCKMHB_01456	2.97e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEOCKMHB_01457	1.65e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HEOCKMHB_01458	7.67e-80	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEOCKMHB_01459	8e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEOCKMHB_01460	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEOCKMHB_01461	4.54e-111	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HEOCKMHB_01462	1.75e-188	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEOCKMHB_01463	3.41e-144	ccpN	-	-	K	-	-	-	CBS domain
HEOCKMHB_01464	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HEOCKMHB_01465	2.03e-220	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HEOCKMHB_01466	1.9e-180	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HEOCKMHB_01467	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HEOCKMHB_01468	2.86e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEOCKMHB_01469	1.92e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEOCKMHB_01470	8.76e-82	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HEOCKMHB_01471	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEOCKMHB_01472	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HEOCKMHB_01473	1.28e-36	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HEOCKMHB_01474	4.78e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HEOCKMHB_01475	3.96e-273	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HEOCKMHB_01476	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HEOCKMHB_01477	2.58e-48	yqfB	-	-	-	-	-	-	-
HEOCKMHB_01478	1.22e-186	yqfA	-	-	S	-	-	-	UPF0365 protein
HEOCKMHB_01479	3.91e-288	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HEOCKMHB_01480	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HEOCKMHB_01481	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HEOCKMHB_01482	1.99e-194	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HEOCKMHB_01483	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HEOCKMHB_01484	3.96e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEOCKMHB_01485	1.27e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HEOCKMHB_01486	6.71e-264	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEOCKMHB_01487	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HEOCKMHB_01488	1.99e-104	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEOCKMHB_01489	1.11e-239	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEOCKMHB_01490	3.95e-274	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HEOCKMHB_01491	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEOCKMHB_01492	2.1e-71	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HEOCKMHB_01493	2.6e-279	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HEOCKMHB_01494	1.02e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEOCKMHB_01495	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HEOCKMHB_01496	6.09e-231	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HEOCKMHB_01497	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEOCKMHB_01498	3.79e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HEOCKMHB_01499	1.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HEOCKMHB_01500	1.14e-190	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOCKMHB_01501	1.98e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
HEOCKMHB_01502	9.39e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEOCKMHB_01503	3.25e-131	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HEOCKMHB_01504	1.38e-138	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEOCKMHB_01505	1.81e-60	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HEOCKMHB_01506	2.83e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEOCKMHB_01507	1.87e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEOCKMHB_01508	5.51e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HEOCKMHB_01510	3.99e-176	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEOCKMHB_01511	3.16e-178	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEOCKMHB_01512	3.41e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_01514	9.72e-08	-	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEOCKMHB_01515	2.47e-274	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HEOCKMHB_01516	6.78e-160	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_01517	1.82e-17	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HEOCKMHB_01518	1.46e-194	-	-	-	L	-	-	-	AAA ATPase domain
HEOCKMHB_01519	1.18e-50	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEOCKMHB_01522	8.84e-200	smvA	-	-	EGP	ko:K08167	-	ko00000,ko00002,ko01504,ko02000	Major facilitator superfamily
HEOCKMHB_01523	2.93e-98	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	TIGRFAM glutamine amidotransferase of anthranilate synthase
HEOCKMHB_01524	1.71e-224	-	4.1.3.27, 4.2.99.21, 5.4.4.2	-	EH	ko:K01657,ko:K04781	ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I domain protein
HEOCKMHB_01525	1.69e-220	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	phenylacetate-CoA ligase activity
HEOCKMHB_01526	0.0	-	-	-	Q	-	-	-	AMP-binding enzyme C-terminal domain
HEOCKMHB_01527	4.19e-152	-	-	-	S	-	-	-	Winged helix DNA-binding domain
HEOCKMHB_01528	5.94e-257	glyA_1	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEOCKMHB_01529	2.82e-142	mchB	-	-	Q	ko:K12240	ko01053,map01053	ko00000,ko00001,ko01008	Thioesterase involved in non-ribosomal peptide biosynthesis
HEOCKMHB_01531	1.28e-206	-	-	-	K	ko:K13572	-	ko00000,ko03051	HTH domain
HEOCKMHB_01532	2.68e-135	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HEOCKMHB_01533	8.14e-25	-	-	-	-	-	-	-	-
HEOCKMHB_01537	5.49e-13	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HEOCKMHB_01539	8.55e-19	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HEOCKMHB_01540	8.03e-141	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEOCKMHB_01541	8.72e-34	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HEOCKMHB_01542	1.23e-174	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Reductase
HEOCKMHB_01543	1.29e-89	-	-	-	K	-	-	-	MerR family transcriptional regulator
HEOCKMHB_01544	6.77e-21	xkdG	-	-	S	-	-	-	Phage capsid family
HEOCKMHB_01545	1.25e-202	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HEOCKMHB_01546	1.02e-79	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEOCKMHB_01547	3.5e-47	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HEOCKMHB_01549	1.84e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
HEOCKMHB_01550	5.34e-280	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_01551	6.08e-105	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HEOCKMHB_01552	2.76e-120	-	-	-	S	-	-	-	DinB family
HEOCKMHB_01554	1.14e-187	supH	-	-	S	-	-	-	hydrolase
HEOCKMHB_01555	5.2e-93	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEOCKMHB_01556	7.33e-67	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEOCKMHB_01557	2.38e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEOCKMHB_01558	9.08e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEOCKMHB_01559	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_01560	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HEOCKMHB_01561	9.54e-229	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HEOCKMHB_01562	1.88e-106	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEOCKMHB_01563	5.33e-211	yybE	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01564	1.32e-270	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_01565	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEOCKMHB_01566	4.77e-130	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HEOCKMHB_01567	3.67e-120	yrhH	-	-	Q	-	-	-	methyltransferase
HEOCKMHB_01568	2.37e-07	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HEOCKMHB_01569	4.62e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HEOCKMHB_01570	1.48e-78	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HEOCKMHB_01571	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEOCKMHB_01572	4.76e-106	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEOCKMHB_01573	1.35e-46	yrhC	-	-	S	-	-	-	YrhC-like protein
HEOCKMHB_01574	7.59e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEOCKMHB_01575	2.28e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HEOCKMHB_01576	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEOCKMHB_01577	1.4e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEOCKMHB_01578	1.78e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HEOCKMHB_01579	8.77e-104	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HEOCKMHB_01580	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HEOCKMHB_01581	1.62e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEOCKMHB_01582	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HEOCKMHB_01583	1.88e-312	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HEOCKMHB_01584	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HEOCKMHB_01585	4.49e-151	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HEOCKMHB_01586	7.74e-257	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEOCKMHB_01587	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HEOCKMHB_01588	2.72e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEOCKMHB_01589	1.1e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HEOCKMHB_01590	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEOCKMHB_01591	4.09e-231	yrrI	-	-	S	-	-	-	AI-2E family transporter
HEOCKMHB_01592	1.43e-164	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEOCKMHB_01593	5.82e-185	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEOCKMHB_01594	4.74e-136	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEOCKMHB_01595	1.41e-134	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEOCKMHB_01596	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HEOCKMHB_01597	8.4e-42	yrzR	-	-	-	-	-	-	-
HEOCKMHB_01598	9e-101	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_01599	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEOCKMHB_01600	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEOCKMHB_01601	8.02e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEOCKMHB_01602	2.35e-266	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEOCKMHB_01603	3.74e-83	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_01604	4.18e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEOCKMHB_01605	1.68e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEOCKMHB_01606	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEOCKMHB_01607	7.9e-306	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HEOCKMHB_01610	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HEOCKMHB_01611	4.07e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEOCKMHB_01612	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEOCKMHB_01613	1.71e-116	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEOCKMHB_01614	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEOCKMHB_01615	7.18e-59	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HEOCKMHB_01616	3.74e-104	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEOCKMHB_01617	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEOCKMHB_01618	2.26e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HEOCKMHB_01619	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_01620	1.16e-133	yrbG	-	-	S	-	-	-	membrane
HEOCKMHB_01621	3.7e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HEOCKMHB_01622	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HEOCKMHB_01623	9.18e-290	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEOCKMHB_01624	7.88e-244	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEOCKMHB_01625	3.4e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HEOCKMHB_01626	6.61e-232	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEOCKMHB_01627	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEOCKMHB_01628	1.16e-118	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HEOCKMHB_01630	8.39e-34	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOCKMHB_01631	1.61e-214	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HEOCKMHB_01632	4.89e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEOCKMHB_01633	1.3e-180	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HEOCKMHB_01634	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HEOCKMHB_01635	8.23e-269	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEOCKMHB_01636	1.49e-115	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HEOCKMHB_01637	4.34e-201	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HEOCKMHB_01638	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HEOCKMHB_01639	2.37e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEOCKMHB_01640	2.87e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HEOCKMHB_01641	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HEOCKMHB_01642	5.78e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HEOCKMHB_01643	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HEOCKMHB_01644	3.7e-199	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HEOCKMHB_01645	2.65e-177	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEOCKMHB_01646	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HEOCKMHB_01647	1.61e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEOCKMHB_01648	3.98e-107	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HEOCKMHB_01649	2.51e-201	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HEOCKMHB_01650	2.91e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HEOCKMHB_01651	1.19e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HEOCKMHB_01652	1.6e-128	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HEOCKMHB_01653	2.51e-192	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HEOCKMHB_01654	1.4e-159	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEOCKMHB_01655	2.79e-293	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEOCKMHB_01656	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEOCKMHB_01657	3.61e-34	-	-	-	-	-	-	-	-
HEOCKMHB_01658	3.17e-234	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEOCKMHB_01659	5.07e-232	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HEOCKMHB_01660	4.08e-306	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEOCKMHB_01661	6.63e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HEOCKMHB_01662	4.99e-176	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEOCKMHB_01663	6.05e-222	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEOCKMHB_01664	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HEOCKMHB_01665	2.79e-311	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEOCKMHB_01666	3.63e-110	ysxD	-	-	-	-	-	-	-
HEOCKMHB_01667	8.88e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HEOCKMHB_01668	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEOCKMHB_01669	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HEOCKMHB_01670	8.92e-291	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEOCKMHB_01671	2.43e-284	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEOCKMHB_01672	6.44e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HEOCKMHB_01673	1.04e-147	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEOCKMHB_01674	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEOCKMHB_01675	2.66e-249	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEOCKMHB_01676	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEOCKMHB_01677	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEOCKMHB_01678	1.45e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEOCKMHB_01679	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEOCKMHB_01684	1.78e-113	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HEOCKMHB_01685	3.07e-129	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEOCKMHB_01686	2.38e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEOCKMHB_01687	1.05e-253	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HEOCKMHB_01688	1.06e-192	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEOCKMHB_01689	7.32e-95	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_01690	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_01691	8.26e-96	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HEOCKMHB_01692	1.77e-188	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEOCKMHB_01693	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEOCKMHB_01694	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HEOCKMHB_01695	9.97e-103	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HEOCKMHB_01696	9.22e-270	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEOCKMHB_01697	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEOCKMHB_01698	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEOCKMHB_01699	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HEOCKMHB_01700	5.59e-224	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HEOCKMHB_01701	5.83e-176	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HEOCKMHB_01702	2.18e-172	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HEOCKMHB_01703	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_01704	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOCKMHB_01705	9.33e-150	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HEOCKMHB_01706	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HEOCKMHB_01707	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEOCKMHB_01708	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HEOCKMHB_01709	2.02e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HEOCKMHB_01710	4.23e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEOCKMHB_01711	1.64e-210	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEOCKMHB_01712	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOCKMHB_01713	1.27e-248	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEOCKMHB_01714	1.94e-165	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEOCKMHB_01715	8.83e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HEOCKMHB_01716	5.97e-244	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HEOCKMHB_01717	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HEOCKMHB_01718	5e-309	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HEOCKMHB_01719	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HEOCKMHB_01720	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HEOCKMHB_01721	1.27e-186	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HEOCKMHB_01722	8.11e-211	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HEOCKMHB_01723	2.69e-312	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HEOCKMHB_01724	2.36e-269	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEOCKMHB_01725	1.33e-175	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HEOCKMHB_01726	2.82e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEOCKMHB_01727	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HEOCKMHB_01728	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HEOCKMHB_01729	4.34e-235	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEOCKMHB_01730	1.52e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HEOCKMHB_01731	4.11e-82	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HEOCKMHB_01732	5.91e-51	ysdA	-	-	S	-	-	-	Membrane
HEOCKMHB_01733	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEOCKMHB_01734	1.95e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HEOCKMHB_01735	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEOCKMHB_01736	1.21e-144	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEOCKMHB_01737	3.04e-64	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HEOCKMHB_01738	8.26e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HEOCKMHB_01739	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_01740	2.22e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HEOCKMHB_01741	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEOCKMHB_01742	6.12e-192	ytxC	-	-	S	-	-	-	YtxC-like family
HEOCKMHB_01743	2.03e-136	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_01744	2.64e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HEOCKMHB_01745	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HEOCKMHB_01746	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEOCKMHB_01747	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEOCKMHB_01748	4.24e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEOCKMHB_01749	7.74e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01750	3.31e-251	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HEOCKMHB_01751	4.68e-198	ytbE	-	-	S	-	-	-	reductase
HEOCKMHB_01752	3.15e-123	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEOCKMHB_01753	4.52e-135	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEOCKMHB_01754	2.14e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEOCKMHB_01755	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEOCKMHB_01756	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HEOCKMHB_01757	2.29e-164	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_01758	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HEOCKMHB_01759	1.54e-307	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HEOCKMHB_01760	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEOCKMHB_01761	1.14e-95	ytwI	-	-	S	-	-	-	membrane
