ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEIKHJEJ_00001 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HEIKHJEJ_00002 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HEIKHJEJ_00003 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HEIKHJEJ_00004 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HEIKHJEJ_00005 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HEIKHJEJ_00006 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HEIKHJEJ_00007 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HEIKHJEJ_00008 2.46e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HEIKHJEJ_00009 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HEIKHJEJ_00010 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEIKHJEJ_00011 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HEIKHJEJ_00012 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HEIKHJEJ_00013 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HEIKHJEJ_00014 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HEIKHJEJ_00015 5.18e-81 yqhP - - - - - - -
HEIKHJEJ_00016 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEIKHJEJ_00017 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEIKHJEJ_00018 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEIKHJEJ_00019 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HEIKHJEJ_00020 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEIKHJEJ_00021 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEIKHJEJ_00022 2.72e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HEIKHJEJ_00023 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEIKHJEJ_00024 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
HEIKHJEJ_00025 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HEIKHJEJ_00026 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HEIKHJEJ_00027 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HEIKHJEJ_00028 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HEIKHJEJ_00029 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
HEIKHJEJ_00030 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
HEIKHJEJ_00031 2.84e-36 yqzE - - S - - - YqzE-like protein
HEIKHJEJ_00032 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HEIKHJEJ_00033 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HEIKHJEJ_00034 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HEIKHJEJ_00035 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HEIKHJEJ_00036 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HEIKHJEJ_00037 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HEIKHJEJ_00038 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEIKHJEJ_00039 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
HEIKHJEJ_00040 8.73e-233 yqxL - - P - - - Mg2 transporter protein
HEIKHJEJ_00041 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEIKHJEJ_00042 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEIKHJEJ_00044 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HEIKHJEJ_00045 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HEIKHJEJ_00046 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HEIKHJEJ_00047 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HEIKHJEJ_00048 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HEIKHJEJ_00049 2.69e-256 yqgU - - - - - - -
HEIKHJEJ_00050 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HEIKHJEJ_00051 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEIKHJEJ_00052 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HEIKHJEJ_00053 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HEIKHJEJ_00054 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HEIKHJEJ_00055 3.38e-14 yqgO - - - - - - -
HEIKHJEJ_00056 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEIKHJEJ_00057 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEIKHJEJ_00058 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HEIKHJEJ_00060 2.81e-67 yqzD - - - - - - -
HEIKHJEJ_00061 1.09e-93 yqzC - - S - - - YceG-like family
HEIKHJEJ_00062 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEIKHJEJ_00063 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEIKHJEJ_00064 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HEIKHJEJ_00065 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEIKHJEJ_00066 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEIKHJEJ_00067 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HEIKHJEJ_00068 1.09e-290 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HEIKHJEJ_00069 1.31e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HEIKHJEJ_00070 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HEIKHJEJ_00071 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
HEIKHJEJ_00072 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
HEIKHJEJ_00073 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEIKHJEJ_00074 2.38e-80 yqfX - - S - - - membrane
HEIKHJEJ_00075 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HEIKHJEJ_00076 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HEIKHJEJ_00077 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEIKHJEJ_00078 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HEIKHJEJ_00079 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEIKHJEJ_00080 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEIKHJEJ_00081 3.73e-46 yqfQ - - S - - - YqfQ-like protein
HEIKHJEJ_00082 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEIKHJEJ_00083 4.21e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEIKHJEJ_00084 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEIKHJEJ_00085 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HEIKHJEJ_00086 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEIKHJEJ_00087 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEIKHJEJ_00088 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HEIKHJEJ_00089 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEIKHJEJ_00090 3.29e-144 ccpN - - K - - - CBS domain
HEIKHJEJ_00091 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HEIKHJEJ_00092 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HEIKHJEJ_00093 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEIKHJEJ_00094 5.29e-27 - - - S - - - YqzL-like protein
HEIKHJEJ_00095 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEIKHJEJ_00096 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEIKHJEJ_00097 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HEIKHJEJ_00098 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEIKHJEJ_00099 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HEIKHJEJ_00101 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HEIKHJEJ_00102 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HEIKHJEJ_00103 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HEIKHJEJ_00104 2.23e-56 yqfB - - - - - - -
HEIKHJEJ_00105 4.35e-192 yqfA - - S - - - UPF0365 protein
HEIKHJEJ_00106 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HEIKHJEJ_00107 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HEIKHJEJ_00108 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEIKHJEJ_00109 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HEIKHJEJ_00110 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HEIKHJEJ_00111 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEIKHJEJ_00112 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HEIKHJEJ_00113 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEIKHJEJ_00114 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEIKHJEJ_00115 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEIKHJEJ_00116 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEIKHJEJ_00117 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HEIKHJEJ_00118 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEIKHJEJ_00119 2.28e-66 yqxA - - S - - - Protein of unknown function (DUF3679)
HEIKHJEJ_00120 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HEIKHJEJ_00121 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEIKHJEJ_00122 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEIKHJEJ_00123 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HEIKHJEJ_00124 2.36e-22 - - - S - - - YqzM-like protein
HEIKHJEJ_00125 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HEIKHJEJ_00126 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HEIKHJEJ_00127 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HEIKHJEJ_00128 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEIKHJEJ_00129 5.44e-176 yqeM - - Q - - - Methyltransferase
HEIKHJEJ_00130 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEIKHJEJ_00131 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HEIKHJEJ_00132 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEIKHJEJ_00133 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HEIKHJEJ_00134 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEIKHJEJ_00135 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEIKHJEJ_00136 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HEIKHJEJ_00138 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HEIKHJEJ_00139 1.44e-177 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_00140 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
HEIKHJEJ_00141 2.98e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HEIKHJEJ_00142 7.4e-168 - - - - - - - -
HEIKHJEJ_00143 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HEIKHJEJ_00144 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00145 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEIKHJEJ_00146 1.14e-197 yybE - - K - - - Transcriptional regulator
HEIKHJEJ_00147 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
HEIKHJEJ_00149 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
HEIKHJEJ_00150 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEIKHJEJ_00151 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HEIKHJEJ_00152 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
HEIKHJEJ_00154 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
HEIKHJEJ_00155 1.1e-20 - - - S - - - SMI1 / KNR4 family
HEIKHJEJ_00156 5.24e-60 - - - - - - - -
HEIKHJEJ_00161 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
HEIKHJEJ_00162 1.89e-40 - - - - - - - -
HEIKHJEJ_00163 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_00165 1.09e-34 - - - S - - - YCII-related domain
HEIKHJEJ_00166 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_00167 1.35e-80 yjqA - - S - - - Bacterial PH domain
HEIKHJEJ_00168 1.11e-138 yjqB - - S - - - Pfam:DUF867
HEIKHJEJ_00169 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HEIKHJEJ_00170 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
HEIKHJEJ_00171 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HEIKHJEJ_00173 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
HEIKHJEJ_00174 4.14e-150 xkdC - - L - - - Bacterial dnaA protein
HEIKHJEJ_00178 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEIKHJEJ_00179 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HEIKHJEJ_00180 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HEIKHJEJ_00181 0.0 yqbA - - S - - - portal protein
HEIKHJEJ_00182 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
HEIKHJEJ_00183 3.91e-217 xkdG - - S - - - Phage capsid family
HEIKHJEJ_00184 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
HEIKHJEJ_00185 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
HEIKHJEJ_00186 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HEIKHJEJ_00187 2.36e-100 xkdJ - - - - - - -
HEIKHJEJ_00188 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HEIKHJEJ_00189 2.45e-98 xkdM - - S - - - Phage tail tube protein
HEIKHJEJ_00190 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HEIKHJEJ_00191 0.0 xkdO - - L - - - Transglycosylase SLT domain
HEIKHJEJ_00192 1.73e-151 xkdP - - S - - - Lysin motif
HEIKHJEJ_00193 2.31e-232 xkdQ - - G - - - NLP P60 protein
HEIKHJEJ_00194 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
HEIKHJEJ_00195 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
HEIKHJEJ_00196 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEIKHJEJ_00197 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HEIKHJEJ_00198 4.43e-56 - - - - - - - -
HEIKHJEJ_00199 0.0 - - - - - - - -
HEIKHJEJ_00200 2.7e-68 xkdW - - S - - - XkdW protein
HEIKHJEJ_00201 6.35e-31 xkdX - - - - - - -
HEIKHJEJ_00202 9.79e-195 xepA - - - - - - -
HEIKHJEJ_00203 2.21e-51 xhlA - - S - - - Haemolysin XhlA
HEIKHJEJ_00204 1.15e-52 xhlB - - S - - - SPP1 phage holin
HEIKHJEJ_00205 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_00206 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HEIKHJEJ_00207 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HEIKHJEJ_00208 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HEIKHJEJ_00209 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEIKHJEJ_00210 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
HEIKHJEJ_00211 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEIKHJEJ_00212 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEIKHJEJ_00213 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEIKHJEJ_00215 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEIKHJEJ_00216 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HEIKHJEJ_00217 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HEIKHJEJ_00218 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_00219 1.23e-223 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_00220 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_00221 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEIKHJEJ_00223 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HEIKHJEJ_00224 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HEIKHJEJ_00225 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEIKHJEJ_00226 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_00227 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HEIKHJEJ_00228 9.79e-102 ykgA - - E - - - Amidinotransferase
HEIKHJEJ_00229 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
HEIKHJEJ_00230 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEIKHJEJ_00231 9.93e-15 - - - - - - - -
HEIKHJEJ_00232 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
HEIKHJEJ_00233 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
HEIKHJEJ_00234 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEIKHJEJ_00235 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HEIKHJEJ_00236 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HEIKHJEJ_00237 2.76e-216 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEIKHJEJ_00238 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEIKHJEJ_00239 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEIKHJEJ_00240 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HEIKHJEJ_00241 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
HEIKHJEJ_00242 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HEIKHJEJ_00243 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HEIKHJEJ_00244 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEIKHJEJ_00245 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEIKHJEJ_00246 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEIKHJEJ_00247 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEIKHJEJ_00248 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_00249 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HEIKHJEJ_00250 1.21e-142 ykoF - - S - - - YKOF-related Family
HEIKHJEJ_00251 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_00252 6.32e-309 ykoH - - T - - - Histidine kinase
HEIKHJEJ_00253 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
HEIKHJEJ_00254 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HEIKHJEJ_00255 1.45e-08 - - - - - - - -
HEIKHJEJ_00257 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HEIKHJEJ_00258 1.49e-70 tnrA - - K - - - transcriptional
HEIKHJEJ_00259 1.63e-25 - - - - - - - -
HEIKHJEJ_00260 3.04e-36 ykoL - - - - - - -
HEIKHJEJ_00261 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HEIKHJEJ_00262 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HEIKHJEJ_00263 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
HEIKHJEJ_00264 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HEIKHJEJ_00265 0.0 ykoS - - - - - - -
HEIKHJEJ_00266 3.86e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HEIKHJEJ_00267 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HEIKHJEJ_00268 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEIKHJEJ_00269 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HEIKHJEJ_00270 1.71e-143 ykoX - - S - - - membrane-associated protein
HEIKHJEJ_00271 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEIKHJEJ_00272 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00273 1.89e-211 rsgI - - S - - - Anti-sigma factor N-terminus
HEIKHJEJ_00274 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HEIKHJEJ_00275 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
HEIKHJEJ_00276 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HEIKHJEJ_00277 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HEIKHJEJ_00279 4.83e-30 ykzE - - - - - - -
HEIKHJEJ_00280 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEIKHJEJ_00281 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_00282 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEIKHJEJ_00284 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEIKHJEJ_00285 6.78e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEIKHJEJ_00286 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEIKHJEJ_00287 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEIKHJEJ_00288 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEIKHJEJ_00289 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEIKHJEJ_00290 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEIKHJEJ_00291 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEIKHJEJ_00292 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
HEIKHJEJ_00293 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HEIKHJEJ_00295 5.36e-203 ybaS - - S - - - Na -dependent transporter
HEIKHJEJ_00296 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
HEIKHJEJ_00297 3.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_00298 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_00299 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HEIKHJEJ_00300 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HEIKHJEJ_00301 2.33e-302 ybbC - - S - - - protein conserved in bacteria
HEIKHJEJ_00302 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HEIKHJEJ_00303 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HEIKHJEJ_00304 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_00305 2.4e-190 ybbH - - K - - - transcriptional
HEIKHJEJ_00306 1.92e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEIKHJEJ_00307 3.13e-114 ybbJ - - J - - - acetyltransferase
HEIKHJEJ_00308 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
HEIKHJEJ_00314 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_00315 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEIKHJEJ_00316 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEIKHJEJ_00317 1.6e-287 ybbR - - S - - - protein conserved in bacteria
HEIKHJEJ_00318 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEIKHJEJ_00319 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEIKHJEJ_00320 5.87e-54 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEIKHJEJ_00321 9.34e-128 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEIKHJEJ_00322 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HEIKHJEJ_00323 1.29e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEIKHJEJ_00324 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEIKHJEJ_00325 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HEIKHJEJ_00326 9.45e-121 ybcF - - P - - - carbonic anhydrase
HEIKHJEJ_00328 1.6e-63 - - - - - - - -
HEIKHJEJ_00329 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HEIKHJEJ_00330 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HEIKHJEJ_00331 2.78e-219 - - - T - - - His Kinase A (phospho-acceptor) domain
HEIKHJEJ_00333 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HEIKHJEJ_00334 1.49e-192 ybdN - - - - - - -
HEIKHJEJ_00335 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
HEIKHJEJ_00336 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_00337 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HEIKHJEJ_00338 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HEIKHJEJ_00339 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HEIKHJEJ_00340 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HEIKHJEJ_00341 1.28e-37 ybyB - - - - - - -
HEIKHJEJ_00342 0.0 ybeC - - E - - - amino acid
HEIKHJEJ_00343 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HEIKHJEJ_00344 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HEIKHJEJ_00345 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
HEIKHJEJ_00346 8.65e-202 ybfA - - K - - - FR47-like protein
HEIKHJEJ_00347 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00348 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00351 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HEIKHJEJ_00352 1.06e-207 ybfH - - EG - - - EamA-like transporter family
HEIKHJEJ_00353 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
HEIKHJEJ_00354 3.63e-43 - - - K - - - sigma factor activity
HEIKHJEJ_00355 2.73e-28 xhlB - - S - - - SPP1 phage holin
HEIKHJEJ_00356 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEIKHJEJ_00357 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEIKHJEJ_00358 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEIKHJEJ_00359 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEIKHJEJ_00360 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEIKHJEJ_00361 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HEIKHJEJ_00362 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEIKHJEJ_00363 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HEIKHJEJ_00364 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEIKHJEJ_00365 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEIKHJEJ_00366 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_00367 9.03e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_00368 6.59e-67 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_00369 9.7e-88 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_00370 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HEIKHJEJ_00371 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HEIKHJEJ_00372 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_00373 1.13e-89 - - - - - - - -
HEIKHJEJ_00374 2.66e-28 yxeD - - - - - - -
HEIKHJEJ_00375 7.32e-42 yxeE - - - - - - -
HEIKHJEJ_00378 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
HEIKHJEJ_00379 3.87e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HEIKHJEJ_00380 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEIKHJEJ_00381 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_00382 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEIKHJEJ_00383 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEIKHJEJ_00384 1.13e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_00385 2.89e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HEIKHJEJ_00386 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
HEIKHJEJ_00387 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HEIKHJEJ_00388 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
HEIKHJEJ_00389 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEIKHJEJ_00390 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEIKHJEJ_00391 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEIKHJEJ_00392 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HEIKHJEJ_00393 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEIKHJEJ_00394 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEIKHJEJ_00395 7.08e-307 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HEIKHJEJ_00396 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
HEIKHJEJ_00397 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEIKHJEJ_00398 0.0 - - - L - - - HKD family nuclease
HEIKHJEJ_00399 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
HEIKHJEJ_00400 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
HEIKHJEJ_00401 7.83e-269 - - - S - - - nuclease activity
HEIKHJEJ_00403 1.83e-221 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HEIKHJEJ_00404 3.36e-68 - - - - - - - -
HEIKHJEJ_00405 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_00406 2.15e-115 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEIKHJEJ_00407 2.02e-217 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEIKHJEJ_00408 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HEIKHJEJ_00409 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
HEIKHJEJ_00410 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_00411 5.69e-208 yxxF - - EG - - - EamA-like transporter family
HEIKHJEJ_00412 0.0 wapA - - M - - - COG3209 Rhs family protein
HEIKHJEJ_00413 3.29e-19 yxiJ - - S - - - YxiJ-like protein
HEIKHJEJ_00414 2.23e-99 wapA - - M - - - COG3209 Rhs family protein
HEIKHJEJ_00415 1.27e-69 - - - - - - - -
HEIKHJEJ_00417 6.44e-178 - - - - - - - -
HEIKHJEJ_00418 5.36e-120 - - - S - - - Protein of unknown function (DUF4240)
HEIKHJEJ_00419 7.13e-100 - - - - - - - -
HEIKHJEJ_00420 4.48e-58 - - - - - - - -
HEIKHJEJ_00421 4.67e-89 yxiG - - - - - - -
HEIKHJEJ_00422 9.7e-68 yxxG - - - - - - -
HEIKHJEJ_00423 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
HEIKHJEJ_00426 8.22e-181 - - - - - - - -
HEIKHJEJ_00427 1.01e-120 yxiI - - S - - - Protein of unknown function (DUF2716)
HEIKHJEJ_00428 1.86e-40 - - - - - - - -
HEIKHJEJ_00431 4.06e-58 yxiJ - - S - - - YxiJ-like protein
HEIKHJEJ_00434 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEIKHJEJ_00435 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEIKHJEJ_00436 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HEIKHJEJ_00437 1.07e-142 - - - - - - - -
HEIKHJEJ_00438 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEIKHJEJ_00439 7.21e-183 bglS - - M - - - licheninase activity
HEIKHJEJ_00440 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEIKHJEJ_00441 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEIKHJEJ_00442 2.28e-63 yxiS - - - - - - -
HEIKHJEJ_00443 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
HEIKHJEJ_00444 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEIKHJEJ_00445 2.42e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HEIKHJEJ_00446 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HEIKHJEJ_00447 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEIKHJEJ_00448 3.99e-149 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEIKHJEJ_00449 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEIKHJEJ_00450 3.66e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HEIKHJEJ_00451 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HEIKHJEJ_00452 2.88e-111 yxjI - - S - - - LURP-one-related
HEIKHJEJ_00455 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEIKHJEJ_00456 6.34e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HEIKHJEJ_00457 6.98e-243 - - - T - - - Signal transduction histidine kinase
HEIKHJEJ_00458 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
HEIKHJEJ_00459 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEIKHJEJ_00460 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEIKHJEJ_00461 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEIKHJEJ_00462 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HEIKHJEJ_00463 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_00464 4.77e-181 ysnF - - S - - - protein conserved in bacteria
HEIKHJEJ_00465 1.38e-84 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HEIKHJEJ_00467 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HEIKHJEJ_00468 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HEIKHJEJ_00469 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEIKHJEJ_00470 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEIKHJEJ_00471 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEIKHJEJ_00472 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEIKHJEJ_00473 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEIKHJEJ_00474 4.53e-239 ysoA - - H - - - Tetratricopeptide repeat
HEIKHJEJ_00475 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEIKHJEJ_00476 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEIKHJEJ_00477 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HEIKHJEJ_00478 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEIKHJEJ_00479 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEIKHJEJ_00480 4.77e-116 ysxD - - - - - - -
HEIKHJEJ_00481 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEIKHJEJ_00482 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HEIKHJEJ_00483 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEIKHJEJ_00484 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HEIKHJEJ_00485 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HEIKHJEJ_00486 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HEIKHJEJ_00487 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HEIKHJEJ_00488 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEIKHJEJ_00489 1.53e-35 - - - - - - - -
HEIKHJEJ_00490 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEIKHJEJ_00491 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEIKHJEJ_00492 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEIKHJEJ_00493 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HEIKHJEJ_00494 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HEIKHJEJ_00495 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HEIKHJEJ_00496 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HEIKHJEJ_00497 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEIKHJEJ_00498 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HEIKHJEJ_00499 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEIKHJEJ_00500 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HEIKHJEJ_00501 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HEIKHJEJ_00502 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HEIKHJEJ_00503 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEIKHJEJ_00504 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HEIKHJEJ_00505 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEIKHJEJ_00506 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HEIKHJEJ_00507 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEIKHJEJ_00508 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HEIKHJEJ_00509 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HEIKHJEJ_00510 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HEIKHJEJ_00511 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEIKHJEJ_00512 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HEIKHJEJ_00513 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HEIKHJEJ_00514 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEIKHJEJ_00515 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HEIKHJEJ_00516 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEIKHJEJ_00517 3.51e-164 yebC - - K - - - transcriptional regulatory protein
HEIKHJEJ_00518 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HEIKHJEJ_00519 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
HEIKHJEJ_00521 5.47e-151 yrzF - - T - - - serine threonine protein kinase
HEIKHJEJ_00522 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HEIKHJEJ_00523 0.0 csbX - - EGP - - - the major facilitator superfamily
HEIKHJEJ_00524 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HEIKHJEJ_00525 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEIKHJEJ_00526 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEIKHJEJ_00527 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HEIKHJEJ_00528 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEIKHJEJ_00529 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEIKHJEJ_00530 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HEIKHJEJ_00531 6.2e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
HEIKHJEJ_00532 8.64e-145 yrbG - - S - - - membrane
HEIKHJEJ_00533 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_00534 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
