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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MPHLCAIF_00001	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MPHLCAIF_00002	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00003	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MPHLCAIF_00004	2.43e-58	yjcN	-	-	-	-	-	-	-
MPHLCAIF_00005	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MPHLCAIF_00006	2.49e-07	-	-	-	-	-	-	-	-
MPHLCAIF_00007	2.28e-25	-	-	-	-	-	-	-	-
MPHLCAIF_00008	1.92e-47	-	-	-	-	-	-	-	-
MPHLCAIF_00012	2.51e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_00014	6.79e-11	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
MPHLCAIF_00016	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MPHLCAIF_00017	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MPHLCAIF_00018	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MPHLCAIF_00019	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MPHLCAIF_00020	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_00021	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MPHLCAIF_00022	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MPHLCAIF_00023	2.21e-94	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_00025	4.23e-287	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
MPHLCAIF_00027	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPHLCAIF_00028	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
MPHLCAIF_00029	2.22e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MPHLCAIF_00030	2.63e-77	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MPHLCAIF_00031	6.8e-250	yqkA	-	-	K	-	-	-	GrpB protein
MPHLCAIF_00032	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MPHLCAIF_00033	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MPHLCAIF_00034	4.61e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MPHLCAIF_00035	8.04e-27	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MPHLCAIF_00036	3.61e-215	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MPHLCAIF_00037	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MPHLCAIF_00038	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MPHLCAIF_00039	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
MPHLCAIF_00040	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00041	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MPHLCAIF_00042	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MPHLCAIF_00043	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MPHLCAIF_00044	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MPHLCAIF_00045	1.47e-41	yqkK	-	-	-	-	-	-	-
MPHLCAIF_00046	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MPHLCAIF_00047	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MPHLCAIF_00048	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MPHLCAIF_00049	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MPHLCAIF_00050	2.28e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MPHLCAIF_00051	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MPHLCAIF_00052	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MPHLCAIF_00053	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MPHLCAIF_00054	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MPHLCAIF_00055	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_00056	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MPHLCAIF_00057	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MPHLCAIF_00058	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MPHLCAIF_00059	1.21e-245	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MPHLCAIF_00060	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MPHLCAIF_00061	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MPHLCAIF_00062	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MPHLCAIF_00063	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MPHLCAIF_00064	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
MPHLCAIF_00065	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MPHLCAIF_00066	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MPHLCAIF_00071	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_00073	1.82e-55	-	-	-	-	-	-	-	-
MPHLCAIF_00074	7.74e-301	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MPHLCAIF_00075	8.22e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MPHLCAIF_00076	6.72e-171	-	-	-	M	-	-	-	Membrane
MPHLCAIF_00077	1.3e-38	yetM	-	-	CH	-	-	-	FAD binding domain
MPHLCAIF_00078	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MPHLCAIF_00079	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MPHLCAIF_00080	1.52e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MPHLCAIF_00081	3.28e-44	-	-	-	-	-	-	-	-
MPHLCAIF_00082	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_00083	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MPHLCAIF_00084	3.66e-157	yetF	-	-	S	-	-	-	membrane
MPHLCAIF_00085	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MPHLCAIF_00086	1.3e-207	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MPHLCAIF_00087	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MPHLCAIF_00088	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MPHLCAIF_00089	1.54e-213	yetA	-	-	-	-	-	-	-
MPHLCAIF_00090	5.02e-234	yetA	-	-	-	-	-	-	-
MPHLCAIF_00091	2.25e-127	yetA	-	-	-	-	-	-	-
MPHLCAIF_00092	2.97e-193	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MPHLCAIF_00093	8.37e-153	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MPHLCAIF_00094	2.73e-80	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MPHLCAIF_00095	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MPHLCAIF_00096	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MPHLCAIF_00097	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MPHLCAIF_00098	2.32e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MPHLCAIF_00099	1.07e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
MPHLCAIF_00100	5.05e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MPHLCAIF_00101	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00102	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MPHLCAIF_00103	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MPHLCAIF_00104	1.17e-217	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MPHLCAIF_00105	7.99e-312	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MPHLCAIF_00106	2.41e-199	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MPHLCAIF_00107	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_00108	6.29e-133	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
MPHLCAIF_00109	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MPHLCAIF_00110	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MPHLCAIF_00111	9.4e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MPHLCAIF_00112	1.55e-59	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MPHLCAIF_00113	9.52e-128	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_00115	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MPHLCAIF_00117	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
MPHLCAIF_00118	1.06e-73	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
MPHLCAIF_00119	1.25e-123	-	3.4.24.40	-	CO	ko:K01406	ko01503,map01503	ko00000,ko00001,ko01000,ko01002	amine dehydrogenase activity
MPHLCAIF_00120	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MPHLCAIF_00121	1.41e-72	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MPHLCAIF_00123	0.0	-	-	-	K	-	-	-	SIR2-like domain
MPHLCAIF_00124	1.14e-27	-	-	-	-	-	-	-	-
MPHLCAIF_00125	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPHLCAIF_00126	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MPHLCAIF_00127	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MPHLCAIF_00128	6.97e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00129	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPHLCAIF_00130	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MPHLCAIF_00131	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MPHLCAIF_00132	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPHLCAIF_00133	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MPHLCAIF_00134	3.49e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MPHLCAIF_00135	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MPHLCAIF_00136	5.71e-121	-	-	-	M	-	-	-	FR47-like protein
MPHLCAIF_00137	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MPHLCAIF_00138	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MPHLCAIF_00139	6.53e-108	yuaE	-	-	S	-	-	-	DinB superfamily
MPHLCAIF_00140	3.92e-135	yuaD	-	-	-	-	-	-	-
MPHLCAIF_00141	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MPHLCAIF_00142	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MPHLCAIF_00143	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MPHLCAIF_00144	5.83e-118	yuaB	-	-	-	-	-	-	-
MPHLCAIF_00145	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MPHLCAIF_00146	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
MPHLCAIF_00147	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
MPHLCAIF_00148	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MPHLCAIF_00149	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MPHLCAIF_00150	5.39e-111	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
MPHLCAIF_00152	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MPHLCAIF_00153	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
MPHLCAIF_00154	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MPHLCAIF_00155	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MPHLCAIF_00156	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MPHLCAIF_00157	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MPHLCAIF_00158	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MPHLCAIF_00159	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MPHLCAIF_00160	2.61e-185	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00161	2.35e-115	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00162	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00163	2.23e-199	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00164	4.17e-63	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00165	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_00166	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MPHLCAIF_00167	2.04e-47	-	-	-	-	-	-	-	-
MPHLCAIF_00168	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MPHLCAIF_00169	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MPHLCAIF_00170	4.18e-299	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MPHLCAIF_00171	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MPHLCAIF_00172	2.16e-48	-	-	-	-	-	-	-	-
MPHLCAIF_00173	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MPHLCAIF_00174	8.37e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MPHLCAIF_00175	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
MPHLCAIF_00177	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MPHLCAIF_00178	1.26e-287	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MPHLCAIF_00179	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MPHLCAIF_00180	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MPHLCAIF_00181	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MPHLCAIF_00182	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MPHLCAIF_00183	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00184	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
MPHLCAIF_00185	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MPHLCAIF_00186	3.32e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MPHLCAIF_00187	4.32e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_00188	8.36e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MPHLCAIF_00189	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MPHLCAIF_00191	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_00192	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MPHLCAIF_00193	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00194	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MPHLCAIF_00195	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MPHLCAIF_00196	1.88e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MPHLCAIF_00197	2.24e-251	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MPHLCAIF_00198	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_00199	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MPHLCAIF_00200	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MPHLCAIF_00201	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MPHLCAIF_00202	1.42e-21	-	-	-	-	-	-	-	-
MPHLCAIF_00203	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MPHLCAIF_00204	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MPHLCAIF_00205	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MPHLCAIF_00206	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MPHLCAIF_00207	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MPHLCAIF_00208	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MPHLCAIF_00209	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MPHLCAIF_00210	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MPHLCAIF_00211	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_00212	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_00213	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
MPHLCAIF_00214	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MPHLCAIF_00215	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MPHLCAIF_00216	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MPHLCAIF_00217	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MPHLCAIF_00218	2.53e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MPHLCAIF_00219	1.07e-81	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPHLCAIF_00220	6.56e-107	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPHLCAIF_00221	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MPHLCAIF_00222	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MPHLCAIF_00223	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MPHLCAIF_00224	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MPHLCAIF_00225	7.67e-177	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MPHLCAIF_00226	2.93e-45	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_00227	4.37e-182	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_00228	2.65e-123	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MPHLCAIF_00229	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_00230	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_00231	3.53e-226	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MPHLCAIF_00232	3.94e-221	yccK	-	-	C	-	-	-	Aldo keto reductase
MPHLCAIF_00233	1.09e-254	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_00234	2.86e-77	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MPHLCAIF_00235	1.42e-77	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MPHLCAIF_00236	1.62e-161	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MPHLCAIF_00237	1.77e-43	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MPHLCAIF_00238	4.03e-156	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MPHLCAIF_00239	1.18e-253	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MPHLCAIF_00240	4.32e-78	-	-	-	S	-	-	-	RDD family
MPHLCAIF_00241	5.69e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MPHLCAIF_00242	8.37e-258	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MPHLCAIF_00243	4.42e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MPHLCAIF_00244	4.75e-307	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MPHLCAIF_00245	4.66e-257	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MPHLCAIF_00246	3.43e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MPHLCAIF_00247	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MPHLCAIF_00248	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MPHLCAIF_00249	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MPHLCAIF_00250	6.36e-173	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
MPHLCAIF_00251	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MPHLCAIF_00252	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MPHLCAIF_00253	1.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
MPHLCAIF_00254	5.55e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_00255	4.37e-214	ycbM	-	-	T	-	-	-	Histidine kinase
MPHLCAIF_00256	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_00257	4.05e-215	eamA1	-	-	EG	-	-	-	spore germination
MPHLCAIF_00258	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MPHLCAIF_00259	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MPHLCAIF_00260	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MPHLCAIF_00261	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MPHLCAIF_00262	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MPHLCAIF_00263	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00264	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MPHLCAIF_00265	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MPHLCAIF_00266	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MPHLCAIF_00267	5.88e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_00268	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MPHLCAIF_00269	2.97e-270	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MPHLCAIF_00270	2.77e-37	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MPHLCAIF_00271	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MPHLCAIF_00272	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MPHLCAIF_00273	1.25e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MPHLCAIF_00275	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MPHLCAIF_00276	1.01e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MPHLCAIF_00277	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00278	6.04e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MPHLCAIF_00279	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MPHLCAIF_00280	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_00281	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
MPHLCAIF_00282	2.25e-59	ybfN	-	-	-	-	-	-	-
MPHLCAIF_00283	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MPHLCAIF_00284	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MPHLCAIF_00285	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MPHLCAIF_00286	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MPHLCAIF_00288	1.69e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MPHLCAIF_00289	4.6e-271	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MPHLCAIF_00290	2.61e-73	-	-	-	-	-	-	-	-
MPHLCAIF_00291	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
MPHLCAIF_00292	3.63e-43	-	-	-	K	-	-	-	sigma factor activity
MPHLCAIF_00293	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MPHLCAIF_00294	1.06e-207	ybfH	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_00295	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MPHLCAIF_00298	6.21e-57	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00299	5.4e-184	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00300	8.65e-202	ybfA	-	-	K	-	-	-	FR47-like protein
MPHLCAIF_00301	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MPHLCAIF_00302	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MPHLCAIF_00303	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MPHLCAIF_00304	0.0	ybeC	-	-	E	-	-	-	amino acid
MPHLCAIF_00305	1.28e-37	ybyB	-	-	-	-	-	-	-
MPHLCAIF_00306	2.99e-311	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MPHLCAIF_00307	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MPHLCAIF_00308	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
MPHLCAIF_00309	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MPHLCAIF_00310	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_00311	8.98e-274	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
MPHLCAIF_00312	1.49e-192	ybdN	-	-	-	-	-	-	-
MPHLCAIF_00313	1.68e-179	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MPHLCAIF_00315	2.78e-219	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
MPHLCAIF_00316	1.55e-65	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
MPHLCAIF_00317	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MPHLCAIF_00318	1.6e-63	-	-	-	-	-	-	-	-
MPHLCAIF_00320	9.45e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
MPHLCAIF_00321	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
MPHLCAIF_00322	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MPHLCAIF_00323	1.29e-129	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MPHLCAIF_00324	6.2e-155	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MPHLCAIF_00325	9.34e-128	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MPHLCAIF_00326	5.87e-54	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MPHLCAIF_00327	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MPHLCAIF_00328	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MPHLCAIF_00329	1.6e-287	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00330	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MPHLCAIF_00331	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MPHLCAIF_00332	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_00338	4.19e-101	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MPHLCAIF_00339	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
MPHLCAIF_00340	1.92e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MPHLCAIF_00341	2.4e-190	ybbH	-	-	K	-	-	-	transcriptional
MPHLCAIF_00342	2.97e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00343	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MPHLCAIF_00344	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MPHLCAIF_00345	2.33e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00346	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MPHLCAIF_00347	2.54e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MPHLCAIF_00348	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00349	3.37e-226	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00350	7.76e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MPHLCAIF_00351	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
MPHLCAIF_00353	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MPHLCAIF_00354	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MPHLCAIF_00355	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MPHLCAIF_00356	1.28e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MPHLCAIF_00357	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00358	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
MPHLCAIF_00359	1.54e-215	gspA	-	-	M	-	-	-	General stress
MPHLCAIF_00360	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MPHLCAIF_00361	2.67e-308	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00362	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MPHLCAIF_00363	1.05e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MPHLCAIF_00364	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MPHLCAIF_00365	8.1e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MPHLCAIF_00366	1.9e-278	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MPHLCAIF_00367	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MPHLCAIF_00368	7.14e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
MPHLCAIF_00369	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MPHLCAIF_00370	4.47e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MPHLCAIF_00371	1.28e-201	ywbI	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00372	1.54e-183	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MPHLCAIF_00373	3e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MPHLCAIF_00374	5.68e-314	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MPHLCAIF_00375	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MPHLCAIF_00376	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MPHLCAIF_00377	1.26e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MPHLCAIF_00378	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPHLCAIF_00379	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MPHLCAIF_00381	1.98e-157	ywcC	-	-	K	-	-	-	transcriptional regulator
MPHLCAIF_00382	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MPHLCAIF_00383	5.34e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MPHLCAIF_00384	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MPHLCAIF_00385	5.11e-49	ydaS	-	-	S	-	-	-	membrane
MPHLCAIF_00386	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MPHLCAIF_00387	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MPHLCAIF_00388	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MPHLCAIF_00389	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MPHLCAIF_00390	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MPHLCAIF_00391	3.69e-260	-	-	-	S	-	-	-	Acetyltransferase
MPHLCAIF_00392	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MPHLCAIF_00393	2.31e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MPHLCAIF_00394	2.83e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPHLCAIF_00395	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MPHLCAIF_00397	5e-63	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MPHLCAIF_00398	6.46e-112	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MPHLCAIF_00399	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MPHLCAIF_00400	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00401	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MPHLCAIF_00402	6.19e-39	ywdA	-	-	-	-	-	-	-
MPHLCAIF_00403	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MPHLCAIF_00404	5.46e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MPHLCAIF_00405	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MPHLCAIF_00406	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MPHLCAIF_00407	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MPHLCAIF_00408	3.75e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
MPHLCAIF_00409	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
MPHLCAIF_00410	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MPHLCAIF_00411	7.76e-185	spsA	-	-	M	-	-	-	Spore Coat
MPHLCAIF_00412	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MPHLCAIF_00413	3.73e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MPHLCAIF_00414	1.41e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MPHLCAIF_00415	1.13e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MPHLCAIF_00416	1.09e-167	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MPHLCAIF_00417	5.73e-240	spsG	-	-	M	-	-	-	Spore Coat
MPHLCAIF_00418	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MPHLCAIF_00419	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MPHLCAIF_00420	1.92e-203	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MPHLCAIF_00421	3.73e-113	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MPHLCAIF_00422	2.14e-100	-	-	-	-	-	-	-	-
MPHLCAIF_00423	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MPHLCAIF_00424	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MPHLCAIF_00425	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MPHLCAIF_00426	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MPHLCAIF_00427	3.81e-275	ywfA	-	-	EGP	-	-	-	-transporter
MPHLCAIF_00428	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MPHLCAIF_00429	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MPHLCAIF_00430	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_00431	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MPHLCAIF_00432	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MPHLCAIF_00433	3.03e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MPHLCAIF_00434	1.95e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MPHLCAIF_00435	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MPHLCAIF_00436	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MPHLCAIF_00437	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_00438	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MPHLCAIF_00439	5.88e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MPHLCAIF_00440	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MPHLCAIF_00441	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MPHLCAIF_00442	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MPHLCAIF_00443	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
MPHLCAIF_00444	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00445	2.66e-307	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MPHLCAIF_00447	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MPHLCAIF_00448	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00449	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MPHLCAIF_00450	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
MPHLCAIF_00451	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
MPHLCAIF_00452	2.1e-64	-	-	-	-	-	-	-	-
MPHLCAIF_00453	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MPHLCAIF_00454	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MPHLCAIF_00455	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MPHLCAIF_00456	2.03e-84	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MPHLCAIF_00458	5.77e-100	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MPHLCAIF_00459	4.48e-273	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
MPHLCAIF_00460	1.18e-315	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MPHLCAIF_00462	7.39e-312	-	-	-	L	-	-	-	Peptidase, M16
MPHLCAIF_00463	4.01e-275	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
MPHLCAIF_00464	1.09e-293	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MPHLCAIF_00465	6.11e-169	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MPHLCAIF_00467	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
MPHLCAIF_00468	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
MPHLCAIF_00469	5.42e-95	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00470	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MPHLCAIF_00471	8.44e-274	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MPHLCAIF_00472	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MPHLCAIF_00473	1.84e-179	ywiC	-	-	S	-	-	-	YwiC-like protein
MPHLCAIF_00474	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MPHLCAIF_00475	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MPHLCAIF_00476	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MPHLCAIF_00477	2.77e-122	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MPHLCAIF_00478	8.39e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MPHLCAIF_00479	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MPHLCAIF_00480	9.8e-37	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MPHLCAIF_00481	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MPHLCAIF_00482	5.49e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MPHLCAIF_00483	1.4e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MPHLCAIF_00484	5.54e-286	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MPHLCAIF_00485	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MPHLCAIF_00486	2.01e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
MPHLCAIF_00487	8.03e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MPHLCAIF_00488	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MPHLCAIF_00489	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MPHLCAIF_00490	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MPHLCAIF_00491	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MPHLCAIF_00492	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MPHLCAIF_00494	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MPHLCAIF_00495	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MPHLCAIF_00496	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MPHLCAIF_00497	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MPHLCAIF_00498	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MPHLCAIF_00499	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MPHLCAIF_00500	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MPHLCAIF_00501	2.45e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MPHLCAIF_00502	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_00503	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MPHLCAIF_00504	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MPHLCAIF_00506	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MPHLCAIF_00507	2.29e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MPHLCAIF_00508	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MPHLCAIF_00509	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MPHLCAIF_00510	6.48e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MPHLCAIF_00511	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MPHLCAIF_00512	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MPHLCAIF_00513	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MPHLCAIF_00514	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MPHLCAIF_00515	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MPHLCAIF_00516	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MPHLCAIF_00517	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MPHLCAIF_00518	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MPHLCAIF_00519	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MPHLCAIF_00520	5.36e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MPHLCAIF_00521	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MPHLCAIF_00522	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MPHLCAIF_00523	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MPHLCAIF_00524	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MPHLCAIF_00525	2.92e-113	ywmA	-	-	-	-	-	-	-
