ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NHAKPCLB_00001 3.84e-87 res - - L - - - Resolvase, N terminal domain
NHAKPCLB_00002 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
NHAKPCLB_00003 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
NHAKPCLB_00004 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
NHAKPCLB_00007 3.17e-170 - - - L - - - Phage integrase family
NHAKPCLB_00009 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NHAKPCLB_00010 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHAKPCLB_00011 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHAKPCLB_00012 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NHAKPCLB_00013 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NHAKPCLB_00014 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_00015 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_00016 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NHAKPCLB_00017 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NHAKPCLB_00018 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NHAKPCLB_00019 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NHAKPCLB_00020 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
NHAKPCLB_00021 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NHAKPCLB_00022 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHAKPCLB_00023 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NHAKPCLB_00024 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NHAKPCLB_00026 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NHAKPCLB_00027 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NHAKPCLB_00028 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NHAKPCLB_00029 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_00030 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHAKPCLB_00031 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
NHAKPCLB_00032 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHAKPCLB_00033 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NHAKPCLB_00034 3.12e-111 yshB - - S - - - membrane protein, required for colicin V production
NHAKPCLB_00035 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHAKPCLB_00036 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHAKPCLB_00037 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHAKPCLB_00038 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHAKPCLB_00039 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHAKPCLB_00040 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NHAKPCLB_00041 1.11e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NHAKPCLB_00042 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
NHAKPCLB_00043 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NHAKPCLB_00044 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
NHAKPCLB_00046 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NHAKPCLB_00047 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NHAKPCLB_00048 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NHAKPCLB_00049 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NHAKPCLB_00050 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NHAKPCLB_00051 1.24e-280 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NHAKPCLB_00052 5.81e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NHAKPCLB_00053 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NHAKPCLB_00054 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NHAKPCLB_00055 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NHAKPCLB_00056 5.69e-126 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_00057 4.74e-72 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_00058 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NHAKPCLB_00059 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
NHAKPCLB_00060 3.65e-59 ysdA - - S - - - Membrane
NHAKPCLB_00061 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHAKPCLB_00062 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NHAKPCLB_00063 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHAKPCLB_00065 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHAKPCLB_00066 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHAKPCLB_00067 4.62e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NHAKPCLB_00068 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_00069 1.15e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NHAKPCLB_00070 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHAKPCLB_00072 5.5e-202 ytxC - - S - - - YtxC-like family
NHAKPCLB_00073 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
NHAKPCLB_00074 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NHAKPCLB_00075 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NHAKPCLB_00076 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHAKPCLB_00077 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NHAKPCLB_00078 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHAKPCLB_00079 1.64e-86 ytcD - - K - - - Transcriptional regulator
NHAKPCLB_00080 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NHAKPCLB_00081 4.54e-205 ytbE - - S - - - reductase
NHAKPCLB_00082 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHAKPCLB_00083 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
NHAKPCLB_00084 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHAKPCLB_00085 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHAKPCLB_00086 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NHAKPCLB_00087 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00088 4.23e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NHAKPCLB_00089 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NHAKPCLB_00090 3.34e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NHAKPCLB_00091 4.46e-93 ytwI - - S - - - membrane
NHAKPCLB_00092 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
NHAKPCLB_00093 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NHAKPCLB_00094 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NHAKPCLB_00095 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHAKPCLB_00096 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHAKPCLB_00097 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHAKPCLB_00098 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NHAKPCLB_00099 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NHAKPCLB_00100 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
NHAKPCLB_00101 5.12e-112 ytrI - - - - - - -
NHAKPCLB_00102 1.15e-39 - - - - - - - -
NHAKPCLB_00103 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NHAKPCLB_00104 2.15e-63 ytpI - - S - - - YtpI-like protein
NHAKPCLB_00105 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
NHAKPCLB_00106 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NHAKPCLB_00107 5.71e-121 - - - M - - - FR47-like protein
NHAKPCLB_00108 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NHAKPCLB_00109 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NHAKPCLB_00110 6.53e-108 yuaE - - S - - - DinB superfamily
NHAKPCLB_00111 3.92e-135 yuaD - - - - - - -
NHAKPCLB_00112 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NHAKPCLB_00113 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NHAKPCLB_00114 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NHAKPCLB_00115 5.83e-118 yuaB - - - - - - -
NHAKPCLB_00116 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NHAKPCLB_00117 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
NHAKPCLB_00118 3.31e-52 yubF - - S - - - yiaA/B two helix domain
NHAKPCLB_00119 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHAKPCLB_00120 0.0 yubD - - P - - - Major Facilitator Superfamily
NHAKPCLB_00121 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
NHAKPCLB_00123 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHAKPCLB_00124 1.73e-252 yubA - - S - - - transporter activity
NHAKPCLB_00125 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NHAKPCLB_00126 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
NHAKPCLB_00127 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NHAKPCLB_00128 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NHAKPCLB_00129 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NHAKPCLB_00130 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
NHAKPCLB_00131 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00132 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00133 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00134 2.23e-199 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00135 4.17e-63 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00136 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00137 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NHAKPCLB_00138 2.04e-47 - - - - - - - -
NHAKPCLB_00139 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
NHAKPCLB_00140 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NHAKPCLB_00141 4.18e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NHAKPCLB_00142 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NHAKPCLB_00143 2.16e-48 - - - - - - - -
NHAKPCLB_00144 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
NHAKPCLB_00145 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NHAKPCLB_00146 4.22e-95 yugN - - S - - - YugN-like family
NHAKPCLB_00148 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NHAKPCLB_00149 1.26e-287 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NHAKPCLB_00150 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NHAKPCLB_00151 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NHAKPCLB_00152 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NHAKPCLB_00153 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NHAKPCLB_00154 6.74e-112 alaR - - K - - - Transcriptional regulator
NHAKPCLB_00155 9.89e-201 yugF - - I - - - Hydrolase
NHAKPCLB_00156 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
NHAKPCLB_00157 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHAKPCLB_00158 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_00159 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NHAKPCLB_00160 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NHAKPCLB_00162 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
NHAKPCLB_00163 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NHAKPCLB_00164 1.92e-97 yuxK - - S - - - protein conserved in bacteria
NHAKPCLB_00165 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
NHAKPCLB_00166 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NHAKPCLB_00167 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NHAKPCLB_00168 2.24e-251 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NHAKPCLB_00169 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00170 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHAKPCLB_00171 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHAKPCLB_00172 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
NHAKPCLB_00173 1.42e-21 - - - - - - - -
NHAKPCLB_00174 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHAKPCLB_00175 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHAKPCLB_00176 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHAKPCLB_00177 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHAKPCLB_00178 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHAKPCLB_00179 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHAKPCLB_00180 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NHAKPCLB_00181 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NHAKPCLB_00182 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_00183 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_00185 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NHAKPCLB_00186 6.29e-10 - - - S - - - DegQ (SacQ) family
NHAKPCLB_00187 8.73e-09 yuzC - - - - - - -
NHAKPCLB_00188 1.97e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NHAKPCLB_00189 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHAKPCLB_00190 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NHAKPCLB_00191 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
NHAKPCLB_00192 1.63e-52 yueH - - S - - - YueH-like protein
NHAKPCLB_00193 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NHAKPCLB_00194 1.35e-244 yueF - - S - - - transporter activity
NHAKPCLB_00195 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
NHAKPCLB_00196 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NHAKPCLB_00197 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_00198 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
NHAKPCLB_00199 0.0 yueB - - S - - - type VII secretion protein EsaA
NHAKPCLB_00200 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NHAKPCLB_00201 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NHAKPCLB_00202 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NHAKPCLB_00203 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
NHAKPCLB_00204 1.71e-291 yukF - - QT - - - Transcriptional regulator
NHAKPCLB_00205 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NHAKPCLB_00206 2.42e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NHAKPCLB_00207 8.23e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NHAKPCLB_00208 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_00209 1.82e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NHAKPCLB_00210 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NHAKPCLB_00211 1.22e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NHAKPCLB_00212 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_00213 2.18e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
NHAKPCLB_00214 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NHAKPCLB_00215 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NHAKPCLB_00216 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NHAKPCLB_00217 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NHAKPCLB_00218 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NHAKPCLB_00219 2.69e-150 yuiC - - S - - - protein conserved in bacteria
NHAKPCLB_00220 1.97e-46 yuiB - - S - - - Putative membrane protein
NHAKPCLB_00221 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHAKPCLB_00222 6.7e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NHAKPCLB_00224 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHAKPCLB_00225 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
NHAKPCLB_00226 2.31e-114 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_00228 0.0 - - - D - - - Phage tail tape measure protein
NHAKPCLB_00235 5.32e-26 - - - - - - - -
NHAKPCLB_00236 5.48e-110 - - - - - - - -
NHAKPCLB_00240 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHAKPCLB_00241 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_00242 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NHAKPCLB_00243 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHAKPCLB_00245 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NHAKPCLB_00246 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NHAKPCLB_00247 7.68e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NHAKPCLB_00248 2.91e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NHAKPCLB_00249 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NHAKPCLB_00251 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00254 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
NHAKPCLB_00258 1.23e-151 - - - K - - - Transcriptional regulator
NHAKPCLB_00259 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NHAKPCLB_00260 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NHAKPCLB_00261 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_00262 1.24e-198 degV - - S - - - protein conserved in bacteria
NHAKPCLB_00263 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHAKPCLB_00264 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NHAKPCLB_00265 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NHAKPCLB_00266 3.05e-95 yvyF - - S - - - flagellar protein
NHAKPCLB_00267 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NHAKPCLB_00268 7.06e-102 yvyG - - NOU - - - FlgN protein
NHAKPCLB_00269 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NHAKPCLB_00270 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NHAKPCLB_00271 6.92e-92 yviE - - - - - - -
NHAKPCLB_00272 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NHAKPCLB_00273 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NHAKPCLB_00274 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NHAKPCLB_00275 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
NHAKPCLB_00276 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NHAKPCLB_00277 1.48e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NHAKPCLB_00278 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NHAKPCLB_00279 2.46e-67 - - - - - - - -
NHAKPCLB_00280 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHAKPCLB_00281 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHAKPCLB_00282 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHAKPCLB_00283 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NHAKPCLB_00284 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NHAKPCLB_00285 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NHAKPCLB_00286 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHAKPCLB_00287 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NHAKPCLB_00288 1.38e-73 swrA - - S - - - Swarming motility protein
NHAKPCLB_00289 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHAKPCLB_00290 3.03e-295 yvkA - - P - - - -transporter
NHAKPCLB_00291 1.43e-131 yvkB - - K - - - Transcriptional regulator
NHAKPCLB_00292 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NHAKPCLB_00293 2.54e-42 csbA - - S - - - protein conserved in bacteria
NHAKPCLB_00294 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHAKPCLB_00295 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHAKPCLB_00296 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NHAKPCLB_00297 2.25e-45 yvkN - - - - - - -
NHAKPCLB_00298 8.09e-65 yvlA - - - - - - -
NHAKPCLB_00299 5.54e-219 yvlB - - S - - - Putative adhesin
NHAKPCLB_00300 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NHAKPCLB_00301 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NHAKPCLB_00302 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHAKPCLB_00303 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NHAKPCLB_00304 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NHAKPCLB_00305 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NHAKPCLB_00306 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NHAKPCLB_00307 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NHAKPCLB_00308 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NHAKPCLB_00309 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NHAKPCLB_00310 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NHAKPCLB_00311 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NHAKPCLB_00312 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00313 9.03e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_00314 6.59e-67 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00315 9.7e-88 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00316 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NHAKPCLB_00317 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
NHAKPCLB_00318 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_00319 1.13e-89 - - - - - - - -
NHAKPCLB_00320 2.66e-28 yxeD - - - - - - -
NHAKPCLB_00321 7.32e-42 yxeE - - - - - - -
NHAKPCLB_00324 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
NHAKPCLB_00325 3.87e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NHAKPCLB_00326 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHAKPCLB_00327 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_00328 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NHAKPCLB_00329 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NHAKPCLB_00330 1.13e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00331 2.89e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NHAKPCLB_00332 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
NHAKPCLB_00333 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
NHAKPCLB_00334 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
NHAKPCLB_00335 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHAKPCLB_00336 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHAKPCLB_00337 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHAKPCLB_00338 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NHAKPCLB_00339 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NHAKPCLB_00340 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHAKPCLB_00341 7.08e-307 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_00342 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
NHAKPCLB_00343 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHAKPCLB_00344 0.0 - - - L - - - HKD family nuclease
NHAKPCLB_00345 1.78e-35 - - - S - - - Domain of unknown function (DUF5082)
NHAKPCLB_00346 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
NHAKPCLB_00347 7.83e-269 - - - S - - - nuclease activity
NHAKPCLB_00349 1.83e-221 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
NHAKPCLB_00350 3.36e-68 - - - - - - - -
NHAKPCLB_00351 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_00352 2.15e-115 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHAKPCLB_00353 2.02e-217 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHAKPCLB_00354 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
NHAKPCLB_00355 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
NHAKPCLB_00356 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_00357 5.69e-208 yxxF - - EG - - - EamA-like transporter family
NHAKPCLB_00358 0.0 wapA - - M - - - COG3209 Rhs family protein
NHAKPCLB_00359 3.29e-19 yxiJ - - S - - - YxiJ-like protein
NHAKPCLB_00360 2.23e-99 wapA - - M - - - COG3209 Rhs family protein
NHAKPCLB_00361 1.27e-69 - - - - - - - -
NHAKPCLB_00363 6.44e-178 - - - - - - - -
NHAKPCLB_00364 5.36e-120 - - - S - - - Protein of unknown function (DUF4240)
NHAKPCLB_00365 7.13e-100 - - - - - - - -
NHAKPCLB_00366 4.48e-58 - - - - - - - -
NHAKPCLB_00367 4.67e-89 yxiG - - - - - - -
NHAKPCLB_00368 9.7e-68 yxxG - - - - - - -
NHAKPCLB_00369 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
NHAKPCLB_00372 8.22e-181 - - - - - - - -
NHAKPCLB_00373 1.01e-120 yxiI - - S - - - Protein of unknown function (DUF2716)
NHAKPCLB_00374 1.86e-40 - - - - - - - -
NHAKPCLB_00377 4.06e-58 yxiJ - - S - - - YxiJ-like protein
NHAKPCLB_00380 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
NHAKPCLB_00381 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NHAKPCLB_00382 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NHAKPCLB_00383 1.07e-142 - - - - - - - -
NHAKPCLB_00384 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NHAKPCLB_00385 7.21e-183 bglS - - M - - - licheninase activity
NHAKPCLB_00386 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NHAKPCLB_00387 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NHAKPCLB_00388 2.28e-63 yxiS - - - - - - -
NHAKPCLB_00389 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
NHAKPCLB_00390 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHAKPCLB_00391 2.42e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NHAKPCLB_00392 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NHAKPCLB_00393 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHAKPCLB_00394 3.99e-149 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHAKPCLB_00395 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NHAKPCLB_00396 3.66e-274 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NHAKPCLB_00397 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NHAKPCLB_00398 2.88e-111 yxjI - - S - - - LURP-one-related
NHAKPCLB_00401 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NHAKPCLB_00402 6.34e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
NHAKPCLB_00403 6.98e-243 - - - T - - - Signal transduction histidine kinase
NHAKPCLB_00404 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
NHAKPCLB_00405 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NHAKPCLB_00406 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHAKPCLB_00407 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHAKPCLB_00408 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NHAKPCLB_00409 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_00410 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
NHAKPCLB_00412 0.0 - - - O - - - Peptidase family M48
NHAKPCLB_00413 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
NHAKPCLB_00414 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NHAKPCLB_00415 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NHAKPCLB_00416 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NHAKPCLB_00417 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NHAKPCLB_00418 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHAKPCLB_00419 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NHAKPCLB_00420 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_00421 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
NHAKPCLB_00422 1.63e-39 - - - - - - - -
NHAKPCLB_00423 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
NHAKPCLB_00424 2.01e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00425 1.55e-176 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHAKPCLB_00426 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
NHAKPCLB_00427 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NHAKPCLB_00428 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NHAKPCLB_00429 1.05e-26 yxzF - - - - - - -
NHAKPCLB_00430 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NHAKPCLB_00431 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NHAKPCLB_00432 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHAKPCLB_00433 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_00434 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHAKPCLB_00435 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NHAKPCLB_00436 1.22e-81 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_00437 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_00438 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHAKPCLB_00439 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_00440 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NHAKPCLB_00441 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_00443 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NHAKPCLB_00444 9.78e-54 yddC - - - - - - -
NHAKPCLB_00445 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
NHAKPCLB_00449 4.39e-37 yddA - - - - - - -
NHAKPCLB_00451 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
NHAKPCLB_00455 1.5e-81 - - - S - - - Immunity protein 70
NHAKPCLB_00456 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NHAKPCLB_00457 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHAKPCLB_00458 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NHAKPCLB_00459 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NHAKPCLB_00460 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NHAKPCLB_00461 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHAKPCLB_00462 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00463 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00464 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_00465 2.06e-69 - - - - - - - -
NHAKPCLB_00466 3.95e-59 yhcC - - - - - - -
NHAKPCLB_00467 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
NHAKPCLB_00468 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NHAKPCLB_00469 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NHAKPCLB_00470 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NHAKPCLB_00471 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NHAKPCLB_00472 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NHAKPCLB_00473 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NHAKPCLB_00474 3.77e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NHAKPCLB_00475 5.64e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
NHAKPCLB_00476 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHAKPCLB_00477 9.27e-224 yhbB - - S - - - Putative amidase domain
NHAKPCLB_00478 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHAKPCLB_00479 8.77e-144 yhzB - - S - - - B3/4 domain
NHAKPCLB_00481 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_00482 3.81e-100 ygaO - - - - - - -
NHAKPCLB_00483 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHAKPCLB_00485 5.41e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NHAKPCLB_00486 1.13e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHAKPCLB_00487 2.82e-216 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NHAKPCLB_00488 2.58e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHAKPCLB_00489 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NHAKPCLB_00491 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NHAKPCLB_00492 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NHAKPCLB_00493 1.58e-36 - - - - - - - -
NHAKPCLB_00494 1.23e-182 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
NHAKPCLB_00511 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
NHAKPCLB_00513 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHAKPCLB_00515 9.49e-89 - - - - - - - -
NHAKPCLB_00516 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHAKPCLB_00518 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
NHAKPCLB_00519 4.42e-254 yycP - - - - - - -
NHAKPCLB_00520 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NHAKPCLB_00521 3.04e-110 yycN - - K - - - Acetyltransferase
NHAKPCLB_00522 8.7e-239 - - - S - - - aspartate phosphatase
NHAKPCLB_00524 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NHAKPCLB_00525 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NHAKPCLB_00526 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NHAKPCLB_00527 5.82e-20 - - - - - - - -
NHAKPCLB_00528 4.85e-119 - - - - - - - -
NHAKPCLB_00529 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
NHAKPCLB_00530 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NHAKPCLB_00531 2.31e-54 sdpR - - K - - - transcriptional
NHAKPCLB_00532 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NHAKPCLB_00533 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHAKPCLB_00534 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NHAKPCLB_00535 3.44e-200 yycI - - S - - - protein conserved in bacteria
NHAKPCLB_00536 0.0 yycH - - S - - - protein conserved in bacteria
NHAKPCLB_00537 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_00538 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00543 1.75e-312 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHAKPCLB_00544 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_00545 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NHAKPCLB_00546 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NHAKPCLB_00548 1.89e-22 yycC - - K - - - YycC-like protein
NHAKPCLB_00549 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NHAKPCLB_00550 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHAKPCLB_00551 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NHAKPCLB_00552 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NHAKPCLB_00553 1.5e-204 yybS - - S - - - membrane
NHAKPCLB_00555 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
NHAKPCLB_00556 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
NHAKPCLB_00557 1.3e-87 yybR - - K - - - Transcriptional regulator
NHAKPCLB_00558 1.4e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NHAKPCLB_00559 1.11e-90 - - - - - - - -
NHAKPCLB_00561 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_00562 9.88e-141 - - - K - - - TipAS antibiotic-recognition domain
NHAKPCLB_00563 2.05e-183 - - - - - - - -
NHAKPCLB_00564 2.39e-85 - - - S - - - SnoaL-like domain
NHAKPCLB_00565 2.81e-162 yybG - - S - - - Pentapeptide repeat-containing protein
NHAKPCLB_00566 6.02e-127 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_00567 2.04e-88 - - - S - - - Metallo-beta-lactamase superfamily
NHAKPCLB_00568 4.54e-100 yybA - - K - - - transcriptional
NHAKPCLB_00569 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
NHAKPCLB_00570 1.01e-123 yyaS - - S ko:K07149 - ko00000 Membrane
NHAKPCLB_00571 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NHAKPCLB_00572 1.5e-85 - - - S - - - YjbR
NHAKPCLB_00573 8.28e-135 yyaP - - H - - - RibD C-terminal domain