HEIKHJEJ_00535 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEIKHJEJ_00536 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HEIKHJEJ_00537 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HEIKHJEJ_00538 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEIKHJEJ_00539 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEIKHJEJ_00540 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEIKHJEJ_00541 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEIKHJEJ_00542 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HEIKHJEJ_00544 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HEIKHJEJ_00545 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEIKHJEJ_00546 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEIKHJEJ_00549 1.79e-74 - - - S - - - Bacteriophage holin family
HEIKHJEJ_00550 6.14e-142 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_00553 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HEIKHJEJ_00556 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_00557 1.64e-125 - - - K - - - Bacterial regulatory proteins, tetR family
HEIKHJEJ_00558 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HEIKHJEJ_00559 1.01e-64 yvaD - - S - - - Family of unknown function (DUF5360)
HEIKHJEJ_00560 0.0 - - - S - - - Fusaric acid resistance protein-like
HEIKHJEJ_00561 4.87e-34 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEIKHJEJ_00562 8.02e-107 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEIKHJEJ_00563 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEIKHJEJ_00564 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HEIKHJEJ_00565 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HEIKHJEJ_00566 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEIKHJEJ_00567 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HEIKHJEJ_00568 3.45e-137 bdbD - - O - - - Thioredoxin
HEIKHJEJ_00569 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HEIKHJEJ_00570 2.34e-139 yvgT - - S - - - membrane
HEIKHJEJ_00572 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEIKHJEJ_00573 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEIKHJEJ_00574 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEIKHJEJ_00575 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HEIKHJEJ_00576 9.32e-112 yvgO - - - - - - -
HEIKHJEJ_00577 7.23e-200 yvgN - - S - - - reductase
HEIKHJEJ_00578 1.74e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HEIKHJEJ_00579 6.03e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HEIKHJEJ_00580 3.46e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HEIKHJEJ_00581 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HEIKHJEJ_00582 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HEIKHJEJ_00583 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HEIKHJEJ_00584 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEIKHJEJ_00585 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_00586 3.87e-233 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_00587 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_00588 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEIKHJEJ_00589 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HEIKHJEJ_00590 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_00591 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEIKHJEJ_00592 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HEIKHJEJ_00593 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HEIKHJEJ_00594 3.46e-26 - - - S - - - YvrJ protein family
HEIKHJEJ_00595 6.67e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HEIKHJEJ_00596 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_00597 0.0 yvrG - - T - - - Histidine kinase
HEIKHJEJ_00598 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HEIKHJEJ_00599 1.01e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_00600 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HEIKHJEJ_00601 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_00602 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEIKHJEJ_00603 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HEIKHJEJ_00604 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00605 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HEIKHJEJ_00606 1.41e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEIKHJEJ_00607 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HEIKHJEJ_00608 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HEIKHJEJ_00609 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_00610 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_00611 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HEIKHJEJ_00612 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HEIKHJEJ_00613 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEIKHJEJ_00614 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
HEIKHJEJ_00615 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEIKHJEJ_00618 4.44e-38 bhlA - - S - - - BhlA holin family
HEIKHJEJ_00619 3.19e-41 xhlB - - S - - - SPP1 phage holin
HEIKHJEJ_00620 4.08e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_00621 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HEIKHJEJ_00622 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEIKHJEJ_00623 6.2e-28 - - - S - - - Domain of unknown function (DUF4917)
HEIKHJEJ_00624 3.12e-09 - - - - - - - -
HEIKHJEJ_00625 1.68e-13 - - - - - - - -
HEIKHJEJ_00627 1.46e-105 - - - - - - - -
HEIKHJEJ_00628 4.13e-51 - - - - - - - -
HEIKHJEJ_00629 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
HEIKHJEJ_00630 9.3e-51 ynaC - - - - - - -
HEIKHJEJ_00631 3.65e-81 ynaC - - - - - - -
HEIKHJEJ_00638 5.89e-58 - - - L - - - Phage integrase family
HEIKHJEJ_00639 5.52e-31 - - - M - - - ArpU family transcriptional regulator
HEIKHJEJ_00644 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEIKHJEJ_00645 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEIKHJEJ_00646 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HEIKHJEJ_00647 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HEIKHJEJ_00648 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEIKHJEJ_00649 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEIKHJEJ_00650 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEIKHJEJ_00651 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HEIKHJEJ_00652 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HEIKHJEJ_00653 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEIKHJEJ_00654 1.82e-276 pbpX - - V - - - Beta-lactamase
HEIKHJEJ_00655 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEIKHJEJ_00656 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEIKHJEJ_00657 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEIKHJEJ_00658 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HEIKHJEJ_00659 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HEIKHJEJ_00660 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HEIKHJEJ_00661 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEIKHJEJ_00662 2.37e-309 ymfH - - S - - - zinc protease
HEIKHJEJ_00663 9.47e-299 albE - - S - - - Peptidase M16
HEIKHJEJ_00664 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00665 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_00666 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEIKHJEJ_00667 4.94e-44 - - - S - - - YlzJ-like protein
HEIKHJEJ_00668 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HEIKHJEJ_00669 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEIKHJEJ_00670 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEIKHJEJ_00671 2.83e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEIKHJEJ_00672 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEIKHJEJ_00673 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEIKHJEJ_00674 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HEIKHJEJ_00675 1.53e-56 ymxH - - S - - - YlmC YmxH family
HEIKHJEJ_00676 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HEIKHJEJ_00677 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HEIKHJEJ_00678 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEIKHJEJ_00679 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEIKHJEJ_00680 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEIKHJEJ_00681 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEIKHJEJ_00682 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEIKHJEJ_00683 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HEIKHJEJ_00684 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEIKHJEJ_00685 6.16e-63 ylxQ - - J - - - ribosomal protein
HEIKHJEJ_00686 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HEIKHJEJ_00687 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEIKHJEJ_00688 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEIKHJEJ_00689 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEIKHJEJ_00690 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEIKHJEJ_00691 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HEIKHJEJ_00692 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEIKHJEJ_00693 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HEIKHJEJ_00694 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEIKHJEJ_00695 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEIKHJEJ_00696 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEIKHJEJ_00697 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEIKHJEJ_00698 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEIKHJEJ_00699 2.81e-100 ylxL - - - - - - -
HEIKHJEJ_00700 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00701 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEIKHJEJ_00702 4.54e-60 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEIKHJEJ_00703 5.88e-54 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEIKHJEJ_00704 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HEIKHJEJ_00705 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HEIKHJEJ_00706 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEIKHJEJ_00707 1.28e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HEIKHJEJ_00708 1.89e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HEIKHJEJ_00709 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEIKHJEJ_00710 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEIKHJEJ_00711 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HEIKHJEJ_00712 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HEIKHJEJ_00713 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HEIKHJEJ_00714 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HEIKHJEJ_00715 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HEIKHJEJ_00716 3.24e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEIKHJEJ_00717 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEIKHJEJ_00718 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HEIKHJEJ_00719 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HEIKHJEJ_00720 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HEIKHJEJ_00721 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HEIKHJEJ_00722 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
HEIKHJEJ_00723 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HEIKHJEJ_00724 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEIKHJEJ_00725 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HEIKHJEJ_00726 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEIKHJEJ_00727 7.5e-188 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HEIKHJEJ_00728 1.07e-95 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HEIKHJEJ_00729 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HEIKHJEJ_00730 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HEIKHJEJ_00731 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEIKHJEJ_00732 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEIKHJEJ_00733 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEIKHJEJ_00734 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEIKHJEJ_00735 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HEIKHJEJ_00736 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEIKHJEJ_00737 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEIKHJEJ_00738 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HEIKHJEJ_00739 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEIKHJEJ_00740 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEIKHJEJ_00741 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HEIKHJEJ_00742 0.0 ylqG - - - - - - -
HEIKHJEJ_00743 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEIKHJEJ_00744 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEIKHJEJ_00745 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEIKHJEJ_00746 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEIKHJEJ_00747 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEIKHJEJ_00748 3.41e-80 ylqD - - S - - - YlqD protein
HEIKHJEJ_00749 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEIKHJEJ_00750 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEIKHJEJ_00751 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEIKHJEJ_00752 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEIKHJEJ_00753 1.67e-114 - - - - - - - -
HEIKHJEJ_00754 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEIKHJEJ_00755 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEIKHJEJ_00756 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEIKHJEJ_00757 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEIKHJEJ_00758 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEIKHJEJ_00759 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HEIKHJEJ_00760 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEIKHJEJ_00761 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEIKHJEJ_00762 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEIKHJEJ_00763 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HEIKHJEJ_00764 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HEIKHJEJ_00765 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HEIKHJEJ_00766 3.65e-78 yloU - - S - - - protein conserved in bacteria
HEIKHJEJ_00767 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEIKHJEJ_00768 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEIKHJEJ_00769 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEIKHJEJ_00770 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEIKHJEJ_00771 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEIKHJEJ_00772 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HEIKHJEJ_00773 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEIKHJEJ_00774 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEIKHJEJ_00775 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEIKHJEJ_00776 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEIKHJEJ_00777 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEIKHJEJ_00778 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEIKHJEJ_00779 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEIKHJEJ_00780 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEIKHJEJ_00781 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HEIKHJEJ_00782 8.41e-202 yloC - - S - - - stress-induced protein
HEIKHJEJ_00783 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HEIKHJEJ_00784 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HEIKHJEJ_00785 3.78e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HEIKHJEJ_00786 8.38e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HEIKHJEJ_00787 1.45e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HEIKHJEJ_00788 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HEIKHJEJ_00789 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HEIKHJEJ_00790 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HEIKHJEJ_00791 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HEIKHJEJ_00792 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEIKHJEJ_00793 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEIKHJEJ_00794 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEIKHJEJ_00795 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEIKHJEJ_00796 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HEIKHJEJ_00797 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEIKHJEJ_00798 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEIKHJEJ_00799 5.99e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEIKHJEJ_00800 8.02e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HEIKHJEJ_00801 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEIKHJEJ_00802 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEIKHJEJ_00803 1.89e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEIKHJEJ_00804 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HEIKHJEJ_00805 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEIKHJEJ_00806 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HEIKHJEJ_00807 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
HEIKHJEJ_00808 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HEIKHJEJ_00809 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEIKHJEJ_00810 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEIKHJEJ_00811 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HEIKHJEJ_00812 3.58e-51 ylmC - - S - - - sporulation protein
HEIKHJEJ_00813 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HEIKHJEJ_00814 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEIKHJEJ_00815 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00816 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00817 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEIKHJEJ_00819 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HEIKHJEJ_00820 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEIKHJEJ_00821 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEIKHJEJ_00822 5.37e-76 sbp - - S - - - small basic protein
HEIKHJEJ_00823 8.67e-132 ylxX - - S - - - protein conserved in bacteria
HEIKHJEJ_00824 3.45e-146 ylxW - - S - - - protein conserved in bacteria
HEIKHJEJ_00825 1.37e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEIKHJEJ_00826 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HEIKHJEJ_00827 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEIKHJEJ_00828 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEIKHJEJ_00829 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEIKHJEJ_00830 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEIKHJEJ_00831 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEIKHJEJ_00832 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HEIKHJEJ_00833 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEIKHJEJ_00834 3.42e-68 ftsL - - D - - - Essential cell division protein
HEIKHJEJ_00835 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEIKHJEJ_00836 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEIKHJEJ_00837 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEIKHJEJ_00838 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEIKHJEJ_00839 1.33e-115 ylbP - - K - - - n-acetyltransferase
HEIKHJEJ_00840 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEIKHJEJ_00841 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HEIKHJEJ_00842 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HEIKHJEJ_00844 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
HEIKHJEJ_00845 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HEIKHJEJ_00846 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HEIKHJEJ_00847 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HEIKHJEJ_00848 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEIKHJEJ_00849 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HEIKHJEJ_00850 4.36e-52 ylbG - - S - - - UPF0298 protein
HEIKHJEJ_00851 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HEIKHJEJ_00852 1.73e-48 ylbE - - S - - - YlbE-like protein
HEIKHJEJ_00853 3.24e-89 ylbD - - S - - - Putative coat protein
HEIKHJEJ_00854 2.18e-256 ylbC - - S - - - protein with SCP PR1 domains
HEIKHJEJ_00855 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HEIKHJEJ_00856 1.88e-80 ylbA - - S - - - YugN-like family
HEIKHJEJ_00857 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HEIKHJEJ_00858 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEIKHJEJ_00859 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEIKHJEJ_00860 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEIKHJEJ_00861 2.28e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEIKHJEJ_00862 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEIKHJEJ_00863 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEIKHJEJ_00864 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEIKHJEJ_00865 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEIKHJEJ_00866 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HEIKHJEJ_00867 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HEIKHJEJ_00868 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEIKHJEJ_00869 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HEIKHJEJ_00870 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEIKHJEJ_00871 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HEIKHJEJ_00872 4.4e-63 ylaH - - S - - - YlaH-like protein
HEIKHJEJ_00873 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEIKHJEJ_00874 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HEIKHJEJ_00875 1.74e-57 ylaE - - - - - - -
HEIKHJEJ_00877 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_00878 1.44e-56 ylaB - - - - - - -
HEIKHJEJ_00879 0.0 ylaA - - - - - - -
HEIKHJEJ_00880 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HEIKHJEJ_00881 2.57e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEIKHJEJ_00883 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEIKHJEJ_00884 0.0 rocB - - E - - - arginine degradation protein
HEIKHJEJ_00885 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEIKHJEJ_00886 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEIKHJEJ_00887 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_00888 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HEIKHJEJ_00889 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HEIKHJEJ_00890 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_00892 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
HEIKHJEJ_00894 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEIKHJEJ_00895 1.87e-65 yqiX - - S - - - YolD-like protein
HEIKHJEJ_00896 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HEIKHJEJ_00897 2.63e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HEIKHJEJ_00898 6.8e-250 yqkA - - K - - - GrpB protein
HEIKHJEJ_00899 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HEIKHJEJ_00900 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HEIKHJEJ_00901 1.88e-221 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HEIKHJEJ_00902 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
HEIKHJEJ_00903 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HEIKHJEJ_00904 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HEIKHJEJ_00905 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HEIKHJEJ_00906 1.45e-280 yqxK - - L - - - DNA helicase
HEIKHJEJ_00907 3.18e-77 ansR - - K - - - Transcriptional regulator
HEIKHJEJ_00908 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HEIKHJEJ_00909 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HEIKHJEJ_00910 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HEIKHJEJ_00911 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HEIKHJEJ_00912 1.47e-41 yqkK - - - - - - -
HEIKHJEJ_00913 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEIKHJEJ_00914 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEIKHJEJ_00915 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
HEIKHJEJ_00916 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HEIKHJEJ_00917 2.28e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEIKHJEJ_00918 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEIKHJEJ_00919 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEIKHJEJ_00920 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HEIKHJEJ_00921 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEIKHJEJ_00922 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_00923 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HEIKHJEJ_00924 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HEIKHJEJ_00925 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HEIKHJEJ_00926 1.21e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HEIKHJEJ_00927 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HEIKHJEJ_00928 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HEIKHJEJ_00929 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HEIKHJEJ_00930 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEIKHJEJ_00931 3.12e-192 ypuA - - S - - - Secreted protein
HEIKHJEJ_00932 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEIKHJEJ_00933 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEIKHJEJ_00938 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_00940 1.82e-55 - - - - - - - -
HEIKHJEJ_00941 7.74e-301 - - - I - - - Pfam Lipase (class 3)
HEIKHJEJ_00942 1.62e-37 - - - S - - - Protein of unknown function (DUF1433)
HEIKHJEJ_00943 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HEIKHJEJ_00944 1.94e-270 yfjB - - - - - - -
HEIKHJEJ_00945 1.02e-184 yfjC - - - - - - -
HEIKHJEJ_00946 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HEIKHJEJ_00947 1e-105 - - - S - - - Family of unknown function (DUF5381)
HEIKHJEJ_00948 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HEIKHJEJ_00949 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HEIKHJEJ_00950 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HEIKHJEJ_00951 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEIKHJEJ_00952 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEIKHJEJ_00953 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEIKHJEJ_00954 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEIKHJEJ_00956 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
HEIKHJEJ_00957 7.83e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEIKHJEJ_00958 3.04e-59 - - - S - - - YfzA-like protein
HEIKHJEJ_00959 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEIKHJEJ_00960 5.57e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEIKHJEJ_00961 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HEIKHJEJ_00962 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEIKHJEJ_00963 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HEIKHJEJ_00964 3.26e-36 yfjT - - - - - - -
HEIKHJEJ_00965 1.76e-283 yfkA - - S - - - YfkB-like domain
HEIKHJEJ_00966 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HEIKHJEJ_00967 3.69e-189 yfkD - - S - - - YfkD-like protein
HEIKHJEJ_00968 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HEIKHJEJ_00969 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00970 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HEIKHJEJ_00971 1.03e-66 yfkI - - S - - - gas vesicle protein
HEIKHJEJ_00972 5.04e-109 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEIKHJEJ_00973 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
HEIKHJEJ_00974 5.94e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_00978 5.48e-110 - - - - - - - -
HEIKHJEJ_00979 5.32e-26 - - - - - - - -
HEIKHJEJ_00986 0.0 - - - D - - - Phage tail tape measure protein
HEIKHJEJ_00988 2.31e-114 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_00989 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HEIKHJEJ_00990 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEIKHJEJ_00992 6.7e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HEIKHJEJ_00993 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEIKHJEJ_00994 1.97e-46 yuiB - - S - - - Putative membrane protein
HEIKHJEJ_00995 2.69e-150 yuiC - - S - - - protein conserved in bacteria
HEIKHJEJ_00996 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HEIKHJEJ_00997 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEIKHJEJ_00998 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HEIKHJEJ_00999 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HEIKHJEJ_01000 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HEIKHJEJ_01001 2.18e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
HEIKHJEJ_01002 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_01003 1.22e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HEIKHJEJ_01004 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HEIKHJEJ_01005 1.82e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HEIKHJEJ_01006 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_01007 8.23e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HEIKHJEJ_01008 2.42e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HEIKHJEJ_01009 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HEIKHJEJ_01010 1.71e-291 yukF - - QT - - - Transcriptional regulator
HEIKHJEJ_01011 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HEIKHJEJ_01012 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HEIKHJEJ_01013 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HEIKHJEJ_01014 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEIKHJEJ_01015 0.0 yueB - - S - - - type VII secretion protein EsaA
HEIKHJEJ_01016 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
HEIKHJEJ_01017 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_01018 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HEIKHJEJ_01019 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
HEIKHJEJ_01020 1.35e-244 yueF - - S - - - transporter activity
HEIKHJEJ_01021 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HEIKHJEJ_01022 1.63e-52 yueH - - S - - - YueH-like protein
HEIKHJEJ_01023 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
HEIKHJEJ_01024 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HEIKHJEJ_01025 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEIKHJEJ_01026 1.97e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HEIKHJEJ_01027 8.73e-09 yuzC - - - - - - -
HEIKHJEJ_01028 6.29e-10 - - - S - - - DegQ (SacQ) family
HEIKHJEJ_01029 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
HEIKHJEJ_01031 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_01032 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_01033 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HEIKHJEJ_01034 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HEIKHJEJ_01035 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEIKHJEJ_01036 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEIKHJEJ_01037 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEIKHJEJ_01038 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEIKHJEJ_01039 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEIKHJEJ_01040 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEIKHJEJ_01041 1.42e-21 - - - - - - - -
HEIKHJEJ_01042 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HEIKHJEJ_01043 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEIKHJEJ_01044 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEIKHJEJ_01045 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_01046 2.24e-251 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HEIKHJEJ_01047 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HEIKHJEJ_01048 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEIKHJEJ_01049 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HEIKHJEJ_01050 1.92e-97 yuxK - - S - - - protein conserved in bacteria
HEIKHJEJ_01051 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HEIKHJEJ_01052 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
HEIKHJEJ_01054 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HEIKHJEJ_01055 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HEIKHJEJ_01056 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_01057 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEIKHJEJ_01058 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HEIKHJEJ_01059 9.89e-201 yugF - - I - - - Hydrolase
HEIKHJEJ_01060 6.74e-112 alaR - - K - - - Transcriptional regulator
HEIKHJEJ_01061 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HEIKHJEJ_01062 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HEIKHJEJ_01063 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HEIKHJEJ_01064 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEIKHJEJ_01065 1.26e-287 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HEIKHJEJ_01066 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEIKHJEJ_01068 4.22e-95 yugN - - S - - - YugN-like family
HEIKHJEJ_01069 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HEIKHJEJ_01070 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
HEIKHJEJ_01071 2.16e-48 - - - - - - - -