MPHLCAIF_00526	4.54e-45	ywzB	-	-	S	-	-	-	membrane
MPHLCAIF_00527	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
MPHLCAIF_00528	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MPHLCAIF_00529	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MPHLCAIF_00530	5.21e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MPHLCAIF_00531	3.4e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MPHLCAIF_00533	9.06e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MPHLCAIF_00534	3.1e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MPHLCAIF_00535	2.18e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_00536	3.22e-109	ywmF	-	-	S	-	-	-	Peptidase M50
MPHLCAIF_00537	2.15e-19	csbD	-	-	K	-	-	-	CsbD-like
MPHLCAIF_00538	6.75e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MPHLCAIF_00539	6.46e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MPHLCAIF_00540	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MPHLCAIF_00541	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00542	1.69e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MPHLCAIF_00543	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MPHLCAIF_00544	1.28e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
MPHLCAIF_00545	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MPHLCAIF_00546	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MPHLCAIF_00547	6.7e-234	-	-	-	M	-	-	-	NeuB family
MPHLCAIF_00548	5.63e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MPHLCAIF_00549	2.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MPHLCAIF_00550	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MPHLCAIF_00551	9.05e-93	ywnJ	-	-	S	-	-	-	VanZ like family
MPHLCAIF_00552	1.72e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MPHLCAIF_00553	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MPHLCAIF_00554	3.76e-287	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MPHLCAIF_00555	7.16e-101	-	-	-	-	-	-	-	-
MPHLCAIF_00556	3e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
MPHLCAIF_00557	1.54e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_00558	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MPHLCAIF_00559	1.14e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
MPHLCAIF_00560	3.21e-268	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00561	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
MPHLCAIF_00562	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MPHLCAIF_00563	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MPHLCAIF_00564	9.37e-168	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MPHLCAIF_00565	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MPHLCAIF_00566	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MPHLCAIF_00567	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MPHLCAIF_00568	7.66e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MPHLCAIF_00569	4.66e-186	ywpD	-	-	T	-	-	-	Histidine kinase
MPHLCAIF_00570	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MPHLCAIF_00571	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
MPHLCAIF_00572	2.79e-40	ywpG	-	-	-	-	-	-	-
MPHLCAIF_00573	4.23e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MPHLCAIF_00574	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MPHLCAIF_00575	3.57e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MPHLCAIF_00576	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MPHLCAIF_00577	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MPHLCAIF_00578	3.6e-25	-	-	-	-	-	-	-	-
MPHLCAIF_00579	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MPHLCAIF_00580	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MPHLCAIF_00581	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MPHLCAIF_00582	6.34e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MPHLCAIF_00583	1.3e-38	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MPHLCAIF_00584	1.45e-108	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MPHLCAIF_00586	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MPHLCAIF_00587	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
MPHLCAIF_00588	2.5e-26	-	-	-	-	-	-	-	-
MPHLCAIF_00589	1.3e-23	-	-	-	-	-	-	-	-
MPHLCAIF_00590	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MPHLCAIF_00591	9.77e-48	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
MPHLCAIF_00593	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MPHLCAIF_00594	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00595	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
MPHLCAIF_00597	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MPHLCAIF_00598	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MPHLCAIF_00599	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MPHLCAIF_00600	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MPHLCAIF_00601	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
MPHLCAIF_00602	5.08e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MPHLCAIF_00603	1.4e-17	-	-	-	-	-	-	-	-
MPHLCAIF_00604	8.48e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MPHLCAIF_00605	7.86e-162	cotB	-	-	-	ko:K06325	-	ko00000	-
MPHLCAIF_00606	4.33e-162	ywrJ	-	-	-	-	-	-	-
MPHLCAIF_00607	9.31e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MPHLCAIF_00608	1.37e-217	alsR	-	-	K	-	-	-	LysR substrate binding domain
MPHLCAIF_00609	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MPHLCAIF_00610	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MPHLCAIF_00611	1.24e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MPHLCAIF_00612	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
MPHLCAIF_00613	3.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MPHLCAIF_00614	3.68e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MPHLCAIF_00615	1.59e-201	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MPHLCAIF_00616	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MPHLCAIF_00617	3.12e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MPHLCAIF_00618	8.06e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MPHLCAIF_00619	5.85e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MPHLCAIF_00620	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MPHLCAIF_00621	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MPHLCAIF_00622	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MPHLCAIF_00623	2.29e-29	ywtC	-	-	-	-	-	-	-
MPHLCAIF_00624	9.23e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MPHLCAIF_00625	1.99e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MPHLCAIF_00626	3.53e-178	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00627	8.52e-260	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_00628	1.05e-255	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MPHLCAIF_00629	3.4e-238	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MPHLCAIF_00630	5.41e-311	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MPHLCAIF_00631	3.57e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MPHLCAIF_00632	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MPHLCAIF_00633	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MPHLCAIF_00634	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MPHLCAIF_00635	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MPHLCAIF_00636	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MPHLCAIF_00637	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MPHLCAIF_00639	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MPHLCAIF_00640	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MPHLCAIF_00641	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
MPHLCAIF_00642	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MPHLCAIF_00643	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MPHLCAIF_00646	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_00647	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MPHLCAIF_00648	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MPHLCAIF_00649	5.99e-286	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MPHLCAIF_00650	8.93e-124	-	-	-	S	-	-	-	YcxB-like protein
MPHLCAIF_00651	3.27e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_00652	2.81e-316	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
MPHLCAIF_00653	8.24e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MPHLCAIF_00654	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MPHLCAIF_00655	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MPHLCAIF_00656	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MPHLCAIF_00657	4.3e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MPHLCAIF_00658	1.25e-207	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MPHLCAIF_00659	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MPHLCAIF_00660	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MPHLCAIF_00661	4.02e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MPHLCAIF_00662	6.45e-55	yclD	-	-	-	-	-	-	-
MPHLCAIF_00663	1.84e-200	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MPHLCAIF_00664	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MPHLCAIF_00665	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MPHLCAIF_00667	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MPHLCAIF_00668	8.22e-288	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MPHLCAIF_00669	5.28e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MPHLCAIF_00670	1.38e-154	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MPHLCAIF_00671	5.33e-278	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MPHLCAIF_00672	5.43e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_00673	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MPHLCAIF_00674	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MPHLCAIF_00676	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MPHLCAIF_00677	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MPHLCAIF_00679	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00680	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00681	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_00682	4.69e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MPHLCAIF_00683	1.18e-96	-	-	-	V	-	-	-	Restriction endonuclease
MPHLCAIF_00684	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MPHLCAIF_00685	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00686	8.65e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MPHLCAIF_00687	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
MPHLCAIF_00688	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MPHLCAIF_00689	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_00690	3.26e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MPHLCAIF_00691	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MPHLCAIF_00692	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MPHLCAIF_00693	1.39e-185	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_00694	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00695	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MPHLCAIF_00696	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MPHLCAIF_00697	1.34e-74	-	-	-	-	-	-	-	-
MPHLCAIF_00698	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MPHLCAIF_00699	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MPHLCAIF_00700	3.1e-268	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MPHLCAIF_00701	3.39e-255	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MPHLCAIF_00703	1.25e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MPHLCAIF_00704	1.32e-24	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
MPHLCAIF_00705	2.68e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MPHLCAIF_00707	3.15e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MPHLCAIF_00708	4.46e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MPHLCAIF_00709	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MPHLCAIF_00710	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MPHLCAIF_00711	2.8e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MPHLCAIF_00712	3.31e-237	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MPHLCAIF_00713	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00714	1.2e-153	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MPHLCAIF_00716	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
MPHLCAIF_00717	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MPHLCAIF_00718	3.5e-219	ycsN	-	-	S	-	-	-	Oxidoreductase
MPHLCAIF_00719	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MPHLCAIF_00720	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MPHLCAIF_00721	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
MPHLCAIF_00722	1.07e-206	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_00723	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MPHLCAIF_00724	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MPHLCAIF_00725	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
MPHLCAIF_00726	2.65e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MPHLCAIF_00727	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MPHLCAIF_00728	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MPHLCAIF_00729	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MPHLCAIF_00730	8.17e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MPHLCAIF_00731	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MPHLCAIF_00733	1.84e-34	-	-	-	-	-	-	-	-
MPHLCAIF_00734	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
MPHLCAIF_00736	6.14e-53	-	-	-	-	-	-	-	-
MPHLCAIF_00737	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MPHLCAIF_00738	1.67e-42	ydaS	-	-	S	-	-	-	membrane
MPHLCAIF_00739	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MPHLCAIF_00740	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
MPHLCAIF_00741	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MPHLCAIF_00742	2.17e-78	ydbB	-	-	G	-	-	-	Cupin domain
MPHLCAIF_00743	3.66e-82	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MPHLCAIF_00744	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MPHLCAIF_00745	6.07e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MPHLCAIF_00746	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MPHLCAIF_00747	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MPHLCAIF_00748	8.93e-290	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MPHLCAIF_00749	5.38e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
MPHLCAIF_00750	5.36e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_00751	4.95e-158	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MPHLCAIF_00752	9.32e-70	ydbL	-	-	-	-	-	-	-
MPHLCAIF_00753	6.12e-279	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MPHLCAIF_00754	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
MPHLCAIF_00755	2.1e-11	-	-	-	S	-	-	-	Fur-regulated basic protein A
MPHLCAIF_00756	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MPHLCAIF_00757	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
MPHLCAIF_00758	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MPHLCAIF_00759	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MPHLCAIF_00760	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MPHLCAIF_00761	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MPHLCAIF_00762	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MPHLCAIF_00763	2.08e-138	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MPHLCAIF_00764	1.87e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MPHLCAIF_00765	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MPHLCAIF_00766	2.07e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MPHLCAIF_00767	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MPHLCAIF_00768	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MPHLCAIF_00769	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MPHLCAIF_00770	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MPHLCAIF_00771	1e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MPHLCAIF_00772	1.08e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MPHLCAIF_00773	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MPHLCAIF_00774	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MPHLCAIF_00775	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_00776	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MPHLCAIF_00779	4.42e-105	ydcG	-	-	S	-	-	-	EVE domain
MPHLCAIF_00780	1.79e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_00781	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MPHLCAIF_00782	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MPHLCAIF_00790	5.14e-269	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MPHLCAIF_00791	1.65e-118	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MPHLCAIF_00792	1.91e-81	-	-	-	K	-	-	-	Transcriptional
MPHLCAIF_00793	8.96e-24	-	-	-	-	-	-	-	-
MPHLCAIF_00794	1.35e-55	-	-	-	-	-	-	-	-
MPHLCAIF_00796	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MPHLCAIF_00797	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
MPHLCAIF_00798	2.58e-254	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
MPHLCAIF_00799	2.68e-23	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MPHLCAIF_00802	2.49e-63	yddA	-	-	-	-	-	-	-
MPHLCAIF_00803	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MPHLCAIF_00804	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
MPHLCAIF_00805	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MPHLCAIF_00806	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MPHLCAIF_00807	1.89e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MPHLCAIF_00808	1.08e-237	ygaE	-	-	S	-	-	-	Membrane
MPHLCAIF_00809	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MPHLCAIF_00810	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MPHLCAIF_00811	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MPHLCAIF_00812	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MPHLCAIF_00813	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_00814	1.73e-48	yfhS	-	-	-	-	-	-	-
MPHLCAIF_00815	1.99e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MPHLCAIF_00816	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MPHLCAIF_00817	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MPHLCAIF_00818	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MPHLCAIF_00819	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MPHLCAIF_00820	6.3e-66	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MPHLCAIF_00821	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MPHLCAIF_00822	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
MPHLCAIF_00823	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
MPHLCAIF_00824	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
MPHLCAIF_00826	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MPHLCAIF_00827	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MPHLCAIF_00828	1.88e-220	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MPHLCAIF_00830	3.61e-34	yfhD	-	-	S	-	-	-	YfhD-like protein
MPHLCAIF_00831	4.76e-137	yfhC	-	-	C	-	-	-	nitroreductase
MPHLCAIF_00832	3.1e-214	yfhB	-	-	S	-	-	-	PhzF family
MPHLCAIF_00833	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00834	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_00835	3.15e-230	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MPHLCAIF_00836	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MPHLCAIF_00837	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
MPHLCAIF_00838	7.36e-215	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MPHLCAIF_00839	1.74e-131	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MPHLCAIF_00840	4.67e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MPHLCAIF_00841	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_00842	1.57e-136	yfiR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00843	6.57e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MPHLCAIF_00844	5.67e-121	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MPHLCAIF_00845	1.38e-121	padR	-	-	K	-	-	-	transcriptional
MPHLCAIF_00846	6.08e-256	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MPHLCAIF_00847	1.15e-261	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_00848	1.78e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_00849	5.82e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MPHLCAIF_00850	1.7e-272	baeS	-	-	T	-	-	-	Histidine kinase
MPHLCAIF_00852	4.36e-249	-	-	-	S	-	-	-	Oxidoreductase
MPHLCAIF_00853	2.46e-32	-	-	-	S	-	-	-	Oxidoreductase
MPHLCAIF_00854	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
MPHLCAIF_00855	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_00856	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
MPHLCAIF_00857	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MPHLCAIF_00858	4.74e-83	yfiD3	-	-	S	-	-	-	DoxX
MPHLCAIF_00859	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_00860	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MPHLCAIF_00861	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MPHLCAIF_00862	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_00863	1.23e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MPHLCAIF_00864	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MPHLCAIF_00865	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
MPHLCAIF_00866	1.94e-270	yfjB	-	-	-	-	-	-	-
MPHLCAIF_00867	1.02e-184	yfjC	-	-	-	-	-	-	-
MPHLCAIF_00868	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
MPHLCAIF_00869	1e-105	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
MPHLCAIF_00870	2.9e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
MPHLCAIF_00871	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MPHLCAIF_00872	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MPHLCAIF_00873	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MPHLCAIF_00874	4.89e-264	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MPHLCAIF_00875	4.56e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MPHLCAIF_00876	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MPHLCAIF_00878	4.55e-109	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MPHLCAIF_00879	7.83e-240	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MPHLCAIF_00880	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
MPHLCAIF_00881	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MPHLCAIF_00882	5.57e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MPHLCAIF_00883	1.24e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MPHLCAIF_00884	7.99e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MPHLCAIF_00885	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MPHLCAIF_00886	3.26e-36	yfjT	-	-	-	-	-	-	-
MPHLCAIF_00887	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
MPHLCAIF_00888	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MPHLCAIF_00889	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
MPHLCAIF_00890	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MPHLCAIF_00891	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00892	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MPHLCAIF_00893	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
MPHLCAIF_00894	5.04e-109	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MPHLCAIF_00895	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MPHLCAIF_00896	5.94e-264	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_00897	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
MPHLCAIF_00898	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MPHLCAIF_00899	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MPHLCAIF_00900	1.34e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MPHLCAIF_00901	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MPHLCAIF_00902	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MPHLCAIF_00903	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MPHLCAIF_00904	3.92e-86	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MPHLCAIF_00905	6.07e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MPHLCAIF_00906	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MPHLCAIF_00907	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MPHLCAIF_00908	7.41e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MPHLCAIF_00909	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MPHLCAIF_00910	1.88e-222	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MPHLCAIF_00911	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MPHLCAIF_00912	1.44e-74	yisL	-	-	S	-	-	-	UPF0344 protein
MPHLCAIF_00913	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MPHLCAIF_00914	6.1e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MPHLCAIF_00915	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MPHLCAIF_00916	4.02e-151	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MPHLCAIF_00917	7.14e-311	yisQ	-	-	V	-	-	-	Mate efflux family protein
MPHLCAIF_00918	1.16e-206	yisR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_00919	5.88e-232	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MPHLCAIF_00920	2.11e-248	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MPHLCAIF_00921	1.41e-119	yisT	-	-	S	-	-	-	DinB family
MPHLCAIF_00922	1.28e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MPHLCAIF_00923	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_00924	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MPHLCAIF_00925	5.29e-198	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MPHLCAIF_00926	1.77e-96	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_00927	2.95e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_00928	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MPHLCAIF_00929	4.29e-77	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MPHLCAIF_00930	1.59e-203	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MPHLCAIF_00932	7.32e-49	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MPHLCAIF_00933	4.16e-198	yitS	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00934	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MPHLCAIF_00935	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MPHLCAIF_00936	7.41e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MPHLCAIF_00937	1.92e-08	-	-	-	-	-	-	-	-
MPHLCAIF_00938	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MPHLCAIF_00939	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MPHLCAIF_00940	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MPHLCAIF_00941	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
MPHLCAIF_00942	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MPHLCAIF_00943	5.71e-69	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MPHLCAIF_00944	1.68e-37	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MPHLCAIF_00945	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MPHLCAIF_00946	1.37e-290	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MPHLCAIF_00947	1.81e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MPHLCAIF_00948	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MPHLCAIF_00949	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MPHLCAIF_00950	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MPHLCAIF_00951	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MPHLCAIF_00952	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MPHLCAIF_00953	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MPHLCAIF_00954	1.51e-306	ygxB	-	-	M	-	-	-	Conserved TM helix
MPHLCAIF_00955	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MPHLCAIF_00957	5.71e-48	yrhC	-	-	S	-	-	-	YrhC-like protein
MPHLCAIF_00958	2.86e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MPHLCAIF_00959	3.91e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MPHLCAIF_00960	1.14e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MPHLCAIF_00961	2.83e-152	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MPHLCAIF_00962	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MPHLCAIF_00963	1.65e-101	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MPHLCAIF_00964	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MPHLCAIF_00965	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MPHLCAIF_00966	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MPHLCAIF_00967	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MPHLCAIF_00968	2.57e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MPHLCAIF_00969	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MPHLCAIF_00970	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MPHLCAIF_00971	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MPHLCAIF_00972	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MPHLCAIF_00973	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MPHLCAIF_00974	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MPHLCAIF_00975	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
MPHLCAIF_00976	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MPHLCAIF_00977	3.93e-182	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MPHLCAIF_00978	1.54e-137	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_00979	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_00980	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MPHLCAIF_00981	8.4e-42	yrzR	-	-	-	-	-	-	-
MPHLCAIF_00982	1.38e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_00983	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MPHLCAIF_00984	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MPHLCAIF_00985	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MPHLCAIF_00986	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MPHLCAIF_00987	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_00988	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MPHLCAIF_00989	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MPHLCAIF_00990	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MPHLCAIF_00991	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MPHLCAIF_00993	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MPHLCAIF_00994	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MPHLCAIF_00995	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MPHLCAIF_00996	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MPHLCAIF_00997	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MPHLCAIF_00998	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MPHLCAIF_00999	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MPHLCAIF_01000	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MPHLCAIF_01001	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MPHLCAIF_01002	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_01003	8.64e-145	yrbG	-	-	S	-	-	-	membrane
MPHLCAIF_01004	6.2e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MPHLCAIF_01005	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MPHLCAIF_01006	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MPHLCAIF_01007	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MPHLCAIF_01008	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MPHLCAIF_01009	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MPHLCAIF_01010	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MPHLCAIF_01011	1.85e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MPHLCAIF_01012	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
MPHLCAIF_01013	7.93e-248	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MPHLCAIF_01014	5.47e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
MPHLCAIF_01016	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
MPHLCAIF_01017	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MPHLCAIF_01018	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MPHLCAIF_01019	5.13e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MPHLCAIF_01020	3.45e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MPHLCAIF_01021	4.41e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MPHLCAIF_01022	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MPHLCAIF_01023	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MPHLCAIF_01024	1.17e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MPHLCAIF_01025	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MPHLCAIF_01026	2.54e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MPHLCAIF_01027	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MPHLCAIF_01028	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MPHLCAIF_01029	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MPHLCAIF_01030	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MPHLCAIF_01031	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MPHLCAIF_01032	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MPHLCAIF_01033	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MPHLCAIF_01034	7.44e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MPHLCAIF_01035	4.13e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MPHLCAIF_01036	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MPHLCAIF_01037	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MPHLCAIF_01038	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MPHLCAIF_01039	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MPHLCAIF_01040	2.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MPHLCAIF_01041	2.02e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MPHLCAIF_01042	2.47e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MPHLCAIF_01043	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MPHLCAIF_01044	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MPHLCAIF_01045	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MPHLCAIF_01046	1.53e-35	-	-	-	-	-	-	-	-
