ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IOCDEKDB_00001 6.98e-279 - - - L - - - Transposase
IOCDEKDB_00002 4.78e-152 - - - L - - - Bacterial dnaA protein
IOCDEKDB_00004 5.08e-26 xkdM - - S - - - Phage tail tube protein
IOCDEKDB_00005 2.43e-14 - - - - - - - -
IOCDEKDB_00008 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
IOCDEKDB_00011 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
IOCDEKDB_00012 1.4e-264 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00013 8.79e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IOCDEKDB_00014 6.17e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IOCDEKDB_00015 2.45e-23 - - - S - - - YrzO-like protein
IOCDEKDB_00016 3.17e-212 yrdR - - EG - - - EamA-like transporter family
IOCDEKDB_00017 1.4e-203 - - - K - - - Transcriptional regulator
IOCDEKDB_00018 5e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IOCDEKDB_00019 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IOCDEKDB_00021 9.63e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IOCDEKDB_00022 2.79e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
IOCDEKDB_00023 2.1e-117 azlC - - E - - - AzlC protein
IOCDEKDB_00024 4.45e-99 bkdR - - K - - - helix_turn_helix ASNC type
IOCDEKDB_00025 3.92e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IOCDEKDB_00026 1.16e-284 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IOCDEKDB_00028 7.38e-131 yrdC - - Q - - - Isochorismatase family
IOCDEKDB_00029 1.09e-73 - - - S - - - Protein of unknown function (DUF2568)
IOCDEKDB_00031 2.01e-118 yrdA - - S - - - DinB family
IOCDEKDB_00032 1.48e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
IOCDEKDB_00033 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IOCDEKDB_00034 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IOCDEKDB_00035 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
IOCDEKDB_00037 6.26e-168 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IOCDEKDB_00038 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_00039 5.72e-238 yrpG - - C - - - Aldo/keto reductase family
IOCDEKDB_00040 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IOCDEKDB_00041 8.42e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_00042 1.05e-178 - - - S - - - Alpha beta hydrolase
IOCDEKDB_00043 6.61e-80 - - - T - - - sh3 domain protein
IOCDEKDB_00044 1.05e-81 - - - T - - - sh3 domain protein
IOCDEKDB_00045 1.1e-85 - - - E - - - Glyoxalase-like domain
IOCDEKDB_00046 4.04e-48 yraG - - - ko:K06440 - ko00000 -
IOCDEKDB_00047 9.61e-84 yraF - - M - - - Spore coat protein
IOCDEKDB_00048 3.71e-283 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOCDEKDB_00049 6.11e-36 yraE - - - ko:K06440 - ko00000 -
IOCDEKDB_00050 4.9e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
IOCDEKDB_00051 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IOCDEKDB_00052 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
IOCDEKDB_00053 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IOCDEKDB_00054 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IOCDEKDB_00055 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IOCDEKDB_00056 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IOCDEKDB_00057 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IOCDEKDB_00058 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
IOCDEKDB_00059 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
IOCDEKDB_00060 0.0 levR - - K - - - PTS system fructose IIA component
IOCDEKDB_00061 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_00062 5.63e-137 yrhP - - E - - - LysE type translocator
IOCDEKDB_00063 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
IOCDEKDB_00064 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_00065 2.88e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
IOCDEKDB_00066 2.18e-84 oatA - - I - - - Acyltransferase family
IOCDEKDB_00067 3.76e-287 oatA - - I - - - Acyltransferase family
IOCDEKDB_00068 6.32e-59 yrhK - - S - - - YrhK-like protein
IOCDEKDB_00069 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IOCDEKDB_00070 2.35e-201 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IOCDEKDB_00071 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IOCDEKDB_00072 4.3e-124 yrhH - - Q - - - methyltransferase
IOCDEKDB_00073 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IOCDEKDB_00074 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IOCDEKDB_00075 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IOCDEKDB_00076 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IOCDEKDB_00077 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
IOCDEKDB_00099 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IOCDEKDB_00100 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IOCDEKDB_00101 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
IOCDEKDB_00102 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
IOCDEKDB_00103 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IOCDEKDB_00104 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IOCDEKDB_00105 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
IOCDEKDB_00106 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
IOCDEKDB_00107 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
IOCDEKDB_00109 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
IOCDEKDB_00110 7.97e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
IOCDEKDB_00111 6.8e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOCDEKDB_00112 2.32e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
IOCDEKDB_00113 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
IOCDEKDB_00114 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IOCDEKDB_00115 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IOCDEKDB_00116 4.49e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IOCDEKDB_00117 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IOCDEKDB_00118 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IOCDEKDB_00119 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOCDEKDB_00120 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IOCDEKDB_00121 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOCDEKDB_00122 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOCDEKDB_00123 7.59e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IOCDEKDB_00124 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IOCDEKDB_00125 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IOCDEKDB_00126 3e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IOCDEKDB_00127 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IOCDEKDB_00128 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IOCDEKDB_00129 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOCDEKDB_00130 6.79e-95 ytkA - - S - - - YtkA-like
IOCDEKDB_00132 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IOCDEKDB_00133 1.59e-81 ytkC - - S - - - Bacteriophage holin family
IOCDEKDB_00134 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IOCDEKDB_00135 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOCDEKDB_00136 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IOCDEKDB_00137 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IOCDEKDB_00138 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IOCDEKDB_00139 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IOCDEKDB_00140 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IOCDEKDB_00141 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOCDEKDB_00142 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IOCDEKDB_00143 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_00144 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IOCDEKDB_00145 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IOCDEKDB_00146 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IOCDEKDB_00147 2.75e-136 ytqB - - J - - - Putative rRNA methylase
IOCDEKDB_00148 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IOCDEKDB_00149 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
IOCDEKDB_00151 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IOCDEKDB_00152 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00153 4.66e-213 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_00154 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IOCDEKDB_00155 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00156 2.69e-294 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IOCDEKDB_00157 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_00158 1.3e-238 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IOCDEKDB_00159 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00160 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IOCDEKDB_00161 5.75e-78 yttA - - S - - - Pfam Transposase IS66
IOCDEKDB_00162 4.05e-267 yttB - - EGP - - - Major facilitator superfamily
IOCDEKDB_00163 1.49e-180 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IOCDEKDB_00164 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
IOCDEKDB_00165 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IOCDEKDB_00166 1.22e-68 ytwF - - P - - - Sulfurtransferase
IOCDEKDB_00167 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IOCDEKDB_00168 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IOCDEKDB_00169 1.77e-198 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_00170 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IOCDEKDB_00171 2.08e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_00172 1.67e-221 - - - S - - - Acetyl xylan esterase (AXE1)
IOCDEKDB_00173 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IOCDEKDB_00174 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IOCDEKDB_00175 2.83e-256 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOCDEKDB_00176 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IOCDEKDB_00177 1.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IOCDEKDB_00178 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IOCDEKDB_00179 1.05e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
IOCDEKDB_00180 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IOCDEKDB_00181 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IOCDEKDB_00182 5.52e-276 ytdP - - K - - - Transcriptional regulator
IOCDEKDB_00183 1.36e-202 ytdP - - K - - - Transcriptional regulator
IOCDEKDB_00184 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IOCDEKDB_00185 4.8e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IOCDEKDB_00186 2.27e-92 yteS - - G - - - transport
IOCDEKDB_00187 1.83e-251 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
IOCDEKDB_00188 9.57e-98 yteU - - S - - - Integral membrane protein
IOCDEKDB_00189 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IOCDEKDB_00190 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IOCDEKDB_00191 1.16e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IOCDEKDB_00192 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_00193 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IOCDEKDB_00194 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IOCDEKDB_00195 4.65e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IOCDEKDB_00196 2.89e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IOCDEKDB_00197 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IOCDEKDB_00198 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IOCDEKDB_00199 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IOCDEKDB_00200 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IOCDEKDB_00201 4.92e-212 ytlQ - - - - - - -
IOCDEKDB_00202 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IOCDEKDB_00203 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
IOCDEKDB_00204 3.02e-192 ytmP - - M - - - Phosphotransferase
IOCDEKDB_00205 9.51e-61 ytzH - - S - - - YtzH-like protein
IOCDEKDB_00206 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOCDEKDB_00207 3.18e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IOCDEKDB_00208 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IOCDEKDB_00209 6.75e-67 ytzB - - S - - - small secreted protein
IOCDEKDB_00210 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IOCDEKDB_00211 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IOCDEKDB_00212 3.17e-75 ytpP - - CO - - - Thioredoxin
IOCDEKDB_00213 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
IOCDEKDB_00214 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOCDEKDB_00215 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IOCDEKDB_00216 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IOCDEKDB_00217 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOCDEKDB_00218 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IOCDEKDB_00219 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
IOCDEKDB_00220 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IOCDEKDB_00221 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IOCDEKDB_00222 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IOCDEKDB_00223 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IOCDEKDB_00224 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IOCDEKDB_00225 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IOCDEKDB_00226 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IOCDEKDB_00227 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOCDEKDB_00228 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOCDEKDB_00230 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOCDEKDB_00231 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IOCDEKDB_00232 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IOCDEKDB_00233 9.83e-141 yttP - - K - - - Transcriptional regulator
IOCDEKDB_00234 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IOCDEKDB_00235 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOCDEKDB_00236 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IOCDEKDB_00237 2.74e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IOCDEKDB_00238 8.89e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOCDEKDB_00239 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IOCDEKDB_00240 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IOCDEKDB_00241 0.0 ytcJ - - S - - - amidohydrolase
IOCDEKDB_00242 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOCDEKDB_00243 4.62e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IOCDEKDB_00244 2.36e-111 yteJ - - S - - - RDD family
IOCDEKDB_00245 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
IOCDEKDB_00246 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
IOCDEKDB_00247 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOCDEKDB_00248 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IOCDEKDB_00249 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOCDEKDB_00250 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IOCDEKDB_00251 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOCDEKDB_00252 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IOCDEKDB_00254 3.28e-181 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_00255 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
IOCDEKDB_00256 3.29e-73 - - - S - - - Domain of unknown function (DUF1874)
IOCDEKDB_00257 0.0 yddE - - S - - - AAA-like domain
IOCDEKDB_00258 1.7e-118 yddD - - S - - - TcpE family
IOCDEKDB_00259 9.78e-54 yddC - - - - - - -
IOCDEKDB_00260 1.29e-223 yddB - - S - - - Conjugative transposon protein TcpC
IOCDEKDB_00261 2.49e-63 yddA - - - - - - -
IOCDEKDB_00264 2.68e-23 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
IOCDEKDB_00265 2.58e-254 nicK - - L ko:K07467 - ko00000 Replication initiation factor
IOCDEKDB_00266 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
IOCDEKDB_00267 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
IOCDEKDB_00269 1.35e-55 - - - - - - - -
IOCDEKDB_00270 8.96e-24 - - - - - - - -
IOCDEKDB_00271 1.91e-81 - - - K - - - Transcriptional
IOCDEKDB_00272 1.65e-118 - - - E - - - IrrE N-terminal-like domain
IOCDEKDB_00273 5.14e-269 ydcL - - L - - - Belongs to the 'phage' integrase family
IOCDEKDB_00281 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IOCDEKDB_00282 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IOCDEKDB_00283 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_00284 4.42e-105 ydcG - - S - - - EVE domain
IOCDEKDB_00287 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IOCDEKDB_00288 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_00289 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IOCDEKDB_00290 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IOCDEKDB_00291 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IOCDEKDB_00292 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IOCDEKDB_00293 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IOCDEKDB_00294 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IOCDEKDB_00295 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IOCDEKDB_00296 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IOCDEKDB_00297 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOCDEKDB_00298 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IOCDEKDB_00299 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOCDEKDB_00300 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IOCDEKDB_00301 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IOCDEKDB_00302 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IOCDEKDB_00303 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOCDEKDB_00304 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOCDEKDB_00305 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IOCDEKDB_00306 4.19e-75 ydbP - - CO - - - Thioredoxin
IOCDEKDB_00307 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOCDEKDB_00308 2.1e-11 - - - S - - - Fur-regulated basic protein A
IOCDEKDB_00309 1.49e-26 - - - S - - - Fur-regulated basic protein B
IOCDEKDB_00310 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
IOCDEKDB_00311 9.32e-70 ydbL - - - - - - -
IOCDEKDB_00312 4.95e-158 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOCDEKDB_00313 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00314 5.38e-230 ydbI - - S - - - AI-2E family transporter
IOCDEKDB_00315 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOCDEKDB_00316 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IOCDEKDB_00317 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IOCDEKDB_00318 6.07e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IOCDEKDB_00319 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
IOCDEKDB_00320 3.66e-82 ydbC - - S - - - Domain of unknown function (DUF4937
IOCDEKDB_00321 2.17e-78 ydbB - - G - - - Cupin domain
IOCDEKDB_00322 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
IOCDEKDB_00323 4.3e-190 ydbA - - P - - - EcsC protein family
IOCDEKDB_00324 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IOCDEKDB_00325 1.67e-42 ydaS - - S - - - membrane
IOCDEKDB_00326 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IOCDEKDB_00327 6.14e-53 - - - - - - - -
IOCDEKDB_00329 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
IOCDEKDB_00330 1.84e-34 - - - - - - - -
IOCDEKDB_00332 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IOCDEKDB_00333 8.17e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IOCDEKDB_00334 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOCDEKDB_00335 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IOCDEKDB_00336 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IOCDEKDB_00337 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IOCDEKDB_00338 6.13e-100 ydaG - - S - - - general stress protein
IOCDEKDB_00339 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOCDEKDB_00340 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IOCDEKDB_00341 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_00342 1e-127 ydaC - - Q - - - Methyltransferase domain
IOCDEKDB_00343 0.0 ydaB - - IQ - - - acyl-CoA ligase
IOCDEKDB_00344 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IOCDEKDB_00345 3.5e-219 ycsN - - S - - - Oxidoreductase
IOCDEKDB_00346 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IOCDEKDB_00347 8.97e-65 yczJ - - S - - - biosynthesis
IOCDEKDB_00349 1.2e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IOCDEKDB_00350 1.55e-170 kipR - - K - - - Transcriptional regulator
IOCDEKDB_00351 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IOCDEKDB_00352 2.8e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IOCDEKDB_00353 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IOCDEKDB_00354 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IOCDEKDB_00355 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IOCDEKDB_00356 3.15e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IOCDEKDB_00358 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IOCDEKDB_00359 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
IOCDEKDB_00360 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IOCDEKDB_00362 3.39e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
IOCDEKDB_00363 3.1e-268 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IOCDEKDB_00364 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IOCDEKDB_00365 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IOCDEKDB_00366 1.34e-74 - - - - - - - -
IOCDEKDB_00367 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IOCDEKDB_00368 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IOCDEKDB_00369 1.34e-132 ycnI - - S - - - protein conserved in bacteria
IOCDEKDB_00370 1.39e-185 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_00371 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IOCDEKDB_00372 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOCDEKDB_00373 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOCDEKDB_00374 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_00375 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IOCDEKDB_00376 1.68e-60 ycnE - - S - - - Monooxygenase
IOCDEKDB_00377 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IOCDEKDB_00378 5.87e-198 ycnC - - K - - - Transcriptional regulator
IOCDEKDB_00379 0.0 ycnB - - EGP - - - the major facilitator superfamily
IOCDEKDB_00380 1.18e-96 - - - V - - - Restriction endonuclease
IOCDEKDB_00381 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IOCDEKDB_00382 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00383 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_00384 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_00385 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IOCDEKDB_00386 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IOCDEKDB_00388 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IOCDEKDB_00389 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IOCDEKDB_00390 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_00391 5.33e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IOCDEKDB_00392 1.38e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IOCDEKDB_00393 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IOCDEKDB_00394 8.22e-288 gerKC - - S ko:K06297 - ko00000 spore germination
IOCDEKDB_00395 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IOCDEKDB_00397 0.0 yclG - - M - - - Pectate lyase superfamily protein
IOCDEKDB_00398 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IOCDEKDB_00399 1.84e-200 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
IOCDEKDB_00400 6.45e-55 yclD - - - - - - -
IOCDEKDB_00401 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IOCDEKDB_00402 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IOCDEKDB_00403 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IOCDEKDB_00404 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IOCDEKDB_00405 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IOCDEKDB_00406 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IOCDEKDB_00407 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IOCDEKDB_00408 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
IOCDEKDB_00409 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IOCDEKDB_00410 2.81e-316 ycxD - - K - - - GntR family transcriptional regulator
IOCDEKDB_00411 3.27e-205 ycxC - - EG - - - EamA-like transporter family
IOCDEKDB_00412 8.93e-124 - - - S - - - YcxB-like protein
IOCDEKDB_00413 5.99e-286 - - - EGP - - - Major Facilitator Superfamily
IOCDEKDB_00414 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IOCDEKDB_00415 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IOCDEKDB_00416 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_00417 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_00418 6.05e-86 hxlR - - K - - - transcriptional
IOCDEKDB_00419 6.57e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IOCDEKDB_00420 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IOCDEKDB_00421 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_00422 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_00423 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
IOCDEKDB_00424 3.36e-91 nin - - S - - - Competence protein J (ComJ)
IOCDEKDB_00425 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IOCDEKDB_00426 2.42e-27 - - - S - - - AAA domain
IOCDEKDB_00427 2.13e-113 - - - S - - - AAA domain
IOCDEKDB_00428 2.49e-27 - - - - - - - -
IOCDEKDB_00429 1.06e-57 - - - K - - - MarR family
IOCDEKDB_00430 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
IOCDEKDB_00431 1.11e-96 yckC - - S - - - membrane
IOCDEKDB_00434 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IOCDEKDB_00435 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IOCDEKDB_00436 2.26e-123 yciC - - S - - - GTPases (G3E family)
IOCDEKDB_00437 2.72e-141 yciC - - S - - - GTPases (G3E family)
IOCDEKDB_00438 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
IOCDEKDB_00439 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
IOCDEKDB_00440 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IOCDEKDB_00441 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IOCDEKDB_00442 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOCDEKDB_00443 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IOCDEKDB_00444 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IOCDEKDB_00445 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IOCDEKDB_00446 9.55e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IOCDEKDB_00447 7.22e-191 ycgS - - I - - - alpha/beta hydrolase fold
IOCDEKDB_00448 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
IOCDEKDB_00449 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
IOCDEKDB_00450 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IOCDEKDB_00451 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOCDEKDB_00452 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOCDEKDB_00453 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IOCDEKDB_00454 1.29e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IOCDEKDB_00455 7.75e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IOCDEKDB_00456 8.95e-225 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
IOCDEKDB_00457 4.85e-182 - - - Q - - - ubiE/COQ5 methyltransferase family
IOCDEKDB_00458 7.55e-59 orfX1 - - L - - - Transposase
IOCDEKDB_00459 7.33e-144 - - - L - - - Integrase core domain
IOCDEKDB_00460 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IOCDEKDB_00462 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOCDEKDB_00463 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
IOCDEKDB_00464 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
IOCDEKDB_00465 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOCDEKDB_00467 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IOCDEKDB_00468 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
IOCDEKDB_00469 1.13e-29 yjfB - - S - - - Putative motility protein
IOCDEKDB_00470 9.97e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IOCDEKDB_00471 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
IOCDEKDB_00472 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
IOCDEKDB_00473 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IOCDEKDB_00474 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
IOCDEKDB_00475 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
IOCDEKDB_00477 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IOCDEKDB_00479 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IOCDEKDB_00480 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOCDEKDB_00481 1.11e-41 - - - - - - - -
IOCDEKDB_00482 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IOCDEKDB_00483 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IOCDEKDB_00484 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IOCDEKDB_00485 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IOCDEKDB_00486 1.26e-20 yjlB - - S - - - Cupin domain
IOCDEKDB_00487 1.16e-55 yjlB - - S - - - Cupin domain
IOCDEKDB_00488 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IOCDEKDB_00489 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IOCDEKDB_00490 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IOCDEKDB_00491 1.81e-315 - - - G ko:K03292 - ko00000 symporter YjmB
IOCDEKDB_00492 8.48e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
IOCDEKDB_00493 3.22e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IOCDEKDB_00494 1.6e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IOCDEKDB_00495 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_00496 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
IOCDEKDB_00497 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IOCDEKDB_00498 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IOCDEKDB_00499 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IOCDEKDB_00500 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IOCDEKDB_00501 2.71e-103 yjoA - - S - - - DinB family
IOCDEKDB_00502 8.62e-269 VCP - - O - - - AAA domain (dynein-related subfamily)
IOCDEKDB_00503 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IOCDEKDB_00505 5.36e-203 ybaS - - S - - - Na -dependent transporter
IOCDEKDB_00506 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
IOCDEKDB_00507 3.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_00508 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_00509 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IOCDEKDB_00510 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IOCDEKDB_00511 2.33e-302 ybbC - - S - - - protein conserved in bacteria
IOCDEKDB_00512 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IOCDEKDB_00513 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IOCDEKDB_00514 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_00515 2.4e-190 ybbH - - K - - - transcriptional
IOCDEKDB_00516 1.92e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IOCDEKDB_00517 3.13e-114 ybbJ - - J - - - acetyltransferase
IOCDEKDB_00518 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
IOCDEKDB_00524 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_00525 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IOCDEKDB_00526 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOCDEKDB_00527 1.6e-287 ybbR - - S - - - protein conserved in bacteria
IOCDEKDB_00528 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOCDEKDB_00529 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOCDEKDB_00530 5.87e-54 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOCDEKDB_00531 9.34e-128 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOCDEKDB_00532 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IOCDEKDB_00533 1.29e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOCDEKDB_00534 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOCDEKDB_00535 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
IOCDEKDB_00536 9.45e-121 ybcF - - P - - - carbonic anhydrase
IOCDEKDB_00538 1.6e-63 - - - - - - - -
IOCDEKDB_00539 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
IOCDEKDB_00540 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
IOCDEKDB_00541 2.78e-219 - - - T - - - His Kinase A (phospho-acceptor) domain
IOCDEKDB_00543 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
IOCDEKDB_00544 1.49e-192 ybdN - - - - - - -
IOCDEKDB_00545 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
IOCDEKDB_00546 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_00547 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IOCDEKDB_00548 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
IOCDEKDB_00549 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
IOCDEKDB_00550 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IOCDEKDB_00551 1.28e-37 ybyB - - - - - - -
IOCDEKDB_00552 0.0 ybeC - - E - - - amino acid