HEIKHJEJ_01072 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HEIKHJEJ_01073 4.18e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEIKHJEJ_01074 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEIKHJEJ_01075 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
HEIKHJEJ_01076 2.04e-47 - - - - - - - -
HEIKHJEJ_01077 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HEIKHJEJ_01078 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01079 4.17e-63 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01080 2.23e-199 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01081 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01082 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01083 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_01084 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HEIKHJEJ_01085 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEIKHJEJ_01086 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HEIKHJEJ_01087 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HEIKHJEJ_01088 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HEIKHJEJ_01089 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEIKHJEJ_01090 1.73e-252 yubA - - S - - - transporter activity
HEIKHJEJ_01091 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEIKHJEJ_01093 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HEIKHJEJ_01094 0.0 yubD - - P - - - Major Facilitator Superfamily
HEIKHJEJ_01095 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEIKHJEJ_01096 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HEIKHJEJ_01097 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HEIKHJEJ_01098 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HEIKHJEJ_01099 5.83e-118 yuaB - - - - - - -
HEIKHJEJ_01100 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HEIKHJEJ_01101 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEIKHJEJ_01102 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HEIKHJEJ_01103 3.92e-135 yuaD - - - - - - -
HEIKHJEJ_01104 6.53e-108 yuaE - - S - - - DinB superfamily
HEIKHJEJ_01105 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HEIKHJEJ_01106 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HEIKHJEJ_01107 5.71e-121 - - - M - - - FR47-like protein
HEIKHJEJ_01108 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HEIKHJEJ_01109 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
HEIKHJEJ_01110 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
HEIKHJEJ_01111 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
HEIKHJEJ_01112 2.74e-60 cgeA - - - ko:K06319 - ko00000 -
HEIKHJEJ_01113 9.37e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
HEIKHJEJ_01114 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
HEIKHJEJ_01115 2.73e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HEIKHJEJ_01116 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HEIKHJEJ_01117 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEIKHJEJ_01118 4.14e-94 ypoP - - K - - - transcriptional
HEIKHJEJ_01119 7.03e-290 mepA - - V - - - MATE efflux family protein
HEIKHJEJ_01120 8.69e-40 ypmT - - S - - - Uncharacterized ympT
HEIKHJEJ_01121 5.59e-128 ypmS - - S - - - protein conserved in bacteria
HEIKHJEJ_01122 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HEIKHJEJ_01123 6.15e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEIKHJEJ_01124 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
HEIKHJEJ_01125 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEIKHJEJ_01126 1.29e-232 yplP - - K - - - Transcriptional regulator
HEIKHJEJ_01127 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HEIKHJEJ_01128 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEIKHJEJ_01129 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEIKHJEJ_01130 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HEIKHJEJ_01131 2.01e-147 ypjP - - S - - - YpjP-like protein
HEIKHJEJ_01132 8.04e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HEIKHJEJ_01133 2.78e-98 yphP - - S - - - Belongs to the UPF0403 family
HEIKHJEJ_01134 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HEIKHJEJ_01135 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HEIKHJEJ_01136 2.42e-140 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HEIKHJEJ_01137 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HEIKHJEJ_01138 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEIKHJEJ_01139 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEIKHJEJ_01140 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HEIKHJEJ_01141 1.17e-22 degR - - - - - - -
HEIKHJEJ_01142 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HEIKHJEJ_01143 7.99e-41 ypeQ - - S - - - Zinc-finger
HEIKHJEJ_01144 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HEIKHJEJ_01145 4.27e-155 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEIKHJEJ_01146 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HEIKHJEJ_01147 2.59e-05 - - - - ko:K06429 - ko00000 -
HEIKHJEJ_01148 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HEIKHJEJ_01149 1.08e-11 - - - - - - - -
HEIKHJEJ_01150 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HEIKHJEJ_01151 0.0 ypbR - - S - - - Dynamin family
HEIKHJEJ_01152 9.54e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HEIKHJEJ_01153 3.58e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HEIKHJEJ_01154 1.43e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HEIKHJEJ_01155 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEIKHJEJ_01156 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEIKHJEJ_01157 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HEIKHJEJ_01158 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HEIKHJEJ_01159 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HEIKHJEJ_01160 1.57e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HEIKHJEJ_01161 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEIKHJEJ_01162 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_01163 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HEIKHJEJ_01165 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEIKHJEJ_01166 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEIKHJEJ_01167 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
HEIKHJEJ_01168 1.98e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HEIKHJEJ_01169 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEIKHJEJ_01170 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HEIKHJEJ_01171 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEIKHJEJ_01172 8.72e-68 yppG - - S - - - YppG-like protein
HEIKHJEJ_01173 9.21e-11 - - - S - - - YppF-like protein
HEIKHJEJ_01174 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HEIKHJEJ_01177 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
HEIKHJEJ_01178 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEIKHJEJ_01179 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEIKHJEJ_01180 1.43e-121 ypoC - - - - - - -
HEIKHJEJ_01181 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEIKHJEJ_01182 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HEIKHJEJ_01183 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HEIKHJEJ_01184 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEIKHJEJ_01185 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HEIKHJEJ_01186 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HEIKHJEJ_01187 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HEIKHJEJ_01188 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEIKHJEJ_01189 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEIKHJEJ_01190 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEIKHJEJ_01191 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEIKHJEJ_01192 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEIKHJEJ_01193 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEIKHJEJ_01194 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HEIKHJEJ_01195 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HEIKHJEJ_01196 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEIKHJEJ_01197 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HEIKHJEJ_01198 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEIKHJEJ_01199 6.56e-181 ypjB - - S - - - sporulation protein
HEIKHJEJ_01200 1.15e-125 ypjA - - S - - - membrane
HEIKHJEJ_01201 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HEIKHJEJ_01202 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HEIKHJEJ_01203 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HEIKHJEJ_01204 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HEIKHJEJ_01205 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
HEIKHJEJ_01206 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
HEIKHJEJ_01207 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEIKHJEJ_01208 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HEIKHJEJ_01209 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEIKHJEJ_01210 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEIKHJEJ_01211 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEIKHJEJ_01212 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HEIKHJEJ_01213 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HEIKHJEJ_01214 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEIKHJEJ_01215 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEIKHJEJ_01216 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEIKHJEJ_01217 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEIKHJEJ_01218 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEIKHJEJ_01219 1.5e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HEIKHJEJ_01220 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEIKHJEJ_01221 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEIKHJEJ_01222 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEIKHJEJ_01223 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEIKHJEJ_01224 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEIKHJEJ_01225 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HEIKHJEJ_01226 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEIKHJEJ_01227 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEIKHJEJ_01228 8.71e-176 yphF - - - - - - -
HEIKHJEJ_01229 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
HEIKHJEJ_01230 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEIKHJEJ_01231 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEIKHJEJ_01232 2.06e-38 ypzH - - - - - - -
HEIKHJEJ_01233 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HEIKHJEJ_01234 1.11e-133 yphA - - - - - - -
HEIKHJEJ_01235 1.13e-11 - - - S - - - YpzI-like protein
HEIKHJEJ_01236 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEIKHJEJ_01237 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HEIKHJEJ_01238 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEIKHJEJ_01239 4.83e-30 - - - S - - - Family of unknown function (DUF5359)
HEIKHJEJ_01240 2.57e-141 ypfA - - M - - - Flagellar protein YcgR
HEIKHJEJ_01241 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HEIKHJEJ_01242 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HEIKHJEJ_01243 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HEIKHJEJ_01244 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HEIKHJEJ_01245 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEIKHJEJ_01246 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEIKHJEJ_01247 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HEIKHJEJ_01248 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HEIKHJEJ_01249 5.04e-148 ypbE - - M - - - Lysin motif
HEIKHJEJ_01250 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HEIKHJEJ_01251 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEIKHJEJ_01252 1.28e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HEIKHJEJ_01253 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HEIKHJEJ_01254 1.78e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEIKHJEJ_01255 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEIKHJEJ_01256 2.28e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEIKHJEJ_01257 8.13e-245 rsiX - - - - - - -
HEIKHJEJ_01258 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_01259 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_01260 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_01261 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEIKHJEJ_01262 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HEIKHJEJ_01263 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEIKHJEJ_01264 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEIKHJEJ_01265 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HEIKHJEJ_01266 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HEIKHJEJ_01267 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEIKHJEJ_01268 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
HEIKHJEJ_01270 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEIKHJEJ_01272 9.49e-89 - - - - - - - -
HEIKHJEJ_01273 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEIKHJEJ_01275 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HEIKHJEJ_01276 4.42e-254 yycP - - - - - - -
HEIKHJEJ_01277 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEIKHJEJ_01278 3.04e-110 yycN - - K - - - Acetyltransferase
HEIKHJEJ_01279 8.7e-239 - - - S - - - aspartate phosphatase
HEIKHJEJ_01281 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HEIKHJEJ_01282 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEIKHJEJ_01283 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEIKHJEJ_01284 5.82e-20 - - - - - - - -
HEIKHJEJ_01285 4.85e-119 - - - - - - - -
HEIKHJEJ_01286 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
HEIKHJEJ_01287 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEIKHJEJ_01288 2.31e-54 sdpR - - K - - - transcriptional
HEIKHJEJ_01289 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEIKHJEJ_01290 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEIKHJEJ_01291 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEIKHJEJ_01292 3.44e-200 yycI - - S - - - protein conserved in bacteria
HEIKHJEJ_01293 0.0 yycH - - S - - - protein conserved in bacteria
HEIKHJEJ_01294 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_01295 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_01300 1.75e-312 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEIKHJEJ_01301 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_01302 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEIKHJEJ_01303 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HEIKHJEJ_01305 1.89e-22 yycC - - K - - - YycC-like protein
HEIKHJEJ_01306 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HEIKHJEJ_01307 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEIKHJEJ_01308 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HEIKHJEJ_01309 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HEIKHJEJ_01310 1.5e-204 yybS - - S - - - membrane
HEIKHJEJ_01312 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
HEIKHJEJ_01313 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
HEIKHJEJ_01314 1.3e-87 yybR - - K - - - Transcriptional regulator
HEIKHJEJ_01315 1.4e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HEIKHJEJ_01316 1.11e-90 - - - - - - - -
HEIKHJEJ_01318 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_01319 9.88e-141 - - - K - - - TipAS antibiotic-recognition domain
HEIKHJEJ_01320 2.05e-183 - - - - - - - -
HEIKHJEJ_01321 2.39e-85 - - - S - - - SnoaL-like domain
HEIKHJEJ_01322 2.81e-162 yybG - - S - - - Pentapeptide repeat-containing protein
HEIKHJEJ_01323 6.02e-127 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_01324 2.04e-88 - - - S - - - Metallo-beta-lactamase superfamily
HEIKHJEJ_01325 4.54e-100 yybA - - K - - - transcriptional
HEIKHJEJ_01326 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_01327 1.01e-123 yyaS - - S ko:K07149 - ko00000 Membrane
HEIKHJEJ_01328 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HEIKHJEJ_01329 1.5e-85 - - - S - - - YjbR
HEIKHJEJ_01330 8.28e-135 yyaP - - H - - - RibD C-terminal domain
HEIKHJEJ_01331 2.59e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HEIKHJEJ_01332 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
HEIKHJEJ_01333 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HEIKHJEJ_01334 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEIKHJEJ_01335 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HEIKHJEJ_01336 3.43e-81 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_01337 8.75e-26 - - - H - - - ThiF family
HEIKHJEJ_01338 1.15e-30 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
HEIKHJEJ_01339 3.58e-50 - - - EGP - - - PFAM Major Facilitator Superfamily
HEIKHJEJ_01340 5.01e-78 ccpB - - K - - - Transcriptional regulator
HEIKHJEJ_01341 1.15e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEIKHJEJ_01342 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEIKHJEJ_01343 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEIKHJEJ_01344 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEIKHJEJ_01345 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEIKHJEJ_01346 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEIKHJEJ_01347 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HEIKHJEJ_01348 5.34e-227 yyaD - - S - - - Membrane
HEIKHJEJ_01349 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HEIKHJEJ_01350 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEIKHJEJ_01351 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HEIKHJEJ_01352 3.77e-97 - - - S - - - Bacterial PH domain
HEIKHJEJ_01353 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEIKHJEJ_01354 2.9e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEIKHJEJ_01355 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEIKHJEJ_01356 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEIKHJEJ_01357 2.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HEIKHJEJ_01358 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEIKHJEJ_01359 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEIKHJEJ_01360 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEIKHJEJ_01361 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEIKHJEJ_01362 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HEIKHJEJ_01363 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEIKHJEJ_01364 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HEIKHJEJ_01365 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEIKHJEJ_01366 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEIKHJEJ_01367 6.44e-139 yodC - - C - - - nitroreductase
HEIKHJEJ_01368 2.63e-73 yodB - - K - - - transcriptional
HEIKHJEJ_01369 2.3e-83 iolK - - S - - - tautomerase
HEIKHJEJ_01370 7.01e-96 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HEIKHJEJ_01371 1.26e-168 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HEIKHJEJ_01372 5.59e-14 - - - - - - - -
HEIKHJEJ_01373 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HEIKHJEJ_01374 1.64e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HEIKHJEJ_01375 1.85e-58 - - - - - - - -
HEIKHJEJ_01376 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HEIKHJEJ_01377 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HEIKHJEJ_01378 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEIKHJEJ_01379 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HEIKHJEJ_01381 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEIKHJEJ_01382 3.79e-292 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HEIKHJEJ_01383 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEIKHJEJ_01384 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEIKHJEJ_01385 8.98e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HEIKHJEJ_01386 0.0 yojO - - P - - - Von Willebrand factor
HEIKHJEJ_01387 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEIKHJEJ_01388 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEIKHJEJ_01389 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
HEIKHJEJ_01390 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEIKHJEJ_01391 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HEIKHJEJ_01392 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HEIKHJEJ_01393 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEIKHJEJ_01394 1.91e-42 yozC - - - - - - -
HEIKHJEJ_01395 2.17e-74 yozO - - S - - - Bacterial PH domain
HEIKHJEJ_01396 1.83e-49 yocN - - - - - - -
HEIKHJEJ_01397 2.94e-55 yozN - - - - - - -
HEIKHJEJ_01398 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEIKHJEJ_01399 3.93e-41 - - - - - - - -
HEIKHJEJ_01400 4.29e-70 yocL - - - - - - -
HEIKHJEJ_01401 2.87e-107 yocK - - T - - - general stress protein
HEIKHJEJ_01402 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEIKHJEJ_01403 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEIKHJEJ_01404 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
HEIKHJEJ_01406 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_01407 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_01408 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HEIKHJEJ_01409 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HEIKHJEJ_01410 1.08e-121 yocC - - - - - - -
HEIKHJEJ_01411 8.68e-67 - - - - - - - -
HEIKHJEJ_01412 9.86e-88 - - - - - - - -
HEIKHJEJ_01413 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HEIKHJEJ_01414 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEIKHJEJ_01415 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HEIKHJEJ_01416 2.58e-121 yobW - - - - - - -
HEIKHJEJ_01417 2.76e-220 yobV - - K - - - WYL domain
HEIKHJEJ_01418 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
HEIKHJEJ_01419 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEIKHJEJ_01420 7.27e-126 yobS - - K - - - Transcriptional regulator
HEIKHJEJ_01421 1.98e-178 - - - J - - - FR47-like protein
HEIKHJEJ_01422 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HEIKHJEJ_01423 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HEIKHJEJ_01424 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HEIKHJEJ_01425 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
HEIKHJEJ_01426 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEIKHJEJ_01427 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
HEIKHJEJ_01428 5.49e-102 - - - S - - - SMI1-KNR4 cell-wall
HEIKHJEJ_01429 5.44e-124 yokK - - S - - - SMI1 / KNR4 family
HEIKHJEJ_01430 2.06e-125 - - - J - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_01433 2.34e-14 - - - S - - - YolD-like protein
HEIKHJEJ_01434 4.84e-85 - - - S - - - damaged DNA binding
HEIKHJEJ_01435 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEIKHJEJ_01436 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEIKHJEJ_01437 8.93e-124 - - - S - - - YcxB-like protein
HEIKHJEJ_01438 3.27e-205 ycxC - - EG - - - EamA-like transporter family
HEIKHJEJ_01439 2.81e-316 ycxD - - K - - - GntR family transcriptional regulator
HEIKHJEJ_01440 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HEIKHJEJ_01441 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
HEIKHJEJ_01442 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEIKHJEJ_01443 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEIKHJEJ_01444 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEIKHJEJ_01445 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HEIKHJEJ_01446 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEIKHJEJ_01447 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEIKHJEJ_01448 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HEIKHJEJ_01449 6.45e-55 yclD - - - - - - -
HEIKHJEJ_01450 1.84e-200 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HEIKHJEJ_01451 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HEIKHJEJ_01452 0.0 yclG - - M - - - Pectate lyase superfamily protein
HEIKHJEJ_01454 8.36e-119 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HEIKHJEJ_01455 3.13e-210 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HEIKHJEJ_01456 8.22e-288 gerKC - - S ko:K06297 - ko00000 spore germination
HEIKHJEJ_01457 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HEIKHJEJ_01458 1.38e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEIKHJEJ_01459 5.33e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HEIKHJEJ_01460 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_01461 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEIKHJEJ_01462 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEIKHJEJ_01464 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEIKHJEJ_01465 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEIKHJEJ_01467 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_01468 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_01469 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_01470 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HEIKHJEJ_01471 1.18e-96 - - - V - - - Restriction endonuclease
HEIKHJEJ_01472 0.0 ycnB - - EGP - - - the major facilitator superfamily
HEIKHJEJ_01473 5.87e-198 ycnC - - K - - - Transcriptional regulator
HEIKHJEJ_01474 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HEIKHJEJ_01475 1.68e-60 ycnE - - S - - - Monooxygenase
HEIKHJEJ_01476 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEIKHJEJ_01477 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_01478 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEIKHJEJ_01479 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEIKHJEJ_01480 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HEIKHJEJ_01481 1.39e-185 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_01482 1.34e-132 ycnI - - S - - - protein conserved in bacteria
HEIKHJEJ_01483 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HEIKHJEJ_01484 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEIKHJEJ_01485 1.34e-74 - - - - - - - -
HEIKHJEJ_01486 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEIKHJEJ_01487 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEIKHJEJ_01488 3.1e-268 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEIKHJEJ_01489 3.39e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HEIKHJEJ_01491 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEIKHJEJ_01492 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HEIKHJEJ_01493 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HEIKHJEJ_01495 3.15e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEIKHJEJ_01496 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HEIKHJEJ_01497 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEIKHJEJ_01498 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HEIKHJEJ_01499 2.8e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HEIKHJEJ_01500 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HEIKHJEJ_01501 1.55e-170 kipR - - K - - - Transcriptional regulator
HEIKHJEJ_01502 1.2e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HEIKHJEJ_01504 8.97e-65 yczJ - - S - - - biosynthesis
HEIKHJEJ_01505 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HEIKHJEJ_01506 3.5e-219 ycsN - - S - - - Oxidoreductase
HEIKHJEJ_01507 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HEIKHJEJ_01508 0.0 ydaB - - IQ - - - acyl-CoA ligase
HEIKHJEJ_01509 1e-127 ydaC - - Q - - - Methyltransferase domain
HEIKHJEJ_01510 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_01511 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HEIKHJEJ_01512 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEIKHJEJ_01513 6.13e-100 ydaG - - S - - - general stress protein
HEIKHJEJ_01514 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEIKHJEJ_01515 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HEIKHJEJ_01516 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HEIKHJEJ_01517 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEIKHJEJ_01518 8.17e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEIKHJEJ_01519 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HEIKHJEJ_01521 1.84e-34 - - - - - - - -
HEIKHJEJ_01522 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
HEIKHJEJ_01524 6.14e-53 - - - - - - - -
HEIKHJEJ_01525 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEIKHJEJ_01526 1.67e-42 ydaS - - S - - - membrane
HEIKHJEJ_01527 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HEIKHJEJ_01528 4.3e-190 ydbA - - P - - - EcsC protein family
HEIKHJEJ_01529 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
HEIKHJEJ_01530 2.17e-78 ydbB - - G - - - Cupin domain
HEIKHJEJ_01531 3.66e-82 ydbC - - S - - - Domain of unknown function (DUF4937
HEIKHJEJ_01532 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
HEIKHJEJ_01533 6.07e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEIKHJEJ_01534 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEIKHJEJ_01535 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HEIKHJEJ_01536 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEIKHJEJ_01537 5.38e-230 ydbI - - S - - - AI-2E family transporter
HEIKHJEJ_01538 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_01539 4.95e-158 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEIKHJEJ_01540 9.32e-70 ydbL - - - - - - -
HEIKHJEJ_01541 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
HEIKHJEJ_01542 1.49e-26 - - - S - - - Fur-regulated basic protein B
HEIKHJEJ_01543 2.1e-11 - - - S - - - Fur-regulated basic protein A
HEIKHJEJ_01544 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEIKHJEJ_01545 4.19e-75 ydbP - - CO - - - Thioredoxin
HEIKHJEJ_01546 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HEIKHJEJ_01547 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEIKHJEJ_01548 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEIKHJEJ_01549 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HEIKHJEJ_01550 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HEIKHJEJ_01551 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HEIKHJEJ_01552 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEIKHJEJ_01553 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HEIKHJEJ_01554 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEIKHJEJ_01555 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEIKHJEJ_01556 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEIKHJEJ_01557 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HEIKHJEJ_01558 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HEIKHJEJ_01559 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEIKHJEJ_01560 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HEIKHJEJ_01561 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HEIKHJEJ_01562 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEIKHJEJ_01563 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEIKHJEJ_01564 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HEIKHJEJ_01567 4.42e-105 ydcG - - S - - - EVE domain
HEIKHJEJ_01568 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_01569 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HEIKHJEJ_01570 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HEIKHJEJ_01578 5.14e-269 ydcL - - L - - - Belongs to the 'phage' integrase family
HEIKHJEJ_01579 1.65e-118 - - - E - - - IrrE N-terminal-like domain
HEIKHJEJ_01580 1.91e-81 - - - K - - - Transcriptional
HEIKHJEJ_01581 8.96e-24 - - - - - - - -
HEIKHJEJ_01582 1.35e-55 - - - - - - - -
HEIKHJEJ_01584 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
HEIKHJEJ_01585 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
HEIKHJEJ_01586 2.58e-254 nicK - - L ko:K07467 - ko00000 Replication initiation factor
HEIKHJEJ_01587 2.68e-23 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
HEIKHJEJ_01590 2.49e-63 yddA - - - - - - -
HEIKHJEJ_01591 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HEIKHJEJ_01592 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HEIKHJEJ_01593 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HEIKHJEJ_01594 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEIKHJEJ_01595 1.37e-217 alsR - - K - - - LysR substrate binding domain
HEIKHJEJ_01596 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEIKHJEJ_01597 4.33e-162 ywrJ - - - - - - -
HEIKHJEJ_01598 7.86e-162 cotB - - - ko:K06325 - ko00000 -
HEIKHJEJ_01599 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
HEIKHJEJ_01600 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEIKHJEJ_01601 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