MPHLCAIF_01047	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MPHLCAIF_01048	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MPHLCAIF_01049	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MPHLCAIF_01050	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MPHLCAIF_01051	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MPHLCAIF_01052	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MPHLCAIF_01053	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MPHLCAIF_01054	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MPHLCAIF_01055	4.77e-116	ysxD	-	-	-	-	-	-	-
MPHLCAIF_01056	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MPHLCAIF_01057	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MPHLCAIF_01058	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MPHLCAIF_01059	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MPHLCAIF_01060	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MPHLCAIF_01061	4.53e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MPHLCAIF_01062	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MPHLCAIF_01063	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MPHLCAIF_01064	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MPHLCAIF_01065	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MPHLCAIF_01066	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MPHLCAIF_01067	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MPHLCAIF_01068	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MPHLCAIF_01070	1.38e-84	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MPHLCAIF_01071	4.77e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01072	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MPHLCAIF_01073	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_01074	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MPHLCAIF_01075	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_01076	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MPHLCAIF_01077	1.5e-60	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_01078	1.22e-81	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_01079	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MPHLCAIF_01080	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MPHLCAIF_01081	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_01082	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MPHLCAIF_01083	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MPHLCAIF_01084	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MPHLCAIF_01085	1.05e-26	yxzF	-	-	-	-	-	-	-
MPHLCAIF_01086	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MPHLCAIF_01087	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MPHLCAIF_01088	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MPHLCAIF_01089	1.55e-176	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MPHLCAIF_01090	2.01e-211	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_01091	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MPHLCAIF_01092	1.63e-39	-	-	-	-	-	-	-	-
MPHLCAIF_01093	1.93e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
MPHLCAIF_01094	2.6e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_01095	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MPHLCAIF_01096	6.19e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MPHLCAIF_01097	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MPHLCAIF_01098	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MPHLCAIF_01099	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MPHLCAIF_01100	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MPHLCAIF_01101	1.09e-307	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MPHLCAIF_01102	0.0	-	-	-	O	-	-	-	Peptidase family M48
MPHLCAIF_01104	1.77e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MPHLCAIF_01105	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_01106	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MPHLCAIF_01107	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MPHLCAIF_01108	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MPHLCAIF_01109	1.74e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MPHLCAIF_01110	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
MPHLCAIF_01111	6.98e-243	-	-	-	T	-	-	-	Signal transduction histidine kinase
MPHLCAIF_01112	6.34e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
MPHLCAIF_01113	5.24e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MPHLCAIF_01116	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
MPHLCAIF_01117	1.5e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MPHLCAIF_01118	3.66e-274	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MPHLCAIF_01119	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MPHLCAIF_01120	3.99e-149	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MPHLCAIF_01121	6.6e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MPHLCAIF_01122	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MPHLCAIF_01123	2.42e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MPHLCAIF_01124	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MPHLCAIF_01125	9.87e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MPHLCAIF_01126	2.28e-63	yxiS	-	-	-	-	-	-	-
MPHLCAIF_01127	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MPHLCAIF_01128	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MPHLCAIF_01129	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
MPHLCAIF_01130	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MPHLCAIF_01131	1.07e-142	-	-	-	-	-	-	-	-
MPHLCAIF_01132	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MPHLCAIF_01133	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MPHLCAIF_01134	3.52e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MPHLCAIF_01137	4.06e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MPHLCAIF_01140	1.86e-40	-	-	-	-	-	-	-	-
MPHLCAIF_01141	1.01e-120	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
MPHLCAIF_01142	8.22e-181	-	-	-	-	-	-	-	-
MPHLCAIF_01145	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
MPHLCAIF_01146	9.7e-68	yxxG	-	-	-	-	-	-	-
MPHLCAIF_01147	4.67e-89	yxiG	-	-	-	-	-	-	-
MPHLCAIF_01148	4.48e-58	-	-	-	-	-	-	-	-
MPHLCAIF_01149	7.13e-100	-	-	-	-	-	-	-	-
MPHLCAIF_01150	5.36e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
MPHLCAIF_01151	6.44e-178	-	-	-	-	-	-	-	-
MPHLCAIF_01153	1.27e-69	-	-	-	-	-	-	-	-
MPHLCAIF_01154	2.23e-99	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MPHLCAIF_01155	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MPHLCAIF_01156	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MPHLCAIF_01157	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_01158	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_01159	4.54e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
MPHLCAIF_01160	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MPHLCAIF_01161	2.02e-217	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MPHLCAIF_01162	2.15e-115	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MPHLCAIF_01163	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_01164	3.36e-68	-	-	-	-	-	-	-	-
MPHLCAIF_01165	1.83e-221	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MPHLCAIF_01167	7.83e-269	-	-	-	S	-	-	-	nuclease activity
MPHLCAIF_01168	3.27e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
MPHLCAIF_01169	1.78e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MPHLCAIF_01170	0.0	-	-	-	L	-	-	-	HKD family nuclease
MPHLCAIF_01171	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MPHLCAIF_01172	2.01e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
MPHLCAIF_01173	7.08e-307	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MPHLCAIF_01174	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MPHLCAIF_01175	2.24e-204	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MPHLCAIF_01176	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MPHLCAIF_01177	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MPHLCAIF_01178	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MPHLCAIF_01179	7.06e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MPHLCAIF_01180	8.39e-194	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
MPHLCAIF_01181	1.49e-253	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
MPHLCAIF_01182	1.87e-316	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MPHLCAIF_01183	2.89e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MPHLCAIF_01184	1.13e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_01185	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MPHLCAIF_01186	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MPHLCAIF_01187	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_01188	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPHLCAIF_01189	3.87e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MPHLCAIF_01190	5.69e-194	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MPHLCAIF_01193	7.32e-42	yxeE	-	-	-	-	-	-	-
MPHLCAIF_01194	2.66e-28	yxeD	-	-	-	-	-	-	-
MPHLCAIF_01195	1.13e-89	-	-	-	-	-	-	-	-
MPHLCAIF_01196	7.4e-227	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_01197	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MPHLCAIF_01198	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MPHLCAIF_01199	9.7e-88	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_01200	6.59e-67	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_01201	9.03e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_01202	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_01203	6.95e-205	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MPHLCAIF_01204	2.29e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MPHLCAIF_01205	4.4e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MPHLCAIF_01206	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MPHLCAIF_01207	1.34e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MPHLCAIF_01208	8.63e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MPHLCAIF_01209	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MPHLCAIF_01210	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MPHLCAIF_01211	2.43e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MPHLCAIF_01212	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MPHLCAIF_01216	1.24e-22	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	transcriptional
MPHLCAIF_01217	2.01e-156	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MPHLCAIF_01218	9.3e-23	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MPHLCAIF_01220	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MPHLCAIF_01221	2.4e-233	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_01222	2.22e-38	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_01223	4.47e-103	-	-	-	T	-	-	-	HPP family
MPHLCAIF_01224	2.23e-17	-	-	-	S	-	-	-	CGNR zinc finger
MPHLCAIF_01226	7.27e-55	-	-	-	-	-	-	-	-
MPHLCAIF_01227	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MPHLCAIF_01228	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MPHLCAIF_01229	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_01230	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MPHLCAIF_01231	1.08e-139	tmrB	-	-	S	-	-	-	AAA domain
MPHLCAIF_01232	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MPHLCAIF_01233	2.99e-117	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MPHLCAIF_01234	8.63e-97	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_01235	2.07e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MPHLCAIF_01236	1.33e-268	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MPHLCAIF_01237	2.38e-82	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MPHLCAIF_01238	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MPHLCAIF_01239	7.37e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MPHLCAIF_01240	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
MPHLCAIF_01241	7.79e-105	ycgB	-	-	-	-	-	-	-
MPHLCAIF_01242	0.0	ycgA	-	-	S	-	-	-	Membrane
MPHLCAIF_01243	4.44e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MPHLCAIF_01244	4.73e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MPHLCAIF_01245	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MPHLCAIF_01246	5.2e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MPHLCAIF_01247	1.38e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MPHLCAIF_01248	1.19e-260	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MPHLCAIF_01249	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MPHLCAIF_01251	1.81e-108	-	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_01252	5.09e-304	pre	-	-	D	-	-	-	plasmid recombination enzyme
MPHLCAIF_01253	9.66e-92	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
MPHLCAIF_01255	2.17e-224	-	-	-	L	-	-	-	Replication protein
MPHLCAIF_01256	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MPHLCAIF_01257	1.71e-132	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MPHLCAIF_01258	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
MPHLCAIF_01259	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MPHLCAIF_01260	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_01261	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MPHLCAIF_01262	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MPHLCAIF_01263	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MPHLCAIF_01264	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MPHLCAIF_01265	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MPHLCAIF_01266	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPHLCAIF_01267	1.1e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPHLCAIF_01268	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MPHLCAIF_01269	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MPHLCAIF_01270	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPHLCAIF_01271	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MPHLCAIF_01272	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MPHLCAIF_01273	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MPHLCAIF_01274	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MPHLCAIF_01275	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MPHLCAIF_01276	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MPHLCAIF_01277	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MPHLCAIF_01278	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MPHLCAIF_01279	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MPHLCAIF_01280	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MPHLCAIF_01281	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MPHLCAIF_01282	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MPHLCAIF_01283	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MPHLCAIF_01284	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MPHLCAIF_01285	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MPHLCAIF_01286	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MPHLCAIF_01287	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MPHLCAIF_01288	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MPHLCAIF_01289	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MPHLCAIF_01290	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MPHLCAIF_01291	6.89e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MPHLCAIF_01292	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MPHLCAIF_01293	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MPHLCAIF_01294	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MPHLCAIF_01295	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MPHLCAIF_01296	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MPHLCAIF_01297	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MPHLCAIF_01298	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MPHLCAIF_01299	7.13e-228	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MPHLCAIF_01300	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MPHLCAIF_01301	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MPHLCAIF_01302	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MPHLCAIF_01303	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MPHLCAIF_01304	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MPHLCAIF_01305	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPHLCAIF_01306	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MPHLCAIF_01307	2.43e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MPHLCAIF_01308	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MPHLCAIF_01309	1.64e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MPHLCAIF_01310	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MPHLCAIF_01311	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MPHLCAIF_01312	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MPHLCAIF_01313	1.08e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MPHLCAIF_01314	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MPHLCAIF_01315	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MPHLCAIF_01316	8.65e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MPHLCAIF_01317	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MPHLCAIF_01318	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MPHLCAIF_01319	5.46e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MPHLCAIF_01320	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MPHLCAIF_01321	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MPHLCAIF_01322	2.13e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MPHLCAIF_01323	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MPHLCAIF_01324	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MPHLCAIF_01325	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MPHLCAIF_01326	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MPHLCAIF_01327	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MPHLCAIF_01328	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MPHLCAIF_01329	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MPHLCAIF_01330	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MPHLCAIF_01335	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MPHLCAIF_01336	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MPHLCAIF_01337	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MPHLCAIF_01338	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MPHLCAIF_01339	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MPHLCAIF_01340	1.62e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MPHLCAIF_01341	1.96e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MPHLCAIF_01342	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MPHLCAIF_01343	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MPHLCAIF_01344	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MPHLCAIF_01345	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
MPHLCAIF_01346	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MPHLCAIF_01347	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MPHLCAIF_01348	1.36e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MPHLCAIF_01349	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MPHLCAIF_01350	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MPHLCAIF_01351	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MPHLCAIF_01352	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MPHLCAIF_01353	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
MPHLCAIF_01354	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
MPHLCAIF_01355	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_01356	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_01357	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MPHLCAIF_01358	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
MPHLCAIF_01359	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MPHLCAIF_01360	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MPHLCAIF_01361	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MPHLCAIF_01362	2.83e-282	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MPHLCAIF_01363	2.36e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MPHLCAIF_01364	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MPHLCAIF_01365	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MPHLCAIF_01366	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MPHLCAIF_01367	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MPHLCAIF_01368	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MPHLCAIF_01369	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MPHLCAIF_01370	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MPHLCAIF_01371	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MPHLCAIF_01372	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MPHLCAIF_01373	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MPHLCAIF_01374	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MPHLCAIF_01375	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MPHLCAIF_01376	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MPHLCAIF_01377	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MPHLCAIF_01378	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MPHLCAIF_01379	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MPHLCAIF_01380	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MPHLCAIF_01381	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MPHLCAIF_01382	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MPHLCAIF_01383	1.14e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MPHLCAIF_01384	4.74e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MPHLCAIF_01385	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MPHLCAIF_01386	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MPHLCAIF_01387	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MPHLCAIF_01388	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MPHLCAIF_01389	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MPHLCAIF_01390	2.81e-100	ylxL	-	-	-	-	-	-	-
MPHLCAIF_01391	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_01392	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MPHLCAIF_01393	4.54e-60	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MPHLCAIF_01394	5.88e-54	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MPHLCAIF_01395	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MPHLCAIF_01396	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MPHLCAIF_01397	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MPHLCAIF_01398	1.28e-199	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MPHLCAIF_01399	1.89e-254	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MPHLCAIF_01400	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPHLCAIF_01401	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MPHLCAIF_01402	8.38e-148	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MPHLCAIF_01403	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MPHLCAIF_01404	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MPHLCAIF_01405	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MPHLCAIF_01406	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MPHLCAIF_01407	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MPHLCAIF_01408	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MPHLCAIF_01409	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MPHLCAIF_01410	3.12e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MPHLCAIF_01411	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MPHLCAIF_01412	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MPHLCAIF_01413	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MPHLCAIF_01414	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MPHLCAIF_01415	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MPHLCAIF_01416	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MPHLCAIF_01417	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MPHLCAIF_01418	7.5e-188	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MPHLCAIF_01419	1.07e-95	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MPHLCAIF_01420	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MPHLCAIF_01421	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MPHLCAIF_01422	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MPHLCAIF_01423	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MPHLCAIF_01424	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MPHLCAIF_01425	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MPHLCAIF_01426	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MPHLCAIF_01427	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MPHLCAIF_01428	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MPHLCAIF_01429	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MPHLCAIF_01430	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MPHLCAIF_01431	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MPHLCAIF_01432	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MPHLCAIF_01433	0.0	ylqG	-	-	-	-	-	-	-
MPHLCAIF_01434	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MPHLCAIF_01435	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MPHLCAIF_01436	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MPHLCAIF_01437	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MPHLCAIF_01438	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MPHLCAIF_01439	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
MPHLCAIF_01440	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MPHLCAIF_01441	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MPHLCAIF_01442	1.96e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MPHLCAIF_01443	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MPHLCAIF_01444	1.67e-114	-	-	-	-	-	-	-	-
MPHLCAIF_01445	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MPHLCAIF_01446	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MPHLCAIF_01447	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MPHLCAIF_01448	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MPHLCAIF_01449	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MPHLCAIF_01450	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MPHLCAIF_01451	1.68e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MPHLCAIF_01452	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MPHLCAIF_01453	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MPHLCAIF_01454	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MPHLCAIF_01455	5.89e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MPHLCAIF_01456	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MPHLCAIF_01457	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01458	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MPHLCAIF_01459	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MPHLCAIF_01460	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MPHLCAIF_01461	4.57e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MPHLCAIF_01462	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MPHLCAIF_01463	3.54e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MPHLCAIF_01464	2.16e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MPHLCAIF_01465	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MPHLCAIF_01466	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MPHLCAIF_01467	7.97e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MPHLCAIF_01468	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MPHLCAIF_01469	4.21e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MPHLCAIF_01470	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MPHLCAIF_01471	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MPHLCAIF_01472	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MPHLCAIF_01473	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
MPHLCAIF_01474	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MPHLCAIF_01475	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MPHLCAIF_01476	3.78e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MPHLCAIF_01477	8.38e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MPHLCAIF_01478	1.45e-185	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MPHLCAIF_01479	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MPHLCAIF_01480	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MPHLCAIF_01481	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MPHLCAIF_01482	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MPHLCAIF_01483	3e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MPHLCAIF_01484	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MPHLCAIF_01485	4.97e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MPHLCAIF_01486	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MPHLCAIF_01487	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MPHLCAIF_01488	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MPHLCAIF_01489	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MPHLCAIF_01490	5.99e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MPHLCAIF_01491	8.02e-291	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MPHLCAIF_01492	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MPHLCAIF_01493	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MPHLCAIF_01494	1.89e-98	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MPHLCAIF_01495	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MPHLCAIF_01496	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MPHLCAIF_01497	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MPHLCAIF_01498	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MPHLCAIF_01499	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MPHLCAIF_01500	1.28e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MPHLCAIF_01501	9.03e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MPHLCAIF_01502	9.17e-204	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MPHLCAIF_01503	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
MPHLCAIF_01504	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MPHLCAIF_01505	1.57e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MPHLCAIF_01506	6.57e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_01507	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_01508	3.49e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MPHLCAIF_01510	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MPHLCAIF_01511	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MPHLCAIF_01512	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MPHLCAIF_01513	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
MPHLCAIF_01514	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01515	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01516	1.37e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MPHLCAIF_01517	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MPHLCAIF_01518	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MPHLCAIF_01519	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MPHLCAIF_01520	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MPHLCAIF_01521	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MPHLCAIF_01522	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MPHLCAIF_01523	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MPHLCAIF_01524	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MPHLCAIF_01525	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
MPHLCAIF_01526	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MPHLCAIF_01527	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MPHLCAIF_01528	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MPHLCAIF_01529	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MPHLCAIF_01530	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
MPHLCAIF_01531	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MPHLCAIF_01532	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MPHLCAIF_01533	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MPHLCAIF_01535	1.67e-291	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MPHLCAIF_01536	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MPHLCAIF_01537	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MPHLCAIF_01538	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MPHLCAIF_01539	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MPHLCAIF_01540	1.43e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MPHLCAIF_01541	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
MPHLCAIF_01542	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MPHLCAIF_01543	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MPHLCAIF_01544	3.24e-89	ylbD	-	-	S	-	-	-	Putative coat protein
MPHLCAIF_01545	2.18e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MPHLCAIF_01546	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MPHLCAIF_01547	1.88e-80	ylbA	-	-	S	-	-	-	YugN-like family
MPHLCAIF_01548	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MPHLCAIF_01549	1.75e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MPHLCAIF_01550	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MPHLCAIF_01551	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MPHLCAIF_01552	2.28e-250	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MPHLCAIF_01553	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MPHLCAIF_01554	2.44e-213	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MPHLCAIF_01555	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MPHLCAIF_01556	2.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MPHLCAIF_01557	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MPHLCAIF_01558	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MPHLCAIF_01559	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MPHLCAIF_01560	1.41e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MPHLCAIF_01561	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MPHLCAIF_01562	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01563	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