HEOCKMHB_01762	8.18e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HEOCKMHB_01763	1.34e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEOCKMHB_01764	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HEOCKMHB_01765	1.33e-228	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEOCKMHB_01766	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEOCKMHB_01767	2.08e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEOCKMHB_01768	1.92e-283	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEOCKMHB_01769	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEOCKMHB_01770	1.12e-71	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HEOCKMHB_01771	3.08e-113	ytrI	-	-	-	-	-	-	-
HEOCKMHB_01772	1.17e-30	-	-	-	-	-	-	-	-
HEOCKMHB_01773	7.37e-223	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HEOCKMHB_01774	3.44e-60	ytpI	-	-	S	-	-	-	YtpI-like protein
HEOCKMHB_01775	3.87e-303	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HEOCKMHB_01776	2.31e-163	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HEOCKMHB_01777	1.33e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_01779	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HEOCKMHB_01780	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEOCKMHB_01781	1.64e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HEOCKMHB_01782	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEOCKMHB_01783	4.08e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HEOCKMHB_01784	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEOCKMHB_01785	1.37e-99	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HEOCKMHB_01786	3.61e-147	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HEOCKMHB_01787	1.31e-103	yteJ	-	-	S	-	-	-	RDD family
HEOCKMHB_01788	1.88e-227	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HEOCKMHB_01789	1.23e-191	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEOCKMHB_01790	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HEOCKMHB_01791	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEOCKMHB_01792	4.15e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEOCKMHB_01793	1.06e-280	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEOCKMHB_01794	3.99e-259	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEOCKMHB_01795	4.41e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEOCKMHB_01796	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEOCKMHB_01797	3.79e-183	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEOCKMHB_01798	2.22e-137	yttP	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01799	2.38e-109	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HEOCKMHB_01800	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HEOCKMHB_01801	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEOCKMHB_01802	1.22e-272	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEOCKMHB_01805	0.000125	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HEOCKMHB_01807	1.52e-161	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEOCKMHB_01808	6.5e-189	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOCKMHB_01809	1.06e-188	-	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01810	7.21e-154	ygaZ	-	-	E	-	-	-	AzlC protein
HEOCKMHB_01811	7.23e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HEOCKMHB_01812	1.41e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEOCKMHB_01813	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEOCKMHB_01814	3.32e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEOCKMHB_01815	9.68e-138	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HEOCKMHB_01816	1.4e-283	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HEOCKMHB_01817	1.87e-127	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEOCKMHB_01818	2.47e-184	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEOCKMHB_01819	7.72e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HEOCKMHB_01820	1.8e-248	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEOCKMHB_01821	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HEOCKMHB_01822	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HEOCKMHB_01823	2.16e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEOCKMHB_01824	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HEOCKMHB_01825	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEOCKMHB_01826	1.15e-136	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEOCKMHB_01827	1.1e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HEOCKMHB_01828	2.23e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HEOCKMHB_01829	5.33e-98	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HEOCKMHB_01830	8.38e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HEOCKMHB_01831	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
HEOCKMHB_01832	1.43e-287	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEOCKMHB_01833	2.98e-90	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEOCKMHB_01834	1.41e-204	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEOCKMHB_01835	4.34e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEOCKMHB_01836	4.54e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
HEOCKMHB_01837	3.42e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
HEOCKMHB_01838	1.86e-214	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HEOCKMHB_01839	2.86e-198	ytlQ	-	-	-	-	-	-	-
HEOCKMHB_01840	2.04e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEOCKMHB_01841	4.05e-214	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEOCKMHB_01842	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HEOCKMHB_01843	3.89e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEOCKMHB_01844	1.72e-251	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HEOCKMHB_01845	1.92e-149	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEOCKMHB_01846	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HEOCKMHB_01847	4.25e-160	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEOCKMHB_01848	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_01849	2.31e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HEOCKMHB_01850	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HEOCKMHB_01851	3.57e-35	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HEOCKMHB_01852	3.97e-232	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_01853	3.41e-296	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEOCKMHB_01854	6.99e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEOCKMHB_01855	1.37e-182	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEOCKMHB_01856	2.49e-313	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HEOCKMHB_01857	6.31e-96	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_01858	8.6e-69	ytwF	-	-	P	-	-	-	Sulfurtransferase
HEOCKMHB_01859	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HEOCKMHB_01860	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HEOCKMHB_01861	1.79e-172	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEOCKMHB_01862	2.16e-265	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HEOCKMHB_01863	4.62e-130	ywaF	-	-	S	-	-	-	Integral membrane protein
HEOCKMHB_01864	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HEOCKMHB_01865	7.67e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_01866	4.31e-206	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HEOCKMHB_01867	5.19e-157	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_01868	3.54e-258	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HEOCKMHB_01869	7.08e-160	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_01870	1.47e-190	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HEOCKMHB_01871	2.63e-203	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEOCKMHB_01872	1.38e-170	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEOCKMHB_01873	9.08e-202	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_01874	6.32e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HEOCKMHB_01876	2.89e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HEOCKMHB_01877	6.73e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HEOCKMHB_01878	4.07e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HEOCKMHB_01880	2.17e-266	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HEOCKMHB_01881	6.67e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HEOCKMHB_01882	7.46e-80	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEOCKMHB_01883	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_01884	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEOCKMHB_01885	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEOCKMHB_01886	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEOCKMHB_01887	1.65e-51	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HEOCKMHB_01888	6.15e-187	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEOCKMHB_01889	6.07e-228	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEOCKMHB_01890	1.38e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEOCKMHB_01891	3.42e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEOCKMHB_01892	5.86e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HEOCKMHB_01893	1.67e-77	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HEOCKMHB_01894	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEOCKMHB_01896	9.99e-98	ytkA	-	-	S	-	-	-	YtkA-like
HEOCKMHB_01897	5.89e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEOCKMHB_01898	5.71e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HEOCKMHB_01899	4.26e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEOCKMHB_01900	7.13e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HEOCKMHB_01901	6.36e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEOCKMHB_01902	9.63e-230	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEOCKMHB_01903	3.88e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HEOCKMHB_01904	4.21e-265	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEOCKMHB_01905	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEOCKMHB_01906	7.22e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEOCKMHB_01907	2.39e-188	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEOCKMHB_01908	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEOCKMHB_01909	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEOCKMHB_01910	8.57e-160	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEOCKMHB_01911	5.18e-93	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HEOCKMHB_01935	3.49e-183	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEOCKMHB_01936	1.44e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HEOCKMHB_01937	2.69e-158	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HEOCKMHB_01938	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEOCKMHB_01939	2.83e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEOCKMHB_01940	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HEOCKMHB_01941	2.95e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEOCKMHB_01942	1.51e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEOCKMHB_01943	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEOCKMHB_01944	2.61e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEOCKMHB_01945	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HEOCKMHB_01946	9.24e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEOCKMHB_01947	1.24e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEOCKMHB_01948	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEOCKMHB_01949	1.16e-43	-	-	-	L	-	-	-	Arm DNA-binding domain
HEOCKMHB_01950	3.68e-35	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEOCKMHB_01951	4.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HEOCKMHB_01952	8.41e-82	-	-	-	-	-	-	-	-
HEOCKMHB_01953	3.22e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_01954	1.73e-18	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_01955	2.39e-48	-	-	-	-	-	-	-	-
HEOCKMHB_01956	4.76e-76	-	-	-	S	-	-	-	DNA binding
HEOCKMHB_01957	3.27e-110	-	-	-	-	-	-	-	-
HEOCKMHB_01961	2.37e-98	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HEOCKMHB_01962	6.89e-72	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HEOCKMHB_01963	3.37e-162	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HEOCKMHB_01964	4.55e-36	yqaL	-	-	L	-	-	-	DnaD domain protein
HEOCKMHB_01965	1.54e-152	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HEOCKMHB_01967	5.52e-28	-	-	-	S	-	-	-	YopX protein
HEOCKMHB_01968	1.57e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HEOCKMHB_01970	1.16e-23	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEOCKMHB_01973	4.72e-217	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HEOCKMHB_01975	2.08e-54	-	-	-	S	-	-	-	dUTPase
HEOCKMHB_01978	2.62e-08	-	-	-	S	-	-	-	YopX protein
HEOCKMHB_01983	3.27e-63	-	-	-	-	-	-	-	-
HEOCKMHB_01985	1.76e-22	-	-	-	V	-	-	-	VanZ like family
HEOCKMHB_01986	5.88e-88	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOCKMHB_01988	1.74e-17	-	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_01991	7.49e-103	yqaS	-	-	L	-	-	-	DNA packaging
HEOCKMHB_01992	9.66e-225	-	-	-	S	-	-	-	Pfam:Terminase_3C
HEOCKMHB_01993	9.32e-157	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEOCKMHB_01994	1.53e-116	-	-	-	S	-	-	-	Phage Mu protein F like protein
HEOCKMHB_01996	3.82e-56	-	-	-	S	-	-	-	Phage minor structural protein GP20
HEOCKMHB_01997	1.85e-61	-	-	-	S	-	-	-	viral capsid
HEOCKMHB_02000	2.05e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEOCKMHB_02001	7.37e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
HEOCKMHB_02002	1.29e-49	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEOCKMHB_02003	1.14e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
HEOCKMHB_02004	3.23e-44	-	-	-	S	-	-	-	Phage tail tube protein
HEOCKMHB_02006	3.59e-186	-	-	-	-	-	-	-	-
HEOCKMHB_02008	2.51e-246	-	-	-	L	-	-	-	Phage minor structural protein
HEOCKMHB_02012	1.19e-40	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HEOCKMHB_02013	2.07e-37	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEOCKMHB_02014	2e-155	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEOCKMHB_02017	0.0	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HEOCKMHB_02019	2.21e-81	-	-	-	-	-	-	-	-
HEOCKMHB_02020	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HEOCKMHB_02021	1.55e-251	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HEOCKMHB_02022	9.02e-311	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HEOCKMHB_02023	4.48e-211	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HEOCKMHB_02024	1.47e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HEOCKMHB_02025	4.36e-143	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HEOCKMHB_02026	6.45e-222	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEOCKMHB_02027	3.97e-156	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HEOCKMHB_02028	4.64e-200	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HEOCKMHB_02029	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HEOCKMHB_02030	5.52e-184	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HEOCKMHB_02031	1.08e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_02032	7.9e-246	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HEOCKMHB_02033	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HEOCKMHB_02034	1.51e-189	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HEOCKMHB_02036	9.6e-47	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HEOCKMHB_02037	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HEOCKMHB_02038	2.56e-307	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_02039	7.59e-180	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOCKMHB_02040	7.99e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HEOCKMHB_02041	1e-254	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEOCKMHB_02042	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HEOCKMHB_02043	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HEOCKMHB_02044	1.44e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_02045	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HEOCKMHB_02046	1.75e-269	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEOCKMHB_02047	6.92e-165	yebC	-	-	M	-	-	-	Membrane
HEOCKMHB_02049	1.08e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HEOCKMHB_02050	1.88e-39	yebG	-	-	S	-	-	-	NETI protein
HEOCKMHB_02051	1.87e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEOCKMHB_02052	1.15e-280	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEOCKMHB_02053	4.29e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEOCKMHB_02054	3.8e-163	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HEOCKMHB_02055	2.57e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOCKMHB_02056	4.32e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOCKMHB_02057	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEOCKMHB_02058	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEOCKMHB_02059	2.08e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HEOCKMHB_02060	1.16e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEOCKMHB_02061	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HEOCKMHB_02062	2.12e-293	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HEOCKMHB_02063	4.48e-81	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HEOCKMHB_02064	3.96e-173	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HEOCKMHB_02065	2.05e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HEOCKMHB_02066	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HEOCKMHB_02067	2.74e-243	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HEOCKMHB_02068	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02069	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HEOCKMHB_02070	5.04e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEOCKMHB_02071	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HEOCKMHB_02072	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEOCKMHB_02073	1.59e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HEOCKMHB_02074	6.11e-231	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HEOCKMHB_02075	7.98e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEOCKMHB_02076	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOCKMHB_02077	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEOCKMHB_02078	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEOCKMHB_02079	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEOCKMHB_02080	1.01e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02081	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEOCKMHB_02082	8.56e-217	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEOCKMHB_02083	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEOCKMHB_02084	0.0	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HEOCKMHB_02085	2.88e-204	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEOCKMHB_02086	3.92e-175	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HEOCKMHB_02087	5.92e-51	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEOCKMHB_02088	2.35e-73	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEOCKMHB_02089	2.48e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEOCKMHB_02090	1.69e-257	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HEOCKMHB_02091	6.14e-152	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	Belongs to the WXG100 family
HEOCKMHB_02092	1.27e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HEOCKMHB_02094	2.48e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HEOCKMHB_02095	1.32e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HEOCKMHB_02096	1.34e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HEOCKMHB_02097	4.26e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HEOCKMHB_02098	1.38e-114	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEOCKMHB_02100	1.26e-147	yetF	-	-	S	-	-	-	membrane
HEOCKMHB_02101	3.06e-70	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HEOCKMHB_02102	2.87e-82	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_02103	2.4e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEOCKMHB_02104	7.84e-29	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HEOCKMHB_02105	2.59e-73	-	-	-	H	-	-	-	riboflavin kinase activity
HEOCKMHB_02106	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEOCKMHB_02107	3.05e-110	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_02108	3.35e-246	yetM	-	-	CH	-	-	-	FAD binding domain
HEOCKMHB_02109	2.78e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HEOCKMHB_02110	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEOCKMHB_02112	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEOCKMHB_02113	1.4e-186	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HEOCKMHB_02114	5.59e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HEOCKMHB_02115	7.97e-222	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEOCKMHB_02116	7.97e-273	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HEOCKMHB_02117	5.43e-227	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEOCKMHB_02118	7.91e-271	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_02119	2.1e-306	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HEOCKMHB_02120	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOCKMHB_02121	3.69e-165	yfmS	-	-	NT	-	-	-	chemotaxis protein