HEIKHJEJ_01602 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HEIKHJEJ_01603 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HEIKHJEJ_01604 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HEIKHJEJ_01605 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HEIKHJEJ_01607 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
HEIKHJEJ_01608 4.73e-209 - - - K - - - Transcriptional regulator
HEIKHJEJ_01609 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEIKHJEJ_01611 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
HEIKHJEJ_01612 4.93e-95 ywqJ - - S - - - Pre-toxin TG
HEIKHJEJ_01613 1.3e-23 - - - - - - - -
HEIKHJEJ_01614 2.5e-26 - - - - - - - -
HEIKHJEJ_01615 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HEIKHJEJ_01616 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HEIKHJEJ_01618 1.45e-108 ywqG - - S - - - Domain of unknown function (DUF1963)
HEIKHJEJ_01619 1.3e-38 ywqG - - S - - - Domain of unknown function (DUF1963)
HEIKHJEJ_01620 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEIKHJEJ_01621 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HEIKHJEJ_01622 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HEIKHJEJ_01623 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HEIKHJEJ_01624 3.6e-25 - - - - - - - -
HEIKHJEJ_01625 0.0 ywqB - - S - - - SWIM zinc finger
HEIKHJEJ_01626 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEIKHJEJ_01627 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEIKHJEJ_01628 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEIKHJEJ_01629 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HEIKHJEJ_01630 2.79e-40 ywpG - - - - - - -
HEIKHJEJ_01631 3.59e-88 ywpF - - S - - - YwpF-like protein
HEIKHJEJ_01632 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HEIKHJEJ_01633 4.66e-186 ywpD - - T - - - Histidine kinase
HEIKHJEJ_01634 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEIKHJEJ_01635 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEIKHJEJ_01636 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HEIKHJEJ_01637 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HEIKHJEJ_01638 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HEIKHJEJ_01639 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HEIKHJEJ_01640 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HEIKHJEJ_01641 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HEIKHJEJ_01642 3.21e-268 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_01643 1.14e-309 ywoF - - P - - - Right handed beta helix region
HEIKHJEJ_01644 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HEIKHJEJ_01645 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
HEIKHJEJ_01646 3e-133 yjgF - - Q - - - Isochorismatase family
HEIKHJEJ_01647 7.16e-101 - - - - - - - -
HEIKHJEJ_01648 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HEIKHJEJ_01649 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HEIKHJEJ_01650 1.72e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HEIKHJEJ_01651 9.05e-93 ywnJ - - S - - - VanZ like family
HEIKHJEJ_01652 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HEIKHJEJ_01653 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HEIKHJEJ_01654 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
HEIKHJEJ_01655 6.7e-234 - - - M - - - NeuB family
HEIKHJEJ_01656 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
HEIKHJEJ_01657 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEIKHJEJ_01658 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HEIKHJEJ_01659 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HEIKHJEJ_01660 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HEIKHJEJ_01661 4.58e-85 ywnA - - K - - - Transcriptional regulator
HEIKHJEJ_01662 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEIKHJEJ_01663 6.21e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HEIKHJEJ_01664 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HEIKHJEJ_01665 2.15e-19 csbD - - K - - - CsbD-like
HEIKHJEJ_01666 3.22e-109 ywmF - - S - - - Peptidase M50
HEIKHJEJ_01667 2.18e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_01668 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEIKHJEJ_01669 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEIKHJEJ_01671 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEIKHJEJ_01672 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEIKHJEJ_01673 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HEIKHJEJ_01674 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEIKHJEJ_01675 6.59e-172 ywmB - - S - - - TATA-box binding
HEIKHJEJ_01676 4.54e-45 ywzB - - S - - - membrane
HEIKHJEJ_01677 2.92e-113 ywmA - - - - - - -
HEIKHJEJ_01678 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEIKHJEJ_01679 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEIKHJEJ_01680 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEIKHJEJ_01681 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEIKHJEJ_01682 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEIKHJEJ_01683 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEIKHJEJ_01684 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEIKHJEJ_01685 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEIKHJEJ_01686 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HEIKHJEJ_01687 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEIKHJEJ_01688 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEIKHJEJ_01689 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
HEIKHJEJ_01690 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HEIKHJEJ_01691 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEIKHJEJ_01692 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HEIKHJEJ_01693 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEIKHJEJ_01694 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HEIKHJEJ_01695 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HEIKHJEJ_01696 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEIKHJEJ_01698 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEIKHJEJ_01699 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEIKHJEJ_01700 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_01701 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEIKHJEJ_01702 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HEIKHJEJ_01703 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HEIKHJEJ_01704 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEIKHJEJ_01705 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HEIKHJEJ_01706 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEIKHJEJ_01707 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HEIKHJEJ_01708 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEIKHJEJ_01710 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEIKHJEJ_01711 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HEIKHJEJ_01712 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HEIKHJEJ_01713 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
HEIKHJEJ_01714 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEIKHJEJ_01715 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEIKHJEJ_01716 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
HEIKHJEJ_01717 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HEIKHJEJ_01718 5.54e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEIKHJEJ_01719 1.4e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEIKHJEJ_01720 5.49e-124 ywjB - - H - - - RibD C-terminal domain
HEIKHJEJ_01721 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEIKHJEJ_01722 9.8e-37 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEIKHJEJ_01723 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEIKHJEJ_01724 8.39e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HEIKHJEJ_01725 2.77e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HEIKHJEJ_01726 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HEIKHJEJ_01727 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEIKHJEJ_01728 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HEIKHJEJ_01729 1.84e-179 ywiC - - S - - - YwiC-like protein
HEIKHJEJ_01730 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HEIKHJEJ_01731 8.44e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HEIKHJEJ_01732 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEIKHJEJ_01733 5.42e-95 ywiB - - S - - - protein conserved in bacteria
HEIKHJEJ_01734 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HEIKHJEJ_01735 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HEIKHJEJ_01737 6.11e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEIKHJEJ_01738 1.09e-293 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HEIKHJEJ_01739 4.01e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HEIKHJEJ_01740 7.39e-312 - - - L - - - Peptidase, M16
HEIKHJEJ_01742 1.18e-315 ywhL - - CO - - - amine dehydrogenase activity
HEIKHJEJ_01743 1.04e-252 ywhK - - CO - - - amine dehydrogenase activity
HEIKHJEJ_01744 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HEIKHJEJ_01746 2.03e-84 - - - S - - - Aminoacyl-tRNA editing domain
HEIKHJEJ_01747 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HEIKHJEJ_01748 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEIKHJEJ_01749 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEIKHJEJ_01750 2.1e-64 - - - - - - - -
HEIKHJEJ_01751 1.92e-123 ywhD - - S - - - YwhD family
HEIKHJEJ_01752 3.29e-154 ywhC - - S - - - Peptidase family M50
HEIKHJEJ_01753 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HEIKHJEJ_01754 1.45e-93 ywhA - - K - - - Transcriptional regulator
HEIKHJEJ_01755 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEIKHJEJ_01757 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HEIKHJEJ_01758 1.1e-103 yffB - - K - - - Transcriptional regulator
HEIKHJEJ_01759 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HEIKHJEJ_01760 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HEIKHJEJ_01761 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HEIKHJEJ_01762 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HEIKHJEJ_01763 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HEIKHJEJ_01764 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEIKHJEJ_01765 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_01766 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HEIKHJEJ_01767 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HEIKHJEJ_01768 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HEIKHJEJ_01769 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HEIKHJEJ_01770 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HEIKHJEJ_01771 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEIKHJEJ_01772 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_01773 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEIKHJEJ_01774 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEIKHJEJ_01775 3.81e-275 ywfA - - EGP - - - -transporter
HEIKHJEJ_01776 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEIKHJEJ_01777 0.0 rocB - - E - - - arginine degradation protein
HEIKHJEJ_01778 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEIKHJEJ_01779 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEIKHJEJ_01780 2.14e-100 - - - - - - - -
HEIKHJEJ_01781 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HEIKHJEJ_01782 1.92e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEIKHJEJ_01783 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEIKHJEJ_01784 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEIKHJEJ_01785 5.73e-240 spsG - - M - - - Spore Coat
HEIKHJEJ_01786 1.09e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
HEIKHJEJ_01787 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HEIKHJEJ_01788 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HEIKHJEJ_01789 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HEIKHJEJ_01790 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HEIKHJEJ_01791 7.76e-185 spsA - - M - - - Spore Coat
HEIKHJEJ_01792 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEIKHJEJ_01793 1.59e-78 ywdK - - S - - - small membrane protein
HEIKHJEJ_01794 3.75e-303 ywdJ - - F - - - Xanthine uracil
HEIKHJEJ_01795 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HEIKHJEJ_01796 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEIKHJEJ_01797 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEIKHJEJ_01798 5.46e-191 ywdF - - S - - - Glycosyltransferase like family 2
HEIKHJEJ_01799 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEIKHJEJ_01800 6.19e-39 ywdA - - - - - - -
HEIKHJEJ_01801 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HEIKHJEJ_01802 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_01803 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HEIKHJEJ_01804 6.46e-112 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEIKHJEJ_01805 5e-63 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEIKHJEJ_01807 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEIKHJEJ_01808 2.83e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEIKHJEJ_01809 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HEIKHJEJ_01810 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEIKHJEJ_01811 3.69e-260 - - - S - - - Acetyltransferase
HEIKHJEJ_01812 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HEIKHJEJ_01813 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HEIKHJEJ_01814 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HEIKHJEJ_01815 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEIKHJEJ_01816 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEIKHJEJ_01817 5.11e-49 ydaS - - S - - - membrane
HEIKHJEJ_01818 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HEIKHJEJ_01819 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEIKHJEJ_01820 3.33e-77 gtcA - - S - - - GtrA-like protein
HEIKHJEJ_01821 1.98e-157 ywcC - - K - - - transcriptional regulator
HEIKHJEJ_01823 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
HEIKHJEJ_01824 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEIKHJEJ_01841 1.23e-182 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HEIKHJEJ_01842 1.58e-36 - - - - - - - -
HEIKHJEJ_01843 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HEIKHJEJ_01844 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEIKHJEJ_01846 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEIKHJEJ_01847 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEIKHJEJ_01848 2.82e-216 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HEIKHJEJ_01849 1.13e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEIKHJEJ_01850 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HEIKHJEJ_01852 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEIKHJEJ_01853 3.81e-100 ygaO - - - - - - -
HEIKHJEJ_01854 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_01856 8.77e-144 yhzB - - S - - - B3/4 domain
HEIKHJEJ_01857 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEIKHJEJ_01858 9.27e-224 yhbB - - S - - - Putative amidase domain
HEIKHJEJ_01859 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEIKHJEJ_01860 5.64e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
HEIKHJEJ_01861 3.77e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HEIKHJEJ_01862 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HEIKHJEJ_01863 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HEIKHJEJ_01864 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HEIKHJEJ_01865 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HEIKHJEJ_01866 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HEIKHJEJ_01867 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HEIKHJEJ_01868 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HEIKHJEJ_01869 3.95e-59 yhcC - - - - - - -
HEIKHJEJ_01870 2.06e-69 - - - - - - - -
HEIKHJEJ_01871 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_01872 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_01873 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_01874 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEIKHJEJ_01875 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HEIKHJEJ_01876 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEIKHJEJ_01877 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HEIKHJEJ_01878 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEIKHJEJ_01879 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HEIKHJEJ_01880 1.5e-81 - - - S - - - Immunity protein 70
HEIKHJEJ_01884 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
HEIKHJEJ_01886 4.39e-37 yddA - - - - - - -
HEIKHJEJ_01890 2.09e-103 - - - - - - - -
HEIKHJEJ_01891 7.6e-12 - - - S - - - Helix-turn-helix domain
HEIKHJEJ_01892 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
HEIKHJEJ_01893 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
HEIKHJEJ_01894 5.33e-85 - - - - - - - -
HEIKHJEJ_01895 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
HEIKHJEJ_01897 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
HEIKHJEJ_01898 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
HEIKHJEJ_01899 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
HEIKHJEJ_01901 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
HEIKHJEJ_01902 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HEIKHJEJ_01903 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEIKHJEJ_01904 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEIKHJEJ_01905 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HEIKHJEJ_01906 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HEIKHJEJ_01907 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_01908 6.31e-51 - - - - - - - -
HEIKHJEJ_01909 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEIKHJEJ_01910 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
HEIKHJEJ_01913 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HEIKHJEJ_01915 1.51e-18 cotW - - - ko:K06341 - ko00000 -
HEIKHJEJ_01916 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HEIKHJEJ_01917 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HEIKHJEJ_01918 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HEIKHJEJ_01919 2.09e-103 yjbX - - S - - - Spore coat protein
HEIKHJEJ_01920 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HEIKHJEJ_01921 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEIKHJEJ_01922 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEIKHJEJ_01923 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEIKHJEJ_01924 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HEIKHJEJ_01925 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HEIKHJEJ_01926 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HEIKHJEJ_01927 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEIKHJEJ_01928 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEIKHJEJ_01929 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEIKHJEJ_01930 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEIKHJEJ_01931 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEIKHJEJ_01932 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HEIKHJEJ_01933 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
HEIKHJEJ_01934 7.02e-128 yjbK - - S - - - protein conserved in bacteria
HEIKHJEJ_01935 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEIKHJEJ_01936 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HEIKHJEJ_01937 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HEIKHJEJ_01938 2.68e-28 - - - - - - - -
HEIKHJEJ_01939 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HEIKHJEJ_01940 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
HEIKHJEJ_01941 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEIKHJEJ_01942 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
HEIKHJEJ_01943 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEIKHJEJ_01944 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_01945 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
HEIKHJEJ_01946 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_01947 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_01948 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_01949 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_01950 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEIKHJEJ_01951 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HEIKHJEJ_01952 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
HEIKHJEJ_01953 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_01954 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEIKHJEJ_01955 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HEIKHJEJ_01956 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_01957 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_01958 3.86e-192 yjaZ - - O - - - Zn-dependent protease
HEIKHJEJ_01959 5.08e-301 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEIKHJEJ_01960 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEIKHJEJ_01961 3.48e-33 yjzB - - - - - - -
HEIKHJEJ_01962 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HEIKHJEJ_01963 3.04e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HEIKHJEJ_01964 5.2e-132 yjaV - - - - - - -
HEIKHJEJ_01965 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
HEIKHJEJ_01966 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HEIKHJEJ_01967 2.51e-39 yjzC - - S - - - YjzC-like protein
HEIKHJEJ_01968 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HEIKHJEJ_01969 0.000711 - - - - - - - -
HEIKHJEJ_01972 6.04e-78 - - - L - - - Phage integrase family
HEIKHJEJ_01973 7.89e-68 - - - M - - - ArpU family transcriptional regulator
HEIKHJEJ_01975 1.12e-07 - - - S - - - YopX protein
HEIKHJEJ_01977 6.17e-60 - - - S - - - dUTPase
HEIKHJEJ_01983 2.78e-08 - - - - - - - -
HEIKHJEJ_01986 1.76e-10 - - - - - - - -
HEIKHJEJ_01987 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HEIKHJEJ_01988 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HEIKHJEJ_01991 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HEIKHJEJ_01992 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
HEIKHJEJ_01995 5.28e-79 - - - - - - - -
HEIKHJEJ_01996 4.26e-43 - - - S - - - Phage integrase family
HEIKHJEJ_01997 2.09e-81 - - - S - - - Phage integrase family
HEIKHJEJ_01999 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEIKHJEJ_02000 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEIKHJEJ_02001 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HEIKHJEJ_02002 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HEIKHJEJ_02003 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HEIKHJEJ_02004 4.9e-48 yvzC - - K - - - transcriptional
HEIKHJEJ_02005 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HEIKHJEJ_02006 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_02007 3.85e-72 yvaP - - K - - - transcriptional
HEIKHJEJ_02008 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_02009 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEIKHJEJ_02010 1.13e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEIKHJEJ_02011 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEIKHJEJ_02012 1.73e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEIKHJEJ_02013 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HEIKHJEJ_02014 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEIKHJEJ_02015 6.08e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEIKHJEJ_02016 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HEIKHJEJ_02017 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEIKHJEJ_02018 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HEIKHJEJ_02019 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HEIKHJEJ_02020 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
HEIKHJEJ_02021 2.66e-155 yvbI - - M - - - Membrane
HEIKHJEJ_02022 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HEIKHJEJ_02023 1.18e-97 yvbK - - K - - - acetyltransferase
HEIKHJEJ_02024 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEIKHJEJ_02025 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HEIKHJEJ_02026 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEIKHJEJ_02027 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HEIKHJEJ_02028 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEIKHJEJ_02029 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEIKHJEJ_02030 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_02031 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HEIKHJEJ_02032 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEIKHJEJ_02033 1.99e-205 yvbU - - K - - - Transcriptional regulator
HEIKHJEJ_02034 5.59e-198 yvbV - - EG - - - EamA-like transporter family
HEIKHJEJ_02035 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_02036 2.7e-187 - - - S - - - Glycosyl hydrolase
HEIKHJEJ_02037 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEIKHJEJ_02038 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEIKHJEJ_02039 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEIKHJEJ_02040 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_02041 5.39e-252 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_02042 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HEIKHJEJ_02043 5.7e-207 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HEIKHJEJ_02044 8.25e-33 - 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 AAA domain
HEIKHJEJ_02045 3.23e-178 - - - M - - - -acetyltransferase
HEIKHJEJ_02046 1.15e-66 - - - S - - - ASCH
HEIKHJEJ_02047 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HEIKHJEJ_02048 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HEIKHJEJ_02049 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HEIKHJEJ_02050 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HEIKHJEJ_02051 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HEIKHJEJ_02052 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HEIKHJEJ_02053 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HEIKHJEJ_02054 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_02055 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HEIKHJEJ_02056 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEIKHJEJ_02057 7.05e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEIKHJEJ_02058 5.69e-44 yvfG - - S - - - YvfG protein
HEIKHJEJ_02059 5.09e-239 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HEIKHJEJ_02060 1.5e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HEIKHJEJ_02061 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HEIKHJEJ_02062 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEIKHJEJ_02063 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_02064 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEIKHJEJ_02065 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HEIKHJEJ_02066 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HEIKHJEJ_02067 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HEIKHJEJ_02068 1.19e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEIKHJEJ_02069 6.94e-199 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEIKHJEJ_02070 2.49e-278 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HEIKHJEJ_02071 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HEIKHJEJ_02072 1.6e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HEIKHJEJ_02073 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HEIKHJEJ_02074 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HEIKHJEJ_02075 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HEIKHJEJ_02077 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HEIKHJEJ_02078 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
HEIKHJEJ_02079 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
HEIKHJEJ_02080 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HEIKHJEJ_02081 2.17e-224 pbpE - - V - - - Beta-lactamase
HEIKHJEJ_02082 3.77e-79 pbpE - - V - - - Beta-lactamase
HEIKHJEJ_02083 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HEIKHJEJ_02084 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HEIKHJEJ_02085 0.0 ybeC - - E - - - amino acid
HEIKHJEJ_02086 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
HEIKHJEJ_02087 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HEIKHJEJ_02088 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HEIKHJEJ_02089 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
HEIKHJEJ_02090 3.28e-29 - - - K - - - Helix-turn-helix
HEIKHJEJ_02092 2.94e-166 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
HEIKHJEJ_02093 1.27e-83 - - - - - - - -
HEIKHJEJ_02095 7.35e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
HEIKHJEJ_02096 2.24e-192 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_02097 1.85e-40 - - - S - - - BhlA holin family
HEIKHJEJ_02099 1.42e-25 - - - - - - - -
HEIKHJEJ_02100 3.21e-70 ydeH - - - - - - -
HEIKHJEJ_02101 1.16e-234 ydeG - - EGP - - - Major facilitator superfamily
HEIKHJEJ_02102 3.74e-24 ydeG - - EGP - - - Major facilitator superfamily
HEIKHJEJ_02103 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_02104 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HEIKHJEJ_02105 5.69e-105 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEIKHJEJ_02106 4.71e-83 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEIKHJEJ_02107 2.44e-210 - - - K - - - AraC-like ligand binding domain
HEIKHJEJ_02108 5.97e-174 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEIKHJEJ_02109 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HEIKHJEJ_02110 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HEIKHJEJ_02111 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
HEIKHJEJ_02115 2.98e-53 - - - - - - - -
HEIKHJEJ_02116 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HEIKHJEJ_02117 1.35e-169 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEIKHJEJ_02118 9.99e-59 - - - - - - - -
HEIKHJEJ_02119 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_02120 9.13e-135 ywqM - - K - - - Transcriptional regulator
HEIKHJEJ_02121 4.46e-153 - - - E - - - amino acid
HEIKHJEJ_02122 1.74e-95 - - - T - - - NACHT domain
HEIKHJEJ_02123 3.75e-30 - - - - - - - -
HEIKHJEJ_02124 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEIKHJEJ_02125 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_02126 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HEIKHJEJ_02127 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEIKHJEJ_02129 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HEIKHJEJ_02130 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HEIKHJEJ_02131 7.68e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HEIKHJEJ_02132 2.91e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HEIKHJEJ_02133 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEIKHJEJ_02135 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02138 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
HEIKHJEJ_02142 1.23e-151 - - - K - - - Transcriptional regulator
HEIKHJEJ_02143 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HEIKHJEJ_02144 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEIKHJEJ_02145 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_02146 1.24e-198 degV - - S - - - protein conserved in bacteria
HEIKHJEJ_02147 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEIKHJEJ_02148 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HEIKHJEJ_02149 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HEIKHJEJ_02150 3.05e-95 yvyF - - S - - - flagellar protein
HEIKHJEJ_02151 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HEIKHJEJ_02152 7.06e-102 yvyG - - NOU - - - FlgN protein
HEIKHJEJ_02153 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HEIKHJEJ_02154 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HEIKHJEJ_02155 6.92e-92 yviE - - - - - - -
HEIKHJEJ_02156 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEIKHJEJ_02157 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEIKHJEJ_02158 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEIKHJEJ_02159 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HEIKHJEJ_02160 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEIKHJEJ_02161 1.48e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HEIKHJEJ_02162 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HEIKHJEJ_02163 2.46e-67 - - - - - - - -
HEIKHJEJ_02164 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEIKHJEJ_02165 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEIKHJEJ_02166 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEIKHJEJ_02167 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEIKHJEJ_02168 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HEIKHJEJ_02169 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HEIKHJEJ_02170 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEIKHJEJ_02171 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEIKHJEJ_02172 1.38e-73 swrA - - S - - - Swarming motility protein