MPHLCAIF_01564	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MPHLCAIF_01565	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MPHLCAIF_01566	1.74e-57	ylaE	-	-	-	-	-	-	-
MPHLCAIF_01568	1.79e-56	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_01569	1.44e-56	ylaB	-	-	-	-	-	-	-
MPHLCAIF_01570	0.0	ylaA	-	-	-	-	-	-	-
MPHLCAIF_01571	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MPHLCAIF_01572	2.57e-219	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MPHLCAIF_01573	3.84e-87	res	-	-	L	-	-	-	Resolvase, N terminal domain
MPHLCAIF_01574	6.97e-98	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MPHLCAIF_01575	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MPHLCAIF_01576	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MPHLCAIF_01579	3.17e-170	-	-	-	L	-	-	-	Phage integrase family
MPHLCAIF_01581	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MPHLCAIF_01582	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MPHLCAIF_01583	4.12e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MPHLCAIF_01584	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MPHLCAIF_01585	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MPHLCAIF_01586	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_01587	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_01588	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MPHLCAIF_01589	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MPHLCAIF_01590	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MPHLCAIF_01591	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MPHLCAIF_01592	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MPHLCAIF_01593	1.13e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MPHLCAIF_01594	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MPHLCAIF_01595	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MPHLCAIF_01596	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MPHLCAIF_01598	5e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MPHLCAIF_01599	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MPHLCAIF_01600	5.17e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MPHLCAIF_01601	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_01602	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MPHLCAIF_01603	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MPHLCAIF_01604	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MPHLCAIF_01605	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MPHLCAIF_01606	3.12e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MPHLCAIF_01607	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MPHLCAIF_01608	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MPHLCAIF_01609	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MPHLCAIF_01610	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MPHLCAIF_01611	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MPHLCAIF_01612	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MPHLCAIF_01613	1.11e-263	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MPHLCAIF_01614	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MPHLCAIF_01615	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MPHLCAIF_01616	8.17e-52	ysfE	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
MPHLCAIF_01618	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MPHLCAIF_01619	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MPHLCAIF_01620	2.47e-189	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MPHLCAIF_01621	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MPHLCAIF_01622	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MPHLCAIF_01623	1.24e-280	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MPHLCAIF_01624	5.81e-185	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MPHLCAIF_01625	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MPHLCAIF_01626	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MPHLCAIF_01627	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MPHLCAIF_01628	5.69e-126	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MPHLCAIF_01629	4.74e-72	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MPHLCAIF_01630	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MPHLCAIF_01631	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MPHLCAIF_01632	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
MPHLCAIF_01633	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MPHLCAIF_01634	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MPHLCAIF_01635	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MPHLCAIF_01637	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MPHLCAIF_01638	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MPHLCAIF_01639	4.62e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MPHLCAIF_01640	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_01641	1.15e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MPHLCAIF_01642	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MPHLCAIF_01644	5.5e-202	ytxC	-	-	S	-	-	-	YtxC-like family
MPHLCAIF_01645	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MPHLCAIF_01646	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MPHLCAIF_01647	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MPHLCAIF_01648	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MPHLCAIF_01649	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MPHLCAIF_01650	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MPHLCAIF_01651	1.64e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_01652	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MPHLCAIF_01653	4.54e-205	ytbE	-	-	S	-	-	-	reductase
MPHLCAIF_01654	1.63e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MPHLCAIF_01655	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MPHLCAIF_01656	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MPHLCAIF_01657	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MPHLCAIF_01658	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MPHLCAIF_01659	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_01660	4.23e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MPHLCAIF_01661	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MPHLCAIF_01662	3.34e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MPHLCAIF_01663	4.46e-93	ytwI	-	-	S	-	-	-	membrane
MPHLCAIF_01664	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MPHLCAIF_01665	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MPHLCAIF_01666	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MPHLCAIF_01667	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MPHLCAIF_01668	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MPHLCAIF_01669	5.1e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MPHLCAIF_01670	1.21e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MPHLCAIF_01671	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MPHLCAIF_01672	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MPHLCAIF_01673	5.12e-112	ytrI	-	-	-	-	-	-	-
MPHLCAIF_01674	1.15e-39	-	-	-	-	-	-	-	-
MPHLCAIF_01675	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MPHLCAIF_01676	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
MPHLCAIF_01677	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MPHLCAIF_01678	3.61e-144	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MPHLCAIF_01679	6.06e-136	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MPHLCAIF_01680	2.4e-60	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MPHLCAIF_01681	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MPHLCAIF_01682	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPHLCAIF_01683	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MPHLCAIF_01684	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
MPHLCAIF_01685	4.86e-41	yodI	-	-	-	-	-	-	-
MPHLCAIF_01686	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MPHLCAIF_01687	6.86e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MPHLCAIF_01688	2.08e-12	-	-	-	-	-	-	-	-
MPHLCAIF_01689	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
MPHLCAIF_01690	4.02e-138	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MPHLCAIF_01691	2.11e-33	yozD	-	-	S	-	-	-	YozD-like protein
MPHLCAIF_01693	7.44e-159	yodN	-	-	-	-	-	-	-
MPHLCAIF_01694	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MPHLCAIF_01695	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MPHLCAIF_01696	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MPHLCAIF_01697	3.56e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MPHLCAIF_01698	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MPHLCAIF_01699	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MPHLCAIF_01701	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MPHLCAIF_01703	1.97e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MPHLCAIF_01704	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MPHLCAIF_01705	1.06e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
MPHLCAIF_01706	2.74e-60	cgeA	-	-	-	ko:K06319	-	ko00000	-
MPHLCAIF_01707	9.37e-228	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MPHLCAIF_01708	1.34e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MPHLCAIF_01709	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MPHLCAIF_01710	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MPHLCAIF_01711	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MPHLCAIF_01712	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
MPHLCAIF_01713	7.03e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
MPHLCAIF_01714	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
MPHLCAIF_01715	5.59e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01716	1.28e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MPHLCAIF_01717	6.15e-136	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MPHLCAIF_01718	2.12e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MPHLCAIF_01719	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MPHLCAIF_01720	1.29e-232	yplP	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_01721	6.6e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MPHLCAIF_01722	4.7e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MPHLCAIF_01723	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MPHLCAIF_01724	1.8e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MPHLCAIF_01725	2.01e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
MPHLCAIF_01726	8.04e-183	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MPHLCAIF_01727	2.78e-98	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MPHLCAIF_01728	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MPHLCAIF_01729	2.32e-203	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MPHLCAIF_01730	2.42e-140	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MPHLCAIF_01731	5.2e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MPHLCAIF_01732	1.01e-223	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MPHLCAIF_01733	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MPHLCAIF_01734	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MPHLCAIF_01735	1.17e-22	degR	-	-	-	-	-	-	-
MPHLCAIF_01736	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MPHLCAIF_01737	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
MPHLCAIF_01738	1.56e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MPHLCAIF_01739	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MPHLCAIF_01740	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MPHLCAIF_01741	2.59e-05	-	-	-	-	ko:K06429	-	ko00000	-
MPHLCAIF_01742	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
MPHLCAIF_01743	1.08e-11	-	-	-	-	-	-	-	-
MPHLCAIF_01744	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MPHLCAIF_01745	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MPHLCAIF_01746	9.54e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MPHLCAIF_01747	3.58e-263	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MPHLCAIF_01748	1.43e-290	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MPHLCAIF_01749	9.13e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MPHLCAIF_01750	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MPHLCAIF_01751	2.36e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MPHLCAIF_01752	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MPHLCAIF_01753	4.02e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MPHLCAIF_01754	1.57e-237	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MPHLCAIF_01755	2.96e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MPHLCAIF_01756	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_01757	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MPHLCAIF_01759	2.84e-286	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MPHLCAIF_01760	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MPHLCAIF_01761	3.99e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MPHLCAIF_01762	1.98e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MPHLCAIF_01763	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MPHLCAIF_01764	2.59e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MPHLCAIF_01765	2.41e-92	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MPHLCAIF_01766	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
MPHLCAIF_01767	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
MPHLCAIF_01768	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MPHLCAIF_01771	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MPHLCAIF_01772	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MPHLCAIF_01773	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MPHLCAIF_01774	1.43e-121	ypoC	-	-	-	-	-	-	-
MPHLCAIF_01775	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MPHLCAIF_01776	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MPHLCAIF_01777	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MPHLCAIF_01778	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MPHLCAIF_01779	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01780	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MPHLCAIF_01781	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MPHLCAIF_01782	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MPHLCAIF_01783	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MPHLCAIF_01784	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MPHLCAIF_01785	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MPHLCAIF_01786	1.83e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MPHLCAIF_01787	2.45e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MPHLCAIF_01788	2.21e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MPHLCAIF_01789	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MPHLCAIF_01790	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MPHLCAIF_01791	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MPHLCAIF_01792	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MPHLCAIF_01793	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
MPHLCAIF_01794	1.15e-125	ypjA	-	-	S	-	-	-	membrane
MPHLCAIF_01795	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MPHLCAIF_01796	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MPHLCAIF_01797	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MPHLCAIF_01798	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MPHLCAIF_01799	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MPHLCAIF_01800	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MPHLCAIF_01801	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MPHLCAIF_01802	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MPHLCAIF_01803	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MPHLCAIF_01804	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MPHLCAIF_01805	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MPHLCAIF_01806	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MPHLCAIF_01807	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MPHLCAIF_01808	5e-229	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MPHLCAIF_01809	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MPHLCAIF_01810	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MPHLCAIF_01811	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MPHLCAIF_01812	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MPHLCAIF_01813	1.5e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MPHLCAIF_01814	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MPHLCAIF_01815	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MPHLCAIF_01816	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MPHLCAIF_01817	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MPHLCAIF_01818	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MPHLCAIF_01819	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MPHLCAIF_01820	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MPHLCAIF_01821	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MPHLCAIF_01822	8.71e-176	yphF	-	-	-	-	-	-	-
MPHLCAIF_01823	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MPHLCAIF_01824	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MPHLCAIF_01825	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MPHLCAIF_01826	2.06e-38	ypzH	-	-	-	-	-	-	-
MPHLCAIF_01827	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
MPHLCAIF_01828	1.11e-133	yphA	-	-	-	-	-	-	-
MPHLCAIF_01829	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
MPHLCAIF_01830	2.21e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MPHLCAIF_01831	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MPHLCAIF_01832	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MPHLCAIF_01833	4.83e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MPHLCAIF_01834	2.57e-141	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MPHLCAIF_01835	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MPHLCAIF_01836	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MPHLCAIF_01837	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MPHLCAIF_01838	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MPHLCAIF_01839	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MPHLCAIF_01840	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MPHLCAIF_01841	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MPHLCAIF_01842	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MPHLCAIF_01843	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
MPHLCAIF_01844	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MPHLCAIF_01845	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MPHLCAIF_01846	1.28e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MPHLCAIF_01847	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MPHLCAIF_01848	1.78e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MPHLCAIF_01849	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MPHLCAIF_01850	2.28e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MPHLCAIF_01851	8.13e-245	rsiX	-	-	-	-	-	-	-
MPHLCAIF_01852	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_01853	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_01854	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_01855	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MPHLCAIF_01856	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MPHLCAIF_01857	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MPHLCAIF_01858	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MPHLCAIF_01859	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MPHLCAIF_01860	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MPHLCAIF_01861	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MPHLCAIF_01862	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MPHLCAIF_01863	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MPHLCAIF_01864	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MPHLCAIF_01865	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MPHLCAIF_01866	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_01867	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MPHLCAIF_01868	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MPHLCAIF_01869	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MPHLCAIF_01870	5.92e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MPHLCAIF_01871	5.98e-72	ypuD	-	-	-	-	-	-	-
MPHLCAIF_01872	5.37e-122	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MPHLCAIF_01874	6.74e-30	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
MPHLCAIF_01876	5.68e-58	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MPHLCAIF_01878	3.82e-37	-	-	-	-	-	-	-	-
MPHLCAIF_01879	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
MPHLCAIF_01881	3.96e-84	-	-	-	O	-	-	-	Papain family cysteine protease
MPHLCAIF_01882	1.73e-13	-	-	-	-	-	-	-	-
MPHLCAIF_01883	6.4e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MPHLCAIF_01884	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MPHLCAIF_01885	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MPHLCAIF_01886	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MPHLCAIF_01887	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MPHLCAIF_01888	5.26e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPHLCAIF_01889	2.51e-32	yqzJ	-	-	-	-	-	-	-
MPHLCAIF_01890	3.93e-183	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MPHLCAIF_01891	4.5e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MPHLCAIF_01892	3.04e-258	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MPHLCAIF_01893	1.36e-265	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MPHLCAIF_01894	7.25e-28	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MPHLCAIF_01895	1.61e-30	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MPHLCAIF_01896	7.75e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MPHLCAIF_01898	6.92e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01899	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MPHLCAIF_01900	1.49e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MPHLCAIF_01901	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MPHLCAIF_01902	1.18e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MPHLCAIF_01903	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MPHLCAIF_01904	5.76e-212	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MPHLCAIF_01905	8.11e-222	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_01906	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
MPHLCAIF_01907	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MPHLCAIF_01908	8.08e-234	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MPHLCAIF_01909	1.58e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MPHLCAIF_01910	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MPHLCAIF_01911	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MPHLCAIF_01912	7.81e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MPHLCAIF_01913	7.1e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MPHLCAIF_01914	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MPHLCAIF_01915	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MPHLCAIF_01916	3.58e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MPHLCAIF_01917	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MPHLCAIF_01918	6.46e-265	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MPHLCAIF_01919	7.33e-270	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MPHLCAIF_01920	4.16e-200	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MPHLCAIF_01921	6.65e-280	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MPHLCAIF_01922	3.02e-171	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MPHLCAIF_01923	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MPHLCAIF_01924	4.74e-37	-	-	-	-	-	-	-	-
MPHLCAIF_01925	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MPHLCAIF_01927	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MPHLCAIF_01928	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MPHLCAIF_01929	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MPHLCAIF_01930	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MPHLCAIF_01931	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MPHLCAIF_01932	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MPHLCAIF_01933	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MPHLCAIF_01934	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MPHLCAIF_01935	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MPHLCAIF_01936	1.24e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MPHLCAIF_01937	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MPHLCAIF_01938	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_01939	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MPHLCAIF_01940	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MPHLCAIF_01941	7.89e-68	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MPHLCAIF_01943	1.12e-07	-	-	-	S	-	-	-	YopX protein
MPHLCAIF_01945	6.17e-60	-	-	-	S	-	-	-	dUTPase
MPHLCAIF_01951	2.78e-08	-	-	-	-	-	-	-	-
MPHLCAIF_01954	1.76e-10	-	-	-	-	-	-	-	-
MPHLCAIF_01955	1.04e-21	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MPHLCAIF_01956	1.81e-114	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
MPHLCAIF_01959	2.6e-09	-	-	-	T	ko:K21405	-	ko00000,ko03000	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MPHLCAIF_01960	9.99e-59	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MPHLCAIF_01963	5.28e-79	-	-	-	-	-	-	-	-
MPHLCAIF_01964	4.26e-43	-	-	-	S	-	-	-	Phage integrase family
MPHLCAIF_01965	2.09e-81	-	-	-	S	-	-	-	Phage integrase family
MPHLCAIF_01967	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MPHLCAIF_01968	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MPHLCAIF_01969	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MPHLCAIF_01970	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MPHLCAIF_01971	2.84e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
MPHLCAIF_01972	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
MPHLCAIF_01973	6.83e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MPHLCAIF_01974	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_01975	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
MPHLCAIF_01976	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_01977	9.2e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MPHLCAIF_01978	1.13e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MPHLCAIF_01979	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MPHLCAIF_01980	1.73e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MPHLCAIF_01981	1.9e-121	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MPHLCAIF_01982	9.67e-137	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MPHLCAIF_01983	6.08e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MPHLCAIF_01984	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MPHLCAIF_01985	3.23e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MPHLCAIF_01986	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MPHLCAIF_01987	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MPHLCAIF_01988	1.2e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
MPHLCAIF_01989	2.66e-155	yvbI	-	-	M	-	-	-	Membrane
MPHLCAIF_01990	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MPHLCAIF_01991	1.18e-97	yvbK	-	-	K	-	-	-	acetyltransferase
MPHLCAIF_01992	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MPHLCAIF_01993	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MPHLCAIF_01994	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MPHLCAIF_01995	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MPHLCAIF_01996	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MPHLCAIF_01997	4.01e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MPHLCAIF_01998	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_01999	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MPHLCAIF_02000	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MPHLCAIF_02001	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02002	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_02003	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_02004	2.7e-187	-	-	-	S	-	-	-	Glycosyl hydrolase
MPHLCAIF_02005	8.37e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MPHLCAIF_02006	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MPHLCAIF_02007	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MPHLCAIF_02008	2.52e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_02009	5.39e-252	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_02010	2.48e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MPHLCAIF_02011	5.7e-207	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MPHLCAIF_02012	8.25e-33	-	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	AAA domain
MPHLCAIF_02013	3.23e-178	-	-	-	M	-	-	-	-acetyltransferase
MPHLCAIF_02014	1.15e-66	-	-	-	S	-	-	-	ASCH
MPHLCAIF_02015	7.25e-201	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
MPHLCAIF_02016	1.89e-259	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
MPHLCAIF_02017	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MPHLCAIF_02018	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MPHLCAIF_02019	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MPHLCAIF_02020	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MPHLCAIF_02021	3.8e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MPHLCAIF_02022	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_02023	5.87e-147	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MPHLCAIF_02024	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MPHLCAIF_02025	4.25e-307	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MPHLCAIF_02026	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
MPHLCAIF_02027	5.09e-239	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MPHLCAIF_02028	1.5e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MPHLCAIF_02029	3.33e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MPHLCAIF_02030	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MPHLCAIF_02031	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_02032	5.49e-240	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MPHLCAIF_02033	1.83e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MPHLCAIF_02034	9.61e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MPHLCAIF_02035	7.25e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MPHLCAIF_02036	1.19e-276	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MPHLCAIF_02037	6.94e-199	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MPHLCAIF_02038	2.49e-278	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MPHLCAIF_02039	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MPHLCAIF_02040	1.6e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MPHLCAIF_02041	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MPHLCAIF_02042	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MPHLCAIF_02043	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MPHLCAIF_02045	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MPHLCAIF_02046	1.18e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MPHLCAIF_02047	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MPHLCAIF_02048	2.3e-158	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MPHLCAIF_02049	2.17e-224	pbpE	-	-	V	-	-	-	Beta-lactamase
MPHLCAIF_02050	3.77e-79	pbpE	-	-	V	-	-	-	Beta-lactamase
MPHLCAIF_02051	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MPHLCAIF_02052	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MPHLCAIF_02053	0.0	ybeC	-	-	E	-	-	-	amino acid
MPHLCAIF_02054	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02055	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MPHLCAIF_02056	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MPHLCAIF_02057	4.53e-95	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MPHLCAIF_02058	3.28e-29	-	-	-	K	-	-	-	Helix-turn-helix
MPHLCAIF_02060	2.94e-166	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MPHLCAIF_02061	1.27e-83	-	-	-	-	-	-	-	-
MPHLCAIF_02063	7.35e-46	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
MPHLCAIF_02064	2.24e-192	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MPHLCAIF_02065	1.85e-40	-	-	-	S	-	-	-	BhlA holin family
MPHLCAIF_02067	9.78e-54	yddC	-	-	-	-	-	-	-
MPHLCAIF_02068	9.78e-54	yddC	-	-	-	-	-	-	-
MPHLCAIF_02069	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MPHLCAIF_02070	1.82e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_02071	4.98e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MPHLCAIF_02072	1.16e-301	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MPHLCAIF_02074	4.47e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MPHLCAIF_02075	4.16e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MPHLCAIF_02076	7.68e-174	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MPHLCAIF_02077	2.91e-297	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MPHLCAIF_02078	2.99e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MPHLCAIF_02080	4.26e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02083	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MPHLCAIF_02087	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02088	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MPHLCAIF_02089	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MPHLCAIF_02090	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_02091	1.24e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02092	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MPHLCAIF_02093	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MPHLCAIF_02094	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MPHLCAIF_02095	3.05e-95	yvyF	-	-	S	-	-	-	flagellar protein
MPHLCAIF_02096	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MPHLCAIF_02097	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
MPHLCAIF_02098	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MPHLCAIF_02099	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MPHLCAIF_02100	6.92e-92	yviE	-	-	-	-	-	-	-
MPHLCAIF_02101	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MPHLCAIF_02102	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MPHLCAIF_02103	4.34e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MPHLCAIF_02104	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MPHLCAIF_02105	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MPHLCAIF_02106	1.48e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MPHLCAIF_02107	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MPHLCAIF_02108	2.46e-67	-	-	-	-	-	-	-	-
MPHLCAIF_02109	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MPHLCAIF_02110	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MPHLCAIF_02111	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MPHLCAIF_02112	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MPHLCAIF_02113	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MPHLCAIF_02114	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MPHLCAIF_02115	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MPHLCAIF_02116	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MPHLCAIF_02117	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
MPHLCAIF_02118	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPHLCAIF_02119	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
MPHLCAIF_02120	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02121	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MPHLCAIF_02122	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02123	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MPHLCAIF_02124	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MPHLCAIF_02125	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MPHLCAIF_02126	2.25e-45	yvkN	-	-	-	-	-	-	-
MPHLCAIF_02127	8.09e-65	yvlA	-	-	-	-	-	-	-
MPHLCAIF_02128	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
MPHLCAIF_02129	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MPHLCAIF_02130	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MPHLCAIF_02133	5.37e-22	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_02135	1.92e-145	-	-	-	S	-	-	-	Helix-turn-helix domain
MPHLCAIF_02136	6.09e-40	-	-	-	L	-	-	-	Phage integrase family
MPHLCAIF_02138	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MPHLCAIF_02139	4.39e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MPHLCAIF_02140	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MPHLCAIF_02141	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
MPHLCAIF_02142	1.02e-199	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MPHLCAIF_02143	2.29e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MPHLCAIF_02144	2.88e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MPHLCAIF_02145	2.83e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MPHLCAIF_02146	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MPHLCAIF_02147	6.55e-223	yvdE	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02148	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MPHLCAIF_02149	1.27e-39	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MPHLCAIF_02150	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MPHLCAIF_02151	1.07e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MPHLCAIF_02152	5.45e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MPHLCAIF_02153	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MPHLCAIF_02154	3.28e-181	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_02156	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MPHLCAIF_02157	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MPHLCAIF_02158	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MPHLCAIF_02159	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MPHLCAIF_02160	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MPHLCAIF_02161	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MPHLCAIF_02162	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MPHLCAIF_02163	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MPHLCAIF_02164	2.36e-111	yteJ	-	-	S	-	-	-	RDD family
MPHLCAIF_02165	4.62e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MPHLCAIF_02166	1.69e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MPHLCAIF_02167	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MPHLCAIF_02168	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MPHLCAIF_02169	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MPHLCAIF_02170	8.89e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MPHLCAIF_02171	2.74e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MPHLCAIF_02172	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MPHLCAIF_02173	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MPHLCAIF_02174	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MPHLCAIF_02175	9.83e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02176	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MPHLCAIF_02177	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MPHLCAIF_02178	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MPHLCAIF_02180	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MPHLCAIF_02181	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MPHLCAIF_02182	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MPHLCAIF_02183	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MPHLCAIF_02184	2.58e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MPHLCAIF_02185	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MPHLCAIF_02186	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MPHLCAIF_02187	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MPHLCAIF_02188	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MPHLCAIF_02189	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MPHLCAIF_02190	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MPHLCAIF_02191	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MPHLCAIF_02192	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MPHLCAIF_02193	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MPHLCAIF_02194	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MPHLCAIF_02195	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MPHLCAIF_02196	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MPHLCAIF_02197	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MPHLCAIF_02198	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MPHLCAIF_02199	6.75e-67	ytzB	-	-	S	-	-	-	small secreted protein
MPHLCAIF_02200	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MPHLCAIF_02201	3.18e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MPHLCAIF_02202	4.36e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MPHLCAIF_02203	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
MPHLCAIF_02204	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
MPHLCAIF_02205	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MPHLCAIF_02206	9.05e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MPHLCAIF_02207	4.92e-212	ytlQ	-	-	-	-	-	-	-
MPHLCAIF_02208	2.13e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MPHLCAIF_02209	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MPHLCAIF_02210	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MPHLCAIF_02211	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MPHLCAIF_02212	2.89e-254	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MPHLCAIF_02213	4.65e-167	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MPHLCAIF_02214	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MPHLCAIF_02215	2.13e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MPHLCAIF_02216	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_02217	1.16e-292	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MPHLCAIF_02218	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MPHLCAIF_02219	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MPHLCAIF_02220	9.57e-98	yteU	-	-	S	-	-	-	Integral membrane protein
MPHLCAIF_02221	1.83e-251	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MPHLCAIF_02222	2.27e-92	yteS	-	-	G	-	-	-	transport
MPHLCAIF_02223	4.8e-278	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MPHLCAIF_02224	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MPHLCAIF_02225	1.36e-202	ytdP	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02226	5.52e-276	ytdP	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02227	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MPHLCAIF_02228	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MPHLCAIF_02229	1.05e-176	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MPHLCAIF_02230	6.39e-279	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MPHLCAIF_02231	1.08e-242	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MPHLCAIF_02232	6.59e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MPHLCAIF_02233	2.83e-256	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MPHLCAIF_02234	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MPHLCAIF_02235	3.63e-151	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MPHLCAIF_02236	1.67e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
MPHLCAIF_02237	2.08e-240	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_02238	7.92e-307	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MPHLCAIF_02239	1.77e-198	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_02240	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MPHLCAIF_02241	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MPHLCAIF_02242	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MPHLCAIF_02243	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MPHLCAIF_02244	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MPHLCAIF_02245	1.49e-180	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MPHLCAIF_02246	4.05e-267	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_02247	5.75e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MPHLCAIF_02248	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MPHLCAIF_02249	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02250	1.3e-238	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MPHLCAIF_02251	9.07e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_02252	2.69e-294	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MPHLCAIF_02253	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02254	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MPHLCAIF_02255	4.66e-213	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_02256	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02257	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MPHLCAIF_02259	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MPHLCAIF_02260	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MPHLCAIF_02261	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MPHLCAIF_02262	2.78e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MPHLCAIF_02263	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MPHLCAIF_02264	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MPHLCAIF_02265	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_02266	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MPHLCAIF_02267	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MPHLCAIF_02268	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MPHLCAIF_02269	5.75e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MPHLCAIF_02270	9.48e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MPHLCAIF_02271	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MPHLCAIF_02272	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MPHLCAIF_02273	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MPHLCAIF_02274	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MPHLCAIF_02275	1.59e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MPHLCAIF_02276	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MPHLCAIF_02278	6.79e-95	ytkA	-	-	S	-	-	-	YtkA-like
MPHLCAIF_02279	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MPHLCAIF_02280	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MPHLCAIF_02281	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MPHLCAIF_02282	3e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MPHLCAIF_02283	4.02e-239	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MPHLCAIF_02284	9.9e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MPHLCAIF_02285	7.59e-191	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MPHLCAIF_02286	5.85e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MPHLCAIF_02287	9.74e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MPHLCAIF_02288	3.77e-217	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MPHLCAIF_02289	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MPHLCAIF_02290	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MPHLCAIF_02291	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MPHLCAIF_02292	4.49e-193	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MPHLCAIF_02293	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MPHLCAIF_02294	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MPHLCAIF_02295	8.68e-169	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MPHLCAIF_02296	2.32e-194	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MPHLCAIF_02297	6.8e-309	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MPHLCAIF_02298	7.97e-224	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
MPHLCAIF_02299	7.32e-292	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
MPHLCAIF_02301	6.65e-261	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
MPHLCAIF_02302	1.61e-272	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
MPHLCAIF_02303	3.68e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
MPHLCAIF_02304	1.75e-95	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MPHLCAIF_02305	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MPHLCAIF_02306	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MPHLCAIF_02307	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
MPHLCAIF_02308	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MPHLCAIF_02309	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MPHLCAIF_02326	8.73e-109	-	-	-	L	-	-	-	Domain of unknown function (DUF1738)
MPHLCAIF_02329	3.45e-48	nucH	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	COG1525 Micrococcal nuclease (thermonuclease) homologs
MPHLCAIF_02332	1.32e-151	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
MPHLCAIF_02338	2.28e-53	-	-	-	L	-	-	-	Site-specific recombinase, phage integrase family
MPHLCAIF_02341	4.64e-65	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MPHLCAIF_02343	2.5e-06	rok	-	-	S	-	-	-	Repressor of ComK
MPHLCAIF_02347	2.51e-49	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MPHLCAIF_02349	1.86e-111	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
MPHLCAIF_02353	9.35e-69	yddH	-	-	M	-	-	-	Lysozyme-like
MPHLCAIF_02355	5.71e-216	-	-	-	S	-	-	-	AAA-like domain
MPHLCAIF_02356	1.47e-47	-	-	-	-	-	-	-	-
MPHLCAIF_02358	4.33e-50	-	-	-	S	-	-	-	domain, Protein
MPHLCAIF_02359	4.48e-214	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MPHLCAIF_02367	3.88e-34	-	-	-	-	-	-	-	-
MPHLCAIF_02368	4.26e-66	-	-	-	-	-	-	-	-
MPHLCAIF_02369	4.6e-99	-	-	-	-	-	-	-	-
MPHLCAIF_02370	1.43e-138	-	-	-	NU	ko:K02283	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MPHLCAIF_02374	1.64e-278	-	-	-	M	-	-	-	domain protein
MPHLCAIF_02377	2.47e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF5052)
MPHLCAIF_02381	0.000863	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_02383	6.01e-61	-	-	-	K	-	-	-	COG0457 FOG TPR repeat
MPHLCAIF_02384	1.4e-193	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
MPHLCAIF_02389	8.02e-30	-	-	-	V	-	-	-	VanZ like family
MPHLCAIF_02391	3.15e-36	-	-	-	-	-	-	-	-
MPHLCAIF_02392	4.3e-201	-	-	-	S	-	-	-	damaged DNA binding
MPHLCAIF_02406	1.89e-40	-	-	-	-	-	-	-	-
MPHLCAIF_02407	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
MPHLCAIF_02412	5.24e-60	-	-	-	-	-	-	-	-
MPHLCAIF_02413	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
MPHLCAIF_02414	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MPHLCAIF_02416	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MPHLCAIF_02417	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MPHLCAIF_02418	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MPHLCAIF_02419	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
MPHLCAIF_02421	8.28e-87	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
MPHLCAIF_02422	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02423	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MPHLCAIF_02424	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_02425	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MPHLCAIF_02426	7.4e-168	-	-	-	-	-	-	-	-
MPHLCAIF_02427	2.98e-214	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
MPHLCAIF_02428	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MPHLCAIF_02429	1.44e-177	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_02430	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MPHLCAIF_02432	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MPHLCAIF_02433	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MPHLCAIF_02434	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MPHLCAIF_02435	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MPHLCAIF_02436	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MPHLCAIF_02437	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MPHLCAIF_02438	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MPHLCAIF_02439	5.44e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
MPHLCAIF_02440	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MPHLCAIF_02441	3.85e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MPHLCAIF_02442	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MPHLCAIF_02443	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MPHLCAIF_02444	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
MPHLCAIF_02445	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MPHLCAIF_02446	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MPHLCAIF_02447	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MPHLCAIF_02448	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MPHLCAIF_02449	2.28e-66	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MPHLCAIF_02450	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MPHLCAIF_02451	5.86e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MPHLCAIF_02452	3.88e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MPHLCAIF_02453	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MPHLCAIF_02454	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MPHLCAIF_02455	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MPHLCAIF_02456	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MPHLCAIF_02457	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MPHLCAIF_02458	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MPHLCAIF_02459	3.26e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MPHLCAIF_02460	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MPHLCAIF_02461	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MPHLCAIF_02462	3.78e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MPHLCAIF_02463	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
MPHLCAIF_02464	2.23e-56	yqfB	-	-	-	-	-	-	-
MPHLCAIF_02465	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MPHLCAIF_02466	8.52e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MPHLCAIF_02467	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MPHLCAIF_02469	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MPHLCAIF_02470	1.75e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MPHLCAIF_02471	3.34e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MPHLCAIF_02472	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MPHLCAIF_02473	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MPHLCAIF_02474	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
MPHLCAIF_02475	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MPHLCAIF_02476	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MPHLCAIF_02477	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MPHLCAIF_02478	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
MPHLCAIF_02479	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MPHLCAIF_02480	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MPHLCAIF_02481	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MPHLCAIF_02482	2.29e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MPHLCAIF_02483	2.29e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MPHLCAIF_02484	5.67e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MPHLCAIF_02485	4.21e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MPHLCAIF_02486	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MPHLCAIF_02487	3.73e-46	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MPHLCAIF_02488	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MPHLCAIF_02489	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MPHLCAIF_02490	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MPHLCAIF_02491	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MPHLCAIF_02492	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MPHLCAIF_02493	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MPHLCAIF_02494	2.38e-80	yqfX	-	-	S	-	-	-	membrane
MPHLCAIF_02495	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MPHLCAIF_02496	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MPHLCAIF_02497	1.58e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MPHLCAIF_02498	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MPHLCAIF_02499	1.31e-147	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MPHLCAIF_02500	1.09e-290	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MPHLCAIF_02501	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MPHLCAIF_02502	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MPHLCAIF_02503	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MPHLCAIF_02504	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MPHLCAIF_02505	1.14e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MPHLCAIF_02506	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MPHLCAIF_02507	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
MPHLCAIF_02508	2.81e-67	yqzD	-	-	-	-	-	-	-
MPHLCAIF_02510	1.94e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
MPHLCAIF_02511	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MPHLCAIF_02512	4.62e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MPHLCAIF_02513	3.38e-14	yqgO	-	-	-	-	-	-	-
MPHLCAIF_02514	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MPHLCAIF_02515	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MPHLCAIF_02516	3.28e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MPHLCAIF_02517	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MPHLCAIF_02518	3.55e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MPHLCAIF_02519	2.69e-256	yqgU	-	-	-	-	-	-	-
MPHLCAIF_02520	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MPHLCAIF_02521	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MPHLCAIF_02522	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MPHLCAIF_02523	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MPHLCAIF_02524	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MPHLCAIF_02526	4.82e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MPHLCAIF_02527	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MPHLCAIF_02528	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MPHLCAIF_02529	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MPHLCAIF_02530	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MPHLCAIF_02531	7.16e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MPHLCAIF_02532	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MPHLCAIF_02533	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
MPHLCAIF_02534	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MPHLCAIF_02535	1.01e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MPHLCAIF_02536	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MPHLCAIF_02537	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
MPHLCAIF_02538	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MPHLCAIF_02539	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
MPHLCAIF_02540	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MPHLCAIF_02541	3.67e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MPHLCAIF_02542	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MPHLCAIF_02543	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MPHLCAIF_02544	1.52e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MPHLCAIF_02545	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MPHLCAIF_02546	2.72e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MPHLCAIF_02547	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MPHLCAIF_02548	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MPHLCAIF_02549	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MPHLCAIF_02550	1.07e-202	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MPHLCAIF_02551	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MPHLCAIF_02552	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MPHLCAIF_02553	5.18e-81	yqhP	-	-	-	-	-	-	-
MPHLCAIF_02554	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MPHLCAIF_02555	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MPHLCAIF_02556	1.94e-100	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MPHLCAIF_02557	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MPHLCAIF_02558	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MPHLCAIF_02559	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MPHLCAIF_02560	2.46e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MPHLCAIF_02561	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MPHLCAIF_02562	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MPHLCAIF_02563	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MPHLCAIF_02564	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MPHLCAIF_02565	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MPHLCAIF_02566	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MPHLCAIF_02567	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MPHLCAIF_02568	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MPHLCAIF_02570	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
MPHLCAIF_02571	2.43e-14	-	-	-	-	-	-	-	-
MPHLCAIF_02574	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MPHLCAIF_02577	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MPHLCAIF_02578	1.4e-264	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_02579	8.79e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MPHLCAIF_02580	6.17e-299	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MPHLCAIF_02581	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
MPHLCAIF_02582	3.17e-212	yrdR	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_02583	1.4e-203	-	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02584	5e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MPHLCAIF_02585	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MPHLCAIF_02587	9.63e-290	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MPHLCAIF_02588	2.79e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MPHLCAIF_02589	2.1e-117	azlC	-	-	E	-	-	-	AzlC protein
MPHLCAIF_02590	4.45e-99	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
MPHLCAIF_02591	3.92e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MPHLCAIF_02592	1.16e-284	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MPHLCAIF_02594	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
MPHLCAIF_02595	1.09e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
MPHLCAIF_02597	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
MPHLCAIF_02598	1.48e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MPHLCAIF_02599	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MPHLCAIF_02600	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MPHLCAIF_02601	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MPHLCAIF_02603	6.26e-168	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MPHLCAIF_02604	3.7e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_02605	5.72e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
MPHLCAIF_02606	2.2e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MPHLCAIF_02607	8.42e-55	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_02608	1.05e-178	-	-	-	S	-	-	-	Alpha beta hydrolase
MPHLCAIF_02609	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
MPHLCAIF_02610	1.05e-81	-	-	-	T	-	-	-	sh3 domain protein
MPHLCAIF_02611	1.1e-85	-	-	-	E	-	-	-	Glyoxalase-like domain
MPHLCAIF_02612	4.04e-48	yraG	-	-	-	ko:K06440	-	ko00000	-
MPHLCAIF_02613	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
MPHLCAIF_02614	3.71e-283	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MPHLCAIF_02615	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
MPHLCAIF_02616	4.9e-64	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MPHLCAIF_02617	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MPHLCAIF_02618	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
MPHLCAIF_02619	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MPHLCAIF_02620	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MPHLCAIF_02621	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MPHLCAIF_02622	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MPHLCAIF_02623	1.75e-167	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MPHLCAIF_02624	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
MPHLCAIF_02625	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
MPHLCAIF_02626	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
MPHLCAIF_02627	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_02628	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
MPHLCAIF_02629	3.41e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
MPHLCAIF_02630	5.77e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_02631	2.88e-190	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MPHLCAIF_02632	2.18e-84	oatA	-	-	I	-	-	-	Acyltransferase family
MPHLCAIF_02633	3.76e-287	oatA	-	-	I	-	-	-	Acyltransferase family
MPHLCAIF_02634	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
MPHLCAIF_02635	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MPHLCAIF_02636	2.35e-201	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MPHLCAIF_02637	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MPHLCAIF_02638	4.3e-124	yrhH	-	-	Q	-	-	-	methyltransferase
MPHLCAIF_02639	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MPHLCAIF_02640	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MPHLCAIF_02642	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MPHLCAIF_02643	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MPHLCAIF_02644	2.46e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MPHLCAIF_02646	1.79e-74	-	-	-	S	-	-	-	Bacteriophage holin family
MPHLCAIF_02647	6.14e-142	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_02650	1.55e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MPHLCAIF_02653	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_02654	7.02e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MPHLCAIF_02655	5.85e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MPHLCAIF_02656	1.01e-64	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MPHLCAIF_02657	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MPHLCAIF_02658	4.87e-34	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MPHLCAIF_02659	8.02e-107	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MPHLCAIF_02660	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MPHLCAIF_02661	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MPHLCAIF_02662	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
MPHLCAIF_02663	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MPHLCAIF_02664	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MPHLCAIF_02665	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
MPHLCAIF_02666	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MPHLCAIF_02667	2.34e-139	yvgT	-	-	S	-	-	-	membrane
MPHLCAIF_02669	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MPHLCAIF_02670	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MPHLCAIF_02671	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MPHLCAIF_02672	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MPHLCAIF_02673	9.32e-112	yvgO	-	-	-	-	-	-	-
MPHLCAIF_02674	7.23e-200	yvgN	-	-	S	-	-	-	reductase
MPHLCAIF_02675	1.74e-153	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MPHLCAIF_02676	6.03e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MPHLCAIF_02677	3.46e-212	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MPHLCAIF_02678	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MPHLCAIF_02679	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MPHLCAIF_02680	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MPHLCAIF_02681	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MPHLCAIF_02682	4.45e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_02683	3.87e-233	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_02684	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_02685	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MPHLCAIF_02686	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
MPHLCAIF_02687	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02688	2.21e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MPHLCAIF_02689	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MPHLCAIF_02690	3.76e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MPHLCAIF_02691	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
MPHLCAIF_02692	6.67e-125	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MPHLCAIF_02693	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_02694	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MPHLCAIF_02695	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MPHLCAIF_02696	1.01e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_02697	7.32e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MPHLCAIF_02698	7.73e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MPHLCAIF_02699	5.43e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MPHLCAIF_02700	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MPHLCAIF_02701	1.53e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_02702	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MPHLCAIF_02703	1.41e-142	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MPHLCAIF_02704	8.15e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MPHLCAIF_02705	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MPHLCAIF_02706	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_02707	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_02708	5.54e-234	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MPHLCAIF_02709	7.95e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MPHLCAIF_02710	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MPHLCAIF_02711	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MPHLCAIF_02712	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MPHLCAIF_02713	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02714	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_02715	6.4e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_02716	2.17e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPHLCAIF_02717	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MPHLCAIF_02718	2.71e-176	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_02719	5.75e-160	-	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MPHLCAIF_02720	1.26e-18	-	-	-	-	-	-	-	-
MPHLCAIF_02722	3.05e-20	-	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
MPHLCAIF_02724	2.94e-17	-	-	-	EGP	-	-	-	Major Facilitator
MPHLCAIF_02725	6.4e-09	-	-	-	J	-	-	-	O-methyltransferase
MPHLCAIF_02726	3.54e-95	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC superfamily ATP binding cassette transporter ABC protein
MPHLCAIF_02727	2.98e-14	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MPHLCAIF_02729	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MPHLCAIF_02730	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
MPHLCAIF_02731	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MPHLCAIF_02732	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MPHLCAIF_02733	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
MPHLCAIF_02734	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_02735	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
MPHLCAIF_02736	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MPHLCAIF_02737	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MPHLCAIF_02738	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
MPHLCAIF_02739	2.23e-54	-	-	-	-	-	-	-	-
MPHLCAIF_02740	1.41e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MPHLCAIF_02741	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
MPHLCAIF_02742	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MPHLCAIF_02743	3.15e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MPHLCAIF_02744	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MPHLCAIF_02745	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MPHLCAIF_02746	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MPHLCAIF_02747	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MPHLCAIF_02748	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MPHLCAIF_02749	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
MPHLCAIF_02750	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MPHLCAIF_02751	1.76e-235	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MPHLCAIF_02752	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MPHLCAIF_02753	1.01e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MPHLCAIF_02754	6.44e-62	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MPHLCAIF_02755	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MPHLCAIF_02756	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MPHLCAIF_02757	1.63e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MPHLCAIF_02758	1.79e-100	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MPHLCAIF_02759	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MPHLCAIF_02760	1.25e-56	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MPHLCAIF_02761	2.06e-85	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_02762	3.35e-56	-	-	-	-	-	-	-	-
MPHLCAIF_02764	3.9e-266	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MPHLCAIF_02765	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MPHLCAIF_02766	3.71e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MPHLCAIF_02767	1e-307	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MPHLCAIF_02768	2.05e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MPHLCAIF_02769	1.29e-89	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MPHLCAIF_02770	4.53e-107	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MPHLCAIF_02771	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MPHLCAIF_02772	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MPHLCAIF_02773	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_02774	7.63e-217	bsn	-	-	L	-	-	-	Ribonuclease
MPHLCAIF_02775	6.85e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MPHLCAIF_02776	9.52e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MPHLCAIF_02777	5.27e-236	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MPHLCAIF_02778	8.43e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MPHLCAIF_02779	6.07e-188	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MPHLCAIF_02780	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MPHLCAIF_02781	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MPHLCAIF_02782	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MPHLCAIF_02783	8.84e-74	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MPHLCAIF_02784	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MPHLCAIF_02785	3.71e-282	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
MPHLCAIF_02786	1.7e-297	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
MPHLCAIF_02787	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MPHLCAIF_02788	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MPHLCAIF_02789	3.06e-79	yunG	-	-	-	-	-	-	-
MPHLCAIF_02790	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MPHLCAIF_02791	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MPHLCAIF_02792	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MPHLCAIF_02793	5.67e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MPHLCAIF_02794	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MPHLCAIF_02795	1.08e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MPHLCAIF_02796	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MPHLCAIF_02797	2.71e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MPHLCAIF_02798	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02799	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MPHLCAIF_02800	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MPHLCAIF_02801	3.34e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MPHLCAIF_02802	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
MPHLCAIF_02803	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MPHLCAIF_02804	3.97e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MPHLCAIF_02805	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MPHLCAIF_02806	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MPHLCAIF_02807	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MPHLCAIF_02808	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02809	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MPHLCAIF_02810	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MPHLCAIF_02811	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MPHLCAIF_02812	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MPHLCAIF_02813	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MPHLCAIF_02814	7.01e-128	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MPHLCAIF_02815	3.64e-138	-	-	-	S	-	-	-	Helix-turn-helix domain
MPHLCAIF_02816	1.36e-87	-	-	-	L	-	-	-	Integrase
MPHLCAIF_02817	1.04e-05	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_02820	3.91e-135	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
MPHLCAIF_02822	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MPHLCAIF_02824	9.49e-89	-	-	-	-	-	-	-	-
MPHLCAIF_02825	2.58e-297	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MPHLCAIF_02827	1.58e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MPHLCAIF_02828	4.42e-254	yycP	-	-	-	-	-	-	-
MPHLCAIF_02829	7.97e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MPHLCAIF_02830	3.04e-110	yycN	-	-	K	-	-	-	Acetyltransferase
MPHLCAIF_02831	8.7e-239	-	-	-	S	-	-	-	aspartate phosphatase
MPHLCAIF_02833	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MPHLCAIF_02834	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MPHLCAIF_02835	1.01e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MPHLCAIF_02836	5.82e-20	-	-	-	-	-	-	-	-
MPHLCAIF_02837	4.85e-119	-	-	-	-	-	-	-	-
MPHLCAIF_02838	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
MPHLCAIF_02839	3.95e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MPHLCAIF_02840	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
MPHLCAIF_02841	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MPHLCAIF_02842	9.43e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPHLCAIF_02843	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MPHLCAIF_02844	3.44e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02845	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02846	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_02847	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_02852	1.75e-312	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MPHLCAIF_02853	3.17e-97	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_02854	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MPHLCAIF_02855	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MPHLCAIF_02857	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
MPHLCAIF_02858	1.15e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MPHLCAIF_02859	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MPHLCAIF_02860	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MPHLCAIF_02861	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MPHLCAIF_02862	1.5e-204	yybS	-	-	S	-	-	-	membrane
MPHLCAIF_02864	6.16e-20	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MPHLCAIF_02865	1.71e-67	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MPHLCAIF_02866	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02867	1.4e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MPHLCAIF_02868	1.11e-90	-	-	-	-	-	-	-	-
MPHLCAIF_02870	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_02871	9.88e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
MPHLCAIF_02872	2.05e-183	-	-	-	-	-	-	-	-
MPHLCAIF_02873	2.39e-85	-	-	-	S	-	-	-	SnoaL-like domain
MPHLCAIF_02874	2.81e-162	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MPHLCAIF_02875	6.02e-127	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_02876	2.04e-88	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MPHLCAIF_02877	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
MPHLCAIF_02878	2.44e-94	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_02879	1.01e-123	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MPHLCAIF_02880	4.7e-120	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MPHLCAIF_02881	1.5e-85	-	-	-	S	-	-	-	YjbR
MPHLCAIF_02882	8.28e-135	yyaP	-	-	H	-	-	-	RibD C-terminal domain
MPHLCAIF_02883	2.59e-36	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MPHLCAIF_02884	3.47e-108	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MPHLCAIF_02885	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MPHLCAIF_02886	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MPHLCAIF_02887	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
MPHLCAIF_02888	3.43e-81	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MPHLCAIF_02889	8.75e-26	-	-	-	H	-	-	-	ThiF family
MPHLCAIF_02890	1.15e-30	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MPHLCAIF_02891	3.58e-50	-	-	-	EGP	-	-	-	PFAM Major Facilitator Superfamily
MPHLCAIF_02892	5.01e-78	ccpB	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_02893	1.15e-184	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MPHLCAIF_02894	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MPHLCAIF_02895	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MPHLCAIF_02896	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MPHLCAIF_02897	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MPHLCAIF_02898	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MPHLCAIF_02899	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02900	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
MPHLCAIF_02901	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MPHLCAIF_02902	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MPHLCAIF_02903	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MPHLCAIF_02904	3.77e-97	-	-	-	S	-	-	-	Bacterial PH domain
MPHLCAIF_02905	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MPHLCAIF_02906	2.9e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MPHLCAIF_02907	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MPHLCAIF_02908	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MPHLCAIF_02909	2.14e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MPHLCAIF_02910	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MPHLCAIF_02911	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MPHLCAIF_02912	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MPHLCAIF_02913	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MPHLCAIF_02914	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MPHLCAIF_02915	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MPHLCAIF_02916	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MPHLCAIF_02917	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPHLCAIF_02918	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MPHLCAIF_02919	7.78e-114	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MPHLCAIF_02920	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MPHLCAIF_02921	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
MPHLCAIF_02922	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MPHLCAIF_02923	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MPHLCAIF_02924	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_02925	1.36e-32	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
MPHLCAIF_02926	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MPHLCAIF_02927	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MPHLCAIF_02928	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MPHLCAIF_02929	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MPHLCAIF_02930	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MPHLCAIF_02931	1.73e-64	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MPHLCAIF_02932	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MPHLCAIF_02933	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02934	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MPHLCAIF_02935	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MPHLCAIF_02936	6.92e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MPHLCAIF_02937	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MPHLCAIF_02938	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MPHLCAIF_02939	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MPHLCAIF_02940	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MPHLCAIF_02941	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MPHLCAIF_02942	1.16e-305	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MPHLCAIF_02943	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MPHLCAIF_02944	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MPHLCAIF_02946	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MPHLCAIF_02947	1.46e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MPHLCAIF_02948	1.08e-188	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MPHLCAIF_02949	8.17e-25	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
MPHLCAIF_02950	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MPHLCAIF_02951	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_02952	4.82e-196	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MPHLCAIF_02953	2.79e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MPHLCAIF_02954	2.63e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MPHLCAIF_02955	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MPHLCAIF_02956	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MPHLCAIF_02958	1.33e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MPHLCAIF_02959	5.85e-165	yebC	-	-	M	-	-	-	Membrane
MPHLCAIF_02961	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MPHLCAIF_02962	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
MPHLCAIF_02963	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MPHLCAIF_02964	2.69e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MPHLCAIF_02965	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MPHLCAIF_02966	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MPHLCAIF_02967	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPHLCAIF_02968	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPHLCAIF_02969	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MPHLCAIF_02970	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MPHLCAIF_02971	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MPHLCAIF_02972	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MPHLCAIF_02973	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MPHLCAIF_02974	5.45e-296	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MPHLCAIF_02975	1.11e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MPHLCAIF_02976	1.87e-288	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MPHLCAIF_02977	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MPHLCAIF_02978	1.25e-239	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MPHLCAIF_02979	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_02980	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MPHLCAIF_02982	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MPHLCAIF_02983	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MPHLCAIF_02984	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MPHLCAIF_02985	3.57e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MPHLCAIF_02987	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MPHLCAIF_02988	1.05e-179	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_02989	1.38e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MPHLCAIF_02990	3.69e-169	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_02991	2.3e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MPHLCAIF_02992	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MPHLCAIF_02993	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MPHLCAIF_02994	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MPHLCAIF_02995	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MPHLCAIF_02996	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MPHLCAIF_02997	3.89e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MPHLCAIF_02998	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MPHLCAIF_02999	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MPHLCAIF_03000	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MPHLCAIF_03002	0.0	-	-	-	-	-	-	-	-
MPHLCAIF_03003	1.29e-111	-	-	-	-	-	-	-	-
MPHLCAIF_03004	2.93e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MPHLCAIF_03005	3.97e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MPHLCAIF_03006	4.61e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MPHLCAIF_03007	3.29e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MPHLCAIF_03008	2.02e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MPHLCAIF_03009	1.81e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MPHLCAIF_03010	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MPHLCAIF_03011	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MPHLCAIF_03012	4.31e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MPHLCAIF_03013	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
MPHLCAIF_03014	8.97e-56	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03016	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MPHLCAIF_03017	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
MPHLCAIF_03018	8.73e-09	yuzC	-	-	-	-	-	-	-
MPHLCAIF_03019	1.97e-296	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MPHLCAIF_03020	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MPHLCAIF_03021	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MPHLCAIF_03022	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MPHLCAIF_03023	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
MPHLCAIF_03024	6.9e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MPHLCAIF_03025	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
MPHLCAIF_03026	3.97e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
MPHLCAIF_03027	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MPHLCAIF_03028	6.1e-171	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_03029	4.37e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MPHLCAIF_03030	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MPHLCAIF_03031	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MPHLCAIF_03032	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MPHLCAIF_03033	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MPHLCAIF_03034	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MPHLCAIF_03035	1.71e-291	yukF	-	-	QT	-	-	-	Transcriptional regulator
MPHLCAIF_03036	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MPHLCAIF_03037	2.42e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MPHLCAIF_03038	8.23e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MPHLCAIF_03039	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_03040	1.82e-227	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MPHLCAIF_03041	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MPHLCAIF_03042	1.22e-289	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MPHLCAIF_03043	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_03044	2.18e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MPHLCAIF_03045	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MPHLCAIF_03046	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MPHLCAIF_03047	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MPHLCAIF_03048	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MPHLCAIF_03049	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MPHLCAIF_03050	2.69e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03051	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
MPHLCAIF_03052	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MPHLCAIF_03053	6.7e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MPHLCAIF_03055	6.4e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MPHLCAIF_03056	8.15e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
MPHLCAIF_03057	2.31e-114	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_03059	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
MPHLCAIF_03066	5.32e-26	-	-	-	-	-	-	-	-
MPHLCAIF_03067	5.48e-110	-	-	-	-	-	-	-	-
MPHLCAIF_03071	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MPHLCAIF_03072	6.08e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MPHLCAIF_03073	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MPHLCAIF_03074	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MPHLCAIF_03075	1.34e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MPHLCAIF_03076	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03077	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MPHLCAIF_03078	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MPHLCAIF_03079	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MPHLCAIF_03080	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MPHLCAIF_03081	2.81e-178	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MPHLCAIF_03082	4.19e-65	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MPHLCAIF_03083	7.26e-208	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MPHLCAIF_03084	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MPHLCAIF_03085	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MPHLCAIF_03086	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MPHLCAIF_03087	1.91e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
MPHLCAIF_03088	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MPHLCAIF_03089	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MPHLCAIF_03090	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MPHLCAIF_03091	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03092	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MPHLCAIF_03093	9.53e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MPHLCAIF_03094	3.82e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MPHLCAIF_03095	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MPHLCAIF_03096	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MPHLCAIF_03097	1.49e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MPHLCAIF_03098	3.51e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MPHLCAIF_03099	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MPHLCAIF_03100	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MPHLCAIF_03101	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MPHLCAIF_03102	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MPHLCAIF_03103	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MPHLCAIF_03104	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_03105	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MPHLCAIF_03106	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MPHLCAIF_03107	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MPHLCAIF_03108	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MPHLCAIF_03109	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MPHLCAIF_03110	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MPHLCAIF_03113	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MPHLCAIF_03114	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MPHLCAIF_03115	3.83e-233	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MPHLCAIF_03116	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MPHLCAIF_03117	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MPHLCAIF_03118	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MPHLCAIF_03119	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MPHLCAIF_03120	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MPHLCAIF_03121	4.17e-205	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MPHLCAIF_03122	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MPHLCAIF_03123	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MPHLCAIF_03124	4.92e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MPHLCAIF_03125	1.32e-215	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MPHLCAIF_03126	3.19e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MPHLCAIF_03127	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MPHLCAIF_03128	7.57e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MPHLCAIF_03129	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
MPHLCAIF_03130	7.88e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MPHLCAIF_03131	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MPHLCAIF_03132	1.94e-180	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
MPHLCAIF_03133	1.03e-237	yddH	-	-	M	-	-	-	Lysozyme-like
MPHLCAIF_03134	3.19e-111	yddI	-	-	-	-	-	-	-
MPHLCAIF_03135	3.04e-87	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MPHLCAIF_03136	2.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
MPHLCAIF_03137	2.45e-83	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_03139	9.39e-63	yhcM	-	-	-	-	-	-	-
MPHLCAIF_03140	6e-104	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MPHLCAIF_03141	1.01e-217	yhcP	-	-	-	-	-	-	-
MPHLCAIF_03142	8.34e-128	yhcQ	-	-	M	-	-	-	Spore coat protein
MPHLCAIF_03143	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MPHLCAIF_03144	1.25e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MPHLCAIF_03145	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MPHLCAIF_03146	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MPHLCAIF_03147	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MPHLCAIF_03148	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MPHLCAIF_03149	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MPHLCAIF_03150	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MPHLCAIF_03151	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MPHLCAIF_03152	4.68e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MPHLCAIF_03153	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MPHLCAIF_03154	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MPHLCAIF_03155	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MPHLCAIF_03156	1.27e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03157	1.15e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_03158	2.7e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MPHLCAIF_03159	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MPHLCAIF_03160	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MPHLCAIF_03161	2.22e-35	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MPHLCAIF_03162	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
MPHLCAIF_03163	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
MPHLCAIF_03164	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MPHLCAIF_03165	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MPHLCAIF_03166	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MPHLCAIF_03167	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MPHLCAIF_03168	1.89e-211	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MPHLCAIF_03169	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MPHLCAIF_03170	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MPHLCAIF_03171	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
MPHLCAIF_03172	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MPHLCAIF_03173	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MPHLCAIF_03174	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MPHLCAIF_03175	3.86e-237	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MPHLCAIF_03176	0.0	ykoS	-	-	-	-	-	-	-
MPHLCAIF_03177	1.2e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MPHLCAIF_03178	2.57e-122	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MPHLCAIF_03179	6.33e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MPHLCAIF_03180	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MPHLCAIF_03181	3.04e-36	ykoL	-	-	-	-	-	-	-
MPHLCAIF_03182	1.63e-25	-	-	-	-	-	-	-	-
MPHLCAIF_03183	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
MPHLCAIF_03184	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MPHLCAIF_03186	1.45e-08	-	-	-	-	-	-	-	-
MPHLCAIF_03187	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MPHLCAIF_03188	7.88e-145	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MPHLCAIF_03189	6.32e-309	ykoH	-	-	T	-	-	-	Histidine kinase
MPHLCAIF_03190	1.28e-160	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MPHLCAIF_03191	1.21e-142	ykoF	-	-	S	-	-	-	YKOF-related Family
MPHLCAIF_03192	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MPHLCAIF_03193	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_03194	3.65e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MPHLCAIF_03195	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MPHLCAIF_03196	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MPHLCAIF_03197	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MPHLCAIF_03198	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MPHLCAIF_03199	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MPHLCAIF_03200	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MPHLCAIF_03201	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MPHLCAIF_03202	2.86e-260	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MPHLCAIF_03203	0.000977	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MPHLCAIF_03204	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MPHLCAIF_03205	2.76e-216	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MPHLCAIF_03206	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MPHLCAIF_03207	2.99e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MPHLCAIF_03208	2.43e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MPHLCAIF_03209	2.51e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MPHLCAIF_03210	1.32e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MPHLCAIF_03211	9.93e-15	-	-	-	-	-	-	-	-
MPHLCAIF_03212	4.21e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MPHLCAIF_03213	5.42e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MPHLCAIF_03214	9.79e-102	ykgA	-	-	E	-	-	-	Amidinotransferase
MPHLCAIF_03215	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MPHLCAIF_03216	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03217	4.03e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MPHLCAIF_03218	3.21e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MPHLCAIF_03219	5.33e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MPHLCAIF_03221	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MPHLCAIF_03222	7.78e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03223	1.23e-223	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03224	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03225	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MPHLCAIF_03226	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
MPHLCAIF_03227	2.73e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MPHLCAIF_03229	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MPHLCAIF_03230	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MPHLCAIF_03231	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MPHLCAIF_03232	1.81e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MPHLCAIF_03233	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MPHLCAIF_03234	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MPHLCAIF_03235	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MPHLCAIF_03236	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MPHLCAIF_03237	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_03238	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
MPHLCAIF_03239	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MPHLCAIF_03240	9.79e-195	xepA	-	-	-	-	-	-	-
MPHLCAIF_03241	6.35e-31	xkdX	-	-	-	-	-	-	-
MPHLCAIF_03242	2.7e-68	xkdW	-	-	S	-	-	-	XkdW protein
MPHLCAIF_03243	0.0	-	-	-	-	-	-	-	-
MPHLCAIF_03244	4.43e-56	-	-	-	-	-	-	-	-
MPHLCAIF_03245	3.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MPHLCAIF_03246	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MPHLCAIF_03247	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MPHLCAIF_03248	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MPHLCAIF_03249	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
MPHLCAIF_03250	1.73e-151	xkdP	-	-	S	-	-	-	Lysin motif
MPHLCAIF_03251	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MPHLCAIF_03252	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MPHLCAIF_03253	2.45e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
MPHLCAIF_03254	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MPHLCAIF_03255	2.36e-100	xkdJ	-	-	-	-	-	-	-
MPHLCAIF_03256	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MPHLCAIF_03257	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
MPHLCAIF_03258	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MPHLCAIF_03259	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
MPHLCAIF_03260	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MPHLCAIF_03261	0.0	yqbA	-	-	S	-	-	-	portal protein
MPHLCAIF_03262	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MPHLCAIF_03263	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MPHLCAIF_03264	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MPHLCAIF_03268	4.14e-150	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MPHLCAIF_03269	2.52e-201	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MPHLCAIF_03271	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MPHLCAIF_03272	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MPHLCAIF_03273	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MPHLCAIF_03274	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
MPHLCAIF_03275	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
MPHLCAIF_03276	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MPHLCAIF_03277	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
MPHLCAIF_03279	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_03280	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MPHLCAIF_03281	4.85e-182	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MPHLCAIF_03282	8.95e-225	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
MPHLCAIF_03283	7.75e-232	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MPHLCAIF_03284	1.29e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MPHLCAIF_03285	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MPHLCAIF_03286	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MPHLCAIF_03287	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPHLCAIF_03288	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MPHLCAIF_03289	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
MPHLCAIF_03290	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
MPHLCAIF_03291	7.22e-191	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MPHLCAIF_03292	9.55e-242	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MPHLCAIF_03293	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MPHLCAIF_03294	3.45e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MPHLCAIF_03295	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MPHLCAIF_03296	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MPHLCAIF_03297	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
MPHLCAIF_03298	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MPHLCAIF_03299	2.21e-150	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MPHLCAIF_03300	2.12e-87	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MPHLCAIF_03301	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
MPHLCAIF_03302	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
MPHLCAIF_03303	3.35e-146	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MPHLCAIF_03304	1.03e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MPHLCAIF_03307	1.11e-96	yckC	-	-	S	-	-	-	membrane
MPHLCAIF_03308	1.38e-66	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MPHLCAIF_03309	1.06e-57	-	-	-	K	-	-	-	MarR family
MPHLCAIF_03310	2.49e-27	-	-	-	-	-	-	-	-
MPHLCAIF_03311	2.13e-113	-	-	-	S	-	-	-	AAA domain
MPHLCAIF_03312	2.42e-27	-	-	-	S	-	-	-	AAA domain
MPHLCAIF_03313	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MPHLCAIF_03314	3.36e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MPHLCAIF_03315	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MPHLCAIF_03316	3.11e-73	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_03317	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_03318	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MPHLCAIF_03319	6.57e-136	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MPHLCAIF_03320	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
MPHLCAIF_03321	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MPHLCAIF_03326	4.39e-37	yddA	-	-	-	-	-	-	-
MPHLCAIF_03328	6.72e-60	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MPHLCAIF_03332	1.5e-81	-	-	-	S	-	-	-	Immunity protein 70
MPHLCAIF_03333	1.22e-249	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MPHLCAIF_03334	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MPHLCAIF_03335	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MPHLCAIF_03336	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MPHLCAIF_03337	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MPHLCAIF_03338	5.71e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MPHLCAIF_03339	5.09e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_03340	1.32e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_03341	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_03342	2.06e-69	-	-	-	-	-	-	-	-
MPHLCAIF_03343	3.95e-59	yhcC	-	-	-	-	-	-	-
MPHLCAIF_03344	1.4e-127	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MPHLCAIF_03345	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MPHLCAIF_03346	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MPHLCAIF_03347	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MPHLCAIF_03348	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MPHLCAIF_03349	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MPHLCAIF_03350	7.04e-104	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MPHLCAIF_03351	3.77e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MPHLCAIF_03352	5.64e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MPHLCAIF_03353	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MPHLCAIF_03354	9.27e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
MPHLCAIF_03355	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MPHLCAIF_03356	8.77e-144	yhzB	-	-	S	-	-	-	B3/4 domain
MPHLCAIF_03358	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_03359	3.81e-100	ygaO	-	-	-	-	-	-	-
MPHLCAIF_03360	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MPHLCAIF_03362	5.41e-275	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MPHLCAIF_03363	1.13e-187	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MPHLCAIF_03364	2.82e-216	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MPHLCAIF_03365	2.58e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MPHLCAIF_03366	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MPHLCAIF_03368	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MPHLCAIF_03369	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MPHLCAIF_03370	1.58e-36	-	-	-	-	-	-	-	-
MPHLCAIF_03371	1.23e-182	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
MPHLCAIF_03388	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
MPHLCAIF_03389	4.23e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
MPHLCAIF_03390	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MPHLCAIF_03391	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MPHLCAIF_03392	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MPHLCAIF_03393	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MPHLCAIF_03394	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MPHLCAIF_03395	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MPHLCAIF_03396	1.74e-222	ykuO	-	-	-	-	-	-	-
MPHLCAIF_03397	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
MPHLCAIF_03398	7.61e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03399	6.01e-99	ykuL	-	-	S	-	-	-	CBS domain
MPHLCAIF_03400	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MPHLCAIF_03401	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MPHLCAIF_03402	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03403	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MPHLCAIF_03404	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_03405	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MPHLCAIF_03406	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03407	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_03408	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
MPHLCAIF_03409	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MPHLCAIF_03410	1.05e-22	-	-	-	-	-	-	-	-
MPHLCAIF_03411	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MPHLCAIF_03412	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03413	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MPHLCAIF_03414	6.88e-84	-	-	-	S	-	-	-	HTH-like domain
MPHLCAIF_03415	0.0	-	-	-	L	-	-	-	AAA ATPase domain
MPHLCAIF_03416	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
MPHLCAIF_03417	0.0	-	-	-	V	-	-	-	Abi-like protein
MPHLCAIF_03418	2.64e-42	-	-	-	-	-	-	-	-
MPHLCAIF_03419	6.98e-279	-	-	-	L	-	-	-	Transposase
MPHLCAIF_03420	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
MPHLCAIF_03421	6.92e-17	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MPHLCAIF_03422	1.66e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
MPHLCAIF_03423	9.06e-47	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
MPHLCAIF_03424	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MPHLCAIF_03425	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MPHLCAIF_03426	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_03427	4.79e-160	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_03428	1.98e-23	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_03429	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MPHLCAIF_03430	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MPHLCAIF_03431	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MPHLCAIF_03432	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MPHLCAIF_03433	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MPHLCAIF_03434	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MPHLCAIF_03435	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
MPHLCAIF_03436	1.35e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MPHLCAIF_03437	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MPHLCAIF_03438	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MPHLCAIF_03439	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MPHLCAIF_03440	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_03441	2.49e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_03442	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MPHLCAIF_03443	7.7e-248	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
MPHLCAIF_03445	1.49e-207	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
MPHLCAIF_03446	4.82e-294	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MPHLCAIF_03448	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MPHLCAIF_03449	6.04e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MPHLCAIF_03450	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MPHLCAIF_03451	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MPHLCAIF_03452	6.15e-259	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MPHLCAIF_03453	1.18e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MPHLCAIF_03454	4.28e-149	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MPHLCAIF_03455	3.74e-37	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MPHLCAIF_03456	3.72e-202	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_03457	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
MPHLCAIF_03458	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MPHLCAIF_03459	6.46e-210	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MPHLCAIF_03460	4.64e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MPHLCAIF_03461	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MPHLCAIF_03462	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MPHLCAIF_03463	4.13e-78	yhjD	-	-	-	-	-	-	-
MPHLCAIF_03464	2.82e-140	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MPHLCAIF_03465	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MPHLCAIF_03466	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MPHLCAIF_03467	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_03470	3.5e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MPHLCAIF_03471	2.69e-255	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MPHLCAIF_03472	8.81e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
MPHLCAIF_03473	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MPHLCAIF_03474	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03475	4.83e-257	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MPHLCAIF_03476	3.19e-266	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MPHLCAIF_03477	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MPHLCAIF_03478	3.75e-30	-	-	-	-	-	-	-	-
MPHLCAIF_03479	1.74e-95	-	-	-	T	-	-	-	NACHT domain
MPHLCAIF_03480	4.46e-153	-	-	-	E	-	-	-	amino acid
MPHLCAIF_03481	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03482	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_03483	9.99e-59	-	-	-	-	-	-	-	-
MPHLCAIF_03484	1.35e-169	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MPHLCAIF_03485	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MPHLCAIF_03486	2.98e-53	-	-	-	-	-	-	-	-
MPHLCAIF_03490	3.49e-145	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
MPHLCAIF_03491	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MPHLCAIF_03492	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MPHLCAIF_03493	5.97e-174	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MPHLCAIF_03494	2.44e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
MPHLCAIF_03495	4.71e-83	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MPHLCAIF_03496	5.69e-105	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MPHLCAIF_03497	7.62e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MPHLCAIF_03498	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_03499	3.74e-24	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_03500	1.16e-234	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MPHLCAIF_03501	3.21e-70	ydeH	-	-	-	-	-	-	-
MPHLCAIF_03502	5.75e-135	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MPHLCAIF_03503	3.64e-142	-	-	-	-	-	-	-	-
MPHLCAIF_03504	2.51e-36	-	-	-	S	-	-	-	SNARE associated Golgi protein
MPHLCAIF_03505	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MPHLCAIF_03506	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MPHLCAIF_03507	9.01e-195	ydeK	-	-	EG	-	-	-	-transporter
MPHLCAIF_03508	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_03509	8.69e-96	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MPHLCAIF_03510	2.7e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MPHLCAIF_03511	4.66e-16	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MPHLCAIF_03512	1.32e-193	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MPHLCAIF_03513	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MPHLCAIF_03514	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MPHLCAIF_03515	8.66e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
MPHLCAIF_03516	9.99e-197	-	-	-	EG	-	-	-	EamA-like transporter family
MPHLCAIF_03517	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_03518	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
MPHLCAIF_03519	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MPHLCAIF_03520	1.5e-158	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MPHLCAIF_03521	1.12e-103	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MPHLCAIF_03523	3.75e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03524	1.55e-140	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_03525	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
MPHLCAIF_03526	2.2e-222	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MPHLCAIF_03527	7.6e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MPHLCAIF_03528	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MPHLCAIF_03529	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MPHLCAIF_03530	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MPHLCAIF_03531	4.51e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MPHLCAIF_03532	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MPHLCAIF_03533	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
MPHLCAIF_03534	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MPHLCAIF_03535	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MPHLCAIF_03536	1.74e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MPHLCAIF_03537	5.07e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MPHLCAIF_03538	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MPHLCAIF_03539	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MPHLCAIF_03540	4.16e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MPHLCAIF_03541	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MPHLCAIF_03542	9.06e-65	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MPHLCAIF_03543	5.64e-32	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MPHLCAIF_03544	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
MPHLCAIF_03545	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MPHLCAIF_03546	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MPHLCAIF_03547	5.2e-132	yjaV	-	-	-	-	-	-	-
MPHLCAIF_03548	3.04e-233	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MPHLCAIF_03549	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MPHLCAIF_03550	3.48e-33	yjzB	-	-	-	-	-	-	-
MPHLCAIF_03551	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MPHLCAIF_03552	5.08e-301	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MPHLCAIF_03553	3.86e-192	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MPHLCAIF_03554	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03555	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03556	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MPHLCAIF_03557	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03558	8.44e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03559	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MPHLCAIF_03560	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MPHLCAIF_03561	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MPHLCAIF_03562	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03563	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MPHLCAIF_03564	1.12e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03565	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MPHLCAIF_03566	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
MPHLCAIF_03567	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_03568	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MPHLCAIF_03569	4.1e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MPHLCAIF_03570	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MPHLCAIF_03571	9.9e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MPHLCAIF_03572	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MPHLCAIF_03573	2.68e-28	-	-	-	-	-	-	-	-
MPHLCAIF_03574	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MPHLCAIF_03575	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MPHLCAIF_03576	3.61e-122	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MPHLCAIF_03577	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03578	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MPHLCAIF_03579	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MPHLCAIF_03580	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MPHLCAIF_03581	3.01e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MPHLCAIF_03582	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MPHLCAIF_03583	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MPHLCAIF_03584	1.91e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MPHLCAIF_03585	4.49e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MPHLCAIF_03586	1.73e-272	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MPHLCAIF_03587	2.56e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MPHLCAIF_03588	1.86e-171	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MPHLCAIF_03589	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPHLCAIF_03590	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MPHLCAIF_03591	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MPHLCAIF_03592	2.09e-103	yjbX	-	-	S	-	-	-	Spore coat protein
MPHLCAIF_03593	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MPHLCAIF_03594	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MPHLCAIF_03595	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MPHLCAIF_03596	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
MPHLCAIF_03598	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MPHLCAIF_03601	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MPHLCAIF_03602	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MPHLCAIF_03603	6.31e-51	-	-	-	-	-	-	-	-
MPHLCAIF_03604	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_03605	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MPHLCAIF_03606	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MPHLCAIF_03607	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MPHLCAIF_03608	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MPHLCAIF_03609	6.86e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MPHLCAIF_03610	8.25e-271	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
MPHLCAIF_03612	1.71e-48	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MPHLCAIF_03613	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MPHLCAIF_03614	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MPHLCAIF_03616	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
MPHLCAIF_03617	5.33e-85	-	-	-	-	-	-	-	-
MPHLCAIF_03618	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MPHLCAIF_03619	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MPHLCAIF_03620	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
MPHLCAIF_03622	2.09e-103	-	-	-	-	-	-	-	-
MPHLCAIF_03623	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
MPHLCAIF_03624	3.26e-72	-	-	-	L	-	-	-	transposase activity
MPHLCAIF_03625	1.17e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MPHLCAIF_03626	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MPHLCAIF_03627	4.48e-35	ykzI	-	-	-	-	-	-	-
MPHLCAIF_03628	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MPHLCAIF_03629	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MPHLCAIF_03630	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MPHLCAIF_03631	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MPHLCAIF_03632	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MPHLCAIF_03633	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MPHLCAIF_03634	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MPHLCAIF_03635	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MPHLCAIF_03636	6.37e-86	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MPHLCAIF_03637	6.41e-52	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MPHLCAIF_03638	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MPHLCAIF_03639	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MPHLCAIF_03640	8.28e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MPHLCAIF_03641	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MPHLCAIF_03642	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MPHLCAIF_03643	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MPHLCAIF_03644	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MPHLCAIF_03645	8.84e-206	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MPHLCAIF_03646	4.22e-305	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MPHLCAIF_03647	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MPHLCAIF_03648	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MPHLCAIF_03649	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MPHLCAIF_03650	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MPHLCAIF_03651	3.74e-211	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MPHLCAIF_03652	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MPHLCAIF_03653	5.43e-52	ykoA	-	-	-	-	-	-	-
MPHLCAIF_03654	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MPHLCAIF_03655	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MPHLCAIF_03656	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MPHLCAIF_03657	1.75e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_03658	5.51e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MPHLCAIF_03659	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_03660	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MPHLCAIF_03661	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
MPHLCAIF_03662	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_03663	1.25e-95	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_03664	5.2e-260	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_03665	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MPHLCAIF_03666	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MPHLCAIF_03667	8.11e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MPHLCAIF_03668	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MPHLCAIF_03669	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MPHLCAIF_03670	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MPHLCAIF_03671	9.46e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
MPHLCAIF_03672	7.47e-233	yaaC	-	-	S	-	-	-	YaaC-like Protein
MPHLCAIF_03673	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MPHLCAIF_03674	1.24e-314	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MPHLCAIF_03675	5.26e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MPHLCAIF_03676	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MPHLCAIF_03677	4.64e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MPHLCAIF_03679	2.15e-158	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MPHLCAIF_03680	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MPHLCAIF_03681	1.48e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MPHLCAIF_03682	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MPHLCAIF_03683	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MPHLCAIF_03684	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MPHLCAIF_03685	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MPHLCAIF_03686	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MPHLCAIF_03687	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MPHLCAIF_03688	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MPHLCAIF_03689	6.67e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MPHLCAIF_03690	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MPHLCAIF_03691	1.86e-163	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_03692	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MPHLCAIF_03693	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_03694	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MPHLCAIF_03695	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MPHLCAIF_03696	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_03697	1.39e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MPHLCAIF_03699	2.69e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03700	2.74e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MPHLCAIF_03701	3.99e-09	-	-	-	-	-	-	-	-
MPHLCAIF_03702	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MPHLCAIF_03703	2.76e-115	stoA	-	-	CO	-	-	-	thiol-disulfide
MPHLCAIF_03704	1.12e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MPHLCAIF_03705	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MPHLCAIF_03706	2.6e-39	-	-	-	-	-	-	-	-
MPHLCAIF_03707	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MPHLCAIF_03708	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MPHLCAIF_03709	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MPHLCAIF_03710	1.69e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MPHLCAIF_03711	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MPHLCAIF_03712	4.34e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MPHLCAIF_03713	1.94e-226	ykvI	-	-	S	-	-	-	membrane
MPHLCAIF_03714	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MPHLCAIF_03715	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MPHLCAIF_03716	1.51e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MPHLCAIF_03717	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MPHLCAIF_03718	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MPHLCAIF_03719	7.14e-75	eag	-	-	-	-	-	-	-
MPHLCAIF_03721	3.6e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MPHLCAIF_03722	1.02e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MPHLCAIF_03723	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MPHLCAIF_03724	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MPHLCAIF_03725	2.79e-294	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MPHLCAIF_03726	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MPHLCAIF_03727	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MPHLCAIF_03728	6.78e-291	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MPHLCAIF_03729	5.4e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MPHLCAIF_03731	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MPHLCAIF_03732	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03733	4.75e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MPHLCAIF_03734	4.83e-30	ykzE	-	-	-	-	-	-	-
MPHLCAIF_03736	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MPHLCAIF_03739	9.36e-65	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MPHLCAIF_03740	1.82e-181	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MPHLCAIF_03741	5.45e-112	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MPHLCAIF_03742	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
MPHLCAIF_03743	2.87e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MPHLCAIF_03744	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MPHLCAIF_03747	1.09e-173	yndL	-	-	S	-	-	-	Replication protein
MPHLCAIF_03748	3.11e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MPHLCAIF_03749	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MPHLCAIF_03750	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MPHLCAIF_03751	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MPHLCAIF_03752	5.4e-143	yneB	-	-	L	-	-	-	resolvase