HEOCKMHB_02122	1.93e-211	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEOCKMHB_02123	4.84e-256	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOCKMHB_02124	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOCKMHB_02125	8.36e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HEOCKMHB_02126	3.06e-249	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HEOCKMHB_02127	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEOCKMHB_02128	4.02e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HEOCKMHB_02129	3.25e-64	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HEOCKMHB_02130	1.41e-99	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HEOCKMHB_02131	9.03e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HEOCKMHB_02132	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HEOCKMHB_02133	5.26e-298	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEOCKMHB_02134	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEOCKMHB_02138	2.81e-67	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
HEOCKMHB_02139	2.85e-92	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
HEOCKMHB_02140	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HEOCKMHB_02141	4.78e-191	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEOCKMHB_02142	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HEOCKMHB_02143	5.54e-104	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HEOCKMHB_02144	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEOCKMHB_02145	4.96e-148	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEOCKMHB_02146	1.36e-217	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HEOCKMHB_02147	4.33e-282	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEOCKMHB_02148	5.2e-113	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEOCKMHB_02149	7.02e-269	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEOCKMHB_02150	4.43e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HEOCKMHB_02151	7.68e-150	yflK	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02152	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HEOCKMHB_02153	5.69e-26	yflI	-	-	-	-	-	-	-
HEOCKMHB_02154	1.38e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEOCKMHB_02155	1.05e-174	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEOCKMHB_02156	9.77e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEOCKMHB_02157	8.21e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HEOCKMHB_02158	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEOCKMHB_02159	3.87e-80	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HEOCKMHB_02160	2.68e-100	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEOCKMHB_02161	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEOCKMHB_02162	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEOCKMHB_02163	1.51e-43	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02164	3.65e-240	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02165	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEOCKMHB_02166	2.03e-162	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HEOCKMHB_02167	1.34e-154	frp	-	-	C	-	-	-	nitroreductase
HEOCKMHB_02168	1.06e-160	yibF	-	-	S	-	-	-	YibE/F-like protein
HEOCKMHB_02169	5.49e-235	yibE	-	-	S	-	-	-	YibE/F-like protein
HEOCKMHB_02170	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HEOCKMHB_02171	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HEOCKMHB_02172	2.99e-228	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEOCKMHB_02173	1.61e-205	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEOCKMHB_02174	5.75e-165	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEOCKMHB_02175	1.23e-245	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_02176	7.02e-40	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HEOCKMHB_02177	1.38e-102	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEOCKMHB_02178	2.71e-63	yfkI	-	-	S	-	-	-	gas vesicle protein
HEOCKMHB_02179	8.85e-182	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HEOCKMHB_02180	1.55e-273	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_02181	3.14e-234	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HEOCKMHB_02182	4.99e-180	yfkD	-	-	S	-	-	-	YfkD-like protein
HEOCKMHB_02183	5.34e-182	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HEOCKMHB_02184	9.38e-279	yfkA	-	-	S	-	-	-	YfkB-like domain
HEOCKMHB_02185	7.99e-37	yfjT	-	-	-	-	-	-	-
HEOCKMHB_02186	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HEOCKMHB_02187	7.52e-57	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEOCKMHB_02188	3.36e-87	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEOCKMHB_02190	5.27e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HEOCKMHB_02191	5.07e-201	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEOCKMHB_02192	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEOCKMHB_02193	3.05e-93	-	-	-	O	ko:K20486	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000,ko01002	Subtilase family
HEOCKMHB_02194	5.62e-307	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEOCKMHB_02195	0.0	-	-	-	KLT	-	-	-	Protein kinase domain
HEOCKMHB_02203	1.83e-60	-	-	-	S	-	-	-	YfzA-like protein
HEOCKMHB_02204	7.85e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEOCKMHB_02205	2.86e-102	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEOCKMHB_02206	2.95e-239	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEOCKMHB_02207	4.01e-237	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEOCKMHB_02208	7.82e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEOCKMHB_02209	3.32e-302	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEOCKMHB_02210	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HEOCKMHB_02211	3.29e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HEOCKMHB_02212	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEOCKMHB_02213	3.67e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HEOCKMHB_02214	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02215	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HEOCKMHB_02216	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEOCKMHB_02217	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEOCKMHB_02218	7.86e-82	yfiD3	-	-	S	-	-	-	DoxX
HEOCKMHB_02219	5.91e-199	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HEOCKMHB_02220	2.12e-99	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEOCKMHB_02221	1.49e-89	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEOCKMHB_02222	1e-119	padR	-	-	K	-	-	-	transcriptional
HEOCKMHB_02223	1.83e-128	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEOCKMHB_02224	2.39e-223	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEOCKMHB_02225	1.37e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEOCKMHB_02226	2.04e-122	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HEOCKMHB_02227	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HEOCKMHB_02228	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
HEOCKMHB_02229	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEOCKMHB_02230	1.27e-193	yfhB	-	-	S	-	-	-	PhzF family
HEOCKMHB_02231	3.09e-133	yfhC	-	-	C	-	-	-	nitroreductase
HEOCKMHB_02232	6.01e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
HEOCKMHB_02234	3.2e-210	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HEOCKMHB_02235	1.95e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HEOCKMHB_02236	3.93e-61	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HEOCKMHB_02237	6.7e-231	yfhI	-	-	EGP	-	-	-	-transporter
HEOCKMHB_02239	6.34e-201	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HEOCKMHB_02240	1.49e-58	yfhJ	-	-	S	-	-	-	WVELL protein
HEOCKMHB_02241	2.3e-112	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HEOCKMHB_02242	3.3e-10	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HEOCKMHB_02243	1.29e-23	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HEOCKMHB_02244	8.86e-119	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HEOCKMHB_02245	1.29e-234	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOCKMHB_02246	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HEOCKMHB_02247	4.29e-229	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HEOCKMHB_02248	8.93e-173	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEOCKMHB_02249	3.01e-56	-	-	-	E	-	-	-	Zn peptidase
HEOCKMHB_02250	7.33e-43	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_02251	3.24e-24	-	-	-	-	-	-	-	-
HEOCKMHB_02252	3.79e-39	-	-	-	-	-	-	-	-
HEOCKMHB_02255	1.37e-89	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HEOCKMHB_02258	8.43e-111	-	-	-	L	-	-	-	DnaD domain protein
HEOCKMHB_02259	1.06e-19	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
HEOCKMHB_02260	1.22e-210	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
HEOCKMHB_02261	1.36e-33	-	-	-	-	-	-	-	-
HEOCKMHB_02266	7.95e-37	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEOCKMHB_02267	9.73e-103	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEOCKMHB_02268	9.43e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HEOCKMHB_02269	1.87e-26	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HEOCKMHB_02273	1.72e-42	-	-	-	V	-	-	-	HNH nucleases
HEOCKMHB_02274	2.92e-61	-	-	-	L	-	-	-	Phage terminase, small subunit
HEOCKMHB_02275	0.0	-	-	-	S	-	-	-	Terminase
HEOCKMHB_02276	2.18e-86	-	-	-	S	-	-	-	Phage portal protein
HEOCKMHB_02277	1.1e-87	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEOCKMHB_02278	3.41e-145	-	-	-	S	-	-	-	Phage capsid family
HEOCKMHB_02285	1.04e-65	-	-	-	S	-	-	-	Phage-related minor tail protein
HEOCKMHB_02286	3.35e-59	-	-	-	S	-	-	-	Phage tail protein
HEOCKMHB_02287	2.45e-26	-	-	-	S	-	-	-	Prophage endopeptidase tail
HEOCKMHB_02289	2.7e-128	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEOCKMHB_02290	3.24e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEOCKMHB_02293	4.67e-29	bhlA	-	-	S	-	-	-	BhlA holin family
HEOCKMHB_02294	1.99e-33	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEOCKMHB_02295	5.67e-84	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_02298	3.07e-90	-	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEOCKMHB_02299	8.53e-13	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEOCKMHB_02300	3.84e-258	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HEOCKMHB_02301	1.47e-49	yfhS	-	-	-	-	-	-	-
HEOCKMHB_02302	1.73e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_02303	9.58e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HEOCKMHB_02304	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HEOCKMHB_02305	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HEOCKMHB_02306	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HEOCKMHB_02307	1.76e-237	ygaE	-	-	S	-	-	-	Membrane
HEOCKMHB_02308	1.27e-309	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEOCKMHB_02309	7.73e-109	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HEOCKMHB_02310	6.8e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HEOCKMHB_02311	1.1e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
HEOCKMHB_02312	2.08e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HEOCKMHB_02313	5.15e-124	yvbI	-	-	M	-	-	-	Membrane
HEOCKMHB_02314	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HEOCKMHB_02315	5.07e-103	yvbK	-	-	K	-	-	-	acetyltransferase
HEOCKMHB_02316	4.16e-260	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEOCKMHB_02317	1.87e-219	-	-	-	-	-	-	-	-
HEOCKMHB_02318	3.54e-159	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEOCKMHB_02319	1.13e-182	-	-	-	C	-	-	-	WbqC-like protein family
HEOCKMHB_02320	2.49e-179	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HEOCKMHB_02321	6.62e-279	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEOCKMHB_02322	6.48e-215	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HEOCKMHB_02323	2.68e-275	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEOCKMHB_02324	9.36e-317	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOCKMHB_02325	2.83e-286	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HEOCKMHB_02326	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEOCKMHB_02327	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HEOCKMHB_02328	1.49e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEOCKMHB_02329	1.55e-274	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HEOCKMHB_02330	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEOCKMHB_02331	1.91e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEOCKMHB_02333	4.6e-272	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEOCKMHB_02334	1.76e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HEOCKMHB_02335	1.78e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_02336	3.86e-18	yvbU	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02337	2.18e-124	yvbU	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02338	5.35e-196	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HEOCKMHB_02339	6.69e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_02341	2.88e-190	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HEOCKMHB_02342	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEOCKMHB_02343	3.08e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HEOCKMHB_02344	3.12e-167	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEOCKMHB_02345	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEOCKMHB_02346	1.69e-170	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEOCKMHB_02347	2.07e-264	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOCKMHB_02348	1.16e-151	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HEOCKMHB_02349	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEOCKMHB_02350	1.33e-292	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEOCKMHB_02351	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HEOCKMHB_02352	1.45e-179	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HEOCKMHB_02353	1.53e-27	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HEOCKMHB_02354	2.79e-275	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HEOCKMHB_02355	1.28e-70	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEOCKMHB_02356	2.7e-131	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEOCKMHB_02357	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_02358	1.99e-238	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOCKMHB_02359	6.55e-251	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HEOCKMHB_02360	6.01e-245	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEOCKMHB_02361	6.38e-258	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HEOCKMHB_02362	1.95e-253	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEOCKMHB_02363	3.44e-200	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEOCKMHB_02364	3.48e-268	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HEOCKMHB_02365	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEOCKMHB_02366	4.44e-151	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEOCKMHB_02367	4.37e-151	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEOCKMHB_02368	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HEOCKMHB_02369	8.66e-312	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HEOCKMHB_02371	8.3e-111	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HEOCKMHB_02372	4.2e-164	-	-	-	CH	-	-	-	FAD binding domain
HEOCKMHB_02373	2.74e-98	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEOCKMHB_02374	5.22e-137	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HEOCKMHB_02375	3.65e-108	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOCKMHB_02376	7.09e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HEOCKMHB_02377	1.25e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HEOCKMHB_02378	3.4e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEOCKMHB_02379	1.63e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEOCKMHB_02380	6.57e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEOCKMHB_02381	0.0	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HEOCKMHB_02382	3.08e-44	-	-	-	-	-	-	-	-
HEOCKMHB_02384	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEOCKMHB_02385	5.05e-279	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HEOCKMHB_02386	2.68e-226	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEOCKMHB_02387	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEOCKMHB_02388	1.4e-202	yraN	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02389	3.16e-258	yraM	-	-	S	-	-	-	PrpF protein
HEOCKMHB_02390	6.64e-313	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HEOCKMHB_02391	1.06e-110	-	-	-	-	-	-	-	-
HEOCKMHB_02392	2.87e-132	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HEOCKMHB_02393	5.98e-66	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HEOCKMHB_02394	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEOCKMHB_02395	1.42e-133	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEOCKMHB_02396	7.72e-229	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEOCKMHB_02397	4.11e-100	-	-	-	M	-	-	-	Ribonuclease
HEOCKMHB_02398	5.8e-167	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HEOCKMHB_02399	6.52e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HEOCKMHB_02400	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HEOCKMHB_02401	3.01e-224	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEOCKMHB_02402	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HEOCKMHB_02403	7.32e-113	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEOCKMHB_02404	6.06e-224	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEOCKMHB_02405	7.8e-192	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HEOCKMHB_02406	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEOCKMHB_02407	1.01e-231	sasA	-	-	T	-	-	-	Histidine kinase
HEOCKMHB_02408	1.49e-153	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_02409	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEOCKMHB_02410	8.74e-139	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HEOCKMHB_02411	4.63e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEOCKMHB_02412	6.02e-163	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEOCKMHB_02413	1.75e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEOCKMHB_02414	6.49e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HEOCKMHB_02415	4.77e-279	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEOCKMHB_02416	1.45e-145	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEOCKMHB_02417	8.64e-258	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEOCKMHB_02418	3.83e-173	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HEOCKMHB_02419	1.2e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEOCKMHB_02420	3.18e-155	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEOCKMHB_02421	5.06e-193	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEOCKMHB_02422	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEOCKMHB_02423	2.47e-272	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEOCKMHB_02424	1.44e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEOCKMHB_02425	2.9e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HEOCKMHB_02426	6.76e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEOCKMHB_02427	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HEOCKMHB_02428	1.09e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HEOCKMHB_02429	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HEOCKMHB_02430	4.14e-214	yvlB	-	-	S	-	-	-	Putative adhesin
HEOCKMHB_02431	1.79e-61	yvlA	-	-	-	-	-	-	-
HEOCKMHB_02432	1.29e-40	yvkN	-	-	-	-	-	-	-
HEOCKMHB_02433	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEOCKMHB_02434	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEOCKMHB_02435	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02436	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HEOCKMHB_02437	1.12e-119	yvkB	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02438	3.49e-290	yvkA	-	-	P	-	-	-	-transporter
HEOCKMHB_02441	1.39e-278	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOCKMHB_02442	5.83e-72	swrA	-	-	S	-	-	-	Swarming motility protein
HEOCKMHB_02443	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEOCKMHB_02444	1.35e-271	ywoF	-	-	P	-	-	-	Right handed beta helix region
HEOCKMHB_02445	1.48e-196	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEOCKMHB_02446	3.53e-158	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HEOCKMHB_02447	1.47e-58	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEOCKMHB_02448	5.39e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_02449	1.08e-222	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEOCKMHB_02450	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEOCKMHB_02451	4.25e-130	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEOCKMHB_02452	1.92e-89	-	-	-	-	-	-	-	-
HEOCKMHB_02453	1.57e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HEOCKMHB_02454	2.18e-83	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HEOCKMHB_02455	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEOCKMHB_02456	9.98e-154	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEOCKMHB_02457	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEOCKMHB_02458	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEOCKMHB_02459	1.27e-104	yviE	-	-	-	-	-	-	-
HEOCKMHB_02460	1.63e-206	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HEOCKMHB_02461	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HEOCKMHB_02462	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
HEOCKMHB_02463	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HEOCKMHB_02464	6.15e-95	yvyF	-	-	S	-	-	-	flagellar protein