NHAKPCLB_00574 2.59e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NHAKPCLB_00575 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
NHAKPCLB_00576 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NHAKPCLB_00577 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHAKPCLB_00578 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
NHAKPCLB_00579 3.43e-81 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_00580 8.75e-26 - - - H - - - ThiF family
NHAKPCLB_00581 1.15e-30 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
NHAKPCLB_00582 3.58e-50 - - - EGP - - - PFAM Major Facilitator Superfamily
NHAKPCLB_00583 5.01e-78 ccpB - - K - - - Transcriptional regulator
NHAKPCLB_00584 1.15e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NHAKPCLB_00585 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHAKPCLB_00586 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHAKPCLB_00587 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NHAKPCLB_00588 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHAKPCLB_00589 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHAKPCLB_00590 7.41e-45 yyzM - - S - - - protein conserved in bacteria
NHAKPCLB_00591 5.34e-227 yyaD - - S - - - Membrane
NHAKPCLB_00592 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
NHAKPCLB_00593 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NHAKPCLB_00594 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NHAKPCLB_00595 3.77e-97 - - - S - - - Bacterial PH domain
NHAKPCLB_00596 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NHAKPCLB_00597 2.9e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NHAKPCLB_00598 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHAKPCLB_00599 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHAKPCLB_00600 2.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NHAKPCLB_00601 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHAKPCLB_00602 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHAKPCLB_00603 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHAKPCLB_00604 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHAKPCLB_00605 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NHAKPCLB_00606 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHAKPCLB_00607 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
NHAKPCLB_00608 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHAKPCLB_00609 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHAKPCLB_00610 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_00612 1.09e-34 - - - S - - - YCII-related domain
NHAKPCLB_00613 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NHAKPCLB_00614 1.35e-80 yjqA - - S - - - Bacterial PH domain
NHAKPCLB_00615 1.11e-138 yjqB - - S - - - Pfam:DUF867
NHAKPCLB_00616 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
NHAKPCLB_00617 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
NHAKPCLB_00618 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
NHAKPCLB_00620 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
NHAKPCLB_00621 4.14e-150 xkdC - - L - - - Bacterial dnaA protein
NHAKPCLB_00625 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NHAKPCLB_00626 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NHAKPCLB_00627 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NHAKPCLB_00628 0.0 yqbA - - S - - - portal protein
NHAKPCLB_00629 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
NHAKPCLB_00630 3.91e-217 xkdG - - S - - - Phage capsid family
NHAKPCLB_00631 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
NHAKPCLB_00632 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
NHAKPCLB_00633 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHAKPCLB_00634 2.36e-100 xkdJ - - - - - - -
NHAKPCLB_00635 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NHAKPCLB_00636 2.45e-98 xkdM - - S - - - Phage tail tube protein
NHAKPCLB_00637 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NHAKPCLB_00638 0.0 xkdO - - L - - - Transglycosylase SLT domain
NHAKPCLB_00639 1.73e-151 xkdP - - S - - - Lysin motif
NHAKPCLB_00640 2.31e-232 xkdQ - - G - - - NLP P60 protein
NHAKPCLB_00641 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
NHAKPCLB_00642 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
NHAKPCLB_00643 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NHAKPCLB_00644 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NHAKPCLB_00645 4.43e-56 - - - - - - - -
NHAKPCLB_00646 0.0 - - - - - - - -
NHAKPCLB_00647 2.7e-68 xkdW - - S - - - XkdW protein
NHAKPCLB_00648 6.35e-31 xkdX - - - - - - -
NHAKPCLB_00649 9.79e-195 xepA - - - - - - -
NHAKPCLB_00650 2.21e-51 xhlA - - S - - - Haemolysin XhlA
NHAKPCLB_00651 1.15e-52 xhlB - - S - - - SPP1 phage holin
NHAKPCLB_00652 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_00653 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NHAKPCLB_00654 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NHAKPCLB_00655 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
NHAKPCLB_00656 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NHAKPCLB_00657 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
NHAKPCLB_00658 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NHAKPCLB_00659 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHAKPCLB_00660 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NHAKPCLB_00662 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHAKPCLB_00663 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
NHAKPCLB_00664 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NHAKPCLB_00665 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_00666 1.23e-223 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_00667 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_00668 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NHAKPCLB_00670 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NHAKPCLB_00671 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NHAKPCLB_00672 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHAKPCLB_00673 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_00674 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NHAKPCLB_00675 9.79e-102 ykgA - - E - - - Amidinotransferase
NHAKPCLB_00676 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
NHAKPCLB_00677 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHAKPCLB_00678 9.93e-15 - - - - - - - -
NHAKPCLB_00679 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
NHAKPCLB_00680 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
NHAKPCLB_00681 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHAKPCLB_00682 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NHAKPCLB_00683 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NHAKPCLB_00684 2.76e-216 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NHAKPCLB_00685 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHAKPCLB_00686 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHAKPCLB_00687 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
NHAKPCLB_00688 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
NHAKPCLB_00689 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
NHAKPCLB_00690 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
NHAKPCLB_00691 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHAKPCLB_00692 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NHAKPCLB_00693 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHAKPCLB_00694 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NHAKPCLB_00695 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00696 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NHAKPCLB_00697 1.21e-142 ykoF - - S - - - YKOF-related Family
NHAKPCLB_00698 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00699 6.32e-309 ykoH - - T - - - Histidine kinase
NHAKPCLB_00700 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
NHAKPCLB_00701 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NHAKPCLB_00702 1.45e-08 - - - - - - - -
NHAKPCLB_00704 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NHAKPCLB_00705 1.49e-70 tnrA - - K - - - transcriptional
NHAKPCLB_00706 1.63e-25 - - - - - - - -
NHAKPCLB_00707 3.04e-36 ykoL - - - - - - -
NHAKPCLB_00708 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NHAKPCLB_00709 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NHAKPCLB_00710 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
NHAKPCLB_00711 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NHAKPCLB_00712 0.0 ykoS - - - - - - -
NHAKPCLB_00713 3.86e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NHAKPCLB_00714 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NHAKPCLB_00715 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NHAKPCLB_00716 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NHAKPCLB_00717 1.71e-143 ykoX - - S - - - membrane-associated protein
NHAKPCLB_00718 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NHAKPCLB_00719 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_00720 1.89e-211 rsgI - - S - - - Anti-sigma factor N-terminus
NHAKPCLB_00721 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NHAKPCLB_00722 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
NHAKPCLB_00723 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NHAKPCLB_00724 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NHAKPCLB_00725 4.85e-182 - - - Q - - - ubiE/COQ5 methyltransferase family
NHAKPCLB_00726 8.95e-225 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
NHAKPCLB_00727 7.75e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NHAKPCLB_00728 1.29e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NHAKPCLB_00729 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NHAKPCLB_00730 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHAKPCLB_00731 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHAKPCLB_00732 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NHAKPCLB_00733 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
NHAKPCLB_00734 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
NHAKPCLB_00735 7.22e-191 ycgS - - I - - - alpha/beta hydrolase fold
NHAKPCLB_00736 9.55e-242 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NHAKPCLB_00737 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NHAKPCLB_00738 3.45e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NHAKPCLB_00739 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHAKPCLB_00740 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHAKPCLB_00741 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NHAKPCLB_00742 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NHAKPCLB_00743 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
NHAKPCLB_00744 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
NHAKPCLB_00745 2.72e-141 yciC - - S - - - GTPases (G3E family)
NHAKPCLB_00746 2.26e-123 yciC - - S - - - GTPases (G3E family)
NHAKPCLB_00747 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NHAKPCLB_00748 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHAKPCLB_00751 1.11e-96 yckC - - S - - - membrane
NHAKPCLB_00752 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
NHAKPCLB_00753 1.06e-57 - - - K - - - MarR family
NHAKPCLB_00754 2.49e-27 - - - - - - - -
NHAKPCLB_00755 2.13e-113 - - - S - - - AAA domain
NHAKPCLB_00756 2.42e-27 - - - S - - - AAA domain
NHAKPCLB_00757 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHAKPCLB_00758 3.36e-91 nin - - S - - - Competence protein J (ComJ)
NHAKPCLB_00759 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
NHAKPCLB_00760 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00761 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_00762 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NHAKPCLB_00763 6.57e-136 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NHAKPCLB_00764 6.05e-86 hxlR - - K - - - transcriptional
NHAKPCLB_00765 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_00766 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_00767 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NHAKPCLB_00768 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NHAKPCLB_00769 5.99e-286 - - - EGP - - - Major Facilitator Superfamily
NHAKPCLB_00770 8.93e-124 - - - S - - - YcxB-like protein
NHAKPCLB_00771 3.27e-205 ycxC - - EG - - - EamA-like transporter family
NHAKPCLB_00772 2.81e-316 ycxD - - K - - - GntR family transcriptional regulator
NHAKPCLB_00773 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NHAKPCLB_00774 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
NHAKPCLB_00775 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NHAKPCLB_00776 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NHAKPCLB_00777 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NHAKPCLB_00778 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NHAKPCLB_00779 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NHAKPCLB_00780 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NHAKPCLB_00781 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NHAKPCLB_00782 6.45e-55 yclD - - - - - - -
NHAKPCLB_00783 1.84e-200 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
NHAKPCLB_00784 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NHAKPCLB_00785 0.0 yclG - - M - - - Pectate lyase superfamily protein
NHAKPCLB_00787 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NHAKPCLB_00788 8.22e-288 gerKC - - S ko:K06297 - ko00000 spore germination
NHAKPCLB_00789 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NHAKPCLB_00790 1.38e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NHAKPCLB_00791 5.33e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NHAKPCLB_00792 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00793 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHAKPCLB_00794 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NHAKPCLB_00796 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NHAKPCLB_00797 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NHAKPCLB_00798 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_00799 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_00800 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00801 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NHAKPCLB_00802 1.18e-96 - - - V - - - Restriction endonuclease
NHAKPCLB_00803 0.0 ycnB - - EGP - - - the major facilitator superfamily
NHAKPCLB_00804 5.87e-198 ycnC - - K - - - Transcriptional regulator
NHAKPCLB_00805 8.65e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NHAKPCLB_00806 1.68e-60 ycnE - - S - - - Monooxygenase
NHAKPCLB_00807 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHAKPCLB_00808 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_00809 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHAKPCLB_00810 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHAKPCLB_00811 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NHAKPCLB_00812 1.39e-185 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_00813 1.34e-132 ycnI - - S - - - protein conserved in bacteria
NHAKPCLB_00814 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NHAKPCLB_00815 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NHAKPCLB_00816 1.34e-74 - - - - - - - -
NHAKPCLB_00817 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NHAKPCLB_00818 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NHAKPCLB_00819 3.1e-268 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NHAKPCLB_00820 3.39e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NHAKPCLB_00822 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHAKPCLB_00823 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
NHAKPCLB_00824 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NHAKPCLB_00826 3.15e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NHAKPCLB_00827 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NHAKPCLB_00828 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NHAKPCLB_00829 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NHAKPCLB_00830 2.8e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NHAKPCLB_00831 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NHAKPCLB_00832 1.55e-170 kipR - - K - - - Transcriptional regulator
NHAKPCLB_00833 1.2e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NHAKPCLB_00835 8.97e-65 yczJ - - S - - - biosynthesis
NHAKPCLB_00836 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NHAKPCLB_00837 3.5e-219 ycsN - - S - - - Oxidoreductase
NHAKPCLB_00838 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NHAKPCLB_00839 0.0 ydaB - - IQ - - - acyl-CoA ligase
NHAKPCLB_00840 1e-127 ydaC - - Q - - - Methyltransferase domain
NHAKPCLB_00841 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_00842 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NHAKPCLB_00843 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHAKPCLB_00844 6.13e-100 ydaG - - S - - - general stress protein
NHAKPCLB_00845 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NHAKPCLB_00846 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NHAKPCLB_00847 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NHAKPCLB_00848 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHAKPCLB_00849 8.17e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NHAKPCLB_00850 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NHAKPCLB_00852 1.84e-34 - - - - - - - -
NHAKPCLB_00853 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
NHAKPCLB_00855 6.14e-53 - - - - - - - -
NHAKPCLB_00856 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NHAKPCLB_00857 1.67e-42 ydaS - - S - - - membrane
NHAKPCLB_00858 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NHAKPCLB_00859 4.3e-190 ydbA - - P - - - EcsC protein family
NHAKPCLB_00860 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
NHAKPCLB_00861 2.17e-78 ydbB - - G - - - Cupin domain
NHAKPCLB_00862 3.66e-82 ydbC - - S - - - Domain of unknown function (DUF4937
NHAKPCLB_00863 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
NHAKPCLB_00864 6.07e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NHAKPCLB_00865 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NHAKPCLB_00866 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NHAKPCLB_00867 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHAKPCLB_00868 5.38e-230 ydbI - - S - - - AI-2E family transporter
NHAKPCLB_00869 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00870 4.95e-158 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHAKPCLB_00871 9.32e-70 ydbL - - - - - - -
NHAKPCLB_00872 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
NHAKPCLB_00873 1.49e-26 - - - S - - - Fur-regulated basic protein B
NHAKPCLB_00874 2.1e-11 - - - S - - - Fur-regulated basic protein A
NHAKPCLB_00875 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHAKPCLB_00876 4.19e-75 ydbP - - CO - - - Thioredoxin
NHAKPCLB_00877 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NHAKPCLB_00878 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHAKPCLB_00879 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHAKPCLB_00880 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NHAKPCLB_00881 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NHAKPCLB_00882 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NHAKPCLB_00883 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHAKPCLB_00884 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NHAKPCLB_00885 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHAKPCLB_00886 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NHAKPCLB_00887 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NHAKPCLB_00888 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NHAKPCLB_00889 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NHAKPCLB_00890 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NHAKPCLB_00891 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NHAKPCLB_00892 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NHAKPCLB_00893 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NHAKPCLB_00894 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_00895 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NHAKPCLB_00898 4.42e-105 ydcG - - S - - - EVE domain
NHAKPCLB_00899 1.79e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_00900 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NHAKPCLB_00901 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NHAKPCLB_00909 5.14e-269 ydcL - - L - - - Belongs to the 'phage' integrase family
NHAKPCLB_00910 1.65e-118 - - - E - - - IrrE N-terminal-like domain
NHAKPCLB_00911 1.91e-81 - - - K - - - Transcriptional
NHAKPCLB_00912 8.96e-24 - - - - - - - -
NHAKPCLB_00913 1.35e-55 - - - - - - - -
NHAKPCLB_00915 1.84e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
NHAKPCLB_00916 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
NHAKPCLB_00917 2.58e-254 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NHAKPCLB_00918 2.68e-23 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
NHAKPCLB_00921 2.49e-63 yddA - - - - - - -
NHAKPCLB_00922 1.29e-223 yddB - - S - - - Conjugative transposon protein TcpC
NHAKPCLB_00923 9.78e-54 yddC - - - - - - -
NHAKPCLB_00924 0.0 - - - - - - - -
NHAKPCLB_00925 7.54e-92 - - - L - - - Prophage endopeptidase tail
NHAKPCLB_00926 1.37e-67 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NHAKPCLB_00927 9.06e-135 - - - D - - - phage tail tape measure protein
NHAKPCLB_00929 7.39e-33 - - - - - - - -
NHAKPCLB_00930 1.56e-65 - - - N - - - domain, Protein
NHAKPCLB_00931 7.61e-40 - - - - - - - -
NHAKPCLB_00932 4.04e-22 - - - - - - - -
NHAKPCLB_00933 2.82e-34 - - - - - - - -
NHAKPCLB_00935 1.74e-102 - - - - - - - -
NHAKPCLB_00936 4.51e-08 - - - S - - - Domain of unknown function (DUF4355)
NHAKPCLB_00937 2.45e-106 - - - S - - - Phage minor capsid protein 2
NHAKPCLB_00938 1.27e-192 - - - - - - - -
NHAKPCLB_00939 7.57e-31 - - - S - - - Helix-turn-helix of insertion element transposase
NHAKPCLB_00940 5.35e-169 - - - S - - - TIGRFAM Phage uncharacterised protein, C-terminal
NHAKPCLB_00941 1.12e-86 - - - L - - - Phage integrase family
NHAKPCLB_00942 3.04e-11 - - - - - - - -
NHAKPCLB_00945 2.14e-51 - - - - - - - -
NHAKPCLB_00948 4.34e-30 - - - K - - - Sigma-70, region 4
NHAKPCLB_00954 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_00955 1.64e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NHAKPCLB_00956 5.85e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NHAKPCLB_00957 1.01e-64 yvaD - - S - - - Family of unknown function (DUF5360)
NHAKPCLB_00958 0.0 - - - S - - - Fusaric acid resistance protein-like
NHAKPCLB_00959 4.87e-34 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHAKPCLB_00960 8.02e-107 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHAKPCLB_00961 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NHAKPCLB_00962 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NHAKPCLB_00963 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
NHAKPCLB_00964 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NHAKPCLB_00965 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NHAKPCLB_00966 3.45e-137 bdbD - - O - - - Thioredoxin
NHAKPCLB_00967 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NHAKPCLB_00968 2.34e-139 yvgT - - S - - - membrane
NHAKPCLB_00970 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHAKPCLB_00971 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHAKPCLB_00972 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NHAKPCLB_00973 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NHAKPCLB_00974 9.32e-112 yvgO - - - - - - -
NHAKPCLB_00975 7.23e-200 yvgN - - S - - - reductase
NHAKPCLB_00976 1.74e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NHAKPCLB_00977 6.03e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NHAKPCLB_00978 3.46e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NHAKPCLB_00979 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NHAKPCLB_00980 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NHAKPCLB_00981 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NHAKPCLB_00982 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NHAKPCLB_00983 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_00984 3.87e-233 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_00985 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_00986 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHAKPCLB_00987 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
NHAKPCLB_00988 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_00989 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NHAKPCLB_00990 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
NHAKPCLB_00991 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NHAKPCLB_00992 3.46e-26 - - - S - - - YvrJ protein family
NHAKPCLB_00993 6.67e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NHAKPCLB_00994 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_00995 0.0 yvrG - - T - - - Histidine kinase
NHAKPCLB_00996 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NHAKPCLB_00997 1.01e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_00998 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHAKPCLB_00999 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_01000 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NHAKPCLB_01001 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NHAKPCLB_01002 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_01003 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NHAKPCLB_01004 1.41e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NHAKPCLB_01005 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NHAKPCLB_01006 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NHAKPCLB_01007 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_01008 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_01009 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NHAKPCLB_01010 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NHAKPCLB_01011 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NHAKPCLB_01012 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
NHAKPCLB_01013 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHAKPCLB_01014 3.06e-204 yuxN - - K - - - Transcriptional regulator
NHAKPCLB_01015 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_01016 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_01017 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHAKPCLB_01018 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NHAKPCLB_01019 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_01020 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHAKPCLB_01021 1.26e-18 - - - - - - - -
NHAKPCLB_01023 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
NHAKPCLB_01025 2.94e-17 - - - EGP - - - Major Facilitator
NHAKPCLB_01026 6.4e-09 - - - J - - - O-methyltransferase
NHAKPCLB_01027 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
NHAKPCLB_01028 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NHAKPCLB_01030 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NHAKPCLB_01031 3.48e-88 - - - S - - - YusW-like protein
NHAKPCLB_01032 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHAKPCLB_01033 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
NHAKPCLB_01034 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NHAKPCLB_01035 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_01036 4.86e-84 yusQ - - S - - - Tautomerase enzyme
NHAKPCLB_01037 0.0 yusP - - P - - - Major facilitator superfamily
NHAKPCLB_01038 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NHAKPCLB_01039 8.66e-70 yusN - - M - - - Coat F domain
NHAKPCLB_01040 2.23e-54 - - - - - - - -
NHAKPCLB_01041 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NHAKPCLB_01042 1.11e-13 - - - S - - - YuzL-like protein
NHAKPCLB_01043 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NHAKPCLB_01044 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NHAKPCLB_01045 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NHAKPCLB_01046 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NHAKPCLB_01047 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NHAKPCLB_01048 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
NHAKPCLB_01049 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NHAKPCLB_01050 8.14e-73 yusE - - CO - - - Thioredoxin
NHAKPCLB_01051 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
NHAKPCLB_01052 1.76e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHAKPCLB_01053 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NHAKPCLB_01054 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NHAKPCLB_01055 6.44e-62 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHAKPCLB_01056 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHAKPCLB_01057 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NHAKPCLB_01058 1.63e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHAKPCLB_01059 1.79e-100 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NHAKPCLB_01060 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NHAKPCLB_01061 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHAKPCLB_01062 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_01063 3.35e-56 - - - - - - - -
NHAKPCLB_01065 3.9e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NHAKPCLB_01066 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NHAKPCLB_01067 3.71e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NHAKPCLB_01068 1e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NHAKPCLB_01069 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHAKPCLB_01070 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NHAKPCLB_01071 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NHAKPCLB_01072 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NHAKPCLB_01073 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NHAKPCLB_01074 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_01075 7.63e-217 bsn - - L - - - Ribonuclease
NHAKPCLB_01076 6.85e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHAKPCLB_01077 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NHAKPCLB_01078 5.27e-236 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NHAKPCLB_01079 8.43e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NHAKPCLB_01080 6.07e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NHAKPCLB_01081 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NHAKPCLB_01082 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NHAKPCLB_01083 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NHAKPCLB_01084 8.84e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NHAKPCLB_01085 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NHAKPCLB_01086 3.71e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NHAKPCLB_01087 1.7e-297 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
NHAKPCLB_01088 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NHAKPCLB_01089 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NHAKPCLB_01090 3.06e-79 yunG - - - - - - -
NHAKPCLB_01091 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
NHAKPCLB_01092 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NHAKPCLB_01093 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NHAKPCLB_01094 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
NHAKPCLB_01095 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NHAKPCLB_01096 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NHAKPCLB_01097 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHAKPCLB_01098 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHAKPCLB_01099 3.2e-63 yutD - - S - - - protein conserved in bacteria
NHAKPCLB_01100 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
NHAKPCLB_01101 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHAKPCLB_01102 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NHAKPCLB_01103 1.55e-253 yutH - - S - - - Spore coat protein
NHAKPCLB_01104 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NHAKPCLB_01105 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NHAKPCLB_01106 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHAKPCLB_01107 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NHAKPCLB_01108 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NHAKPCLB_01109 5.44e-74 yuzD - - S - - - protein conserved in bacteria
NHAKPCLB_01110 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHAKPCLB_01111 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NHAKPCLB_01112 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHAKPCLB_01113 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHAKPCLB_01114 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NHAKPCLB_01115 7.01e-128 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