HEIKHJEJ_02173 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEIKHJEJ_02174 3.03e-295 yvkA - - P - - - -transporter
HEIKHJEJ_02175 1.43e-131 yvkB - - K - - - Transcriptional regulator
HEIKHJEJ_02176 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HEIKHJEJ_02177 2.54e-42 csbA - - S - - - protein conserved in bacteria
HEIKHJEJ_02178 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEIKHJEJ_02179 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEIKHJEJ_02180 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEIKHJEJ_02181 2.25e-45 yvkN - - - - - - -
HEIKHJEJ_02182 8.09e-65 yvlA - - - - - - -
HEIKHJEJ_02183 5.54e-219 yvlB - - S - - - Putative adhesin
HEIKHJEJ_02184 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HEIKHJEJ_02185 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HEIKHJEJ_02187 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HEIKHJEJ_02188 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02189 4.66e-213 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_02190 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HEIKHJEJ_02191 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02192 2.69e-294 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEIKHJEJ_02193 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_02194 1.3e-238 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HEIKHJEJ_02195 1.56e-178 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02196 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HEIKHJEJ_02197 5.75e-78 yttA - - S - - - Pfam Transposase IS66
HEIKHJEJ_02198 4.05e-267 yttB - - EGP - - - Major facilitator superfamily
HEIKHJEJ_02199 1.49e-180 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEIKHJEJ_02200 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HEIKHJEJ_02201 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEIKHJEJ_02202 1.22e-68 ytwF - - P - - - Sulfurtransferase
HEIKHJEJ_02203 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEIKHJEJ_02204 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HEIKHJEJ_02205 1.77e-198 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_02206 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEIKHJEJ_02207 2.08e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_02208 1.67e-221 - - - S - - - Acetyl xylan esterase (AXE1)
HEIKHJEJ_02209 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEIKHJEJ_02210 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEIKHJEJ_02211 2.83e-256 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEIKHJEJ_02212 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEIKHJEJ_02213 1.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEIKHJEJ_02214 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEIKHJEJ_02215 1.05e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HEIKHJEJ_02216 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HEIKHJEJ_02217 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HEIKHJEJ_02218 5.52e-276 ytdP - - K - - - Transcriptional regulator
HEIKHJEJ_02219 1.36e-202 ytdP - - K - - - Transcriptional regulator
HEIKHJEJ_02220 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HEIKHJEJ_02221 4.8e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HEIKHJEJ_02222 2.27e-92 yteS - - G - - - transport
HEIKHJEJ_02223 1.83e-251 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HEIKHJEJ_02224 9.57e-98 yteU - - S - - - Integral membrane protein
HEIKHJEJ_02225 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HEIKHJEJ_02226 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HEIKHJEJ_02227 1.16e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HEIKHJEJ_02228 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_02229 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEIKHJEJ_02230 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HEIKHJEJ_02231 4.65e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEIKHJEJ_02232 2.89e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HEIKHJEJ_02233 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HEIKHJEJ_02234 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HEIKHJEJ_02235 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEIKHJEJ_02236 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEIKHJEJ_02237 4.92e-212 ytlQ - - - - - - -
HEIKHJEJ_02238 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HEIKHJEJ_02239 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HEIKHJEJ_02240 3.02e-192 ytmP - - M - - - Phosphotransferase
HEIKHJEJ_02241 9.51e-61 ytzH - - S - - - YtzH-like protein
HEIKHJEJ_02242 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEIKHJEJ_02243 3.18e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEIKHJEJ_02244 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HEIKHJEJ_02245 6.75e-67 ytzB - - S - - - small secreted protein
HEIKHJEJ_02246 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HEIKHJEJ_02247 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HEIKHJEJ_02248 3.17e-75 ytpP - - CO - - - Thioredoxin
HEIKHJEJ_02249 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HEIKHJEJ_02250 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEIKHJEJ_02251 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEIKHJEJ_02252 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEIKHJEJ_02253 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEIKHJEJ_02254 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HEIKHJEJ_02255 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HEIKHJEJ_02256 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEIKHJEJ_02257 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HEIKHJEJ_02258 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HEIKHJEJ_02259 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HEIKHJEJ_02260 1.79e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HEIKHJEJ_02261 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HEIKHJEJ_02262 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEIKHJEJ_02263 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEIKHJEJ_02264 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEIKHJEJ_02266 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEIKHJEJ_02267 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HEIKHJEJ_02268 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HEIKHJEJ_02269 9.83e-141 yttP - - K - - - Transcriptional regulator
HEIKHJEJ_02270 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEIKHJEJ_02271 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEIKHJEJ_02272 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEIKHJEJ_02273 2.74e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEIKHJEJ_02274 8.89e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEIKHJEJ_02275 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HEIKHJEJ_02276 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEIKHJEJ_02277 0.0 ytcJ - - S - - - amidohydrolase
HEIKHJEJ_02278 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEIKHJEJ_02279 4.62e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HEIKHJEJ_02280 2.36e-111 yteJ - - S - - - RDD family
HEIKHJEJ_02281 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
HEIKHJEJ_02282 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
HEIKHJEJ_02283 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEIKHJEJ_02284 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HEIKHJEJ_02285 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEIKHJEJ_02286 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HEIKHJEJ_02287 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEIKHJEJ_02288 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HEIKHJEJ_02290 3.28e-181 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_02291 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HEIKHJEJ_02292 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
HEIKHJEJ_02293 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HEIKHJEJ_02294 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HEIKHJEJ_02296 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HEIKHJEJ_02297 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HEIKHJEJ_02298 4.3e-124 yrhH - - Q - - - methyltransferase
HEIKHJEJ_02299 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HEIKHJEJ_02300 2.35e-201 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HEIKHJEJ_02301 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HEIKHJEJ_02302 6.32e-59 yrhK - - S - - - YrhK-like protein
HEIKHJEJ_02303 3.76e-287 oatA - - I - - - Acyltransferase family
HEIKHJEJ_02304 2.18e-84 oatA - - I - - - Acyltransferase family
HEIKHJEJ_02305 2.88e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
HEIKHJEJ_02306 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_02307 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HEIKHJEJ_02308 5.63e-137 yrhP - - E - - - LysE type translocator
HEIKHJEJ_02309 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_02310 0.0 levR - - K - - - PTS system fructose IIA component
HEIKHJEJ_02311 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEIKHJEJ_02312 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HEIKHJEJ_02313 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HEIKHJEJ_02314 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HEIKHJEJ_02315 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HEIKHJEJ_02316 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HEIKHJEJ_02317 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HEIKHJEJ_02318 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HEIKHJEJ_02319 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HEIKHJEJ_02320 4.9e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
HEIKHJEJ_02321 6.11e-36 yraE - - - ko:K06440 - ko00000 -
HEIKHJEJ_02322 3.71e-283 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEIKHJEJ_02323 9.61e-84 yraF - - M - - - Spore coat protein
HEIKHJEJ_02324 4.04e-48 yraG - - - ko:K06440 - ko00000 -
HEIKHJEJ_02325 1.1e-85 - - - E - - - Glyoxalase-like domain
HEIKHJEJ_02326 1.05e-81 - - - T - - - sh3 domain protein
HEIKHJEJ_02327 6.61e-80 - - - T - - - sh3 domain protein
HEIKHJEJ_02328 1.05e-178 - - - S - - - Alpha beta hydrolase
HEIKHJEJ_02329 8.42e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_02330 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEIKHJEJ_02331 5.72e-238 yrpG - - C - - - Aldo/keto reductase family
HEIKHJEJ_02332 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_02333 6.26e-168 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HEIKHJEJ_02335 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
HEIKHJEJ_02336 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEIKHJEJ_02337 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEIKHJEJ_02338 1.48e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
HEIKHJEJ_02339 2.01e-118 yrdA - - S - - - DinB family
HEIKHJEJ_02341 1.09e-73 - - - S - - - Protein of unknown function (DUF2568)
HEIKHJEJ_02342 7.38e-131 yrdC - - Q - - - Isochorismatase family
HEIKHJEJ_02344 1.16e-284 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEIKHJEJ_02345 3.92e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
HEIKHJEJ_02346 4.45e-99 bkdR - - K - - - helix_turn_helix ASNC type
HEIKHJEJ_02347 2.1e-117 azlC - - E - - - AzlC protein
HEIKHJEJ_02348 2.79e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
HEIKHJEJ_02349 9.63e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEIKHJEJ_02351 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
HEIKHJEJ_02352 5e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
HEIKHJEJ_02353 1.4e-203 - - - K - - - Transcriptional regulator
HEIKHJEJ_02354 3.17e-212 yrdR - - EG - - - EamA-like transporter family
HEIKHJEJ_02355 2.45e-23 - - - S - - - YrzO-like protein
HEIKHJEJ_02356 6.17e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEIKHJEJ_02357 8.79e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HEIKHJEJ_02358 1.4e-264 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_02359 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HEIKHJEJ_02362 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
HEIKHJEJ_02365 2.43e-14 - - - - - - - -
HEIKHJEJ_02366 5.08e-26 xkdM - - S - - - Phage tail tube protein
HEIKHJEJ_02368 4.85e-182 - - - Q - - - ubiE/COQ5 methyltransferase family
HEIKHJEJ_02369 8.95e-225 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HEIKHJEJ_02370 7.75e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HEIKHJEJ_02371 1.29e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HEIKHJEJ_02372 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HEIKHJEJ_02373 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEIKHJEJ_02374 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEIKHJEJ_02375 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HEIKHJEJ_02376 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
HEIKHJEJ_02377 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HEIKHJEJ_02378 7.22e-191 ycgS - - I - - - alpha/beta hydrolase fold
HEIKHJEJ_02379 9.55e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HEIKHJEJ_02380 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HEIKHJEJ_02381 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HEIKHJEJ_02382 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEIKHJEJ_02383 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEIKHJEJ_02384 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HEIKHJEJ_02385 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HEIKHJEJ_02386 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HEIKHJEJ_02387 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
HEIKHJEJ_02388 2.72e-141 yciC - - S - - - GTPases (G3E family)
HEIKHJEJ_02389 2.26e-123 yciC - - S - - - GTPases (G3E family)
HEIKHJEJ_02390 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEIKHJEJ_02391 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEIKHJEJ_02394 1.11e-96 yckC - - S - - - membrane
HEIKHJEJ_02395 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
HEIKHJEJ_02396 1.06e-57 - - - K - - - MarR family
HEIKHJEJ_02397 2.49e-27 - - - - - - - -
HEIKHJEJ_02398 2.13e-113 - - - S - - - AAA domain
HEIKHJEJ_02399 2.42e-27 - - - S - - - AAA domain
HEIKHJEJ_02400 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEIKHJEJ_02401 3.36e-91 nin - - S - - - Competence protein J (ComJ)
HEIKHJEJ_02402 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
HEIKHJEJ_02403 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_02404 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_02405 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HEIKHJEJ_02406 6.57e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HEIKHJEJ_02407 6.05e-86 hxlR - - K - - - transcriptional
HEIKHJEJ_02408 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_02409 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_02410 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEIKHJEJ_02411 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HEIKHJEJ_02412 5.99e-286 - - - EGP - - - Major Facilitator Superfamily
HEIKHJEJ_02413 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEIKHJEJ_02415 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEIKHJEJ_02416 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HEIKHJEJ_02417 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
HEIKHJEJ_02418 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEIKHJEJ_02420 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HEIKHJEJ_02421 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
HEIKHJEJ_02422 1.13e-29 yjfB - - S - - - Putative motility protein
HEIKHJEJ_02423 9.97e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HEIKHJEJ_02424 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HEIKHJEJ_02425 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
HEIKHJEJ_02426 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HEIKHJEJ_02427 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HEIKHJEJ_02428 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HEIKHJEJ_02430 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HEIKHJEJ_02432 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HEIKHJEJ_02433 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEIKHJEJ_02434 1.11e-41 - - - - - - - -
HEIKHJEJ_02435 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HEIKHJEJ_02436 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HEIKHJEJ_02437 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEIKHJEJ_02438 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HEIKHJEJ_02439 1.26e-20 yjlB - - S - - - Cupin domain
HEIKHJEJ_02440 1.16e-55 yjlB - - S - - - Cupin domain
HEIKHJEJ_02441 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HEIKHJEJ_02442 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEIKHJEJ_02443 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEIKHJEJ_02444 1.81e-315 - - - G ko:K03292 - ko00000 symporter YjmB
HEIKHJEJ_02445 8.48e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HEIKHJEJ_02446 3.22e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HEIKHJEJ_02447 2.65e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HEIKHJEJ_02448 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_02449 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HEIKHJEJ_02450 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HEIKHJEJ_02451 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HEIKHJEJ_02452 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HEIKHJEJ_02453 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HEIKHJEJ_02454 2.71e-103 yjoA - - S - - - DinB family
HEIKHJEJ_02455 8.62e-269 VCP - - O - - - AAA domain (dynein-related subfamily)
HEIKHJEJ_02456 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
HEIKHJEJ_02457 3.19e-266 - - - EGP - - - Transmembrane secretion effector
HEIKHJEJ_02458 4.83e-257 yhjN - - S ko:K07120 - ko00000 membrane
HEIKHJEJ_02459 5.09e-238 yhjM - - K - - - Transcriptional regulator
HEIKHJEJ_02460 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HEIKHJEJ_02461 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HEIKHJEJ_02462 2.69e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEIKHJEJ_02463 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HEIKHJEJ_02466 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_02467 0.0 yhjG - - CH - - - FAD binding domain
HEIKHJEJ_02468 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEIKHJEJ_02469 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
HEIKHJEJ_02470 4.13e-78 yhjD - - - - - - -
HEIKHJEJ_02471 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HEIKHJEJ_02472 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEIKHJEJ_02473 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
HEIKHJEJ_02474 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEIKHJEJ_02475 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HEIKHJEJ_02476 9.84e-45 yhzC - - S - - - IDEAL
HEIKHJEJ_02477 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_02478 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HEIKHJEJ_02479 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HEIKHJEJ_02480 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HEIKHJEJ_02481 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HEIKHJEJ_02482 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEIKHJEJ_02483 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HEIKHJEJ_02484 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEIKHJEJ_02485 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HEIKHJEJ_02486 1.53e-220 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEIKHJEJ_02487 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HEIKHJEJ_02488 1.47e-100 - - - K - - - acetyltransferase
HEIKHJEJ_02489 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEIKHJEJ_02490 9.64e-308 yhfN - - O - - - Peptidase M48
HEIKHJEJ_02491 2.28e-84 yhfM - - - - - - -
HEIKHJEJ_02492 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HEIKHJEJ_02493 2.13e-143 yhfK - - GM - - - NmrA-like family
HEIKHJEJ_02494 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEIKHJEJ_02495 9.84e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEIKHJEJ_02496 2.76e-288 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEIKHJEJ_02497 1.79e-92 - - - S - - - ASCH
HEIKHJEJ_02498 1.55e-252 yhfE - - G - - - peptidase M42
HEIKHJEJ_02499 2.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HEIKHJEJ_02500 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEIKHJEJ_02501 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HEIKHJEJ_02502 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_02503 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEIKHJEJ_02504 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HEIKHJEJ_02505 6.13e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEIKHJEJ_02506 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEIKHJEJ_02507 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HEIKHJEJ_02508 1e-44 - - - C - - - Rubrerythrin
HEIKHJEJ_02509 5.44e-312 yhfA - - C - - - membrane
HEIKHJEJ_02510 8.54e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEIKHJEJ_02511 9.67e-160 ecsC - - S - - - EcsC protein family
HEIKHJEJ_02512 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEIKHJEJ_02513 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HEIKHJEJ_02514 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEIKHJEJ_02515 7.5e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEIKHJEJ_02516 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HEIKHJEJ_02517 9.66e-30 - - - - - - - -
HEIKHJEJ_02518 1.74e-54 yhaH - - S - - - YtxH-like protein
HEIKHJEJ_02519 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HEIKHJEJ_02520 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
HEIKHJEJ_02521 5.71e-116 yhaK - - S - - - Putative zincin peptidase
HEIKHJEJ_02522 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEIKHJEJ_02523 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HEIKHJEJ_02524 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HEIKHJEJ_02525 0.0 yhaN - - L - - - AAA domain
HEIKHJEJ_02526 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HEIKHJEJ_02527 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HEIKHJEJ_02528 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02529 1.89e-35 - - - S - - - YhzD-like protein
HEIKHJEJ_02530 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
HEIKHJEJ_02532 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HEIKHJEJ_02533 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HEIKHJEJ_02534 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HEIKHJEJ_02535 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HEIKHJEJ_02536 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
HEIKHJEJ_02537 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
HEIKHJEJ_02538 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HEIKHJEJ_02539 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
HEIKHJEJ_02540 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
HEIKHJEJ_02541 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HEIKHJEJ_02542 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HEIKHJEJ_02543 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEIKHJEJ_02544 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_02545 1.01e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEIKHJEJ_02546 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HEIKHJEJ_02548 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEIKHJEJ_02549 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HEIKHJEJ_02550 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HEIKHJEJ_02551 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HEIKHJEJ_02552 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HEIKHJEJ_02553 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HEIKHJEJ_02554 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_02555 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HEIKHJEJ_02556 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HEIKHJEJ_02557 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEIKHJEJ_02558 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_02559 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HEIKHJEJ_02560 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HEIKHJEJ_02561 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HEIKHJEJ_02562 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HEIKHJEJ_02563 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HEIKHJEJ_02564 4.05e-215 eamA1 - - EG - - - spore germination
HEIKHJEJ_02565 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_02566 4.37e-214 ycbM - - T - - - Histidine kinase
HEIKHJEJ_02567 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02568 1.73e-149 - - - S - - - ABC-2 family transporter protein
HEIKHJEJ_02569 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
HEIKHJEJ_02570 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HEIKHJEJ_02571 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
HEIKHJEJ_02572 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HEIKHJEJ_02573 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEIKHJEJ_02574 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEIKHJEJ_02575 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEIKHJEJ_02576 4.66e-257 ycbU - - E - - - Selenocysteine lyase
HEIKHJEJ_02577 4.75e-307 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HEIKHJEJ_02578 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HEIKHJEJ_02579 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEIKHJEJ_02580 5.69e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEIKHJEJ_02581 4.32e-78 - - - S - - - RDD family
HEIKHJEJ_02582 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
HEIKHJEJ_02583 4.03e-156 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEIKHJEJ_02584 1.77e-43 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEIKHJEJ_02585 1.62e-161 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEIKHJEJ_02586 1.42e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEIKHJEJ_02587 2.86e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEIKHJEJ_02588 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_02589 3.94e-221 yccK - - C - - - Aldo keto reductase
HEIKHJEJ_02590 3.53e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
HEIKHJEJ_02591 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_02592 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_02593 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HEIKHJEJ_02594 4.37e-182 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_02595 2.93e-45 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_02596 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HEIKHJEJ_02597 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEIKHJEJ_02598 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEIKHJEJ_02599 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEIKHJEJ_02600 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEIKHJEJ_02601 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEIKHJEJ_02602 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEIKHJEJ_02603 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HEIKHJEJ_02604 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HEIKHJEJ_02605 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HEIKHJEJ_02606 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HEIKHJEJ_02607 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HEIKHJEJ_02608 2.96e-245 yceH - - P - - - Belongs to the TelA family
HEIKHJEJ_02609 1.59e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HEIKHJEJ_02610 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HEIKHJEJ_02611 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEIKHJEJ_02612 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_02613 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_02614 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEIKHJEJ_02615 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HEIKHJEJ_02616 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_02617 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HEIKHJEJ_02618 1.41e-119 yisT - - S - - - DinB family
HEIKHJEJ_02619 2.11e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HEIKHJEJ_02620 5.88e-232 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEIKHJEJ_02621 1.16e-206 yisR - - K - - - Transcriptional regulator
HEIKHJEJ_02622 7.14e-311 yisQ - - V - - - Mate efflux family protein
HEIKHJEJ_02623 4.02e-151 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HEIKHJEJ_02624 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEIKHJEJ_02625 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
HEIKHJEJ_02626 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEIKHJEJ_02627 1.44e-74 yisL - - S - - - UPF0344 protein
HEIKHJEJ_02628 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEIKHJEJ_02629 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
HEIKHJEJ_02630 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HEIKHJEJ_02631 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HEIKHJEJ_02632 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HEIKHJEJ_02633 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HEIKHJEJ_02634 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HEIKHJEJ_02635 3.92e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HEIKHJEJ_02636 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HEIKHJEJ_02637 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
HEIKHJEJ_02638 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HEIKHJEJ_02639 1.34e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEIKHJEJ_02640 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEIKHJEJ_02641 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HEIKHJEJ_02642 9.3e-102 yhjR - - S - - - Rubrerythrin
HEIKHJEJ_02643 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEIKHJEJ_02644 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEIKHJEJ_02645 1.81e-41 yazB - - K - - - transcriptional
HEIKHJEJ_02646 7.57e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEIKHJEJ_02647 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEIKHJEJ_02648 3.19e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEIKHJEJ_02649 1.32e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HEIKHJEJ_02650 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HEIKHJEJ_02651 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEIKHJEJ_02652 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEIKHJEJ_02653 4.17e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HEIKHJEJ_02654 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEIKHJEJ_02655 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEIKHJEJ_02656 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEIKHJEJ_02657 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEIKHJEJ_02658 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEIKHJEJ_02659 3.83e-233 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEIKHJEJ_02660 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HEIKHJEJ_02661 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HEIKHJEJ_02664 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HEIKHJEJ_02665 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HEIKHJEJ_02666 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
HEIKHJEJ_02667 1.91e-66 yabP - - S - - - Sporulation protein YabP
HEIKHJEJ_02668 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEIKHJEJ_02669 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEIKHJEJ_02670 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_02671 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HEIKHJEJ_02672 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEIKHJEJ_02673 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HEIKHJEJ_02674 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEIKHJEJ_02675 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEIKHJEJ_02676 3.51e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEIKHJEJ_02677 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEIKHJEJ_02678 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEIKHJEJ_02679 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HEIKHJEJ_02680 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HEIKHJEJ_02681 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEIKHJEJ_02682 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HEIKHJEJ_02683 5.32e-53 veg - - S - - - protein conserved in bacteria