HEOCKMHB_02465	4.91e-79	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HEOCKMHB_02466	2.93e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HEOCKMHB_02467	5.41e-316	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEOCKMHB_02468	3.16e-197	degV	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02469	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOCKMHB_02470	2.31e-245	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEOCKMHB_02471	1.1e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HEOCKMHB_02472	9.24e-234	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02473	8.94e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEOCKMHB_02474	4.55e-285	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HEOCKMHB_02475	2.22e-182	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEOCKMHB_02476	8.08e-138	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HEOCKMHB_02477	8.4e-317	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HEOCKMHB_02478	5.86e-310	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOCKMHB_02479	2.76e-270	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HEOCKMHB_02480	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_02481	8.51e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEOCKMHB_02482	4.43e-268	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_02483	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HEOCKMHB_02484	1.99e-39	-	-	-	-	-	-	-	-
HEOCKMHB_02485	1.15e-179	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEOCKMHB_02486	8.48e-235	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEOCKMHB_02487	2.14e-200	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEOCKMHB_02488	1.55e-241	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEOCKMHB_02489	7.77e-174	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HEOCKMHB_02490	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOCKMHB_02491	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferase 1 domain A
HEOCKMHB_02492	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HEOCKMHB_02493	6.85e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEOCKMHB_02494	5.65e-258	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEOCKMHB_02495	2.3e-290	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEOCKMHB_02496	9.82e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEOCKMHB_02497	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEOCKMHB_02498	2.94e-243	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEOCKMHB_02499	3.1e-218	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HEOCKMHB_02500	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HEOCKMHB_02501	9.98e-304	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEOCKMHB_02502	2.02e-223	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02503	1.33e-195	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEOCKMHB_02504	1.4e-60	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HEOCKMHB_02505	1.37e-288	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEOCKMHB_02506	1.16e-28	ywtC	-	-	-	-	-	-	-
HEOCKMHB_02507	7.41e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEOCKMHB_02508	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HEOCKMHB_02509	8.45e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEOCKMHB_02510	1.63e-244	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEOCKMHB_02511	6.95e-228	-	-	-	E	-	-	-	Spore germination protein
HEOCKMHB_02512	3.22e-63	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HEOCKMHB_02513	4.74e-144	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HEOCKMHB_02514	1.08e-221	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEOCKMHB_02515	2.47e-195	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEOCKMHB_02516	3.79e-83	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEOCKMHB_02517	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEOCKMHB_02518	7.29e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEOCKMHB_02519	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HEOCKMHB_02520	6.3e-111	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HEOCKMHB_02521	2.39e-115	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HEOCKMHB_02522	3.56e-185	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HEOCKMHB_02523	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEOCKMHB_02524	5.73e-210	alsR	-	-	K	-	-	-	LysR substrate binding domain
HEOCKMHB_02525	5.9e-297	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEOCKMHB_02526	8.96e-150	ywrJ	-	-	-	-	-	-	-
HEOCKMHB_02527	4.38e-157	cotB	-	-	-	ko:K06325	-	ko00000	-
HEOCKMHB_02528	9.11e-261	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HEOCKMHB_02529	4.7e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEOCKMHB_02531	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEOCKMHB_02532	3.97e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEOCKMHB_02533	7.48e-126	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HEOCKMHB_02534	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HEOCKMHB_02535	1.29e-130	-	-	-	-	-	-	-	-
HEOCKMHB_02536	7.15e-83	-	-	-	-	-	-	-	-
HEOCKMHB_02537	3.77e-97	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
HEOCKMHB_02538	1.92e-25	-	-	-	-	-	-	-	-
HEOCKMHB_02539	2.19e-75	-	-	-	S	-	-	-	SUKH-4 immunity protein
HEOCKMHB_02540	2.69e-288	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HEOCKMHB_02541	1.36e-48	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HEOCKMHB_02543	3.03e-183	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HEOCKMHB_02544	2.45e-304	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEOCKMHB_02545	4.63e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HEOCKMHB_02546	3.37e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEOCKMHB_02547	8.45e-144	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEOCKMHB_02548	3e-22	-	-	-	-	-	-	-	-
HEOCKMHB_02549	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HEOCKMHB_02550	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEOCKMHB_02551	1.28e-193	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEOCKMHB_02552	5.39e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HEOCKMHB_02553	4.94e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HEOCKMHB_02554	1.83e-74	ywpG	-	-	-	-	-	-	-
HEOCKMHB_02555	1.79e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
HEOCKMHB_02556	2.54e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEOCKMHB_02557	3.15e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEOCKMHB_02558	4.41e-247	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HEOCKMHB_02559	5.1e-176	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEOCKMHB_02560	1.16e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEOCKMHB_02561	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HEOCKMHB_02562	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HEOCKMHB_02563	5.3e-93	ywoH	-	-	K	-	-	-	transcriptional
HEOCKMHB_02564	3.92e-270	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_02565	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HEOCKMHB_02566	1.81e-308	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HEOCKMHB_02567	2.1e-128	yjgF	-	-	Q	-	-	-	Isochorismatase family
HEOCKMHB_02568	3.63e-289	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HEOCKMHB_02569	1.51e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HEOCKMHB_02570	1.11e-262	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEOCKMHB_02571	5.56e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HEOCKMHB_02572	3.41e-88	ywnJ	-	-	S	-	-	-	VanZ like family
HEOCKMHB_02573	1.67e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEOCKMHB_02574	7.6e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HEOCKMHB_02576	2.45e-88	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HEOCKMHB_02577	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOCKMHB_02578	1.12e-21	yqgA	-	-	-	-	-	-	-
HEOCKMHB_02579	1.33e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HEOCKMHB_02580	3.75e-116	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HEOCKMHB_02581	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02582	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEOCKMHB_02583	4.37e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HEOCKMHB_02584	1.94e-66	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HEOCKMHB_02585	2.41e-16	csbD	-	-	K	-	-	-	CsbD-like
HEOCKMHB_02586	1.01e-105	ywmF	-	-	S	-	-	-	Peptidase M50
HEOCKMHB_02587	2.9e-90	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEOCKMHB_02588	2.09e-243	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEOCKMHB_02589	2.91e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEOCKMHB_02591	2.79e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEOCKMHB_02592	4.74e-145	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEOCKMHB_02593	6.86e-232	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HEOCKMHB_02594	1.85e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEOCKMHB_02595	1.27e-169	ywmB	-	-	S	-	-	-	TATA-box binding
HEOCKMHB_02596	1.85e-44	ywzB	-	-	S	-	-	-	membrane
HEOCKMHB_02597	1.98e-115	ywmA	-	-	-	-	-	-	-
HEOCKMHB_02598	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HEOCKMHB_02599	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEOCKMHB_02600	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEOCKMHB_02601	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEOCKMHB_02602	1.95e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEOCKMHB_02603	3.35e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEOCKMHB_02604	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEOCKMHB_02605	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HEOCKMHB_02606	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HEOCKMHB_02607	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEOCKMHB_02608	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEOCKMHB_02609	3.53e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HEOCKMHB_02610	9.2e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HEOCKMHB_02611	1.84e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEOCKMHB_02612	1.86e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEOCKMHB_02613	1.34e-237	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEOCKMHB_02614	6.75e-96	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HEOCKMHB_02615	7.05e-148	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HEOCKMHB_02616	4.04e-77	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEOCKMHB_02618	1.18e-194	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEOCKMHB_02619	8.38e-240	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEOCKMHB_02620	6.91e-84	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_02621	2.52e-115	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEOCKMHB_02622	6.87e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEOCKMHB_02623	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEOCKMHB_02624	3.09e-129	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HEOCKMHB_02625	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HEOCKMHB_02626	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEOCKMHB_02627	6.51e-221	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HEOCKMHB_02628	1.59e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEOCKMHB_02629	3.69e-143	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEOCKMHB_02630	4.53e-203	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HEOCKMHB_02631	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HEOCKMHB_02632	1.84e-117	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HEOCKMHB_02633	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEOCKMHB_02634	1.53e-71	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEOCKMHB_02635	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HEOCKMHB_02636	1.51e-263	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEOCKMHB_02637	5.39e-224	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEOCKMHB_02638	3.23e-58	ywjC	-	-	-	-	-	-	-
HEOCKMHB_02639	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEOCKMHB_02640	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEOCKMHB_02641	1.61e-149	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HEOCKMHB_02642	1.07e-110	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HEOCKMHB_02643	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HEOCKMHB_02644	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOCKMHB_02645	8.63e-102	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HEOCKMHB_02646	8.59e-162	ywiC	-	-	S	-	-	-	YwiC-like protein
HEOCKMHB_02647	1.67e-161	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HEOCKMHB_02648	7.56e-267	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEOCKMHB_02649	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HEOCKMHB_02650	4.46e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02652	8.63e-110	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HEOCKMHB_02653	2.22e-123	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HEOCKMHB_02654	3.16e-102	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEOCKMHB_02656	2.87e-213	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEOCKMHB_02657	6.45e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEOCKMHB_02658	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEOCKMHB_02659	1.96e-93	-	-	-	-	-	-	-	-
HEOCKMHB_02660	2.07e-116	ywhD	-	-	S	-	-	-	YwhD family
HEOCKMHB_02661	1.29e-151	ywhC	-	-	S	-	-	-	Peptidase family M50
HEOCKMHB_02662	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HEOCKMHB_02663	3.29e-90	ywhA	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02664	4.79e-307	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HEOCKMHB_02665	1.37e-113	ywgA	-	-	-	ko:K09388	-	ko00000	-
HEOCKMHB_02666	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HEOCKMHB_02667	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HEOCKMHB_02668	3.27e-136	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HEOCKMHB_02669	4.41e-67	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HEOCKMHB_02670	2.51e-109	-	-	-	S	-	-	-	membrane
HEOCKMHB_02671	1.93e-194	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_02672	2.13e-208	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEOCKMHB_02675	4.4e-208	-	-	-	-	-	-	-	-
HEOCKMHB_02677	8.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEOCKMHB_02678	1.33e-199	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_02679	9.29e-207	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HEOCKMHB_02680	2.27e-222	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HEOCKMHB_02681	6.64e-185	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HEOCKMHB_02682	2.37e-20	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HEOCKMHB_02684	6.08e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HEOCKMHB_02685	5.35e-289	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HEOCKMHB_02686	2.33e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HEOCKMHB_02687	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEOCKMHB_02688	2.21e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_02689	1.63e-174	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEOCKMHB_02690	1.16e-107	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEOCKMHB_02691	8.02e-277	ywfA	-	-	EGP	-	-	-	-transporter
HEOCKMHB_02692	4.86e-249	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEOCKMHB_02693	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEOCKMHB_02694	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HEOCKMHB_02695	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEOCKMHB_02696	8.64e-312	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEOCKMHB_02697	4.02e-80	-	-	-	-	-	-	-	-
HEOCKMHB_02698	2.6e-109	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HEOCKMHB_02699	3.3e-199	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEOCKMHB_02700	5.41e-226	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEOCKMHB_02701	2.9e-170	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEOCKMHB_02702	3.01e-212	spsG	-	-	M	-	-	-	Spore Coat
HEOCKMHB_02703	5.52e-160	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HEOCKMHB_02704	2.97e-266	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HEOCKMHB_02705	6.34e-195	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HEOCKMHB_02706	2.58e-275	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEOCKMHB_02707	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HEOCKMHB_02708	4.13e-180	spsA	-	-	M	-	-	-	Spore Coat
HEOCKMHB_02709	1.29e-83	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEOCKMHB_02710	4.39e-76	ywdK	-	-	S	-	-	-	small membrane protein
HEOCKMHB_02711	3.47e-287	ywdJ	-	-	F	-	-	-	Xanthine uracil
HEOCKMHB_02712	2.73e-56	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HEOCKMHB_02713	2.42e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEOCKMHB_02714	1.44e-186	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HEOCKMHB_02716	2.79e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEOCKMHB_02717	6.09e-27	ywdA	-	-	-	-	-	-	-
HEOCKMHB_02718	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEOCKMHB_02719	9.04e-317	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02720	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEOCKMHB_02722	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEOCKMHB_02723	1.83e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_02724	1.26e-150	-	-	-	K	-	-	-	WYL domain
HEOCKMHB_02725	4.96e-161	ucpA	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_02726	4.61e-56	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
HEOCKMHB_02727	1.36e-39	-	-	-	S	-	-	-	PFAM Stress responsive alpha-beta barrel
HEOCKMHB_02728	1.1e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HEOCKMHB_02729	1.84e-262	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HEOCKMHB_02730	1.68e-87	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HEOCKMHB_02731	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HEOCKMHB_02732	1.08e-80	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEOCKMHB_02733	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEOCKMHB_02734	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEOCKMHB_02735	3.01e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEOCKMHB_02736	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HEOCKMHB_02737	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEOCKMHB_02738	1.52e-265	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEOCKMHB_02739	7.8e-78	gtcA	-	-	S	-	-	-	GtrA-like protein
HEOCKMHB_02740	1.72e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEOCKMHB_02742	6.64e-162	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HEOCKMHB_02743	4.83e-154	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HEOCKMHB_02744	5.52e-139	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEOCKMHB_02745	9.8e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HEOCKMHB_02746	5.83e-191	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HEOCKMHB_02747	2.41e-246	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HEOCKMHB_02748	2.72e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEOCKMHB_02749	9.98e-164	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEOCKMHB_02750	2.29e-200	ywbI	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02751	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEOCKMHB_02752	6.2e-142	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HEOCKMHB_02753	1.52e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HEOCKMHB_02754	2.16e-164	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HEOCKMHB_02755	1.97e-200	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HEOCKMHB_02756	4.69e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HEOCKMHB_02757	1.24e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HEOCKMHB_02758	8.3e-309	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOCKMHB_02759	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEOCKMHB_02760	2.87e-205	gspA	-	-	M	-	-	-	General stress