NHAKPCLB_01116 3.64e-138 - - - S - - - Helix-turn-helix domain
NHAKPCLB_01117 1.36e-87 - - - L - - - Integrase
NHAKPCLB_01118 1.04e-05 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHAKPCLB_01121 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NHAKPCLB_01122 1.79e-84 ydjM - - M - - - Lytic transglycolase
NHAKPCLB_01123 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NHAKPCLB_01124 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_01125 1.53e-245 - - - S - - - Ion transport 2 domain protein
NHAKPCLB_01126 5.98e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NHAKPCLB_01127 1.48e-172 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NHAKPCLB_01128 1.42e-225 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHAKPCLB_01129 8.87e-76 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NHAKPCLB_01130 3.64e-59 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NHAKPCLB_01131 1.22e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NHAKPCLB_01132 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NHAKPCLB_01133 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NHAKPCLB_01134 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NHAKPCLB_01135 5.53e-175 - - - - - - - -
NHAKPCLB_01136 1.17e-148 - - - - - - - -
NHAKPCLB_01138 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHAKPCLB_01139 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHAKPCLB_01140 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NHAKPCLB_01141 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NHAKPCLB_01142 8.36e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHAKPCLB_01143 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHAKPCLB_01144 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHAKPCLB_01145 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NHAKPCLB_01146 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NHAKPCLB_01147 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHAKPCLB_01148 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHAKPCLB_01149 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NHAKPCLB_01150 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NHAKPCLB_01151 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHAKPCLB_01154 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
NHAKPCLB_01155 3.28e-181 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_01157 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NHAKPCLB_01158 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHAKPCLB_01159 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NHAKPCLB_01160 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHAKPCLB_01161 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NHAKPCLB_01162 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHAKPCLB_01163 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
NHAKPCLB_01164 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
NHAKPCLB_01165 2.36e-111 yteJ - - S - - - RDD family
NHAKPCLB_01166 4.62e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NHAKPCLB_01167 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHAKPCLB_01168 0.0 ytcJ - - S - - - amidohydrolase
NHAKPCLB_01169 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHAKPCLB_01170 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NHAKPCLB_01171 8.89e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHAKPCLB_01172 2.74e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NHAKPCLB_01173 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHAKPCLB_01174 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHAKPCLB_01175 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NHAKPCLB_01176 9.83e-141 yttP - - K - - - Transcriptional regulator
NHAKPCLB_01177 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NHAKPCLB_01178 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NHAKPCLB_01179 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHAKPCLB_01181 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHAKPCLB_01182 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHAKPCLB_01183 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NHAKPCLB_01184 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NHAKPCLB_01185 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NHAKPCLB_01186 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NHAKPCLB_01187 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NHAKPCLB_01188 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NHAKPCLB_01189 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NHAKPCLB_01190 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
NHAKPCLB_01191 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NHAKPCLB_01192 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHAKPCLB_01193 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NHAKPCLB_01194 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NHAKPCLB_01195 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHAKPCLB_01196 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
NHAKPCLB_01197 3.17e-75 ytpP - - CO - - - Thioredoxin
NHAKPCLB_01198 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NHAKPCLB_01199 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NHAKPCLB_01200 6.75e-67 ytzB - - S - - - small secreted protein
NHAKPCLB_01201 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NHAKPCLB_01202 3.18e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NHAKPCLB_01203 4.36e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHAKPCLB_01204 9.51e-61 ytzH - - S - - - YtzH-like protein
NHAKPCLB_01205 3.02e-192 ytmP - - M - - - Phosphotransferase
NHAKPCLB_01206 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NHAKPCLB_01207 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NHAKPCLB_01208 4.92e-212 ytlQ - - - - - - -
NHAKPCLB_01209 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NHAKPCLB_01210 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NHAKPCLB_01211 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NHAKPCLB_01212 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NHAKPCLB_01213 2.89e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NHAKPCLB_01214 4.65e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHAKPCLB_01215 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NHAKPCLB_01216 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NHAKPCLB_01217 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_01218 1.16e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NHAKPCLB_01219 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NHAKPCLB_01220 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NHAKPCLB_01221 9.57e-98 yteU - - S - - - Integral membrane protein
NHAKPCLB_01222 1.83e-251 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NHAKPCLB_01223 2.27e-92 yteS - - G - - - transport
NHAKPCLB_01224 4.8e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NHAKPCLB_01225 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NHAKPCLB_01226 1.36e-202 ytdP - - K - - - Transcriptional regulator
NHAKPCLB_01227 5.52e-276 ytdP - - K - - - Transcriptional regulator
NHAKPCLB_01228 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NHAKPCLB_01229 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NHAKPCLB_01230 1.05e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
NHAKPCLB_01231 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NHAKPCLB_01232 1.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NHAKPCLB_01233 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NHAKPCLB_01234 2.83e-256 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHAKPCLB_01235 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NHAKPCLB_01236 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NHAKPCLB_01237 1.67e-221 - - - S - - - Acetyl xylan esterase (AXE1)
NHAKPCLB_01238 2.08e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_01239 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHAKPCLB_01240 1.77e-198 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_01241 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NHAKPCLB_01242 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NHAKPCLB_01243 1.22e-68 ytwF - - P - - - Sulfurtransferase
NHAKPCLB_01244 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NHAKPCLB_01245 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
NHAKPCLB_01246 1.49e-180 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NHAKPCLB_01247 4.05e-267 yttB - - EGP - - - Major facilitator superfamily
NHAKPCLB_01248 5.75e-78 yttA - - S - - - Pfam Transposase IS66
NHAKPCLB_01249 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NHAKPCLB_01250 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_01251 1.3e-238 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NHAKPCLB_01252 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_01253 2.69e-294 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NHAKPCLB_01254 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_01255 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NHAKPCLB_01256 4.66e-213 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_01257 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_01258 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NHAKPCLB_01260 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
NHAKPCLB_01261 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NHAKPCLB_01262 2.75e-136 ytqB - - J - - - Putative rRNA methylase
NHAKPCLB_01263 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NHAKPCLB_01264 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NHAKPCLB_01265 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHAKPCLB_01266 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_01267 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NHAKPCLB_01268 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHAKPCLB_01269 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NHAKPCLB_01270 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
NHAKPCLB_01271 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NHAKPCLB_01272 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHAKPCLB_01273 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NHAKPCLB_01274 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHAKPCLB_01275 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NHAKPCLB_01276 1.59e-81 ytkC - - S - - - Bacteriophage holin family
NHAKPCLB_01277 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NHAKPCLB_01279 6.79e-95 ytkA - - S - - - YtkA-like
NHAKPCLB_01280 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHAKPCLB_01281 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NHAKPCLB_01282 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NHAKPCLB_01283 3e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NHAKPCLB_01284 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NHAKPCLB_01285 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NHAKPCLB_01286 7.59e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NHAKPCLB_01287 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHAKPCLB_01288 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHAKPCLB_01289 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHAKPCLB_01290 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NHAKPCLB_01291 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHAKPCLB_01292 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHAKPCLB_01293 4.49e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NHAKPCLB_01294 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NHAKPCLB_01295 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NHAKPCLB_01296 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
NHAKPCLB_01297 2.32e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NHAKPCLB_01298 6.8e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHAKPCLB_01299 7.97e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
NHAKPCLB_01300 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
NHAKPCLB_01302 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
NHAKPCLB_01303 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
NHAKPCLB_01304 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
NHAKPCLB_01305 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NHAKPCLB_01306 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHAKPCLB_01307 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHAKPCLB_01308 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
NHAKPCLB_01309 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHAKPCLB_01310 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHAKPCLB_01332 0.000711 - - - - - - - -
NHAKPCLB_01335 6.04e-78 - - - L - - - Phage integrase family
NHAKPCLB_01336 7.89e-68 - - - M - - - ArpU family transcriptional regulator
NHAKPCLB_01338 1.12e-07 - - - S - - - YopX protein
NHAKPCLB_01340 6.17e-60 - - - S - - - dUTPase
NHAKPCLB_01346 2.78e-08 - - - - - - - -
NHAKPCLB_01349 1.76e-10 - - - - - - - -
NHAKPCLB_01350 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NHAKPCLB_01351 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NHAKPCLB_01354 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NHAKPCLB_01355 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
NHAKPCLB_01358 5.28e-79 - - - - - - - -
NHAKPCLB_01359 4.26e-43 - - - S - - - Phage integrase family
NHAKPCLB_01360 2.09e-81 - - - S - - - Phage integrase family
NHAKPCLB_01362 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NHAKPCLB_01363 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHAKPCLB_01364 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NHAKPCLB_01365 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NHAKPCLB_01366 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
NHAKPCLB_01367 4.9e-48 yvzC - - K - - - transcriptional
NHAKPCLB_01368 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NHAKPCLB_01369 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NHAKPCLB_01370 3.85e-72 yvaP - - K - - - transcriptional
NHAKPCLB_01371 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_01372 9.2e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NHAKPCLB_01373 1.13e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHAKPCLB_01374 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NHAKPCLB_01375 1.73e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHAKPCLB_01376 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NHAKPCLB_01377 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NHAKPCLB_01378 6.08e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHAKPCLB_01379 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NHAKPCLB_01380 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHAKPCLB_01381 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NHAKPCLB_01382 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NHAKPCLB_01383 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
NHAKPCLB_01384 2.66e-155 yvbI - - M - - - Membrane
NHAKPCLB_01385 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NHAKPCLB_01386 1.18e-97 yvbK - - K - - - acetyltransferase
NHAKPCLB_01387 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHAKPCLB_01388 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NHAKPCLB_01389 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHAKPCLB_01390 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NHAKPCLB_01391 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHAKPCLB_01392 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHAKPCLB_01393 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_01394 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NHAKPCLB_01395 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHAKPCLB_01396 1.99e-205 yvbU - - K - - - Transcriptional regulator
NHAKPCLB_01397 5.59e-198 yvbV - - EG - - - EamA-like transporter family
NHAKPCLB_01398 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_01399 2.7e-187 - - - S - - - Glycosyl hydrolase
NHAKPCLB_01400 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHAKPCLB_01401 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NHAKPCLB_01402 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHAKPCLB_01403 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_01404 5.39e-252 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_01405 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NHAKPCLB_01406 5.7e-207 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NHAKPCLB_01407 8.25e-33 - 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 AAA domain
NHAKPCLB_01408 3.23e-178 - - - M - - - -acetyltransferase
NHAKPCLB_01409 1.15e-66 - - - S - - - ASCH
NHAKPCLB_01410 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
NHAKPCLB_01411 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
NHAKPCLB_01412 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NHAKPCLB_01413 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
NHAKPCLB_01414 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NHAKPCLB_01415 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NHAKPCLB_01416 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NHAKPCLB_01417 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_01418 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NHAKPCLB_01419 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NHAKPCLB_01420 4.25e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NHAKPCLB_01421 5.69e-44 yvfG - - S - - - YvfG protein
NHAKPCLB_01422 5.09e-239 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NHAKPCLB_01423 1.5e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NHAKPCLB_01424 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NHAKPCLB_01425 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHAKPCLB_01426 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_01427 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NHAKPCLB_01428 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NHAKPCLB_01429 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NHAKPCLB_01430 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NHAKPCLB_01431 1.19e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHAKPCLB_01432 6.94e-199 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NHAKPCLB_01433 2.49e-278 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NHAKPCLB_01434 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NHAKPCLB_01435 1.6e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NHAKPCLB_01436 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NHAKPCLB_01437 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NHAKPCLB_01438 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NHAKPCLB_01440 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NHAKPCLB_01441 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
NHAKPCLB_01442 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
NHAKPCLB_01443 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NHAKPCLB_01444 2.17e-224 pbpE - - V - - - Beta-lactamase
NHAKPCLB_01445 3.77e-79 pbpE - - V - - - Beta-lactamase
NHAKPCLB_01446 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NHAKPCLB_01447 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NHAKPCLB_01448 0.0 ybeC - - E - - - amino acid
NHAKPCLB_01449 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
NHAKPCLB_01450 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NHAKPCLB_01451 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NHAKPCLB_01452 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
NHAKPCLB_01453 3.28e-29 - - - K - - - Helix-turn-helix
NHAKPCLB_01455 2.94e-166 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
NHAKPCLB_01456 1.27e-83 - - - - - - - -
NHAKPCLB_01458 7.35e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
NHAKPCLB_01459 2.24e-192 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NHAKPCLB_01460 1.85e-40 - - - S - - - BhlA holin family
NHAKPCLB_01462 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHAKPCLB_01463 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NHAKPCLB_01464 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
NHAKPCLB_01465 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHAKPCLB_01466 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NHAKPCLB_01468 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHAKPCLB_01469 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHAKPCLB_01470 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NHAKPCLB_01471 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NHAKPCLB_01472 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHAKPCLB_01473 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHAKPCLB_01474 3.57e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NHAKPCLB_01475 5.41e-311 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
NHAKPCLB_01476 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NHAKPCLB_01477 1.05e-255 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NHAKPCLB_01478 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_01479 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
NHAKPCLB_01480 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NHAKPCLB_01481 9.23e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHAKPCLB_01482 2.29e-29 ywtC - - - - - - -
NHAKPCLB_01483 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NHAKPCLB_01484 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NHAKPCLB_01485 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NHAKPCLB_01486 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
NHAKPCLB_01487 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHAKPCLB_01488 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHAKPCLB_01489 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NHAKPCLB_01490 1.59e-201 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NHAKPCLB_01491 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NHAKPCLB_01492 3.97e-119 batE - - T - - - Sh3 type 3 domain protein
NHAKPCLB_01493 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
NHAKPCLB_01494 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NHAKPCLB_01495 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NHAKPCLB_01496 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NHAKPCLB_01497 1.37e-217 alsR - - K - - - LysR substrate binding domain
NHAKPCLB_01498 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHAKPCLB_01499 4.33e-162 ywrJ - - - - - - -
NHAKPCLB_01500 7.86e-162 cotB - - - ko:K06325 - ko00000 -
NHAKPCLB_01501 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
NHAKPCLB_01502 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHAKPCLB_01503 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
NHAKPCLB_01504 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NHAKPCLB_01505 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NHAKPCLB_01506 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NHAKPCLB_01507 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NHAKPCLB_01509 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
NHAKPCLB_01510 4.73e-209 - - - K - - - Transcriptional regulator
NHAKPCLB_01511 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NHAKPCLB_01513 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
NHAKPCLB_01514 4.93e-95 ywqJ - - S - - - Pre-toxin TG
NHAKPCLB_01515 1.3e-23 - - - - - - - -
NHAKPCLB_01516 2.5e-26 - - - - - - - -
NHAKPCLB_01517 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NHAKPCLB_01518 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
NHAKPCLB_01520 1.45e-108 ywqG - - S - - - Domain of unknown function (DUF1963)
NHAKPCLB_01521 1.3e-38 ywqG - - S - - - Domain of unknown function (DUF1963)
NHAKPCLB_01522 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHAKPCLB_01523 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NHAKPCLB_01524 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NHAKPCLB_01525 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NHAKPCLB_01526 3.6e-25 - - - - - - - -
NHAKPCLB_01527 0.0 ywqB - - S - - - SWIM zinc finger
NHAKPCLB_01528 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHAKPCLB_01529 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NHAKPCLB_01530 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NHAKPCLB_01531 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NHAKPCLB_01532 2.79e-40 ywpG - - - - - - -
NHAKPCLB_01533 3.59e-88 ywpF - - S - - - YwpF-like protein
NHAKPCLB_01534 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NHAKPCLB_01535 4.66e-186 ywpD - - T - - - Histidine kinase
NHAKPCLB_01536 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHAKPCLB_01537 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHAKPCLB_01538 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NHAKPCLB_01539 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NHAKPCLB_01540 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NHAKPCLB_01541 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NHAKPCLB_01542 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NHAKPCLB_01543 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
NHAKPCLB_01544 3.21e-268 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_01545 1.14e-309 ywoF - - P - - - Right handed beta helix region
NHAKPCLB_01546 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NHAKPCLB_01547 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
NHAKPCLB_01548 3e-133 yjgF - - Q - - - Isochorismatase family
NHAKPCLB_01549 7.16e-101 - - - - - - - -
NHAKPCLB_01550 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NHAKPCLB_01551 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NHAKPCLB_01552 1.72e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NHAKPCLB_01553 9.05e-93 ywnJ - - S - - - VanZ like family
NHAKPCLB_01554 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NHAKPCLB_01555 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NHAKPCLB_01556 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
NHAKPCLB_01557 6.7e-234 - - - M - - - NeuB family
NHAKPCLB_01558 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
NHAKPCLB_01559 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHAKPCLB_01560 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NHAKPCLB_01561 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
NHAKPCLB_01562 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NHAKPCLB_01563 4.58e-85 ywnA - - K - - - Transcriptional regulator
NHAKPCLB_01564 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHAKPCLB_01565 6.46e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NHAKPCLB_01566 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NHAKPCLB_01567 2.15e-19 csbD - - K - - - CsbD-like
NHAKPCLB_01568 3.22e-109 ywmF - - S - - - Peptidase M50
NHAKPCLB_01569 2.18e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_01570 3.1e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHAKPCLB_01571 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHAKPCLB_01573 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NHAKPCLB_01574 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NHAKPCLB_01575 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NHAKPCLB_01576 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHAKPCLB_01577 6.59e-172 ywmB - - S - - - TATA-box binding
NHAKPCLB_01578 4.54e-45 ywzB - - S - - - membrane
NHAKPCLB_01579 2.92e-113 ywmA - - - - - - -
NHAKPCLB_01580 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NHAKPCLB_01581 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHAKPCLB_01582 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHAKPCLB_01583 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHAKPCLB_01584 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHAKPCLB_01585 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHAKPCLB_01586 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHAKPCLB_01587 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NHAKPCLB_01588 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NHAKPCLB_01589 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHAKPCLB_01590 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHAKPCLB_01591 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
NHAKPCLB_01592 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NHAKPCLB_01593 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHAKPCLB_01594 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
NHAKPCLB_01595 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHAKPCLB_01596 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NHAKPCLB_01597 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NHAKPCLB_01598 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NHAKPCLB_01600 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHAKPCLB_01601 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHAKPCLB_01602 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_01603 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NHAKPCLB_01604 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NHAKPCLB_01605 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NHAKPCLB_01606 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NHAKPCLB_01607 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NHAKPCLB_01608 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHAKPCLB_01609 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NHAKPCLB_01610 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHAKPCLB_01612 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHAKPCLB_01613 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NHAKPCLB_01614 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NHAKPCLB_01615 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
NHAKPCLB_01616 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHAKPCLB_01617 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHAKPCLB_01618 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
NHAKPCLB_01619 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NHAKPCLB_01620 5.54e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NHAKPCLB_01621 1.4e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NHAKPCLB_01622 5.49e-124 ywjB - - H - - - RibD C-terminal domain
NHAKPCLB_01623 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NHAKPCLB_01624 9.8e-37 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NHAKPCLB_01625 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHAKPCLB_01626 8.39e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NHAKPCLB_01627 2.77e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NHAKPCLB_01628 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NHAKPCLB_01629 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHAKPCLB_01630 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NHAKPCLB_01631 1.84e-179 ywiC - - S - - - YwiC-like protein
NHAKPCLB_01632 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NHAKPCLB_01633 8.44e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NHAKPCLB_01634 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NHAKPCLB_01635 5.42e-95 ywiB - - S - - - protein conserved in bacteria
NHAKPCLB_01636 3.71e-12 - - - S - - - Bacteriocin subtilosin A
NHAKPCLB_01637 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
NHAKPCLB_01639 6.11e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NHAKPCLB_01640 1.09e-293 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
NHAKPCLB_01641 4.01e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
NHAKPCLB_01642 7.39e-312 - - - L - - - Peptidase, M16
NHAKPCLB_01644 1.18e-315 ywhL - - CO - - - amine dehydrogenase activity
NHAKPCLB_01645 4.48e-273 ywhK - - CO - - - amine dehydrogenase activity
NHAKPCLB_01646 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NHAKPCLB_01648 2.03e-84 - - - S - - - Aminoacyl-tRNA editing domain
NHAKPCLB_01649 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NHAKPCLB_01650 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NHAKPCLB_01651 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NHAKPCLB_01652 2.1e-64 - - - - - - - -
NHAKPCLB_01653 1.92e-123 ywhD - - S - - - YwhD family
NHAKPCLB_01654 3.29e-154 ywhC - - S - - - Peptidase family M50
NHAKPCLB_01655 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NHAKPCLB_01656 1.45e-93 ywhA - - K - - - Transcriptional regulator
NHAKPCLB_01657 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHAKPCLB_01659 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NHAKPCLB_01660 1.1e-103 yffB - - K - - - Transcriptional regulator
NHAKPCLB_01661 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
NHAKPCLB_01662 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NHAKPCLB_01663 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NHAKPCLB_01664 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NHAKPCLB_01665 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
NHAKPCLB_01666 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NHAKPCLB_01667 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_01668 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NHAKPCLB_01669 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NHAKPCLB_01670 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NHAKPCLB_01671 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NHAKPCLB_01672 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NHAKPCLB_01673 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NHAKPCLB_01674 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_01675 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NHAKPCLB_01676 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NHAKPCLB_01677 3.81e-275 ywfA - - EGP - - - -transporter
NHAKPCLB_01678 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NHAKPCLB_01679 0.0 rocB - - E - - - arginine degradation protein
NHAKPCLB_01680 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHAKPCLB_01681 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NHAKPCLB_01682 2.14e-100 - - - - - - - -
NHAKPCLB_01683 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NHAKPCLB_01684 1.92e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHAKPCLB_01685 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHAKPCLB_01686 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHAKPCLB_01687 5.73e-240 spsG - - M - - - Spore Coat
NHAKPCLB_01688 1.09e-167 spsF - - M ko:K07257 - ko00000 Spore Coat
NHAKPCLB_01689 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NHAKPCLB_01690 1.41e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NHAKPCLB_01691 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NHAKPCLB_01692 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NHAKPCLB_01693 7.76e-185 spsA - - M - - - Spore Coat
NHAKPCLB_01694 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NHAKPCLB_01695 1.59e-78 ywdK - - S - - - small membrane protein
NHAKPCLB_01696 3.75e-303 ywdJ - - F - - - Xanthine uracil
NHAKPCLB_01697 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
NHAKPCLB_01698 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NHAKPCLB_01699 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHAKPCLB_01700 5.46e-191 ywdF - - S - - - Glycosyltransferase like family 2
NHAKPCLB_01701 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NHAKPCLB_01702 6.19e-39 ywdA - - - - - - -
NHAKPCLB_01703 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NHAKPCLB_01704 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_01705 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
NHAKPCLB_01706 6.46e-112 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NHAKPCLB_01707 5e-63 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NHAKPCLB_01709 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NHAKPCLB_01710 2.83e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHAKPCLB_01711 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NHAKPCLB_01712 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NHAKPCLB_01713 3.69e-260 - - - S - - - Acetyltransferase
NHAKPCLB_01714 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NHAKPCLB_01715 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NHAKPCLB_01716 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NHAKPCLB_01717 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHAKPCLB_01718 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NHAKPCLB_01719 5.11e-49 ydaS - - S - - - membrane
NHAKPCLB_01720 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NHAKPCLB_01721 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHAKPCLB_01722 3.33e-77 gtcA - - S - - - GtrA-like protein
NHAKPCLB_01723 1.98e-157 ywcC - - K - - - transcriptional regulator
NHAKPCLB_01725 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
NHAKPCLB_01726 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHAKPCLB_01727 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NHAKPCLB_01728 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NHAKPCLB_01729 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NHAKPCLB_01730 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NHAKPCLB_01731 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHAKPCLB_01732 1.54e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHAKPCLB_01733 1.28e-201 ywbI - - K - - - Transcriptional regulator
NHAKPCLB_01734 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NHAKPCLB_01735 1.21e-143 ywbG - - M - - - effector of murein hydrolase
NHAKPCLB_01736 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
NHAKPCLB_01737 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NHAKPCLB_01738 1.9e-278 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NHAKPCLB_01739 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NHAKPCLB_01740 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
NHAKPCLB_01741 1.05e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHAKPCLB_01742 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NHAKPCLB_01743 2.67e-308 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_01744 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NHAKPCLB_01745 1.54e-215 gspA - - M - - - General stress
NHAKPCLB_01746 3.49e-158 ywaF - - S - - - Integral membrane protein
NHAKPCLB_01747 1.25e-114 ywaE - - K - - - Transcriptional regulator
NHAKPCLB_01748 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHAKPCLB_01749 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NHAKPCLB_01750 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NHAKPCLB_01764 4.3e-201 - - - S - - - damaged DNA binding
NHAKPCLB_01765 3.15e-36 - - - - - - - -
NHAKPCLB_01767 8.02e-30 - - - V - - - VanZ like family
NHAKPCLB_01772 1.4e-193 - - - - ko:K18640 - ko00000,ko04812 -
NHAKPCLB_01773 6.01e-61 - - - K - - - COG0457 FOG TPR repeat
NHAKPCLB_01775 0.000863 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHAKPCLB_01779 2.47e-36 - - - S - - - Domain of unknown function (DUF5052)
NHAKPCLB_01782 1.64e-278 - - - M - - - domain protein
NHAKPCLB_01786 1.43e-138 - - - NU ko:K02283 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
NHAKPCLB_01787 4.6e-99 - - - - - - - -
NHAKPCLB_01788 4.26e-66 - - - - - - - -
NHAKPCLB_01789 3.88e-34 - - - - - - - -
NHAKPCLB_01797 4.48e-214 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
NHAKPCLB_01798 4.33e-50 - - - S - - - domain, Protein
NHAKPCLB_01800 1.47e-47 - - - - - - - -
NHAKPCLB_01801 5.71e-216 - - - S - - - AAA-like domain
NHAKPCLB_01803 9.35e-69 yddH - - M - - - Lysozyme-like
NHAKPCLB_01807 1.86e-111 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
NHAKPCLB_01809 2.51e-49 - - - L - - - Protein of unknown function (DUF3991)
NHAKPCLB_01813 2.5e-06 rok - - S - - - Repressor of ComK
NHAKPCLB_01815 4.64e-65 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHAKPCLB_01818 2.28e-53 - - - L - - - Site-specific recombinase, phage integrase family
NHAKPCLB_01824 1.32e-151 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NHAKPCLB_01827 3.45e-48 nucH 3.1.31.1 - L ko:K01174 - ko00000,ko01000 COG1525 Micrococcal nuclease (thermonuclease) homologs
NHAKPCLB_01830 8.73e-109 - - - L - - - Domain of unknown function (DUF1738)
NHAKPCLB_01831 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NHAKPCLB_01832 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_01833 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NHAKPCLB_01834 2.43e-58 yjcN - - - - - - -
NHAKPCLB_01835 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NHAKPCLB_01836 2.49e-07 - - - - - - - -
NHAKPCLB_01837 2.28e-25 - - - - - - - -
NHAKPCLB_01838 1.92e-47 - - - - - - - -
NHAKPCLB_01842 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_01844 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
NHAKPCLB_01846 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NHAKPCLB_01848 5.36e-203 ybaS - - S - - - Na -dependent transporter
NHAKPCLB_01849 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
NHAKPCLB_01850 3.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_01851 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_01852 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NHAKPCLB_01853 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NHAKPCLB_01854 2.33e-302 ybbC - - S - - - protein conserved in bacteria
NHAKPCLB_01855 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NHAKPCLB_01856 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NHAKPCLB_01857 2.97e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_01858 2.4e-190 ybbH - - K - - - transcriptional
NHAKPCLB_01859 1.92e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHAKPCLB_01860 3.13e-114 ybbJ - - J - - - acetyltransferase
NHAKPCLB_01861 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
NHAKPCLB_01867 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_01868 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NHAKPCLB_01869 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHAKPCLB_01870 1.6e-287 ybbR - - S - - - protein conserved in bacteria
NHAKPCLB_01871 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHAKPCLB_01872 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHAKPCLB_01873 5.87e-54 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHAKPCLB_01874 9.34e-128 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHAKPCLB_01875 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NHAKPCLB_01876 1.29e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHAKPCLB_01877 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHAKPCLB_01878 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
NHAKPCLB_01879 9.45e-121 ybcF - - P - - - carbonic anhydrase
NHAKPCLB_01881 1.6e-63 - - - - - - - -
NHAKPCLB_01882 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
NHAKPCLB_01883 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NHAKPCLB_01884 2.78e-219 - - - T - - - His Kinase A (phospho-acceptor) domain
NHAKPCLB_01886 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NHAKPCLB_01887 1.49e-192 ybdN - - - - - - -
NHAKPCLB_01888 8.98e-274 ybdO - - S - - - Domain of unknown function (DUF4885)
NHAKPCLB_01889 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_01890 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NHAKPCLB_01891 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
NHAKPCLB_01892 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
NHAKPCLB_01893 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NHAKPCLB_01894 1.28e-37 ybyB - - - - - - -
NHAKPCLB_01895 0.0 ybeC - - E - - - amino acid
NHAKPCLB_01896 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NHAKPCLB_01897 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NHAKPCLB_01898 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
NHAKPCLB_01899 8.65e-202 ybfA - - K - - - FR47-like protein
NHAKPCLB_01900 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_01901 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_01904 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
NHAKPCLB_01905 1.06e-207 ybfH - - EG - - - EamA-like transporter family
NHAKPCLB_01906 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
NHAKPCLB_01907 3.63e-43 - - - K - - - sigma factor activity
NHAKPCLB_01908 2.73e-28 xhlB - - S - - - SPP1 phage holin
NHAKPCLB_01909 0.0 - - - - - - - -
NHAKPCLB_01910 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NHAKPCLB_01911 1.96e-141 - - - S - - - Phage tail protein
NHAKPCLB_01912 0.0 - - - S - - - peptidoglycan catabolic process
NHAKPCLB_01913 4.09e-16 - - - - - - - -
NHAKPCLB_01914 1.58e-36 - - - - - - - -
NHAKPCLB_01915 9.75e-79 - - - - - - - -
NHAKPCLB_01916 1.42e-40 - - - - - - - -
NHAKPCLB_01917 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHAKPCLB_01918 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
NHAKPCLB_01919 1.23e-39 - - - S - - - peptidoglycan catabolic process
NHAKPCLB_01920 8.02e-09 - - - S - - - peptidoglycan catabolic process
NHAKPCLB_01921 3.43e-227 - - - S - - - capsid protein
NHAKPCLB_01922 9.36e-135 - - - S - - - peptidase activity
NHAKPCLB_01923 4.77e-273 - - - S - - - Phage portal protein
NHAKPCLB_01924 2.58e-14 - - - - - - - -
NHAKPCLB_01925 1.37e-277 - - - S - - - Phage Terminase
NHAKPCLB_01926 1e-89 - - - S - - - Phage terminase, small subunit
NHAKPCLB_01927 2.63e-11 - - - - - - - -
NHAKPCLB_01928 5.52e-31 - - - M - - - ArpU family transcriptional regulator
NHAKPCLB_01933 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHAKPCLB_01934 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHAKPCLB_01935 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NHAKPCLB_01936 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NHAKPCLB_01937 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHAKPCLB_01938 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHAKPCLB_01939 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NHAKPCLB_01940 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NHAKPCLB_01941 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NHAKPCLB_01942 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NHAKPCLB_01943 1.82e-276 pbpX - - V - - - Beta-lactamase
NHAKPCLB_01944 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHAKPCLB_01945 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NHAKPCLB_01946 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHAKPCLB_01947 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NHAKPCLB_01948 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
NHAKPCLB_01949 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
NHAKPCLB_01950 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NHAKPCLB_01951 2.37e-309 ymfH - - S - - - zinc protease
NHAKPCLB_01952 9.47e-299 albE - - S - - - Peptidase M16
NHAKPCLB_01953 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_01954 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_01955 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NHAKPCLB_01956 4.94e-44 - - - S - - - YlzJ-like protein
NHAKPCLB_01957 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NHAKPCLB_01958 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHAKPCLB_01959 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHAKPCLB_01960 2.83e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NHAKPCLB_01961 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHAKPCLB_01962 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NHAKPCLB_01963 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NHAKPCLB_01964 1.53e-56 ymxH - - S - - - YlmC YmxH family
NHAKPCLB_01965 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
NHAKPCLB_01966 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NHAKPCLB_01967 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHAKPCLB_01968 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHAKPCLB_01969 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NHAKPCLB_01970 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHAKPCLB_01971 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHAKPCLB_01972 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NHAKPCLB_01973 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHAKPCLB_01974 6.16e-63 ylxQ - - J - - - ribosomal protein
NHAKPCLB_01975 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NHAKPCLB_01976 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NHAKPCLB_01977 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NHAKPCLB_01978 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHAKPCLB_01979 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHAKPCLB_01980 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NHAKPCLB_01981 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NHAKPCLB_01982 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NHAKPCLB_01983 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHAKPCLB_01984 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHAKPCLB_01985 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NHAKPCLB_01986 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHAKPCLB_01987 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NHAKPCLB_01988 2.81e-100 ylxL - - - - - - -
NHAKPCLB_01989 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_01990 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NHAKPCLB_01991 4.54e-60 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NHAKPCLB_01992 5.88e-54 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NHAKPCLB_01993 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NHAKPCLB_01994 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NHAKPCLB_01995 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NHAKPCLB_01996 1.28e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NHAKPCLB_01997 1.89e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NHAKPCLB_01998 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHAKPCLB_01999 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHAKPCLB_02000 8.38e-148 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NHAKPCLB_02001 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NHAKPCLB_02002 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NHAKPCLB_02003 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NHAKPCLB_02004 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NHAKPCLB_02005 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NHAKPCLB_02006 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHAKPCLB_02007 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NHAKPCLB_02008 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NHAKPCLB_02009 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NHAKPCLB_02010 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NHAKPCLB_02011 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
NHAKPCLB_02012 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NHAKPCLB_02013 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NHAKPCLB_02014 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NHAKPCLB_02015 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHAKPCLB_02016 7.5e-188 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NHAKPCLB_02017 1.07e-95 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NHAKPCLB_02018 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NHAKPCLB_02019 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NHAKPCLB_02020 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NHAKPCLB_02021 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHAKPCLB_02022 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHAKPCLB_02023 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHAKPCLB_02024 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NHAKPCLB_02025 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHAKPCLB_02026 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHAKPCLB_02027 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NHAKPCLB_02028 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHAKPCLB_02029 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHAKPCLB_02030 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NHAKPCLB_02031 0.0 ylqG - - - - - - -
NHAKPCLB_02032 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHAKPCLB_02033 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHAKPCLB_02034 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHAKPCLB_02035 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NHAKPCLB_02036 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHAKPCLB_02037 3.41e-80 ylqD - - S - - - YlqD protein
NHAKPCLB_02038 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NHAKPCLB_02039 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NHAKPCLB_02040 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHAKPCLB_02041 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHAKPCLB_02042 1.67e-114 - - - - - - - -
NHAKPCLB_02043 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHAKPCLB_02044 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NHAKPCLB_02045 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHAKPCLB_02046 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHAKPCLB_02047 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NHAKPCLB_02048 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NHAKPCLB_02049 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHAKPCLB_02050 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NHAKPCLB_02051 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHAKPCLB_02052 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NHAKPCLB_02053 5.89e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NHAKPCLB_02054 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NHAKPCLB_02055 3.65e-78 yloU - - S - - - protein conserved in bacteria
NHAKPCLB_02056 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NHAKPCLB_02057 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NHAKPCLB_02058 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NHAKPCLB_02059 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHAKPCLB_02060 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NHAKPCLB_02061 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NHAKPCLB_02062 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHAKPCLB_02063 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHAKPCLB_02064 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHAKPCLB_02065 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHAKPCLB_02066 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHAKPCLB_02067 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHAKPCLB_02068 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHAKPCLB_02069 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NHAKPCLB_02070 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NHAKPCLB_02071 8.41e-202 yloC - - S - - - stress-induced protein
NHAKPCLB_02072 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NHAKPCLB_02073 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NHAKPCLB_02074 3.78e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NHAKPCLB_02075 8.38e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NHAKPCLB_02076 1.45e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NHAKPCLB_02077 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NHAKPCLB_02078 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NHAKPCLB_02079 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NHAKPCLB_02080 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NHAKPCLB_02081 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHAKPCLB_02082 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHAKPCLB_02083 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHAKPCLB_02084 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHAKPCLB_02085 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NHAKPCLB_02086 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NHAKPCLB_02087 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHAKPCLB_02088 5.99e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NHAKPCLB_02089 8.02e-291 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NHAKPCLB_02090 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHAKPCLB_02091 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NHAKPCLB_02092 1.89e-98 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHAKPCLB_02093 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NHAKPCLB_02094 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHAKPCLB_02095 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NHAKPCLB_02096 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
NHAKPCLB_02097 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NHAKPCLB_02098 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHAKPCLB_02099 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHAKPCLB_02100 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NHAKPCLB_02101 3.58e-51 ylmC - - S - - - sporulation protein
NHAKPCLB_02102 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NHAKPCLB_02103 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NHAKPCLB_02104 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_02105 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_02106 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NHAKPCLB_02108 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NHAKPCLB_02109 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHAKPCLB_02110 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHAKPCLB_02111 5.37e-76 sbp - - S - - - small basic protein
NHAKPCLB_02112 8.67e-132 ylxX - - S - - - protein conserved in bacteria
NHAKPCLB_02113 3.45e-146 ylxW - - S - - - protein conserved in bacteria
NHAKPCLB_02114 1.37e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHAKPCLB_02115 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NHAKPCLB_02116 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHAKPCLB_02117 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NHAKPCLB_02118 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHAKPCLB_02119 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHAKPCLB_02120 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHAKPCLB_02121 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NHAKPCLB_02122 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHAKPCLB_02123 3.42e-68 ftsL - - D - - - Essential cell division protein
NHAKPCLB_02124 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHAKPCLB_02125 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NHAKPCLB_02126 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NHAKPCLB_02127 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHAKPCLB_02128 1.33e-115 ylbP - - K - - - n-acetyltransferase
NHAKPCLB_02129 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NHAKPCLB_02130 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NHAKPCLB_02131 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NHAKPCLB_02133 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
NHAKPCLB_02134 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NHAKPCLB_02135 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NHAKPCLB_02136 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NHAKPCLB_02137 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHAKPCLB_02138 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NHAKPCLB_02139 4.36e-52 ylbG - - S - - - UPF0298 protein
NHAKPCLB_02140 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
NHAKPCLB_02141 1.73e-48 ylbE - - S - - - YlbE-like protein
NHAKPCLB_02142 3.24e-89 ylbD - - S - - - Putative coat protein
NHAKPCLB_02143 2.18e-256 ylbC - - S - - - protein with SCP PR1 domains
NHAKPCLB_02144 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
NHAKPCLB_02145 1.88e-80 ylbA - - S - - - YugN-like family
NHAKPCLB_02146 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NHAKPCLB_02147 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NHAKPCLB_02148 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NHAKPCLB_02149 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHAKPCLB_02150 2.28e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NHAKPCLB_02151 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHAKPCLB_02152 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NHAKPCLB_02153 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NHAKPCLB_02154 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NHAKPCLB_02155 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
NHAKPCLB_02156 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NHAKPCLB_02157 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NHAKPCLB_02158 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NHAKPCLB_02159 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHAKPCLB_02160 8.92e-44 ylaI - - S - - - protein conserved in bacteria
NHAKPCLB_02161 4.4e-63 ylaH - - S - - - YlaH-like protein
NHAKPCLB_02162 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NHAKPCLB_02163 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
NHAKPCLB_02164 1.74e-57 ylaE - - - - - - -
NHAKPCLB_02166 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_02167 1.44e-56 ylaB - - - - - - -
NHAKPCLB_02168 0.0 ylaA - - - - - - -
NHAKPCLB_02169 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NHAKPCLB_02170 2.57e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NHAKPCLB_02171 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
NHAKPCLB_02172 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NHAKPCLB_02173 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_02174 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHAKPCLB_02175 1.05e-22 - - - - - - - -
NHAKPCLB_02176 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NHAKPCLB_02177 3.71e-110 ykyB - - S - - - YkyB-like protein
NHAKPCLB_02178 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_02179 5.84e-115 ykuD - - S - - - protein conserved in bacteria
NHAKPCLB_02180 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NHAKPCLB_02181 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_02182 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
NHAKPCLB_02183 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
NHAKPCLB_02184 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
NHAKPCLB_02185 7.83e-38 ykzF - - S - - - Antirepressor AbbA
NHAKPCLB_02186 6.01e-99 ykuL - - S - - - CBS domain
NHAKPCLB_02187 7.61e-215 ccpC - - K - - - Transcriptional regulator
NHAKPCLB_02188 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
NHAKPCLB_02189 1.74e-222 ykuO - - - - - - -
NHAKPCLB_02190 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NHAKPCLB_02191 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHAKPCLB_02192 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHAKPCLB_02193 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
NHAKPCLB_02194 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NHAKPCLB_02195 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
NHAKPCLB_02196 4.23e-104 ykuV - - CO - - - thiol-disulfide
NHAKPCLB_02197 4.71e-122 rok - - K - - - Repressor of ComK
NHAKPCLB_02198 6.44e-139 yodC - - C - - - nitroreductase
NHAKPCLB_02199 2.63e-73 yodB - - K - - - transcriptional
NHAKPCLB_02200 2.3e-83 iolK - - S - - - tautomerase
NHAKPCLB_02201 7.01e-96 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NHAKPCLB_02202 1.26e-168 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NHAKPCLB_02203 5.59e-14 - - - - - - - -
NHAKPCLB_02204 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NHAKPCLB_02205 1.64e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NHAKPCLB_02206 1.85e-58 - - - - - - - -
NHAKPCLB_02207 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NHAKPCLB_02208 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NHAKPCLB_02209 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHAKPCLB_02210 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NHAKPCLB_02212 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHAKPCLB_02213 3.79e-292 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NHAKPCLB_02214 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NHAKPCLB_02215 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHAKPCLB_02216 8.98e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NHAKPCLB_02217 0.0 yojO - - P - - - Von Willebrand factor
NHAKPCLB_02218 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NHAKPCLB_02219 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NHAKPCLB_02220 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
NHAKPCLB_02221 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHAKPCLB_02222 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NHAKPCLB_02223 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NHAKPCLB_02224 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NHAKPCLB_02225 1.91e-42 yozC - - - - - - -
NHAKPCLB_02226 2.17e-74 yozO - - S - - - Bacterial PH domain
NHAKPCLB_02227 1.83e-49 yocN - - - - - - -
NHAKPCLB_02228 2.94e-55 yozN - - - - - - -