HEIKHJEJ_02684 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HEIKHJEJ_02685 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEIKHJEJ_02686 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEIKHJEJ_02687 1.91e-283 yabE - - T - - - protein conserved in bacteria
HEIKHJEJ_02688 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HEIKHJEJ_02689 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEIKHJEJ_02690 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HEIKHJEJ_02691 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEIKHJEJ_02692 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HEIKHJEJ_02693 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HEIKHJEJ_02694 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HEIKHJEJ_02695 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
HEIKHJEJ_02696 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEIKHJEJ_02697 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HEIKHJEJ_02698 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
HEIKHJEJ_02699 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEIKHJEJ_02700 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HEIKHJEJ_02701 1.19e-258 yaaN - - P - - - Belongs to the TelA family
HEIKHJEJ_02702 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEIKHJEJ_02703 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HEIKHJEJ_02705 7.14e-75 eag - - - - - - -
HEIKHJEJ_02706 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HEIKHJEJ_02707 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HEIKHJEJ_02708 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HEIKHJEJ_02709 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HEIKHJEJ_02710 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HEIKHJEJ_02711 1.94e-226 ykvI - - S - - - membrane
HEIKHJEJ_02712 4.34e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEIKHJEJ_02713 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HEIKHJEJ_02714 1.69e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEIKHJEJ_02715 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEIKHJEJ_02716 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
HEIKHJEJ_02717 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HEIKHJEJ_02718 2.6e-39 - - - - - - - -
HEIKHJEJ_02719 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HEIKHJEJ_02720 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEIKHJEJ_02721 2.76e-115 stoA - - CO - - - thiol-disulfide
HEIKHJEJ_02722 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HEIKHJEJ_02723 3.99e-09 - - - - - - - -
HEIKHJEJ_02724 2.74e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HEIKHJEJ_02725 2.69e-229 ykvZ - - K - - - Transcriptional regulator
HEIKHJEJ_02727 1.39e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HEIKHJEJ_02728 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_02729 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HEIKHJEJ_02730 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEIKHJEJ_02731 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_02732 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HEIKHJEJ_02733 1.86e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_02734 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HEIKHJEJ_02735 6.67e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEIKHJEJ_02736 9.46e-198 yknT - - - ko:K06437 - ko00000 -
HEIKHJEJ_02737 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEIKHJEJ_02738 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEIKHJEJ_02739 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HEIKHJEJ_02740 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HEIKHJEJ_02741 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HEIKHJEJ_02742 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEIKHJEJ_02743 5.2e-260 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_02744 1.25e-95 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_02745 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_02746 1.31e-150 yknW - - S - - - Yip1 domain
HEIKHJEJ_02747 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEIKHJEJ_02748 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_02749 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HEIKHJEJ_02750 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_02751 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HEIKHJEJ_02752 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEIKHJEJ_02753 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEIKHJEJ_02754 5.43e-52 ykoA - - - - - - -
HEIKHJEJ_02755 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEIKHJEJ_02756 3.74e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEIKHJEJ_02757 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEIKHJEJ_02758 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HEIKHJEJ_02759 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HEIKHJEJ_02760 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HEIKHJEJ_02761 4.22e-305 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HEIKHJEJ_02762 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HEIKHJEJ_02763 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HEIKHJEJ_02764 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEIKHJEJ_02765 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEIKHJEJ_02766 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HEIKHJEJ_02767 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
HEIKHJEJ_02768 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEIKHJEJ_02769 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEIKHJEJ_02770 6.41e-52 ykyA - - L - - - Putative cell-wall binding lipoprotein
HEIKHJEJ_02771 6.37e-86 ykyA - - L - - - Putative cell-wall binding lipoprotein
HEIKHJEJ_02772 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEIKHJEJ_02773 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEIKHJEJ_02774 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEIKHJEJ_02775 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEIKHJEJ_02776 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HEIKHJEJ_02777 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HEIKHJEJ_02778 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
HEIKHJEJ_02779 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
HEIKHJEJ_02780 4.48e-35 ykzI - - - - - - -
HEIKHJEJ_02781 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HEIKHJEJ_02782 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
HEIKHJEJ_02783 0.0 - - - - - - - -
HEIKHJEJ_02784 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HEIKHJEJ_02786 0.0 - - - D - - - Phage tail tape measure protein
HEIKHJEJ_02789 1.46e-33 - - - - - - - -
HEIKHJEJ_02791 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HEIKHJEJ_02792 8.17e-38 - - - S - - - Phage head-tail joining protein
HEIKHJEJ_02794 5.45e-13 - - - - - - - -
HEIKHJEJ_02795 1.64e-161 - - - S - - - capsid protein
HEIKHJEJ_02796 3.96e-94 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HEIKHJEJ_02797 3.12e-215 - - - S - - - portal protein
HEIKHJEJ_02799 0.0 terL - - S - - - Terminase
HEIKHJEJ_02800 1.34e-77 - - - L - - - Terminase, small subunit
HEIKHJEJ_02804 2.62e-78 - - - - - - - -
HEIKHJEJ_02806 1.06e-106 - - - - - - - -
HEIKHJEJ_02807 3.14e-121 - - - S - - - nuclease activity
HEIKHJEJ_02808 3.9e-85 - - - - - - - -
HEIKHJEJ_02809 0.0 - - - S - - - hydrolase activity
HEIKHJEJ_02810 3.5e-97 - - - S - - - Protein of unknown function (DUF669)
HEIKHJEJ_02811 1.15e-07 - - - - - - - -
HEIKHJEJ_02812 6.48e-216 - - - S - - - AAA domain
HEIKHJEJ_02813 5.36e-120 - - - S - - - DNA protection
HEIKHJEJ_02815 3.42e-26 - - - S - - - Uncharacterized protein YqaH
HEIKHJEJ_02817 4.75e-28 - - - - - - - -
HEIKHJEJ_02818 7.74e-65 - - - S - - - Phage antirepressor protein KilAC domain
HEIKHJEJ_02820 3.93e-09 - - - K - - - Helix-turn-helix
HEIKHJEJ_02821 1.4e-59 - - - CE - - - IrrE N-terminal-like domain
HEIKHJEJ_02822 4.35e-171 - - - L - - - Belongs to the 'phage' integrase family
HEIKHJEJ_02823 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEIKHJEJ_02824 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HEIKHJEJ_02825 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEIKHJEJ_02826 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEIKHJEJ_02827 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HEIKHJEJ_02828 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_02829 2.24e-141 - - - - - - - -
HEIKHJEJ_02830 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEIKHJEJ_02831 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEIKHJEJ_02832 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HEIKHJEJ_02833 1.2e-30 ymzA - - - - - - -
HEIKHJEJ_02834 1.63e-31 - - - - - - - -
HEIKHJEJ_02835 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEIKHJEJ_02836 5.61e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEIKHJEJ_02837 3.13e-75 ymaF - - S - - - YmaF family
HEIKHJEJ_02839 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HEIKHJEJ_02840 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HEIKHJEJ_02841 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HEIKHJEJ_02842 8e-163 ymaC - - S - - - Replication protein
HEIKHJEJ_02844 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HEIKHJEJ_02845 1.04e-204 - - - S - - - Metallo-beta-lactamase superfamily
HEIKHJEJ_02846 8.03e-81 ymzB - - - - - - -
HEIKHJEJ_02847 1.02e-134 pksA - - K - - - Transcriptional regulator
HEIKHJEJ_02848 9.3e-126 ymcC - - S - - - Membrane
HEIKHJEJ_02849 2.23e-90 - - - S - - - Regulatory protein YrvL
HEIKHJEJ_02851 3.06e-204 yuxN - - K - - - Transcriptional regulator
HEIKHJEJ_02852 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_02853 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_02854 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEIKHJEJ_02855 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HEIKHJEJ_02856 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_02857 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEIKHJEJ_02858 1.26e-18 - - - - - - - -
HEIKHJEJ_02860 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
HEIKHJEJ_02862 2.94e-17 - - - EGP - - - Major Facilitator
HEIKHJEJ_02863 6.4e-09 - - - J - - - O-methyltransferase
HEIKHJEJ_02864 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
HEIKHJEJ_02865 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEIKHJEJ_02867 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HEIKHJEJ_02868 3.48e-88 - - - S - - - YusW-like protein
HEIKHJEJ_02869 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEIKHJEJ_02870 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HEIKHJEJ_02871 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HEIKHJEJ_02872 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_02873 4.86e-84 yusQ - - S - - - Tautomerase enzyme
HEIKHJEJ_02874 0.0 yusP - - P - - - Major facilitator superfamily
HEIKHJEJ_02875 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HEIKHJEJ_02876 8.66e-70 yusN - - M - - - Coat F domain
HEIKHJEJ_02877 2.23e-54 - - - - - - - -
HEIKHJEJ_02878 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HEIKHJEJ_02879 1.11e-13 - - - S - - - YuzL-like protein
HEIKHJEJ_02880 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HEIKHJEJ_02881 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HEIKHJEJ_02882 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HEIKHJEJ_02883 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HEIKHJEJ_02884 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEIKHJEJ_02885 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
HEIKHJEJ_02886 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HEIKHJEJ_02887 8.14e-73 yusE - - CO - - - Thioredoxin
HEIKHJEJ_02888 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HEIKHJEJ_02889 1.76e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEIKHJEJ_02890 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HEIKHJEJ_02891 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HEIKHJEJ_02892 6.44e-62 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEIKHJEJ_02893 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEIKHJEJ_02894 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HEIKHJEJ_02895 1.63e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEIKHJEJ_02896 1.79e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HEIKHJEJ_02897 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HEIKHJEJ_02898 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEIKHJEJ_02899 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_02900 3.35e-56 - - - - - - - -
HEIKHJEJ_02902 3.9e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HEIKHJEJ_02903 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HEIKHJEJ_02904 3.71e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEIKHJEJ_02905 1e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HEIKHJEJ_02906 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEIKHJEJ_02907 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HEIKHJEJ_02908 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HEIKHJEJ_02909 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HEIKHJEJ_02910 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HEIKHJEJ_02911 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEIKHJEJ_02912 7.63e-217 bsn - - L - - - Ribonuclease
HEIKHJEJ_02913 6.85e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEIKHJEJ_02914 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEIKHJEJ_02915 5.27e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEIKHJEJ_02916 8.43e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HEIKHJEJ_02917 6.07e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEIKHJEJ_02918 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEIKHJEJ_02919 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEIKHJEJ_02920 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HEIKHJEJ_02921 8.84e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HEIKHJEJ_02922 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HEIKHJEJ_02923 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HEIKHJEJ_02924 1.7e-297 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HEIKHJEJ_02925 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HEIKHJEJ_02926 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEIKHJEJ_02927 3.06e-79 yunG - - - - - - -
HEIKHJEJ_02928 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HEIKHJEJ_02929 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HEIKHJEJ_02930 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEIKHJEJ_02931 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
HEIKHJEJ_02932 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HEIKHJEJ_02933 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HEIKHJEJ_02934 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEIKHJEJ_02935 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEIKHJEJ_02936 3.2e-63 yutD - - S - - - protein conserved in bacteria
HEIKHJEJ_02937 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
HEIKHJEJ_02938 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEIKHJEJ_02939 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HEIKHJEJ_02940 1.55e-253 yutH - - S - - - Spore coat protein
HEIKHJEJ_02941 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HEIKHJEJ_02942 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEIKHJEJ_02943 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEIKHJEJ_02944 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HEIKHJEJ_02945 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HEIKHJEJ_02946 5.44e-74 yuzD - - S - - - protein conserved in bacteria
HEIKHJEJ_02947 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEIKHJEJ_02948 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HEIKHJEJ_02949 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEIKHJEJ_02950 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEIKHJEJ_02951 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HEIKHJEJ_02952 7.01e-128 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HEIKHJEJ_02953 3.64e-138 - - - S - - - Helix-turn-helix domain
HEIKHJEJ_02954 1.36e-87 - - - L - - - Integrase
HEIKHJEJ_02955 1.04e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_02958 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HEIKHJEJ_02959 2.17e-38 - - - - - - - -
HEIKHJEJ_02961 1.78e-73 ydfR - - S - - - Protein of unknown function (DUF421)
HEIKHJEJ_02962 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
HEIKHJEJ_02963 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
HEIKHJEJ_02964 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEIKHJEJ_02965 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HEIKHJEJ_02966 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HEIKHJEJ_02967 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HEIKHJEJ_02968 5.76e-70 - - - S - - - DoxX-like family
HEIKHJEJ_02969 8.04e-111 yycN - - K - - - Acetyltransferase
HEIKHJEJ_02970 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HEIKHJEJ_02971 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_02972 5.94e-118 - - - S - - - DinB family
HEIKHJEJ_02973 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_02974 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HEIKHJEJ_02975 6.42e-147 ydgI - - C - - - nitroreductase
HEIKHJEJ_02976 1.9e-89 - - - K - - - Winged helix DNA-binding domain
HEIKHJEJ_02977 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HEIKHJEJ_02978 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HEIKHJEJ_02979 1.24e-156 ydhC - - K - - - FCD
HEIKHJEJ_02980 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
HEIKHJEJ_02981 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEIKHJEJ_02982 4.28e-163 - - - - - - - -
HEIKHJEJ_02983 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HEIKHJEJ_02984 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HEIKHJEJ_02986 3.12e-107 - - - K - - - Acetyltransferase (GNAT) domain
HEIKHJEJ_02987 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEIKHJEJ_02988 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
HEIKHJEJ_02989 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HEIKHJEJ_02990 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_02991 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_02992 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEIKHJEJ_02993 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEIKHJEJ_02994 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEIKHJEJ_02995 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HEIKHJEJ_02996 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HEIKHJEJ_02997 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEIKHJEJ_02998 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEIKHJEJ_02999 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HEIKHJEJ_03000 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
HEIKHJEJ_03003 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
HEIKHJEJ_03004 1.71e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HEIKHJEJ_03005 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HEIKHJEJ_03006 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEIKHJEJ_03007 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_03008 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HEIKHJEJ_03009 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
HEIKHJEJ_03010 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEIKHJEJ_03011 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEIKHJEJ_03012 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEIKHJEJ_03013 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEIKHJEJ_03014 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEIKHJEJ_03015 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEIKHJEJ_03016 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEIKHJEJ_03017 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEIKHJEJ_03018 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEIKHJEJ_03019 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEIKHJEJ_03020 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HEIKHJEJ_03021 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEIKHJEJ_03022 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HEIKHJEJ_03023 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEIKHJEJ_03024 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEIKHJEJ_03025 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HEIKHJEJ_03026 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HEIKHJEJ_03027 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEIKHJEJ_03028 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEIKHJEJ_03029 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEIKHJEJ_03030 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEIKHJEJ_03031 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEIKHJEJ_03032 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEIKHJEJ_03033 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEIKHJEJ_03034 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEIKHJEJ_03035 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEIKHJEJ_03036 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEIKHJEJ_03037 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEIKHJEJ_03038 6.89e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEIKHJEJ_03039 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEIKHJEJ_03040 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEIKHJEJ_03041 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEIKHJEJ_03042 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEIKHJEJ_03043 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEIKHJEJ_03044 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEIKHJEJ_03045 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEIKHJEJ_03046 7.13e-228 ybaC - - S - - - Alpha/beta hydrolase family
HEIKHJEJ_03047 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEIKHJEJ_03048 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEIKHJEJ_03049 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEIKHJEJ_03050 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEIKHJEJ_03051 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HEIKHJEJ_03052 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEIKHJEJ_03053 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEIKHJEJ_03054 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HEIKHJEJ_03055 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEIKHJEJ_03056 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEIKHJEJ_03057 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEIKHJEJ_03058 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEIKHJEJ_03059 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEIKHJEJ_03060 1.08e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEIKHJEJ_03061 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HEIKHJEJ_03062 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HEIKHJEJ_03063 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEIKHJEJ_03064 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEIKHJEJ_03065 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEIKHJEJ_03066 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HEIKHJEJ_03067 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEIKHJEJ_03068 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEIKHJEJ_03069 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEIKHJEJ_03070 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HEIKHJEJ_03071 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEIKHJEJ_03072 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEIKHJEJ_03073 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HEIKHJEJ_03074 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEIKHJEJ_03075 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HEIKHJEJ_03076 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HEIKHJEJ_03077 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HEIKHJEJ_03078 2.15e-63 ytpI - - S - - - YtpI-like protein
HEIKHJEJ_03079 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HEIKHJEJ_03080 1.15e-39 - - - - - - - -
HEIKHJEJ_03081 5.12e-112 ytrI - - - - - - -
HEIKHJEJ_03082 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HEIKHJEJ_03083 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEIKHJEJ_03084 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HEIKHJEJ_03085 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEIKHJEJ_03086 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEIKHJEJ_03087 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEIKHJEJ_03088 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HEIKHJEJ_03089 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEIKHJEJ_03090 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
HEIKHJEJ_03091 4.46e-93 ytwI - - S - - - membrane
HEIKHJEJ_03092 3.34e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEIKHJEJ_03093 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HEIKHJEJ_03094 4.23e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HEIKHJEJ_03095 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_03096 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HEIKHJEJ_03097 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEIKHJEJ_03098 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEIKHJEJ_03099 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HEIKHJEJ_03100 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEIKHJEJ_03101 4.54e-205 ytbE - - S - - - reductase
HEIKHJEJ_03102 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HEIKHJEJ_03103 1.64e-86 ytcD - - K - - - Transcriptional regulator
HEIKHJEJ_03104 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEIKHJEJ_03105 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEIKHJEJ_03106 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEIKHJEJ_03107 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HEIKHJEJ_03108 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HEIKHJEJ_03109 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HEIKHJEJ_03110 5.5e-202 ytxC - - S - - - YtxC-like family
HEIKHJEJ_03112 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEIKHJEJ_03113 1.15e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HEIKHJEJ_03114 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_03115 4.62e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HEIKHJEJ_03116 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEIKHJEJ_03117 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEIKHJEJ_03119 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEIKHJEJ_03120 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEIKHJEJ_03121 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEIKHJEJ_03122 3.65e-59 ysdA - - S - - - Membrane
HEIKHJEJ_03123 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HEIKHJEJ_03124 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
HEIKHJEJ_03125 4.74e-72 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HEIKHJEJ_03126 5.69e-126 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HEIKHJEJ_03127 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HEIKHJEJ_03128 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HEIKHJEJ_03129 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEIKHJEJ_03130 5.81e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HEIKHJEJ_03131 1.24e-280 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEIKHJEJ_03132 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HEIKHJEJ_03133 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HEIKHJEJ_03134 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HEIKHJEJ_03135 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HEIKHJEJ_03136 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HEIKHJEJ_03138 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
HEIKHJEJ_03139 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HEIKHJEJ_03140 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HEIKHJEJ_03141 1.11e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HEIKHJEJ_03142 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HEIKHJEJ_03143 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEIKHJEJ_03144 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEIKHJEJ_03145 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEIKHJEJ_03146 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEIKHJEJ_03147 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEIKHJEJ_03148 3.12e-111 yshB - - S - - - membrane protein, required for colicin V production
HEIKHJEJ_03149 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HEIKHJEJ_03150 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEIKHJEJ_03151 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HEIKHJEJ_03152 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEIKHJEJ_03153 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03154 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HEIKHJEJ_03155 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HEIKHJEJ_03156 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HEIKHJEJ_03158 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HEIKHJEJ_03159 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEIKHJEJ_03160 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEIKHJEJ_03161 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEIKHJEJ_03162 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HEIKHJEJ_03163 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HEIKHJEJ_03164 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HEIKHJEJ_03165 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HEIKHJEJ_03166 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HEIKHJEJ_03167 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03168 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_03169 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEIKHJEJ_03170 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HEIKHJEJ_03171 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEIKHJEJ_03172 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEIKHJEJ_03173 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HEIKHJEJ_03175 3.17e-170 - - - L - - - Phage integrase family
HEIKHJEJ_03178 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HEIKHJEJ_03179 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
HEIKHJEJ_03180 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HEIKHJEJ_03181 3.84e-87 res - - L - - - Resolvase, N terminal domain
HEIKHJEJ_03183 1.14e-124 - - - L - - - Integrase
HEIKHJEJ_03184 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HEIKHJEJ_03185 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HEIKHJEJ_03186 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03187 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEIKHJEJ_03188 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEIKHJEJ_03189 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HEIKHJEJ_03190 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03191 5.87e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEIKHJEJ_03192 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEIKHJEJ_03193 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEIKHJEJ_03194 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEIKHJEJ_03195 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_03196 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HEIKHJEJ_03197 7.05e-172 yoxB - - - - - - -
HEIKHJEJ_03198 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEIKHJEJ_03199 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_03200 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_03201 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEIKHJEJ_03202 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_03203 1.24e-299 yoaB - - EGP - - - the major facilitator superfamily
HEIKHJEJ_03209 4.34e-30 - - - K - - - Sigma-70, region 4
HEIKHJEJ_03212 2.14e-51 - - - - - - - -
HEIKHJEJ_03215 3.04e-11 - - - - - - - -
HEIKHJEJ_03216 1.12e-86 - - - L - - - Phage integrase family
HEIKHJEJ_03217 5.35e-169 - - - S - - - TIGRFAM Phage uncharacterised protein, C-terminal
HEIKHJEJ_03218 7.57e-31 - - - S - - - Helix-turn-helix of insertion element transposase
HEIKHJEJ_03219 1.27e-192 - - - - - - - -
HEIKHJEJ_03220 2.45e-106 - - - S - - - Phage minor capsid protein 2
HEIKHJEJ_03221 4.51e-08 - - - S - - - Domain of unknown function (DUF4355)
HEIKHJEJ_03222 1.74e-102 - - - - - - - -
HEIKHJEJ_03224 2.82e-34 - - - - - - - -
HEIKHJEJ_03225 4.04e-22 - - - - - - - -
HEIKHJEJ_03226 7.61e-40 - - - - - - - -
HEIKHJEJ_03227 1.56e-65 - - - N - - - domain, Protein
HEIKHJEJ_03228 7.39e-33 - - - - - - - -
HEIKHJEJ_03230 9.06e-135 - - - D - - - phage tail tape measure protein
HEIKHJEJ_03231 1.37e-67 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HEIKHJEJ_03232 7.54e-92 - - - L - - - Prophage endopeptidase tail
HEIKHJEJ_03233 1.94e-180 yddG - - S - - - maturation of SSU-rRNA
HEIKHJEJ_03234 1.03e-237 yddH - - M - - - Lysozyme-like
HEIKHJEJ_03235 3.19e-111 yddI - - - - - - -
HEIKHJEJ_03236 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
HEIKHJEJ_03237 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
HEIKHJEJ_03238 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_03240 9.39e-63 yhcM - - - - - - -
HEIKHJEJ_03241 6e-104 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEIKHJEJ_03242 1.01e-217 yhcP - - - - - - -
HEIKHJEJ_03243 8.34e-128 yhcQ - - M - - - Spore coat protein
HEIKHJEJ_03244 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEIKHJEJ_03245 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HEIKHJEJ_03246 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEIKHJEJ_03247 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
HEIKHJEJ_03248 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
HEIKHJEJ_03249 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
HEIKHJEJ_03250 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEIKHJEJ_03251 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEIKHJEJ_03252 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEIKHJEJ_03253 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HEIKHJEJ_03254 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEIKHJEJ_03255 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEIKHJEJ_03256 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HEIKHJEJ_03257 1.27e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_03258 1.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_03259 2.7e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HEIKHJEJ_03260 1.65e-51 yhdB - - S - - - YhdB-like protein
HEIKHJEJ_03261 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
HEIKHJEJ_03262 4.06e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEIKHJEJ_03263 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HEIKHJEJ_03264 1.51e-306 ygxB - - M - - - Conserved TM helix
HEIKHJEJ_03265 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HEIKHJEJ_03266 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HEIKHJEJ_03267 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HEIKHJEJ_03268 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03269 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEIKHJEJ_03270 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_03271 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
HEIKHJEJ_03272 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEIKHJEJ_03273 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_03274 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_03275 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HEIKHJEJ_03276 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
HEIKHJEJ_03277 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_03278 2.74e-243 yhdN - - C - - - Aldo keto reductase
HEIKHJEJ_03279 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEIKHJEJ_03280 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HEIKHJEJ_03281 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HEIKHJEJ_03282 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEIKHJEJ_03283 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HEIKHJEJ_03284 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HEIKHJEJ_03285 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEIKHJEJ_03286 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEIKHJEJ_03287 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEIKHJEJ_03288 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HEIKHJEJ_03289 3.04e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HEIKHJEJ_03290 8.05e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEIKHJEJ_03291 5.03e-194 nodB1 - - G - - - deacetylase
HEIKHJEJ_03292 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEIKHJEJ_03293 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HEIKHJEJ_03294 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
HEIKHJEJ_03295 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_03296 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_03297 1.29e-140 yheG - - GM - - - NAD(P)H-binding
HEIKHJEJ_03298 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HEIKHJEJ_03299 5.64e-32 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HEIKHJEJ_03300 9.06e-65 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HEIKHJEJ_03301 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEIKHJEJ_03302 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
HEIKHJEJ_03303 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEIKHJEJ_03304 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEIKHJEJ_03305 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEIKHJEJ_03306 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEIKHJEJ_03307 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HEIKHJEJ_03308 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HEIKHJEJ_03310 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEIKHJEJ_03311 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HEIKHJEJ_03312 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HEIKHJEJ_03313 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEIKHJEJ_03314 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HEIKHJEJ_03315 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEIKHJEJ_03316 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HEIKHJEJ_03317 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HEIKHJEJ_03318 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HEIKHJEJ_03319 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEIKHJEJ_03320 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HEIKHJEJ_03321 3.42e-157 yflK - - S - - - protein conserved in bacteria
HEIKHJEJ_03322 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HEIKHJEJ_03323 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
HEIKHJEJ_03324 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HEIKHJEJ_03325 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEIKHJEJ_03326 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEIKHJEJ_03327 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HEIKHJEJ_03328 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HEIKHJEJ_03329 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HEIKHJEJ_03330 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_03331 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEIKHJEJ_03332 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HEIKHJEJ_03333 6.16e-160 frp - - C - - - nitroreductase
HEIKHJEJ_03334 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HEIKHJEJ_03335 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
HEIKHJEJ_03336 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HEIKHJEJ_03337 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HEIKHJEJ_03338 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_03339 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_03340 4.79e-160 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03341 1.98e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_03342 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEIKHJEJ_03343 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HEIKHJEJ_03344 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HEIKHJEJ_03345 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEIKHJEJ_03346 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HEIKHJEJ_03347 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEIKHJEJ_03348 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HEIKHJEJ_03349 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HEIKHJEJ_03350 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HEIKHJEJ_03351 2.19e-153 yxaC - - M - - - effector of murein hydrolase
HEIKHJEJ_03352 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HEIKHJEJ_03353 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEIKHJEJ_03354 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_03355 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HEIKHJEJ_03356 7.7e-248 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HEIKHJEJ_03358 1.49e-207 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
HEIKHJEJ_03359 4.82e-294 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEIKHJEJ_03361 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HEIKHJEJ_03362 0.0 lytB - - D - - - Stage II sporulation protein
HEIKHJEJ_03363 1.39e-15 - - - - - - - -
HEIKHJEJ_03364 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEIKHJEJ_03365 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HEIKHJEJ_03366 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HEIKHJEJ_03367 2.75e-136 ytqB - - J - - - Putative rRNA methylase
HEIKHJEJ_03368 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HEIKHJEJ_03369 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HEIKHJEJ_03370 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEIKHJEJ_03371 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_03372 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEIKHJEJ_03373 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEIKHJEJ_03374 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEIKHJEJ_03375 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HEIKHJEJ_03376 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEIKHJEJ_03377 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEIKHJEJ_03378 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEIKHJEJ_03379 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEIKHJEJ_03380 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HEIKHJEJ_03381 1.59e-81 ytkC - - S - - - Bacteriophage holin family
HEIKHJEJ_03382 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HEIKHJEJ_03384 6.79e-95 ytkA - - S - - - YtkA-like
HEIKHJEJ_03385 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEIKHJEJ_03386 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HEIKHJEJ_03387 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HEIKHJEJ_03388 3e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HEIKHJEJ_03389 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEIKHJEJ_03390 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HEIKHJEJ_03391 7.59e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HEIKHJEJ_03392 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEIKHJEJ_03393 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEIKHJEJ_03394 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEIKHJEJ_03395 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEIKHJEJ_03396 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEIKHJEJ_03397 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEIKHJEJ_03398 4.49e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEIKHJEJ_03399 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEIKHJEJ_03400 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HEIKHJEJ_03401 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
HEIKHJEJ_03402 2.32e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HEIKHJEJ_03403 6.8e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEIKHJEJ_03404 7.97e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
HEIKHJEJ_03405 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HEIKHJEJ_03407 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HEIKHJEJ_03408 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HEIKHJEJ_03409 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
HEIKHJEJ_03410 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HEIKHJEJ_03411 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEIKHJEJ_03412 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEIKHJEJ_03413 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HEIKHJEJ_03414 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEIKHJEJ_03415 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEIKHJEJ_03437 2.17e-224 - - - L - - - Replication protein
HEIKHJEJ_03439 1.81e-108 - - - K - - - Transcriptional regulator
HEIKHJEJ_03440 5.09e-304 pre - - D - - - plasmid recombination enzyme
HEIKHJEJ_03441 9.66e-92 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
HEIKHJEJ_03442 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
HEIKHJEJ_03443 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HEIKHJEJ_03444 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HEIKHJEJ_03445 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HEIKHJEJ_03446 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HEIKHJEJ_03447 5.44e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HEIKHJEJ_03448 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
HEIKHJEJ_03449 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HEIKHJEJ_03450 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_03451 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEIKHJEJ_03452 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HEIKHJEJ_03453 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEIKHJEJ_03454 5.14e-161 yfmS - - NT - - - chemotaxis protein
HEIKHJEJ_03455 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEIKHJEJ_03456 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HEIKHJEJ_03457 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HEIKHJEJ_03458 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HEIKHJEJ_03459 5.3e-47 - - - - - - - -
HEIKHJEJ_03460 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HEIKHJEJ_03461 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEIKHJEJ_03462 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEIKHJEJ_03463 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEIKHJEJ_03465 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HEIKHJEJ_03466 6.27e-67 yerC - - S - - - protein conserved in bacteria
HEIKHJEJ_03467 1.25e-239 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HEIKHJEJ_03468 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HEIKHJEJ_03469 1.87e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HEIKHJEJ_03470 1.11e-95 - - - K - - - helix_turn_helix ASNC type
HEIKHJEJ_03471 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HEIKHJEJ_03472 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HEIKHJEJ_03473 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEIKHJEJ_03474 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HEIKHJEJ_03475 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEIKHJEJ_03476 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEIKHJEJ_03477 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEIKHJEJ_03478 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEIKHJEJ_03479 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HEIKHJEJ_03480 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEIKHJEJ_03481 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEIKHJEJ_03482 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEIKHJEJ_03483 3.13e-38 yebG - - S - - - NETI protein
HEIKHJEJ_03484 2.66e-120 yebE - - S - - - UPF0316 protein
HEIKHJEJ_03486 5.85e-165 yebC - - M - - - Membrane
HEIKHJEJ_03487 1.33e-280 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HEIKHJEJ_03489 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEIKHJEJ_03490 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HEIKHJEJ_03491 2.63e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEIKHJEJ_03492 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HEIKHJEJ_03493 4.82e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEIKHJEJ_03494 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_03495 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HEIKHJEJ_03496 8.17e-25 yeaA - - S - - - Protein of unknown function (DUF4003)
HEIKHJEJ_03497 1.08e-188 yeaA - - S - - - Protein of unknown function (DUF4003)
HEIKHJEJ_03498 1.46e-201 - - - I - - - Alpha/beta hydrolase family
HEIKHJEJ_03499 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
HEIKHJEJ_03501 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEIKHJEJ_03502 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HEIKHJEJ_03503 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEIKHJEJ_03504 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HEIKHJEJ_03505 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HEIKHJEJ_03506 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEIKHJEJ_03507 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEIKHJEJ_03508 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
HEIKHJEJ_03509 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
HEIKHJEJ_03510 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HEIKHJEJ_03511 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HEIKHJEJ_03512 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HEIKHJEJ_03513 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HEIKHJEJ_03514 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEIKHJEJ_03515 1.92e-08 - - - - - - - -
HEIKHJEJ_03516 7.41e-37 - - - S - - - Protein of unknown function (DUF3813)
HEIKHJEJ_03517 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HEIKHJEJ_03518 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEIKHJEJ_03519 4.16e-198 yitS - - S - - - protein conserved in bacteria
HEIKHJEJ_03520 7.32e-49 yitR - - S - - - Domain of unknown function (DUF3784)
HEIKHJEJ_03521 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HEIKHJEJ_03522 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_03523 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HEIKHJEJ_03524 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_03525 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEIKHJEJ_03526 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_03527 1.22e-81 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEIKHJEJ_03528 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEIKHJEJ_03529 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEIKHJEJ_03530 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_03531 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEIKHJEJ_03532 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HEIKHJEJ_03533 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HEIKHJEJ_03534 1.05e-26 yxzF - - - - - - -
HEIKHJEJ_03535 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HEIKHJEJ_03536 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HEIKHJEJ_03537 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
HEIKHJEJ_03538 1.55e-176 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEIKHJEJ_03539 2.01e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_03540 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HEIKHJEJ_03541 1.63e-39 - - - - - - - -
HEIKHJEJ_03542 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
HEIKHJEJ_03543 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEIKHJEJ_03544 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HEIKHJEJ_03545 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEIKHJEJ_03546 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HEIKHJEJ_03547 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HEIKHJEJ_03548 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HEIKHJEJ_03549 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HEIKHJEJ_03550 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
HEIKHJEJ_03551 0.0 - - - O - - - Peptidase family M48
HEIKHJEJ_03553 8.67e-195 yxkH - - G - - - Polysaccharide deacetylase
HEIKHJEJ_03555 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEIKHJEJ_03556 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03557 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HEIKHJEJ_03558 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEIKHJEJ_03559 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HEIKHJEJ_03560 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEIKHJEJ_03561 1.38e-105 yrrD - - S - - - protein conserved in bacteria
HEIKHJEJ_03562 8.4e-42 yrzR - - - - - - -
HEIKHJEJ_03563 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HEIKHJEJ_03564 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_03565 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEIKHJEJ_03566 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEIKHJEJ_03567 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEIKHJEJ_03568 1.25e-241 yrrI - - S - - - AI-2E family transporter
HEIKHJEJ_03569 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEIKHJEJ_03570 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HEIKHJEJ_03571 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEIKHJEJ_03572 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HEIKHJEJ_03573 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEIKHJEJ_03574 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HEIKHJEJ_03575 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HEIKHJEJ_03576 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HEIKHJEJ_03577 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HEIKHJEJ_03578 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEIKHJEJ_03579 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HEIKHJEJ_03580 1.65e-101 yrrS - - S - - - Protein of unknown function (DUF1510)
HEIKHJEJ_03581 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HEIKHJEJ_03582 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEIKHJEJ_03583 1.14e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEIKHJEJ_03584 3.91e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HEIKHJEJ_03585 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEIKHJEJ_03586 5.71e-48 yrhC - - S - - - YrhC-like protein
HEIKHJEJ_03587 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HEIKHJEJ_03588 5.46e-74 ygzB - - S - - - UPF0295 protein
HEIKHJEJ_03589 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEIKHJEJ_03590 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HEIKHJEJ_03591 1.89e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HEIKHJEJ_03592 1.08e-237 ygaE - - S - - - Membrane
HEIKHJEJ_03593 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HEIKHJEJ_03594 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HEIKHJEJ_03595 2.01e-49 ygaB - - S - - - YgaB-like protein
HEIKHJEJ_03596 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HEIKHJEJ_03597 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_03598 1.73e-48 yfhS - - - - - - -
HEIKHJEJ_03599 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HEIKHJEJ_03600 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HEIKHJEJ_03601 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEIKHJEJ_03602 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HEIKHJEJ_03603 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HEIKHJEJ_03604 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
HEIKHJEJ_03605 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
HEIKHJEJ_03606 8.95e-60 yfhJ - - S - - - WVELL protein
HEIKHJEJ_03607 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HEIKHJEJ_03608 2.45e-268 yfhI - - EGP - - - -transporter
HEIKHJEJ_03610 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
HEIKHJEJ_03611 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HEIKHJEJ_03612 1.88e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HEIKHJEJ_03614 3.61e-34 yfhD - - S - - - YfhD-like protein
HEIKHJEJ_03615 4.76e-137 yfhC - - C - - - nitroreductase
HEIKHJEJ_03616 3.1e-214 yfhB - - S - - - PhzF family
HEIKHJEJ_03617 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_03618 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEIKHJEJ_03619 3.15e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HEIKHJEJ_03620 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEIKHJEJ_03621 2.11e-103 yfiV - - K - - - transcriptional
HEIKHJEJ_03622 7.36e-215 yfiU - - EGP - - - the major facilitator superfamily
HEIKHJEJ_03623 1.74e-131 yfiU - - EGP - - - the major facilitator superfamily
HEIKHJEJ_03624 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HEIKHJEJ_03625 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
HEIKHJEJ_03626 1.57e-136 yfiR - - K - - - Transcriptional regulator
HEIKHJEJ_03627 6.57e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEIKHJEJ_03628 5.67e-121 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEIKHJEJ_03629 1.38e-121 padR - - K - - - transcriptional
HEIKHJEJ_03630 6.08e-256 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HEIKHJEJ_03631 1.34e-260 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEIKHJEJ_03632 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_03633 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HEIKHJEJ_03634 1.7e-272 baeS - - T - - - Histidine kinase
HEIKHJEJ_03636 4.36e-249 - - - S - - - Oxidoreductase
HEIKHJEJ_03637 2.46e-32 - - - S - - - Oxidoreductase
HEIKHJEJ_03638 5.47e-234 - - - G - - - Xylose isomerase
HEIKHJEJ_03639 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_03640 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
HEIKHJEJ_03641 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HEIKHJEJ_03642 4.74e-83 yfiD3 - - S - - - DoxX
HEIKHJEJ_03643 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HEIKHJEJ_03644 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEIKHJEJ_03645 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
HEIKHJEJ_03646 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_03647 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HEIKHJEJ_03648 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEIKHJEJ_03649 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HEIKHJEJ_03650 9.8e-313 yoeA - - V - - - MATE efflux family protein
HEIKHJEJ_03651 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HEIKHJEJ_03652 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HEIKHJEJ_03653 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEIKHJEJ_03654 8.82e-37 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HEIKHJEJ_03655 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HEIKHJEJ_03656 8.25e-199 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HEIKHJEJ_03657 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
HEIKHJEJ_03658 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HEIKHJEJ_03659 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HEIKHJEJ_03660 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEIKHJEJ_03661 2.81e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HEIKHJEJ_03662 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HEIKHJEJ_03663 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HEIKHJEJ_03664 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HEIKHJEJ_03665 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEIKHJEJ_03666 1.23e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HEIKHJEJ_03667 2.01e-134 yngC - - S - - - membrane-associated protein
HEIKHJEJ_03668 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEIKHJEJ_03669 1.72e-103 yngA - - S - - - membrane
HEIKHJEJ_03670 5.64e-35 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HEIKHJEJ_03671 3.29e-308 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HEIKHJEJ_03672 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HEIKHJEJ_03674 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HEIKHJEJ_03675 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HEIKHJEJ_03676 8.74e-75 ynfC - - - - - - -
HEIKHJEJ_03677 1.82e-18 - - - - - - - -
HEIKHJEJ_03678 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEIKHJEJ_03679 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEIKHJEJ_03680 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HEIKHJEJ_03681 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEIKHJEJ_03682 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HEIKHJEJ_03683 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HEIKHJEJ_03684 3.26e-72 - - - L - - - transposase activity
HEIKHJEJ_03686 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEIKHJEJ_03687 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEIKHJEJ_03688 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
HEIKHJEJ_03689 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEIKHJEJ_03690 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HEIKHJEJ_03692 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEIKHJEJ_03693 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEIKHJEJ_03694 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HEIKHJEJ_03695 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEIKHJEJ_03696 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEIKHJEJ_03697 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEIKHJEJ_03698 3.57e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEIKHJEJ_03699 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEIKHJEJ_03700 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HEIKHJEJ_03701 1.05e-255 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HEIKHJEJ_03702 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_03703 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
HEIKHJEJ_03704 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HEIKHJEJ_03705 9.23e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEIKHJEJ_03706 2.29e-29 ywtC - - - - - - -
HEIKHJEJ_03707 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEIKHJEJ_03708 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HEIKHJEJ_03709 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEIKHJEJ_03710 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HEIKHJEJ_03711 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEIKHJEJ_03712 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEIKHJEJ_03713 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEIKHJEJ_03714 1.59e-201 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEIKHJEJ_03715 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HEIKHJEJ_03716 3.97e-119 batE - - T - - - Sh3 type 3 domain protein
HEIKHJEJ_03722 3.88e-34 - - - - - - - -
HEIKHJEJ_03723 4.26e-66 - - - - - - - -
HEIKHJEJ_03724 4.6e-99 - - - - - - - -
HEIKHJEJ_03725 1.43e-138 - - - NU ko:K02283 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
HEIKHJEJ_03729 1.64e-278 - - - M - - - domain protein
HEIKHJEJ_03732 2.47e-36 - - - S - - - Domain of unknown function (DUF5052)
HEIKHJEJ_03736 0.000863 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_03738 6.01e-61 - - - K - - - COG0457 FOG TPR repeat
HEIKHJEJ_03739 1.4e-193 - - - - ko:K18640 - ko00000,ko04812 -
HEIKHJEJ_03744 8.02e-30 - - - V - - - VanZ like family
HEIKHJEJ_03746 3.15e-36 - - - - - - - -
HEIKHJEJ_03747 4.3e-201 - - - S - - - damaged DNA binding
HEIKHJEJ_03761 8.73e-109 - - - L - - - Domain of unknown function (DUF1738)
HEIKHJEJ_03764 3.45e-48 nucH 3.1.31.1 - L ko:K01174 - ko00000,ko01000 COG1525 Micrococcal nuclease (thermonuclease) homologs
HEIKHJEJ_03767 1.32e-151 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
HEIKHJEJ_03773 2.28e-53 - - - L - - - Site-specific recombinase, phage integrase family
HEIKHJEJ_03776 4.64e-65 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEIKHJEJ_03778 2.5e-06 rok - - S - - - Repressor of ComK
HEIKHJEJ_03782 2.51e-49 - - - L - - - Protein of unknown function (DUF3991)
HEIKHJEJ_03784 1.86e-111 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
HEIKHJEJ_03788 9.35e-69 yddH - - M - - - Lysozyme-like
HEIKHJEJ_03790 5.71e-216 - - - S - - - AAA-like domain
HEIKHJEJ_03791 1.47e-47 - - - - - - - -
HEIKHJEJ_03793 4.33e-50 - - - S - - - domain, Protein
HEIKHJEJ_03794 4.48e-214 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
HEIKHJEJ_03797 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HEIKHJEJ_03798 2.1e-71 ydfQ - - CO - - - Thioredoxin
HEIKHJEJ_03799 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HEIKHJEJ_03800 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEIKHJEJ_03801 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HEIKHJEJ_03802 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEIKHJEJ_03803 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
HEIKHJEJ_03804 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HEIKHJEJ_03805 2.2e-222 - - - S - - - Alpha/beta hydrolase family
HEIKHJEJ_03806 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HEIKHJEJ_03807 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEIKHJEJ_03808 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_03810 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEIKHJEJ_03811 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEIKHJEJ_03812 4.04e-149 ydfE - - S - - - Flavin reductase like domain
HEIKHJEJ_03813 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HEIKHJEJ_03814 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_03815 9.99e-197 - - - EG - - - EamA-like transporter family
HEIKHJEJ_03816 8.66e-186 - - - J - - - GNAT acetyltransferase
HEIKHJEJ_03817 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEIKHJEJ_03818 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HEIKHJEJ_03819 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEIKHJEJ_03820 4.66e-16 - - - K - - - HxlR-like helix-turn-helix
HEIKHJEJ_03821 2.7e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
HEIKHJEJ_03822 8.69e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HEIKHJEJ_03823 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEIKHJEJ_03824 9.01e-195 ydeK - - EG - - - -transporter
HEIKHJEJ_03825 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
HEIKHJEJ_03826 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HEIKHJEJ_03827 2.51e-36 - - - S - - - SNARE associated Golgi protein
HEIKHJEJ_03828 3.64e-142 - - - - - - - -
HEIKHJEJ_03829 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HEIKHJEJ_03830 0.0 - - - - - - - -
HEIKHJEJ_03831 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HEIKHJEJ_03832 1.96e-141 - - - S - - - Phage tail protein
HEIKHJEJ_03833 0.0 - - - S - - - peptidoglycan catabolic process
HEIKHJEJ_03834 4.09e-16 - - - - - - - -
HEIKHJEJ_03835 1.58e-36 - - - - - - - -
HEIKHJEJ_03836 9.75e-79 - - - - - - - -
HEIKHJEJ_03837 1.42e-40 - - - - - - - -
HEIKHJEJ_03838 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HEIKHJEJ_03839 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
HEIKHJEJ_03840 1.23e-39 - - - S - - - peptidoglycan catabolic process
HEIKHJEJ_03841 8.02e-09 - - - S - - - peptidoglycan catabolic process
HEIKHJEJ_03842 3.43e-227 - - - S - - - capsid protein
HEIKHJEJ_03843 9.36e-135 - - - S - - - peptidase activity
HEIKHJEJ_03844 4.77e-273 - - - S - - - Phage portal protein
HEIKHJEJ_03845 2.58e-14 - - - - - - - -
HEIKHJEJ_03846 1.37e-277 - - - S - - - Phage Terminase
HEIKHJEJ_03847 1e-89 - - - S - - - Phage terminase, small subunit
HEIKHJEJ_03848 2.63e-11 - - - - - - - -
HEIKHJEJ_03849 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HEIKHJEJ_03850 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HEIKHJEJ_03851 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_03852 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
HEIKHJEJ_03853 2.25e-59 ybfN - - - - - - -
HEIKHJEJ_03854 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEIKHJEJ_03855 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HEIKHJEJ_03856 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEIKHJEJ_03857 1.31e-212 - - - S - - - Alpha/beta hydrolase family
HEIKHJEJ_03859 1.69e-228 mpr - - M - - - Belongs to the peptidase S1B family
HEIKHJEJ_03860 4.6e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEIKHJEJ_03861 2.61e-73 - - - - - - - -
HEIKHJEJ_03862 1.96e-111 - - GH19 M ko:K03791 - ko00000 Lysin motif
HEIKHJEJ_03865 5.37e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_03867 1.92e-145 - - - S - - - Helix-turn-helix domain
HEIKHJEJ_03868 6.09e-40 - - - L - - - Phage integrase family
HEIKHJEJ_03870 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEIKHJEJ_03871 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HEIKHJEJ_03872 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HEIKHJEJ_03873 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HEIKHJEJ_03874 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
HEIKHJEJ_03875 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HEIKHJEJ_03876 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HEIKHJEJ_03877 2.83e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HEIKHJEJ_03878 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HEIKHJEJ_03879 6.55e-223 yvdE - - K - - - Transcriptional regulator
HEIKHJEJ_03880 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEIKHJEJ_03881 1.27e-39 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HEIKHJEJ_03882 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HEIKHJEJ_03883 1.07e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HEIKHJEJ_03884 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEIKHJEJ_03885 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HEIKHJEJ_03886 1.05e-179 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEIKHJEJ_03887 1.38e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HEIKHJEJ_03888 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEIKHJEJ_03889 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HEIKHJEJ_03890 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HEIKHJEJ_03891 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEIKHJEJ_03892 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HEIKHJEJ_03893 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEIKHJEJ_03894 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEIKHJEJ_03895 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEIKHJEJ_03896 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HEIKHJEJ_03897 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HEIKHJEJ_03898 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HEIKHJEJ_03900 0.0 - - - - - - - -
HEIKHJEJ_03901 1.29e-111 - - - - - - - -
HEIKHJEJ_03902 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HEIKHJEJ_03903 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEIKHJEJ_03904 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEIKHJEJ_03905 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEIKHJEJ_03906 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HEIKHJEJ_03907 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEIKHJEJ_03908 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEIKHJEJ_03909 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEIKHJEJ_03910 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
HEIKHJEJ_03911 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HEIKHJEJ_03912 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HEIKHJEJ_03913 1.79e-84 ydjM - - M - - - Lytic transglycolase
HEIKHJEJ_03914 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HEIKHJEJ_03915 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_03916 1.53e-245 - - - S - - - Ion transport 2 domain protein
HEIKHJEJ_03917 5.98e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HEIKHJEJ_03918 1.48e-172 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HEIKHJEJ_03919 1.42e-225 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEIKHJEJ_03920 8.87e-76 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HEIKHJEJ_03921 3.64e-59 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HEIKHJEJ_03922 1.22e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HEIKHJEJ_03923 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HEIKHJEJ_03924 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HEIKHJEJ_03925 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HEIKHJEJ_03926 5.53e-175 - - - - - - - -
HEIKHJEJ_03927 1.17e-148 - - - - - - - -
HEIKHJEJ_03929 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEIKHJEJ_03930 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEIKHJEJ_03931 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEIKHJEJ_03932 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HEIKHJEJ_03933 8.36e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEIKHJEJ_03934 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEIKHJEJ_03935 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEIKHJEJ_03936 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEIKHJEJ_03937 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HEIKHJEJ_03939 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEIKHJEJ_03940 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEIKHJEJ_03941 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HEIKHJEJ_03942 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HEIKHJEJ_03943 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEIKHJEJ_03948 7.55e-59 orfX1 - - L - - - Transposase
HEIKHJEJ_03949 5.6e-173 - - - L - - - Integrase core domain
HEIKHJEJ_03950 1.14e-90 - - - S - - - CAAX protease self-immunity
HEIKHJEJ_03951 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEIKHJEJ_03952 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_03953 1.6e-08 - - - S - - - Domain of unknown function (DUF3885)
HEIKHJEJ_03954 1.9e-102 - - - S - - - Domain of unknown function (DUF3885)
HEIKHJEJ_03955 4.19e-20 ynaF - - - - - - -
HEIKHJEJ_03957 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
HEIKHJEJ_03958 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEIKHJEJ_03959 6.88e-84 - - - S - - - HTH-like domain
HEIKHJEJ_03960 0.0 - - - L - - - AAA ATPase domain
HEIKHJEJ_03961 0.0 - - - L - - - Superfamily I DNA and RNA helicases
HEIKHJEJ_03962 0.0 - - - V - - - Abi-like protein
HEIKHJEJ_03963 2.64e-42 - - - - - - - -
HEIKHJEJ_03964 6.72e-171 - - - M - - - Membrane
HEIKHJEJ_03965 1.3e-38 yetM - - CH - - - FAD binding domain
HEIKHJEJ_03966 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEIKHJEJ_03967 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HEIKHJEJ_03968 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEIKHJEJ_03969 3.28e-44 - - - - - - - -
HEIKHJEJ_03970 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEIKHJEJ_03971 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HEIKHJEJ_03972 3.66e-157 yetF - - S - - - membrane
HEIKHJEJ_03973 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEIKHJEJ_03974 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEIKHJEJ_03975 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HEIKHJEJ_03976 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEIKHJEJ_03977 1.54e-213 yetA - - - - - - -
HEIKHJEJ_03978 5.02e-234 yetA - - - - - - -
HEIKHJEJ_03979 2.25e-127 yetA - - - - - - -
HEIKHJEJ_03980 2.97e-193 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HEIKHJEJ_03981 8.37e-153 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HEIKHJEJ_03982 2.73e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HEIKHJEJ_03983 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEIKHJEJ_03984 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HEIKHJEJ_03985 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HEIKHJEJ_03986 2.32e-144 - - - S - - - Protein of unknown function, DUF624
HEIKHJEJ_03987 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
HEIKHJEJ_03988 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEIKHJEJ_03989 0.0 yesS - - K - - - Transcriptional regulator
HEIKHJEJ_03990 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HEIKHJEJ_03991 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEIKHJEJ_03992 1.17e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEIKHJEJ_03993 7.99e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEIKHJEJ_03994 2.41e-199 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HEIKHJEJ_03995 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_03996 6.29e-133 yesL - - S - - - Protein of unknown function, DUF624
HEIKHJEJ_03997 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
HEIKHJEJ_03998 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HEIKHJEJ_03999 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HEIKHJEJ_04000 1.55e-59 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HEIKHJEJ_04001 9.52e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_04003 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HEIKHJEJ_04005 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HEIKHJEJ_04006 1.06e-73 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HEIKHJEJ_04007 1.25e-123 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
HEIKHJEJ_04008 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HEIKHJEJ_04009 1.41e-72 - - - S - - - Protein of unknown function, DUF600
HEIKHJEJ_04011 0.0 - - - K - - - SIR2-like domain
HEIKHJEJ_04012 1.14e-27 - - - - - - - -
HEIKHJEJ_04013 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEIKHJEJ_04014 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEIKHJEJ_04015 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEIKHJEJ_04016 6.97e-189 yerO - - K - - - Transcriptional regulator
HEIKHJEJ_04017 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HEIKHJEJ_04018 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HEIKHJEJ_04019 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HEIKHJEJ_04020 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HEIKHJEJ_04021 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEIKHJEJ_04022 1.54e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEIKHJEJ_04023 1.28e-201 ywbI - - K - - - Transcriptional regulator
HEIKHJEJ_04024 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEIKHJEJ_04025 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HEIKHJEJ_04026 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HEIKHJEJ_04027 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HEIKHJEJ_04028 1.9e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HEIKHJEJ_04029 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HEIKHJEJ_04030 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
HEIKHJEJ_04031 1.05e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEIKHJEJ_04032 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HEIKHJEJ_04033 2.67e-308 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_04034 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HEIKHJEJ_04035 1.54e-215 gspA - - M - - - General stress
HEIKHJEJ_04036 3.49e-158 ywaF - - S - - - Integral membrane protein
HEIKHJEJ_04037 1.25e-114 ywaE - - K - - - Transcriptional regulator
HEIKHJEJ_04038 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEIKHJEJ_04039 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HEIKHJEJ_04040 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HEIKHJEJ_04041 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEIKHJEJ_04042 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HEIKHJEJ_04043 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HEIKHJEJ_04044 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HEIKHJEJ_04045 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HEIKHJEJ_04046 6.01e-99 ykuL - - S - - - CBS domain
HEIKHJEJ_04047 7.61e-215 ccpC - - K - - - Transcriptional regulator
HEIKHJEJ_04048 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
HEIKHJEJ_04049 1.74e-222 ykuO - - - - - - -
HEIKHJEJ_04050 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HEIKHJEJ_04051 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEIKHJEJ_04052 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEIKHJEJ_04053 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HEIKHJEJ_04054 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HEIKHJEJ_04055 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HEIKHJEJ_04056 4.23e-104 ykuV - - CO - - - thiol-disulfide
HEIKHJEJ_04057 4.71e-122 rok - - K - - - Repressor of ComK
HEIKHJEJ_04058 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEIKHJEJ_04059 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEIKHJEJ_04060 9.55e-88 yqhY - - S - - - protein conserved in bacteria
HEIKHJEJ_04061 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEIKHJEJ_04062 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEIKHJEJ_04063 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEIKHJEJ_04064 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEIKHJEJ_04065 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEIKHJEJ_04066 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEIKHJEJ_04067 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HEIKHJEJ_04068 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEIKHJEJ_04069 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEIKHJEJ_04070 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HEIKHJEJ_04071 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEIKHJEJ_04073 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEIKHJEJ_04074 4.74e-37 - - - - - - - -
HEIKHJEJ_04075 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HEIKHJEJ_04076 3.02e-171 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEIKHJEJ_04077 6.65e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEIKHJEJ_04078 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HEIKHJEJ_04079 7.33e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HEIKHJEJ_04080 6.46e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HEIKHJEJ_04081 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HEIKHJEJ_04082 3.58e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEIKHJEJ_04083 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HEIKHJEJ_04084 0.0 bkdR - - KT - - - Transcriptional regulator
HEIKHJEJ_04085 7.1e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HEIKHJEJ_04086 7.81e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HEIKHJEJ_04087 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HEIKHJEJ_04088 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEIKHJEJ_04089 1.58e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEIKHJEJ_04090 8.08e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEIKHJEJ_04091 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEIKHJEJ_04092 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HEIKHJEJ_04093 8.11e-222 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_04094 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEIKHJEJ_04095 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HEIKHJEJ_04096 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEIKHJEJ_04097 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HEIKHJEJ_04098 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HEIKHJEJ_04099 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HEIKHJEJ_04100 6.92e-128 yqjB - - S - - - protein conserved in bacteria
HEIKHJEJ_04102 7.75e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HEIKHJEJ_04103 1.61e-30 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEIKHJEJ_04104 7.25e-28 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEIKHJEJ_04105 1.36e-265 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEIKHJEJ_04106 3.04e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HEIKHJEJ_04107 4.5e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HEIKHJEJ_04108 3.93e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEIKHJEJ_04109 2.51e-32 yqzJ - - - - - - -
HEIKHJEJ_04110 5.26e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEIKHJEJ_04111 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEIKHJEJ_04112 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEIKHJEJ_04113 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEIKHJEJ_04114 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEIKHJEJ_04115 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEIKHJEJ_04116 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HEIKHJEJ_04117 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEIKHJEJ_04118 1.08e-139 tmrB - - S - - - AAA domain
HEIKHJEJ_04119 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEIKHJEJ_04120 2.99e-117 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HEIKHJEJ_04121 8.63e-97 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HEIKHJEJ_04122 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HEIKHJEJ_04123 1.33e-268 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEIKHJEJ_04124 2.38e-82 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HEIKHJEJ_04125 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEIKHJEJ_04126 7.37e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HEIKHJEJ_04127 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HEIKHJEJ_04128 7.79e-105 ycgB - - - - - - -
HEIKHJEJ_04129 0.0 ycgA - - S - - - Membrane
HEIKHJEJ_04130 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HEIKHJEJ_04131 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HEIKHJEJ_04132 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HEIKHJEJ_04133 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HEIKHJEJ_04134 1.38e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HEIKHJEJ_04135 1.19e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HEIKHJEJ_04136 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HEIKHJEJ_04137 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HEIKHJEJ_04139 5.37e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEIKHJEJ_04140 5.98e-72 ypuD - - - - - - -
HEIKHJEJ_04141 5.92e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEIKHJEJ_04142 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HEIKHJEJ_04143 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEIKHJEJ_04144 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEIKHJEJ_04145 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEIKHJEJ_04146 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HEIKHJEJ_04147 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEIKHJEJ_04148 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEIKHJEJ_04149 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HEIKHJEJ_04150 3.49e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HEIKHJEJ_04151 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HEIKHJEJ_04152 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEIKHJEJ_04153 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEIKHJEJ_04154 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEIKHJEJ_04155 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEIKHJEJ_04159 1.24e-22 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
HEIKHJEJ_04160 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEIKHJEJ_04161 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HEIKHJEJ_04163 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HEIKHJEJ_04164 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_04165 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_04166 4.47e-103 - - - T - - - HPP family
HEIKHJEJ_04167 2.23e-17 - - - S - - - CGNR zinc finger
HEIKHJEJ_04169 7.27e-55 - - - - - - - -
HEIKHJEJ_04170 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HEIKHJEJ_04171 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HEIKHJEJ_04174 4.67e-90 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HEIKHJEJ_04175 5.28e-83 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
HEIKHJEJ_04176 1.11e-111 yddI - - - - - - -
HEIKHJEJ_04177 2.82e-235 yddH - - M - - - Lysozyme-like
HEIKHJEJ_04178 1.56e-128 - - - - - - - -
HEIKHJEJ_04179 7.11e-181 yddG - - S - - - maturation of SSU-rRNA
HEIKHJEJ_04181 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
HEIKHJEJ_04183 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEIKHJEJ_04187 1.92e-47 - - - - - - - -
HEIKHJEJ_04188 2.28e-25 - - - - - - - -
HEIKHJEJ_04189 2.49e-07 - - - - - - - -
HEIKHJEJ_04190 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HEIKHJEJ_04191 2.43e-58 yjcN - - - - - - -
HEIKHJEJ_04192 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HEIKHJEJ_04193 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HEIKHJEJ_04194 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEIKHJEJ_04195 3.33e-72 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HEIKHJEJ_04196 1.51e-174 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HEIKHJEJ_04197 1.59e-65 - - - L - - - Transposase
HEIKHJEJ_04201 4.04e-39 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEIKHJEJ_04202 1.73e-13 - - - - - - - -
HEIKHJEJ_04203 3.96e-84 - - - O - - - Papain family cysteine protease
HEIKHJEJ_04205 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
HEIKHJEJ_04206 3.82e-37 - - - - - - - -
HEIKHJEJ_04208 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEIKHJEJ_04210 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HEIKHJEJ_04211 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEIKHJEJ_04221 3.99e-53 - - - - - - - -
HEIKHJEJ_04223 1.07e-57 - - - S - - - transposition, DNA-mediated
HEIKHJEJ_04224 1.82e-28 - - - S - - - HTH-like domain
HEIKHJEJ_04225 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HEIKHJEJ_04226 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HEIKHJEJ_04227 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEIKHJEJ_04228 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEIKHJEJ_04229 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEIKHJEJ_04230 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEIKHJEJ_04231 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HEIKHJEJ_04232 1.48e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HEIKHJEJ_04233 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HEIKHJEJ_04234 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HEIKHJEJ_04236 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEIKHJEJ_04237 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEIKHJEJ_04238 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEIKHJEJ_04239 1.24e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEIKHJEJ_04240 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEIKHJEJ_04241 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HEIKHJEJ_04242 2.14e-17 - - - Q - - - methyltransferase
HEIKHJEJ_04244 1.7e-118 yddD - - S - - - TcpE family
HEIKHJEJ_04245 9.78e-54 yddC - - - - - - -
HEIKHJEJ_04246 3.56e-95 yddB - - S - - - Conjugative transposon protein TcpC
HEIKHJEJ_04247 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HEIKHJEJ_04248 6.06e-136 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEIKHJEJ_04249 2.4e-60 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HEIKHJEJ_04250 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HEIKHJEJ_04251 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEIKHJEJ_04252 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEIKHJEJ_04253 3.03e-166 yodH - - Q - - - Methyltransferase
HEIKHJEJ_04254 4.86e-41 yodI - - - - - - -
HEIKHJEJ_04255 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HEIKHJEJ_04256 6.86e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HEIKHJEJ_04257 2.08e-12 - - - - - - - -
HEIKHJEJ_04258 1.17e-71 yodL - - S - - - YodL-like
HEIKHJEJ_04259 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HEIKHJEJ_04260 2.11e-33 yozD - - S - - - YozD-like protein
HEIKHJEJ_04262 7.44e-159 yodN - - - - - - -
HEIKHJEJ_04263 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HEIKHJEJ_04264 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HEIKHJEJ_04265 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HEIKHJEJ_04266 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HEIKHJEJ_04267 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HEIKHJEJ_04268 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEIKHJEJ_04270 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEIKHJEJ_04271 6.98e-279 - - - L - - - Transposase
HEIKHJEJ_04272 4.78e-152 - - - L - - - Bacterial dnaA protein
HEIKHJEJ_04273 3.3e-71 yneQ - - - - - - -
HEIKHJEJ_04274 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HEIKHJEJ_04275 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HEIKHJEJ_04277 9.26e-10 - - - S - - - Fur-regulated basic protein B
HEIKHJEJ_04278 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEIKHJEJ_04279 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEIKHJEJ_04280 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HEIKHJEJ_04281 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HEIKHJEJ_04282 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
HEIKHJEJ_04283 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HEIKHJEJ_04284 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HEIKHJEJ_04285 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HEIKHJEJ_04286 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HEIKHJEJ_04287 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HEIKHJEJ_04288 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HEIKHJEJ_04289 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HEIKHJEJ_04290 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEIKHJEJ_04291 1.15e-43 ynzC - - S - - - UPF0291 protein
HEIKHJEJ_04292 5.4e-143 yneB - - L - - - resolvase
HEIKHJEJ_04293 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEIKHJEJ_04294 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEIKHJEJ_04295 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEIKHJEJ_04296 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
HEIKHJEJ_04297 1.09e-173 yndL - - S - - - Replication protein
HEIKHJEJ_04300 0.0 yndJ - - S - - - YndJ-like protein
HEIKHJEJ_04301 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
HEIKHJEJ_04302 2.52e-196 yndG - - S - - - DoxX-like family
HEIKHJEJ_04303 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HEIKHJEJ_04304 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEIKHJEJ_04305 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HEIKHJEJ_04308 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HEIKHJEJ_04315 8.32e-151 ykwD - - J - - - protein with SCP PR1 domains
HEIKHJEJ_04316 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEIKHJEJ_04317 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_04318 4.65e-51 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEIKHJEJ_04319 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEIKHJEJ_04320 1.05e-22 - - - - - - - -
HEIKHJEJ_04321 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HEIKHJEJ_04322 3.71e-110 ykyB - - S - - - YkyB-like protein
HEIKHJEJ_04323 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HEIKHJEJ_04324 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HEIKHJEJ_04325 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HEIKHJEJ_04326 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
HEIKHJEJ_04327 2.21e-242 yddE - - S - - - AAA-like domain
HEIKHJEJ_04328 4.09e-128 yddE - - S - - - AAA-like domain
HEIKHJEJ_04329 3.29e-73 - - - S - - - Domain of unknown function (DUF1874)
HEIKHJEJ_04330 0.0 yddE - - S - - - AAA-like domain
HEIKHJEJ_04331 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEIKHJEJ_04334 7.54e-22 - - - - - - - -
HEIKHJEJ_04335 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HEIKHJEJ_04337 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEIKHJEJ_04338 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEIKHJEJ_04339 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HEIKHJEJ_04343 0.0 - - - V - - - Beta-lactamase
HEIKHJEJ_04345 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HEIKHJEJ_04347 4.82e-69 ynaF - - - - - - -
HEIKHJEJ_04348 7.47e-233 yaaC - - S - - - YaaC-like Protein
HEIKHJEJ_04349 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEIKHJEJ_04350 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEIKHJEJ_04351 2.45e-34 - - - K - - - Helix-turn-helix domain
HEIKHJEJ_04352 1.14e-20 - - - S - - - peptidoglycan catabolic process
HEIKHJEJ_04353 1.27e-07 - - - S - - - peptidoglycan catabolic process
HEIKHJEJ_04354 1.07e-25 - - - - - - - -
HEIKHJEJ_04356 2.43e-162 - - - S - - - Domain of unknown function, YrpD
HEIKHJEJ_04359 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HEIKHJEJ_04360 8.92e-96 - - - - - - - -
HEIKHJEJ_04363 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HEIKHJEJ_04364 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HEIKHJEJ_04365 2.78e-272 xylR - - GK - - - ROK family
HEIKHJEJ_04366 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)