HEOCKMHB_02762	2.16e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HEOCKMHB_02763	7.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HEOCKMHB_02764	3.51e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HEOCKMHB_02765	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_02766	2.45e-289	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HEOCKMHB_02767	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_02768	3.02e-244	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEOCKMHB_02769	1.29e-259	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEOCKMHB_02770	2.82e-315	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEOCKMHB_02771	1.89e-64	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02772	4.85e-312	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOCKMHB_02773	3.67e-65	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HEOCKMHB_02774	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HEOCKMHB_02775	4.07e-139	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HEOCKMHB_02776	6.1e-216	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_02777	9.33e-229	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_02778	8.85e-212	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEOCKMHB_02779	1.06e-66	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HEOCKMHB_02780	1.16e-286	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEOCKMHB_02781	1.35e-58	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02782	1.26e-62	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02783	1.84e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEOCKMHB_02784	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEOCKMHB_02785	7.52e-206	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HEOCKMHB_02786	1.05e-227	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEOCKMHB_02787	3.3e-261	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HEOCKMHB_02788	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEOCKMHB_02789	1.26e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HEOCKMHB_02790	2.06e-313	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HEOCKMHB_02791	7.18e-140	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEOCKMHB_02792	6.72e-37	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEOCKMHB_02793	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HEOCKMHB_02794	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HEOCKMHB_02795	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HEOCKMHB_02796	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEOCKMHB_02797	1.02e-283	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HEOCKMHB_02798	2.39e-191	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HEOCKMHB_02799	3.56e-259	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_02800	1.49e-198	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HEOCKMHB_02801	4.82e-190	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEOCKMHB_02803	5.75e-115	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HEOCKMHB_02804	7.02e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEOCKMHB_02805	5.24e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HEOCKMHB_02808	3.81e-105	yxjI	-	-	S	-	-	-	LURP-one-related
HEOCKMHB_02809	8.25e-271	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HEOCKMHB_02810	2.83e-185	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HEOCKMHB_02811	2.49e-262	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOCKMHB_02812	1.64e-113	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HEOCKMHB_02813	3.23e-60	yxiS	-	-	-	-	-	-	-
HEOCKMHB_02814	3.04e-221	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HEOCKMHB_02815	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEOCKMHB_02816	2.74e-227	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEOCKMHB_02817	9.73e-176	bglS	-	-	M	-	-	-	licheninase activity
HEOCKMHB_02818	2.11e-183	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEOCKMHB_02819	7.88e-277	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HEOCKMHB_02820	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEOCKMHB_02822	9.75e-27	-	-	-	-	-	-	-	-
HEOCKMHB_02824	2.79e-140	-	-	-	-	-	-	-	-
HEOCKMHB_02825	4.23e-103	-	-	-	-	-	-	-	-
HEOCKMHB_02826	2.91e-85	yxiG	-	-	-	-	-	-	-
HEOCKMHB_02827	9.79e-75	yxxG	-	-	-	-	-	-	-
HEOCKMHB_02829	4.8e-251	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEOCKMHB_02830	7.42e-202	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HEOCKMHB_02831	2.44e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEOCKMHB_02832	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEOCKMHB_02833	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_02834	1.51e-61	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HEOCKMHB_02835	8.04e-176	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HEOCKMHB_02836	3.55e-204	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HEOCKMHB_02837	0.0	-	-	-	L	-	-	-	Z1 domain
HEOCKMHB_02838	1.12e-99	-	-	-	S	-	-	-	Putative PD-(D/E)XK family member, (DUF4420)
HEOCKMHB_02839	2.49e-244	-	-	-	S	-	-	-	AIPR protein
HEOCKMHB_02840	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEOCKMHB_02841	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEOCKMHB_02842	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HEOCKMHB_02843	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEOCKMHB_02844	7.66e-291	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HEOCKMHB_02845	6.73e-216	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEOCKMHB_02846	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEOCKMHB_02847	7.43e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HEOCKMHB_02848	2.33e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOCKMHB_02849	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEOCKMHB_02850	1.55e-94	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEOCKMHB_02851	1.13e-103	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEOCKMHB_02852	1.75e-188	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEOCKMHB_02855	9.45e-26	yxeE	-	-	-	-	-	-	-
HEOCKMHB_02857	9.67e-33	yxeD	-	-	-	-	-	-	-
HEOCKMHB_02858	4.86e-47	-	-	-	-	-	-	-	-
HEOCKMHB_02859	6.74e-218	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEOCKMHB_02860	2.25e-72	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HEOCKMHB_02861	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEOCKMHB_02862	7.1e-177	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_02863	9.27e-223	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_02864	6.33e-157	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_02865	1.61e-194	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEOCKMHB_02866	6.65e-198	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEOCKMHB_02867	4.92e-209	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HEOCKMHB_02868	2.36e-246	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEOCKMHB_02869	6.5e-288	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HEOCKMHB_02870	1.73e-218	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEOCKMHB_02871	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEOCKMHB_02872	1e-224	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEOCKMHB_02873	1.11e-196	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEOCKMHB_02874	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOCKMHB_02875	1.75e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEOCKMHB_02876	1.72e-215	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HEOCKMHB_02877	2.13e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEOCKMHB_02878	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HEOCKMHB_02879	1.56e-188	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEOCKMHB_02880	2.06e-129	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOCKMHB_02881	3.16e-243	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_02882	1.04e-247	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HEOCKMHB_02883	1.53e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEOCKMHB_02884	2.4e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEOCKMHB_02885	2.12e-185	yxaL	-	-	S	-	-	-	PQQ-like domain
HEOCKMHB_02886	5.81e-75	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HEOCKMHB_02887	3.34e-65	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEOCKMHB_02888	1.16e-250	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEOCKMHB_02889	1.49e-85	yxaI	-	-	S	-	-	-	membrane protein domain
HEOCKMHB_02890	3.07e-120	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HEOCKMHB_02891	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HEOCKMHB_02892	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HEOCKMHB_02893	9.59e-234	mrjp	-	-	G	-	-	-	Major royal jelly protein
HEOCKMHB_02894	1.26e-301	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_02895	9.17e-200	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HEOCKMHB_02896	2.97e-95	-	-	-	K	-	-	-	Integron-associated effector binding protein
HEOCKMHB_02897	6.31e-98	yjhE	-	-	S	-	-	-	Phage tail protein
HEOCKMHB_02898	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEOCKMHB_02899	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEOCKMHB_02900	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HEOCKMHB_02901	1.25e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEOCKMHB_02902	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HEOCKMHB_02903	2.83e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEOCKMHB_02904	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEOCKMHB_02905	1.84e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEOCKMHB_02906	6.08e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEOCKMHB_02907	7.08e-137	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HEOCKMHB_02908	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEOCKMHB_02909	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEOCKMHB_02910	2.56e-161	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEOCKMHB_02911	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEOCKMHB_02912	2.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HEOCKMHB_02913	2.76e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEOCKMHB_02914	1.3e-139	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HEOCKMHB_02915	2.63e-74	yhhY	-	-	K	-	-	-	FR47-like protein
HEOCKMHB_02916	3.84e-215	yyaD	-	-	S	-	-	-	Membrane
HEOCKMHB_02917	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02918	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEOCKMHB_02919	6.32e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEOCKMHB_02920	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HEOCKMHB_02921	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEOCKMHB_02922	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEOCKMHB_02923	3.59e-123	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HEOCKMHB_02924	6.58e-112	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEOCKMHB_02925	2.49e-179	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEOCKMHB_02926	6.26e-78	ccpB	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02927	1.16e-117	ccpB	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02928	9.47e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_02929	2.8e-311	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HEOCKMHB_02930	4.75e-193	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEOCKMHB_02931	7.39e-264	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HEOCKMHB_02932	7.1e-207	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HEOCKMHB_02933	1.25e-88	ynaF	-	-	-	-	-	-	-
HEOCKMHB_02934	8.63e-130	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HEOCKMHB_02935	5e-27	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEOCKMHB_02936	2.85e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_02937	7.24e-97	yybA	-	-	K	-	-	-	transcriptional
HEOCKMHB_02938	7.02e-190	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_02939	2.55e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEOCKMHB_02940	1.56e-144	ydgI	-	-	C	-	-	-	nitroreductase
HEOCKMHB_02941	3.76e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HEOCKMHB_02942	1.96e-184	-	-	-	G	-	-	-	Major Facilitator Superfamily
HEOCKMHB_02943	3.74e-115	-	-	-	S	-	-	-	PFAM DinB family protein
HEOCKMHB_02944	7.61e-142	-	-	-	K	-	-	-	FCD domain
HEOCKMHB_02945	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HEOCKMHB_02946	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HEOCKMHB_02947	4.42e-192	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOCKMHB_02948	4.01e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HEOCKMHB_02949	1.79e-84	yybR	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_02950	3.93e-104	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HEOCKMHB_02952	8.64e-189	yybS	-	-	S	-	-	-	membrane
HEOCKMHB_02953	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEOCKMHB_02954	2.25e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEOCKMHB_02955	4.29e-103	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HEOCKMHB_02956	1.44e-150	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEOCKMHB_02957	3.93e-279	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEOCKMHB_02958	2.87e-291	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HEOCKMHB_02959	4.55e-243	-	-	-	S	-	-	-	Ecdysteroid kinase
HEOCKMHB_02960	3.86e-271	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEOCKMHB_02961	1.21e-23	yycC	-	-	K	-	-	-	YycC-like protein
HEOCKMHB_02963	5.03e-35	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HEOCKMHB_02964	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HEOCKMHB_02965	1.06e-92	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_02966	4.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEOCKMHB_02971	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_02972	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_02973	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02974	6.34e-191	yycI	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_02975	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEOCKMHB_02976	1.37e-270	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOCKMHB_02977	6.88e-86	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HEOCKMHB_02978	3.35e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
HEOCKMHB_02979	4.44e-309	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEOCKMHB_02980	8.24e-255	-	-	-	S	-	-	-	Major Facilitator Superfamily
HEOCKMHB_02981	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEOCKMHB_02982	3.82e-57	sdpR	-	-	K	-	-	-	transcriptional
HEOCKMHB_02983	1.26e-85	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEOCKMHB_02984	1.75e-295	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEOCKMHB_02985	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEOCKMHB_02986	7.27e-210	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEOCKMHB_02987	2.05e-256	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HEOCKMHB_02989	2.13e-106	yycN	-	-	K	-	-	-	Acetyltransferase
HEOCKMHB_02990	3.13e-226	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEOCKMHB_02991	1.54e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEOCKMHB_02992	5.96e-264	yycP	-	-	-	-	-	-	-
HEOCKMHB_02996	1.01e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEOCKMHB_02997	0.0	-	-	-	L	-	-	-	AAA ATPase domain
HEOCKMHB_02998	1.63e-281	-	-	-	L	-	-	-	AAA domain
HEOCKMHB_02999	1.74e-53	-	-	-	L	-	-	-	AAA domain
HEOCKMHB_03000	6.58e-27	-	-	-	-	-	-	-	-
HEOCKMHB_03001	3.9e-208	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HEOCKMHB_03002	7.21e-200	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEOCKMHB_03003	8.88e-106	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HEOCKMHB_03004	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEOCKMHB_03005	1.16e-182	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEOCKMHB_03006	1.13e-101	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEOCKMHB_03007	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HEOCKMHB_03008	1.16e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEOCKMHB_03009	0.0	-	-	-	I	-	-	-	PLD-like domain
HEOCKMHB_03010	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEOCKMHB_03011	6.56e-192	-	-	-	S	-	-	-	membrane
HEOCKMHB_03012	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HEOCKMHB_03013	6.17e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEOCKMHB_03014	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HEOCKMHB_03015	4.11e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HEOCKMHB_03016	4.82e-103	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEOCKMHB_03017	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HEOCKMHB_03019	4.04e-103	-	-	-	-	-	-	-	-
HEOCKMHB_03020	2.84e-123	tnpR	-	-	L	-	-	-	resolvase
HEOCKMHB_03021	0.0	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HEOCKMHB_03022	1.55e-134	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HEOCKMHB_03023	2.67e-125	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEOCKMHB_03024	1.21e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEOCKMHB_03025	5.4e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOCKMHB_03026	2.99e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEOCKMHB_03027	2.95e-139	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOCKMHB_03028	3.5e-108	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEOCKMHB_03029	1.25e-262	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEOCKMHB_03030	7.36e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOCKMHB_03031	5.17e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEOCKMHB_03032	1.41e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEOCKMHB_03033	1.27e-160	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_03034	1.91e-154	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEOCKMHB_03035	4.95e-170	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEOCKMHB_03036	7.17e-154	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HEOCKMHB_03037	3.51e-308	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HEOCKMHB_03038	1.17e-67	yvaP	-	-	K	-	-	-	transcriptional
HEOCKMHB_03039	1.09e-90	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HEOCKMHB_03040	1.07e-89	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HEOCKMHB_03041	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HEOCKMHB_03042	9.24e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HEOCKMHB_03043	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HEOCKMHB_03044	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEOCKMHB_03045	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEOCKMHB_03047	9.41e-56	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEOCKMHB_03048	1.18e-179	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_03049	4.27e-201	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HEOCKMHB_03050	5.25e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEOCKMHB_03051	3.28e-167	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEOCKMHB_03052	1.8e-181	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEOCKMHB_03053	1.35e-152	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEOCKMHB_03054	5.33e-152	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEOCKMHB_03055	3.93e-175	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEOCKMHB_03056	1.43e-225	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_03057	1.97e-59	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HEOCKMHB_03058	0.0	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_03059	1.03e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOCKMHB_03060	4.69e-238	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEOCKMHB_03061	8.06e-64	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HEOCKMHB_03062	9.29e-40	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HEOCKMHB_03063	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEOCKMHB_03064	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEOCKMHB_03065	2.51e-135	bdbD	-	-	O	-	-	-	Thioredoxin
HEOCKMHB_03066	5.06e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HEOCKMHB_03067	5.24e-188	-	-	-	S	-	-	-	Metallo-peptidase family M12
HEOCKMHB_03068	6.1e-128	yvgT	-	-	S	-	-	-	membrane
HEOCKMHB_03070	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEOCKMHB_03071	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEOCKMHB_03072	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEOCKMHB_03073	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HEOCKMHB_03074	1.55e-110	yvgO	-	-	-	-	-	-	-
HEOCKMHB_03075	1.77e-200	yvgN	-	-	S	-	-	-	reductase
HEOCKMHB_03076	1.44e-229	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HEOCKMHB_03077	3.65e-235	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEOCKMHB_03078	1.12e-216	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HEOCKMHB_03079	3.01e-237	-	-	-	T	-	-	-	Histidine kinase
HEOCKMHB_03080	4.14e-146	yfiK	-	-	K	-	-	-	Regulator
HEOCKMHB_03081	4.14e-118	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HEOCKMHB_03082	4.92e-174	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HEOCKMHB_03083	8.02e-204	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HEOCKMHB_03084	2.24e-203	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HEOCKMHB_03085	3.8e-210	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HEOCKMHB_03086	2.04e-110	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HEOCKMHB_03087	4.34e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HEOCKMHB_03088	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEOCKMHB_03089	2.17e-153	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEOCKMHB_03090	2.12e-226	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEOCKMHB_03091	6.08e-234	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03092	9.44e-217	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03093	6.61e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEOCKMHB_03094	1.37e-78	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HEOCKMHB_03095	9.98e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEOCKMHB_03096	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
HEOCKMHB_03097	1.47e-130	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HEOCKMHB_03098	1.14e-48	-	-	-	-	-	-	-	-