NHAKPCLB_02229 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHAKPCLB_02230 3.93e-41 - - - - - - - -
NHAKPCLB_02231 4.29e-70 yocL - - - - - - -
NHAKPCLB_02232 2.87e-107 yocK - - T - - - general stress protein
NHAKPCLB_02233 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHAKPCLB_02234 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHAKPCLB_02235 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
NHAKPCLB_02237 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_02238 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_02239 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NHAKPCLB_02240 3.72e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NHAKPCLB_02241 1.08e-121 yocC - - - - - - -
NHAKPCLB_02242 8.68e-67 - - - - - - - -
NHAKPCLB_02243 9.86e-88 - - - - - - - -
NHAKPCLB_02244 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
NHAKPCLB_02245 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHAKPCLB_02246 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NHAKPCLB_02247 2.58e-121 yobW - - - - - - -
NHAKPCLB_02248 2.76e-220 yobV - - K - - - WYL domain
NHAKPCLB_02249 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
NHAKPCLB_02250 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NHAKPCLB_02251 7.27e-126 yobS - - K - - - Transcriptional regulator
NHAKPCLB_02252 1.98e-178 - - - J - - - FR47-like protein
NHAKPCLB_02253 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NHAKPCLB_02254 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NHAKPCLB_02255 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
NHAKPCLB_02256 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
NHAKPCLB_02257 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHAKPCLB_02258 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NHAKPCLB_02259 5.49e-102 - - - S - - - SMI1-KNR4 cell-wall
NHAKPCLB_02260 5.44e-124 yokK - - S - - - SMI1 / KNR4 family
NHAKPCLB_02261 2.06e-125 - - - J - - - Acetyltransferase (GNAT) domain
NHAKPCLB_02264 2.34e-14 - - - S - - - YolD-like protein
NHAKPCLB_02265 4.84e-85 - - - S - - - damaged DNA binding
NHAKPCLB_02266 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHAKPCLB_02267 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHAKPCLB_02269 4.82e-294 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NHAKPCLB_02270 1.49e-207 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
NHAKPCLB_02272 7.7e-248 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
NHAKPCLB_02273 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NHAKPCLB_02274 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_02275 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_02276 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NHAKPCLB_02277 2.19e-153 yxaC - - M - - - effector of murein hydrolase
NHAKPCLB_02278 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
NHAKPCLB_02279 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NHAKPCLB_02280 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
NHAKPCLB_02281 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NHAKPCLB_02282 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NHAKPCLB_02283 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHAKPCLB_02284 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NHAKPCLB_02285 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NHAKPCLB_02286 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHAKPCLB_02287 1.98e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_02288 4.79e-160 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_02289 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_02290 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_02291 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NHAKPCLB_02292 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
NHAKPCLB_02293 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
NHAKPCLB_02294 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NHAKPCLB_02295 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NHAKPCLB_02296 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NHAKPCLB_02297 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NHAKPCLB_02298 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NHAKPCLB_02299 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHAKPCLB_02300 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NHAKPCLB_02301 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NHAKPCLB_02302 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NHAKPCLB_02303 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHAKPCLB_02304 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHAKPCLB_02305 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NHAKPCLB_02306 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NHAKPCLB_02307 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHAKPCLB_02308 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHAKPCLB_02309 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NHAKPCLB_02310 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NHAKPCLB_02311 1.08e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHAKPCLB_02312 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NHAKPCLB_02313 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHAKPCLB_02314 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHAKPCLB_02315 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHAKPCLB_02316 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHAKPCLB_02317 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NHAKPCLB_02318 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHAKPCLB_02319 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHAKPCLB_02320 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NHAKPCLB_02321 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHAKPCLB_02322 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHAKPCLB_02323 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHAKPCLB_02324 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHAKPCLB_02325 7.13e-228 ybaC - - S - - - Alpha/beta hydrolase family
NHAKPCLB_02326 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NHAKPCLB_02327 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHAKPCLB_02328 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NHAKPCLB_02329 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHAKPCLB_02330 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHAKPCLB_02331 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHAKPCLB_02332 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHAKPCLB_02333 6.89e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHAKPCLB_02334 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHAKPCLB_02335 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NHAKPCLB_02336 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHAKPCLB_02337 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHAKPCLB_02338 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHAKPCLB_02339 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHAKPCLB_02340 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHAKPCLB_02341 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHAKPCLB_02342 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHAKPCLB_02343 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHAKPCLB_02344 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHAKPCLB_02345 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NHAKPCLB_02346 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NHAKPCLB_02347 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHAKPCLB_02348 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHAKPCLB_02349 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NHAKPCLB_02350 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHAKPCLB_02351 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NHAKPCLB_02352 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHAKPCLB_02353 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHAKPCLB_02354 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHAKPCLB_02355 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NHAKPCLB_02356 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHAKPCLB_02357 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHAKPCLB_02358 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHAKPCLB_02359 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHAKPCLB_02360 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHAKPCLB_02361 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NHAKPCLB_02362 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
NHAKPCLB_02363 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
NHAKPCLB_02364 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_02365 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NHAKPCLB_02366 1.04e-122 gerD - - - ko:K06294 - ko00000 -
NHAKPCLB_02367 1.71e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NHAKPCLB_02368 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
NHAKPCLB_02369 2.51e-39 yjzC - - S - - - YjzC-like protein
NHAKPCLB_02370 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
NHAKPCLB_02371 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
NHAKPCLB_02372 5.2e-132 yjaV - - - - - - -
NHAKPCLB_02373 3.04e-233 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NHAKPCLB_02374 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NHAKPCLB_02375 3.48e-33 yjzB - - - - - - -
NHAKPCLB_02376 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHAKPCLB_02377 5.08e-301 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHAKPCLB_02378 3.86e-192 yjaZ - - O - - - Zn-dependent protease
NHAKPCLB_02379 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_02380 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_02381 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NHAKPCLB_02382 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_02383 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_02384 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
NHAKPCLB_02385 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NHAKPCLB_02386 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NHAKPCLB_02387 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_02388 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHAKPCLB_02389 1.12e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_02390 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NHAKPCLB_02391 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
NHAKPCLB_02392 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_02393 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHAKPCLB_02394 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
NHAKPCLB_02395 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHAKPCLB_02396 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
NHAKPCLB_02397 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NHAKPCLB_02398 2.68e-28 - - - - - - - -
NHAKPCLB_02399 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NHAKPCLB_02400 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NHAKPCLB_02401 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHAKPCLB_02402 7.02e-128 yjbK - - S - - - protein conserved in bacteria
NHAKPCLB_02403 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
NHAKPCLB_02404 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NHAKPCLB_02405 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHAKPCLB_02406 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NHAKPCLB_02407 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NHAKPCLB_02408 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHAKPCLB_02409 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHAKPCLB_02410 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NHAKPCLB_02411 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NHAKPCLB_02412 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
NHAKPCLB_02413 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NHAKPCLB_02414 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHAKPCLB_02415 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NHAKPCLB_02416 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NHAKPCLB_02417 2.09e-103 yjbX - - S - - - Spore coat protein
NHAKPCLB_02418 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NHAKPCLB_02419 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NHAKPCLB_02420 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NHAKPCLB_02421 1.51e-18 cotW - - - ko:K06341 - ko00000 -
NHAKPCLB_02423 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
NHAKPCLB_02426 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
NHAKPCLB_02427 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHAKPCLB_02428 6.31e-51 - - - - - - - -
NHAKPCLB_02429 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_02430 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NHAKPCLB_02431 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NHAKPCLB_02432 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NHAKPCLB_02433 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NHAKPCLB_02434 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NHAKPCLB_02435 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
NHAKPCLB_02437 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
NHAKPCLB_02438 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
NHAKPCLB_02439 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
NHAKPCLB_02441 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
NHAKPCLB_02442 5.33e-85 - - - - - - - -
NHAKPCLB_02443 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
NHAKPCLB_02444 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NHAKPCLB_02445 7.6e-12 - - - S - - - Helix-turn-helix domain
NHAKPCLB_02446 2.09e-103 - - - - - - - -
NHAKPCLB_02447 7.47e-233 yaaC - - S - - - YaaC-like Protein
NHAKPCLB_02448 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHAKPCLB_02449 1.24e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHAKPCLB_02450 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHAKPCLB_02451 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHAKPCLB_02452 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHAKPCLB_02454 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NHAKPCLB_02455 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NHAKPCLB_02456 1.48e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NHAKPCLB_02457 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NHAKPCLB_02458 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHAKPCLB_02459 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHAKPCLB_02460 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHAKPCLB_02461 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHAKPCLB_02462 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
NHAKPCLB_02463 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NHAKPCLB_02464 2.23e-90 - - - S - - - Regulatory protein YrvL
NHAKPCLB_02465 9.3e-126 ymcC - - S - - - Membrane
NHAKPCLB_02466 1.02e-134 pksA - - K - - - Transcriptional regulator
NHAKPCLB_02467 8.03e-81 ymzB - - - - - - -
NHAKPCLB_02468 1.04e-204 - - - S - - - Metallo-beta-lactamase superfamily
NHAKPCLB_02469 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NHAKPCLB_02471 8e-163 ymaC - - S - - - Replication protein
NHAKPCLB_02472 6.98e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NHAKPCLB_02473 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
NHAKPCLB_02474 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NHAKPCLB_02476 3.13e-75 ymaF - - S - - - YmaF family
NHAKPCLB_02477 5.61e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHAKPCLB_02478 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NHAKPCLB_02479 1.63e-31 - - - - - - - -
NHAKPCLB_02480 1.2e-30 ymzA - - - - - - -
NHAKPCLB_02481 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NHAKPCLB_02482 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHAKPCLB_02483 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHAKPCLB_02484 2.24e-141 - - - - - - - -
NHAKPCLB_02485 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_02486 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NHAKPCLB_02487 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHAKPCLB_02488 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NHAKPCLB_02489 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NHAKPCLB_02490 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NHAKPCLB_02491 4.35e-171 - - - L - - - Belongs to the 'phage' integrase family
NHAKPCLB_02492 1.4e-59 - - - CE - - - IrrE N-terminal-like domain
NHAKPCLB_02493 3.93e-09 - - - K - - - Helix-turn-helix
NHAKPCLB_02495 7.74e-65 - - - S - - - Phage antirepressor protein KilAC domain
NHAKPCLB_02496 4.75e-28 - - - - - - - -
NHAKPCLB_02498 3.42e-26 - - - S - - - Uncharacterized protein YqaH
NHAKPCLB_02500 5.36e-120 - - - S - - - DNA protection
NHAKPCLB_02501 6.48e-216 - - - S - - - AAA domain
NHAKPCLB_02502 1.15e-07 - - - - - - - -
NHAKPCLB_02503 3.5e-97 - - - S - - - Protein of unknown function (DUF669)
NHAKPCLB_02504 0.0 - - - S - - - hydrolase activity
NHAKPCLB_02505 3.9e-85 - - - - - - - -
NHAKPCLB_02506 3.14e-121 - - - S - - - nuclease activity
NHAKPCLB_02507 1.06e-106 - - - - - - - -
NHAKPCLB_02509 2.62e-78 - - - - - - - -
NHAKPCLB_02513 1.34e-77 - - - L - - - Terminase, small subunit
NHAKPCLB_02514 0.0 terL - - S - - - Terminase
NHAKPCLB_02516 3.12e-215 - - - S - - - portal protein
NHAKPCLB_02517 3.96e-94 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NHAKPCLB_02518 1.64e-161 - - - S - - - capsid protein
NHAKPCLB_02519 5.45e-13 - - - - - - - -
NHAKPCLB_02521 8.17e-38 - - - S - - - Phage head-tail joining protein
NHAKPCLB_02522 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NHAKPCLB_02524 1.46e-33 - - - - - - - -
NHAKPCLB_02527 0.0 - - - D - - - Phage tail tape measure protein
NHAKPCLB_02529 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NHAKPCLB_02530 1.93e-122 - - GH19 M ko:K03791 - ko00000 Lysin motif
NHAKPCLB_02531 2.61e-73 - - - - - - - -
NHAKPCLB_02532 4.6e-271 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHAKPCLB_02533 1.69e-228 mpr - - M - - - Belongs to the peptidase S1B family
NHAKPCLB_02535 1.31e-212 - - - S - - - Alpha/beta hydrolase family
NHAKPCLB_02536 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHAKPCLB_02537 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
NHAKPCLB_02538 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NHAKPCLB_02539 2.25e-59 ybfN - - - - - - -
NHAKPCLB_02540 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
NHAKPCLB_02541 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_02542 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NHAKPCLB_02543 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHAKPCLB_02544 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_02545 1.01e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHAKPCLB_02546 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NHAKPCLB_02548 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NHAKPCLB_02549 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NHAKPCLB_02550 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NHAKPCLB_02551 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NHAKPCLB_02552 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NHAKPCLB_02553 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NHAKPCLB_02554 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_02555 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NHAKPCLB_02556 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
NHAKPCLB_02557 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHAKPCLB_02558 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_02559 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NHAKPCLB_02560 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
NHAKPCLB_02561 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NHAKPCLB_02562 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NHAKPCLB_02563 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NHAKPCLB_02564 4.05e-215 eamA1 - - EG - - - spore germination
NHAKPCLB_02565 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_02566 4.37e-214 ycbM - - T - - - Histidine kinase
NHAKPCLB_02567 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_02568 1.73e-149 - - - S - - - ABC-2 family transporter protein
NHAKPCLB_02569 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
NHAKPCLB_02570 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NHAKPCLB_02571 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
NHAKPCLB_02572 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NHAKPCLB_02573 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHAKPCLB_02574 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHAKPCLB_02575 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHAKPCLB_02576 4.66e-257 ycbU - - E - - - Selenocysteine lyase
NHAKPCLB_02577 4.75e-307 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NHAKPCLB_02578 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NHAKPCLB_02579 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHAKPCLB_02580 5.69e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHAKPCLB_02581 4.32e-78 - - - S - - - RDD family
NHAKPCLB_02582 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
NHAKPCLB_02583 4.03e-156 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHAKPCLB_02584 1.77e-43 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NHAKPCLB_02585 1.62e-161 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NHAKPCLB_02586 1.42e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NHAKPCLB_02587 2.86e-77 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NHAKPCLB_02588 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_02589 3.94e-221 yccK - - C - - - Aldo keto reductase
NHAKPCLB_02590 3.53e-226 ycdA - - S - - - Domain of unknown function (DUF5105)
NHAKPCLB_02591 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_02592 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_02593 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NHAKPCLB_02594 4.37e-182 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_02595 2.93e-45 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_02596 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NHAKPCLB_02597 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NHAKPCLB_02598 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NHAKPCLB_02599 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHAKPCLB_02600 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHAKPCLB_02601 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHAKPCLB_02602 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHAKPCLB_02603 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NHAKPCLB_02604 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NHAKPCLB_02605 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NHAKPCLB_02606 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NHAKPCLB_02607 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NHAKPCLB_02608 2.96e-245 yceH - - P - - - Belongs to the TelA family
NHAKPCLB_02609 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
NHAKPCLB_02610 5.46e-74 ygzB - - S - - - UPF0295 protein
NHAKPCLB_02611 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NHAKPCLB_02612 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NHAKPCLB_02613 1.89e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NHAKPCLB_02614 1.08e-237 ygaE - - S - - - Membrane
NHAKPCLB_02615 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NHAKPCLB_02616 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NHAKPCLB_02617 2.01e-49 ygaB - - S - - - YgaB-like protein
NHAKPCLB_02618 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NHAKPCLB_02619 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_02620 1.73e-48 yfhS - - - - - - -
NHAKPCLB_02621 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NHAKPCLB_02622 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NHAKPCLB_02623 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NHAKPCLB_02624 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NHAKPCLB_02625 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
NHAKPCLB_02626 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
NHAKPCLB_02627 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
NHAKPCLB_02628 8.95e-60 yfhJ - - S - - - WVELL protein
NHAKPCLB_02629 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
NHAKPCLB_02630 2.45e-268 yfhI - - EGP - - - -transporter
NHAKPCLB_02632 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
NHAKPCLB_02633 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NHAKPCLB_02634 1.88e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NHAKPCLB_02636 3.61e-34 yfhD - - S - - - YfhD-like protein
NHAKPCLB_02637 4.76e-137 yfhC - - C - - - nitroreductase
NHAKPCLB_02638 3.1e-214 yfhB - - S - - - PhzF family
NHAKPCLB_02639 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_02640 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHAKPCLB_02641 3.15e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NHAKPCLB_02642 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHAKPCLB_02643 2.11e-103 yfiV - - K - - - transcriptional
NHAKPCLB_02644 7.36e-215 yfiU - - EGP - - - the major facilitator superfamily
NHAKPCLB_02645 1.74e-131 yfiU - - EGP - - - the major facilitator superfamily
NHAKPCLB_02646 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NHAKPCLB_02647 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
NHAKPCLB_02648 1.57e-136 yfiR - - K - - - Transcriptional regulator
NHAKPCLB_02649 6.57e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NHAKPCLB_02650 5.67e-121 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHAKPCLB_02651 1.38e-121 padR - - K - - - transcriptional
NHAKPCLB_02652 6.08e-256 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NHAKPCLB_02653 1.15e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_02654 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_02655 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NHAKPCLB_02656 1.7e-272 baeS - - T - - - Histidine kinase
NHAKPCLB_02658 4.36e-249 - - - S - - - Oxidoreductase
NHAKPCLB_02659 2.46e-32 - - - S - - - Oxidoreductase
NHAKPCLB_02660 5.47e-234 - - - G - - - Xylose isomerase
NHAKPCLB_02661 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_02662 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
NHAKPCLB_02663 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NHAKPCLB_02664 4.74e-83 yfiD3 - - S - - - DoxX
NHAKPCLB_02665 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_02666 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NHAKPCLB_02667 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
NHAKPCLB_02668 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_02669 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NHAKPCLB_02670 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHAKPCLB_02671 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
NHAKPCLB_02672 1.94e-270 yfjB - - - - - - -
NHAKPCLB_02673 1.02e-184 yfjC - - - - - - -
NHAKPCLB_02674 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
NHAKPCLB_02675 1e-105 - - - S - - - Family of unknown function (DUF5381)
NHAKPCLB_02676 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
NHAKPCLB_02677 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NHAKPCLB_02678 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NHAKPCLB_02679 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHAKPCLB_02680 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHAKPCLB_02681 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHAKPCLB_02682 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHAKPCLB_02684 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
NHAKPCLB_02685 7.83e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHAKPCLB_02686 3.04e-59 - - - S - - - YfzA-like protein
NHAKPCLB_02687 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHAKPCLB_02688 5.57e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHAKPCLB_02689 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NHAKPCLB_02690 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHAKPCLB_02691 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NHAKPCLB_02692 3.26e-36 yfjT - - - - - - -
NHAKPCLB_02693 1.76e-283 yfkA - - S - - - YfkB-like domain
NHAKPCLB_02694 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
NHAKPCLB_02695 3.69e-189 yfkD - - S - - - YfkD-like protein
NHAKPCLB_02696 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NHAKPCLB_02697 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_02698 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NHAKPCLB_02699 1.03e-66 yfkI - - S - - - gas vesicle protein
NHAKPCLB_02700 5.04e-109 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHAKPCLB_02701 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
NHAKPCLB_02702 5.94e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_02703 1.24e-299 yoaB - - EGP - - - the major facilitator superfamily
NHAKPCLB_02704 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_02705 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NHAKPCLB_02706 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_02707 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NHAKPCLB_02708 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHAKPCLB_02709 7.05e-172 yoxB - - - - - - -
NHAKPCLB_02710 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
NHAKPCLB_02711 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_02712 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NHAKPCLB_02713 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHAKPCLB_02714 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHAKPCLB_02715 5.87e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHAKPCLB_02716 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_02717 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NHAKPCLB_02718 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NHAKPCLB_02719 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NHAKPCLB_02720 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_02721 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NHAKPCLB_02722 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
NHAKPCLB_02723 1.14e-124 - - - L - - - Integrase
NHAKPCLB_02725 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NHAKPCLB_02726 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHAKPCLB_02727 1.81e-41 yazB - - K - - - transcriptional
NHAKPCLB_02728 7.57e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHAKPCLB_02729 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHAKPCLB_02730 3.19e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHAKPCLB_02731 1.32e-215 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NHAKPCLB_02732 4.92e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NHAKPCLB_02733 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHAKPCLB_02734 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NHAKPCLB_02735 4.17e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NHAKPCLB_02736 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHAKPCLB_02737 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NHAKPCLB_02738 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHAKPCLB_02739 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NHAKPCLB_02740 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHAKPCLB_02741 3.83e-233 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NHAKPCLB_02742 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NHAKPCLB_02743 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NHAKPCLB_02746 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NHAKPCLB_02747 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NHAKPCLB_02748 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
NHAKPCLB_02749 1.91e-66 yabP - - S - - - Sporulation protein YabP
NHAKPCLB_02750 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHAKPCLB_02751 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NHAKPCLB_02752 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_02753 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NHAKPCLB_02754 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHAKPCLB_02755 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