MPHLCAIF_03753	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
MPHLCAIF_03754	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MPHLCAIF_03755	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MPHLCAIF_03756	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MPHLCAIF_03757	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MPHLCAIF_03758	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MPHLCAIF_03759	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MPHLCAIF_03760	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MPHLCAIF_03761	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MPHLCAIF_03762	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MPHLCAIF_03763	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MPHLCAIF_03764	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MPHLCAIF_03765	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MPHLCAIF_03766	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MPHLCAIF_03767	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
MPHLCAIF_03769	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MPHLCAIF_03770	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MPHLCAIF_03771	3.3e-71	yneQ	-	-	-	-	-	-	-
MPHLCAIF_03772	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MPHLCAIF_03773	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MPHLCAIF_03774	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MPHLCAIF_03775	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MPHLCAIF_03776	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MPHLCAIF_03777	1.82e-18	-	-	-	-	-	-	-	-
MPHLCAIF_03778	8.74e-75	ynfC	-	-	-	-	-	-	-
MPHLCAIF_03779	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MPHLCAIF_03780	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
MPHLCAIF_03782	2.36e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MPHLCAIF_03783	3.29e-308	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MPHLCAIF_03784	5.64e-35	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MPHLCAIF_03785	1.72e-103	yngA	-	-	S	-	-	-	membrane
MPHLCAIF_03786	4.54e-209	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MPHLCAIF_03787	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
MPHLCAIF_03788	1.23e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
MPHLCAIF_03789	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MPHLCAIF_03790	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MPHLCAIF_03791	1.12e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MPHLCAIF_03792	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MPHLCAIF_03793	2.81e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MPHLCAIF_03794	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MPHLCAIF_03795	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MPHLCAIF_03796	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MPHLCAIF_03797	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MPHLCAIF_03798	8.25e-199	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MPHLCAIF_03799	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MPHLCAIF_03800	8.82e-37	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
MPHLCAIF_03801	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MPHLCAIF_03802	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MPHLCAIF_03803	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MPHLCAIF_03804	9.8e-313	yoeA	-	-	V	-	-	-	MATE efflux family protein
MPHLCAIF_03805	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MPHLCAIF_03806	1.36e-37	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPHLCAIF_03807	2.02e-48	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MPHLCAIF_03808	4.84e-85	-	-	-	S	-	-	-	damaged DNA binding
MPHLCAIF_03809	2.34e-14	-	-	-	S	-	-	-	YolD-like protein
MPHLCAIF_03812	2.06e-125	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_03813	5.44e-124	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
MPHLCAIF_03814	5.49e-102	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MPHLCAIF_03815	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MPHLCAIF_03816	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MPHLCAIF_03817	2.8e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MPHLCAIF_03818	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
MPHLCAIF_03819	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MPHLCAIF_03820	1.18e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MPHLCAIF_03821	1.98e-178	-	-	-	J	-	-	-	FR47-like protein
MPHLCAIF_03822	7.27e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03823	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MPHLCAIF_03824	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MPHLCAIF_03825	2.76e-220	yobV	-	-	K	-	-	-	WYL domain
MPHLCAIF_03826	2.58e-121	yobW	-	-	-	-	-	-	-
MPHLCAIF_03827	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MPHLCAIF_03828	9.39e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MPHLCAIF_03829	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MPHLCAIF_03830	9.86e-88	-	-	-	-	-	-	-	-
MPHLCAIF_03831	8.68e-67	-	-	-	-	-	-	-	-
MPHLCAIF_03832	1.08e-121	yocC	-	-	-	-	-	-	-
MPHLCAIF_03833	3.72e-238	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MPHLCAIF_03834	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MPHLCAIF_03835	4.09e-251	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MPHLCAIF_03836	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MPHLCAIF_03838	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MPHLCAIF_03839	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MPHLCAIF_03840	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MPHLCAIF_03841	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
MPHLCAIF_03842	4.29e-70	yocL	-	-	-	-	-	-	-
MPHLCAIF_03843	3.93e-41	-	-	-	-	-	-	-	-
MPHLCAIF_03844	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MPHLCAIF_03845	2.94e-55	yozN	-	-	-	-	-	-	-
MPHLCAIF_03846	1.83e-49	yocN	-	-	-	-	-	-	-
MPHLCAIF_03847	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
MPHLCAIF_03848	1.91e-42	yozC	-	-	-	-	-	-	-
MPHLCAIF_03849	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MPHLCAIF_03850	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MPHLCAIF_03851	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MPHLCAIF_03852	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MPHLCAIF_03853	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MPHLCAIF_03854	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MPHLCAIF_03855	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MPHLCAIF_03856	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MPHLCAIF_03857	8.98e-206	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MPHLCAIF_03858	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MPHLCAIF_03859	1.07e-266	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MPHLCAIF_03860	3.79e-292	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MPHLCAIF_03861	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MPHLCAIF_03863	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MPHLCAIF_03864	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MPHLCAIF_03865	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MPHLCAIF_03866	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MPHLCAIF_03867	1.85e-58	-	-	-	-	-	-	-	-
MPHLCAIF_03868	1.64e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MPHLCAIF_03869	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MPHLCAIF_03870	5.59e-14	-	-	-	-	-	-	-	-
MPHLCAIF_03871	1.26e-168	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MPHLCAIF_03872	7.01e-96	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MPHLCAIF_03873	2.3e-83	iolK	-	-	S	-	-	-	tautomerase
MPHLCAIF_03874	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
MPHLCAIF_03875	6.44e-139	yodC	-	-	C	-	-	-	nitroreductase
MPHLCAIF_03878	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MPHLCAIF_03879	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MPHLCAIF_03880	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MPHLCAIF_03881	2e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MPHLCAIF_03882	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MPHLCAIF_03883	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MPHLCAIF_03884	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MPHLCAIF_03885	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MPHLCAIF_03886	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MPHLCAIF_03887	8.36e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MPHLCAIF_03888	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MPHLCAIF_03889	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MPHLCAIF_03890	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MPHLCAIF_03891	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MPHLCAIF_03893	1.17e-148	-	-	-	-	-	-	-	-
MPHLCAIF_03894	5.53e-175	-	-	-	-	-	-	-	-
MPHLCAIF_03895	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MPHLCAIF_03896	2.5e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MPHLCAIF_03897	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MPHLCAIF_03898	1.22e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MPHLCAIF_03899	3.64e-59	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MPHLCAIF_03900	8.87e-76	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MPHLCAIF_03901	1.42e-225	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MPHLCAIF_03902	1.48e-172	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MPHLCAIF_03903	5.98e-202	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MPHLCAIF_03904	1.53e-245	-	-	-	S	-	-	-	Ion transport 2 domain protein
MPHLCAIF_03905	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_03906	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MPHLCAIF_03907	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
MPHLCAIF_03908	1.62e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MPHLCAIF_03909	2.23e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
MPHLCAIF_03910	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
MPHLCAIF_03911	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
MPHLCAIF_03912	8.03e-81	ymzB	-	-	-	-	-	-	-
MPHLCAIF_03913	1.04e-204	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MPHLCAIF_03914	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MPHLCAIF_03916	8e-163	ymaC	-	-	S	-	-	-	Replication protein
MPHLCAIF_03917	6.98e-104	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MPHLCAIF_03918	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
MPHLCAIF_03919	1.21e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MPHLCAIF_03921	3.13e-75	ymaF	-	-	S	-	-	-	YmaF family
MPHLCAIF_03922	5.61e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MPHLCAIF_03923	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MPHLCAIF_03924	1.63e-31	-	-	-	-	-	-	-	-
MPHLCAIF_03925	1.2e-30	ymzA	-	-	-	-	-	-	-
MPHLCAIF_03926	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MPHLCAIF_03927	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MPHLCAIF_03928	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MPHLCAIF_03929	2.24e-141	-	-	-	-	-	-	-	-
MPHLCAIF_03930	1.16e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_03931	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MPHLCAIF_03932	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MPHLCAIF_03933	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MPHLCAIF_03934	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MPHLCAIF_03935	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MPHLCAIF_03936	4.35e-171	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MPHLCAIF_03937	1.4e-59	-	-	-	CE	-	-	-	IrrE N-terminal-like domain
MPHLCAIF_03938	3.93e-09	-	-	-	K	-	-	-	Helix-turn-helix
MPHLCAIF_03940	7.74e-65	-	-	-	S	-	-	-	Phage antirepressor protein KilAC domain
MPHLCAIF_03941	4.75e-28	-	-	-	-	-	-	-	-
MPHLCAIF_03943	3.42e-26	-	-	-	S	-	-	-	Uncharacterized protein YqaH
MPHLCAIF_03945	5.36e-120	-	-	-	S	-	-	-	DNA protection
MPHLCAIF_03946	6.48e-216	-	-	-	S	-	-	-	AAA domain
MPHLCAIF_03947	1.15e-07	-	-	-	-	-	-	-	-
MPHLCAIF_03948	3.5e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MPHLCAIF_03949	0.0	-	-	-	S	-	-	-	hydrolase activity
MPHLCAIF_03950	3.9e-85	-	-	-	-	-	-	-	-
MPHLCAIF_03951	3.14e-121	-	-	-	S	-	-	-	nuclease activity
MPHLCAIF_03952	1.06e-106	-	-	-	-	-	-	-	-
MPHLCAIF_03954	2.62e-78	-	-	-	-	-	-	-	-
MPHLCAIF_03958	1.34e-77	-	-	-	L	-	-	-	Terminase, small subunit
MPHLCAIF_03959	0.0	terL	-	-	S	-	-	-	Terminase
MPHLCAIF_03961	3.12e-215	-	-	-	S	-	-	-	portal protein
MPHLCAIF_03962	3.96e-94	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MPHLCAIF_03963	1.64e-161	-	-	-	S	-	-	-	capsid protein
MPHLCAIF_03964	5.45e-13	-	-	-	-	-	-	-	-
MPHLCAIF_03966	8.17e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
MPHLCAIF_03967	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MPHLCAIF_03969	1.46e-33	-	-	-	-	-	-	-	-
MPHLCAIF_03972	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
MPHLCAIF_03974	1.22e-136	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
MPHLCAIF_03975	7.54e-92	-	-	-	L	-	-	-	Prophage endopeptidase tail
MPHLCAIF_03976	1.37e-67	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
MPHLCAIF_03977	9.06e-135	-	-	-	D	-	-	-	phage tail tape measure protein
MPHLCAIF_03979	7.39e-33	-	-	-	-	-	-	-	-
MPHLCAIF_03980	1.56e-65	-	-	-	N	-	-	-	domain, Protein
MPHLCAIF_03981	7.61e-40	-	-	-	-	-	-	-	-
MPHLCAIF_03982	4.04e-22	-	-	-	-	-	-	-	-
MPHLCAIF_03983	2.82e-34	-	-	-	-	-	-	-	-
MPHLCAIF_03985	1.74e-102	-	-	-	-	-	-	-	-
MPHLCAIF_03986	4.51e-08	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MPHLCAIF_03987	2.45e-106	-	-	-	S	-	-	-	Phage minor capsid protein 2
MPHLCAIF_03988	1.27e-192	-	-	-	-	-	-	-	-
MPHLCAIF_03989	7.57e-31	-	-	-	S	-	-	-	Helix-turn-helix of insertion element transposase
MPHLCAIF_03990	5.35e-169	-	-	-	S	-	-	-	TIGRFAM Phage uncharacterised protein, C-terminal
MPHLCAIF_03991	1.12e-86	-	-	-	L	-	-	-	Phage integrase family
MPHLCAIF_03992	3.04e-11	-	-	-	-	-	-	-	-
MPHLCAIF_03995	2.14e-51	-	-	-	-	-	-	-	-
MPHLCAIF_03998	4.34e-30	-	-	-	K	-	-	-	Sigma-70, region 4
MPHLCAIF_04006	0.0	-	-	-	V	-	-	-	Beta-lactamase
MPHLCAIF_04008	3.11e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MPHLCAIF_04010	4.82e-69	ynaF	-	-	-	-	-	-	-
MPHLCAIF_04011	1.4e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MPHLCAIF_04019	9.5e-51	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MPHLCAIF_04020	0.0	-	-	-	-	-	-	-	-
MPHLCAIF_04021	1.62e-307	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
MPHLCAIF_04022	1.96e-141	-	-	-	S	-	-	-	Phage tail protein
MPHLCAIF_04023	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
MPHLCAIF_04024	4.09e-16	-	-	-	-	-	-	-	-
MPHLCAIF_04025	1.58e-36	-	-	-	-	-	-	-	-
MPHLCAIF_04026	9.75e-79	-	-	-	-	-	-	-	-
MPHLCAIF_04027	1.42e-40	-	-	-	-	-	-	-	-
MPHLCAIF_04028	1.54e-62	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MPHLCAIF_04029	1.23e-32	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MPHLCAIF_04030	1.23e-39	-	-	-	S	-	-	-	peptidoglycan catabolic process
MPHLCAIF_04031	8.02e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
MPHLCAIF_04032	3.43e-227	-	-	-	S	-	-	-	capsid protein
MPHLCAIF_04033	9.36e-135	-	-	-	S	-	-	-	peptidase activity
MPHLCAIF_04034	4.77e-273	-	-	-	S	-	-	-	Phage portal protein
MPHLCAIF_04035	2.58e-14	-	-	-	-	-	-	-	-
MPHLCAIF_04036	1.37e-277	-	-	-	S	-	-	-	Phage Terminase
MPHLCAIF_04037	1e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
MPHLCAIF_04038	2.63e-11	-	-	-	-	-	-	-	-
MPHLCAIF_04039	5.3e-47	-	-	-	-	-	-	-	-
MPHLCAIF_04040	1.46e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MPHLCAIF_04041	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MPHLCAIF_04042	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MPHLCAIF_04043	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MPHLCAIF_04044	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
MPHLCAIF_04045	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MPHLCAIF_04046	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MPHLCAIF_04047	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MPHLCAIF_04048	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MPHLCAIF_04049	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MPHLCAIF_04050	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MPHLCAIF_04051	5.44e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MPHLCAIF_04052	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MPHLCAIF_04053	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MPHLCAIF_04054	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MPHLCAIF_04055	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MPHLCAIF_04056	4.11e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MPHLCAIF_04057	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
MPHLCAIF_04058	1.51e-174	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
MPHLCAIF_04059	1.59e-65	-	-	-	L	-	-	-	Transposase
MPHLCAIF_04060	5.01e-131	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MPHLCAIF_04061	1.87e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MPHLCAIF_04062	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MPHLCAIF_04063	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
MPHLCAIF_04064	3.5e-35	-	-	-	K	-	-	-	Helix-turn-helix domain
MPHLCAIF_04065	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
MPHLCAIF_04066	1.27e-07	-	-	-	S	-	-	-	peptidoglycan catabolic process
MPHLCAIF_04072	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MPHLCAIF_04073	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MPHLCAIF_04074	1.8e-87	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MPHLCAIF_04075	1.53e-220	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MPHLCAIF_04076	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MPHLCAIF_04077	1.47e-100	-	-	-	K	-	-	-	acetyltransferase
MPHLCAIF_04078	2.94e-261	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MPHLCAIF_04079	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
MPHLCAIF_04080	2.28e-84	yhfM	-	-	-	-	-	-	-
MPHLCAIF_04081	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MPHLCAIF_04082	2.13e-143	yhfK	-	-	GM	-	-	-	NmrA-like family
MPHLCAIF_04083	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MPHLCAIF_04084	9.84e-182	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MPHLCAIF_04085	2.76e-288	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MPHLCAIF_04086	1.79e-92	-	-	-	S	-	-	-	ASCH
MPHLCAIF_04087	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
MPHLCAIF_04088	2.67e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
MPHLCAIF_04089	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MPHLCAIF_04090	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MPHLCAIF_04091	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_04092	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MPHLCAIF_04093	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MPHLCAIF_04094	6.13e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MPHLCAIF_04095	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MPHLCAIF_04096	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MPHLCAIF_04097	1e-44	-	-	-	C	-	-	-	Rubrerythrin
MPHLCAIF_04098	5.44e-312	yhfA	-	-	C	-	-	-	membrane
MPHLCAIF_04099	8.54e-289	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MPHLCAIF_04100	9.67e-160	ecsC	-	-	S	-	-	-	EcsC protein family
MPHLCAIF_04101	4.23e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MPHLCAIF_04102	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MPHLCAIF_04103	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MPHLCAIF_04104	7.5e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MPHLCAIF_04105	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MPHLCAIF_04106	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
MPHLCAIF_04107	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MPHLCAIF_04108	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MPHLCAIF_04109	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MPHLCAIF_04110	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MPHLCAIF_04111	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MPHLCAIF_04112	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MPHLCAIF_04113	0.0	yhaN	-	-	L	-	-	-	AAA domain
MPHLCAIF_04114	9.44e-301	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MPHLCAIF_04115	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MPHLCAIF_04116	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MPHLCAIF_04117	1.89e-35	-	-	-	S	-	-	-	YhzD-like protein
MPHLCAIF_04118	1.45e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MPHLCAIF_04120	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MPHLCAIF_04121	4.36e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MPHLCAIF_04122	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MPHLCAIF_04123	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MPHLCAIF_04124	3.3e-92	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MPHLCAIF_04125	2.11e-131	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
MPHLCAIF_04126	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MPHLCAIF_04127	1.19e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MPHLCAIF_04128	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MPHLCAIF_04129	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MPHLCAIF_04130	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MPHLCAIF_04132	4.44e-38	bhlA	-	-	S	-	-	-	BhlA holin family
MPHLCAIF_04133	3.19e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
MPHLCAIF_04134	4.08e-162	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MPHLCAIF_04135	3.25e-72	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
MPHLCAIF_04136	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MPHLCAIF_04137	6.2e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4917)
MPHLCAIF_04138	3.12e-09	-	-	-	-	-	-	-	-
MPHLCAIF_04139	1.68e-13	-	-	-	-	-	-	-	-
MPHLCAIF_04141	1.46e-105	-	-	-	-	-	-	-	-
MPHLCAIF_04142	4.13e-51	-	-	-	-	-	-	-	-
MPHLCAIF_04143	4.13e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
MPHLCAIF_04144	9.3e-51	ynaC	-	-	-	-	-	-	-
MPHLCAIF_04145	3.65e-81	ynaC	-	-	-	-	-	-	-
MPHLCAIF_04146	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
MPHLCAIF_04147	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MPHLCAIF_04148	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_04149	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MPHLCAIF_04150	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
MPHLCAIF_04151	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MPHLCAIF_04152	2.6e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MPHLCAIF_04153	5.03e-194	nodB1	-	-	G	-	-	-	deacetylase
MPHLCAIF_04154	8.05e-178	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MPHLCAIF_04155	3.04e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MPHLCAIF_04156	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MPHLCAIF_04157	9.03e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MPHLCAIF_04158	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MPHLCAIF_04159	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MPHLCAIF_04160	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MPHLCAIF_04161	3.62e-171	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MPHLCAIF_04162	3.35e-92	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MPHLCAIF_04163	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MPHLCAIF_04164	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MPHLCAIF_04165	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MPHLCAIF_04166	2.74e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
MPHLCAIF_04167	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MPHLCAIF_04168	2.05e-256	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MPHLCAIF_04169	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MPHLCAIF_04170	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MPHLCAIF_04171	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MPHLCAIF_04172	2.89e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MPHLCAIF_04173	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MPHLCAIF_04174	3.72e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MPHLCAIF_04175	1.45e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MPHLCAIF_04176	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_04177	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MPHLCAIF_04179	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MPHLCAIF_04180	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MPHLCAIF_04181	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MPHLCAIF_04182	8.79e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MPHLCAIF_04184	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MPHLCAIF_04185	9.03e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
MPHLCAIF_04186	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
MPHLCAIF_04187	9.97e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MPHLCAIF_04188	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MPHLCAIF_04189	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MPHLCAIF_04190	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MPHLCAIF_04191	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MPHLCAIF_04192	6.51e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MPHLCAIF_04194	8.38e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MPHLCAIF_04196	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MPHLCAIF_04197	7.18e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MPHLCAIF_04198	1.11e-41	-	-	-	-	-	-	-	-
MPHLCAIF_04199	3.54e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MPHLCAIF_04200	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MPHLCAIF_04201	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MPHLCAIF_04202	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MPHLCAIF_04203	1.26e-20	yjlB	-	-	S	-	-	-	Cupin domain
MPHLCAIF_04204	1.16e-55	yjlB	-	-	S	-	-	-	Cupin domain
MPHLCAIF_04205	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MPHLCAIF_04206	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MPHLCAIF_04207	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MPHLCAIF_04208	1.81e-315	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
MPHLCAIF_04209	8.48e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MPHLCAIF_04210	3.22e-246	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MPHLCAIF_04211	1.6e-272	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MPHLCAIF_04212	5.47e-196	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_04213	1.37e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
MPHLCAIF_04214	8.11e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MPHLCAIF_04215	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MPHLCAIF_04216	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MPHLCAIF_04217	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MPHLCAIF_04218	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
MPHLCAIF_04219	8.62e-269	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MPHLCAIF_04220	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
MPHLCAIF_04221	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MPHLCAIF_04222	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MPHLCAIF_04224	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MPHLCAIF_04225	7.54e-22	-	-	-	-	-	-	-	-
MPHLCAIF_04228	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MPHLCAIF_04230	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
MPHLCAIF_04233	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
MPHLCAIF_04234	8.92e-96	-	-	-	-	-	-	-	-
MPHLCAIF_04237	0.00063	-	-	-	L	-	-	-	Pfam:DUF955
MPHLCAIF_04241	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MPHLCAIF_04242	2.17e-38	-	-	-	-	-	-	-	-
MPHLCAIF_04244	1.78e-73	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MPHLCAIF_04245	4.9e-36	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
MPHLCAIF_04246	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MPHLCAIF_04247	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MPHLCAIF_04248	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MPHLCAIF_04249	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MPHLCAIF_04250	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MPHLCAIF_04251	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
MPHLCAIF_04252	8.04e-111	yycN	-	-	K	-	-	-	Acetyltransferase
MPHLCAIF_04253	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MPHLCAIF_04254	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MPHLCAIF_04255	5.94e-118	-	-	-	S	-	-	-	DinB family
MPHLCAIF_04256	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_04257	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MPHLCAIF_04258	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
MPHLCAIF_04259	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MPHLCAIF_04260	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MPHLCAIF_04261	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MPHLCAIF_04262	1.24e-156	ydhC	-	-	K	-	-	-	FCD
MPHLCAIF_04263	5.08e-300	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MPHLCAIF_04264	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MPHLCAIF_04265	4.28e-163	-	-	-	-	-	-	-	-
MPHLCAIF_04266	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MPHLCAIF_04267	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MPHLCAIF_04269	3.12e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MPHLCAIF_04270	5.22e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MPHLCAIF_04271	5.93e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MPHLCAIF_04272	3.64e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MPHLCAIF_04273	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_04274	2.31e-41	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MPHLCAIF_04275	1.22e-173	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MPHLCAIF_04276	1.2e-114	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MPHLCAIF_04277	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MPHLCAIF_04278	2.22e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MPHLCAIF_04279	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MPHLCAIF_04280	1.07e-09	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MPHLCAIF_04281	1.24e-76	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MPHLCAIF_04282	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MPHLCAIF_04283	9.18e-172	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MPHLCAIF_04286	1.16e-311	-	-	-	-	-	-	-	-
MPHLCAIF_04297	3.99e-53	-	-	-	-	-	-	-	-
MPHLCAIF_04299	1.07e-57	-	-	-	S	-	-	-	transposition, DNA-mediated
MPHLCAIF_04300	1.82e-28	-	-	-	S	-	-	-	HTH-like domain
MPHLCAIF_04301	6.28e-61	-	-	-	L	-	-	-	Phage integrase family
MPHLCAIF_04302	0.000711	-	-	-	-	-	-	-	-
MPHLCAIF_04305	7.11e-181	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
MPHLCAIF_04306	1.56e-128	-	-	-	-	-	-	-	-
MPHLCAIF_04307	2.82e-235	yddH	-	-	M	-	-	-	Lysozyme-like
MPHLCAIF_04308	1.11e-111	yddI	-	-	-	-	-	-	-
MPHLCAIF_04309	5.28e-83	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
MPHLCAIF_04310	4.67e-90	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MPHLCAIF_04313	1.34e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MPHLCAIF_04315	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MPHLCAIF_04316	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MPHLCAIF_04317	1.39e-15	-	-	-	-	-	-	-	-
MPHLCAIF_04318	4.48e-22	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MPHLCAIF_04319	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MPHLCAIF_04320	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
MPHLCAIF_04330	1.14e-124	-	-	-	L	-	-	-	Integrase
MPHLCAIF_04331	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MPHLCAIF_04332	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MPHLCAIF_04333	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_04334	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MPHLCAIF_04335	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MPHLCAIF_04336	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MPHLCAIF_04337	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MPHLCAIF_04338	5.87e-173	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MPHLCAIF_04339	3.43e-100	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MPHLCAIF_04340	1.07e-54	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MPHLCAIF_04341	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MPHLCAIF_04342	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MPHLCAIF_04343	8.07e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MPHLCAIF_04344	7.05e-172	yoxB	-	-	-	-	-	-	-
MPHLCAIF_04345	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MPHLCAIF_04346	6.24e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_04347	2.92e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MPHLCAIF_04348	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MPHLCAIF_04349	8.15e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MPHLCAIF_04350	1.24e-299	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MPHLCAIF_04351	1.07e-25	-	-	-	-	-	-	-	-
MPHLCAIF_04352	4.09e-128	yddE	-	-	S	-	-	-	AAA-like domain
MPHLCAIF_04353	2.21e-242	yddE	-	-	S	-	-	-	AAA-like domain
MPHLCAIF_04354	1.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
MPHLCAIF_04355	0.0	yddE	-	-	S	-	-	-	AAA-like domain
MPHLCAIF_04356	3.29e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)