HEOCKMHB_03099	4.48e-171	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_03100	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HEOCKMHB_03101	2.36e-213	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HEOCKMHB_03102	4.79e-178	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_03103	1.07e-211	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEOCKMHB_03104	5.73e-224	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03105	5.35e-257	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEOCKMHB_03106	3.89e-125	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HEOCKMHB_03107	9.45e-281	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_03108	7.39e-65	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HEOCKMHB_03109	6e-128	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEOCKMHB_03110	1.33e-165	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HEOCKMHB_03111	6.74e-159	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HEOCKMHB_03112	2.86e-246	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_03113	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOCKMHB_03114	9.22e-248	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HEOCKMHB_03115	3e-235	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEOCKMHB_03116	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEOCKMHB_03117	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HEOCKMHB_03118	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEOCKMHB_03119	6.7e-196	yuxN	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03120	2.68e-32	-	-	-	-	-	-	-	-
HEOCKMHB_03121	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_03122	2.06e-160	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_03123	8.65e-295	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEOCKMHB_03124	5.63e-101	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEOCKMHB_03125	1.77e-177	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_03126	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HEOCKMHB_03127	2.79e-62	-	-	-	S	-	-	-	YusW-like protein
HEOCKMHB_03128	1.06e-191	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEOCKMHB_03129	1.46e-50	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HEOCKMHB_03130	3.73e-159	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HEOCKMHB_03131	1.48e-23	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_03132	6.56e-74	-	-	-	L	-	-	-	PFAM Restriction endonuclease BamHI
HEOCKMHB_03133	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HEOCKMHB_03134	1.47e-86	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HEOCKMHB_03135	3.53e-69	yusN	-	-	M	-	-	-	Coat F domain
HEOCKMHB_03136	7.03e-53	-	-	-	-	-	-	-	-
HEOCKMHB_03137	6.69e-209	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEOCKMHB_03138	1.72e-10	-	-	-	S	-	-	-	YuzL-like protein
HEOCKMHB_03139	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HEOCKMHB_03140	3.02e-275	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HEOCKMHB_03141	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEOCKMHB_03142	4.13e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HEOCKMHB_03143	1.19e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEOCKMHB_03144	2.99e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HEOCKMHB_03145	5.93e-30	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HEOCKMHB_03146	2.25e-70	yusE	-	-	CO	-	-	-	Thioredoxin
HEOCKMHB_03147	5.08e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HEOCKMHB_03148	1.51e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEOCKMHB_03149	3.3e-135	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HEOCKMHB_03150	2.88e-183	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HEOCKMHB_03151	2.97e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEOCKMHB_03153	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEOCKMHB_03154	1.75e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HEOCKMHB_03155	3.01e-294	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEOCKMHB_03156	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HEOCKMHB_03157	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HEOCKMHB_03158	3.02e-191	-	-	-	S	-	-	-	Pfam:Arm-DNA-bind_4
HEOCKMHB_03159	1.98e-70	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HEOCKMHB_03160	3.84e-70	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEOCKMHB_03161	2.73e-26	-	-	-	-	-	-	-	-
HEOCKMHB_03162	1.05e-40	-	-	-	-	-	-	-	-
HEOCKMHB_03164	1.14e-44	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HEOCKMHB_03166	1.52e-58	-	-	-	-	-	-	-	-
HEOCKMHB_03167	5.63e-16	-	-	-	-	-	-	-	-
HEOCKMHB_03168	4.06e-204	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HEOCKMHB_03170	5.24e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HEOCKMHB_03171	1.89e-08	-	-	-	-	-	-	-	-
HEOCKMHB_03172	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase A domain
HEOCKMHB_03174	0.0	-	-	-	L	-	-	-	Virulence-associated protein E
HEOCKMHB_03175	1.19e-20	-	-	-	S	-	-	-	VRR-NUC domain protein
HEOCKMHB_03176	2.16e-287	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
HEOCKMHB_03177	4.27e-64	-	-	-	-	-	-	-	-
HEOCKMHB_03179	4.02e-79	-	-	-	L	-	-	-	Terminase, small subunit
HEOCKMHB_03180	0.0	terL	-	-	S	-	-	-	Terminase
HEOCKMHB_03182	8.49e-220	-	-	-	S	-	-	-	portal protein
HEOCKMHB_03183	1.69e-95	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HEOCKMHB_03184	4.2e-161	-	-	-	S	-	-	-	capsid protein
HEOCKMHB_03185	2.56e-32	-	-	-	-	-	-	-	-
HEOCKMHB_03186	5.7e-11	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEOCKMHB_03187	1.05e-40	-	-	-	S	-	-	-	Phage head-tail joining protein
HEOCKMHB_03188	2.31e-46	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEOCKMHB_03190	1.62e-42	-	-	-	S	-	-	-	Phage tail tube protein
HEOCKMHB_03192	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HEOCKMHB_03193	5.64e-150	-	-	-	S	-	-	-	Phage tail protein
HEOCKMHB_03194	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEOCKMHB_03195	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEOCKMHB_03196	1.12e-188	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEOCKMHB_03199	7.85e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HEOCKMHB_03200	5.17e-88	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_03202	3.22e-63	-	-	-	-	-	-	-	-
HEOCKMHB_03203	2.79e-14	-	-	-	-	-	-	-	-
HEOCKMHB_03204	1.06e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEOCKMHB_03205	7.45e-94	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HEOCKMHB_03206	1.09e-128	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HEOCKMHB_03207	2.19e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HEOCKMHB_03208	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HEOCKMHB_03210	1.96e-27	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HEOCKMHB_03211	1.34e-95	-	-	-	-	-	-	-	-
HEOCKMHB_03213	8.02e-204	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEOCKMHB_03214	8.37e-232	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEOCKMHB_03215	4.58e-305	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HEOCKMHB_03216	7.16e-201	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEOCKMHB_03217	2.91e-199	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HEOCKMHB_03218	6.94e-202	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HEOCKMHB_03219	8.02e-171	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HEOCKMHB_03220	1.49e-252	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEOCKMHB_03221	3.33e-209	bsn	-	-	L	-	-	-	Ribonuclease
HEOCKMHB_03222	7.27e-285	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEOCKMHB_03223	2.55e-287	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEOCKMHB_03224	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_03225	6.3e-86	-	-	-	-	-	-	-	-
HEOCKMHB_03226	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HEOCKMHB_03227	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEOCKMHB_03228	2.23e-73	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HEOCKMHB_03229	7.05e-215	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HEOCKMHB_03230	5.58e-182	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEOCKMHB_03231	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEOCKMHB_03232	1.53e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HEOCKMHB_03233	1.26e-245	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HEOCKMHB_03234	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEOCKMHB_03235	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03236	3e-93	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HEOCKMHB_03237	1.18e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEOCKMHB_03238	1.07e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HEOCKMHB_03239	5.56e-244	yutH	-	-	S	-	-	-	Spore coat protein
HEOCKMHB_03240	1.37e-306	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HEOCKMHB_03241	3.65e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEOCKMHB_03242	2.22e-206	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEOCKMHB_03243	1.55e-70	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HEOCKMHB_03244	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HEOCKMHB_03245	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEOCKMHB_03246	2.61e-70	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03247	7.79e-262	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEOCKMHB_03248	1.61e-48	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HEOCKMHB_03249	2.57e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEOCKMHB_03250	1.46e-203	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEOCKMHB_03251	1.88e-80	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HEOCKMHB_03252	6e-167	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_03253	5.08e-55	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HEOCKMHB_03255	1.12e-37	-	-	-	S	-	-	-	Bacteriocin class IId cyclical uberolysin-like
HEOCKMHB_03257	1.41e-151	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEOCKMHB_03258	1.09e-86	-	-	-	CP	-	-	-	Membrane
HEOCKMHB_03259	1.57e-37	-	-	-	-	-	-	-	-
HEOCKMHB_03260	1.29e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEOCKMHB_03262	1.15e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HEOCKMHB_03263	3.83e-297	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEOCKMHB_03264	1.21e-45	yuiB	-	-	S	-	-	-	Putative membrane protein
HEOCKMHB_03265	2.23e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03266	1.37e-98	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HEOCKMHB_03267	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEOCKMHB_03268	1.11e-273	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HEOCKMHB_03269	4.35e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HEOCKMHB_03270	1.8e-152	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HEOCKMHB_03271	2.31e-198	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEOCKMHB_03272	5.34e-166	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_03273	7.09e-273	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEOCKMHB_03274	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HEOCKMHB_03275	5.68e-208	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HEOCKMHB_03276	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_03277	3.6e-42	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HEOCKMHB_03278	2.71e-165	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HEOCKMHB_03279	9.05e-258	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HEOCKMHB_03280	1.66e-288	yukF	-	-	QT	-	-	-	Transcriptional regulator
HEOCKMHB_03281	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HEOCKMHB_03282	8.78e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HEOCKMHB_03283	2.45e-261	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HEOCKMHB_03284	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEOCKMHB_03285	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HEOCKMHB_03286	4.27e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HEOCKMHB_03287	2.35e-159	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_03288	1.83e-123	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEOCKMHB_03289	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HEOCKMHB_03290	2.31e-232	yueF	-	-	S	-	-	-	transporter activity
HEOCKMHB_03291	4.3e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HEOCKMHB_03292	1.1e-50	yueH	-	-	S	-	-	-	YueH-like protein
HEOCKMHB_03293	4.96e-86	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEOCKMHB_03294	4.46e-132	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HEOCKMHB_03295	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEOCKMHB_03296	1.12e-285	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HEOCKMHB_03297	1.59e-62	yuzC	-	-	-	-	-	-	-
HEOCKMHB_03298	1.87e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HEOCKMHB_03299	5.91e-78	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HEOCKMHB_03301	1.19e-315	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_03302	1.34e-146	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEOCKMHB_03303	3.55e-77	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HEOCKMHB_03304	8.16e-77	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HEOCKMHB_03305	2.15e-49	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOCKMHB_03306	1.13e-97	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOCKMHB_03307	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOCKMHB_03308	1.42e-65	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOCKMHB_03309	8.6e-88	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEOCKMHB_03310	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEOCKMHB_03312	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEOCKMHB_03313	1.68e-232	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEOCKMHB_03314	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_03315	7.9e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HEOCKMHB_03316	3.8e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEOCKMHB_03317	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEOCKMHB_03318	2.08e-97	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HEOCKMHB_03319	5.95e-92	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03320	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HEOCKMHB_03321	2.6e-240	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HEOCKMHB_03322	2.44e-147	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HEOCKMHB_03323	4.14e-81	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HEOCKMHB_03324	5e-278	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_03325	1.89e-276	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEOCKMHB_03326	3.95e-51	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HEOCKMHB_03327	3.41e-192	yugF	-	-	I	-	-	-	Hydrolase
HEOCKMHB_03328	1.53e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03329	2.28e-264	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HEOCKMHB_03330	6.83e-81	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEOCKMHB_03331	1.28e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HEOCKMHB_03332	7.5e-283	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEOCKMHB_03333	8.85e-288	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HEOCKMHB_03334	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HEOCKMHB_03336	4.57e-90	yugN	-	-	S	-	-	-	YugN-like family
HEOCKMHB_03337	8.97e-227	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HEOCKMHB_03338	2.98e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HEOCKMHB_03339	3.56e-22	-	-	-	-	-	-	-	-
HEOCKMHB_03340	1.95e-149	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HEOCKMHB_03341	1.82e-293	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEOCKMHB_03342	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEOCKMHB_03343	5.54e-236	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEOCKMHB_03344	1.82e-52	-	-	-	-	-	-	-	-
HEOCKMHB_03345	1.68e-174	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HEOCKMHB_03346	4.49e-285	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEOCKMHB_03347	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEOCKMHB_03348	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEOCKMHB_03349	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEOCKMHB_03350	4.02e-126	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HEOCKMHB_03351	4.84e-231	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEOCKMHB_03352	2.73e-248	yubA	-	-	S	-	-	-	transporter activity
HEOCKMHB_03353	7.33e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEOCKMHB_03355	2.58e-72	-	-	-	L	-	-	-	Arm DNA-binding domain
HEOCKMHB_03362	1.69e-65	-	-	-	K	-	-	-	BRO family, N-terminal domain
HEOCKMHB_03369	6.63e-10	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	COG1403 Restriction endonuclease
HEOCKMHB_03374	4.47e-68	-	-	-	L	-	-	-	Terminase, small subunit
HEOCKMHB_03375	9.42e-163	terL	-	-	S	-	-	-	Terminase
HEOCKMHB_03377	9.64e-183	-	-	-	S	-	-	-	portal protein
HEOCKMHB_03378	2.8e-68	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HEOCKMHB_03379	6.72e-130	-	-	-	S	-	-	-	capsid protein
HEOCKMHB_03381	1.41e-26	-	-	-	S	-	-	-	Phage head-tail joining protein
HEOCKMHB_03382	4.74e-43	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEOCKMHB_03387	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HEOCKMHB_03389	4.15e-125	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEOCKMHB_03390	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEOCKMHB_03391	3.63e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEOCKMHB_03394	1.64e-57	-	-	-	S	-	-	-	Bacteriophage holin family
HEOCKMHB_03395	2.05e-58	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HEOCKMHB_03397	2.74e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
HEOCKMHB_03398	2.56e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEOCKMHB_03399	1.71e-304	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HEOCKMHB_03400	4.3e-54	-	-	-	-	-	-	-	-
HEOCKMHB_03402	9.14e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEOCKMHB_03407	7.36e-20	-	-	-	-	-	-	-	-
HEOCKMHB_03408	2.15e-177	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HEOCKMHB_03411	2.17e-57	yjcN	-	-	-	-	-	-	-
HEOCKMHB_03412	2.36e-47	-	-	-	G	-	-	-	Cupin
HEOCKMHB_03413	6.24e-268	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEOCKMHB_03414	2.27e-185	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEOCKMHB_03415	1.97e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEOCKMHB_03416	4.6e-119	yuaB	-	-	-	-	-	-	-
HEOCKMHB_03417	9.65e-119	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HEOCKMHB_03418	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEOCKMHB_03419	9.64e-288	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEOCKMHB_03420	1.21e-134	-	-	-	S	-	-	-	MOSC domain
HEOCKMHB_03421	1.42e-102	yuaE	-	-	S	-	-	-	DinB superfamily
HEOCKMHB_03422	7.32e-105	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HEOCKMHB_03423	1.38e-273	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HEOCKMHB_03424	3.55e-118	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HEOCKMHB_03425	1.09e-174	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HEOCKMHB_03426	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HEOCKMHB_03427	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