IOCDEKDB_00553 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IOCDEKDB_00554 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IOCDEKDB_00555 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
IOCDEKDB_00556 8.65e-202 ybfA - - K - - - FR47-like protein
IOCDEKDB_00557 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00558 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00561 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IOCDEKDB_00562 1.06e-207 ybfH - - EG - - - EamA-like transporter family
IOCDEKDB_00563 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
IOCDEKDB_00564 3.63e-43 - - - K - - - sigma factor activity
IOCDEKDB_00565 2.73e-28 xhlB - - S - - - SPP1 phage holin
IOCDEKDB_00566 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOCDEKDB_00567 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOCDEKDB_00568 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
IOCDEKDB_00569 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOCDEKDB_00570 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IOCDEKDB_00571 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOCDEKDB_00572 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOCDEKDB_00573 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOCDEKDB_00574 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOCDEKDB_00575 2.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IOCDEKDB_00576 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOCDEKDB_00577 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOCDEKDB_00578 2.9e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IOCDEKDB_00579 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IOCDEKDB_00580 3.77e-97 - - - S - - - Bacterial PH domain
IOCDEKDB_00581 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IOCDEKDB_00582 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IOCDEKDB_00583 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
IOCDEKDB_00584 5.34e-227 yyaD - - S - - - Membrane
IOCDEKDB_00585 7.41e-45 yyzM - - S - - - protein conserved in bacteria
IOCDEKDB_00586 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOCDEKDB_00587 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOCDEKDB_00588 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IOCDEKDB_00589 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOCDEKDB_00590 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOCDEKDB_00591 1.15e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IOCDEKDB_00592 5.01e-78 ccpB - - K - - - Transcriptional regulator
IOCDEKDB_00593 3.58e-50 - - - EGP - - - PFAM Major Facilitator Superfamily
IOCDEKDB_00594 1.15e-30 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
IOCDEKDB_00595 8.75e-26 - - - H - - - ThiF family
IOCDEKDB_00596 3.43e-81 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_00597 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
IOCDEKDB_00598 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IOCDEKDB_00599 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IOCDEKDB_00600 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
IOCDEKDB_00601 2.59e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IOCDEKDB_00602 8.28e-135 yyaP - - H - - - RibD C-terminal domain
IOCDEKDB_00603 1.5e-85 - - - S - - - YjbR
IOCDEKDB_00604 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IOCDEKDB_00605 1.01e-123 yyaS - - S ko:K07149 - ko00000 Membrane
IOCDEKDB_00606 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
IOCDEKDB_00607 4.54e-100 yybA - - K - - - transcriptional
IOCDEKDB_00608 2.04e-88 - - - S - - - Metallo-beta-lactamase superfamily
IOCDEKDB_00609 6.02e-127 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00610 2.81e-162 yybG - - S - - - Pentapeptide repeat-containing protein
IOCDEKDB_00611 2.39e-85 - - - S - - - SnoaL-like domain
IOCDEKDB_00612 2.05e-183 - - - - - - - -
IOCDEKDB_00613 9.88e-141 - - - K - - - TipAS antibiotic-recognition domain
IOCDEKDB_00614 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00616 1.11e-90 - - - - - - - -
IOCDEKDB_00617 1.4e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IOCDEKDB_00618 1.3e-87 yybR - - K - - - Transcriptional regulator
IOCDEKDB_00619 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
IOCDEKDB_00620 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
IOCDEKDB_00622 1.5e-204 yybS - - S - - - membrane
IOCDEKDB_00623 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IOCDEKDB_00624 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IOCDEKDB_00625 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOCDEKDB_00626 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IOCDEKDB_00627 1.89e-22 yycC - - K - - - YycC-like protein
IOCDEKDB_00629 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IOCDEKDB_00630 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IOCDEKDB_00631 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_00632 1.75e-312 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOCDEKDB_00637 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_00638 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_00639 0.0 yycH - - S - - - protein conserved in bacteria
IOCDEKDB_00640 3.44e-200 yycI - - S - - - protein conserved in bacteria
IOCDEKDB_00641 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IOCDEKDB_00642 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOCDEKDB_00643 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IOCDEKDB_00644 2.31e-54 sdpR - - K - - - transcriptional
IOCDEKDB_00645 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IOCDEKDB_00646 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
IOCDEKDB_00647 4.85e-119 - - - - - - - -
IOCDEKDB_00648 5.82e-20 - - - - - - - -
IOCDEKDB_00649 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IOCDEKDB_00650 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IOCDEKDB_00651 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IOCDEKDB_00653 8.7e-239 - - - S - - - aspartate phosphatase
IOCDEKDB_00654 3.04e-110 yycN - - K - - - Acetyltransferase
IOCDEKDB_00655 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IOCDEKDB_00656 4.42e-254 yycP - - - - - - -
IOCDEKDB_00657 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
IOCDEKDB_00659 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IOCDEKDB_00660 9.49e-89 - - - - - - - -
IOCDEKDB_00662 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOCDEKDB_00664 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
IOCDEKDB_00665 2.96e-245 yceH - - P - - - Belongs to the TelA family
IOCDEKDB_00666 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IOCDEKDB_00667 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IOCDEKDB_00668 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IOCDEKDB_00669 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IOCDEKDB_00670 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IOCDEKDB_00671 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOCDEKDB_00672 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOCDEKDB_00673 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IOCDEKDB_00674 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IOCDEKDB_00675 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IOCDEKDB_00676 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IOCDEKDB_00677 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IOCDEKDB_00678 2.93e-45 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_00679 4.37e-182 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_00680 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IOCDEKDB_00681 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_00682 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_00683 3.53e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
IOCDEKDB_00684 3.94e-221 yccK - - C - - - Aldo keto reductase
IOCDEKDB_00685 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_00686 2.86e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IOCDEKDB_00687 1.42e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
IOCDEKDB_00688 1.62e-161 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
IOCDEKDB_00689 1.77e-43 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IOCDEKDB_00690 4.03e-156 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
IOCDEKDB_00691 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
IOCDEKDB_00692 4.32e-78 - - - S - - - RDD family
IOCDEKDB_00693 5.69e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOCDEKDB_00694 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IOCDEKDB_00695 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IOCDEKDB_00696 4.75e-307 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IOCDEKDB_00697 4.66e-257 ycbU - - E - - - Selenocysteine lyase
IOCDEKDB_00698 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IOCDEKDB_00699 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOCDEKDB_00700 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOCDEKDB_00701 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IOCDEKDB_00702 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
IOCDEKDB_00703 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IOCDEKDB_00704 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
IOCDEKDB_00705 1.73e-149 - - - S - - - ABC-2 family transporter protein
IOCDEKDB_00706 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_00707 4.37e-214 ycbM - - T - - - Histidine kinase
IOCDEKDB_00708 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_00709 4.05e-215 eamA1 - - EG - - - spore germination
IOCDEKDB_00710 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IOCDEKDB_00711 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IOCDEKDB_00712 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IOCDEKDB_00713 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
IOCDEKDB_00714 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IOCDEKDB_00715 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00716 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOCDEKDB_00717 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
IOCDEKDB_00718 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IOCDEKDB_00719 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_00720 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IOCDEKDB_00721 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IOCDEKDB_00722 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IOCDEKDB_00723 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IOCDEKDB_00724 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IOCDEKDB_00725 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IOCDEKDB_00727 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IOCDEKDB_00728 1.01e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOCDEKDB_00729 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_00730 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOCDEKDB_00731 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IOCDEKDB_00732 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_00733 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
IOCDEKDB_00734 2.25e-59 ybfN - - - - - - -
IOCDEKDB_00735 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IOCDEKDB_00736 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
IOCDEKDB_00737 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOCDEKDB_00738 1.31e-212 - - - S - - - Alpha/beta hydrolase family
IOCDEKDB_00740 1.69e-228 mpr - - M - - - Belongs to the peptidase S1B family
IOCDEKDB_00741 4.6e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOCDEKDB_00742 2.61e-73 - - - - - - - -
IOCDEKDB_00743 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IOCDEKDB_00744 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IOCDEKDB_00745 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IOCDEKDB_00746 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IOCDEKDB_00747 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IOCDEKDB_00748 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IOCDEKDB_00749 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IOCDEKDB_00750 2.46e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IOCDEKDB_00751 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IOCDEKDB_00752 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOCDEKDB_00753 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IOCDEKDB_00754 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
IOCDEKDB_00755 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
IOCDEKDB_00756 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
IOCDEKDB_00757 5.18e-81 yqhP - - - - - - -
IOCDEKDB_00758 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IOCDEKDB_00759 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IOCDEKDB_00760 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IOCDEKDB_00761 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IOCDEKDB_00762 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOCDEKDB_00763 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IOCDEKDB_00764 2.72e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IOCDEKDB_00765 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOCDEKDB_00766 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IOCDEKDB_00767 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IOCDEKDB_00768 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IOCDEKDB_00769 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IOCDEKDB_00770 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IOCDEKDB_00771 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
IOCDEKDB_00772 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
IOCDEKDB_00773 2.84e-36 yqzE - - S - - - YqzE-like protein
IOCDEKDB_00774 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IOCDEKDB_00775 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IOCDEKDB_00776 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IOCDEKDB_00777 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
IOCDEKDB_00778 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IOCDEKDB_00779 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IOCDEKDB_00780 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IOCDEKDB_00781 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
IOCDEKDB_00782 8.73e-233 yqxL - - P - - - Mg2 transporter protein
IOCDEKDB_00783 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IOCDEKDB_00784 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOCDEKDB_00786 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IOCDEKDB_00787 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IOCDEKDB_00788 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IOCDEKDB_00789 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
IOCDEKDB_00790 7.34e-66 yqgV - - S - - - Thiamine-binding protein
IOCDEKDB_00791 2.69e-256 yqgU - - - - - - -
IOCDEKDB_00792 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IOCDEKDB_00793 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IOCDEKDB_00794 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IOCDEKDB_00795 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
IOCDEKDB_00796 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
IOCDEKDB_00797 3.38e-14 yqgO - - - - - - -
IOCDEKDB_00798 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOCDEKDB_00799 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IOCDEKDB_00800 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
IOCDEKDB_00802 2.81e-67 yqzD - - - - - - -
IOCDEKDB_00803 1.09e-93 yqzC - - S - - - YceG-like family
IOCDEKDB_00804 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOCDEKDB_00805 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOCDEKDB_00806 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IOCDEKDB_00807 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IOCDEKDB_00808 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IOCDEKDB_00809 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IOCDEKDB_00810 1.09e-290 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IOCDEKDB_00811 1.31e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IOCDEKDB_00812 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IOCDEKDB_00813 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
IOCDEKDB_00814 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
IOCDEKDB_00815 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IOCDEKDB_00816 2.38e-80 yqfX - - S - - - membrane
IOCDEKDB_00817 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IOCDEKDB_00818 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IOCDEKDB_00819 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IOCDEKDB_00820 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IOCDEKDB_00821 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IOCDEKDB_00822 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOCDEKDB_00823 3.73e-46 yqfQ - - S - - - YqfQ-like protein
IOCDEKDB_00824 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IOCDEKDB_00825 4.21e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOCDEKDB_00826 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IOCDEKDB_00827 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IOCDEKDB_00828 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOCDEKDB_00829 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOCDEKDB_00830 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IOCDEKDB_00831 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IOCDEKDB_00832 3.29e-144 ccpN - - K - - - CBS domain
IOCDEKDB_00833 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IOCDEKDB_00834 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IOCDEKDB_00835 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IOCDEKDB_00836 5.29e-27 - - - S - - - YqzL-like protein
IOCDEKDB_00837 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOCDEKDB_00838 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IOCDEKDB_00839 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IOCDEKDB_00840 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOCDEKDB_00841 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IOCDEKDB_00843 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IOCDEKDB_00844 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IOCDEKDB_00845 2.07e-60 yqfC - - S - - - sporulation protein YqfC
IOCDEKDB_00846 2.23e-56 yqfB - - - - - - -
IOCDEKDB_00847 4.35e-192 yqfA - - S - - - UPF0365 protein
IOCDEKDB_00848 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IOCDEKDB_00849 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IOCDEKDB_00850 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IOCDEKDB_00851 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IOCDEKDB_00852 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IOCDEKDB_00853 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOCDEKDB_00854 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IOCDEKDB_00855 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOCDEKDB_00856 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IOCDEKDB_00857 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOCDEKDB_00858 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOCDEKDB_00859 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IOCDEKDB_00860 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOCDEKDB_00861 2.28e-66 yqxA - - S - - - Protein of unknown function (DUF3679)
IOCDEKDB_00862 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IOCDEKDB_00863 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IOCDEKDB_00864 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IOCDEKDB_00865 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IOCDEKDB_00866 2.36e-22 - - - S - - - YqzM-like protein
IOCDEKDB_00867 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IOCDEKDB_00868 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IOCDEKDB_00869 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IOCDEKDB_00870 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCDEKDB_00871 5.44e-176 yqeM - - Q - - - Methyltransferase
IOCDEKDB_00872 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOCDEKDB_00873 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IOCDEKDB_00874 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOCDEKDB_00875 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IOCDEKDB_00876 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IOCDEKDB_00877 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IOCDEKDB_00878 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IOCDEKDB_00880 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IOCDEKDB_00881 1.44e-177 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_00882 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
IOCDEKDB_00883 2.98e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
IOCDEKDB_00884 7.4e-168 - - - - - - - -
IOCDEKDB_00885 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
IOCDEKDB_00886 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_00887 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOCDEKDB_00888 1.14e-197 yybE - - K - - - Transcriptional regulator
IOCDEKDB_00889 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
IOCDEKDB_00891 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
IOCDEKDB_00892 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOCDEKDB_00893 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
IOCDEKDB_00894 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
IOCDEKDB_00896 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
IOCDEKDB_00897 1.1e-20 - - - S - - - SMI1 / KNR4 family
IOCDEKDB_00898 5.24e-60 - - - - - - - -
IOCDEKDB_00903 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
IOCDEKDB_00904 1.89e-40 - - - - - - - -
IOCDEKDB_00905 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOCDEKDB_00906 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IOCDEKDB_00907 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
IOCDEKDB_00908 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IOCDEKDB_00909 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IOCDEKDB_00911 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IOCDEKDB_00912 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOCDEKDB_00913 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IOCDEKDB_00914 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOCDEKDB_00915 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IOCDEKDB_00916 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOCDEKDB_00917 3.57e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IOCDEKDB_00918 5.41e-311 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
IOCDEKDB_00919 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IOCDEKDB_00920 1.05e-255 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IOCDEKDB_00921 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_00922 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
IOCDEKDB_00923 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IOCDEKDB_00924 9.23e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOCDEKDB_00925 2.29e-29 ywtC - - - - - - -
IOCDEKDB_00926 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IOCDEKDB_00927 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IOCDEKDB_00928 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IOCDEKDB_00929 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
IOCDEKDB_00930 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOCDEKDB_00931 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOCDEKDB_00932 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IOCDEKDB_00933 1.59e-201 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IOCDEKDB_00934 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IOCDEKDB_00935 3.97e-119 batE - - T - - - Sh3 type 3 domain protein
IOCDEKDB_00936 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
IOCDEKDB_00937 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IOCDEKDB_00938 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IOCDEKDB_00939 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IOCDEKDB_00940 1.37e-217 alsR - - K - - - LysR substrate binding domain
IOCDEKDB_00941 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOCDEKDB_00942 4.33e-162 ywrJ - - - - - - -
IOCDEKDB_00943 7.86e-162 cotB - - - ko:K06325 - ko00000 -
IOCDEKDB_00944 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
IOCDEKDB_00945 1.4e-17 - - - - - - - -
IOCDEKDB_00946 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IOCDEKDB_00947 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
IOCDEKDB_00948 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IOCDEKDB_00949 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IOCDEKDB_00950 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IOCDEKDB_00951 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IOCDEKDB_00953 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
IOCDEKDB_00954 4.73e-209 - - - K - - - Transcriptional regulator
IOCDEKDB_00955 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IOCDEKDB_00957 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
IOCDEKDB_00958 4.93e-95 ywqJ - - S - - - Pre-toxin TG
IOCDEKDB_00959 1.3e-23 - - - - - - - -
IOCDEKDB_00960 2.5e-26 - - - - - - - -
IOCDEKDB_00961 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
IOCDEKDB_00962 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
IOCDEKDB_00964 1.45e-108 ywqG - - S - - - Domain of unknown function (DUF1963)
IOCDEKDB_00965 1.3e-38 ywqG - - S - - - Domain of unknown function (DUF1963)
IOCDEKDB_00966 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOCDEKDB_00967 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IOCDEKDB_00968 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IOCDEKDB_00969 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IOCDEKDB_00970 3.6e-25 - - - - - - - -
IOCDEKDB_00971 0.0 ywqB - - S - - - SWIM zinc finger
IOCDEKDB_00972 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IOCDEKDB_00973 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IOCDEKDB_00974 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IOCDEKDB_00975 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IOCDEKDB_00976 2.79e-40 ywpG - - - - - - -
IOCDEKDB_00977 3.59e-88 ywpF - - S - - - YwpF-like protein
IOCDEKDB_00978 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
IOCDEKDB_00979 4.66e-186 ywpD - - T - - - Histidine kinase
IOCDEKDB_00980 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOCDEKDB_00981 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOCDEKDB_00982 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IOCDEKDB_00983 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IOCDEKDB_00984 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IOCDEKDB_00985 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IOCDEKDB_00986 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IOCDEKDB_00987 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
IOCDEKDB_00988 3.21e-268 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_00989 1.14e-309 ywoF - - P - - - Right handed beta helix region
IOCDEKDB_00990 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IOCDEKDB_00991 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
IOCDEKDB_00992 3e-133 yjgF - - Q - - - Isochorismatase family
IOCDEKDB_00993 7.16e-101 - - - - - - - -
IOCDEKDB_00994 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IOCDEKDB_00995 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IOCDEKDB_00996 1.72e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IOCDEKDB_00997 9.05e-93 ywnJ - - S - - - VanZ like family
IOCDEKDB_00998 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IOCDEKDB_00999 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IOCDEKDB_01000 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
IOCDEKDB_01001 6.7e-234 - - - M - - - NeuB family
IOCDEKDB_01002 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
IOCDEKDB_01003 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOCDEKDB_01004 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IOCDEKDB_01005 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
IOCDEKDB_01006 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IOCDEKDB_01007 4.58e-85 ywnA - - K - - - Transcriptional regulator
IOCDEKDB_01008 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IOCDEKDB_01009 6.46e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IOCDEKDB_01010 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IOCDEKDB_01011 2.15e-19 csbD - - K - - - CsbD-like
IOCDEKDB_01012 3.22e-109 ywmF - - S - - - Peptidase M50
IOCDEKDB_01013 2.18e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_01014 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOCDEKDB_01015 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IOCDEKDB_01017 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IOCDEKDB_01018 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IOCDEKDB_01019 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IOCDEKDB_01020 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOCDEKDB_01021 6.59e-172 ywmB - - S - - - TATA-box binding
IOCDEKDB_01022 4.54e-45 ywzB - - S - - - membrane
IOCDEKDB_01023 2.92e-113 ywmA - - - - - - -
IOCDEKDB_01024 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IOCDEKDB_01025 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOCDEKDB_01026 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOCDEKDB_01027 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOCDEKDB_01028 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOCDEKDB_01029 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOCDEKDB_01030 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOCDEKDB_01031 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IOCDEKDB_01032 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IOCDEKDB_01033 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOCDEKDB_01034 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOCDEKDB_01035 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
IOCDEKDB_01036 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IOCDEKDB_01037 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOCDEKDB_01038 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
IOCDEKDB_01039 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOCDEKDB_01040 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IOCDEKDB_01041 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IOCDEKDB_01042 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IOCDEKDB_01044 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOCDEKDB_01045 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOCDEKDB_01046 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_01047 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IOCDEKDB_01048 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IOCDEKDB_01049 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IOCDEKDB_01050 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IOCDEKDB_01051 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IOCDEKDB_01052 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IOCDEKDB_01053 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IOCDEKDB_01054 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOCDEKDB_01056 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IOCDEKDB_01057 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IOCDEKDB_01058 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IOCDEKDB_01059 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
IOCDEKDB_01060 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOCDEKDB_01061 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOCDEKDB_01062 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
IOCDEKDB_01063 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IOCDEKDB_01064 5.54e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IOCDEKDB_01065 1.4e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IOCDEKDB_01066 5.49e-124 ywjB - - H - - - RibD C-terminal domain
IOCDEKDB_01067 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IOCDEKDB_01068 9.8e-37 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IOCDEKDB_01069 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOCDEKDB_01070 8.39e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IOCDEKDB_01071 2.77e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IOCDEKDB_01072 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IOCDEKDB_01073 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOCDEKDB_01074 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IOCDEKDB_01075 1.84e-179 ywiC - - S - - - YwiC-like protein
IOCDEKDB_01076 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IOCDEKDB_01077 8.44e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IOCDEKDB_01078 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IOCDEKDB_01079 5.42e-95 ywiB - - S - - - protein conserved in bacteria
IOCDEKDB_01080 3.71e-12 - - - S - - - Bacteriocin subtilosin A
IOCDEKDB_01081 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
IOCDEKDB_01083 6.11e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IOCDEKDB_01084 1.09e-293 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
IOCDEKDB_01085 4.01e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
IOCDEKDB_01086 7.39e-312 - - - L - - - Peptidase, M16
IOCDEKDB_01088 1.18e-315 ywhL - - CO - - - amine dehydrogenase activity
IOCDEKDB_01089 4.48e-273 ywhK - - CO - - - amine dehydrogenase activity
IOCDEKDB_01090 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IOCDEKDB_01092 2.03e-84 - - - S - - - Aminoacyl-tRNA editing domain
IOCDEKDB_01093 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IOCDEKDB_01094 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IOCDEKDB_01095 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IOCDEKDB_01096 2.1e-64 - - - - - - - -
IOCDEKDB_01097 1.92e-123 ywhD - - S - - - YwhD family
IOCDEKDB_01098 3.29e-154 ywhC - - S - - - Peptidase family M50
IOCDEKDB_01099 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IOCDEKDB_01100 1.45e-93 ywhA - - K - - - Transcriptional regulator
IOCDEKDB_01101 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOCDEKDB_01103 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
IOCDEKDB_01104 1.1e-103 yffB - - K - - - Transcriptional regulator
IOCDEKDB_01105 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
IOCDEKDB_01106 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IOCDEKDB_01107 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IOCDEKDB_01108 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IOCDEKDB_01109 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
IOCDEKDB_01110 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IOCDEKDB_01111 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_01112 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IOCDEKDB_01113 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IOCDEKDB_01114 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IOCDEKDB_01115 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IOCDEKDB_01116 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IOCDEKDB_01117 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IOCDEKDB_01118 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_01119 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IOCDEKDB_01120 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IOCDEKDB_01121 3.81e-275 ywfA - - EGP - - - -transporter
IOCDEKDB_01122 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IOCDEKDB_01123 0.0 rocB - - E - - - arginine degradation protein
IOCDEKDB_01124 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IOCDEKDB_01125 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IOCDEKDB_01126 2.14e-100 - - - - - - - -
IOCDEKDB_01127 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IOCDEKDB_01128 1.92e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOCDEKDB_01129 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOCDEKDB_01130 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOCDEKDB_01131 5.73e-240 spsG - - M - - - Spore Coat
IOCDEKDB_01132 1.09e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
IOCDEKDB_01133 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IOCDEKDB_01134 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IOCDEKDB_01135 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IOCDEKDB_01136 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IOCDEKDB_01137 7.76e-185 spsA - - M - - - Spore Coat
IOCDEKDB_01138 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IOCDEKDB_01139 1.59e-78 ywdK - - S - - - small membrane protein
IOCDEKDB_01140 3.75e-303 ywdJ - - F - - - Xanthine uracil
IOCDEKDB_01141 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
IOCDEKDB_01142 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IOCDEKDB_01143 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOCDEKDB_01144 5.46e-191 ywdF - - S - - - Glycosyltransferase like family 2
IOCDEKDB_01145 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IOCDEKDB_01146 6.19e-39 ywdA - - - - - - -
IOCDEKDB_01147 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IOCDEKDB_01148 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_01149 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
IOCDEKDB_01150 6.46e-112 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IOCDEKDB_01151 5e-63 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IOCDEKDB_01153 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IOCDEKDB_01154 2.83e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOCDEKDB_01155 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IOCDEKDB_01156 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IOCDEKDB_01157 3.69e-260 - - - S - - - Acetyltransferase
IOCDEKDB_01158 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IOCDEKDB_01159 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IOCDEKDB_01160 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IOCDEKDB_01161 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOCDEKDB_01162 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IOCDEKDB_01163 5.11e-49 ydaS - - S - - - membrane
IOCDEKDB_01164 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IOCDEKDB_01165 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOCDEKDB_01166 3.33e-77 gtcA - - S - - - GtrA-like protein
IOCDEKDB_01167 1.98e-157 ywcC - - K - - - transcriptional regulator
IOCDEKDB_01169 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
IOCDEKDB_01170 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOCDEKDB_01171 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IOCDEKDB_01172 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IOCDEKDB_01173 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
IOCDEKDB_01174 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
IOCDEKDB_01175 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOCDEKDB_01176 1.54e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOCDEKDB_01177 1.28e-201 ywbI - - K - - - Transcriptional regulator
IOCDEKDB_01178 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IOCDEKDB_01179 1.21e-143 ywbG - - M - - - effector of murein hydrolase
IOCDEKDB_01180 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
IOCDEKDB_01181 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IOCDEKDB_01182 1.9e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IOCDEKDB_01183 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IOCDEKDB_01184 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
IOCDEKDB_01185 1.05e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOCDEKDB_01186 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IOCDEKDB_01187 2.67e-308 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_01188 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IOCDEKDB_01189 1.54e-215 gspA - - M - - - General stress
IOCDEKDB_01190 3.49e-158 ywaF - - S - - - Integral membrane protein
IOCDEKDB_01191 1.25e-114 ywaE - - K - - - Transcriptional regulator
IOCDEKDB_01192 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOCDEKDB_01193 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IOCDEKDB_01194 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IOCDEKDB_01195 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOCDEKDB_01196 1.08e-139 tmrB - - S - - - AAA domain
IOCDEKDB_01197 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOCDEKDB_01198 2.99e-117 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IOCDEKDB_01199 8.63e-97 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_01200 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IOCDEKDB_01201 1.33e-268 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IOCDEKDB_01202 2.38e-82 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IOCDEKDB_01203 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IOCDEKDB_01204 7.37e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IOCDEKDB_01205 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IOCDEKDB_01206 7.79e-105 ycgB - - - - - - -
IOCDEKDB_01207 0.0 ycgA - - S - - - Membrane
IOCDEKDB_01208 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IOCDEKDB_01209 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IOCDEKDB_01210 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IOCDEKDB_01211 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IOCDEKDB_01212 1.38e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IOCDEKDB_01213 1.19e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
IOCDEKDB_01214 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IOCDEKDB_01217 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
IOCDEKDB_01218 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IOCDEKDB_01219 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IOCDEKDB_01220 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IOCDEKDB_01221 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IOCDEKDB_01222 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IOCDEKDB_01223 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IOCDEKDB_01224 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOCDEKDB_01225 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOCDEKDB_01226 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_01227 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_01228 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IOCDEKDB_01229 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
IOCDEKDB_01230 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
IOCDEKDB_01231 3.12e-107 - - - K - - - Acetyltransferase (GNAT) domain
IOCDEKDB_01233 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IOCDEKDB_01234 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IOCDEKDB_01235 4.28e-163 - - - - - - - -
IOCDEKDB_01236 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IOCDEKDB_01237 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
IOCDEKDB_01238 1.24e-156 ydhC - - K - - - FCD
IOCDEKDB_01239 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IOCDEKDB_01240 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IOCDEKDB_01241 1.9e-89 - - - K - - - Winged helix DNA-binding domain
IOCDEKDB_01242 6.42e-147 ydgI - - C - - - nitroreductase
IOCDEKDB_01243 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IOCDEKDB_01244 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_01245 5.94e-118 - - - S - - - DinB family
IOCDEKDB_01246 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_01247 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IOCDEKDB_01248 8.04e-111 yycN - - K - - - Acetyltransferase
IOCDEKDB_01249 5.76e-70 - - - S - - - DoxX-like family
IOCDEKDB_01250 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
IOCDEKDB_01251 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
IOCDEKDB_01252 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
IOCDEKDB_01253 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IOCDEKDB_01254 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
IOCDEKDB_01255 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
IOCDEKDB_01256 1.78e-73 ydfR - - S - - - Protein of unknown function (DUF421)
IOCDEKDB_01258 2.17e-38 - - - - - - - -
IOCDEKDB_01259 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
IOCDEKDB_01260 2.57e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IOCDEKDB_01261 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IOCDEKDB_01262 0.0 ylaA - - - - - - -
IOCDEKDB_01263 1.44e-56 ylaB - - - - - - -
IOCDEKDB_01264 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_01266 1.74e-57 ylaE - - - - - - -
IOCDEKDB_01267 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
IOCDEKDB_01268 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IOCDEKDB_01269 4.4e-63 ylaH - - S - - - YlaH-like protein
IOCDEKDB_01270 8.92e-44 ylaI - - S - - - protein conserved in bacteria
IOCDEKDB_01271 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOCDEKDB_01272 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IOCDEKDB_01273 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IOCDEKDB_01274 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IOCDEKDB_01275 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
IOCDEKDB_01276 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IOCDEKDB_01277 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IOCDEKDB_01278 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IOCDEKDB_01279 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IOCDEKDB_01280 2.28e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IOCDEKDB_01281 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IOCDEKDB_01282 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IOCDEKDB_01283 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IOCDEKDB_01284 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IOCDEKDB_01285 1.88e-80 ylbA - - S - - - YugN-like family
IOCDEKDB_01286 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
IOCDEKDB_01287 2.18e-256 ylbC - - S - - - protein with SCP PR1 domains
IOCDEKDB_01288 3.24e-89 ylbD - - S - - - Putative coat protein
IOCDEKDB_01289 1.73e-48 ylbE - - S - - - YlbE-like protein
IOCDEKDB_01290 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
IOCDEKDB_01291 4.36e-52 ylbG - - S - - - UPF0298 protein
IOCDEKDB_01292 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IOCDEKDB_01293 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOCDEKDB_01294 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IOCDEKDB_01295 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IOCDEKDB_01296 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IOCDEKDB_01297 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
IOCDEKDB_01299 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IOCDEKDB_01300 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IOCDEKDB_01301 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IOCDEKDB_01302 1.33e-115 ylbP - - K - - - n-acetyltransferase
IOCDEKDB_01303 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOCDEKDB_01304 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IOCDEKDB_01305 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IOCDEKDB_01306 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOCDEKDB_01307 3.42e-68 ftsL - - D - - - Essential cell division protein
IOCDEKDB_01308 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IOCDEKDB_01309 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IOCDEKDB_01310 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOCDEKDB_01311 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOCDEKDB_01312 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOCDEKDB_01313 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IOCDEKDB_01314 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOCDEKDB_01315 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IOCDEKDB_01316 1.37e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOCDEKDB_01317 3.45e-146 ylxW - - S - - - protein conserved in bacteria
IOCDEKDB_01318 8.67e-132 ylxX - - S - - - protein conserved in bacteria
IOCDEKDB_01319 5.37e-76 sbp - - S - - - small basic protein
IOCDEKDB_01320 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOCDEKDB_01321 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOCDEKDB_01322 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IOCDEKDB_01324 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IOCDEKDB_01325 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_01326 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_01327 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IOCDEKDB_01328 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IOCDEKDB_01329 3.58e-51 ylmC - - S - - - sporulation protein
IOCDEKDB_01330 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IOCDEKDB_01331 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOCDEKDB_01332 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOCDEKDB_01333 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IOCDEKDB_01334 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
IOCDEKDB_01335 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IOCDEKDB_01336 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOCDEKDB_01337 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
IOCDEKDB_01338 1.89e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOCDEKDB_01339 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IOCDEKDB_01340 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOCDEKDB_01341 8.02e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IOCDEKDB_01342 5.99e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IOCDEKDB_01343 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOCDEKDB_01344 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IOCDEKDB_01345 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IOCDEKDB_01346 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IOCDEKDB_01347 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOCDEKDB_01348 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOCDEKDB_01349 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOCDEKDB_01350 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IOCDEKDB_01351 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IOCDEKDB_01352 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IOCDEKDB_01353 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IOCDEKDB_01354 1.45e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IOCDEKDB_01355 8.38e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IOCDEKDB_01356 3.78e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IOCDEKDB_01357 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IOCDEKDB_01358 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IOCDEKDB_01359 8.41e-202 yloC - - S - - - stress-induced protein
IOCDEKDB_01360 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IOCDEKDB_01361 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IOCDEKDB_01362 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOCDEKDB_01363 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOCDEKDB_01364 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOCDEKDB_01365 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOCDEKDB_01366 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOCDEKDB_01367 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOCDEKDB_01368 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IOCDEKDB_01369 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IOCDEKDB_01370 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IOCDEKDB_01371 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOCDEKDB_01372 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IOCDEKDB_01373 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IOCDEKDB_01374 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IOCDEKDB_01375 3.65e-78 yloU - - S - - - protein conserved in bacteria
IOCDEKDB_01376 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IOCDEKDB_01377 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IOCDEKDB_01378 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IOCDEKDB_01379 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOCDEKDB_01380 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IOCDEKDB_01381 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOCDEKDB_01382 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IOCDEKDB_01383 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IOCDEKDB_01384 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOCDEKDB_01385 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOCDEKDB_01386 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IOCDEKDB_01387 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOCDEKDB_01388 1.67e-114 - - - - - - - -
IOCDEKDB_01389 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOCDEKDB_01390 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOCDEKDB_01391 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IOCDEKDB_01392 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IOCDEKDB_01393 3.41e-80 ylqD - - S - - - YlqD protein
IOCDEKDB_01394 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOCDEKDB_01395 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IOCDEKDB_01396 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOCDEKDB_01397 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOCDEKDB_01398 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOCDEKDB_01399 0.0 ylqG - - - - - - -
IOCDEKDB_01400 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IOCDEKDB_01401 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IOCDEKDB_01402 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IOCDEKDB_01403 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IOCDEKDB_01404 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOCDEKDB_01405 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IOCDEKDB_01406 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IOCDEKDB_01407 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IOCDEKDB_01408 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IOCDEKDB_01409 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IOCDEKDB_01410 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IOCDEKDB_01411 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IOCDEKDB_01412 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IOCDEKDB_01413 1.07e-95 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IOCDEKDB_01414 7.5e-188 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IOCDEKDB_01415 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOCDEKDB_01416 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IOCDEKDB_01417 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IOCDEKDB_01418 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IOCDEKDB_01419 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
IOCDEKDB_01420 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IOCDEKDB_01421 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IOCDEKDB_01422 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IOCDEKDB_01423 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IOCDEKDB_01424 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IOCDEKDB_01425 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IOCDEKDB_01426 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IOCDEKDB_01427 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IOCDEKDB_01428 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IOCDEKDB_01429 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IOCDEKDB_01430 8.38e-148 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IOCDEKDB_01431 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOCDEKDB_01432 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IOCDEKDB_01433 1.89e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IOCDEKDB_01434 1.28e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IOCDEKDB_01435 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IOCDEKDB_01436 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IOCDEKDB_01437 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IOCDEKDB_01438 5.88e-54 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IOCDEKDB_01439 4.54e-60 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IOCDEKDB_01440 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IOCDEKDB_01441 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_01442 2.81e-100 ylxL - - - - - - -
IOCDEKDB_01443 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IOCDEKDB_01444 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOCDEKDB_01445 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IOCDEKDB_01446 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOCDEKDB_01447 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOCDEKDB_01448 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IOCDEKDB_01449 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IOCDEKDB_01450 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IOCDEKDB_01451 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOCDEKDB_01452 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOCDEKDB_01453 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IOCDEKDB_01454 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IOCDEKDB_01455 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IOCDEKDB_01456 6.16e-63 ylxQ - - J - - - ribosomal protein
IOCDEKDB_01457 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOCDEKDB_01458 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IOCDEKDB_01459 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOCDEKDB_01460 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOCDEKDB_01461 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IOCDEKDB_01462 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOCDEKDB_01463 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IOCDEKDB_01464 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IOCDEKDB_01465 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
IOCDEKDB_01466 1.53e-56 ymxH - - S - - - YlmC YmxH family
IOCDEKDB_01467 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IOCDEKDB_01468 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IOCDEKDB_01469 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOCDEKDB_01470 2.83e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IOCDEKDB_01471 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOCDEKDB_01472 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOCDEKDB_01473 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IOCDEKDB_01474 4.94e-44 - - - S - - - YlzJ-like protein
IOCDEKDB_01475 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IOCDEKDB_01476 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_01477 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_01478 9.47e-299 albE - - S - - - Peptidase M16
IOCDEKDB_01479 2.37e-309 ymfH - - S - - - zinc protease
IOCDEKDB_01480 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IOCDEKDB_01481 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
IOCDEKDB_01482 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
IOCDEKDB_01483 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IOCDEKDB_01484 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOCDEKDB_01485 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IOCDEKDB_01486 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOCDEKDB_01487 1.82e-276 pbpX - - V - - - Beta-lactamase
IOCDEKDB_01488 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IOCDEKDB_01489 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IOCDEKDB_01490 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IOCDEKDB_01491 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IOCDEKDB_01492 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOCDEKDB_01493 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IOCDEKDB_01494 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IOCDEKDB_01495 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IOCDEKDB_01496 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOCDEKDB_01497 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOCDEKDB_01502 5.52e-31 - - - M - - - ArpU family transcriptional regulator
IOCDEKDB_01503 5.89e-58 - - - L - - - Phage integrase family
IOCDEKDB_01512 1.04e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
IOCDEKDB_01513 1.36e-87 - - - L - - - Integrase
IOCDEKDB_01514 3.64e-138 - - - S - - - Helix-turn-helix domain
IOCDEKDB_01515 7.01e-128 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
IOCDEKDB_01516 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IOCDEKDB_01517 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOCDEKDB_01518 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOCDEKDB_01519 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IOCDEKDB_01520 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IOCDEKDB_01521 5.44e-74 yuzD - - S - - - protein conserved in bacteria
IOCDEKDB_01522 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IOCDEKDB_01523 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IOCDEKDB_01524 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOCDEKDB_01525 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IOCDEKDB_01526 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IOCDEKDB_01527 1.55e-253 yutH - - S - - - Spore coat protein
IOCDEKDB_01528 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IOCDEKDB_01529 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOCDEKDB_01530 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
IOCDEKDB_01531 3.2e-63 yutD - - S - - - protein conserved in bacteria
IOCDEKDB_01532 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOCDEKDB_01533 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IOCDEKDB_01534 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IOCDEKDB_01535 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IOCDEKDB_01536 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
IOCDEKDB_01537 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IOCDEKDB_01538 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IOCDEKDB_01539 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
IOCDEKDB_01540 3.06e-79 yunG - - - - - - -
IOCDEKDB_01541 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IOCDEKDB_01542 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IOCDEKDB_01543 1.7e-297 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
IOCDEKDB_01544 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IOCDEKDB_01545 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IOCDEKDB_01546 8.84e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IOCDEKDB_01547 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IOCDEKDB_01548 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IOCDEKDB_01549 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IOCDEKDB_01550 6.07e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IOCDEKDB_01551 8.43e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IOCDEKDB_01552 5.27e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IOCDEKDB_01553 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IOCDEKDB_01554 6.85e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IOCDEKDB_01555 7.63e-217 bsn - - L - - - Ribonuclease
IOCDEKDB_01556 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_01557 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IOCDEKDB_01558 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IOCDEKDB_01559 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IOCDEKDB_01560 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IOCDEKDB_01561 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IOCDEKDB_01562 1e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IOCDEKDB_01563 3.71e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IOCDEKDB_01564 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IOCDEKDB_01565 3.9e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IOCDEKDB_01567 3.35e-56 - - - - - - - -
IOCDEKDB_01568 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_01569 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IOCDEKDB_01570 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IOCDEKDB_01571 1.79e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IOCDEKDB_01572 1.63e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOCDEKDB_01573 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IOCDEKDB_01574 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IOCDEKDB_01575 6.44e-62 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOCDEKDB_01576 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IOCDEKDB_01577 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IOCDEKDB_01578 1.76e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOCDEKDB_01579 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
IOCDEKDB_01580 8.14e-73 yusE - - CO - - - Thioredoxin
IOCDEKDB_01581 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IOCDEKDB_01582 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
IOCDEKDB_01583 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IOCDEKDB_01584 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IOCDEKDB_01585 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IOCDEKDB_01586 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IOCDEKDB_01587 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IOCDEKDB_01588 1.11e-13 - - - S - - - YuzL-like protein
IOCDEKDB_01589 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IOCDEKDB_01590 2.23e-54 - - - - - - - -
IOCDEKDB_01591 8.66e-70 yusN - - M - - - Coat F domain
IOCDEKDB_01592 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IOCDEKDB_01593 0.0 yusP - - P - - - Major facilitator superfamily
IOCDEKDB_01594 4.86e-84 yusQ - - S - - - Tautomerase enzyme
IOCDEKDB_01595 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_01596 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IOCDEKDB_01597 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
IOCDEKDB_01598 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IOCDEKDB_01599 3.48e-88 - - - S - - - YusW-like protein
IOCDEKDB_01600 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IOCDEKDB_01602 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IOCDEKDB_01603 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
IOCDEKDB_01604 6.4e-09 - - - J - - - O-methyltransferase
IOCDEKDB_01605 2.94e-17 - - - EGP - - - Major Facilitator
IOCDEKDB_01607 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
IOCDEKDB_01609 1.26e-18 - - - - - - - -
IOCDEKDB_01610 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IOCDEKDB_01611 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_01612 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
IOCDEKDB_01613 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOCDEKDB_01614 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_01615 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_01616 3.06e-204 yuxN - - K - - - Transcriptional regulator
IOCDEKDB_01617 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOCDEKDB_01618 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
IOCDEKDB_01619 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IOCDEKDB_01620 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IOCDEKDB_01621 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IOCDEKDB_01622 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_01623 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_01624 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IOCDEKDB_01625 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IOCDEKDB_01626 1.41e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IOCDEKDB_01627 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IOCDEKDB_01628 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_01629 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IOCDEKDB_01630 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IOCDEKDB_01631 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_01632 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IOCDEKDB_01633 1.01e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_01634 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IOCDEKDB_01635 0.0 yvrG - - T - - - Histidine kinase
IOCDEKDB_01636 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_01637 6.67e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IOCDEKDB_01638 3.46e-26 - - - S - - - YvrJ protein family
IOCDEKDB_01639 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IOCDEKDB_01640 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
IOCDEKDB_01641 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IOCDEKDB_01642 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_01643 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
IOCDEKDB_01644 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IOCDEKDB_01645 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_01646 3.87e-233 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_01647 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_01648 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IOCDEKDB_01649 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IOCDEKDB_01650 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IOCDEKDB_01651 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IOCDEKDB_01652 3.46e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IOCDEKDB_01653 6.03e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IOCDEKDB_01654 1.74e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IOCDEKDB_01655 7.23e-200 yvgN - - S - - - reductase
IOCDEKDB_01656 9.32e-112 yvgO - - - - - - -
IOCDEKDB_01657 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IOCDEKDB_01658 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IOCDEKDB_01659 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IOCDEKDB_01660 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IOCDEKDB_01662 2.34e-139 yvgT - - S - - - membrane
IOCDEKDB_01663 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IOCDEKDB_01664 3.45e-137 bdbD - - O - - - Thioredoxin
IOCDEKDB_01665 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IOCDEKDB_01666 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IOCDEKDB_01667 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
IOCDEKDB_01668 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IOCDEKDB_01669 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IOCDEKDB_01670 8.02e-107 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOCDEKDB_01671 4.87e-34 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOCDEKDB_01672 0.0 - - - S - - - Fusaric acid resistance protein-like
IOCDEKDB_01673 1.01e-64 yvaD - - S - - - Family of unknown function (DUF5360)
IOCDEKDB_01674 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IOCDEKDB_01675 1.64e-125 - - - K - - - Bacterial regulatory proteins, tetR family
IOCDEKDB_01676 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_01679 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IOCDEKDB_01682 6.14e-142 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_01683 1.79e-74 - - - S - - - Bacteriophage holin family
IOCDEKDB_01685 5.3e-47 - - - - - - - -
IOCDEKDB_01686 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IOCDEKDB_01687 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IOCDEKDB_01688 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IOCDEKDB_01689 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOCDEKDB_01690 5.14e-161 yfmS - - NT - - - chemotaxis protein
IOCDEKDB_01691 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOCDEKDB_01692 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
IOCDEKDB_01693 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IOCDEKDB_01694 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_01695 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IOCDEKDB_01696 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
IOCDEKDB_01697 5.44e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IOCDEKDB_01698 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IOCDEKDB_01699 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IOCDEKDB_01700 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IOCDEKDB_01701 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IOCDEKDB_01702 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
IOCDEKDB_01719 1.23e-182 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
IOCDEKDB_01720 1.58e-36 - - - - - - - -
IOCDEKDB_01721 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IOCDEKDB_01722 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IOCDEKDB_01724 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IOCDEKDB_01725 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IOCDEKDB_01726 2.82e-216 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IOCDEKDB_01727 1.13e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IOCDEKDB_01728 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IOCDEKDB_01730 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOCDEKDB_01731 3.81e-100 ygaO - - - - - - -
IOCDEKDB_01732 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_01734 8.77e-144 yhzB - - S - - - B3/4 domain
IOCDEKDB_01735 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IOCDEKDB_01736 9.27e-224 yhbB - - S - - - Putative amidase domain
IOCDEKDB_01737 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOCDEKDB_01738 5.64e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
IOCDEKDB_01739 3.77e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IOCDEKDB_01740 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IOCDEKDB_01741 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IOCDEKDB_01742 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IOCDEKDB_01743 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IOCDEKDB_01744 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IOCDEKDB_01745 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IOCDEKDB_01746 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
IOCDEKDB_01747 3.95e-59 yhcC - - - - - - -
IOCDEKDB_01748 2.06e-69 - - - - - - - -
IOCDEKDB_01749 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_01750 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_01751 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_01752 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOCDEKDB_01753 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IOCDEKDB_01754 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IOCDEKDB_01755 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IOCDEKDB_01756 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOCDEKDB_01757 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
IOCDEKDB_01758 1.5e-81 - - - S - - - Immunity protein 70
IOCDEKDB_01762 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
IOCDEKDB_01764 4.39e-37 yddA - - - - - - -
IOCDEKDB_01768 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
IOCDEKDB_01769 9.78e-54 yddC - - - - - - -
IOCDEKDB_01770 6.91e-118 yddD - - S - - - TcpE family
IOCDEKDB_01771 1.59e-270 yddE - - S - - - AAA-like domain
IOCDEKDB_01772 2.21e-242 yddE - - S - - - AAA-like domain
IOCDEKDB_01773 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
IOCDEKDB_01774 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOCDEKDB_01775 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IOCDEKDB_01776 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IOCDEKDB_01777 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IOCDEKDB_01778 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IOCDEKDB_01779 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IOCDEKDB_01780 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IOCDEKDB_01781 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
IOCDEKDB_01782 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
IOCDEKDB_01783 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IOCDEKDB_01784 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
IOCDEKDB_01785 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IOCDEKDB_01786 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IOCDEKDB_01787 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IOCDEKDB_01788 1.92e-08 - - - - - - - -
IOCDEKDB_01789 7.41e-37 - - - S - - - Protein of unknown function (DUF3813)
IOCDEKDB_01790 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
IOCDEKDB_01791 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IOCDEKDB_01792 4.16e-198 yitS - - S - - - protein conserved in bacteria
IOCDEKDB_01793 7.32e-49 yitR - - S - - - Domain of unknown function (DUF3784)
IOCDEKDB_01795 1.59e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IOCDEKDB_01796 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IOCDEKDB_01797 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IOCDEKDB_01798 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
IOCDEKDB_01799 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
IOCDEKDB_01800 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOCDEKDB_01801 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
IOCDEKDB_01802 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_01803 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IOCDEKDB_01804 1.41e-119 yisT - - S - - - DinB family
IOCDEKDB_01805 2.11e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IOCDEKDB_01806 5.88e-232 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IOCDEKDB_01807 1.16e-206 yisR - - K - - - Transcriptional regulator
IOCDEKDB_01808 7.14e-311 yisQ - - V - - - Mate efflux family protein
IOCDEKDB_01809 4.02e-151 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IOCDEKDB_01810 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IOCDEKDB_01811 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
IOCDEKDB_01812 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IOCDEKDB_01813 1.44e-74 yisL - - S - - - UPF0344 protein
IOCDEKDB_01814 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IOCDEKDB_01815 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
IOCDEKDB_01816 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
IOCDEKDB_01817 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IOCDEKDB_01818 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
IOCDEKDB_01819 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IOCDEKDB_01820 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IOCDEKDB_01821 3.92e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IOCDEKDB_01822 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IOCDEKDB_01823 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
IOCDEKDB_01824 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IOCDEKDB_01825 1.34e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOCDEKDB_01826 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IOCDEKDB_01827 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IOCDEKDB_01828 9.3e-102 yhjR - - S - - - Rubrerythrin
IOCDEKDB_01829 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IOCDEKDB_01830 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IOCDEKDB_01831 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
IOCDEKDB_01832 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IOCDEKDB_01833 1.89e-211 rsgI - - S - - - Anti-sigma factor N-terminus
IOCDEKDB_01834 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_01835 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IOCDEKDB_01836 1.71e-143 ykoX - - S - - - membrane-associated protein
IOCDEKDB_01837 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
IOCDEKDB_01838 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IOCDEKDB_01839 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IOCDEKDB_01840 3.86e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IOCDEKDB_01841 0.0 ykoS - - - - - - -
IOCDEKDB_01842 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IOCDEKDB_01843 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
IOCDEKDB_01844 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IOCDEKDB_01845 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IOCDEKDB_01846 3.04e-36 ykoL - - - - - - -
IOCDEKDB_01847 1.63e-25 - - - - - - - -
IOCDEKDB_01848 1.49e-70 tnrA - - K - - - transcriptional
IOCDEKDB_01849 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IOCDEKDB_01851 1.45e-08 - - - - - - - -
IOCDEKDB_01852 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
IOCDEKDB_01853 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
IOCDEKDB_01854 6.32e-309 ykoH - - T - - - Histidine kinase
IOCDEKDB_01855 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_01856 1.21e-142 ykoF - - S - - - YKOF-related Family
IOCDEKDB_01857 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IOCDEKDB_01858 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_01859 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IOCDEKDB_01860 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOCDEKDB_01861 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IOCDEKDB_01862 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOCDEKDB_01863 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
IOCDEKDB_01864 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
IOCDEKDB_01865 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
IOCDEKDB_01866 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IOCDEKDB_01867 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOCDEKDB_01868 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOCDEKDB_01869 2.76e-216 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IOCDEKDB_01870 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IOCDEKDB_01871 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IOCDEKDB_01872 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOCDEKDB_01873 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
IOCDEKDB_01874 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
IOCDEKDB_01875 9.93e-15 - - - - - - - -
IOCDEKDB_01876 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IOCDEKDB_01877 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
IOCDEKDB_01878 9.79e-102 ykgA - - E - - - Amidinotransferase
IOCDEKDB_01879 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IOCDEKDB_01880 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_01881 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IOCDEKDB_01882 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IOCDEKDB_01883 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IOCDEKDB_01885 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IOCDEKDB_01886 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_01887 1.23e-223 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_01888 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_01889 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IOCDEKDB_01890 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
IOCDEKDB_01891 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOCDEKDB_01893 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IOCDEKDB_01894 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IOCDEKDB_01895 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IOCDEKDB_01896 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
IOCDEKDB_01897 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IOCDEKDB_01898 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
IOCDEKDB_01899 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IOCDEKDB_01900 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IOCDEKDB_01901 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_01902 1.15e-52 xhlB - - S - - - SPP1 phage holin
IOCDEKDB_01903 2.21e-51 xhlA - - S - - - Haemolysin XhlA
IOCDEKDB_01904 9.79e-195 xepA - - - - - - -
IOCDEKDB_01905 6.35e-31 xkdX - - - - - - -
IOCDEKDB_01906 2.7e-68 xkdW - - S - - - XkdW protein
IOCDEKDB_01907 0.0 - - - - - - - -
IOCDEKDB_01908 4.43e-56 - - - - - - - -
IOCDEKDB_01909 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IOCDEKDB_01910 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IOCDEKDB_01911 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
IOCDEKDB_01912 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
IOCDEKDB_01913 2.31e-232 xkdQ - - G - - - NLP P60 protein
IOCDEKDB_01914 1.73e-151 xkdP - - S - - - Lysin motif
IOCDEKDB_01915 0.0 xkdO - - L - - - Transglycosylase SLT domain
IOCDEKDB_01916 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IOCDEKDB_01917 2.45e-98 xkdM - - S - - - Phage tail tube protein
IOCDEKDB_01918 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
IOCDEKDB_01919 2.36e-100 xkdJ - - - - - - -
IOCDEKDB_01920 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IOCDEKDB_01921 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
IOCDEKDB_01922 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
IOCDEKDB_01923 3.91e-217 xkdG - - S - - - Phage capsid family
IOCDEKDB_01924 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
IOCDEKDB_01925 0.0 yqbA - - S - - - portal protein
IOCDEKDB_01926 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IOCDEKDB_01927 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IOCDEKDB_01928 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IOCDEKDB_01932 4.14e-150 xkdC - - L - - - Bacterial dnaA protein
IOCDEKDB_01933 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
IOCDEKDB_01935 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
IOCDEKDB_01936 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
IOCDEKDB_01937 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
IOCDEKDB_01938 1.11e-138 yjqB - - S - - - Pfam:DUF867
IOCDEKDB_01939 1.35e-80 yjqA - - S - - - Bacterial PH domain
IOCDEKDB_01940 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IOCDEKDB_01941 1.09e-34 - - - S - - - YCII-related domain
IOCDEKDB_01943 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_01944 6.67e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IOCDEKDB_01945 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_01946 1.86e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_01947 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IOCDEKDB_01948 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_01949 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOCDEKDB_01950 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IOCDEKDB_01951 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_01952 1.39e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IOCDEKDB_01954 2.69e-229 ykvZ - - K - - - Transcriptional regulator
IOCDEKDB_01955 2.74e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IOCDEKDB_01956 3.99e-09 - - - - - - - -
IOCDEKDB_01957 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IOCDEKDB_01958 2.76e-115 stoA - - CO - - - thiol-disulfide
IOCDEKDB_01959 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_01960 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IOCDEKDB_01961 2.6e-39 - - - - - - - -
IOCDEKDB_01962 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IOCDEKDB_01963 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
IOCDEKDB_01964 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IOCDEKDB_01965 1.69e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IOCDEKDB_01966 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IOCDEKDB_01967 4.34e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IOCDEKDB_01968 1.94e-226 ykvI - - S - - - membrane
IOCDEKDB_01969 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IOCDEKDB_01970 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IOCDEKDB_01971 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IOCDEKDB_01972 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IOCDEKDB_01973 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IOCDEKDB_01974 7.14e-75 eag - - - - - - -
IOCDEKDB_01976 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
IOCDEKDB_01977 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IOCDEKDB_01978 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IOCDEKDB_01979 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IOCDEKDB_01980 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IOCDEKDB_01981 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IOCDEKDB_01982 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOCDEKDB_01983 6.78e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IOCDEKDB_01984 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IOCDEKDB_01986 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IOCDEKDB_01987 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_01988 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IOCDEKDB_01989 4.83e-30 ykzE - - - - - - -
IOCDEKDB_01991 8.32e-151 ykwD - - J - - - protein with SCP PR1 domains
IOCDEKDB_01992 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IOCDEKDB_01993 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_01994 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IOCDEKDB_01995 1.05e-22 - - - - - - - -
IOCDEKDB_01996 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IOCDEKDB_01997 3.71e-110 ykyB - - S - - - YkyB-like protein
IOCDEKDB_01998 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_01999 5.84e-115 ykuD - - S - - - protein conserved in bacteria
IOCDEKDB_02000 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IOCDEKDB_02001 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02002 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
IOCDEKDB_02003 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
IOCDEKDB_02004 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
IOCDEKDB_02005 7.83e-38 ykzF - - S - - - Antirepressor AbbA
IOCDEKDB_02006 6.01e-99 ykuL - - S - - - CBS domain
IOCDEKDB_02007 7.61e-215 ccpC - - K - - - Transcriptional regulator
IOCDEKDB_02008 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
IOCDEKDB_02009 1.74e-222 ykuO - - - - - - -
IOCDEKDB_02010 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
IOCDEKDB_02011 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOCDEKDB_02012 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOCDEKDB_02013 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
IOCDEKDB_02014 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IOCDEKDB_02015 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
IOCDEKDB_02016 4.23e-104 ykuV - - CO - - - thiol-disulfide
IOCDEKDB_02017 4.71e-122 rok - - K - - - Repressor of ComK
IOCDEKDB_02018 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOCDEKDB_02019 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IOCDEKDB_02020 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IOCDEKDB_02021 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IOCDEKDB_02022 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IOCDEKDB_02023 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IOCDEKDB_02024 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IOCDEKDB_02025 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IOCDEKDB_02026 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IOCDEKDB_02027 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IOCDEKDB_02028 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_02029 9.03e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02030 6.59e-67 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02031 9.7e-88 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02032 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IOCDEKDB_02033 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
IOCDEKDB_02034 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_02035 1.13e-89 - - - - - - - -
IOCDEKDB_02036 2.66e-28 yxeD - - - - - - -
IOCDEKDB_02037 7.32e-42 yxeE - - - - - - -
IOCDEKDB_02040 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
IOCDEKDB_02041 3.87e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IOCDEKDB_02042 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOCDEKDB_02043 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_02044 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IOCDEKDB_02045 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IOCDEKDB_02046 1.13e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02047 2.89e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IOCDEKDB_02048 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
IOCDEKDB_02049 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
IOCDEKDB_02050 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
IOCDEKDB_02051 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOCDEKDB_02052 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOCDEKDB_02053 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOCDEKDB_02054 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IOCDEKDB_02055 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IOCDEKDB_02056 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IOCDEKDB_02057 7.08e-307 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_02058 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
IOCDEKDB_02059 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOCDEKDB_02060 0.0 - - - L - - - HKD family nuclease
IOCDEKDB_02061 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
IOCDEKDB_02062 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
IOCDEKDB_02063 7.83e-269 - - - S - - - nuclease activity
IOCDEKDB_02065 1.83e-221 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
IOCDEKDB_02066 3.36e-68 - - - - - - - -
IOCDEKDB_02067 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_02068 2.15e-115 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IOCDEKDB_02069 2.02e-217 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IOCDEKDB_02070 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
IOCDEKDB_02071 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
IOCDEKDB_02072 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02073 5.69e-208 yxxF - - EG - - - EamA-like transporter family
IOCDEKDB_02074 0.0 wapA - - M - - - COG3209 Rhs family protein
IOCDEKDB_02075 3.29e-19 yxiJ - - S - - - YxiJ-like protein
IOCDEKDB_02076 2.23e-99 wapA - - M - - - COG3209 Rhs family protein
IOCDEKDB_02077 1.27e-69 - - - - - - - -
IOCDEKDB_02079 6.44e-178 - - - - - - - -
IOCDEKDB_02080 5.36e-120 - - - S - - - Protein of unknown function (DUF4240)
IOCDEKDB_02081 7.13e-100 - - - - - - - -
IOCDEKDB_02082 4.48e-58 - - - - - - - -
IOCDEKDB_02083 4.67e-89 yxiG - - - - - - -
IOCDEKDB_02084 9.7e-68 yxxG - - - - - - -
IOCDEKDB_02085 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
IOCDEKDB_02088 8.22e-181 - - - - - - - -
IOCDEKDB_02089 1.01e-120 yxiI - - S - - - Protein of unknown function (DUF2716)
IOCDEKDB_02090 1.86e-40 - - - - - - - -
IOCDEKDB_02093 4.06e-58 yxiJ - - S - - - YxiJ-like protein
IOCDEKDB_02096 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
IOCDEKDB_02097 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IOCDEKDB_02098 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IOCDEKDB_02099 1.07e-142 - - - - - - - -
IOCDEKDB_02100 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IOCDEKDB_02101 7.21e-183 bglS - - M - - - licheninase activity
IOCDEKDB_02102 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IOCDEKDB_02103 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IOCDEKDB_02104 2.28e-63 yxiS - - - - - - -
IOCDEKDB_02105 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
IOCDEKDB_02106 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IOCDEKDB_02107 2.42e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IOCDEKDB_02108 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IOCDEKDB_02109 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IOCDEKDB_02110 3.99e-149 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOCDEKDB_02111 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IOCDEKDB_02112 3.66e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IOCDEKDB_02113 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IOCDEKDB_02114 2.88e-111 yxjI - - S - - - LURP-one-related
IOCDEKDB_02117 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IOCDEKDB_02118 6.34e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
IOCDEKDB_02119 6.98e-243 - - - T - - - Signal transduction histidine kinase
IOCDEKDB_02120 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
IOCDEKDB_02121 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IOCDEKDB_02122 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IOCDEKDB_02123 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IOCDEKDB_02124 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IOCDEKDB_02125 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_02126 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
IOCDEKDB_02128 0.0 - - - O - - - Peptidase family M48
IOCDEKDB_02129 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
IOCDEKDB_02130 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IOCDEKDB_02131 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IOCDEKDB_02132 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IOCDEKDB_02133 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IOCDEKDB_02134 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOCDEKDB_02135 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IOCDEKDB_02136 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_02137 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
IOCDEKDB_02138 1.63e-39 - - - - - - - -
IOCDEKDB_02139 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
IOCDEKDB_02140 2.01e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02141 1.55e-176 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IOCDEKDB_02142 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
IOCDEKDB_02143 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IOCDEKDB_02144 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IOCDEKDB_02145 1.05e-26 yxzF - - - - - - -
IOCDEKDB_02146 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IOCDEKDB_02147 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IOCDEKDB_02148 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOCDEKDB_02149 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_02150 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOCDEKDB_02151 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IOCDEKDB_02152 1.22e-81 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_02153 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_02154 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOCDEKDB_02155 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_02156 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IOCDEKDB_02157 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_02159 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IOCDEKDB_02160 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
IOCDEKDB_02161 2.15e-63 ytpI - - S - - - YtpI-like protein
IOCDEKDB_02162 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IOCDEKDB_02163 1.15e-39 - - - - - - - -
IOCDEKDB_02164 5.12e-112 ytrI - - - - - - -
IOCDEKDB_02165 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
IOCDEKDB_02166 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IOCDEKDB_02167 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IOCDEKDB_02168 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOCDEKDB_02169 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IOCDEKDB_02170 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IOCDEKDB_02171 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IOCDEKDB_02172 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IOCDEKDB_02173 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
IOCDEKDB_02174 4.46e-93 ytwI - - S - - - membrane
IOCDEKDB_02175 3.34e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IOCDEKDB_02176 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IOCDEKDB_02177 4.23e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IOCDEKDB_02178 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_02179 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IOCDEKDB_02180 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOCDEKDB_02181 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOCDEKDB_02182 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IOCDEKDB_02183 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOCDEKDB_02184 4.54e-205 ytbE - - S - - - reductase
IOCDEKDB_02185 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IOCDEKDB_02186 1.64e-86 ytcD - - K - - - Transcriptional regulator
IOCDEKDB_02187 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOCDEKDB_02188 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IOCDEKDB_02189 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOCDEKDB_02190 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IOCDEKDB_02191 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IOCDEKDB_02192 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
IOCDEKDB_02193 5.5e-202 ytxC - - S - - - YtxC-like family
IOCDEKDB_02195 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOCDEKDB_02196 1.15e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IOCDEKDB_02197 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02198 4.62e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IOCDEKDB_02199 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOCDEKDB_02200 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IOCDEKDB_02202 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOCDEKDB_02203 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IOCDEKDB_02204 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOCDEKDB_02205 3.65e-59 ysdA - - S - - - Membrane
IOCDEKDB_02206 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
IOCDEKDB_02207 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
IOCDEKDB_02208 4.74e-72 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_02209 5.69e-126 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_02210 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IOCDEKDB_02211 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IOCDEKDB_02212 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IOCDEKDB_02213 5.81e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IOCDEKDB_02214 1.24e-280 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IOCDEKDB_02215 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IOCDEKDB_02216 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IOCDEKDB_02217 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IOCDEKDB_02218 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IOCDEKDB_02219 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IOCDEKDB_02221 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
IOCDEKDB_02222 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IOCDEKDB_02223 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
IOCDEKDB_02224 1.11e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IOCDEKDB_02225 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IOCDEKDB_02226 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOCDEKDB_02227 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOCDEKDB_02228 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOCDEKDB_02229 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOCDEKDB_02230 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IOCDEKDB_02231 3.12e-111 yshB - - S - - - membrane protein, required for colicin V production
IOCDEKDB_02232 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IOCDEKDB_02233 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOCDEKDB_02234 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
IOCDEKDB_02235 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOCDEKDB_02236 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_02237 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IOCDEKDB_02238 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IOCDEKDB_02239 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IOCDEKDB_02241 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IOCDEKDB_02242 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IOCDEKDB_02243 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOCDEKDB_02244 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IOCDEKDB_02245 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
IOCDEKDB_02246 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IOCDEKDB_02247 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IOCDEKDB_02248 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IOCDEKDB_02249 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IOCDEKDB_02250 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_02251 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_02252 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IOCDEKDB_02253 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IOCDEKDB_02254 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IOCDEKDB_02255 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOCDEKDB_02256 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IOCDEKDB_02258 3.17e-170 - - - L - - - Phage integrase family
IOCDEKDB_02261 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IOCDEKDB_02262 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
IOCDEKDB_02263 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
IOCDEKDB_02264 3.84e-87 res - - L - - - Resolvase, N terminal domain
IOCDEKDB_02265 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IOCDEKDB_02266 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOCDEKDB_02267 1.81e-41 yazB - - K - - - transcriptional
IOCDEKDB_02268 7.57e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IOCDEKDB_02269 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOCDEKDB_02270 3.19e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IOCDEKDB_02271 1.32e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IOCDEKDB_02272 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IOCDEKDB_02273 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOCDEKDB_02274 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IOCDEKDB_02275 4.17e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IOCDEKDB_02276 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOCDEKDB_02277 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IOCDEKDB_02278 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOCDEKDB_02279 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IOCDEKDB_02280 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOCDEKDB_02281 3.83e-233 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IOCDEKDB_02282 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IOCDEKDB_02283 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IOCDEKDB_02286 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IOCDEKDB_02287 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IOCDEKDB_02288 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
IOCDEKDB_02289 1.91e-66 yabP - - S - - - Sporulation protein YabP
IOCDEKDB_02290 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IOCDEKDB_02291 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IOCDEKDB_02292 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_02293 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IOCDEKDB_02294 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOCDEKDB_02295 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
IOCDEKDB_02296 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOCDEKDB_02297 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IOCDEKDB_02298 3.51e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOCDEKDB_02299 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOCDEKDB_02300 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IOCDEKDB_02301 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IOCDEKDB_02302 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IOCDEKDB_02303 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOCDEKDB_02304 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
IOCDEKDB_02305 5.32e-53 veg - - S - - - protein conserved in bacteria
IOCDEKDB_02306 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
IOCDEKDB_02307 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOCDEKDB_02308 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOCDEKDB_02309 1.91e-283 yabE - - T - - - protein conserved in bacteria
IOCDEKDB_02310 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IOCDEKDB_02311 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOCDEKDB_02312 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IOCDEKDB_02313 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOCDEKDB_02314 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IOCDEKDB_02315 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IOCDEKDB_02316 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IOCDEKDB_02317 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
IOCDEKDB_02318 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IOCDEKDB_02319 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IOCDEKDB_02320 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
IOCDEKDB_02321 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOCDEKDB_02322 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IOCDEKDB_02323 1.19e-258 yaaN - - P - - - Belongs to the TelA family
IOCDEKDB_02324 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IOCDEKDB_02325 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IOCDEKDB_02326 1.73e-13 - - - - - - - -
IOCDEKDB_02327 3.96e-84 - - - O - - - Papain family cysteine protease
IOCDEKDB_02329 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
IOCDEKDB_02330 3.82e-37 - - - - - - - -
IOCDEKDB_02332 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOCDEKDB_02334 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
IOCDEKDB_02336 5.37e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IOCDEKDB_02337 5.98e-72 ypuD - - - - - - -
IOCDEKDB_02338 5.92e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOCDEKDB_02339 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IOCDEKDB_02340 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IOCDEKDB_02341 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOCDEKDB_02342 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_02343 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IOCDEKDB_02344 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOCDEKDB_02345 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOCDEKDB_02346 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
IOCDEKDB_02347 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IOCDEKDB_02348 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IOCDEKDB_02349 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IOCDEKDB_02350 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IOCDEKDB_02351 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IOCDEKDB_02352 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IOCDEKDB_02353 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IOCDEKDB_02354 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_02355 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02356 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_02357 8.13e-245 rsiX - - - - - - -
IOCDEKDB_02358 2.28e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IOCDEKDB_02359 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCDEKDB_02360 1.78e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOCDEKDB_02361 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IOCDEKDB_02362 1.28e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IOCDEKDB_02363 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IOCDEKDB_02364 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IOCDEKDB_02365 5.04e-148 ypbE - - M - - - Lysin motif
IOCDEKDB_02366 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
IOCDEKDB_02367 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IOCDEKDB_02368 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOCDEKDB_02369 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IOCDEKDB_02370 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IOCDEKDB_02371 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IOCDEKDB_02372 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IOCDEKDB_02373 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IOCDEKDB_02374 2.57e-141 ypfA - - M - - - Flagellar protein YcgR
IOCDEKDB_02375 4.83e-30 - - - S - - - Family of unknown function (DUF5359)
IOCDEKDB_02376 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IOCDEKDB_02377 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IOCDEKDB_02378 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOCDEKDB_02379 1.13e-11 - - - S - - - YpzI-like protein
IOCDEKDB_02380 1.11e-133 yphA - - - - - - -
IOCDEKDB_02381 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
IOCDEKDB_02382 2.06e-38 ypzH - - - - - - -
IOCDEKDB_02383 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IOCDEKDB_02384 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IOCDEKDB_02385 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
IOCDEKDB_02386 8.71e-176 yphF - - - - - - -
IOCDEKDB_02387 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IOCDEKDB_02388 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOCDEKDB_02389 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IOCDEKDB_02390 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IOCDEKDB_02391 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IOCDEKDB_02392 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOCDEKDB_02393 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IOCDEKDB_02394 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IOCDEKDB_02395 1.5e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IOCDEKDB_02396 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOCDEKDB_02397 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IOCDEKDB_02398 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IOCDEKDB_02399 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IOCDEKDB_02400 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IOCDEKDB_02401 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IOCDEKDB_02402 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IOCDEKDB_02403 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IOCDEKDB_02404 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IOCDEKDB_02405 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IOCDEKDB_02406 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IOCDEKDB_02407 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOCDEKDB_02408 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
IOCDEKDB_02409 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
IOCDEKDB_02410 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
IOCDEKDB_02411 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IOCDEKDB_02412 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IOCDEKDB_02413 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IOCDEKDB_02414 1.15e-125 ypjA - - S - - - membrane
IOCDEKDB_02415 6.56e-181 ypjB - - S - - - sporulation protein
IOCDEKDB_02416 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IOCDEKDB_02417 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IOCDEKDB_02418 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOCDEKDB_02419 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IOCDEKDB_02420 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IOCDEKDB_02421 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IOCDEKDB_02422 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOCDEKDB_02423 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOCDEKDB_02424 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IOCDEKDB_02425 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IOCDEKDB_02426 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IOCDEKDB_02427 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IOCDEKDB_02428 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IOCDEKDB_02429 2.66e-102 ypmB - - S - - - protein conserved in bacteria
IOCDEKDB_02430 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IOCDEKDB_02431 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IOCDEKDB_02432 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IOCDEKDB_02433 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOCDEKDB_02434 1.43e-121 ypoC - - - - - - -
IOCDEKDB_02435 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IOCDEKDB_02436 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOCDEKDB_02437 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
IOCDEKDB_02440 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
IOCDEKDB_02441 9.21e-11 - - - S - - - YppF-like protein
IOCDEKDB_02442 8.72e-68 yppG - - S - - - YppG-like protein
IOCDEKDB_02443 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IOCDEKDB_02444 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IOCDEKDB_02445 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IOCDEKDB_02446 1.98e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IOCDEKDB_02447 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
IOCDEKDB_02448 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOCDEKDB_02449 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IOCDEKDB_02451 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IOCDEKDB_02452 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02453 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IOCDEKDB_02454 1.57e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
IOCDEKDB_02455 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IOCDEKDB_02456 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IOCDEKDB_02457 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IOCDEKDB_02458 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IOCDEKDB_02459 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOCDEKDB_02460 1.43e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
IOCDEKDB_02461 3.58e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IOCDEKDB_02462 9.54e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IOCDEKDB_02463 0.0 ypbR - - S - - - Dynamin family
IOCDEKDB_02464 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
IOCDEKDB_02465 1.08e-11 - - - - - - - -
IOCDEKDB_02466 2.26e-213 ypcP - - L - - - 5'3' exonuclease
IOCDEKDB_02467 2.59e-05 - - - - ko:K06429 - ko00000 -
IOCDEKDB_02468 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IOCDEKDB_02469 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IOCDEKDB_02470 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IOCDEKDB_02471 7.99e-41 ypeQ - - S - - - Zinc-finger
IOCDEKDB_02472 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
IOCDEKDB_02473 1.17e-22 degR - - - - - - -
IOCDEKDB_02474 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IOCDEKDB_02475 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IOCDEKDB_02476 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IOCDEKDB_02477 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IOCDEKDB_02478 2.42e-140 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IOCDEKDB_02479 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IOCDEKDB_02480 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IOCDEKDB_02481 2.78e-98 yphP - - S - - - Belongs to the UPF0403 family
IOCDEKDB_02482 8.04e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IOCDEKDB_02483 2.01e-147 ypjP - - S - - - YpjP-like protein
IOCDEKDB_02484 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IOCDEKDB_02485 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOCDEKDB_02486 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOCDEKDB_02487 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IOCDEKDB_02488 1.29e-232 yplP - - K - - - Transcriptional regulator
IOCDEKDB_02489 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IOCDEKDB_02490 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
IOCDEKDB_02491 6.15e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IOCDEKDB_02492 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IOCDEKDB_02493 5.59e-128 ypmS - - S - - - protein conserved in bacteria
IOCDEKDB_02494 8.69e-40 ypmT - - S - - - Uncharacterized ympT
IOCDEKDB_02495 7.03e-290 mepA - - V - - - MATE efflux family protein
IOCDEKDB_02496 4.14e-94 ypoP - - K - - - transcriptional
IOCDEKDB_02497 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOCDEKDB_02498 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IOCDEKDB_02499 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IOCDEKDB_02500 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IOCDEKDB_02501 9.37e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IOCDEKDB_02502 2.74e-60 cgeA - - - ko:K06319 - ko00000 -
IOCDEKDB_02503 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
IOCDEKDB_02504 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IOCDEKDB_02505 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IOCDEKDB_02507 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOCDEKDB_02509 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IOCDEKDB_02510 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IOCDEKDB_02511 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IOCDEKDB_02512 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IOCDEKDB_02513 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
IOCDEKDB_02514 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
IOCDEKDB_02515 7.44e-159 yodN - - - - - - -
IOCDEKDB_02517 2.11e-33 yozD - - S - - - YozD-like protein
IOCDEKDB_02518 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IOCDEKDB_02519 1.17e-71 yodL - - S - - - YodL-like
IOCDEKDB_02520 2.08e-12 - - - - - - - -
IOCDEKDB_02521 6.86e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IOCDEKDB_02522 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IOCDEKDB_02523 4.86e-41 yodI - - - - - - -
IOCDEKDB_02524 3.03e-166 yodH - - Q - - - Methyltransferase
IOCDEKDB_02525 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IOCDEKDB_02526 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOCDEKDB_02527 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
IOCDEKDB_02528 2.4e-60 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IOCDEKDB_02529 6.06e-136 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IOCDEKDB_02530 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IOCDEKDB_02531 0.0 yddG - - S - - - maturation of SSU-rRNA
IOCDEKDB_02532 6.19e-239 yddH - - M - - - Lysozyme-like
IOCDEKDB_02533 3.19e-111 yddI - - - - - - -
IOCDEKDB_02534 1.24e-86 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IOCDEKDB_02535 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
IOCDEKDB_02536 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_02538 9.39e-63 yhcM - - - - - - -
IOCDEKDB_02539 6e-104 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOCDEKDB_02540 1.01e-217 yhcP - - - - - - -
IOCDEKDB_02541 8.34e-128 yhcQ - - M - - - Spore coat protein
IOCDEKDB_02542 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IOCDEKDB_02543 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IOCDEKDB_02544 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IOCDEKDB_02545 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
IOCDEKDB_02546 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
IOCDEKDB_02547 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
IOCDEKDB_02548 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IOCDEKDB_02549 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOCDEKDB_02550 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IOCDEKDB_02551 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IOCDEKDB_02552 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOCDEKDB_02553 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IOCDEKDB_02554 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IOCDEKDB_02555 1.27e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02556 1.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_02557 2.7e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IOCDEKDB_02558 1.65e-51 yhdB - - S - - - YhdB-like protein
IOCDEKDB_02559 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
IOCDEKDB_02560 4.06e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IOCDEKDB_02561 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IOCDEKDB_02562 1.51e-306 ygxB - - M - - - Conserved TM helix
IOCDEKDB_02563 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IOCDEKDB_02564 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IOCDEKDB_02565 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IOCDEKDB_02566 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_02567 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IOCDEKDB_02568 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02569 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
IOCDEKDB_02570 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOCDEKDB_02571 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_02572 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_02573 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
IOCDEKDB_02574 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
IOCDEKDB_02575 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IOCDEKDB_02576 2.74e-243 yhdN - - C - - - Aldo keto reductase
IOCDEKDB_02577 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IOCDEKDB_02578 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IOCDEKDB_02579 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IOCDEKDB_02580 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IOCDEKDB_02581 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IOCDEKDB_02582 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IOCDEKDB_02583 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCDEKDB_02584 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCDEKDB_02585 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IOCDEKDB_02586 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
IOCDEKDB_02587 3.04e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IOCDEKDB_02588 8.05e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IOCDEKDB_02589 5.03e-194 nodB1 - - G - - - deacetylase
IOCDEKDB_02590 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IOCDEKDB_02591 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IOCDEKDB_02592 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
IOCDEKDB_02593 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_02594 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_02595 1.29e-140 yheG - - GM - - - NAD(P)H-binding
IOCDEKDB_02596 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
IOCDEKDB_02600 5.48e-110 - - - - - - - -
IOCDEKDB_02601 5.32e-26 - - - - - - - -
IOCDEKDB_02608 0.0 - - - D - - - Phage tail tape measure protein
IOCDEKDB_02610 2.31e-114 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_02611 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
IOCDEKDB_02612 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOCDEKDB_02614 6.7e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IOCDEKDB_02615 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IOCDEKDB_02616 1.97e-46 yuiB - - S - - - Putative membrane protein
IOCDEKDB_02617 2.69e-150 yuiC - - S - - - protein conserved in bacteria
IOCDEKDB_02618 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IOCDEKDB_02619 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IOCDEKDB_02620 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IOCDEKDB_02621 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IOCDEKDB_02622 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IOCDEKDB_02623 2.18e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
IOCDEKDB_02624 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_02625 1.22e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IOCDEKDB_02626 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IOCDEKDB_02627 1.82e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IOCDEKDB_02628 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_02629 8.23e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IOCDEKDB_02630 2.42e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IOCDEKDB_02631 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IOCDEKDB_02632 1.71e-291 yukF - - QT - - - Transcriptional regulator
IOCDEKDB_02633 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
IOCDEKDB_02634 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IOCDEKDB_02635 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IOCDEKDB_02636 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IOCDEKDB_02637 0.0 yueB - - S - - - type VII secretion protein EsaA
IOCDEKDB_02638 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
IOCDEKDB_02639 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02640 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IOCDEKDB_02641 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
IOCDEKDB_02642 1.35e-244 yueF - - S - - - transporter activity
IOCDEKDB_02643 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IOCDEKDB_02644 1.63e-52 yueH - - S - - - YueH-like protein
IOCDEKDB_02645 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
IOCDEKDB_02646 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IOCDEKDB_02647 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOCDEKDB_02648 1.97e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IOCDEKDB_02649 8.73e-09 yuzC - - - - - - -
IOCDEKDB_02650 6.29e-10 - - - S - - - DegQ (SacQ) family
IOCDEKDB_02651 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
IOCDEKDB_02653 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02654 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_02655 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IOCDEKDB_02656 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IOCDEKDB_02657 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOCDEKDB_02658 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOCDEKDB_02659 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOCDEKDB_02660 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOCDEKDB_02661 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IOCDEKDB_02662 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IOCDEKDB_02663 1.42e-21 - - - - - - - -
IOCDEKDB_02664 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
IOCDEKDB_02665 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IOCDEKDB_02666 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IOCDEKDB_02667 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02668 2.24e-251 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IOCDEKDB_02669 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IOCDEKDB_02670 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IOCDEKDB_02671 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
IOCDEKDB_02672 1.92e-97 yuxK - - S - - - protein conserved in bacteria
IOCDEKDB_02673 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IOCDEKDB_02674 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
IOCDEKDB_02676 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IOCDEKDB_02677 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IOCDEKDB_02678 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_02679 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IOCDEKDB_02680 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
IOCDEKDB_02681 9.89e-201 yugF - - I - - - Hydrolase
IOCDEKDB_02682 6.74e-112 alaR - - K - - - Transcriptional regulator
IOCDEKDB_02683 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IOCDEKDB_02684 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IOCDEKDB_02685 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IOCDEKDB_02686 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IOCDEKDB_02687 1.26e-287 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IOCDEKDB_02688 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IOCDEKDB_02690 4.22e-95 yugN - - S - - - YugN-like family
IOCDEKDB_02691 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IOCDEKDB_02692 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
IOCDEKDB_02693 2.16e-48 - - - - - - - -
IOCDEKDB_02694 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IOCDEKDB_02695 4.18e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IOCDEKDB_02696 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IOCDEKDB_02697 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
IOCDEKDB_02698 2.04e-47 - - - - - - - -
IOCDEKDB_02699 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IOCDEKDB_02700 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02701 4.17e-63 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02702 2.23e-199 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02703 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02704 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02705 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02706 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
IOCDEKDB_02707 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IOCDEKDB_02708 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IOCDEKDB_02709 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
IOCDEKDB_02710 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
IOCDEKDB_02711 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IOCDEKDB_02712 1.73e-252 yubA - - S - - - transporter activity
IOCDEKDB_02713 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IOCDEKDB_02715 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
IOCDEKDB_02716 0.0 yubD - - P - - - Major Facilitator Superfamily
IOCDEKDB_02717 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOCDEKDB_02718 3.31e-52 yubF - - S - - - yiaA/B two helix domain
IOCDEKDB_02719 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
IOCDEKDB_02720 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IOCDEKDB_02721 5.83e-118 yuaB - - - - - - -
IOCDEKDB_02722 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IOCDEKDB_02723 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IOCDEKDB_02724 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IOCDEKDB_02725 3.92e-135 yuaD - - - - - - -
IOCDEKDB_02726 6.53e-108 yuaE - - S - - - DinB superfamily
IOCDEKDB_02727 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IOCDEKDB_02728 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IOCDEKDB_02729 5.71e-121 - - - M - - - FR47-like protein
IOCDEKDB_02730 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IOCDEKDB_02744 4.3e-201 - - - S - - - damaged DNA binding
IOCDEKDB_02745 3.15e-36 - - - - - - - -
IOCDEKDB_02747 8.02e-30 - - - V - - - VanZ like family
IOCDEKDB_02752 1.4e-193 - - - - ko:K18640 - ko00000,ko04812 -
IOCDEKDB_02753 6.01e-61 - - - K - - - COG0457 FOG TPR repeat
IOCDEKDB_02755 0.000863 - - - K - - - Cro/C1-type HTH DNA-binding domain
IOCDEKDB_02759 2.47e-36 - - - S - - - Domain of unknown function (DUF5052)
IOCDEKDB_02762 1.64e-278 - - - M - - - domain protein
IOCDEKDB_02766 1.43e-138 - - - NU ko:K02283 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
IOCDEKDB_02767 4.6e-99 - - - - - - - -
IOCDEKDB_02768 4.26e-66 - - - - - - - -
IOCDEKDB_02769 3.88e-34 - - - - - - - -
IOCDEKDB_02775 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
IOCDEKDB_02776 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IOCDEKDB_02777 4.48e-35 ykzI - - - - - - -
IOCDEKDB_02778 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
IOCDEKDB_02779 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
IOCDEKDB_02780 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IOCDEKDB_02781 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IOCDEKDB_02782 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOCDEKDB_02783 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOCDEKDB_02784 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOCDEKDB_02785 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOCDEKDB_02786 6.37e-86 ykyA - - L - - - Putative cell-wall binding lipoprotein
IOCDEKDB_02787 6.41e-52 ykyA - - L - - - Putative cell-wall binding lipoprotein
IOCDEKDB_02788 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IOCDEKDB_02789 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOCDEKDB_02790 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
IOCDEKDB_02791 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
IOCDEKDB_02792 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOCDEKDB_02793 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IOCDEKDB_02794 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IOCDEKDB_02795 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IOCDEKDB_02796 4.22e-305 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IOCDEKDB_02797 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IOCDEKDB_02798 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IOCDEKDB_02799 1.09e-18 - - - S - - - Uncharacterized protein YkpC
IOCDEKDB_02800 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IOCDEKDB_02801 3.74e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOCDEKDB_02802 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOCDEKDB_02803 5.43e-52 ykoA - - - - - - -
IOCDEKDB_02804 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IOCDEKDB_02805 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IOCDEKDB_02806 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IOCDEKDB_02807 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_02808 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IOCDEKDB_02809 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_02810 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOCDEKDB_02811 1.31e-150 yknW - - S - - - Yip1 domain
IOCDEKDB_02812 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_02813 1.25e-95 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_02814 5.2e-260 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_02815 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IOCDEKDB_02816 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IOCDEKDB_02817 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IOCDEKDB_02818 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IOCDEKDB_02819 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOCDEKDB_02820 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IOCDEKDB_02821 9.46e-198 yknT - - - ko:K06437 - ko00000 -
IOCDEKDB_02824 0.000711 - - - - - - - -
IOCDEKDB_02825 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOCDEKDB_02826 5.71e-116 yhaK - - S - - - Putative zincin peptidase
IOCDEKDB_02827 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
IOCDEKDB_02828 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IOCDEKDB_02829 1.74e-54 yhaH - - S - - - YtxH-like protein
IOCDEKDB_02830 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
IOCDEKDB_02831 7.5e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IOCDEKDB_02832 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IOCDEKDB_02833 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IOCDEKDB_02834 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IOCDEKDB_02835 9.67e-160 ecsC - - S - - - EcsC protein family
IOCDEKDB_02836 8.54e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IOCDEKDB_02837 5.44e-312 yhfA - - C - - - membrane
IOCDEKDB_02838 1e-44 - - - C - - - Rubrerythrin
IOCDEKDB_02839 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IOCDEKDB_02840 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IOCDEKDB_02841 6.13e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IOCDEKDB_02842 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IOCDEKDB_02843 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IOCDEKDB_02844 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_02845 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IOCDEKDB_02846 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOCDEKDB_02847 2.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
IOCDEKDB_02848 1.55e-252 yhfE - - G - - - peptidase M42
IOCDEKDB_02849 1.79e-92 - - - S - - - ASCH
IOCDEKDB_02850 2.76e-288 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOCDEKDB_02851 9.84e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IOCDEKDB_02852 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IOCDEKDB_02853 2.13e-143 yhfK - - GM - - - NmrA-like family
IOCDEKDB_02854 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IOCDEKDB_02855 2.28e-84 yhfM - - - - - - -
IOCDEKDB_02856 9.64e-308 yhfN - - O - - - Peptidase M48
IOCDEKDB_02857 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IOCDEKDB_02858 1.47e-100 - - - K - - - acetyltransferase
IOCDEKDB_02859 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IOCDEKDB_02860 1.53e-220 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IOCDEKDB_02861 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IOCDEKDB_02862 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IOCDEKDB_02863 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IOCDEKDB_02864 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IOCDEKDB_02865 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IOCDEKDB_02866 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IOCDEKDB_02867 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IOCDEKDB_02868 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IOCDEKDB_02869 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_02870 9.84e-45 yhzC - - S - - - IDEAL
IOCDEKDB_02871 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IOCDEKDB_02872 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IOCDEKDB_02873 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
IOCDEKDB_02874 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOCDEKDB_02875 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
IOCDEKDB_02876 4.13e-78 yhjD - - - - - - -
IOCDEKDB_02877 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
IOCDEKDB_02878 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IOCDEKDB_02879 0.0 yhjG - - CH - - - FAD binding domain
IOCDEKDB_02880 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_02883 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IOCDEKDB_02884 2.69e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
IOCDEKDB_02885 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
IOCDEKDB_02886 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IOCDEKDB_02887 5.09e-238 yhjM - - K - - - Transcriptional regulator
IOCDEKDB_02888 4.83e-257 yhjN - - S ko:K07120 - ko00000 membrane
IOCDEKDB_02889 3.19e-266 - - - EGP - - - Transmembrane secretion effector
IOCDEKDB_02890 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
IOCDEKDB_02891 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IOCDEKDB_02892 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOCDEKDB_02893 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IOCDEKDB_02894 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IOCDEKDB_02896 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IOCDEKDB_02897 6.27e-67 yerC - - S - - - protein conserved in bacteria
IOCDEKDB_02898 1.25e-239 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IOCDEKDB_02899 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IOCDEKDB_02900 1.87e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
IOCDEKDB_02901 1.11e-95 - - - K - - - helix_turn_helix ASNC type
IOCDEKDB_02902 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IOCDEKDB_02903 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IOCDEKDB_02904 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOCDEKDB_02905 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IOCDEKDB_02906 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOCDEKDB_02907 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCDEKDB_02908 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCDEKDB_02909 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCDEKDB_02910 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IOCDEKDB_02911 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOCDEKDB_02912 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOCDEKDB_02913 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOCDEKDB_02914 3.13e-38 yebG - - S - - - NETI protein
IOCDEKDB_02915 2.66e-120 yebE - - S - - - UPF0316 protein
IOCDEKDB_02917 5.85e-165 yebC - - M - - - Membrane
IOCDEKDB_02918 1.33e-280 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IOCDEKDB_02920 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IOCDEKDB_02921 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IOCDEKDB_02922 2.63e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IOCDEKDB_02923 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IOCDEKDB_02924 4.82e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOCDEKDB_02925 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_02926 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IOCDEKDB_02927 8.17e-25 yeaA - - S - - - Protein of unknown function (DUF4003)
IOCDEKDB_02928 1.08e-188 yeaA - - S - - - Protein of unknown function (DUF4003)
IOCDEKDB_02929 1.46e-201 - - - I - - - Alpha/beta hydrolase family
IOCDEKDB_02930 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
IOCDEKDB_02932 7.89e-68 - - - M - - - ArpU family transcriptional regulator
IOCDEKDB_02934 1.12e-07 - - - S - - - YopX protein
IOCDEKDB_02936 6.17e-60 - - - S - - - dUTPase
IOCDEKDB_02942 2.78e-08 - - - - - - - -
IOCDEKDB_02945 1.76e-10 - - - - - - - -
IOCDEKDB_02946 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
IOCDEKDB_02947 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
IOCDEKDB_02950 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IOCDEKDB_02951 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
IOCDEKDB_02954 5.28e-79 - - - - - - - -
IOCDEKDB_02955 4.26e-43 - - - S - - - Phage integrase family
IOCDEKDB_02956 2.09e-81 - - - S - - - Phage integrase family
IOCDEKDB_02958 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IOCDEKDB_02959 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOCDEKDB_02960 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IOCDEKDB_02961 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IOCDEKDB_02962 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
IOCDEKDB_02963 4.9e-48 yvzC - - K - - - transcriptional
IOCDEKDB_02964 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IOCDEKDB_02965 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IOCDEKDB_02966 3.85e-72 yvaP - - K - - - transcriptional
IOCDEKDB_02967 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IOCDEKDB_02968 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IOCDEKDB_02969 1.13e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOCDEKDB_02970 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IOCDEKDB_02971 1.73e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOCDEKDB_02972 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IOCDEKDB_02973 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IOCDEKDB_02974 6.08e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IOCDEKDB_02975 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IOCDEKDB_02976 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IOCDEKDB_02977 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IOCDEKDB_02978 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IOCDEKDB_02979 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
IOCDEKDB_02980 2.66e-155 yvbI - - M - - - Membrane
IOCDEKDB_02981 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IOCDEKDB_02982 1.18e-97 yvbK - - K - - - acetyltransferase
IOCDEKDB_02983 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOCDEKDB_02984 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IOCDEKDB_02985 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOCDEKDB_02986 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IOCDEKDB_02987 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOCDEKDB_02988 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IOCDEKDB_02989 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_02990 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IOCDEKDB_02991 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IOCDEKDB_02992 1.99e-205 yvbU - - K - - - Transcriptional regulator
IOCDEKDB_02993 5.59e-198 yvbV - - EG - - - EamA-like transporter family
IOCDEKDB_02994 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IOCDEKDB_02995 2.7e-187 - - - S - - - Glycosyl hydrolase
IOCDEKDB_02996 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOCDEKDB_02997 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IOCDEKDB_02998 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IOCDEKDB_02999 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_03000 5.39e-252 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_03001 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IOCDEKDB_03002 5.7e-207 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IOCDEKDB_03003 8.25e-33 - 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 AAA domain
IOCDEKDB_03004 3.23e-178 - - - M - - - -acetyltransferase
IOCDEKDB_03005 1.15e-66 - - - S - - - ASCH
IOCDEKDB_03006 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
IOCDEKDB_03007 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
IOCDEKDB_03008 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IOCDEKDB_03009 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
IOCDEKDB_03010 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IOCDEKDB_03011 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IOCDEKDB_03012 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IOCDEKDB_03013 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_03014 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IOCDEKDB_03015 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IOCDEKDB_03016 4.25e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IOCDEKDB_03017 5.69e-44 yvfG - - S - - - YvfG protein
IOCDEKDB_03018 5.09e-239 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IOCDEKDB_03019 1.5e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IOCDEKDB_03020 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IOCDEKDB_03021 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOCDEKDB_03022 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_03023 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IOCDEKDB_03024 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IOCDEKDB_03025 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IOCDEKDB_03026 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IOCDEKDB_03027 1.19e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IOCDEKDB_03028 6.94e-199 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IOCDEKDB_03029 2.49e-278 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IOCDEKDB_03030 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IOCDEKDB_03031 1.6e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IOCDEKDB_03032 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IOCDEKDB_03033 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IOCDEKDB_03034 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IOCDEKDB_03036 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IOCDEKDB_03037 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
IOCDEKDB_03038 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
IOCDEKDB_03039 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IOCDEKDB_03040 2.17e-224 pbpE - - V - - - Beta-lactamase
IOCDEKDB_03041 3.77e-79 pbpE - - V - - - Beta-lactamase
IOCDEKDB_03042 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IOCDEKDB_03043 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IOCDEKDB_03044 0.0 ybeC - - E - - - amino acid
IOCDEKDB_03045 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
IOCDEKDB_03046 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IOCDEKDB_03047 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IOCDEKDB_03048 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
IOCDEKDB_03049 3.28e-29 - - - K - - - Helix-turn-helix
IOCDEKDB_03051 2.94e-166 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
IOCDEKDB_03052 1.27e-83 - - - - - - - -
IOCDEKDB_03054 7.35e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
IOCDEKDB_03055 2.24e-192 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IOCDEKDB_03056 1.85e-40 - - - S - - - BhlA holin family
IOCDEKDB_03058 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IOCDEKDB_03059 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IOCDEKDB_03060 9.55e-88 yqhY - - S - - - protein conserved in bacteria
IOCDEKDB_03061 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOCDEKDB_03062 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOCDEKDB_03063 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOCDEKDB_03064 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOCDEKDB_03065 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IOCDEKDB_03066 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOCDEKDB_03067 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IOCDEKDB_03068 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IOCDEKDB_03069 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IOCDEKDB_03070 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IOCDEKDB_03071 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IOCDEKDB_03073 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IOCDEKDB_03074 4.74e-37 - - - - - - - -
IOCDEKDB_03075 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IOCDEKDB_03076 3.02e-171 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IOCDEKDB_03077 6.65e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IOCDEKDB_03078 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IOCDEKDB_03079 7.33e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IOCDEKDB_03080 6.46e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IOCDEKDB_03081 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IOCDEKDB_03082 3.58e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IOCDEKDB_03083 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
IOCDEKDB_03084 0.0 bkdR - - KT - - - Transcriptional regulator
IOCDEKDB_03085 7.1e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IOCDEKDB_03086 7.81e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IOCDEKDB_03087 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IOCDEKDB_03088 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOCDEKDB_03089 1.58e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOCDEKDB_03090 8.08e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOCDEKDB_03091 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOCDEKDB_03092 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
IOCDEKDB_03093 8.11e-222 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_03094 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOCDEKDB_03095 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
IOCDEKDB_03096 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IOCDEKDB_03097 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IOCDEKDB_03098 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IOCDEKDB_03099 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IOCDEKDB_03100 6.92e-128 yqjB - - S - - - protein conserved in bacteria
IOCDEKDB_03102 7.75e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IOCDEKDB_03103 1.61e-30 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOCDEKDB_03104 7.25e-28 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOCDEKDB_03105 1.36e-265 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOCDEKDB_03106 3.04e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IOCDEKDB_03107 4.5e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
IOCDEKDB_03108 3.93e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOCDEKDB_03109 2.51e-32 yqzJ - - - - - - -
IOCDEKDB_03110 5.26e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOCDEKDB_03111 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOCDEKDB_03112 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOCDEKDB_03113 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOCDEKDB_03114 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IOCDEKDB_03115 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IOCDEKDB_03116 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IOCDEKDB_03117 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IOCDEKDB_03118 7.27e-55 - - - - - - - -
IOCDEKDB_03120 2.23e-17 - - - S - - - CGNR zinc finger
IOCDEKDB_03121 4.47e-103 - - - T - - - HPP family
IOCDEKDB_03122 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_03123 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_03124 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IOCDEKDB_03126 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IOCDEKDB_03127 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IOCDEKDB_03128 1.24e-22 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
IOCDEKDB_03132 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
IOCDEKDB_03133 1.71e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IOCDEKDB_03134 1.04e-122 gerD - - - ko:K06294 - ko00000 -
IOCDEKDB_03135 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IOCDEKDB_03136 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_03137 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
IOCDEKDB_03138 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
IOCDEKDB_03139 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IOCDEKDB_03140 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOCDEKDB_03141 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOCDEKDB_03142 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCDEKDB_03143 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCDEKDB_03144 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCDEKDB_03145 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IOCDEKDB_03146 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCDEKDB_03147 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOCDEKDB_03148 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOCDEKDB_03149 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IOCDEKDB_03150 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOCDEKDB_03151 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IOCDEKDB_03152 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOCDEKDB_03153 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOCDEKDB_03154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IOCDEKDB_03155 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IOCDEKDB_03156 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOCDEKDB_03157 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOCDEKDB_03158 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOCDEKDB_03159 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOCDEKDB_03160 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOCDEKDB_03161 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOCDEKDB_03162 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOCDEKDB_03163 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOCDEKDB_03164 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOCDEKDB_03165 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IOCDEKDB_03166 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOCDEKDB_03167 6.89e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOCDEKDB_03168 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOCDEKDB_03169 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOCDEKDB_03170 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOCDEKDB_03171 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOCDEKDB_03172 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IOCDEKDB_03173 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOCDEKDB_03174 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IOCDEKDB_03175 7.13e-228 ybaC - - S - - - Alpha/beta hydrolase family
IOCDEKDB_03176 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOCDEKDB_03177 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOCDEKDB_03178 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOCDEKDB_03179 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOCDEKDB_03180 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IOCDEKDB_03181 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCDEKDB_03182 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCDEKDB_03183 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IOCDEKDB_03184 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOCDEKDB_03185 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOCDEKDB_03186 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOCDEKDB_03187 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOCDEKDB_03188 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IOCDEKDB_03189 1.08e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOCDEKDB_03190 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IOCDEKDB_03191 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IOCDEKDB_03192 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOCDEKDB_03193 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOCDEKDB_03194 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IOCDEKDB_03195 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IOCDEKDB_03196 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOCDEKDB_03197 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IOCDEKDB_03198 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IOCDEKDB_03199 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IOCDEKDB_03200 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IOCDEKDB_03201 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOCDEKDB_03202 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IOCDEKDB_03203 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IOCDEKDB_03204 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IOCDEKDB_03205 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IOCDEKDB_03206 2.1e-71 ydfQ - - CO - - - Thioredoxin
IOCDEKDB_03207 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
IOCDEKDB_03208 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IOCDEKDB_03209 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IOCDEKDB_03210 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOCDEKDB_03211 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
IOCDEKDB_03212 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
IOCDEKDB_03213 2.2e-222 - - - S - - - Alpha/beta hydrolase family
IOCDEKDB_03214 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IOCDEKDB_03215 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_03216 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_03218 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IOCDEKDB_03219 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IOCDEKDB_03220 4.04e-149 ydfE - - S - - - Flavin reductase like domain
IOCDEKDB_03221 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
IOCDEKDB_03222 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_03223 9.99e-197 - - - EG - - - EamA-like transporter family
IOCDEKDB_03224 8.66e-186 - - - J - - - GNAT acetyltransferase
IOCDEKDB_03225 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IOCDEKDB_03226 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IOCDEKDB_03227 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IOCDEKDB_03228 4.66e-16 - - - K - - - HxlR-like helix-turn-helix
IOCDEKDB_03229 2.7e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
IOCDEKDB_03230 8.69e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IOCDEKDB_03231 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_03232 9.01e-195 ydeK - - EG - - - -transporter
IOCDEKDB_03233 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
IOCDEKDB_03234 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
IOCDEKDB_03235 2.51e-36 - - - S - - - SNARE associated Golgi protein
IOCDEKDB_03236 3.64e-142 - - - - - - - -
IOCDEKDB_03237 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
IOCDEKDB_03238 3.21e-70 ydeH - - - - - - -
IOCDEKDB_03239 1.16e-234 ydeG - - EGP - - - Major facilitator superfamily
IOCDEKDB_03240 3.74e-24 ydeG - - EGP - - - Major facilitator superfamily
IOCDEKDB_03241 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IOCDEKDB_03242 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
IOCDEKDB_03243 5.69e-105 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOCDEKDB_03244 4.71e-83 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOCDEKDB_03245 2.44e-210 - - - K - - - AraC-like ligand binding domain
IOCDEKDB_03246 5.97e-174 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IOCDEKDB_03247 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IOCDEKDB_03248 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IOCDEKDB_03249 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
IOCDEKDB_03253 2.98e-53 - - - - - - - -
IOCDEKDB_03254 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
IOCDEKDB_03255 1.35e-169 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOCDEKDB_03256 9.99e-59 - - - - - - - -
IOCDEKDB_03257 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
IOCDEKDB_03258 9.13e-135 ywqM - - K - - - Transcriptional regulator
IOCDEKDB_03259 4.46e-153 - - - E - - - amino acid
IOCDEKDB_03260 1.74e-95 - - - T - - - NACHT domain
IOCDEKDB_03261 3.75e-30 - - - - - - - -
IOCDEKDB_03262 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IOCDEKDB_03263 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IOCDEKDB_03264 6.16e-160 frp - - C - - - nitroreductase
IOCDEKDB_03265 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IOCDEKDB_03266 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IOCDEKDB_03267 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_03268 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
IOCDEKDB_03269 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
IOCDEKDB_03270 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IOCDEKDB_03271 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IOCDEKDB_03272 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IOCDEKDB_03273 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IOCDEKDB_03274 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
IOCDEKDB_03275 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
IOCDEKDB_03276 3.42e-157 yflK - - S - - - protein conserved in bacteria
IOCDEKDB_03277 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IOCDEKDB_03278 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IOCDEKDB_03279 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IOCDEKDB_03280 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IOCDEKDB_03281 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IOCDEKDB_03282 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IOCDEKDB_03283 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IOCDEKDB_03284 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IOCDEKDB_03285 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IOCDEKDB_03286 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IOCDEKDB_03287 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IOCDEKDB_03288 9.66e-92 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
IOCDEKDB_03290 2.17e-224 - - - L - - - Replication protein
IOCDEKDB_03292 1.81e-108 - - - K - - - Transcriptional regulator
IOCDEKDB_03293 2.99e-177 pre - - D - - - plasmid recombination enzyme
IOCDEKDB_03294 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
IOCDEKDB_03295 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IOCDEKDB_03296 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
IOCDEKDB_03298 4.19e-20 ynaF - - - - - - -
IOCDEKDB_03299 1.9e-102 - - - S - - - Domain of unknown function (DUF3885)
IOCDEKDB_03300 1.6e-08 - - - S - - - Domain of unknown function (DUF3885)
IOCDEKDB_03301 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IOCDEKDB_03302 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IOCDEKDB_03303 1.14e-90 - - - S - - - CAAX protease self-immunity
IOCDEKDB_03304 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
IOCDEKDB_03305 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IOCDEKDB_03306 0.0 yhaN - - L - - - AAA domain
IOCDEKDB_03307 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IOCDEKDB_03308 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IOCDEKDB_03309 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_03310 1.89e-35 - - - S - - - YhzD-like protein
IOCDEKDB_03311 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
IOCDEKDB_03313 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IOCDEKDB_03314 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IOCDEKDB_03315 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IOCDEKDB_03316 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IOCDEKDB_03317 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
IOCDEKDB_03318 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
IOCDEKDB_03319 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
IOCDEKDB_03320 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
IOCDEKDB_03321 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
IOCDEKDB_03322 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IOCDEKDB_03323 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
IOCDEKDB_03324 4.77e-116 ysxD - - - - - - -
IOCDEKDB_03325 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IOCDEKDB_03326 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
IOCDEKDB_03327 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IOCDEKDB_03328 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IOCDEKDB_03329 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IOCDEKDB_03330 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IOCDEKDB_03331 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IOCDEKDB_03332 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IOCDEKDB_03333 1.53e-35 - - - - - - - -
IOCDEKDB_03334 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOCDEKDB_03335 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IOCDEKDB_03336 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IOCDEKDB_03337 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IOCDEKDB_03338 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IOCDEKDB_03339 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IOCDEKDB_03340 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IOCDEKDB_03341 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IOCDEKDB_03342 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IOCDEKDB_03343 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IOCDEKDB_03344 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IOCDEKDB_03345 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IOCDEKDB_03346 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IOCDEKDB_03347 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IOCDEKDB_03348 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IOCDEKDB_03349 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IOCDEKDB_03350 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IOCDEKDB_03351 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOCDEKDB_03352 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IOCDEKDB_03353 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IOCDEKDB_03354 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IOCDEKDB_03355 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IOCDEKDB_03356 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IOCDEKDB_03357 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IOCDEKDB_03358 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IOCDEKDB_03359 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IOCDEKDB_03360 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IOCDEKDB_03361 3.51e-164 yebC - - K - - - transcriptional regulatory protein
IOCDEKDB_03362 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
IOCDEKDB_03363 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
IOCDEKDB_03365 5.47e-151 yrzF - - T - - - serine threonine protein kinase
IOCDEKDB_03366 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
IOCDEKDB_03367 0.0 csbX - - EGP - - - the major facilitator superfamily
IOCDEKDB_03368 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IOCDEKDB_03369 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOCDEKDB_03370 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOCDEKDB_03371 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
IOCDEKDB_03372 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IOCDEKDB_03373 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOCDEKDB_03374 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IOCDEKDB_03375 6.2e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
IOCDEKDB_03376 8.64e-145 yrbG - - S - - - membrane
IOCDEKDB_03377 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_03378 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
IOCDEKDB_03379 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IOCDEKDB_03380 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IOCDEKDB_03381 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IOCDEKDB_03382 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IOCDEKDB_03383 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOCDEKDB_03384 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOCDEKDB_03385 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOCDEKDB_03386 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IOCDEKDB_03388 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IOCDEKDB_03389 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IOCDEKDB_03390 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IOCDEKDB_03391 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IOCDEKDB_03392 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_03393 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IOCDEKDB_03394 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOCDEKDB_03395 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
IOCDEKDB_03396 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOCDEKDB_03397 1.38e-105 yrrD - - S - - - protein conserved in bacteria
IOCDEKDB_03398 8.4e-42 yrzR - - - - - - -
IOCDEKDB_03399 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
IOCDEKDB_03400 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_03401 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_03402 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IOCDEKDB_03403 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IOCDEKDB_03404 1.25e-241 yrrI - - S - - - AI-2E family transporter
IOCDEKDB_03405 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOCDEKDB_03406 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
IOCDEKDB_03407 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOCDEKDB_03408 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
IOCDEKDB_03409 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IOCDEKDB_03410 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IOCDEKDB_03411 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IOCDEKDB_03412 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IOCDEKDB_03413 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IOCDEKDB_03414 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOCDEKDB_03415 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IOCDEKDB_03416 1.65e-101 yrrS - - S - - - Protein of unknown function (DUF1510)
IOCDEKDB_03417 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
IOCDEKDB_03418 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IOCDEKDB_03419 1.14e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOCDEKDB_03420 3.91e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IOCDEKDB_03421 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IOCDEKDB_03422 5.71e-48 yrhC - - S - - - YrhC-like protein
IOCDEKDB_03423 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
IOCDEKDB_03424 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IOCDEKDB_03425 9.8e-313 yoeA - - V - - - MATE efflux family protein
IOCDEKDB_03426 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IOCDEKDB_03427 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IOCDEKDB_03428 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCDEKDB_03429 8.82e-37 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IOCDEKDB_03430 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IOCDEKDB_03431 8.25e-199 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
IOCDEKDB_03432 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
IOCDEKDB_03433 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IOCDEKDB_03434 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IOCDEKDB_03435 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IOCDEKDB_03436 2.81e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IOCDEKDB_03437 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IOCDEKDB_03438 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IOCDEKDB_03439 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IOCDEKDB_03440 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IOCDEKDB_03441 1.23e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
IOCDEKDB_03442 2.01e-134 yngC - - S - - - membrane-associated protein
IOCDEKDB_03443 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IOCDEKDB_03444 1.72e-103 yngA - - S - - - membrane
IOCDEKDB_03445 5.64e-35 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_03446 3.29e-308 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_03447 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
IOCDEKDB_03449 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IOCDEKDB_03450 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IOCDEKDB_03451 8.74e-75 ynfC - - - - - - -
IOCDEKDB_03452 1.82e-18 - - - - - - - -
IOCDEKDB_03453 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOCDEKDB_03454 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOCDEKDB_03455 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IOCDEKDB_03456 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOCDEKDB_03457 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
IOCDEKDB_03458 3.3e-71 yneQ - - - - - - -
IOCDEKDB_03459 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IOCDEKDB_03460 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IOCDEKDB_03462 9.26e-10 - - - S - - - Fur-regulated basic protein B
IOCDEKDB_03463 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IOCDEKDB_03464 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IOCDEKDB_03465 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IOCDEKDB_03466 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IOCDEKDB_03467 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
IOCDEKDB_03468 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
IOCDEKDB_03469 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IOCDEKDB_03470 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IOCDEKDB_03471 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IOCDEKDB_03472 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
IOCDEKDB_03473 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IOCDEKDB_03474 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IOCDEKDB_03475 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IOCDEKDB_03476 1.15e-43 ynzC - - S - - - UPF0291 protein
IOCDEKDB_03477 5.4e-143 yneB - - L - - - resolvase
IOCDEKDB_03478 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IOCDEKDB_03479 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOCDEKDB_03480 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IOCDEKDB_03481 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
IOCDEKDB_03482 1.09e-173 yndL - - S - - - Replication protein
IOCDEKDB_03485 0.0 yndJ - - S - - - YndJ-like protein
IOCDEKDB_03486 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
IOCDEKDB_03487 2.52e-196 yndG - - S - - - DoxX-like family
IOCDEKDB_03488 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
IOCDEKDB_03489 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IOCDEKDB_03490 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IOCDEKDB_03493 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IOCDEKDB_03495 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
IOCDEKDB_03497 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_03501 1.92e-47 - - - - - - - -
IOCDEKDB_03502 2.28e-25 - - - - - - - -
IOCDEKDB_03503 2.49e-07 - - - - - - - -
IOCDEKDB_03504 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IOCDEKDB_03505 2.43e-58 yjcN - - - - - - -
IOCDEKDB_03506 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IOCDEKDB_03507 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_03508 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IOCDEKDB_03509 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
IOCDEKDB_03510 7.74e-301 - - - I - - - Pfam Lipase (class 3)
IOCDEKDB_03511 1.82e-55 - - - - - - - -
IOCDEKDB_03513 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
IOCDEKDB_03518 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOCDEKDB_03519 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOCDEKDB_03520 3.12e-192 ypuA - - S - - - Secreted protein
IOCDEKDB_03521 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOCDEKDB_03522 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IOCDEKDB_03523 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
IOCDEKDB_03524 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IOCDEKDB_03525 1.21e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IOCDEKDB_03526 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IOCDEKDB_03527 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IOCDEKDB_03528 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IOCDEKDB_03529 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IOCDEKDB_03530 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IOCDEKDB_03531 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IOCDEKDB_03532 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IOCDEKDB_03533 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IOCDEKDB_03534 2.28e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOCDEKDB_03535 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IOCDEKDB_03536 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
IOCDEKDB_03537 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IOCDEKDB_03538 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IOCDEKDB_03539 1.47e-41 yqkK - - - - - - -
IOCDEKDB_03540 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IOCDEKDB_03541 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IOCDEKDB_03542 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IOCDEKDB_03543 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IOCDEKDB_03544 3.18e-77 ansR - - K - - - Transcriptional regulator
IOCDEKDB_03545 1.45e-280 yqxK - - L - - - DNA helicase
IOCDEKDB_03546 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IOCDEKDB_03547 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
IOCDEKDB_03548 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IOCDEKDB_03549 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
IOCDEKDB_03550 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IOCDEKDB_03551 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
IOCDEKDB_03552 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
IOCDEKDB_03553 6.8e-250 yqkA - - K - - - GrpB protein
IOCDEKDB_03554 2.63e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IOCDEKDB_03555 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IOCDEKDB_03556 1.87e-65 yqiX - - S - - - YolD-like protein
IOCDEKDB_03557 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOCDEKDB_03559 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
IOCDEKDB_03561 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_03562 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IOCDEKDB_03563 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IOCDEKDB_03564 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_03565 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IOCDEKDB_03566 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCDEKDB_03567 0.0 rocB - - E - - - arginine degradation protein
IOCDEKDB_03568 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IOCDEKDB_03569 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IOCDEKDB_03570 3.49e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IOCDEKDB_03571 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IOCDEKDB_03572 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IOCDEKDB_03573 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOCDEKDB_03574 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOCDEKDB_03575 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOCDEKDB_03576 6.97e-189 yerO - - K - - - Transcriptional regulator
IOCDEKDB_03577 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IOCDEKDB_03578 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IOCDEKDB_03579 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOCDEKDB_03580 1.14e-27 - - - - - - - -
IOCDEKDB_03581 0.0 - - - K - - - SIR2-like domain
IOCDEKDB_03583 1.41e-72 - - - S - - - Protein of unknown function, DUF600
IOCDEKDB_03584 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
IOCDEKDB_03585 1.25e-123 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IOCDEKDB_03586 1.06e-73 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
IOCDEKDB_03587 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
IOCDEKDB_03589 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
IOCDEKDB_03591 9.52e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_03592 1.55e-59 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IOCDEKDB_03593 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IOCDEKDB_03594 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IOCDEKDB_03595 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
IOCDEKDB_03596 6.29e-133 yesL - - S - - - Protein of unknown function, DUF624
IOCDEKDB_03597 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_03598 2.41e-199 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
IOCDEKDB_03599 7.99e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
IOCDEKDB_03600 1.17e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IOCDEKDB_03601 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IOCDEKDB_03602 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
IOCDEKDB_03603 0.0 yesS - - K - - - Transcriptional regulator
IOCDEKDB_03604 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
IOCDEKDB_03605 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
IOCDEKDB_03606 2.32e-144 - - - S - - - Protein of unknown function, DUF624
IOCDEKDB_03607 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IOCDEKDB_03608 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
IOCDEKDB_03609 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
IOCDEKDB_03610 2.73e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IOCDEKDB_03611 8.37e-153 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IOCDEKDB_03612 2.97e-193 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
IOCDEKDB_03613 2.25e-127 yetA - - - - - - -
IOCDEKDB_03614 5.02e-234 yetA - - - - - - -
IOCDEKDB_03615 1.54e-213 yetA - - - - - - -
IOCDEKDB_03616 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IOCDEKDB_03617 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
IOCDEKDB_03618 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IOCDEKDB_03619 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IOCDEKDB_03620 3.66e-157 yetF - - S - - - membrane
IOCDEKDB_03621 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IOCDEKDB_03622 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCDEKDB_03623 3.28e-44 - - - - - - - -
IOCDEKDB_03624 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOCDEKDB_03625 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
IOCDEKDB_03626 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IOCDEKDB_03627 1.3e-38 yetM - - CH - - - FAD binding domain
IOCDEKDB_03628 6.72e-171 - - - M - - - Membrane
IOCDEKDB_03629 2.09e-103 - - - - - - - -
IOCDEKDB_03630 7.6e-12 - - - S - - - Helix-turn-helix domain
IOCDEKDB_03631 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
IOCDEKDB_03632 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
IOCDEKDB_03633 5.33e-85 - - - - - - - -
IOCDEKDB_03634 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
IOCDEKDB_03636 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
IOCDEKDB_03637 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
IOCDEKDB_03638 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
IOCDEKDB_03640 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
IOCDEKDB_03641 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IOCDEKDB_03642 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IOCDEKDB_03643 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IOCDEKDB_03644 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IOCDEKDB_03645 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IOCDEKDB_03646 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_03647 6.31e-51 - - - - - - - -
IOCDEKDB_03648 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IOCDEKDB_03649 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
IOCDEKDB_03652 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
IOCDEKDB_03654 1.51e-18 cotW - - - ko:K06341 - ko00000 -
IOCDEKDB_03655 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IOCDEKDB_03656 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IOCDEKDB_03657 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IOCDEKDB_03658 2.09e-103 yjbX - - S - - - Spore coat protein
IOCDEKDB_03659 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IOCDEKDB_03660 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IOCDEKDB_03661 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IOCDEKDB_03662 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IOCDEKDB_03663 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
IOCDEKDB_03664 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IOCDEKDB_03665 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IOCDEKDB_03666 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IOCDEKDB_03667 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOCDEKDB_03668 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IOCDEKDB_03669 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IOCDEKDB_03670 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOCDEKDB_03671 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IOCDEKDB_03672 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
IOCDEKDB_03673 7.02e-128 yjbK - - S - - - protein conserved in bacteria
IOCDEKDB_03674 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOCDEKDB_03675 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IOCDEKDB_03676 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IOCDEKDB_03677 2.68e-28 - - - - - - - -
IOCDEKDB_03678 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IOCDEKDB_03679 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
IOCDEKDB_03680 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IOCDEKDB_03681 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
IOCDEKDB_03682 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOCDEKDB_03683 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCDEKDB_03684 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
IOCDEKDB_03685 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_03686 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_03687 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_03688 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_03689 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IOCDEKDB_03690 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IOCDEKDB_03691 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
IOCDEKDB_03692 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_03693 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IOCDEKDB_03694 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IOCDEKDB_03695 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_03696 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IOCDEKDB_03697 3.86e-192 yjaZ - - O - - - Zn-dependent protease
IOCDEKDB_03698 5.08e-301 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IOCDEKDB_03699 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOCDEKDB_03700 3.48e-33 yjzB - - - - - - -
IOCDEKDB_03701 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IOCDEKDB_03702 3.04e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IOCDEKDB_03703 5.2e-132 yjaV - - - - - - -
IOCDEKDB_03704 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
IOCDEKDB_03705 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
IOCDEKDB_03706 2.51e-39 yjzC - - S - - - YjzC-like protein
IOCDEKDB_03707 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IOCDEKDB_03708 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
IOCDEKDB_03709 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
IOCDEKDB_03710 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IOCDEKDB_03711 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IOCDEKDB_03712 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_03713 4.79e-160 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_03714 1.98e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_03715 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IOCDEKDB_03716 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IOCDEKDB_03717 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IOCDEKDB_03718 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOCDEKDB_03719 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IOCDEKDB_03720 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IOCDEKDB_03721 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
IOCDEKDB_03722 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IOCDEKDB_03723 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
IOCDEKDB_03724 2.19e-153 yxaC - - M - - - effector of murein hydrolase
IOCDEKDB_03725 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IOCDEKDB_03726 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_03727 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_03728 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IOCDEKDB_03729 7.7e-248 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
IOCDEKDB_03731 1.49e-207 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
IOCDEKDB_03732 4.82e-294 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOCDEKDB_03734 3.26e-72 - - - L - - - transposase activity
IOCDEKDB_03735 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
IOCDEKDB_03736 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IOCDEKDB_03737 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IOCDEKDB_03738 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IOCDEKDB_03739 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOCDEKDB_03740 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOCDEKDB_03741 4.53e-239 ysoA - - H - - - Tetratricopeptide repeat
IOCDEKDB_03742 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOCDEKDB_03743 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IOCDEKDB_03744 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IOCDEKDB_03745 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IOCDEKDB_03746 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IOCDEKDB_03747 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IOCDEKDB_03748 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IOCDEKDB_03750 1.38e-84 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IOCDEKDB_03751 4.77e-181 ysnF - - S - - - protein conserved in bacteria
IOCDEKDB_03754 4.48e-214 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
IOCDEKDB_03755 4.33e-50 - - - S - - - domain, Protein
IOCDEKDB_03757 1.47e-47 - - - - - - - -
IOCDEKDB_03758 5.71e-216 - - - S - - - AAA-like domain
IOCDEKDB_03760 9.35e-69 yddH - - M - - - Lysozyme-like
IOCDEKDB_03764 1.86e-111 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
IOCDEKDB_03766 2.51e-49 - - - L - - - Protein of unknown function (DUF3991)
IOCDEKDB_03770 2.5e-06 rok - - S - - - Repressor of ComK
IOCDEKDB_03772 4.64e-65 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOCDEKDB_03775 2.28e-53 - - - L - - - Site-specific recombinase, phage integrase family
IOCDEKDB_03781 1.32e-151 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
IOCDEKDB_03784 3.45e-48 nucH 3.1.31.1 - L ko:K01174 - ko00000,ko01000 COG1525 Micrococcal nuclease (thermonuclease) homologs
IOCDEKDB_03787 8.73e-109 - - - L - - - Domain of unknown function (DUF1738)
IOCDEKDB_03788 5.94e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_03789 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
IOCDEKDB_03790 5.04e-109 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOCDEKDB_03791 1.03e-66 yfkI - - S - - - gas vesicle protein
IOCDEKDB_03792 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IOCDEKDB_03793 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IOCDEKDB_03794 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IOCDEKDB_03795 3.69e-189 yfkD - - S - - - YfkD-like protein
IOCDEKDB_03796 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
IOCDEKDB_03797 1.76e-283 yfkA - - S - - - YfkB-like domain
IOCDEKDB_03798 3.26e-36 yfjT - - - - - - -
IOCDEKDB_03799 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IOCDEKDB_03800 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IOCDEKDB_03801 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IOCDEKDB_03802 5.57e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IOCDEKDB_03803 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOCDEKDB_03804 3.04e-59 - - - S - - - YfzA-like protein
IOCDEKDB_03805 7.83e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOCDEKDB_03806 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
IOCDEKDB_03808 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IOCDEKDB_03809 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IOCDEKDB_03810 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOCDEKDB_03811 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IOCDEKDB_03812 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IOCDEKDB_03813 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IOCDEKDB_03814 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
IOCDEKDB_03815 1e-105 - - - S - - - Family of unknown function (DUF5381)
IOCDEKDB_03816 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
IOCDEKDB_03817 1.02e-184 yfjC - - - - - - -
IOCDEKDB_03818 1.94e-270 yfjB - - - - - - -
IOCDEKDB_03819 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
IOCDEKDB_03820 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IOCDEKDB_03821 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IOCDEKDB_03822 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IOCDEKDB_03823 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
IOCDEKDB_03824 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IOCDEKDB_03825 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IOCDEKDB_03826 4.74e-83 yfiD3 - - S - - - DoxX
IOCDEKDB_03827 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IOCDEKDB_03828 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
IOCDEKDB_03829 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_03830 5.47e-234 - - - G - - - Xylose isomerase
IOCDEKDB_03831 2.46e-32 - - - S - - - Oxidoreductase
IOCDEKDB_03832 4.36e-249 - - - S - - - Oxidoreductase
IOCDEKDB_03834 1.7e-272 baeS - - T - - - Histidine kinase
IOCDEKDB_03835 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
IOCDEKDB_03836 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_03837 1.15e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_03838 6.08e-256 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IOCDEKDB_03839 1.38e-121 padR - - K - - - transcriptional
IOCDEKDB_03840 5.67e-121 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IOCDEKDB_03841 6.57e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IOCDEKDB_03842 1.57e-136 yfiR - - K - - - Transcriptional regulator
IOCDEKDB_03843 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
IOCDEKDB_03844 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IOCDEKDB_03845 1.74e-131 yfiU - - EGP - - - the major facilitator superfamily
IOCDEKDB_03846 7.36e-215 yfiU - - EGP - - - the major facilitator superfamily
IOCDEKDB_03847 2.11e-103 yfiV - - K - - - transcriptional
IOCDEKDB_03848 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOCDEKDB_03849 3.15e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IOCDEKDB_03850 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_03851 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCDEKDB_03852 3.1e-214 yfhB - - S - - - PhzF family
IOCDEKDB_03853 4.76e-137 yfhC - - C - - - nitroreductase
IOCDEKDB_03854 3.61e-34 yfhD - - S - - - YfhD-like protein
IOCDEKDB_03856 1.88e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IOCDEKDB_03857 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IOCDEKDB_03858 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IOCDEKDB_03860 2.45e-268 yfhI - - EGP - - - -transporter
IOCDEKDB_03861 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
IOCDEKDB_03862 8.95e-60 yfhJ - - S - - - WVELL protein
IOCDEKDB_03863 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
IOCDEKDB_03864 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
IOCDEKDB_03865 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
IOCDEKDB_03866 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IOCDEKDB_03867 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IOCDEKDB_03868 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IOCDEKDB_03869 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IOCDEKDB_03870 1.73e-48 yfhS - - - - - - -
IOCDEKDB_03871 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IOCDEKDB_03872 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IOCDEKDB_03873 2.01e-49 ygaB - - S - - - YgaB-like protein
IOCDEKDB_03874 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IOCDEKDB_03875 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IOCDEKDB_03876 1.08e-237 ygaE - - S - - - Membrane
IOCDEKDB_03877 1.89e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IOCDEKDB_03878 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IOCDEKDB_03879 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IOCDEKDB_03880 5.46e-74 ygzB - - S - - - UPF0295 protein
IOCDEKDB_03881 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
IOCDEKDB_03882 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IOCDEKDB_03883 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IOCDEKDB_03884 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IOCDEKDB_03885 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IOCDEKDB_03887 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IOCDEKDB_03888 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IOCDEKDB_03889 7.68e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IOCDEKDB_03890 2.91e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IOCDEKDB_03891 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IOCDEKDB_03893 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_03896 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
IOCDEKDB_03900 1.23e-151 - - - K - - - Transcriptional regulator
IOCDEKDB_03901 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IOCDEKDB_03902 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IOCDEKDB_03903 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_03904 1.24e-198 degV - - S - - - protein conserved in bacteria
IOCDEKDB_03905 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IOCDEKDB_03906 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IOCDEKDB_03907 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IOCDEKDB_03908 3.05e-95 yvyF - - S - - - flagellar protein
IOCDEKDB_03909 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IOCDEKDB_03910 7.06e-102 yvyG - - NOU - - - FlgN protein
IOCDEKDB_03911 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IOCDEKDB_03912 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IOCDEKDB_03913 6.92e-92 yviE - - - - - - -
IOCDEKDB_03914 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IOCDEKDB_03915 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IOCDEKDB_03916 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOCDEKDB_03917 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
IOCDEKDB_03918 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IOCDEKDB_03919 1.48e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IOCDEKDB_03920 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IOCDEKDB_03921 2.46e-67 - - - - - - - -
IOCDEKDB_03922 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOCDEKDB_03923 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOCDEKDB_03924 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOCDEKDB_03925 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IOCDEKDB_03926 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IOCDEKDB_03927 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IOCDEKDB_03928 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IOCDEKDB_03929 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IOCDEKDB_03930 1.38e-73 swrA - - S - - - Swarming motility protein
IOCDEKDB_03931 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IOCDEKDB_03932 3.03e-295 yvkA - - P - - - -transporter
IOCDEKDB_03933 1.43e-131 yvkB - - K - - - Transcriptional regulator
IOCDEKDB_03934 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IOCDEKDB_03935 2.54e-42 csbA - - S - - - protein conserved in bacteria
IOCDEKDB_03936 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOCDEKDB_03937 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOCDEKDB_03938 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IOCDEKDB_03939 2.25e-45 yvkN - - - - - - -
IOCDEKDB_03940 8.09e-65 yvlA - - - - - - -
IOCDEKDB_03941 5.54e-219 yvlB - - S - - - Putative adhesin
IOCDEKDB_03942 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IOCDEKDB_03943 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IOCDEKDB_03946 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IOCDEKDB_03947 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IOCDEKDB_03948 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IOCDEKDB_03949 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IOCDEKDB_03950 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOCDEKDB_03951 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IOCDEKDB_03952 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOCDEKDB_03953 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOCDEKDB_03954 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IOCDEKDB_03955 8.36e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IOCDEKDB_03956 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IOCDEKDB_03957 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IOCDEKDB_03958 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOCDEKDB_03959 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOCDEKDB_03961 1.17e-148 - - - - - - - -
IOCDEKDB_03962 5.53e-175 - - - - - - - -
IOCDEKDB_03963 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IOCDEKDB_03964 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IOCDEKDB_03965 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IOCDEKDB_03966 1.22e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IOCDEKDB_03967 3.64e-59 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IOCDEKDB_03968 8.87e-76 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IOCDEKDB_03969 1.42e-225 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOCDEKDB_03970 1.48e-172 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IOCDEKDB_03971 5.98e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IOCDEKDB_03972 1.53e-245 - - - S - - - Ion transport 2 domain protein
IOCDEKDB_03973 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_03974 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IOCDEKDB_03975 1.79e-84 ydjM - - M - - - Lytic transglycolase
IOCDEKDB_03976 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IOCDEKDB_03979 5.37e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
IOCDEKDB_03981 1.92e-145 - - - S - - - Helix-turn-helix domain
IOCDEKDB_03982 6.09e-40 - - - L - - - Phage integrase family
IOCDEKDB_03984 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOCDEKDB_03985 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IOCDEKDB_03986 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IOCDEKDB_03987 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
IOCDEKDB_03988 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
IOCDEKDB_03989 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
IOCDEKDB_03990 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
IOCDEKDB_03991 2.83e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
IOCDEKDB_03992 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
IOCDEKDB_03993 6.55e-223 yvdE - - K - - - Transcriptional regulator
IOCDEKDB_03994 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IOCDEKDB_03995 1.27e-39 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IOCDEKDB_03996 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IOCDEKDB_03997 1.07e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IOCDEKDB_03998 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCDEKDB_03999 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IOCDEKDB_04000 1.05e-179 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IOCDEKDB_04001 1.38e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
IOCDEKDB_04002 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IOCDEKDB_04003 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IOCDEKDB_04004 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IOCDEKDB_04005 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IOCDEKDB_04006 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IOCDEKDB_04007 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IOCDEKDB_04008 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IOCDEKDB_04009 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOCDEKDB_04010 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IOCDEKDB_04011 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IOCDEKDB_04012 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IOCDEKDB_04014 0.0 - - - - - - - -
IOCDEKDB_04015 1.29e-111 - - - - - - - -
IOCDEKDB_04016 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IOCDEKDB_04017 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IOCDEKDB_04018 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IOCDEKDB_04019 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IOCDEKDB_04020 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IOCDEKDB_04021 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IOCDEKDB_04022 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IOCDEKDB_04023 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IOCDEKDB_04024 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
IOCDEKDB_04025 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
IOCDEKDB_04026 5.64e-32 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IOCDEKDB_04027 9.06e-65 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IOCDEKDB_04028 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IOCDEKDB_04029 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
IOCDEKDB_04030 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOCDEKDB_04031 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOCDEKDB_04032 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IOCDEKDB_04033 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOCDEKDB_04034 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IOCDEKDB_04035 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IOCDEKDB_04041 4.34e-30 - - - K - - - Sigma-70, region 4
IOCDEKDB_04044 2.14e-51 - - - - - - - -
IOCDEKDB_04047 3.04e-11 - - - - - - - -
IOCDEKDB_04048 1.12e-86 - - - L - - - Phage integrase family
IOCDEKDB_04049 5.35e-169 - - - S - - - TIGRFAM Phage uncharacterised protein, C-terminal
IOCDEKDB_04050 7.57e-31 - - - S - - - Helix-turn-helix of insertion element transposase
IOCDEKDB_04051 1.27e-192 - - - - - - - -
IOCDEKDB_04052 2.45e-106 - - - S - - - Phage minor capsid protein 2
IOCDEKDB_04053 4.51e-08 - - - S - - - Domain of unknown function (DUF4355)
IOCDEKDB_04054 1.74e-102 - - - - - - - -
IOCDEKDB_04056 2.82e-34 - - - - - - - -
IOCDEKDB_04057 4.04e-22 - - - - - - - -
IOCDEKDB_04058 7.61e-40 - - - - - - - -
IOCDEKDB_04059 1.56e-65 - - - N - - - domain, Protein
IOCDEKDB_04060 7.39e-33 - - - - - - - -
IOCDEKDB_04062 9.06e-135 - - - D - - - phage tail tape measure protein
IOCDEKDB_04063 1.37e-67 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IOCDEKDB_04064 7.54e-92 - - - L - - - Prophage endopeptidase tail
IOCDEKDB_04065 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOCDEKDB_04066 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IOCDEKDB_04067 4.84e-85 - - - S - - - damaged DNA binding
IOCDEKDB_04068 2.34e-14 - - - S - - - YolD-like protein
IOCDEKDB_04071 2.06e-125 - - - J - - - Acetyltransferase (GNAT) domain
IOCDEKDB_04072 5.44e-124 yokK - - S - - - SMI1 / KNR4 family
IOCDEKDB_04073 5.49e-102 - - - S - - - SMI1-KNR4 cell-wall
IOCDEKDB_04074 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IOCDEKDB_04075 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOCDEKDB_04076 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
IOCDEKDB_04077 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
IOCDEKDB_04078 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IOCDEKDB_04079 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IOCDEKDB_04080 1.98e-178 - - - J - - - FR47-like protein
IOCDEKDB_04081 7.27e-126 yobS - - K - - - Transcriptional regulator
IOCDEKDB_04082 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IOCDEKDB_04083 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
IOCDEKDB_04084 2.76e-220 yobV - - K - - - WYL domain
IOCDEKDB_04085 2.58e-121 yobW - - - - - - -
IOCDEKDB_04086 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IOCDEKDB_04087 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IOCDEKDB_04088 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
IOCDEKDB_04089 9.86e-88 - - - - - - - -
IOCDEKDB_04090 8.68e-67 - - - - - - - -
IOCDEKDB_04091 1.08e-121 yocC - - - - - - -
IOCDEKDB_04092 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IOCDEKDB_04093 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IOCDEKDB_04094 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IOCDEKDB_04095 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IOCDEKDB_04097 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
IOCDEKDB_04098 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IOCDEKDB_04099 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IOCDEKDB_04100 2.87e-107 yocK - - T - - - general stress protein
IOCDEKDB_04101 4.29e-70 yocL - - - - - - -
IOCDEKDB_04102 3.93e-41 - - - - - - - -
IOCDEKDB_04103 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IOCDEKDB_04104 2.94e-55 yozN - - - - - - -
IOCDEKDB_04105 1.83e-49 yocN - - - - - - -
IOCDEKDB_04106 2.17e-74 yozO - - S - - - Bacterial PH domain
IOCDEKDB_04107 1.91e-42 yozC - - - - - - -
IOCDEKDB_04108 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IOCDEKDB_04109 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IOCDEKDB_04110 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IOCDEKDB_04111 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IOCDEKDB_04112 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
IOCDEKDB_04113 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IOCDEKDB_04114 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IOCDEKDB_04115 0.0 yojO - - P - - - Von Willebrand factor
IOCDEKDB_04116 8.98e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IOCDEKDB_04117 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IOCDEKDB_04118 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IOCDEKDB_04119 3.79e-292 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IOCDEKDB_04120 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOCDEKDB_04122 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IOCDEKDB_04123 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IOCDEKDB_04124 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IOCDEKDB_04125 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
IOCDEKDB_04126 1.85e-58 - - - - - - - -
IOCDEKDB_04127 1.64e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IOCDEKDB_04128 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IOCDEKDB_04129 5.59e-14 - - - - - - - -
IOCDEKDB_04130 1.26e-168 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IOCDEKDB_04131 7.01e-96 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IOCDEKDB_04132 2.3e-83 iolK - - S - - - tautomerase
IOCDEKDB_04133 2.63e-73 yodB - - K - - - transcriptional
IOCDEKDB_04134 6.44e-139 yodC - - C - - - nitroreductase
IOCDEKDB_04135 7.47e-233 yaaC - - S - - - YaaC-like Protein
IOCDEKDB_04136 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IOCDEKDB_04137 1.24e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IOCDEKDB_04138 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IOCDEKDB_04139 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IOCDEKDB_04140 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOCDEKDB_04142 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IOCDEKDB_04143 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IOCDEKDB_04144 1.48e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IOCDEKDB_04145 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IOCDEKDB_04146 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOCDEKDB_04147 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOCDEKDB_04148 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOCDEKDB_04149 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOCDEKDB_04150 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
IOCDEKDB_04151 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IOCDEKDB_04152 3.65e-81 ynaC - - - - - - -
IOCDEKDB_04153 9.3e-51 ynaC - - - - - - -
IOCDEKDB_04154 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
IOCDEKDB_04155 4.13e-51 - - - - - - - -
IOCDEKDB_04156 1.46e-105 - - - - - - - -
IOCDEKDB_04158 1.68e-13 - - - - - - - -
IOCDEKDB_04159 3.12e-09 - - - - - - - -
IOCDEKDB_04160 6.2e-28 - - - S - - - Domain of unknown function (DUF4917)
IOCDEKDB_04161 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOCDEKDB_04162 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IOCDEKDB_04163 4.08e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IOCDEKDB_04164 3.19e-41 xhlB - - S - - - SPP1 phage holin
IOCDEKDB_04165 4.44e-38 bhlA - - S - - - BhlA holin family
IOCDEKDB_04168 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IOCDEKDB_04169 2.78e-272 xylR - - GK - - - ROK family
IOCDEKDB_04170 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IOCDEKDB_04171 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IOCDEKDB_04172 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IOCDEKDB_04173 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCDEKDB_04174 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOCDEKDB_04176 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IOCDEKDB_04177 7.54e-22 - - - - - - - -
IOCDEKDB_04180 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOCDEKDB_04182 2.43e-162 - - - S - - - Domain of unknown function, YrpD
IOCDEKDB_04185 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
IOCDEKDB_04186 8.92e-96 - - - - - - - -
IOCDEKDB_04192 0.00063 - - - L - - - Pfam:DUF955
IOCDEKDB_04195 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
IOCDEKDB_04205 1.07e-25 - - - - - - - -
IOCDEKDB_04206 0.0 - - - - - - - -
IOCDEKDB_04207 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IOCDEKDB_04209 0.0 - - - D - - - Phage tail tape measure protein
IOCDEKDB_04212 1.46e-33 - - - - - - - -
IOCDEKDB_04214 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IOCDEKDB_04215 8.17e-38 - - - S - - - Phage head-tail joining protein
IOCDEKDB_04217 5.45e-13 - - - - - - - -
IOCDEKDB_04218 1.64e-161 - - - S - - - capsid protein
IOCDEKDB_04219 3.96e-94 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
IOCDEKDB_04220 3.12e-215 - - - S - - - portal protein
IOCDEKDB_04222 0.0 terL - - S - - - Terminase
IOCDEKDB_04223 1.34e-77 - - - L - - - Terminase, small subunit
IOCDEKDB_04227 2.62e-78 - - - - - - - -
IOCDEKDB_04229 1.06e-106 - - - - - - - -
IOCDEKDB_04230 3.14e-121 - - - S - - - nuclease activity
IOCDEKDB_04231 3.9e-85 - - - - - - - -
IOCDEKDB_04232 0.0 - - - S - - - hydrolase activity
IOCDEKDB_04233 3.5e-97 - - - S - - - Protein of unknown function (DUF669)
IOCDEKDB_04234 1.15e-07 - - - - - - - -
IOCDEKDB_04235 6.48e-216 - - - S - - - AAA domain
IOCDEKDB_04236 5.36e-120 - - - S - - - DNA protection
IOCDEKDB_04238 3.42e-26 - - - S - - - Uncharacterized protein YqaH
IOCDEKDB_04240 4.75e-28 - - - - - - - -
IOCDEKDB_04241 7.74e-65 - - - S - - - Phage antirepressor protein KilAC domain
IOCDEKDB_04243 3.93e-09 - - - K - - - Helix-turn-helix
IOCDEKDB_04244 1.4e-59 - - - CE - - - IrrE N-terminal-like domain
IOCDEKDB_04245 4.35e-171 - - - L - - - Belongs to the 'phage' integrase family
IOCDEKDB_04246 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IOCDEKDB_04247 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IOCDEKDB_04248 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IOCDEKDB_04249 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOCDEKDB_04250 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IOCDEKDB_04251 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_04252 2.24e-141 - - - - - - - -
IOCDEKDB_04253 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOCDEKDB_04254 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOCDEKDB_04255 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IOCDEKDB_04256 1.2e-30 ymzA - - - - - - -
IOCDEKDB_04257 1.63e-31 - - - - - - - -
IOCDEKDB_04258 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IOCDEKDB_04259 5.61e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOCDEKDB_04260 3.13e-75 ymaF - - S - - - YmaF family
IOCDEKDB_04262 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IOCDEKDB_04263 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
IOCDEKDB_04264 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IOCDEKDB_04265 8e-163 ymaC - - S - - - Replication protein
IOCDEKDB_04267 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IOCDEKDB_04268 1.04e-204 - - - S - - - Metallo-beta-lactamase superfamily
IOCDEKDB_04269 8.03e-81 ymzB - - - - - - -
IOCDEKDB_04270 1.02e-134 pksA - - K - - - Transcriptional regulator
IOCDEKDB_04271 9.3e-126 ymcC - - S - - - Membrane
IOCDEKDB_04272 2.23e-90 - - - S - - - Regulatory protein YrvL
IOCDEKDB_04273 2.64e-42 - - - - - - - -
IOCDEKDB_04274 0.0 - - - V - - - Abi-like protein
IOCDEKDB_04275 0.0 - - - L - - - Superfamily I DNA and RNA helicases
IOCDEKDB_04276 0.0 - - - L - - - AAA ATPase domain
IOCDEKDB_04277 6.88e-84 - - - S - - - HTH-like domain
IOCDEKDB_04278 1.51e-174 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
IOCDEKDB_04279 1.59e-65 - - - L - - - Transposase
IOCDEKDB_04280 1.8e-87 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IOCDEKDB_04281 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IOCDEKDB_04282 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IOCDEKDB_04288 1.27e-07 - - - S - - - peptidoglycan catabolic process
IOCDEKDB_04289 1.14e-20 - - - S - - - peptidoglycan catabolic process
IOCDEKDB_04290 2.45e-34 - - - K - - - Helix-turn-helix domain
IOCDEKDB_04291 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
IOCDEKDB_04292 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IOCDEKDB_04293 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IOCDEKDB_04294 0.0 lytB - - D - - - Stage II sporulation protein
IOCDEKDB_04295 1.39e-15 - - - - - - - -
IOCDEKDB_04296 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IOCDEKDB_04297 1.24e-299 yoaB - - EGP - - - the major facilitator superfamily
IOCDEKDB_04298 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IOCDEKDB_04299 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IOCDEKDB_04300 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_04301 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
IOCDEKDB_04302 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IOCDEKDB_04303 7.05e-172 yoxB - - - - - - -
IOCDEKDB_04304 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
IOCDEKDB_04305 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCDEKDB_04306 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IOCDEKDB_04307 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCDEKDB_04308 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCDEKDB_04309 5.87e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOCDEKDB_04310 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_04311 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IOCDEKDB_04312 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IOCDEKDB_04313 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IOCDEKDB_04314 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IOCDEKDB_04315 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IOCDEKDB_04316 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
IOCDEKDB_04317 1.14e-124 - - - L - - - Integrase
IOCDEKDB_04319 2.94e-236 - - - S - - - Domain of unknown function (DUF2479)
IOCDEKDB_04320 0.0 - - - - - - - -
IOCDEKDB_04321 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
IOCDEKDB_04322 1.96e-141 - - - S - - - Phage tail protein
IOCDEKDB_04323 0.0 - - - S - - - peptidoglycan catabolic process
IOCDEKDB_04324 4.09e-16 - - - - - - - -
IOCDEKDB_04325 1.58e-36 - - - - - - - -
IOCDEKDB_04326 9.75e-79 - - - - - - - -
IOCDEKDB_04327 1.42e-40 - - - - - - - -
IOCDEKDB_04328 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
IOCDEKDB_04329 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
IOCDEKDB_04330 1.23e-39 - - - S - - - peptidoglycan catabolic process
IOCDEKDB_04331 8.02e-09 - - - S - - - peptidoglycan catabolic process
IOCDEKDB_04332 3.43e-227 - - - S - - - capsid protein
IOCDEKDB_04333 9.36e-135 - - - S - - - peptidase activity
IOCDEKDB_04334 4.77e-273 - - - S - - - Phage portal protein
IOCDEKDB_04335 2.58e-14 - - - - - - - -
IOCDEKDB_04336 1.37e-277 - - - S - - - Phage Terminase
IOCDEKDB_04337 1e-89 - - - S - - - Phage terminase, small subunit
IOCDEKDB_04338 2.63e-11 - - - - - - - -
IOCDEKDB_04347 1.78e-53 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IOCDEKDB_04349 4.82e-69 ynaF - - - - - - -
IOCDEKDB_04351 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IOCDEKDB_04353 0.0 - - - V - - - Beta-lactamase
IOCDEKDB_04356 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
IOCDEKDB_04357 2.14e-17 - - - Q - - - methyltransferase
IOCDEKDB_04359 3.99e-53 - - - - - - - -
IOCDEKDB_04361 1.07e-57 - - - S - - - transposition, DNA-mediated
IOCDEKDB_04362 1.82e-28 - - - S - - - HTH-like domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)