NHAKPCLB_02756 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHAKPCLB_02757 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHAKPCLB_02758 3.51e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHAKPCLB_02759 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHAKPCLB_02760 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NHAKPCLB_02761 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NHAKPCLB_02762 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NHAKPCLB_02763 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHAKPCLB_02764 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
NHAKPCLB_02765 5.32e-53 veg - - S - - - protein conserved in bacteria
NHAKPCLB_02766 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
NHAKPCLB_02767 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHAKPCLB_02768 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHAKPCLB_02769 1.91e-283 yabE - - T - - - protein conserved in bacteria
NHAKPCLB_02770 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NHAKPCLB_02771 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHAKPCLB_02772 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NHAKPCLB_02773 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHAKPCLB_02774 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NHAKPCLB_02775 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NHAKPCLB_02776 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NHAKPCLB_02777 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NHAKPCLB_02778 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NHAKPCLB_02779 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NHAKPCLB_02780 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
NHAKPCLB_02781 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHAKPCLB_02782 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NHAKPCLB_02783 1.19e-258 yaaN - - P - - - Belongs to the TelA family
NHAKPCLB_02784 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NHAKPCLB_02785 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NHAKPCLB_02786 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NHAKPCLB_02789 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NHAKPCLB_02790 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NHAKPCLB_02791 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
NHAKPCLB_02792 2.52e-196 yndG - - S - - - DoxX-like family
NHAKPCLB_02793 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
NHAKPCLB_02794 0.0 yndJ - - S - - - YndJ-like protein
NHAKPCLB_02797 1.09e-173 yndL - - S - - - Replication protein
NHAKPCLB_02798 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
NHAKPCLB_02799 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NHAKPCLB_02800 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHAKPCLB_02801 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NHAKPCLB_02802 5.4e-143 yneB - - L - - - resolvase
NHAKPCLB_02803 1.15e-43 ynzC - - S - - - UPF0291 protein
NHAKPCLB_02804 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHAKPCLB_02805 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NHAKPCLB_02806 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NHAKPCLB_02807 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
NHAKPCLB_02808 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NHAKPCLB_02809 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NHAKPCLB_02810 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NHAKPCLB_02811 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
NHAKPCLB_02812 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
NHAKPCLB_02813 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NHAKPCLB_02814 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NHAKPCLB_02815 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHAKPCLB_02816 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHAKPCLB_02817 9.26e-10 - - - S - - - Fur-regulated basic protein B
NHAKPCLB_02819 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NHAKPCLB_02820 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NHAKPCLB_02821 3.3e-71 yneQ - - - - - - -
NHAKPCLB_02822 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
NHAKPCLB_02823 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHAKPCLB_02824 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NHAKPCLB_02825 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHAKPCLB_02826 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHAKPCLB_02827 1.82e-18 - - - - - - - -
NHAKPCLB_02828 8.74e-75 ynfC - - - - - - -
NHAKPCLB_02829 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NHAKPCLB_02830 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NHAKPCLB_02832 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NHAKPCLB_02833 3.29e-308 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_02834 5.64e-35 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_02835 1.72e-103 yngA - - S - - - membrane
NHAKPCLB_02836 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NHAKPCLB_02837 2.01e-134 yngC - - S - - - membrane-associated protein
NHAKPCLB_02838 1.23e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
NHAKPCLB_02839 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHAKPCLB_02840 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NHAKPCLB_02841 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NHAKPCLB_02842 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NHAKPCLB_02843 2.81e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NHAKPCLB_02844 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHAKPCLB_02845 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NHAKPCLB_02846 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NHAKPCLB_02847 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
NHAKPCLB_02848 8.25e-199 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NHAKPCLB_02849 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NHAKPCLB_02850 8.82e-37 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NHAKPCLB_02851 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHAKPCLB_02852 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NHAKPCLB_02853 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NHAKPCLB_02854 9.8e-313 yoeA - - V - - - MATE efflux family protein
NHAKPCLB_02855 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NHAKPCLB_02856 5.64e-32 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NHAKPCLB_02857 9.06e-65 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NHAKPCLB_02858 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NHAKPCLB_02859 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
NHAKPCLB_02860 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHAKPCLB_02861 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHAKPCLB_02862 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHAKPCLB_02863 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHAKPCLB_02864 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NHAKPCLB_02865 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NHAKPCLB_02866 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NHAKPCLB_02867 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NHAKPCLB_02868 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NHAKPCLB_02869 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NHAKPCLB_02870 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NHAKPCLB_02871 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NHAKPCLB_02872 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NHAKPCLB_02873 2.46e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NHAKPCLB_02874 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NHAKPCLB_02875 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHAKPCLB_02876 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NHAKPCLB_02877 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NHAKPCLB_02878 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
NHAKPCLB_02879 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
NHAKPCLB_02880 5.18e-81 yqhP - - - - - - -
NHAKPCLB_02881 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NHAKPCLB_02882 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NHAKPCLB_02883 1.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NHAKPCLB_02884 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NHAKPCLB_02885 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHAKPCLB_02886 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHAKPCLB_02887 2.72e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NHAKPCLB_02888 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHAKPCLB_02889 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
NHAKPCLB_02890 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NHAKPCLB_02891 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NHAKPCLB_02892 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NHAKPCLB_02893 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NHAKPCLB_02894 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
NHAKPCLB_02895 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
NHAKPCLB_02896 2.84e-36 yqzE - - S - - - YqzE-like protein
NHAKPCLB_02897 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NHAKPCLB_02898 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NHAKPCLB_02899 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NHAKPCLB_02900 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
NHAKPCLB_02901 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NHAKPCLB_02902 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NHAKPCLB_02903 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHAKPCLB_02904 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
NHAKPCLB_02905 8.73e-233 yqxL - - P - - - Mg2 transporter protein
NHAKPCLB_02906 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NHAKPCLB_02907 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHAKPCLB_02909 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NHAKPCLB_02910 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NHAKPCLB_02911 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NHAKPCLB_02912 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
NHAKPCLB_02913 7.34e-66 yqgV - - S - - - Thiamine-binding protein
NHAKPCLB_02914 2.69e-256 yqgU - - - - - - -
NHAKPCLB_02915 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NHAKPCLB_02916 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NHAKPCLB_02917 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NHAKPCLB_02918 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
NHAKPCLB_02919 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NHAKPCLB_02920 3.38e-14 yqgO - - - - - - -
NHAKPCLB_02921 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHAKPCLB_02922 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHAKPCLB_02923 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
NHAKPCLB_02925 2.81e-67 yqzD - - - - - - -
NHAKPCLB_02926 1.09e-93 yqzC - - S - - - YceG-like family
NHAKPCLB_02927 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHAKPCLB_02928 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHAKPCLB_02929 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NHAKPCLB_02930 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NHAKPCLB_02931 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NHAKPCLB_02932 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NHAKPCLB_02933 1.09e-290 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NHAKPCLB_02934 1.31e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NHAKPCLB_02935 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NHAKPCLB_02936 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
NHAKPCLB_02937 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
NHAKPCLB_02938 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NHAKPCLB_02939 2.38e-80 yqfX - - S - - - membrane
NHAKPCLB_02940 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NHAKPCLB_02941 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NHAKPCLB_02942 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NHAKPCLB_02943 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NHAKPCLB_02944 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHAKPCLB_02945 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHAKPCLB_02946 3.73e-46 yqfQ - - S - - - YqfQ-like protein
NHAKPCLB_02947 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NHAKPCLB_02948 4.21e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHAKPCLB_02949 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NHAKPCLB_02950 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NHAKPCLB_02951 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHAKPCLB_02952 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHAKPCLB_02953 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NHAKPCLB_02954 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHAKPCLB_02955 3.29e-144 ccpN - - K - - - CBS domain
NHAKPCLB_02956 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NHAKPCLB_02957 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NHAKPCLB_02958 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NHAKPCLB_02959 5.29e-27 - - - S - - - YqzL-like protein
NHAKPCLB_02960 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHAKPCLB_02961 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHAKPCLB_02962 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NHAKPCLB_02963 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHAKPCLB_02964 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NHAKPCLB_02966 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NHAKPCLB_02967 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NHAKPCLB_02968 2.07e-60 yqfC - - S - - - sporulation protein YqfC
NHAKPCLB_02969 2.23e-56 yqfB - - - - - - -
NHAKPCLB_02970 4.35e-192 yqfA - - S - - - UPF0365 protein
NHAKPCLB_02971 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NHAKPCLB_02972 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NHAKPCLB_02973 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NHAKPCLB_02974 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NHAKPCLB_02975 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NHAKPCLB_02976 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHAKPCLB_02977 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NHAKPCLB_02978 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHAKPCLB_02979 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NHAKPCLB_02980 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHAKPCLB_02981 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHAKPCLB_02982 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NHAKPCLB_02983 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHAKPCLB_02984 2.28e-66 yqxA - - S - - - Protein of unknown function (DUF3679)
NHAKPCLB_02985 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NHAKPCLB_02986 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NHAKPCLB_02987 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NHAKPCLB_02988 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NHAKPCLB_02989 2.36e-22 - - - S - - - YqzM-like protein
NHAKPCLB_02990 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NHAKPCLB_02991 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NHAKPCLB_02992 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NHAKPCLB_02993 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHAKPCLB_02994 5.44e-176 yqeM - - Q - - - Methyltransferase
NHAKPCLB_02995 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHAKPCLB_02996 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NHAKPCLB_02997 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHAKPCLB_02998 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NHAKPCLB_02999 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHAKPCLB_03000 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHAKPCLB_03001 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NHAKPCLB_03003 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NHAKPCLB_03004 1.44e-177 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_03005 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
NHAKPCLB_03006 2.98e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
NHAKPCLB_03007 7.4e-168 - - - - - - - -
NHAKPCLB_03008 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
NHAKPCLB_03009 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_03010 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHAKPCLB_03011 1.14e-197 yybE - - K - - - Transcriptional regulator
NHAKPCLB_03012 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
NHAKPCLB_03014 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NHAKPCLB_03015 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHAKPCLB_03016 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NHAKPCLB_03017 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NHAKPCLB_03019 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
NHAKPCLB_03020 1.1e-20 - - - S - - - SMI1 / KNR4 family
NHAKPCLB_03021 5.24e-60 - - - - - - - -
NHAKPCLB_03026 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
NHAKPCLB_03027 1.89e-40 - - - - - - - -
NHAKPCLB_03028 3.49e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NHAKPCLB_03029 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NHAKPCLB_03030 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHAKPCLB_03031 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHAKPCLB_03032 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHAKPCLB_03033 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHAKPCLB_03034 6.97e-189 yerO - - K - - - Transcriptional regulator
NHAKPCLB_03035 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHAKPCLB_03036 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHAKPCLB_03037 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHAKPCLB_03038 1.14e-27 - - - - - - - -
NHAKPCLB_03039 0.0 - - - K - - - SIR2-like domain
NHAKPCLB_03041 1.41e-72 - - - S - - - Protein of unknown function, DUF600
NHAKPCLB_03042 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NHAKPCLB_03043 1.25e-123 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
NHAKPCLB_03044 1.06e-73 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
NHAKPCLB_03045 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
NHAKPCLB_03047 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
NHAKPCLB_03049 9.52e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_03050 1.55e-59 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NHAKPCLB_03051 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NHAKPCLB_03052 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NHAKPCLB_03053 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
NHAKPCLB_03054 6.29e-133 yesL - - S - - - Protein of unknown function, DUF624
NHAKPCLB_03055 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_03056 2.41e-199 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NHAKPCLB_03057 7.99e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHAKPCLB_03058 1.17e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHAKPCLB_03059 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHAKPCLB_03060 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NHAKPCLB_03061 0.0 yesS - - K - - - Transcriptional regulator
NHAKPCLB_03062 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
NHAKPCLB_03063 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
NHAKPCLB_03064 2.32e-144 - - - S - - - Protein of unknown function, DUF624
NHAKPCLB_03065 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NHAKPCLB_03066 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NHAKPCLB_03067 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
NHAKPCLB_03068 2.73e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NHAKPCLB_03069 8.37e-153 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NHAKPCLB_03070 2.97e-193 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NHAKPCLB_03071 2.25e-127 yetA - - - - - - -
NHAKPCLB_03072 5.02e-234 yetA - - - - - - -
NHAKPCLB_03073 1.54e-213 yetA - - - - - - -
NHAKPCLB_03074 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NHAKPCLB_03075 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NHAKPCLB_03076 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NHAKPCLB_03077 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NHAKPCLB_03078 3.66e-157 yetF - - S - - - membrane
NHAKPCLB_03079 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NHAKPCLB_03080 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_03081 3.28e-44 - - - - - - - -
NHAKPCLB_03082 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHAKPCLB_03083 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
NHAKPCLB_03084 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NHAKPCLB_03085 1.3e-38 yetM - - CH - - - FAD binding domain
NHAKPCLB_03086 6.72e-171 - - - M - - - Membrane
NHAKPCLB_03087 2.17e-224 - - - L - - - Replication protein
NHAKPCLB_03089 9.66e-92 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
NHAKPCLB_03090 5.09e-304 pre - - D - - - plasmid recombination enzyme
NHAKPCLB_03091 1.81e-108 - - - K - - - Transcriptional regulator
NHAKPCLB_03096 1.24e-22 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
NHAKPCLB_03097 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHAKPCLB_03098 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHAKPCLB_03100 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NHAKPCLB_03101 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_03102 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_03103 4.47e-103 - - - T - - - HPP family
NHAKPCLB_03104 2.23e-17 - - - S - - - CGNR zinc finger
NHAKPCLB_03106 7.27e-55 - - - - - - - -
NHAKPCLB_03107 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NHAKPCLB_03108 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NHAKPCLB_03109 1.73e-13 - - - - - - - -
NHAKPCLB_03110 3.96e-84 - - - O - - - Papain family cysteine protease
NHAKPCLB_03112 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
NHAKPCLB_03113 3.82e-37 - - - - - - - -
NHAKPCLB_03115 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHAKPCLB_03117 6.74e-30 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
NHAKPCLB_03119 5.37e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHAKPCLB_03120 5.98e-72 ypuD - - - - - - -
NHAKPCLB_03121 5.92e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHAKPCLB_03122 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NHAKPCLB_03123 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHAKPCLB_03124 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHAKPCLB_03125 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_03126 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NHAKPCLB_03127 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHAKPCLB_03128 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHAKPCLB_03129 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
NHAKPCLB_03130 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHAKPCLB_03131 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NHAKPCLB_03132 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NHAKPCLB_03133 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NHAKPCLB_03134 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NHAKPCLB_03135 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NHAKPCLB_03136 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NHAKPCLB_03137 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_03138 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_03139 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_03140 8.13e-245 rsiX - - - - - - -
NHAKPCLB_03141 2.28e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHAKPCLB_03142 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHAKPCLB_03143 1.78e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHAKPCLB_03144 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NHAKPCLB_03145 1.28e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NHAKPCLB_03146 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NHAKPCLB_03147 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NHAKPCLB_03148 5.04e-148 ypbE - - M - - - Lysin motif
NHAKPCLB_03149 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
NHAKPCLB_03150 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NHAKPCLB_03151 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHAKPCLB_03152 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NHAKPCLB_03153 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NHAKPCLB_03154 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NHAKPCLB_03155 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NHAKPCLB_03156 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NHAKPCLB_03157 2.57e-141 ypfA - - M - - - Flagellar protein YcgR
NHAKPCLB_03158 4.83e-30 - - - S - - - Family of unknown function (DUF5359)
NHAKPCLB_03159 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NHAKPCLB_03160 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NHAKPCLB_03161 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHAKPCLB_03162 1.13e-11 - - - S - - - YpzI-like protein
NHAKPCLB_03163 1.11e-133 yphA - - - - - - -
NHAKPCLB_03164 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
NHAKPCLB_03165 2.06e-38 ypzH - - - - - - -
NHAKPCLB_03166 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NHAKPCLB_03167 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NHAKPCLB_03168 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
NHAKPCLB_03169 8.71e-176 yphF - - - - - - -
NHAKPCLB_03170 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NHAKPCLB_03171 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHAKPCLB_03172 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NHAKPCLB_03173 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NHAKPCLB_03174 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NHAKPCLB_03175 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHAKPCLB_03176 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHAKPCLB_03177 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHAKPCLB_03178 1.5e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NHAKPCLB_03179 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHAKPCLB_03180 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHAKPCLB_03181 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NHAKPCLB_03182 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHAKPCLB_03183 5e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHAKPCLB_03184 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NHAKPCLB_03185 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NHAKPCLB_03186 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHAKPCLB_03187 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHAKPCLB_03188 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHAKPCLB_03189 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NHAKPCLB_03190 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHAKPCLB_03191 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
NHAKPCLB_03192 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
NHAKPCLB_03193 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
NHAKPCLB_03194 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NHAKPCLB_03195 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NHAKPCLB_03196 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NHAKPCLB_03197 1.15e-125 ypjA - - S - - - membrane
NHAKPCLB_03198 6.56e-181 ypjB - - S - - - sporulation protein
NHAKPCLB_03199 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NHAKPCLB_03200 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NHAKPCLB_03201 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHAKPCLB_03202 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NHAKPCLB_03203 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NHAKPCLB_03204 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NHAKPCLB_03205 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHAKPCLB_03206 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHAKPCLB_03207 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NHAKPCLB_03208 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NHAKPCLB_03209 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NHAKPCLB_03210 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NHAKPCLB_03211 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NHAKPCLB_03212 2.66e-102 ypmB - - S - - - protein conserved in bacteria
NHAKPCLB_03213 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NHAKPCLB_03214 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NHAKPCLB_03215 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NHAKPCLB_03216 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHAKPCLB_03217 1.43e-121 ypoC - - - - - - -
NHAKPCLB_03218 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NHAKPCLB_03219 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHAKPCLB_03220 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
NHAKPCLB_03223 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
NHAKPCLB_03224 9.21e-11 - - - S - - - YppF-like protein
NHAKPCLB_03225 8.72e-68 yppG - - S - - - YppG-like protein
NHAKPCLB_03226 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHAKPCLB_03227 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NHAKPCLB_03228 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NHAKPCLB_03229 1.98e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NHAKPCLB_03230 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
NHAKPCLB_03231 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHAKPCLB_03232 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NHAKPCLB_03234 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NHAKPCLB_03235 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_03236 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NHAKPCLB_03237 1.57e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
NHAKPCLB_03238 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NHAKPCLB_03239 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NHAKPCLB_03240 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NHAKPCLB_03241 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NHAKPCLB_03242 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHAKPCLB_03243 1.43e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NHAKPCLB_03244 3.58e-263 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NHAKPCLB_03245 9.54e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NHAKPCLB_03246 0.0 ypbR - - S - - - Dynamin family
NHAKPCLB_03247 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
NHAKPCLB_03248 1.08e-11 - - - - - - - -
NHAKPCLB_03249 2.26e-213 ypcP - - L - - - 5'3' exonuclease
NHAKPCLB_03250 2.59e-05 - - - - ko:K06429 - ko00000 -
NHAKPCLB_03251 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NHAKPCLB_03252 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NHAKPCLB_03253 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NHAKPCLB_03254 7.99e-41 ypeQ - - S - - - Zinc-finger
NHAKPCLB_03255 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
NHAKPCLB_03256 1.17e-22 degR - - - - - - -
NHAKPCLB_03257 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NHAKPCLB_03258 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NHAKPCLB_03259 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHAKPCLB_03260 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NHAKPCLB_03261 2.42e-140 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NHAKPCLB_03262 2.32e-203 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NHAKPCLB_03263 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NHAKPCLB_03264 2.78e-98 yphP - - S - - - Belongs to the UPF0403 family
NHAKPCLB_03265 8.04e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NHAKPCLB_03266 2.01e-147 ypjP - - S - - - YpjP-like protein
NHAKPCLB_03267 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NHAKPCLB_03268 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHAKPCLB_03269 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHAKPCLB_03270 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NHAKPCLB_03271 1.29e-232 yplP - - K - - - Transcriptional regulator
NHAKPCLB_03272 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHAKPCLB_03273 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
NHAKPCLB_03274 6.15e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NHAKPCLB_03275 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NHAKPCLB_03276 5.59e-128 ypmS - - S - - - protein conserved in bacteria
NHAKPCLB_03277 8.69e-40 ypmT - - S - - - Uncharacterized ympT
NHAKPCLB_03278 7.03e-290 mepA - - V - - - MATE efflux family protein
NHAKPCLB_03279 4.14e-94 ypoP - - K - - - transcriptional
NHAKPCLB_03280 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHAKPCLB_03281 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NHAKPCLB_03282 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NHAKPCLB_03283 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NHAKPCLB_03284 9.37e-228 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NHAKPCLB_03285 2.74e-60 cgeA - - - ko:K06319 - ko00000 -
NHAKPCLB_03286 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
NHAKPCLB_03287 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NHAKPCLB_03288 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NHAKPCLB_03290 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHAKPCLB_03292 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHAKPCLB_03293 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NHAKPCLB_03294 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NHAKPCLB_03295 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NHAKPCLB_03296 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
NHAKPCLB_03297 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
NHAKPCLB_03298 7.44e-159 yodN - - - - - - -
NHAKPCLB_03300 2.11e-33 yozD - - S - - - YozD-like protein
NHAKPCLB_03301 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NHAKPCLB_03302 1.17e-71 yodL - - S - - - YodL-like
NHAKPCLB_03303 2.08e-12 - - - - - - - -
NHAKPCLB_03304 6.86e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NHAKPCLB_03305 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NHAKPCLB_03306 4.86e-41 yodI - - - - - - -
NHAKPCLB_03307 3.03e-166 yodH - - Q - - - Methyltransferase
NHAKPCLB_03308 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NHAKPCLB_03309 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHAKPCLB_03310 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
NHAKPCLB_03311 2.4e-60 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NHAKPCLB_03312 6.06e-136 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NHAKPCLB_03313 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NHAKPCLB_03314 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NHAKPCLB_03315 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
NHAKPCLB_03316 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NHAKPCLB_03317 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
NHAKPCLB_03318 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
NHAKPCLB_03319 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
NHAKPCLB_03320 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
NHAKPCLB_03321 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
NHAKPCLB_03322 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NHAKPCLB_03323 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NHAKPCLB_03324 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NHAKPCLB_03325 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NHAKPCLB_03327 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
NHAKPCLB_03328 1.89e-35 - - - S - - - YhzD-like protein
NHAKPCLB_03329 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_03330 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NHAKPCLB_03331 9.44e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NHAKPCLB_03332 0.0 yhaN - - L - - - AAA domain
NHAKPCLB_03333 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NHAKPCLB_03334 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
NHAKPCLB_03335 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHAKPCLB_03336 5.71e-116 yhaK - - S - - - Putative zincin peptidase
NHAKPCLB_03337 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NHAKPCLB_03338 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NHAKPCLB_03339 1.74e-54 yhaH - - S - - - YtxH-like protein
NHAKPCLB_03340 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
NHAKPCLB_03341 7.5e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHAKPCLB_03342 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHAKPCLB_03343 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NHAKPCLB_03344 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NHAKPCLB_03345 9.67e-160 ecsC - - S - - - EcsC protein family
NHAKPCLB_03346 8.54e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHAKPCLB_03347 5.44e-312 yhfA - - C - - - membrane
NHAKPCLB_03348 1e-44 - - - C - - - Rubrerythrin
NHAKPCLB_03349 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NHAKPCLB_03350 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NHAKPCLB_03351 6.13e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NHAKPCLB_03352 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NHAKPCLB_03353 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NHAKPCLB_03354 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_03355 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NHAKPCLB_03356 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHAKPCLB_03357 2.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NHAKPCLB_03358 1.55e-252 yhfE - - G - - - peptidase M42
NHAKPCLB_03359 1.79e-92 - - - S - - - ASCH
NHAKPCLB_03360 2.76e-288 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHAKPCLB_03361 9.84e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NHAKPCLB_03362 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NHAKPCLB_03363 2.13e-143 yhfK - - GM - - - NmrA-like family
NHAKPCLB_03364 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NHAKPCLB_03365 2.28e-84 yhfM - - - - - - -
NHAKPCLB_03366 9.64e-308 yhfN - - O - - - Peptidase M48
NHAKPCLB_03367 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NHAKPCLB_03368 1.47e-100 - - - K - - - acetyltransferase
NHAKPCLB_03369 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NHAKPCLB_03370 1.53e-220 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NHAKPCLB_03371 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NHAKPCLB_03372 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NHAKPCLB_03373 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NHAKPCLB_03374 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NHAKPCLB_03375 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NHAKPCLB_03376 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NHAKPCLB_03377 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NHAKPCLB_03378 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NHAKPCLB_03379 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_03380 9.84e-45 yhzC - - S - - - IDEAL
NHAKPCLB_03381 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NHAKPCLB_03382 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NHAKPCLB_03383 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
NHAKPCLB_03384 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHAKPCLB_03385 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
NHAKPCLB_03386 4.13e-78 yhjD - - - - - - -
NHAKPCLB_03387 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
NHAKPCLB_03388 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHAKPCLB_03389 0.0 yhjG - - CH - - - FAD binding domain
NHAKPCLB_03390 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_03393 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NHAKPCLB_03394 2.69e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NHAKPCLB_03395 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
NHAKPCLB_03396 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NHAKPCLB_03397 5.09e-238 yhjM - - K - - - Transcriptional regulator
NHAKPCLB_03398 4.83e-257 yhjN - - S ko:K07120 - ko00000 membrane
NHAKPCLB_03399 3.19e-266 - - - EGP - - - Transmembrane secretion effector
NHAKPCLB_03400 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
NHAKPCLB_03401 9.46e-198 yknT - - - ko:K06437 - ko00000 -
NHAKPCLB_03402 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHAKPCLB_03403 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHAKPCLB_03404 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NHAKPCLB_03405 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NHAKPCLB_03406 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NHAKPCLB_03407 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NHAKPCLB_03408 5.2e-260 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_03409 1.25e-95 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_03410 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_03411 1.31e-150 yknW - - S - - - Yip1 domain
NHAKPCLB_03412 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHAKPCLB_03413 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_03414 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NHAKPCLB_03415 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_03416 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NHAKPCLB_03417 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NHAKPCLB_03418 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NHAKPCLB_03419 5.43e-52 ykoA - - - - - - -
NHAKPCLB_03420 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHAKPCLB_03421 3.74e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHAKPCLB_03422 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHAKPCLB_03423 1.09e-18 - - - S - - - Uncharacterized protein YkpC
NHAKPCLB_03424 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NHAKPCLB_03425 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NHAKPCLB_03426 4.22e-305 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NHAKPCLB_03427 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NHAKPCLB_03428 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NHAKPCLB_03429 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHAKPCLB_03430 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHAKPCLB_03431 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
NHAKPCLB_03432 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
NHAKPCLB_03433 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHAKPCLB_03434 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NHAKPCLB_03435 6.41e-52 ykyA - - L - - - Putative cell-wall binding lipoprotein
NHAKPCLB_03436 6.37e-86 ykyA - - L - - - Putative cell-wall binding lipoprotein
NHAKPCLB_03437 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHAKPCLB_03438 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHAKPCLB_03439 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHAKPCLB_03440 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHAKPCLB_03441 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NHAKPCLB_03442 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NHAKPCLB_03443 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
NHAKPCLB_03444 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
NHAKPCLB_03445 4.48e-35 ykzI - - - - - - -
NHAKPCLB_03446 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NHAKPCLB_03447 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
NHAKPCLB_03450 5.37e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHAKPCLB_03452 1.92e-145 - - - S - - - Helix-turn-helix domain
NHAKPCLB_03453 6.09e-40 - - - L - - - Phage integrase family
NHAKPCLB_03455 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHAKPCLB_03456 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NHAKPCLB_03457 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NHAKPCLB_03458 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
NHAKPCLB_03459 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
NHAKPCLB_03460 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NHAKPCLB_03461 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NHAKPCLB_03462 2.83e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NHAKPCLB_03463 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
NHAKPCLB_03464 6.55e-223 yvdE - - K - - - Transcriptional regulator
NHAKPCLB_03465 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NHAKPCLB_03466 1.27e-39 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NHAKPCLB_03467 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NHAKPCLB_03468 1.07e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NHAKPCLB_03469 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHAKPCLB_03470 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NHAKPCLB_03471 1.05e-179 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NHAKPCLB_03472 1.38e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
NHAKPCLB_03473 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHAKPCLB_03474 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NHAKPCLB_03475 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NHAKPCLB_03476 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NHAKPCLB_03477 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NHAKPCLB_03478 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NHAKPCLB_03479 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHAKPCLB_03480 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHAKPCLB_03481 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NHAKPCLB_03482 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NHAKPCLB_03483 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NHAKPCLB_03485 0.0 - - - - - - - -
NHAKPCLB_03486 1.29e-111 - - - - - - - -
NHAKPCLB_03487 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NHAKPCLB_03488 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHAKPCLB_03489 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHAKPCLB_03490 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHAKPCLB_03491 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NHAKPCLB_03492 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHAKPCLB_03493 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHAKPCLB_03494 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHAKPCLB_03495 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
NHAKPCLB_03496 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
NHAKPCLB_03497 5.71e-48 yrhC - - S - - - YrhC-like protein
NHAKPCLB_03498 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NHAKPCLB_03499 3.91e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NHAKPCLB_03500 1.14e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHAKPCLB_03501 2.83e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NHAKPCLB_03502 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
NHAKPCLB_03503 1.65e-101 yrrS - - S - - - Protein of unknown function (DUF1510)
NHAKPCLB_03504 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NHAKPCLB_03505 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHAKPCLB_03506 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NHAKPCLB_03507 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NHAKPCLB_03508 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NHAKPCLB_03509 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NHAKPCLB_03510 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHAKPCLB_03511 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
NHAKPCLB_03512 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHAKPCLB_03513 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
NHAKPCLB_03514 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHAKPCLB_03515 1.25e-241 yrrI - - S - - - AI-2E family transporter
NHAKPCLB_03516 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NHAKPCLB_03517 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NHAKPCLB_03518 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_03519 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NHAKPCLB_03520 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
NHAKPCLB_03521 8.4e-42 yrzR - - - - - - -
NHAKPCLB_03522 1.38e-105 yrrD - - S - - - protein conserved in bacteria
NHAKPCLB_03523 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHAKPCLB_03524 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
NHAKPCLB_03525 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHAKPCLB_03526 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NHAKPCLB_03527 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_03528 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NHAKPCLB_03529 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NHAKPCLB_03530 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHAKPCLB_03531 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NHAKPCLB_03533 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NHAKPCLB_03534 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHAKPCLB_03535 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHAKPCLB_03536 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHAKPCLB_03537 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NHAKPCLB_03538 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NHAKPCLB_03539 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NHAKPCLB_03540 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHAKPCLB_03541 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
NHAKPCLB_03542 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_03543 8.64e-145 yrbG - - S - - - membrane
NHAKPCLB_03544 6.2e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
NHAKPCLB_03545 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NHAKPCLB_03546 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHAKPCLB_03547 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHAKPCLB_03548 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
NHAKPCLB_03549 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHAKPCLB_03550 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHAKPCLB_03551 1.85e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NHAKPCLB_03552 0.0 csbX - - EGP - - - the major facilitator superfamily
NHAKPCLB_03553 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NHAKPCLB_03554 5.47e-151 yrzF - - T - - - serine threonine protein kinase
NHAKPCLB_03556 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
NHAKPCLB_03557 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
NHAKPCLB_03558 3.51e-164 yebC - - K - - - transcriptional regulatory protein
NHAKPCLB_03559 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHAKPCLB_03560 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NHAKPCLB_03561 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHAKPCLB_03562 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NHAKPCLB_03563 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NHAKPCLB_03564 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NHAKPCLB_03565 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NHAKPCLB_03566 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NHAKPCLB_03567 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NHAKPCLB_03568 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHAKPCLB_03569 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NHAKPCLB_03570 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NHAKPCLB_03571 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NHAKPCLB_03572 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NHAKPCLB_03573 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NHAKPCLB_03574 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NHAKPCLB_03575 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NHAKPCLB_03576 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NHAKPCLB_03577 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NHAKPCLB_03578 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NHAKPCLB_03579 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NHAKPCLB_03580 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NHAKPCLB_03581 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NHAKPCLB_03582 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NHAKPCLB_03583 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NHAKPCLB_03584 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NHAKPCLB_03585 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHAKPCLB_03586 1.53e-35 - - - - - - - -
NHAKPCLB_03587 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHAKPCLB_03588 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NHAKPCLB_03589 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NHAKPCLB_03590 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NHAKPCLB_03591 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NHAKPCLB_03592 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NHAKPCLB_03593 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NHAKPCLB_03594 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NHAKPCLB_03595 4.77e-116 ysxD - - - - - - -
NHAKPCLB_03596 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NHAKPCLB_03597 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NHAKPCLB_03598 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NHAKPCLB_03599 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHAKPCLB_03600 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHAKPCLB_03601 4.53e-239 ysoA - - H - - - Tetratricopeptide repeat
NHAKPCLB_03602 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHAKPCLB_03603 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHAKPCLB_03604 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHAKPCLB_03605 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHAKPCLB_03606 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHAKPCLB_03607 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NHAKPCLB_03608 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NHAKPCLB_03610 1.38e-84 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NHAKPCLB_03611 4.77e-181 ysnF - - S - - - protein conserved in bacteria
NHAKPCLB_03613 4.83e-30 ykzE - - - - - - -
NHAKPCLB_03614 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NHAKPCLB_03615 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_03616 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHAKPCLB_03618 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NHAKPCLB_03619 6.78e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NHAKPCLB_03620 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHAKPCLB_03621 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NHAKPCLB_03622 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NHAKPCLB_03623 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NHAKPCLB_03624 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NHAKPCLB_03625 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NHAKPCLB_03626 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
NHAKPCLB_03628 7.14e-75 eag - - - - - - -
NHAKPCLB_03629 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NHAKPCLB_03630 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NHAKPCLB_03631 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NHAKPCLB_03632 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NHAKPCLB_03633 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NHAKPCLB_03634 1.94e-226 ykvI - - S - - - membrane
NHAKPCLB_03635 4.34e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHAKPCLB_03636 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NHAKPCLB_03637 1.69e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHAKPCLB_03638 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NHAKPCLB_03639 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
NHAKPCLB_03640 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NHAKPCLB_03641 2.6e-39 - - - - - - - -
NHAKPCLB_03642 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NHAKPCLB_03643 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHAKPCLB_03644 2.76e-115 stoA - - CO - - - thiol-disulfide
NHAKPCLB_03645 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NHAKPCLB_03646 3.99e-09 - - - - - - - -
NHAKPCLB_03647 2.74e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NHAKPCLB_03648 2.69e-229 ykvZ - - K - - - Transcriptional regulator
NHAKPCLB_03650 1.39e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NHAKPCLB_03651 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_03652 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NHAKPCLB_03653 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHAKPCLB_03654 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_03655 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NHAKPCLB_03656 1.86e-163 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_03657 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NHAKPCLB_03658 6.67e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NHAKPCLB_03659 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
NHAKPCLB_03660 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NHAKPCLB_03661 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NHAKPCLB_03663 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NHAKPCLB_03664 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NHAKPCLB_03665 4.3e-124 yrhH - - Q - - - methyltransferase
NHAKPCLB_03666 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NHAKPCLB_03667 2.35e-201 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NHAKPCLB_03668 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NHAKPCLB_03669 6.32e-59 yrhK - - S - - - YrhK-like protein
NHAKPCLB_03670 3.76e-287 oatA - - I - - - Acyltransferase family
NHAKPCLB_03671 2.18e-84 oatA - - I - - - Acyltransferase family
NHAKPCLB_03672 2.88e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
NHAKPCLB_03673 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_03674 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
NHAKPCLB_03675 5.63e-137 yrhP - - E - - - LysE type translocator
NHAKPCLB_03676 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_03677 0.0 levR - - K - - - PTS system fructose IIA component
NHAKPCLB_03678 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NHAKPCLB_03679 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
NHAKPCLB_03680 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NHAKPCLB_03681 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NHAKPCLB_03682 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NHAKPCLB_03683 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NHAKPCLB_03684 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NHAKPCLB_03685 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
NHAKPCLB_03686 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NHAKPCLB_03687 4.9e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
NHAKPCLB_03688 6.11e-36 yraE - - - ko:K06440 - ko00000 -
NHAKPCLB_03689 3.71e-283 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHAKPCLB_03690 9.61e-84 yraF - - M - - - Spore coat protein
NHAKPCLB_03691 4.04e-48 yraG - - - ko:K06440 - ko00000 -
NHAKPCLB_03692 1.1e-85 - - - E - - - Glyoxalase-like domain
NHAKPCLB_03693 1.05e-81 - - - T - - - sh3 domain protein
NHAKPCLB_03694 6.61e-80 - - - T - - - sh3 domain protein
NHAKPCLB_03695 1.05e-178 - - - S - - - Alpha beta hydrolase
NHAKPCLB_03696 8.42e-55 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_03697 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NHAKPCLB_03698 5.72e-238 yrpG - - C - - - Aldo/keto reductase family
NHAKPCLB_03699 3.7e-123 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_03700 6.26e-168 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NHAKPCLB_03702 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
NHAKPCLB_03703 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NHAKPCLB_03704 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NHAKPCLB_03705 1.48e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NHAKPCLB_03706 2.01e-118 yrdA - - S - - - DinB family
NHAKPCLB_03708 1.09e-73 - - - S - - - Protein of unknown function (DUF2568)
NHAKPCLB_03709 7.38e-131 yrdC - - Q - - - Isochorismatase family
NHAKPCLB_03711 1.16e-284 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NHAKPCLB_03712 3.92e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NHAKPCLB_03713 4.45e-99 bkdR - - K - - - helix_turn_helix ASNC type
NHAKPCLB_03714 2.1e-117 azlC - - E - - - AzlC protein
NHAKPCLB_03715 2.79e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
NHAKPCLB_03716 9.63e-290 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NHAKPCLB_03718 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NHAKPCLB_03719 5e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NHAKPCLB_03720 1.4e-203 - - - K - - - Transcriptional regulator
NHAKPCLB_03721 3.17e-212 yrdR - - EG - - - EamA-like transporter family
NHAKPCLB_03722 2.45e-23 - - - S - - - YrzO-like protein
NHAKPCLB_03723 6.17e-299 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NHAKPCLB_03724 8.79e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NHAKPCLB_03725 1.4e-264 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_03726 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
NHAKPCLB_03729 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
NHAKPCLB_03732 2.43e-14 - - - - - - - -
NHAKPCLB_03733 5.08e-26 xkdM - - S - - - Phage tail tube protein
NHAKPCLB_03735 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
NHAKPCLB_03736 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NHAKPCLB_03737 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NHAKPCLB_03738 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NHAKPCLB_03739 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NHAKPCLB_03740 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NHAKPCLB_03741 5.44e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NHAKPCLB_03742 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
NHAKPCLB_03743 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NHAKPCLB_03744 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_03745 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NHAKPCLB_03746 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
NHAKPCLB_03747 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHAKPCLB_03748 5.14e-161 yfmS - - NT - - - chemotaxis protein
NHAKPCLB_03749 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHAKPCLB_03750 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NHAKPCLB_03751 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NHAKPCLB_03752 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NHAKPCLB_03753 5.3e-47 - - - - - - - -
NHAKPCLB_03754 3.26e-72 - - - L - - - transposase activity
NHAKPCLB_03755 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
NHAKPCLB_03756 4.98e-30 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NHAKPCLB_03758 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
NHAKPCLB_03759 1.46e-201 - - - I - - - Alpha/beta hydrolase family
NHAKPCLB_03760 1.08e-188 yeaA - - S - - - Protein of unknown function (DUF4003)
NHAKPCLB_03761 8.17e-25 yeaA - - S - - - Protein of unknown function (DUF4003)
NHAKPCLB_03762 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NHAKPCLB_03763 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_03764 4.82e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHAKPCLB_03765 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NHAKPCLB_03766 2.63e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NHAKPCLB_03767 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NHAKPCLB_03768 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NHAKPCLB_03770 1.33e-280 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NHAKPCLB_03771 5.85e-165 yebC - - M - - - Membrane
NHAKPCLB_03773 2.66e-120 yebE - - S - - - UPF0316 protein
NHAKPCLB_03774 3.13e-38 yebG - - S - - - NETI protein
NHAKPCLB_03775 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHAKPCLB_03776 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHAKPCLB_03777 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHAKPCLB_03778 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NHAKPCLB_03779 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHAKPCLB_03780 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHAKPCLB_03781 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHAKPCLB_03782 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHAKPCLB_03783 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NHAKPCLB_03784 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHAKPCLB_03785 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NHAKPCLB_03786 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NHAKPCLB_03787 1.11e-95 - - - K - - - helix_turn_helix ASNC type
NHAKPCLB_03788 1.87e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NHAKPCLB_03789 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NHAKPCLB_03790 1.25e-239 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NHAKPCLB_03791 6.27e-67 yerC - - S - - - protein conserved in bacteria
NHAKPCLB_03792 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NHAKPCLB_03794 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NHAKPCLB_03795 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NHAKPCLB_03796 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHAKPCLB_03797 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NHAKPCLB_03798 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
NHAKPCLB_03799 2.17e-38 - - - - - - - -
NHAKPCLB_03801 1.78e-73 ydfR - - S - - - Protein of unknown function (DUF421)
NHAKPCLB_03802 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
NHAKPCLB_03803 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
NHAKPCLB_03804 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NHAKPCLB_03805 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
NHAKPCLB_03806 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
NHAKPCLB_03807 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
NHAKPCLB_03808 5.76e-70 - - - S - - - DoxX-like family
NHAKPCLB_03809 8.04e-111 yycN - - K - - - Acetyltransferase
NHAKPCLB_03810 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NHAKPCLB_03811 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_03812 5.94e-118 - - - S - - - DinB family
NHAKPCLB_03813 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NHAKPCLB_03814 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NHAKPCLB_03815 6.42e-147 ydgI - - C - - - nitroreductase
NHAKPCLB_03816 1.9e-89 - - - K - - - Winged helix DNA-binding domain
NHAKPCLB_03817 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NHAKPCLB_03818 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NHAKPCLB_03819 1.24e-156 ydhC - - K - - - FCD
NHAKPCLB_03820 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
NHAKPCLB_03821 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHAKPCLB_03822 4.28e-163 - - - - - - - -
NHAKPCLB_03823 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NHAKPCLB_03824 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NHAKPCLB_03826 3.12e-107 - - - K - - - Acetyltransferase (GNAT) domain
NHAKPCLB_03827 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NHAKPCLB_03828 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
NHAKPCLB_03829 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NHAKPCLB_03830 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_03831 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_03832 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHAKPCLB_03833 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHAKPCLB_03834 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NHAKPCLB_03835 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NHAKPCLB_03836 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NHAKPCLB_03837 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NHAKPCLB_03838 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NHAKPCLB_03839 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NHAKPCLB_03840 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
NHAKPCLB_03843 6.7e-222 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
NHAKPCLB_03844 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHAKPCLB_03845 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHAKPCLB_03846 9.55e-88 yqhY - - S - - - protein conserved in bacteria
NHAKPCLB_03847 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHAKPCLB_03848 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHAKPCLB_03849 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHAKPCLB_03850 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHAKPCLB_03851 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NHAKPCLB_03852 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHAKPCLB_03853 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NHAKPCLB_03854 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NHAKPCLB_03855 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NHAKPCLB_03856 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NHAKPCLB_03857 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NHAKPCLB_03859 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NHAKPCLB_03860 4.74e-37 - - - - - - - -
NHAKPCLB_03861 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NHAKPCLB_03862 3.02e-171 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NHAKPCLB_03863 6.65e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NHAKPCLB_03864 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NHAKPCLB_03865 7.33e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NHAKPCLB_03866 6.46e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NHAKPCLB_03867 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NHAKPCLB_03868 3.58e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NHAKPCLB_03869 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NHAKPCLB_03870 0.0 bkdR - - KT - - - Transcriptional regulator
NHAKPCLB_03871 7.1e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NHAKPCLB_03872 7.81e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NHAKPCLB_03873 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NHAKPCLB_03874 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHAKPCLB_03875 1.58e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHAKPCLB_03876 8.08e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHAKPCLB_03877 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHAKPCLB_03878 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NHAKPCLB_03879 8.11e-222 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NHAKPCLB_03880 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHAKPCLB_03881 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
NHAKPCLB_03882 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NHAKPCLB_03883 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NHAKPCLB_03884 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NHAKPCLB_03885 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NHAKPCLB_03886 6.92e-128 yqjB - - S - - - protein conserved in bacteria
NHAKPCLB_03888 7.75e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NHAKPCLB_03889 1.61e-30 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHAKPCLB_03890 7.25e-28 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHAKPCLB_03891 1.36e-265 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHAKPCLB_03892 3.04e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NHAKPCLB_03893 4.5e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
NHAKPCLB_03894 3.93e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHAKPCLB_03895 2.51e-32 yqzJ - - - - - - -
NHAKPCLB_03896 5.26e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHAKPCLB_03897 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHAKPCLB_03898 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHAKPCLB_03899 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHAKPCLB_03900 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NHAKPCLB_03901 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHAKPCLB_03902 9.3e-102 yhjR - - S - - - Rubrerythrin
NHAKPCLB_03903 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NHAKPCLB_03904 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NHAKPCLB_03905 1.34e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHAKPCLB_03906 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NHAKPCLB_03907 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
NHAKPCLB_03908 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NHAKPCLB_03909 3.92e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NHAKPCLB_03910 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NHAKPCLB_03911 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NHAKPCLB_03912 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
NHAKPCLB_03913 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NHAKPCLB_03914 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
NHAKPCLB_03915 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
NHAKPCLB_03916 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NHAKPCLB_03917 1.44e-74 yisL - - S - - - UPF0344 protein
NHAKPCLB_03918 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NHAKPCLB_03919 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
NHAKPCLB_03920 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NHAKPCLB_03921 4.02e-151 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NHAKPCLB_03922 7.14e-311 yisQ - - V - - - Mate efflux family protein
NHAKPCLB_03923 1.16e-206 yisR - - K - - - Transcriptional regulator
NHAKPCLB_03924 5.88e-232 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NHAKPCLB_03925 2.11e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NHAKPCLB_03926 1.41e-119 yisT - - S - - - DinB family
NHAKPCLB_03927 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NHAKPCLB_03928 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_03929 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
NHAKPCLB_03930 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHAKPCLB_03931 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
NHAKPCLB_03932 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
NHAKPCLB_03933 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NHAKPCLB_03934 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NHAKPCLB_03935 1.59e-203 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NHAKPCLB_03937 7.32e-49 yitR - - S - - - Domain of unknown function (DUF3784)
NHAKPCLB_03938 4.16e-198 yitS - - S - - - protein conserved in bacteria
NHAKPCLB_03939 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NHAKPCLB_03940 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
NHAKPCLB_03941 7.41e-37 - - - S - - - Protein of unknown function (DUF3813)
NHAKPCLB_03942 1.92e-08 - - - - - - - -
NHAKPCLB_03943 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NHAKPCLB_03944 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NHAKPCLB_03945 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NHAKPCLB_03946 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
NHAKPCLB_03947 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NHAKPCLB_03948 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
NHAKPCLB_03949 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
NHAKPCLB_03950 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHAKPCLB_03951 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHAKPCLB_03952 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NHAKPCLB_03953 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NHAKPCLB_03954 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NHAKPCLB_03955 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NHAKPCLB_03956 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHAKPCLB_03957 8.62e-269 VCP - - O - - - AAA domain (dynein-related subfamily)
NHAKPCLB_03958 2.71e-103 yjoA - - S - - - DinB family
NHAKPCLB_03959 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NHAKPCLB_03960 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NHAKPCLB_03961 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NHAKPCLB_03962 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NHAKPCLB_03963 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
NHAKPCLB_03964 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_03965 1.6e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NHAKPCLB_03966 3.22e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NHAKPCLB_03967 8.48e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
NHAKPCLB_03968 1.81e-315 - - - G ko:K03292 - ko00000 symporter YjmB
NHAKPCLB_03969 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NHAKPCLB_03970 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NHAKPCLB_03971 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NHAKPCLB_03972 1.16e-55 yjlB - - S - - - Cupin domain
NHAKPCLB_03973 1.26e-20 yjlB - - S - - - Cupin domain
NHAKPCLB_03974 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NHAKPCLB_03975 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NHAKPCLB_03976 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NHAKPCLB_03977 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NHAKPCLB_03978 1.11e-41 - - - - - - - -
NHAKPCLB_03979 7.18e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHAKPCLB_03980 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NHAKPCLB_03982 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NHAKPCLB_03984 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
NHAKPCLB_03985 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NHAKPCLB_03986 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NHAKPCLB_03987 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
NHAKPCLB_03988 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
NHAKPCLB_03989 9.97e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NHAKPCLB_03990 1.13e-29 yjfB - - S - - - Putative motility protein
NHAKPCLB_03991 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
NHAKPCLB_03992 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NHAKPCLB_03994 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHAKPCLB_03995 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
NHAKPCLB_03996 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
NHAKPCLB_03997 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHAKPCLB_03999 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NHAKPCLB_04002 4.78e-152 - - - L - - - Bacterial dnaA protein
NHAKPCLB_04003 6.98e-279 - - - L - - - Transposase
NHAKPCLB_04004 1.62e-37 - - - S - - - Protein of unknown function (DUF1433)
NHAKPCLB_04005 7.74e-301 - - - I - - - Pfam Lipase (class 3)
NHAKPCLB_04006 1.82e-55 - - - - - - - -
NHAKPCLB_04008 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHAKPCLB_04013 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHAKPCLB_04014 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHAKPCLB_04015 3.12e-192 ypuA - - S - - - Secreted protein
NHAKPCLB_04016 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHAKPCLB_04017 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NHAKPCLB_04018 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
NHAKPCLB_04019 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NHAKPCLB_04020 1.21e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NHAKPCLB_04021 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NHAKPCLB_04022 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NHAKPCLB_04023 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NHAKPCLB_04024 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHAKPCLB_04025 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NHAKPCLB_04026 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NHAKPCLB_04027 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NHAKPCLB_04028 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHAKPCLB_04029 2.28e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHAKPCLB_04030 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NHAKPCLB_04031 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NHAKPCLB_04032 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NHAKPCLB_04033 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NHAKPCLB_04034 1.47e-41 yqkK - - - - - - -
NHAKPCLB_04035 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NHAKPCLB_04036 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NHAKPCLB_04037 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NHAKPCLB_04038 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NHAKPCLB_04039 3.18e-77 ansR - - K - - - Transcriptional regulator
NHAKPCLB_04040 1.45e-280 yqxK - - L - - - DNA helicase
NHAKPCLB_04041 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NHAKPCLB_04042 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
NHAKPCLB_04043 3.61e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NHAKPCLB_04044 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
NHAKPCLB_04045 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NHAKPCLB_04046 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
NHAKPCLB_04047 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
NHAKPCLB_04048 6.8e-250 yqkA - - K - - - GrpB protein
NHAKPCLB_04049 2.63e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NHAKPCLB_04050 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NHAKPCLB_04051 1.87e-65 yqiX - - S - - - YolD-like protein
NHAKPCLB_04052 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHAKPCLB_04054 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
NHAKPCLB_04056 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHAKPCLB_04057 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NHAKPCLB_04058 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NHAKPCLB_04059 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NHAKPCLB_04060 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NHAKPCLB_04061 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHAKPCLB_04062 0.0 rocB - - E - - - arginine degradation protein
NHAKPCLB_04063 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NHAKPCLB_04065 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NHAKPCLB_04066 1.29e-140 yheG - - GM - - - NAD(P)H-binding
NHAKPCLB_04067 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_04068 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NHAKPCLB_04069 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
NHAKPCLB_04070 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NHAKPCLB_04071 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NHAKPCLB_04072 5.03e-194 nodB1 - - G - - - deacetylase
NHAKPCLB_04073 8.05e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NHAKPCLB_04074 3.04e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NHAKPCLB_04075 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
NHAKPCLB_04076 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NHAKPCLB_04077 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHAKPCLB_04078 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHAKPCLB_04079 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NHAKPCLB_04080 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NHAKPCLB_04081 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NHAKPCLB_04082 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NHAKPCLB_04083 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NHAKPCLB_04084 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHAKPCLB_04085 2.74e-243 yhdN - - C - - - Aldo keto reductase
NHAKPCLB_04086 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NHAKPCLB_04087 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
NHAKPCLB_04088 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
NHAKPCLB_04089 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHAKPCLB_04090 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_04091 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHAKPCLB_04092 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
NHAKPCLB_04093 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHAKPCLB_04094 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NHAKPCLB_04095 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NHAKPCLB_04096 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NHAKPCLB_04097 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NHAKPCLB_04098 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NHAKPCLB_04099 1.51e-306 ygxB - - M - - - Conserved TM helix
NHAKPCLB_04100 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NHAKPCLB_04101 4.06e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NHAKPCLB_04102 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
NHAKPCLB_04103 1.65e-51 yhdB - - S - - - YhdB-like protein
NHAKPCLB_04104 2.7e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NHAKPCLB_04105 1.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_04106 1.27e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_04107 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NHAKPCLB_04108 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NHAKPCLB_04109 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHAKPCLB_04110 4.68e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NHAKPCLB_04111 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NHAKPCLB_04112 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHAKPCLB_04113 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHAKPCLB_04114 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
NHAKPCLB_04115 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
NHAKPCLB_04116 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
NHAKPCLB_04117 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NHAKPCLB_04118 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NHAKPCLB_04119 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NHAKPCLB_04120 8.34e-128 yhcQ - - M - - - Spore coat protein
NHAKPCLB_04121 1.01e-217 yhcP - - - - - - -
NHAKPCLB_04122 6e-104 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHAKPCLB_04123 9.39e-63 yhcM - - - - - - -
NHAKPCLB_04125 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_04126 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
NHAKPCLB_04127 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NHAKPCLB_04128 3.19e-111 yddI - - - - - - -
NHAKPCLB_04129 1.03e-237 yddH - - M - - - Lysozyme-like
NHAKPCLB_04130 1.94e-180 yddG - - S - - - maturation of SSU-rRNA
NHAKPCLB_04131 3.65e-81 ynaC - - - - - - -
NHAKPCLB_04132 9.3e-51 ynaC - - - - - - -
NHAKPCLB_04133 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
NHAKPCLB_04134 4.13e-51 - - - - - - - -
NHAKPCLB_04135 1.46e-105 - - - - - - - -
NHAKPCLB_04137 1.68e-13 - - - - - - - -
NHAKPCLB_04138 3.12e-09 - - - - - - - -
NHAKPCLB_04139 6.2e-28 - - - S - - - Domain of unknown function (DUF4917)
NHAKPCLB_04140 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHAKPCLB_04141 3.25e-72 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NHAKPCLB_04142 4.08e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NHAKPCLB_04143 3.19e-41 xhlB - - S - - - SPP1 phage holin
NHAKPCLB_04144 4.44e-38 bhlA - - S - - - BhlA holin family
NHAKPCLB_04147 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NHAKPCLB_04148 1.19e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
NHAKPCLB_04149 1.38e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHAKPCLB_04150 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NHAKPCLB_04151 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NHAKPCLB_04152 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NHAKPCLB_04153 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NHAKPCLB_04154 0.0 ycgA - - S - - - Membrane
NHAKPCLB_04155 7.79e-105 ycgB - - - - - - -
NHAKPCLB_04156 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NHAKPCLB_04157 7.37e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NHAKPCLB_04158 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NHAKPCLB_04159 2.38e-82 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NHAKPCLB_04160 1.33e-268 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NHAKPCLB_04161 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NHAKPCLB_04162 8.63e-97 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NHAKPCLB_04163 2.99e-117 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NHAKPCLB_04164 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHAKPCLB_04165 1.08e-139 tmrB - - S - - - AAA domain
NHAKPCLB_04166 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHAKPCLB_04167 8.92e-96 - - - - - - - -
NHAKPCLB_04168 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
NHAKPCLB_04171 2.43e-162 - - - S - - - Domain of unknown function, YrpD
NHAKPCLB_04173 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHAKPCLB_04176 7.54e-22 - - - - - - - -
NHAKPCLB_04177 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NHAKPCLB_04179 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHAKPCLB_04180 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHAKPCLB_04181 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NHAKPCLB_04185 4.46e-153 - - - E - - - amino acid
NHAKPCLB_04186 9.13e-135 ywqM - - K - - - Transcriptional regulator
NHAKPCLB_04187 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
NHAKPCLB_04188 9.99e-59 - - - - - - - -
NHAKPCLB_04189 1.35e-169 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHAKPCLB_04190 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NHAKPCLB_04191 2.98e-53 - - - - - - - -
NHAKPCLB_04195 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
NHAKPCLB_04196 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NHAKPCLB_04197 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NHAKPCLB_04198 5.97e-174 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHAKPCLB_04199 2.44e-210 - - - K - - - AraC-like ligand binding domain
NHAKPCLB_04200 4.71e-83 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHAKPCLB_04201 5.69e-105 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHAKPCLB_04202 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NHAKPCLB_04203 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_04204 3.74e-24 ydeG - - EGP - - - Major facilitator superfamily
NHAKPCLB_04205 1.16e-234 ydeG - - EGP - - - Major facilitator superfamily
NHAKPCLB_04206 3.21e-70 ydeH - - - - - - -
NHAKPCLB_04207 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NHAKPCLB_04208 3.64e-142 - - - - - - - -
NHAKPCLB_04209 2.51e-36 - - - S - - - SNARE associated Golgi protein
NHAKPCLB_04210 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
NHAKPCLB_04211 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
NHAKPCLB_04212 9.01e-195 ydeK - - EG - - - -transporter
NHAKPCLB_04213 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_04214 8.69e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NHAKPCLB_04215 2.7e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
NHAKPCLB_04216 4.66e-16 - - - K - - - HxlR-like helix-turn-helix
NHAKPCLB_04217 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NHAKPCLB_04218 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NHAKPCLB_04219 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHAKPCLB_04220 8.66e-186 - - - J - - - GNAT acetyltransferase
NHAKPCLB_04221 9.99e-197 - - - EG - - - EamA-like transporter family
NHAKPCLB_04222 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHAKPCLB_04223 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
NHAKPCLB_04224 4.04e-149 ydfE - - S - - - Flavin reductase like domain
NHAKPCLB_04225 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NHAKPCLB_04226 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHAKPCLB_04228 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NHAKPCLB_04229 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHAKPCLB_04230 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NHAKPCLB_04231 2.2e-222 - - - S - - - Alpha/beta hydrolase family
NHAKPCLB_04232 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NHAKPCLB_04233 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
NHAKPCLB_04234 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHAKPCLB_04235 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NHAKPCLB_04236 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NHAKPCLB_04237 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
NHAKPCLB_04238 2.1e-71 ydfQ - - CO - - - Thioredoxin
NHAKPCLB_04239 1.8e-87 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NHAKPCLB_04240 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHAKPCLB_04241 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NHAKPCLB_04247 1.27e-07 - - - S - - - peptidoglycan catabolic process
NHAKPCLB_04248 1.14e-20 - - - S - - - peptidoglycan catabolic process
NHAKPCLB_04249 2.45e-34 - - - K - - - Helix-turn-helix domain
NHAKPCLB_04250 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
NHAKPCLB_04251 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NHAKPCLB_04252 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NHAKPCLB_04253 2.78e-272 xylR - - GK - - - ROK family
NHAKPCLB_04254 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NHAKPCLB_04255 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NHAKPCLB_04257 4.67e-90 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NHAKPCLB_04258 5.28e-83 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NHAKPCLB_04259 1.11e-111 yddI - - - - - - -
NHAKPCLB_04260 2.82e-235 yddH - - M - - - Lysozyme-like
NHAKPCLB_04261 1.56e-128 - - - - - - - -
NHAKPCLB_04262 7.11e-181 yddG - - S - - - maturation of SSU-rRNA
NHAKPCLB_04263 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_04264 0.0 lytB - - D - - - Stage II sporulation protein
NHAKPCLB_04265 1.39e-15 - - - - - - - -
NHAKPCLB_04266 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NHAKPCLB_04267 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHAKPCLB_04268 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NHAKPCLB_04269 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NHAKPCLB_04270 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NHAKPCLB_04271 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NHAKPCLB_04272 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NHAKPCLB_04273 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NHAKPCLB_04274 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NHAKPCLB_04275 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NHAKPCLB_04276 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NHAKPCLB_04277 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NHAKPCLB_04278 3.42e-157 yflK - - S - - - protein conserved in bacteria
NHAKPCLB_04279 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
NHAKPCLB_04280 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
NHAKPCLB_04281 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NHAKPCLB_04282 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NHAKPCLB_04283 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NHAKPCLB_04284 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NHAKPCLB_04285 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
NHAKPCLB_04286 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NHAKPCLB_04287 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NHAKPCLB_04288 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NHAKPCLB_04289 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NHAKPCLB_04290 6.16e-160 frp - - C - - - nitroreductase
NHAKPCLB_04291 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NHAKPCLB_04292 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NHAKPCLB_04296 0.00063 - - - L - - - Pfam:DUF955
NHAKPCLB_04301 1.79e-74 - - - S - - - Bacteriophage holin family
NHAKPCLB_04302 6.14e-142 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NHAKPCLB_04305 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NHAKPCLB_04317 7.33e-144 - - - L - - - Integrase core domain
NHAKPCLB_04318 7.55e-59 orfX1 - - L - - - Transposase
NHAKPCLB_04326 2.14e-17 - - - Q - - - methyltransferase
NHAKPCLB_04327 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NHAKPCLB_04328 1.54e-114 yddE - - S - - - AAA-like domain
NHAKPCLB_04329 3.29e-73 - - - S - - - Domain of unknown function (DUF1874)
NHAKPCLB_04330 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
NHAKPCLB_04331 9.37e-114 yddE - - S - - - AAA-like domain
NHAKPCLB_04332 1.59e-65 - - - L - - - Transposase
NHAKPCLB_04333 1.51e-174 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
NHAKPCLB_04340 3.99e-53 - - - - - - - -
NHAKPCLB_04342 1.07e-57 - - - S - - - transposition, DNA-mediated
NHAKPCLB_04343 1.82e-28 - - - S - - - HTH-like domain
NHAKPCLB_04346 0.0 - - - V - - - Beta-lactamase
NHAKPCLB_04348 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NHAKPCLB_04350 4.82e-69 ynaF - - - - - - -
NHAKPCLB_04351 4.09e-128 yddE - - S - - - AAA-like domain
NHAKPCLB_04353 4.19e-20 ynaF - - - - - - -
NHAKPCLB_04355 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
NHAKPCLB_04356 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NHAKPCLB_04357 6.88e-84 - - - S - - - HTH-like domain
NHAKPCLB_04358 0.0 - - - L - - - AAA ATPase domain
NHAKPCLB_04359 0.0 - - - L - - - Superfamily I DNA and RNA helicases
NHAKPCLB_04360 0.0 - - - V - - - Abi-like protein
NHAKPCLB_04361 2.64e-42 - - - - - - - -
NHAKPCLB_04362 1.74e-95 - - - T - - - NACHT domain
NHAKPCLB_04363 3.75e-30 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)