HEOCKMHB_03428	4.58e-247	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEOCKMHB_03429	4.3e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_03430	2.28e-99	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HEOCKMHB_03431	4.46e-179	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HEOCKMHB_03432	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HEOCKMHB_03433	3.79e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEOCKMHB_03434	3.42e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEOCKMHB_03435	8.86e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOCKMHB_03436	1.06e-184	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOCKMHB_03437	6.9e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEOCKMHB_03438	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HEOCKMHB_03439	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOCKMHB_03440	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEOCKMHB_03441	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEOCKMHB_03442	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HEOCKMHB_03443	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEOCKMHB_03444	3.16e-180	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEOCKMHB_03445	2.94e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEOCKMHB_03446	1.82e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEOCKMHB_03447	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEOCKMHB_03448	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HEOCKMHB_03449	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEOCKMHB_03450	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEOCKMHB_03451	1.75e-118	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEOCKMHB_03452	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEOCKMHB_03453	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEOCKMHB_03454	2.58e-120	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEOCKMHB_03455	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEOCKMHB_03456	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEOCKMHB_03457	1.92e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEOCKMHB_03458	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HEOCKMHB_03459	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEOCKMHB_03460	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEOCKMHB_03461	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEOCKMHB_03462	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEOCKMHB_03463	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEOCKMHB_03464	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEOCKMHB_03465	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HEOCKMHB_03466	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEOCKMHB_03467	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HEOCKMHB_03468	3.62e-220	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HEOCKMHB_03469	9.55e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEOCKMHB_03470	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEOCKMHB_03471	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEOCKMHB_03472	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEOCKMHB_03473	9.87e-45	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HEOCKMHB_03474	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOCKMHB_03475	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEOCKMHB_03476	2.53e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HEOCKMHB_03477	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEOCKMHB_03478	6.68e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEOCKMHB_03479	2.04e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEOCKMHB_03480	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEOCKMHB_03481	6.9e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEOCKMHB_03482	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEOCKMHB_03483	4.65e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HEOCKMHB_03484	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HEOCKMHB_03485	9.69e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEOCKMHB_03486	9.32e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEOCKMHB_03487	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEOCKMHB_03488	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HEOCKMHB_03489	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEOCKMHB_03490	1.23e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEOCKMHB_03491	1.61e-156	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEOCKMHB_03492	1.85e-245	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HEOCKMHB_03493	1.22e-247	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEOCKMHB_03494	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEOCKMHB_03495	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HEOCKMHB_03496	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEOCKMHB_03497	8.58e-79	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HEOCKMHB_03498	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HEOCKMHB_03499	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_03500	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEOCKMHB_03501	1.14e-175	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HEOCKMHB_03502	5.89e-314	-	-	-	E	-	-	-	Aminotransferase class I and II
HEOCKMHB_03503	5.87e-155	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HEOCKMHB_03504	1.12e-137	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HEOCKMHB_03505	1.32e-167	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEOCKMHB_03506	5.85e-152	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEOCKMHB_03507	1.41e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEOCKMHB_03508	2.91e-197	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HEOCKMHB_03509	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEOCKMHB_03510	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEOCKMHB_03511	4.77e-76	yclD	-	-	-	-	-	-	-
HEOCKMHB_03512	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HEOCKMHB_03513	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HEOCKMHB_03515	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEOCKMHB_03516	2.66e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HEOCKMHB_03517	4.89e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HEOCKMHB_03518	2.46e-315	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_03519	2.47e-117	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEOCKMHB_03520	2.27e-176	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEOCKMHB_03521	1.22e-147	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEOCKMHB_03522	4.6e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_03523	7.36e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HEOCKMHB_03524	1.72e-303	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HEOCKMHB_03525	1.23e-153	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HEOCKMHB_03526	4.84e-300	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HEOCKMHB_03527	2.5e-162	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEOCKMHB_03528	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HEOCKMHB_03529	4.37e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEOCKMHB_03532	1.03e-314	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEOCKMHB_03533	1.06e-208	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03534	1.4e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03535	1.55e-173	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_03536	1.67e-220	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HEOCKMHB_03537	8.06e-313	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HEOCKMHB_03538	4.78e-192	ycnC	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03539	2.68e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HEOCKMHB_03540	2.79e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HEOCKMHB_03541	1.08e-67	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEOCKMHB_03542	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOCKMHB_03543	3.02e-278	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOCKMHB_03544	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEOCKMHB_03545	3.93e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HEOCKMHB_03546	3.14e-182	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_03547	6.58e-128	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03548	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HEOCKMHB_03549	1.15e-135	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEOCKMHB_03550	2.18e-69	-	-	-	-	-	-	-	-
HEOCKMHB_03551	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEOCKMHB_03552	1.96e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEOCKMHB_03553	2.79e-255	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEOCKMHB_03554	4.09e-78	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HEOCKMHB_03556	2.59e-175	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEOCKMHB_03557	8.23e-170	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HEOCKMHB_03558	6.98e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEOCKMHB_03559	3.25e-181	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HEOCKMHB_03560	1.68e-168	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HEOCKMHB_03561	5.16e-226	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HEOCKMHB_03562	7.07e-162	kipR	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03563	9.77e-144	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HEOCKMHB_03565	6.7e-72	yczJ	-	-	S	-	-	-	biosynthesis
HEOCKMHB_03566	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HEOCKMHB_03567	7.28e-212	ycsN	-	-	S	-	-	-	Oxidoreductase
HEOCKMHB_03568	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HEOCKMHB_03569	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HEOCKMHB_03570	6.33e-182	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEOCKMHB_03571	1.08e-122	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HEOCKMHB_03572	1.58e-146	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEOCKMHB_03573	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
HEOCKMHB_03574	9.89e-174	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEOCKMHB_03575	2.67e-62	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HEOCKMHB_03576	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEOCKMHB_03577	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEOCKMHB_03578	7.77e-240	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEOCKMHB_03579	4.73e-183	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HEOCKMHB_03580	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HEOCKMHB_03581	1.2e-298	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HEOCKMHB_03582	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEOCKMHB_03583	0.0	ydaO	-	-	E	-	-	-	amino acid
HEOCKMHB_03584	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEOCKMHB_03585	5.03e-80	-	-	-	K	-	-	-	acetyltransferase
HEOCKMHB_03586	1.49e-100	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEOCKMHB_03587	1.04e-83	-	-	-	-	-	-	-	-
HEOCKMHB_03588	1.77e-235	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HEOCKMHB_03591	1.06e-53	-	-	-	-	-	-	-	-
HEOCKMHB_03592	1.47e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEOCKMHB_03595	4.61e-44	ydaT	-	-	-	-	-	-	-
HEOCKMHB_03596	6.73e-97	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HEOCKMHB_03597	2.83e-63	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HEOCKMHB_03598	6.45e-174	ydbA	-	-	P	-	-	-	EcsC protein family
HEOCKMHB_03599	1.04e-75	ydbB	-	-	G	-	-	-	Cupin domain
HEOCKMHB_03600	6.59e-76	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HEOCKMHB_03601	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HEOCKMHB_03602	8.49e-52	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEOCKMHB_03603	2.07e-171	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEOCKMHB_03604	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEOCKMHB_03605	2.66e-146	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEOCKMHB_03606	3.75e-285	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOCKMHB_03607	1.85e-225	ydbI	-	-	S	-	-	-	AI-2E family transporter
HEOCKMHB_03608	1.79e-216	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEOCKMHB_03609	5.5e-164	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEOCKMHB_03610	1.32e-69	ydbL	-	-	-	-	-	-	-
HEOCKMHB_03611	7.84e-256	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HEOCKMHB_03612	2.36e-17	-	-	-	S	-	-	-	Fur-regulated basic protein B
HEOCKMHB_03613	6.11e-15	-	-	-	S	-	-	-	Fur-regulated basic protein A
HEOCKMHB_03614	1.34e-158	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOCKMHB_03615	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HEOCKMHB_03616	7.23e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HEOCKMHB_03617	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEOCKMHB_03618	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEOCKMHB_03619	6.7e-93	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HEOCKMHB_03620	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HEOCKMHB_03621	8.15e-136	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HEOCKMHB_03622	4.96e-72	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEOCKMHB_03623	1.18e-230	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HEOCKMHB_03624	3.01e-274	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEOCKMHB_03625	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEOCKMHB_03626	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HEOCKMHB_03627	9.89e-176	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HEOCKMHB_03628	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HEOCKMHB_03629	5.79e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEOCKMHB_03630	4.02e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HEOCKMHB_03631	1.34e-68	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HEOCKMHB_03632	6.83e-109	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEOCKMHB_03633	2.67e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEOCKMHB_03634	3.58e-135	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HEOCKMHB_03635	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HEOCKMHB_03636	1.78e-21	-	-	-	-	-	-	-	-
HEOCKMHB_03637	4.1e-74	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HEOCKMHB_03645	5.14e-10	-	-	-	S	-	-	-	YvrJ protein family
HEOCKMHB_03646	4.24e-62	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEOCKMHB_03650	4.65e-40	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HEOCKMHB_03653	6.4e-31	-	-	-	S	-	-	-	YesK-like protein
HEOCKMHB_03654	1.31e-246	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEOCKMHB_03655	9.84e-80	-	-	-	E	-	-	-	Pfam:DUF955
HEOCKMHB_03656	4.29e-71	-	-	-	K	-	-	-	Transcriptional
HEOCKMHB_03657	2.18e-34	-	-	-	-	-	-	-	-
HEOCKMHB_03659	1.87e-50	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HEOCKMHB_03661	1.56e-302	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
HEOCKMHB_03662	7.64e-231	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HEOCKMHB_03666	8.19e-49	yddA	-	-	-	-	-	-	-
HEOCKMHB_03670	7.38e-165	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
HEOCKMHB_03671	2.72e-33	yddC	-	-	-	-	-	-	-
HEOCKMHB_03672	1.85e-97	yddD	-	-	S	-	-	-	TcpE family
HEOCKMHB_03673	0.0	yddE	-	-	S	-	-	-	AAA-like domain
HEOCKMHB_03674	1.37e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
HEOCKMHB_03675	6.43e-261	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
HEOCKMHB_03676	1.46e-200	yddH	-	-	M	-	-	-	Lysozyme-like
HEOCKMHB_03677	1.89e-73	yddI	-	-	-	-	-	-	-
HEOCKMHB_03678	4.28e-47	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HEOCKMHB_03679	4.06e-75	-	-	-	-	-	-	-	-
HEOCKMHB_03683	1.41e-181	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HEOCKMHB_03684	7.54e-91	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEOCKMHB_03686	1.5e-65	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HEOCKMHB_03687	2.4e-253	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEOCKMHB_03688	7.99e-71	-	-	-	-	-	-	-	-
HEOCKMHB_03689	1.19e-99	-	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03690	7.03e-123	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEOCKMHB_03691	3.05e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HEOCKMHB_03692	2.64e-143	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEOCKMHB_03693	1e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HEOCKMHB_03694	6.49e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEOCKMHB_03695	1.99e-300	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOCKMHB_03696	3.96e-238	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HEOCKMHB_03697	1.41e-63	-	-	-	S	-	-	-	Patatin-like phospholipase
HEOCKMHB_03698	5.81e-57	-	-	-	S	-	-	-	Patatin-like phospholipase
HEOCKMHB_03700	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HEOCKMHB_03701	2.6e-90	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEOCKMHB_03702	8.48e-196	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HEOCKMHB_03703	3.58e-201	-	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_03704	1.19e-124	yrkC	-	-	G	-	-	-	Cupin domain
HEOCKMHB_03705	1.75e-106	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HEOCKMHB_03706	1.73e-186	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HEOCKMHB_03708	1.4e-238	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HEOCKMHB_03709	7.14e-63	ydeH	-	-	-	-	-	-	-
HEOCKMHB_03710	3.65e-206	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HEOCKMHB_03711	1.96e-252	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HEOCKMHB_03712	3.59e-78	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HEOCKMHB_03713	6.33e-278	nhaC_1	-	-	C	-	-	-	antiporter
HEOCKMHB_03714	1.34e-313	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HEOCKMHB_03715	1.74e-129	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_03716	1.41e-239	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HEOCKMHB_03717	2.13e-129	ydeS	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03718	2.99e-192	ydeK	-	-	EG	-	-	-	-transporter
HEOCKMHB_03719	1.8e-316	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEOCKMHB_03720	1.16e-62	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HEOCKMHB_03721	4.86e-33	yraE	-	-	-	ko:K06440	-	ko00000	-
HEOCKMHB_03722	3.27e-277	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEOCKMHB_03723	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
HEOCKMHB_03724	4.73e-47	yraG	-	-	-	ko:K06440	-	ko00000	-
HEOCKMHB_03725	6.26e-42	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HEOCKMHB_03726	3.37e-162	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HEOCKMHB_03727	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HEOCKMHB_03728	4.32e-117	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_03729	1.37e-188	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEOCKMHB_03730	3.1e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEOCKMHB_03731	4.16e-263	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEOCKMHB_03732	4.68e-280	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEOCKMHB_03733	7.19e-197	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_03734	1.05e-156	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEOCKMHB_03735	2.24e-101	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HEOCKMHB_03736	1.6e-181	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEOCKMHB_03737	3.72e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEOCKMHB_03738	1.15e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HEOCKMHB_03739	4.22e-132	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HEOCKMHB_03740	1.24e-208	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HEOCKMHB_03741	1.47e-144	ydhC	-	-	K	-	-	-	FCD
HEOCKMHB_03742	8.62e-69	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEOCKMHB_03743	1.11e-168	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEOCKMHB_03745	3.98e-311	pbpE	-	-	V	-	-	-	Beta-lactamase
HEOCKMHB_03747	5.02e-127	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HEOCKMHB_03748	1.24e-244	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HEOCKMHB_03749	3.82e-167	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HEOCKMHB_03750	1.12e-145	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HEOCKMHB_03751	1.35e-264	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HEOCKMHB_03752	2.88e-63	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HEOCKMHB_03753	4.14e-63	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEOCKMHB_03754	1.07e-128	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HEOCKMHB_03755	0.0	ybeC	-	-	E	-	-	-	amino acid
HEOCKMHB_03756	4.74e-209	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HEOCKMHB_03757	2.82e-110	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HEOCKMHB_03758	7.98e-228	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HEOCKMHB_03759	4.86e-313	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEOCKMHB_03762	2.1e-270	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HEOCKMHB_03763	1.22e-311	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEOCKMHB_03764	1.75e-227	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HEOCKMHB_03765	1.33e-254	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEOCKMHB_03766	7.16e-284	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEOCKMHB_03767	1.35e-216	ybaS	-	-	S	-	-	-	Na -dependent transporter
HEOCKMHB_03768	4.92e-130	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEOCKMHB_03769	9.92e-223	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03770	1.48e-224	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEOCKMHB_03771	1.12e-215	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HEOCKMHB_03772	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HEOCKMHB_03773	4.44e-291	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03774	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HEOCKMHB_03775	6.18e-300	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HEOCKMHB_03776	2.44e-302	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEOCKMHB_03777	5.23e-205	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEOCKMHB_03778	1.13e-76	ybbJ	-	-	J	-	-	-	acetyltransferase
HEOCKMHB_03779	5.95e-96	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HEOCKMHB_03785	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_03786	1.99e-145	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEOCKMHB_03787	3.01e-186	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEOCKMHB_03788	1.1e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03789	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEOCKMHB_03790	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEOCKMHB_03791	1.17e-21	-	-	-	S	-	-	-	peptidyl-tyrosine sulfation
HEOCKMHB_03792	2.6e-220	-	-	-	O	-	-	-	growth
HEOCKMHB_03793	5.91e-68	-	-	-	S	-	-	-	ABC-2 family transporter protein
HEOCKMHB_03794	3.07e-124	ybdN	-	-	-	-	-	-	-
HEOCKMHB_03795	9.57e-165	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HEOCKMHB_03796	2.34e-203	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HEOCKMHB_03797	3.49e-134	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HEOCKMHB_03798	6.65e-66	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HEOCKMHB_03799	1.27e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_03800	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_03801	1.67e-119	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HEOCKMHB_03802	6.05e-227	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
HEOCKMHB_03803	1.58e-129	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HEOCKMHB_03804	2.13e-205	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HEOCKMHB_03805	1.12e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HEOCKMHB_03806	7.69e-229	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HEOCKMHB_03807	6.5e-33	-	-	-	-	-	-	-	-
HEOCKMHB_03808	1.31e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HEOCKMHB_03809	7.13e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HEOCKMHB_03810	2.99e-136	yqeB	-	-	-	-	-	-	-
HEOCKMHB_03811	2.17e-52	ybyB	-	-	-	-	-	-	-
HEOCKMHB_03812	0.0	ybeC	-	-	E	-	-	-	amino acid
HEOCKMHB_03813	1.8e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HEOCKMHB_03814	2.63e-209	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HEOCKMHB_03815	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HEOCKMHB_03816	1e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HEOCKMHB_03817	1.12e-261	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HEOCKMHB_03819	1.14e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEOCKMHB_03820	5.91e-239	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEOCKMHB_03821	6.7e-264	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEOCKMHB_03822	9.04e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEOCKMHB_03823	3.37e-110	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_03824	4.85e-191	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEOCKMHB_03825	9.76e-52	ybfN	-	-	-	-	-	-	-
HEOCKMHB_03826	4.36e-240	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HEOCKMHB_03827	2.61e-266	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEOCKMHB_03828	5.77e-246	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEOCKMHB_03829	7.12e-303	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEOCKMHB_03830	4.63e-225	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HEOCKMHB_03831	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEOCKMHB_03832	7.21e-90	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEOCKMHB_03833	4.31e-44	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEOCKMHB_03834	2.63e-264	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEOCKMHB_03835	2.43e-197	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HEOCKMHB_03836	2.31e-158	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HEOCKMHB_03837	3.3e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HEOCKMHB_03838	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEOCKMHB_03839	3.53e-118	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HEOCKMHB_03840	5.44e-229	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEOCKMHB_03841	1.89e-82	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HEOCKMHB_03842	3.11e-73	ydfQ	-	-	CO	-	-	-	Thioredoxin
HEOCKMHB_03843	2.08e-15	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HEOCKMHB_03844	4.68e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEOCKMHB_03845	5.22e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HEOCKMHB_03846	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HEOCKMHB_03847	8.68e-36	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEOCKMHB_03848	1.44e-155	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEOCKMHB_03849	1.99e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEOCKMHB_03850	3.41e-241	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HEOCKMHB_03851	1.47e-305	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEOCKMHB_03852	3.35e-125	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEOCKMHB_03853	1.19e-58	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEOCKMHB_03854	5.9e-21	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEOCKMHB_03855	1.21e-245	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HEOCKMHB_03856	6.43e-211	yccK	-	-	C	-	-	-	Aldo keto reductase
HEOCKMHB_03857	1.13e-210	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HEOCKMHB_03858	4.33e-301	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_03859	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEOCKMHB_03860	1.31e-114	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEOCKMHB_03861	3.74e-221	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HEOCKMHB_03862	6.52e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HEOCKMHB_03863	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEOCKMHB_03864	1.5e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
HEOCKMHB_03865	1.86e-62	-	-	-	K	-	-	-	Virulence activator alpha C-term
HEOCKMHB_03866	5.72e-214	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEOCKMHB_03867	1.15e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEOCKMHB_03868	1.38e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEOCKMHB_03869	8.68e-231	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_03870	9.56e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HEOCKMHB_03871	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEOCKMHB_03872	3.36e-136	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEOCKMHB_03873	4.28e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HEOCKMHB_03874	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HEOCKMHB_03875	3.9e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HEOCKMHB_03876	2.43e-265	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HEOCKMHB_03878	8.61e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HEOCKMHB_03879	2.01e-184	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEOCKMHB_03880	4.54e-207	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEOCKMHB_03881	6.41e-261	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HEOCKMHB_03882	2.88e-238	ycgA	-	-	S	-	-	-	Membrane
HEOCKMHB_03883	4.22e-33	ycgA	-	-	S	-	-	-	Membrane
HEOCKMHB_03884	5.14e-54	ycgB	-	-	-	-	-	-	-
HEOCKMHB_03885	2.85e-15	-	-	-	S	-	-	-	RDD family
HEOCKMHB_03886	1.55e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEOCKMHB_03887	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HEOCKMHB_03888	3.16e-97	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEOCKMHB_03890	1.15e-54	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HEOCKMHB_03891	6.64e-76	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HEOCKMHB_03892	5.9e-183	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HEOCKMHB_03893	2.03e-305	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEOCKMHB_03894	6.25e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HEOCKMHB_03895	2.05e-188	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEOCKMHB_03896	1.69e-164	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HEOCKMHB_03897	1.47e-121	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_03898	6.16e-148	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEOCKMHB_03899	1.43e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEOCKMHB_03900	9.05e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HEOCKMHB_03901	8.28e-178	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HEOCKMHB_03902	1.53e-213	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEOCKMHB_03903	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEOCKMHB_03904	6.09e-149	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOCKMHB_03905	8.21e-147	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEOCKMHB_03906	1.78e-284	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HEOCKMHB_03907	4.86e-235	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HEOCKMHB_03908	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEOCKMHB_03909	1.64e-72	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HEOCKMHB_03910	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEOCKMHB_03911	1.41e-49	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEOCKMHB_03912	9.85e-281	yciC	-	-	S	-	-	-	GTPases (G3E family)
HEOCKMHB_03913	7.5e-278	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEOCKMHB_03914	3.65e-94	yckC	-	-	S	-	-	-	membrane
HEOCKMHB_03915	7.52e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HEOCKMHB_03916	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEOCKMHB_03917	7.34e-86	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HEOCKMHB_03918	2.67e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEOCKMHB_03919	7.04e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HEOCKMHB_03920	6.52e-132	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HEOCKMHB_03921	2.89e-84	hxlR	-	-	K	-	-	-	transcriptional
HEOCKMHB_03925	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HEOCKMHB_03926	8.33e-230	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEOCKMHB_03927	9.99e-39	yazB	-	-	K	-	-	-	transcriptional
HEOCKMHB_03928	4.38e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEOCKMHB_03929	1.88e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEOCKMHB_03930	1.62e-196	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEOCKMHB_03931	3.18e-191	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HEOCKMHB_03932	5.14e-137	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HEOCKMHB_03933	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEOCKMHB_03934	1.79e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEOCKMHB_03935	1.22e-192	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HEOCKMHB_03936	7.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEOCKMHB_03937	5.46e-186	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEOCKMHB_03938	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEOCKMHB_03939	4.29e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEOCKMHB_03940	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEOCKMHB_03941	1.18e-229	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEOCKMHB_03942	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEOCKMHB_03943	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HEOCKMHB_03946	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEOCKMHB_03947	2.42e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HEOCKMHB_03948	1.47e-128	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HEOCKMHB_03949	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HEOCKMHB_03950	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEOCKMHB_03951	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEOCKMHB_03952	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEOCKMHB_03953	1.09e-116	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HEOCKMHB_03954	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEOCKMHB_03955	5.24e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HEOCKMHB_03956	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEOCKMHB_03957	1.4e-133	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEOCKMHB_03958	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEOCKMHB_03959	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEOCKMHB_03960	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEOCKMHB_03961	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HEOCKMHB_03962	5.43e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HEOCKMHB_03963	2.25e-205	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEOCKMHB_03964	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HEOCKMHB_03965	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03966	1.46e-186	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HEOCKMHB_03967	9.41e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEOCKMHB_03968	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEOCKMHB_03969	3.55e-288	yabE	-	-	T	-	-	-	protein conserved in bacteria
HEOCKMHB_03970	1.44e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HEOCKMHB_03971	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEOCKMHB_03972	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HEOCKMHB_03973	9.82e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEOCKMHB_03974	1.64e-62	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HEOCKMHB_03975	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HEOCKMHB_03976	2.53e-55	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HEOCKMHB_03977	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HEOCKMHB_03978	8.67e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEOCKMHB_03979	2.86e-92	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HEOCKMHB_03980	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HEOCKMHB_03981	7.14e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEOCKMHB_03982	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HEOCKMHB_03983	6.32e-226	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HEOCKMHB_03984	1.05e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEOCKMHB_03985	3.55e-39	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HEOCKMHB_03986	2.16e-48	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HEOCKMHB_03987	7.67e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HEOCKMHB_03988	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEOCKMHB_03989	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEOCKMHB_03990	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEOCKMHB_03991	5.61e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEOCKMHB_03992	4.62e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HEOCKMHB_03993	8.84e-272	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HEOCKMHB_03994	3.32e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HEOCKMHB_03995	1.4e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HEOCKMHB_03997	2.36e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HEOCKMHB_03998	4.16e-281	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEOCKMHB_03999	2.35e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEOCKMHB_04000	7.47e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEOCKMHB_04001	1.03e-315	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEOCKMHB_04002	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEOCKMHB_04003	1.64e-224	yaaC	-	-	S	-	-	-	YaaC-like Protein
HEOCKMHB_04004	1.2e-147	yoxB	-	-	-	-	-	-	-
HEOCKMHB_04005	1.23e-49	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEOCKMHB_04006	4.03e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEOCKMHB_04007	6.69e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEOCKMHB_04008	5.78e-173	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEOCKMHB_04009	3.37e-251	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEOCKMHB_04010	7.74e-201	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HEOCKMHB_04011	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HEOCKMHB_04012	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEOCKMHB_04013	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEOCKMHB_04014	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HEOCKMHB_04015	5.29e-237	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HEOCKMHB_04016	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEOCKMHB_04017	7.83e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HEOCKMHB_04018	7.69e-123	-	-	-	L	-	-	-	Integrase
HEOCKMHB_04020	8.33e-122	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HEOCKMHB_04021	1.31e-305	yoeA	-	-	V	-	-	-	MATE efflux family protein
HEOCKMHB_04022	1.56e-229	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HEOCKMHB_04023	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEOCKMHB_04024	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_04025	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HEOCKMHB_04026	9.31e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEOCKMHB_04027	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HEOCKMHB_04028	6.97e-264	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEOCKMHB_04029	5.24e-43	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOCKMHB_04030	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEOCKMHB_04031	1.6e-304	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HEOCKMHB_04032	2.28e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HEOCKMHB_04033	2.16e-208	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HEOCKMHB_04034	2.54e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HEOCKMHB_04035	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEOCKMHB_04036	6.22e-134	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HEOCKMHB_04037	1.01e-196	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEOCKMHB_04038	1.02e-88	yngA	-	-	S	-	-	-	membrane
HEOCKMHB_04039	8.22e-171	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEOCKMHB_04040	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEOCKMHB_04041	3.12e-254	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEOCKMHB_04042	7.37e-158	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEOCKMHB_04043	4.21e-242	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEOCKMHB_04044	6.2e-207	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEOCKMHB_04045	2.32e-145	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEOCKMHB_04046	5.28e-135	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEOCKMHB_04047	3.62e-156	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEOCKMHB_04048	3.84e-262	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEOCKMHB_04049	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_04050	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_04051	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEOCKMHB_04052	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HEOCKMHB_04053	4.05e-303	-	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HEOCKMHB_04054	7.49e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEOCKMHB_04055	3.49e-282	-	-	-	T	-	-	-	Histidine kinase
HEOCKMHB_04056	2.03e-67	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HEOCKMHB_04057	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HEOCKMHB_04058	2.24e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HEOCKMHB_04059	1.56e-28	yndG	-	-	S	-	-	-	DoxX-like family
HEOCKMHB_04060	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEOCKMHB_04061	2.04e-60	ynfC	-	-	-	-	-	-	-
HEOCKMHB_04062	2.21e-19	-	-	-	-	-	-	-	-
HEOCKMHB_04063	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOCKMHB_04064	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEOCKMHB_04065	1.41e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HEOCKMHB_04066	1.51e-119	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEOCKMHB_04067	9.38e-58	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HEOCKMHB_04068	5.95e-65	yneQ	-	-	-	-	-	-	-
HEOCKMHB_04069	8.11e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HEOCKMHB_04070	4.08e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HEOCKMHB_04072	4.36e-114	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEOCKMHB_04073	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEOCKMHB_04074	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HEOCKMHB_04075	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HEOCKMHB_04076	2.64e-77	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HEOCKMHB_04077	4.28e-92	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HEOCKMHB_04078	7.59e-97	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HEOCKMHB_04079	4.11e-75	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HEOCKMHB_04080	1.38e-158	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HEOCKMHB_04081	8.06e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEOCKMHB_04082	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HEOCKMHB_04083	3.48e-103	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HEOCKMHB_04084	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEOCKMHB_04085	2.33e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HEOCKMHB_04086	4.8e-141	yneB	-	-	L	-	-	-	resolvase
HEOCKMHB_04087	4.8e-66	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEOCKMHB_04088	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEOCKMHB_04090	2.23e-86	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEOCKMHB_04091	4.95e-182	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEOCKMHB_04092	4.12e-10	-	-	-	-	-	-	-	-
HEOCKMHB_04093	2.53e-162	yndL	-	-	S	-	-	-	Replication protein
HEOCKMHB_04094	3.99e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HEOCKMHB_04095	9.69e-99	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HEOCKMHB_04096	1.33e-43	-	-	-	S	-	-	-	TM2 domain
HEOCKMHB_04097	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HEOCKMHB_04099	1.97e-119	yvgO	-	-	-	-	-	-	-
HEOCKMHB_04100	9.32e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEOCKMHB_04101	3.2e-150	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HEOCKMHB_04102	1.34e-238	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEOCKMHB_04103	2.39e-130	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HEOCKMHB_04105	1.87e-53	-	-	-	-	-	-	-	-
HEOCKMHB_04107	1.09e-117	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEOCKMHB_04108	1.52e-164	yoaP	-	-	K	-	-	-	YoaP-like
HEOCKMHB_04109	1.69e-13	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEOCKMHB_04110	1.95e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HEOCKMHB_04111	2.04e-10	-	-	-	-	-	-	-	-
HEOCKMHB_04112	5.82e-16	-	-	-	-	-	-	-	-
HEOCKMHB_04113	1.82e-231	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEOCKMHB_04114	1.08e-86	dinB	-	-	S	-	-	-	DinB family
HEOCKMHB_04116	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEOCKMHB_04129	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall