ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
GKAFKPJL_00001 9.38e-95 ytwI - - S - - - membrane
GKAFKPJL_00002 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKAFKPJL_00003 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
GKAFKPJL_00004 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
GKAFKPJL_00005 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_00006 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
GKAFKPJL_00007 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKAFKPJL_00008 8.79e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKAFKPJL_00009 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
GKAFKPJL_00010 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKAFKPJL_00011 4.54e-205 ytbE - - S - - - reductase
GKAFKPJL_00012 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
GKAFKPJL_00013 9.85e-88 ytcD - - K - - - Transcriptional regulator
GKAFKPJL_00014 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKAFKPJL_00015 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GKAFKPJL_00016 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKAFKPJL_00017 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
GKAFKPJL_00018 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
GKAFKPJL_00019 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
GKAFKPJL_00020 2e-204 ytxC - - S - - - YtxC-like family
GKAFKPJL_00022 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKAFKPJL_00023 1.07e-245 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKAFKPJL_00024 1.13e-70 yhcM - - - - - - -
GKAFKPJL_00025 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKAFKPJL_00026 3.64e-223 yhcP - - - - - - -
GKAFKPJL_00027 1.68e-146 yhcQ - - M - - - Spore coat protein
GKAFKPJL_00028 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKAFKPJL_00029 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
GKAFKPJL_00030 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKAFKPJL_00031 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
GKAFKPJL_00032 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
GKAFKPJL_00033 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
GKAFKPJL_00034 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GKAFKPJL_00035 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKAFKPJL_00036 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GKAFKPJL_00037 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
GKAFKPJL_00038 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKAFKPJL_00039 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GKAFKPJL_00040 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
GKAFKPJL_00041 7.33e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_00042 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_00043 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
GKAFKPJL_00044 1.65e-51 yhdB - - S - - - YhdB-like protein
GKAFKPJL_00045 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
GKAFKPJL_00046 1.39e-274 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKAFKPJL_00047 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
GKAFKPJL_00048 5.29e-307 ygxB - - M - - - Conserved TM helix
GKAFKPJL_00049 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
GKAFKPJL_00050 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GKAFKPJL_00051 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKAFKPJL_00052 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_00053 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKAFKPJL_00054 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_00055 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
GKAFKPJL_00056 2.48e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GKAFKPJL_00057 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00058 2.05e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_00059 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
GKAFKPJL_00060 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
GKAFKPJL_00061 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_00062 6.74e-244 yhdN - - C - - - Aldo keto reductase
GKAFKPJL_00063 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GKAFKPJL_00064 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKAFKPJL_00065 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
GKAFKPJL_00066 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GKAFKPJL_00067 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
GKAFKPJL_00068 5.44e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKAFKPJL_00069 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKAFKPJL_00070 3.15e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKAFKPJL_00071 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
GKAFKPJL_00072 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
GKAFKPJL_00073 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GKAFKPJL_00074 1.63e-199 nodB1 - - G - - - deacetylase
GKAFKPJL_00075 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GKAFKPJL_00076 1.71e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GKAFKPJL_00077 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
GKAFKPJL_00078 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKAFKPJL_00079 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKAFKPJL_00080 1.29e-140 yheG - - GM - - - NAD(P)H-binding
GKAFKPJL_00081 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GKAFKPJL_00082 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
GKAFKPJL_00083 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
GKAFKPJL_00084 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
GKAFKPJL_00085 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
GKAFKPJL_00086 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
GKAFKPJL_00087 2.24e-262 yhaZ - - L - - - DNA alkylation repair enzyme
GKAFKPJL_00088 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
GKAFKPJL_00089 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
GKAFKPJL_00090 7.54e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
GKAFKPJL_00091 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GKAFKPJL_00093 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
GKAFKPJL_00094 2.29e-36 - - - S - - - YhzD-like protein
GKAFKPJL_00095 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_00096 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
GKAFKPJL_00097 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
GKAFKPJL_00098 0.0 yhaN - - L - - - AAA domain
GKAFKPJL_00099 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
GKAFKPJL_00100 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
GKAFKPJL_00101 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GKAFKPJL_00102 1.4e-116 yhaK - - S - - - Putative zincin peptidase
GKAFKPJL_00103 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
GKAFKPJL_00104 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
GKAFKPJL_00105 1.74e-54 yhaH - - S - - - YtxH-like protein
GKAFKPJL_00106 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
GKAFKPJL_00107 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKAFKPJL_00108 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GKAFKPJL_00109 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
GKAFKPJL_00110 1.72e-269 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
GKAFKPJL_00111 1.01e-161 ecsC - - S - - - EcsC protein family
GKAFKPJL_00112 1.48e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GKAFKPJL_00113 6.63e-313 yhfA - - C - - - membrane
GKAFKPJL_00114 2.31e-24 - - - C - - - Rubrerythrin
GKAFKPJL_00115 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
GKAFKPJL_00116 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKAFKPJL_00117 1.06e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GKAFKPJL_00118 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
GKAFKPJL_00119 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GKAFKPJL_00120 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_00121 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
GKAFKPJL_00122 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKAFKPJL_00123 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
GKAFKPJL_00124 2.68e-253 yhfE - - G - - - peptidase M42
GKAFKPJL_00125 6.22e-93 - - - S - - - ASCH
GKAFKPJL_00126 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKAFKPJL_00127 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GKAFKPJL_00128 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
GKAFKPJL_00129 1.01e-141 yhfK - - GM - - - NmrA-like family
GKAFKPJL_00130 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GKAFKPJL_00131 5.6e-85 yhfM - - - - - - -
GKAFKPJL_00132 9.64e-308 yhfN - - O - - - Peptidase M48
GKAFKPJL_00133 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_00134 8.5e-100 - - - K - - - acetyltransferase
GKAFKPJL_00135 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
GKAFKPJL_00136 2.27e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
GKAFKPJL_00137 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
GKAFKPJL_00138 7.05e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKAFKPJL_00139 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
GKAFKPJL_00140 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
GKAFKPJL_00141 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
GKAFKPJL_00142 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
GKAFKPJL_00143 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_00144 9.84e-45 yhzC - - S - - - IDEAL
GKAFKPJL_00145 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
GKAFKPJL_00146 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_00147 3.27e-53 yhjA - - S - - - Excalibur calcium-binding domain
GKAFKPJL_00148 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKAFKPJL_00149 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
GKAFKPJL_00150 2.57e-78 yhjD - - - - - - -
GKAFKPJL_00151 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
GKAFKPJL_00152 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKAFKPJL_00153 0.0 yhjG - - CH - - - FAD binding domain
GKAFKPJL_00154 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_00155 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
GKAFKPJL_00156 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GKAFKPJL_00157 1.52e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKAFKPJL_00158 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GKAFKPJL_00159 2.52e-238 yhjM - - K - - - Transcriptional regulator
GKAFKPJL_00160 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
GKAFKPJL_00161 1.04e-271 - - - EGP - - - Transmembrane secretion effector
GKAFKPJL_00162 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
GKAFKPJL_00163 2.19e-100 yhjR - - S - - - Rubrerythrin
GKAFKPJL_00164 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
GKAFKPJL_00165 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
GKAFKPJL_00166 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GKAFKPJL_00167 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
GKAFKPJL_00168 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
GKAFKPJL_00169 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
GKAFKPJL_00170 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
GKAFKPJL_00171 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
GKAFKPJL_00172 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
GKAFKPJL_00173 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
GKAFKPJL_00174 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
GKAFKPJL_00175 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
GKAFKPJL_00176 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
GKAFKPJL_00177 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GKAFKPJL_00178 1.02e-74 yisL - - S - - - UPF0344 protein
GKAFKPJL_00179 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_00180 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
GKAFKPJL_00181 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKAFKPJL_00182 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
GKAFKPJL_00183 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
GKAFKPJL_00184 1.01e-310 yisQ - - V - - - Mate efflux family protein
GKAFKPJL_00185 4.04e-207 yisR - - K - - - Transcriptional regulator
GKAFKPJL_00186 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
GKAFKPJL_00187 7.35e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
GKAFKPJL_00188 9.94e-120 yisT - - S - - - DinB family
GKAFKPJL_00189 2.08e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
GKAFKPJL_00190 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00191 8.75e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
GKAFKPJL_00192 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKAFKPJL_00193 1.17e-144 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GKAFKPJL_00194 6.26e-292 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GKAFKPJL_00195 3.87e-184 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GKAFKPJL_00196 1.38e-155 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
GKAFKPJL_00197 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
GKAFKPJL_00198 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKAFKPJL_00199 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKAFKPJL_00200 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_00201 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
GKAFKPJL_00202 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
GKAFKPJL_00203 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GKAFKPJL_00204 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
GKAFKPJL_00205 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
GKAFKPJL_00206 4.16e-122 - - - - - - - -
GKAFKPJL_00207 1.42e-218 - - - - - - - -
GKAFKPJL_00208 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
GKAFKPJL_00209 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
GKAFKPJL_00210 6.11e-120 - - - - - - - -
GKAFKPJL_00211 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
GKAFKPJL_00212 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GKAFKPJL_00213 9.13e-202 yitS - - S - - - protein conserved in bacteria
GKAFKPJL_00214 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKAFKPJL_00215 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
GKAFKPJL_00216 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
GKAFKPJL_00217 1.92e-08 - - - - - - - -
GKAFKPJL_00218 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKAFKPJL_00219 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GKAFKPJL_00220 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
GKAFKPJL_00221 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
GKAFKPJL_00222 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
GKAFKPJL_00223 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
GKAFKPJL_00224 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GKAFKPJL_00225 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GKAFKPJL_00226 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
GKAFKPJL_00227 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
GKAFKPJL_00228 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKAFKPJL_00229 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
GKAFKPJL_00230 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKAFKPJL_00231 2.51e-39 yjzC - - S - - - YjzC-like protein
GKAFKPJL_00232 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
GKAFKPJL_00233 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
GKAFKPJL_00234 5.41e-134 yjaV - - - - - - -
GKAFKPJL_00235 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
GKAFKPJL_00236 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
GKAFKPJL_00237 2.67e-38 yjzB - - - - - - -
GKAFKPJL_00238 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKAFKPJL_00239 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKAFKPJL_00240 9.48e-193 yjaZ - - O - - - Zn-dependent protease
GKAFKPJL_00241 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_00242 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_00243 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
GKAFKPJL_00244 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_00245 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_00246 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
GKAFKPJL_00247 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
GKAFKPJL_00248 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKAFKPJL_00249 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_00250 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_00251 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_00252 3.12e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_00253 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
GKAFKPJL_00254 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_00255 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKAFKPJL_00256 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
GKAFKPJL_00257 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GKAFKPJL_00258 5.97e-280 coiA - - S ko:K06198 - ko00000 Competence protein
GKAFKPJL_00259 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
GKAFKPJL_00260 2.68e-28 - - - - - - - -
GKAFKPJL_00262 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GKAFKPJL_00263 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
GKAFKPJL_00264 7.22e-129 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKAFKPJL_00265 4.94e-128 yjbK - - S - - - protein conserved in bacteria
GKAFKPJL_00266 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
GKAFKPJL_00267 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
GKAFKPJL_00268 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKAFKPJL_00269 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
GKAFKPJL_00270 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GKAFKPJL_00271 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GKAFKPJL_00272 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GKAFKPJL_00273 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
GKAFKPJL_00274 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
GKAFKPJL_00275 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
GKAFKPJL_00276 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GKAFKPJL_00277 2.94e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GKAFKPJL_00278 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKAFKPJL_00279 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
GKAFKPJL_00280 5.16e-104 yjbX - - S - - - Spore coat protein
GKAFKPJL_00281 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
GKAFKPJL_00282 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
GKAFKPJL_00283 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
GKAFKPJL_00284 9.3e-32 cotW - - - ko:K06341 - ko00000 -
GKAFKPJL_00285 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
GKAFKPJL_00286 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
GKAFKPJL_00289 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
GKAFKPJL_00290 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKAFKPJL_00291 6.31e-51 - - - - - - - -
GKAFKPJL_00292 9.05e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_00293 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
GKAFKPJL_00294 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
GKAFKPJL_00295 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKAFKPJL_00296 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
GKAFKPJL_00297 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
GKAFKPJL_00298 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GKAFKPJL_00299 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKAFKPJL_00300 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_00301 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_00302 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_00303 1.03e-69 - - - - - - - -
GKAFKPJL_00304 3.95e-59 yhcC - - - - - - -
GKAFKPJL_00305 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
GKAFKPJL_00306 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
GKAFKPJL_00307 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
GKAFKPJL_00308 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
GKAFKPJL_00309 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
GKAFKPJL_00310 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
GKAFKPJL_00311 4.28e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GKAFKPJL_00312 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
GKAFKPJL_00313 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
GKAFKPJL_00314 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKAFKPJL_00315 1.32e-223 yhbB - - S - - - Putative amidase domain
GKAFKPJL_00316 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKAFKPJL_00317 1.92e-147 yhzB - - S - - - B3/4 domain
GKAFKPJL_00319 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_00320 2.79e-102 ygaO - - - - - - -
GKAFKPJL_00321 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKAFKPJL_00323 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
GKAFKPJL_00324 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GKAFKPJL_00325 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
GKAFKPJL_00326 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GKAFKPJL_00327 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKAFKPJL_00329 0.0 ygaK - - C - - - Berberine and berberine like
GKAFKPJL_00330 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GKAFKPJL_00331 3.18e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
GKAFKPJL_00332 1.58e-36 - - - - - - - -
GKAFKPJL_00333 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
GKAFKPJL_00343 1.42e-302 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_00344 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
GKAFKPJL_00345 2.71e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
GKAFKPJL_00346 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
GKAFKPJL_00347 2.87e-120 - - - S - - - YcxB-like protein
GKAFKPJL_00348 7.69e-204 ycxC - - EG - - - EamA-like transporter family
GKAFKPJL_00349 2.69e-201 ycxD - - K - - - GntR family transcriptional regulator
GKAFKPJL_00350 1.33e-100 ycxD - - K - - - GntR family transcriptional regulator
GKAFKPJL_00351 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
GKAFKPJL_00352 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
GKAFKPJL_00353 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKAFKPJL_00354 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKAFKPJL_00355 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
GKAFKPJL_00356 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
GKAFKPJL_00357 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GKAFKPJL_00358 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GKAFKPJL_00359 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
GKAFKPJL_00360 2.82e-105 yclD - - - - - - -
GKAFKPJL_00361 2.15e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
GKAFKPJL_00362 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
GKAFKPJL_00363 0.0 yclG - - M - - - Pectate lyase superfamily protein
GKAFKPJL_00365 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GKAFKPJL_00366 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
GKAFKPJL_00367 3.8e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
GKAFKPJL_00368 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
GKAFKPJL_00369 2.27e-279 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
GKAFKPJL_00370 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_00371 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GKAFKPJL_00372 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKAFKPJL_00374 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GKAFKPJL_00376 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKAFKPJL_00377 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_00378 7.77e-210 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_00379 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_00380 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
GKAFKPJL_00381 0.0 ycnB - - EGP - - - the major facilitator superfamily
GKAFKPJL_00382 5.87e-198 ycnC - - K - - - Transcriptional regulator
GKAFKPJL_00383 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKAFKPJL_00384 1.68e-60 ycnE - - S - - - Monooxygenase
GKAFKPJL_00385 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKAFKPJL_00386 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00387 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKAFKPJL_00388 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKAFKPJL_00389 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
GKAFKPJL_00390 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_00391 3.99e-134 ycnI - - S - - - protein conserved in bacteria
GKAFKPJL_00392 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
GKAFKPJL_00393 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKAFKPJL_00394 1.34e-74 - - - - - - - -
GKAFKPJL_00395 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
GKAFKPJL_00396 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GKAFKPJL_00397 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
GKAFKPJL_00398 1.68e-255 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
GKAFKPJL_00400 1.78e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKAFKPJL_00401 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
GKAFKPJL_00402 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
GKAFKPJL_00404 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
GKAFKPJL_00405 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
GKAFKPJL_00406 1.08e-270 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
GKAFKPJL_00407 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
GKAFKPJL_00408 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
GKAFKPJL_00409 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
GKAFKPJL_00410 1.55e-170 kipR - - K - - - Transcriptional regulator
GKAFKPJL_00411 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
GKAFKPJL_00413 8.97e-65 yczJ - - S - - - biosynthesis
GKAFKPJL_00414 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
GKAFKPJL_00415 8.6e-220 ycsN - - S - - - Oxidoreductase
GKAFKPJL_00416 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
GKAFKPJL_00417 0.0 ydaB - - IQ - - - acyl-CoA ligase
GKAFKPJL_00418 1e-127 ydaC - - Q - - - Methyltransferase domain
GKAFKPJL_00419 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_00420 2.75e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
GKAFKPJL_00421 2.69e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKAFKPJL_00422 5.24e-101 ydaG - - S - - - general stress protein
GKAFKPJL_00423 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GKAFKPJL_00424 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
GKAFKPJL_00425 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GKAFKPJL_00426 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKAFKPJL_00427 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
GKAFKPJL_00428 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
GKAFKPJL_00429 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
GKAFKPJL_00430 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
GKAFKPJL_00431 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
GKAFKPJL_00432 0.0 ydaO - - E - - - amino acid
GKAFKPJL_00433 3.08e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GKAFKPJL_00434 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
GKAFKPJL_00435 2.14e-53 - - - - - - - -
GKAFKPJL_00436 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
GKAFKPJL_00437 1.67e-42 ydaS - - S - - - membrane
GKAFKPJL_00438 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GKAFKPJL_00439 1.75e-189 ydbA - - P - - - EcsC protein family
GKAFKPJL_00440 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
GKAFKPJL_00441 7.58e-79 ydbB - - G - - - Cupin domain
GKAFKPJL_00442 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
GKAFKPJL_00443 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
GKAFKPJL_00444 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GKAFKPJL_00445 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKAFKPJL_00446 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GKAFKPJL_00447 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKAFKPJL_00448 1.32e-230 ydbI - - S - - - AI-2E family transporter
GKAFKPJL_00449 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_00450 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKAFKPJL_00451 7.67e-69 ydbL - - - - - - -
GKAFKPJL_00452 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
GKAFKPJL_00453 1.49e-26 - - - S - - - Fur-regulated basic protein B
GKAFKPJL_00455 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKAFKPJL_00456 4.19e-75 ydbP - - CO - - - Thioredoxin
GKAFKPJL_00457 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
GKAFKPJL_00458 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKAFKPJL_00459 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKAFKPJL_00460 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
GKAFKPJL_00461 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
GKAFKPJL_00462 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
GKAFKPJL_00463 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKAFKPJL_00464 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
GKAFKPJL_00465 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKAFKPJL_00466 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GKAFKPJL_00467 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
GKAFKPJL_00468 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
GKAFKPJL_00469 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
GKAFKPJL_00470 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GKAFKPJL_00471 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
GKAFKPJL_00472 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
GKAFKPJL_00473 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GKAFKPJL_00474 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_00475 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
GKAFKPJL_00479 1.32e-106 ydcG - - S - - - EVE domain
GKAFKPJL_00480 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_00481 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
GKAFKPJL_00482 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
GKAFKPJL_00490 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
GKAFKPJL_00491 8.07e-41 - - - - - - - -
GKAFKPJL_00492 5.02e-24 - - - S - - - LXG domain of WXG superfamily
GKAFKPJL_00493 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
GKAFKPJL_00494 9.05e-56 - - - L - - - HNH nucleases
GKAFKPJL_00497 7.24e-08 - - - S - - - Putative amidase domain
GKAFKPJL_00500 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKAFKPJL_00501 1.72e-52 - - - - - - - -
GKAFKPJL_00505 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
GKAFKPJL_00506 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
GKAFKPJL_00507 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
GKAFKPJL_00508 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GKAFKPJL_00509 2.18e-213 - - - K - - - AraC-like ligand binding domain
GKAFKPJL_00510 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GKAFKPJL_00511 4.06e-209 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
GKAFKPJL_00512 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00513 5.15e-275 ydeG - - EGP - - - Major facilitator superfamily
GKAFKPJL_00514 9.2e-70 ydeH - - - - - - -
GKAFKPJL_00515 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
GKAFKPJL_00516 2.46e-140 - - - - - - - -
GKAFKPJL_00517 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
GKAFKPJL_00518 5.54e-146 - - - T - - - Transcriptional regulator
GKAFKPJL_00519 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
GKAFKPJL_00520 4.01e-92 - - - S - - - SNARE associated Golgi protein
GKAFKPJL_00521 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
GKAFKPJL_00522 1.72e-110 - - - K - - - Transcriptional regulator C-terminal region
GKAFKPJL_00524 1.49e-193 ydeK - - EG - - - -transporter
GKAFKPJL_00525 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00526 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
GKAFKPJL_00527 2.31e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
GKAFKPJL_00528 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
GKAFKPJL_00529 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKAFKPJL_00530 2.92e-90 ydeP - - K - - - Transcriptional regulator
GKAFKPJL_00531 2.36e-143 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
GKAFKPJL_00532 1.13e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
GKAFKPJL_00533 1.46e-133 ydeS - - K - - - Transcriptional regulator
GKAFKPJL_00534 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
GKAFKPJL_00535 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKAFKPJL_00536 8.77e-145 - - - J - - - GNAT acetyltransferase
GKAFKPJL_00537 9.56e-195 - - - EG - - - EamA-like transporter family
GKAFKPJL_00538 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKAFKPJL_00539 2.34e-148 ydfE - - S - - - Flavin reductase like domain
GKAFKPJL_00540 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKAFKPJL_00541 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKAFKPJL_00543 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_00544 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_00545 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
GKAFKPJL_00546 3.8e-223 - - - S - - - Alpha/beta hydrolase family
GKAFKPJL_00547 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
GKAFKPJL_00548 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
GKAFKPJL_00549 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKAFKPJL_00550 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
GKAFKPJL_00551 1.51e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKAFKPJL_00552 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
GKAFKPJL_00553 7.63e-74 ydfQ - - CO - - - Thioredoxin
GKAFKPJL_00554 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
GKAFKPJL_00555 5.33e-39 - - - - - - - -
GKAFKPJL_00557 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
GKAFKPJL_00558 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
GKAFKPJL_00559 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKAFKPJL_00560 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
GKAFKPJL_00561 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
GKAFKPJL_00562 4.04e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
GKAFKPJL_00563 1.93e-68 - - - S - - - DoxX-like family
GKAFKPJL_00564 2.46e-68 yycN - - K - - - Acetyltransferase
GKAFKPJL_00565 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
GKAFKPJL_00566 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_00567 2.32e-115 - - - S - - - DinB family
GKAFKPJL_00568 8.04e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_00569 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
GKAFKPJL_00570 9.12e-147 ydgI - - C - - - nitroreductase
GKAFKPJL_00571 6.63e-90 - - - K - - - Winged helix DNA-binding domain
GKAFKPJL_00572 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
GKAFKPJL_00573 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
GKAFKPJL_00574 4.31e-157 ydhC - - K - - - FCD
GKAFKPJL_00575 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
GKAFKPJL_00576 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GKAFKPJL_00577 4.79e-160 - - - - - - - -
GKAFKPJL_00578 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
GKAFKPJL_00579 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
GKAFKPJL_00581 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
GKAFKPJL_00582 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
GKAFKPJL_00583 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
GKAFKPJL_00584 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
GKAFKPJL_00585 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_00586 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_00587 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKAFKPJL_00588 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKAFKPJL_00589 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
GKAFKPJL_00590 4.94e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
GKAFKPJL_00591 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKAFKPJL_00592 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
GKAFKPJL_00593 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
GKAFKPJL_00596 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
GKAFKPJL_00597 8.66e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
GKAFKPJL_00598 1.9e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
GKAFKPJL_00599 1.24e-181 - - - J - - - FR47-like protein
GKAFKPJL_00600 3.09e-127 yobS - - K - - - Transcriptional regulator
GKAFKPJL_00601 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKAFKPJL_00602 6.32e-114 - - - K - - - Bacterial transcription activator, effector binding domain
GKAFKPJL_00603 1.97e-227 yobV - - K - - - WYL domain
GKAFKPJL_00604 6.07e-120 yobW - - - - - - -
GKAFKPJL_00605 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
GKAFKPJL_00606 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GKAFKPJL_00607 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
GKAFKPJL_00608 2.6e-185 - - - - - - - -
GKAFKPJL_00609 1.08e-121 yocC - - - - - - -
GKAFKPJL_00610 1.84e-136 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
GKAFKPJL_00611 6.62e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
GKAFKPJL_00612 2.37e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_00613 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_00614 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
GKAFKPJL_00615 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKAFKPJL_00616 2.42e-146 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKAFKPJL_00617 1.42e-107 yocK - - T - - - general stress protein
GKAFKPJL_00618 3.02e-70 yocL - - - - - - -
GKAFKPJL_00619 5.79e-43 - - - - - - - -
GKAFKPJL_00620 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKAFKPJL_00621 2.94e-55 yozN - - - - - - -
GKAFKPJL_00622 1.83e-49 yocN - - - - - - -
GKAFKPJL_00623 2.17e-74 yozO - - S - - - Bacterial PH domain
GKAFKPJL_00624 1.91e-42 yozC - - - - - - -
GKAFKPJL_00625 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKAFKPJL_00626 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
GKAFKPJL_00627 6.49e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
GKAFKPJL_00628 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GKAFKPJL_00629 7.79e-213 yocS - - S ko:K03453 - ko00000 -transporter
GKAFKPJL_00630 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GKAFKPJL_00631 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GKAFKPJL_00632 0.0 yojO - - P - - - Von Willebrand factor
GKAFKPJL_00633 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
GKAFKPJL_00634 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GKAFKPJL_00635 3.72e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
GKAFKPJL_00636 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
GKAFKPJL_00637 2.49e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKAFKPJL_00639 8.38e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
GKAFKPJL_00640 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKAFKPJL_00641 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
GKAFKPJL_00642 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
GKAFKPJL_00643 1.07e-57 - - - - - - - -
GKAFKPJL_00644 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
GKAFKPJL_00645 7.69e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
GKAFKPJL_00646 5.59e-14 - - - - - - - -
GKAFKPJL_00647 1.86e-289 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GKAFKPJL_00648 3.97e-84 iolK - - S - - - tautomerase
GKAFKPJL_00649 2.63e-73 yodB - - K - - - transcriptional
GKAFKPJL_00650 1.11e-139 yodC - - C - - - nitroreductase
GKAFKPJL_00651 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
GKAFKPJL_00652 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKAFKPJL_00653 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
GKAFKPJL_00654 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKAFKPJL_00655 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GKAFKPJL_00656 3.69e-167 yodH - - Q - - - Methyltransferase
GKAFKPJL_00657 2.93e-42 yodI - - - - - - -
GKAFKPJL_00658 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
GKAFKPJL_00659 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
GKAFKPJL_00660 2.08e-12 - - - - - - - -
GKAFKPJL_00661 1.17e-71 yodL - - S - - - YodL-like
GKAFKPJL_00662 2.33e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
GKAFKPJL_00663 5.18e-34 yozD - - S - - - YozD-like protein
GKAFKPJL_00665 1.29e-159 yodN - - - - - - -
GKAFKPJL_00666 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
GKAFKPJL_00667 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
GKAFKPJL_00668 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
GKAFKPJL_00669 4.33e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
GKAFKPJL_00670 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
GKAFKPJL_00671 2.71e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GKAFKPJL_00672 3.27e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKAFKPJL_00673 2.34e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GKAFKPJL_00675 9.78e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
GKAFKPJL_00676 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
GKAFKPJL_00677 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
GKAFKPJL_00678 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
GKAFKPJL_00679 3.86e-236 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
GKAFKPJL_00680 1.1e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
GKAFKPJL_00681 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GKAFKPJL_00682 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
GKAFKPJL_00683 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKAFKPJL_00684 4.14e-94 ypoP - - K - - - transcriptional
GKAFKPJL_00685 1.65e-288 mepA - - V - - - MATE efflux family protein
GKAFKPJL_00686 2.13e-40 ypmT - - S - - - Uncharacterized ympT
GKAFKPJL_00687 6.8e-129 ypmS - - S - - - protein conserved in bacteria
GKAFKPJL_00688 1.05e-177 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
GKAFKPJL_00689 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GKAFKPJL_00690 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
GKAFKPJL_00691 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKAFKPJL_00692 1.4e-236 yplP - - K - - - Transcriptional regulator
GKAFKPJL_00693 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
GKAFKPJL_00694 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GKAFKPJL_00695 9.58e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKAFKPJL_00696 9.52e-199 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKAFKPJL_00697 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GKAFKPJL_00698 1.16e-146 ypjP - - S - - - YpjP-like protein
GKAFKPJL_00699 1.14e-182 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
GKAFKPJL_00700 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
GKAFKPJL_00701 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
GKAFKPJL_00702 2.44e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
GKAFKPJL_00703 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
GKAFKPJL_00704 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
GKAFKPJL_00705 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKAFKPJL_00706 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GKAFKPJL_00707 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
GKAFKPJL_00708 1.17e-22 degR - - - - - - -
GKAFKPJL_00709 5.22e-41 - - - S - - - Protein of unknown function (DUF2564)
GKAFKPJL_00710 1.54e-37 ypeQ - - S - - - Zinc-finger
GKAFKPJL_00711 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
GKAFKPJL_00712 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GKAFKPJL_00713 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
GKAFKPJL_00714 5.23e-05 - - - - ko:K06429 - ko00000 -
GKAFKPJL_00715 2.26e-213 ypcP - - L - - - 5'3' exonuclease
GKAFKPJL_00716 1.08e-11 - - - - - - - -
GKAFKPJL_00717 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
GKAFKPJL_00718 0.0 ypbR - - S - - - Dynamin family
GKAFKPJL_00719 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
GKAFKPJL_00720 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
GKAFKPJL_00721 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GKAFKPJL_00722 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKAFKPJL_00723 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GKAFKPJL_00724 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
GKAFKPJL_00725 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
GKAFKPJL_00726 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
GKAFKPJL_00727 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
GKAFKPJL_00728 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GKAFKPJL_00729 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_00730 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
GKAFKPJL_00732 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
GKAFKPJL_00733 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKAFKPJL_00734 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
GKAFKPJL_00735 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
GKAFKPJL_00736 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GKAFKPJL_00737 7.43e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
GKAFKPJL_00738 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
GKAFKPJL_00739 1.45e-66 yppG - - S - - - YppG-like protein
GKAFKPJL_00740 9.21e-11 - - - S - - - YppF-like protein
GKAFKPJL_00741 7.14e-11 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
GKAFKPJL_00744 3.44e-236 yppC - - S - - - Protein of unknown function (DUF2515)
GKAFKPJL_00745 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKAFKPJL_00746 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKAFKPJL_00747 1.17e-120 ypoC - - - - - - -
GKAFKPJL_00748 5.92e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKAFKPJL_00749 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
GKAFKPJL_00750 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
GKAFKPJL_00751 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
GKAFKPJL_00752 2.27e-103 ypmB - - S - - - protein conserved in bacteria
GKAFKPJL_00753 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
GKAFKPJL_00754 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
GKAFKPJL_00755 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GKAFKPJL_00756 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GKAFKPJL_00757 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GKAFKPJL_00758 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKAFKPJL_00759 3.7e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKAFKPJL_00760 1.65e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
GKAFKPJL_00761 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
GKAFKPJL_00762 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
GKAFKPJL_00763 6.89e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKAFKPJL_00764 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
GKAFKPJL_00765 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKAFKPJL_00766 6.84e-183 ypjB - - S - - - sporulation protein
GKAFKPJL_00767 1.2e-127 ypjA - - S - - - membrane
GKAFKPJL_00768 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
GKAFKPJL_00769 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
GKAFKPJL_00770 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
GKAFKPJL_00771 1.86e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
GKAFKPJL_00772 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
GKAFKPJL_00773 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
GKAFKPJL_00774 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GKAFKPJL_00775 2e-263 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
GKAFKPJL_00776 3.7e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKAFKPJL_00777 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GKAFKPJL_00778 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GKAFKPJL_00779 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
GKAFKPJL_00780 4e-143 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
GKAFKPJL_00781 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKAFKPJL_00782 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKAFKPJL_00783 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GKAFKPJL_00784 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GKAFKPJL_00785 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKAFKPJL_00786 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
GKAFKPJL_00787 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GKAFKPJL_00788 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKAFKPJL_00789 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GKAFKPJL_00790 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GKAFKPJL_00791 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GKAFKPJL_00792 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
GKAFKPJL_00793 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKAFKPJL_00794 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GKAFKPJL_00795 2.5e-175 yphF - - - - - - -
GKAFKPJL_00796 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
GKAFKPJL_00797 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
GKAFKPJL_00798 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
GKAFKPJL_00799 5.91e-38 ypzH - - - - - - -
GKAFKPJL_00800 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
GKAFKPJL_00801 3.87e-134 yphA - - - - - - -
GKAFKPJL_00802 5.6e-12 - - - S - - - YpzI-like protein
GKAFKPJL_00803 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKAFKPJL_00804 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
GKAFKPJL_00805 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
GKAFKPJL_00806 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
GKAFKPJL_00807 1.04e-140 ypfA - - M - - - Flagellar protein YcgR
GKAFKPJL_00808 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
GKAFKPJL_00809 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
GKAFKPJL_00810 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
GKAFKPJL_00811 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
GKAFKPJL_00812 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKAFKPJL_00813 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GKAFKPJL_00814 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GKAFKPJL_00815 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
GKAFKPJL_00816 4.22e-139 ypbE - - M - - - Lysin motif
GKAFKPJL_00817 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
GKAFKPJL_00818 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKAFKPJL_00819 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
GKAFKPJL_00820 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
GKAFKPJL_00821 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKAFKPJL_00822 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKAFKPJL_00823 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GKAFKPJL_00824 1.49e-254 rsiX - - - - - - -
GKAFKPJL_00825 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_00826 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_00827 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_00828 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GKAFKPJL_00829 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
GKAFKPJL_00830 2.14e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GKAFKPJL_00831 1.81e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKAFKPJL_00832 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
GKAFKPJL_00833 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
GKAFKPJL_00834 1.13e-270 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKAFKPJL_00835 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
GKAFKPJL_00836 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKAFKPJL_00837 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKAFKPJL_00838 3.57e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
GKAFKPJL_00839 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_00840 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GKAFKPJL_00841 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKAFKPJL_00842 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
GKAFKPJL_00843 2.93e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKAFKPJL_00844 5.98e-72 ypuD - - - - - - -
GKAFKPJL_00845 1.18e-125 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
GKAFKPJL_00846 4.14e-21 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
GKAFKPJL_00848 3.82e-09 - - - S - - - SNARE associated Golgi protein
GKAFKPJL_00850 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKAFKPJL_00851 2.67e-193 ypuA - - S - - - Secreted protein
GKAFKPJL_00852 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKAFKPJL_00853 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
GKAFKPJL_00854 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
GKAFKPJL_00855 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
GKAFKPJL_00856 1.21e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
GKAFKPJL_00857 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
GKAFKPJL_00858 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
GKAFKPJL_00859 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
GKAFKPJL_00860 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_00861 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GKAFKPJL_00862 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
GKAFKPJL_00863 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKAFKPJL_00864 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKAFKPJL_00865 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKAFKPJL_00866 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
GKAFKPJL_00867 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
GKAFKPJL_00868 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
GKAFKPJL_00869 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GKAFKPJL_00870 3.73e-44 yqkK - - - - - - -
GKAFKPJL_00871 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GKAFKPJL_00872 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
GKAFKPJL_00873 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
GKAFKPJL_00874 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
GKAFKPJL_00875 3.18e-77 ansR - - K - - - Transcriptional regulator
GKAFKPJL_00876 2.62e-283 yqxK - - L - - - DNA helicase
GKAFKPJL_00877 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
GKAFKPJL_00878 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
GKAFKPJL_00879 8.88e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
GKAFKPJL_00880 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
GKAFKPJL_00881 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
GKAFKPJL_00882 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
GKAFKPJL_00883 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
GKAFKPJL_00884 2.89e-251 yqkA - - K - - - GrpB protein
GKAFKPJL_00885 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
GKAFKPJL_00886 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
GKAFKPJL_00887 1.87e-65 yqiX - - S - - - YolD-like protein
GKAFKPJL_00888 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKAFKPJL_00890 2.04e-289 yqjV - - G - - - Major Facilitator Superfamily
GKAFKPJL_00892 6.12e-92 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_00893 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
GKAFKPJL_00894 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
GKAFKPJL_00895 1.39e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_00896 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKAFKPJL_00897 9.98e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKAFKPJL_00898 0.0 rocB - - E - - - arginine degradation protein
GKAFKPJL_00899 4.94e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GKAFKPJL_00900 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKAFKPJL_00901 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKAFKPJL_00902 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKAFKPJL_00903 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKAFKPJL_00904 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKAFKPJL_00905 7.8e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKAFKPJL_00906 1.77e-32 yqzJ - - - - - - -
GKAFKPJL_00907 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKAFKPJL_00908 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
GKAFKPJL_00909 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
GKAFKPJL_00910 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GKAFKPJL_00911 4.49e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
GKAFKPJL_00913 2.41e-128 yqjB - - S - - - protein conserved in bacteria
GKAFKPJL_00914 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
GKAFKPJL_00915 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKAFKPJL_00916 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKAFKPJL_00917 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKAFKPJL_00918 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
GKAFKPJL_00919 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GKAFKPJL_00920 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_00921 7.45e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
GKAFKPJL_00922 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKAFKPJL_00923 1.98e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKAFKPJL_00924 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKAFKPJL_00925 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKAFKPJL_00926 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
GKAFKPJL_00927 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKAFKPJL_00928 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
GKAFKPJL_00929 0.0 bkdR - - KT - - - Transcriptional regulator
GKAFKPJL_00930 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
GKAFKPJL_00931 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GKAFKPJL_00932 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
GKAFKPJL_00933 2.63e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
GKAFKPJL_00934 1.65e-266 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
GKAFKPJL_00935 2.81e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
GKAFKPJL_00936 2.32e-280 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
GKAFKPJL_00937 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
GKAFKPJL_00938 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
GKAFKPJL_00939 2.26e-37 - - - - - - - -
GKAFKPJL_00940 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GKAFKPJL_00942 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GKAFKPJL_00943 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
GKAFKPJL_00944 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
GKAFKPJL_00945 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
GKAFKPJL_00946 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
GKAFKPJL_00947 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKAFKPJL_00948 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
GKAFKPJL_00949 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKAFKPJL_00950 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKAFKPJL_00951 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKAFKPJL_00952 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKAFKPJL_00953 1.65e-88 yqhY - - S - - - protein conserved in bacteria
GKAFKPJL_00954 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GKAFKPJL_00955 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKAFKPJL_00956 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
GKAFKPJL_00957 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
GKAFKPJL_00958 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
GKAFKPJL_00959 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
GKAFKPJL_00960 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
GKAFKPJL_00961 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
GKAFKPJL_00962 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
GKAFKPJL_00963 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
GKAFKPJL_00964 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
GKAFKPJL_00965 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKAFKPJL_00966 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GKAFKPJL_00967 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
GKAFKPJL_00968 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
GKAFKPJL_00969 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
GKAFKPJL_00970 5.18e-81 yqhP - - - - - - -
GKAFKPJL_00971 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GKAFKPJL_00972 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GKAFKPJL_00973 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GKAFKPJL_00974 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
GKAFKPJL_00975 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKAFKPJL_00976 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKAFKPJL_00977 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
GKAFKPJL_00978 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GKAFKPJL_00979 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
GKAFKPJL_00980 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
GKAFKPJL_00981 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
GKAFKPJL_00982 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
GKAFKPJL_00983 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
GKAFKPJL_00984 8e-156 yqxM - - - ko:K19433 - ko00000 -
GKAFKPJL_00985 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
GKAFKPJL_00986 3.33e-35 yqzE - - S - - - YqzE-like protein
GKAFKPJL_00987 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
GKAFKPJL_00988 9.65e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
GKAFKPJL_00989 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
GKAFKPJL_00990 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
GKAFKPJL_00991 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
GKAFKPJL_00992 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
GKAFKPJL_00993 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKAFKPJL_00995 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
GKAFKPJL_00996 1.51e-233 yqxL - - P - - - Mg2 transporter protein
GKAFKPJL_00997 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKAFKPJL_00998 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKAFKPJL_01000 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
GKAFKPJL_01001 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
GKAFKPJL_01002 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
GKAFKPJL_01003 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
GKAFKPJL_01004 7.34e-66 yqgV - - S - - - Thiamine-binding protein
GKAFKPJL_01005 2.69e-256 yqgU - - - - - - -
GKAFKPJL_01006 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
GKAFKPJL_01007 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKAFKPJL_01008 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
GKAFKPJL_01009 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
GKAFKPJL_01010 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
GKAFKPJL_01011 3.38e-14 yqgO - - - - - - -
GKAFKPJL_01012 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKAFKPJL_01013 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
GKAFKPJL_01014 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
GKAFKPJL_01016 2.81e-67 yqzD - - - - - - -
GKAFKPJL_01017 1.09e-93 yqzC - - S - - - YceG-like family
GKAFKPJL_01018 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKAFKPJL_01019 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKAFKPJL_01020 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
GKAFKPJL_01021 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
GKAFKPJL_01022 5.34e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
GKAFKPJL_01023 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
GKAFKPJL_01024 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
GKAFKPJL_01025 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
GKAFKPJL_01026 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
GKAFKPJL_01027 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
GKAFKPJL_01028 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
GKAFKPJL_01029 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GKAFKPJL_01030 2.38e-80 yqfX - - S - - - membrane
GKAFKPJL_01031 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
GKAFKPJL_01032 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
GKAFKPJL_01033 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKAFKPJL_01034 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
GKAFKPJL_01035 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GKAFKPJL_01036 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKAFKPJL_01037 4.89e-58 yqfQ - - S - - - YqfQ-like protein
GKAFKPJL_01038 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GKAFKPJL_01039 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKAFKPJL_01040 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
GKAFKPJL_01041 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GKAFKPJL_01042 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKAFKPJL_01043 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKAFKPJL_01044 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
GKAFKPJL_01045 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GKAFKPJL_01046 3.29e-144 ccpN - - K - - - CBS domain
GKAFKPJL_01047 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
GKAFKPJL_01048 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
GKAFKPJL_01049 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
GKAFKPJL_01050 5.29e-27 - - - S - - - YqzL-like protein
GKAFKPJL_01051 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKAFKPJL_01052 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GKAFKPJL_01053 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
GKAFKPJL_01054 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKAFKPJL_01055 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
GKAFKPJL_01057 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
GKAFKPJL_01058 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
GKAFKPJL_01059 2.07e-60 yqfC - - S - - - sporulation protein YqfC
GKAFKPJL_01060 3.13e-79 yqfB - - - - - - -
GKAFKPJL_01061 8.78e-192 yqfA - - S - - - UPF0365 protein
GKAFKPJL_01062 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
GKAFKPJL_01063 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
GKAFKPJL_01064 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
GKAFKPJL_01065 2.04e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
GKAFKPJL_01066 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
GKAFKPJL_01067 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKAFKPJL_01068 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
GKAFKPJL_01069 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKAFKPJL_01070 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
GKAFKPJL_01071 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKAFKPJL_01072 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKAFKPJL_01073 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
GKAFKPJL_01074 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKAFKPJL_01075 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
GKAFKPJL_01076 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
GKAFKPJL_01077 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GKAFKPJL_01078 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
GKAFKPJL_01079 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
GKAFKPJL_01080 2.36e-22 - - - S - - - YqzM-like protein
GKAFKPJL_01081 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
GKAFKPJL_01082 5.39e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
GKAFKPJL_01083 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
GKAFKPJL_01084 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKAFKPJL_01085 9.8e-179 yqeM - - Q - - - Methyltransferase
GKAFKPJL_01086 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKAFKPJL_01087 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
GKAFKPJL_01088 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKAFKPJL_01089 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
GKAFKPJL_01090 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKAFKPJL_01091 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GKAFKPJL_01092 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
GKAFKPJL_01094 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
GKAFKPJL_01095 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GKAFKPJL_01096 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
GKAFKPJL_01097 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
GKAFKPJL_01098 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
GKAFKPJL_01099 9.38e-171 - - - - - - - -
GKAFKPJL_01100 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
GKAFKPJL_01101 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_01102 0.0 - - - L ko:K06400 - ko00000 Recombinase
GKAFKPJL_01103 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
GKAFKPJL_01104 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKAFKPJL_01105 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GKAFKPJL_01106 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKAFKPJL_01107 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GKAFKPJL_01108 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
GKAFKPJL_01109 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
GKAFKPJL_01110 5.12e-112 ytrI - - - - - - -
GKAFKPJL_01111 1.15e-39 - - - - - - - -
GKAFKPJL_01112 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
GKAFKPJL_01113 2.15e-63 ytpI - - S - - - YtpI-like protein
GKAFKPJL_01114 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
GKAFKPJL_01115 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
GKAFKPJL_01116 1.58e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GKAFKPJL_01117 2.31e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
GKAFKPJL_01118 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_01119 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
GKAFKPJL_01120 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_01121 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKAFKPJL_01122 7.89e-154 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_01123 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_01124 6.27e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GKAFKPJL_01125 7.48e-194 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
GKAFKPJL_01126 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
GKAFKPJL_01127 1.37e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
GKAFKPJL_01128 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
GKAFKPJL_01129 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_01131 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
GKAFKPJL_01132 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKAFKPJL_01133 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
GKAFKPJL_01134 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKAFKPJL_01135 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
GKAFKPJL_01136 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKAFKPJL_01137 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
GKAFKPJL_01138 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
GKAFKPJL_01139 4.08e-112 yteJ - - S - - - RDD family
GKAFKPJL_01140 2.79e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
GKAFKPJL_01141 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKAFKPJL_01142 0.0 ytcJ - - S - - - amidohydrolase
GKAFKPJL_01143 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GKAFKPJL_01144 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
GKAFKPJL_01145 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKAFKPJL_01146 1.07e-263 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKAFKPJL_01147 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKAFKPJL_01148 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKAFKPJL_01149 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GKAFKPJL_01150 1.2e-141 yttP - - K - - - Transcriptional regulator
GKAFKPJL_01151 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
GKAFKPJL_01152 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
GKAFKPJL_01153 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKAFKPJL_01155 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKAFKPJL_01156 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GKAFKPJL_01157 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GKAFKPJL_01158 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
GKAFKPJL_01159 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
GKAFKPJL_01160 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GKAFKPJL_01161 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GKAFKPJL_01162 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
GKAFKPJL_01163 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GKAFKPJL_01164 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
GKAFKPJL_01165 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
GKAFKPJL_01166 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKAFKPJL_01167 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
GKAFKPJL_01168 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKAFKPJL_01169 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKAFKPJL_01170 2.06e-191 ytpQ - - S - - - Belongs to the UPF0354 family
GKAFKPJL_01171 3.17e-75 ytpP - - CO - - - Thioredoxin
GKAFKPJL_01172 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
GKAFKPJL_01173 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
GKAFKPJL_01174 1.17e-67 ytzB - - S - - - small secreted protein
GKAFKPJL_01175 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
GKAFKPJL_01176 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKAFKPJL_01177 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKAFKPJL_01178 9.51e-61 ytzH - - S - - - YtzH-like protein
GKAFKPJL_01179 3.02e-192 ytmP - - M - - - Phosphotransferase
GKAFKPJL_01180 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
GKAFKPJL_01181 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
GKAFKPJL_01182 4.04e-211 ytlQ - - - - - - -
GKAFKPJL_01183 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GKAFKPJL_01184 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKAFKPJL_01185 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
GKAFKPJL_01186 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
GKAFKPJL_01187 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
GKAFKPJL_01188 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKAFKPJL_01189 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
GKAFKPJL_01190 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
GKAFKPJL_01191 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_01192 4.04e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
GKAFKPJL_01193 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
GKAFKPJL_01194 2.14e-36 yteV - - S - - - Sporulation protein Cse60
GKAFKPJL_01195 3.81e-150 yteU - - S - - - Integral membrane protein
GKAFKPJL_01196 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
GKAFKPJL_01197 6.78e-94 yteS - - G - - - transport
GKAFKPJL_01198 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
GKAFKPJL_01199 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GKAFKPJL_01200 0.0 ytdP - - K - - - Transcriptional regulator
GKAFKPJL_01201 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GKAFKPJL_01202 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GKAFKPJL_01203 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
GKAFKPJL_01204 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKAFKPJL_01205 1.53e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GKAFKPJL_01206 2.2e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GKAFKPJL_01207 1.82e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GKAFKPJL_01208 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GKAFKPJL_01209 3.88e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GKAFKPJL_01210 1.13e-219 - - - S - - - Acetyl xylan esterase (AXE1)
GKAFKPJL_01211 1.31e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_01212 7.39e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKAFKPJL_01213 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_01214 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GKAFKPJL_01215 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GKAFKPJL_01216 7.08e-68 ytwF - - P - - - Sulfurtransferase
GKAFKPJL_01217 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
GKAFKPJL_01218 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
GKAFKPJL_01219 3.14e-182 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GKAFKPJL_01220 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
GKAFKPJL_01221 5.75e-78 yttA - - S - - - Pfam Transposase IS66
GKAFKPJL_01222 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
GKAFKPJL_01223 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_01224 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
GKAFKPJL_01225 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_01226 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKAFKPJL_01227 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_01228 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
GKAFKPJL_01229 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKAFKPJL_01230 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_01231 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
GKAFKPJL_01242 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKAFKPJL_01243 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GKAFKPJL_01244 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
GKAFKPJL_01245 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
GKAFKPJL_01246 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GKAFKPJL_01247 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
GKAFKPJL_01248 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
GKAFKPJL_01249 1.01e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
GKAFKPJL_01250 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
GKAFKPJL_01252 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
GKAFKPJL_01253 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
GKAFKPJL_01254 1.6e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKAFKPJL_01255 2.82e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
GKAFKPJL_01256 7.13e-168 yteA - - T - - - COG1734 DnaK suppressor protein
GKAFKPJL_01257 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GKAFKPJL_01258 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKAFKPJL_01259 1.29e-192 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GKAFKPJL_01260 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKAFKPJL_01261 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GKAFKPJL_01262 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GKAFKPJL_01263 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKAFKPJL_01264 6.12e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GKAFKPJL_01265 5.24e-296 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GKAFKPJL_01266 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GKAFKPJL_01267 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
GKAFKPJL_01268 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GKAFKPJL_01269 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GKAFKPJL_01270 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
GKAFKPJL_01271 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GKAFKPJL_01272 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKAFKPJL_01273 4.78e-95 ytkA - - S - - - YtkA-like
GKAFKPJL_01275 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
GKAFKPJL_01276 1.59e-81 ytkC - - S - - - Bacteriophage holin family
GKAFKPJL_01277 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
GKAFKPJL_01278 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GKAFKPJL_01279 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKAFKPJL_01280 1.26e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GKAFKPJL_01281 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GKAFKPJL_01282 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
GKAFKPJL_01283 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GKAFKPJL_01284 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKAFKPJL_01285 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
GKAFKPJL_01286 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_01287 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKAFKPJL_01288 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
GKAFKPJL_01289 2.29e-274 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
GKAFKPJL_01290 1.59e-135 ytqB - - J - - - Putative rRNA methylase
GKAFKPJL_01291 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
GKAFKPJL_01292 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
GKAFKPJL_01293 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
GKAFKPJL_01294 5.46e-74 ygzB - - S - - - UPF0295 protein
GKAFKPJL_01295 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
GKAFKPJL_01296 1.19e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
GKAFKPJL_01297 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GKAFKPJL_01298 1.87e-238 ygaE - - S - - - Membrane
GKAFKPJL_01299 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
GKAFKPJL_01300 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
GKAFKPJL_01301 2.01e-49 ygaB - - S - - - YgaB-like protein
GKAFKPJL_01302 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
GKAFKPJL_01303 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_01304 1.73e-48 yfhS - - - - - - -
GKAFKPJL_01305 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
GKAFKPJL_01306 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
GKAFKPJL_01307 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
GKAFKPJL_01308 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_01309 1.87e-216 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
GKAFKPJL_01310 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
GKAFKPJL_01311 2.32e-115 yfhK - - T - - - Bacterial SH3 domain homologues
GKAFKPJL_01312 8.95e-60 yfhJ - - S - - - WVELL protein
GKAFKPJL_01313 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
GKAFKPJL_01314 2.34e-266 yfhI - - EGP - - - -transporter
GKAFKPJL_01315 4.8e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
GKAFKPJL_01316 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
GKAFKPJL_01317 3.11e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
GKAFKPJL_01319 8.86e-35 yfhD - - S - - - YfhD-like protein
GKAFKPJL_01320 2.87e-138 yfhC - - C - - - nitroreductase
GKAFKPJL_01321 7.61e-215 yfhB - - S - - - PhzF family
GKAFKPJL_01322 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01323 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01324 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKAFKPJL_01325 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKAFKPJL_01326 2.11e-103 yfiV - - K - - - transcriptional
GKAFKPJL_01327 0.0 yfiU - - EGP - - - the major facilitator superfamily
GKAFKPJL_01328 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
GKAFKPJL_01329 5.4e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GKAFKPJL_01330 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKAFKPJL_01331 1.89e-128 padR - - K - - - transcriptional
GKAFKPJL_01332 1.1e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GKAFKPJL_01333 1.78e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
GKAFKPJL_01334 1.53e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_01335 3.51e-145 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
GKAFKPJL_01336 1.7e-272 baeS - - T - - - Histidine kinase
GKAFKPJL_01338 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
GKAFKPJL_01339 3.34e-83 yfiD3 - - S - - - DoxX
GKAFKPJL_01340 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKAFKPJL_01341 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKAFKPJL_01342 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
GKAFKPJL_01343 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_01344 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
GKAFKPJL_01345 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GKAFKPJL_01346 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
GKAFKPJL_01347 6.91e-241 yfjB - - - - - - -
GKAFKPJL_01348 3.83e-161 yfjC - - - - - - -
GKAFKPJL_01349 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
GKAFKPJL_01350 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
GKAFKPJL_01351 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
GKAFKPJL_01352 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
GKAFKPJL_01353 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKAFKPJL_01354 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKAFKPJL_01355 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKAFKPJL_01356 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKAFKPJL_01357 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
GKAFKPJL_01358 3.47e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKAFKPJL_01359 3.04e-59 - - - S - - - YfzA-like protein
GKAFKPJL_01360 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKAFKPJL_01361 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GKAFKPJL_01362 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
GKAFKPJL_01363 1.38e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GKAFKPJL_01364 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
GKAFKPJL_01365 3.26e-36 yfjT - - - - - - -
GKAFKPJL_01366 1.76e-283 yfkA - - S - - - YfkB-like domain
GKAFKPJL_01367 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
GKAFKPJL_01368 3.69e-189 yfkD - - S - - - YfkD-like protein
GKAFKPJL_01369 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
GKAFKPJL_01370 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_01371 1.64e-12 - - - - - - - -
GKAFKPJL_01372 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
GKAFKPJL_01373 1.03e-66 yfkI - - S - - - gas vesicle protein
GKAFKPJL_01374 8.37e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKAFKPJL_01375 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
GKAFKPJL_01376 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_01377 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GKAFKPJL_01378 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKAFKPJL_01379 5.27e-161 frp - - C - - - nitroreductase
GKAFKPJL_01380 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
GKAFKPJL_01381 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKAFKPJL_01382 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_01383 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
GKAFKPJL_01384 9.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
GKAFKPJL_01386 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
GKAFKPJL_01387 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
GKAFKPJL_01388 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
GKAFKPJL_01389 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKAFKPJL_01390 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GKAFKPJL_01391 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GKAFKPJL_01392 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
GKAFKPJL_01393 9.81e-27 yflI - - - - - - -
GKAFKPJL_01394 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
GKAFKPJL_01395 5.91e-158 yflK - - S - - - protein conserved in bacteria
GKAFKPJL_01396 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
GKAFKPJL_01397 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GKAFKPJL_01398 6.92e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
GKAFKPJL_01399 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKAFKPJL_01401 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
GKAFKPJL_01402 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
GKAFKPJL_01403 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKAFKPJL_01404 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
GKAFKPJL_01405 4.06e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
GKAFKPJL_01406 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
GKAFKPJL_01407 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
GKAFKPJL_01408 7.58e-217 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GKAFKPJL_01409 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01410 4.94e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01411 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GKAFKPJL_01412 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
GKAFKPJL_01413 1.72e-268 - - - G - - - Major Facilitator Superfamily
GKAFKPJL_01414 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
GKAFKPJL_01415 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
GKAFKPJL_01416 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
GKAFKPJL_01417 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKAFKPJL_01418 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
GKAFKPJL_01419 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
GKAFKPJL_01420 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
GKAFKPJL_01421 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKAFKPJL_01422 5.14e-161 yfmS - - NT - - - chemotaxis protein
GKAFKPJL_01423 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKAFKPJL_01424 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
GKAFKPJL_01425 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKAFKPJL_01426 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_01427 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
GKAFKPJL_01428 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
GKAFKPJL_01429 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
GKAFKPJL_01430 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
GKAFKPJL_01431 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
GKAFKPJL_01432 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
GKAFKPJL_01433 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GKAFKPJL_01434 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
GKAFKPJL_01435 2.57e-171 - - - M - - - Membrane
GKAFKPJL_01436 1.78e-265 yetM - - CH - - - FAD binding domain
GKAFKPJL_01437 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_01438 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
GKAFKPJL_01439 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
GKAFKPJL_01440 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKAFKPJL_01441 9.79e-45 - - - - - - - -
GKAFKPJL_01442 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_01443 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
GKAFKPJL_01444 6.06e-156 yetF - - S - - - membrane
GKAFKPJL_01445 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
GKAFKPJL_01446 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_01447 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
GKAFKPJL_01448 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKAFKPJL_01449 0.0 yetA - - - - - - -
GKAFKPJL_01450 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
GKAFKPJL_01451 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKAFKPJL_01452 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GKAFKPJL_01453 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
GKAFKPJL_01454 7.78e-143 - - - S - - - Protein of unknown function, DUF624
GKAFKPJL_01455 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
GKAFKPJL_01456 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKAFKPJL_01457 0.0 yesS - - K - - - Transcriptional regulator
GKAFKPJL_01458 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
GKAFKPJL_01459 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_01460 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_01461 1.44e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
GKAFKPJL_01462 2.31e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
GKAFKPJL_01463 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_01464 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
GKAFKPJL_01465 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
GKAFKPJL_01466 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
GKAFKPJL_01467 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
GKAFKPJL_01468 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
GKAFKPJL_01469 1.23e-195 yesF - - GM - - - NAD(P)H-binding
GKAFKPJL_01470 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
GKAFKPJL_01471 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_01473 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
GKAFKPJL_01475 1.42e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
GKAFKPJL_01476 2.32e-235 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
GKAFKPJL_01477 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
GKAFKPJL_01478 1.09e-73 - - - S - - - Protein of unknown function, DUF600
GKAFKPJL_01479 8.48e-105 - - - S - - - Protein of unknown function, DUF600
GKAFKPJL_01481 4.5e-41 - - - S - - - Colicin immunity protein / pyocin immunity protein
GKAFKPJL_01483 3.95e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKAFKPJL_01486 6.7e-95 - - - V - - - Type I restriction modification DNA specificity domain
GKAFKPJL_01487 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system methyltransferase subunit()
GKAFKPJL_01488 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKAFKPJL_01489 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GKAFKPJL_01490 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GKAFKPJL_01491 2.43e-189 yerO - - K - - - Transcriptional regulator
GKAFKPJL_01492 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKAFKPJL_01493 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKAFKPJL_01494 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKAFKPJL_01495 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKAFKPJL_01496 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
GKAFKPJL_01497 1.73e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
GKAFKPJL_01498 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
GKAFKPJL_01499 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKAFKPJL_01500 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
GKAFKPJL_01501 1.72e-46 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GKAFKPJL_01504 1.63e-232 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GKAFKPJL_01505 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
GKAFKPJL_01506 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
GKAFKPJL_01507 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GKAFKPJL_01508 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKAFKPJL_01509 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
GKAFKPJL_01510 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GKAFKPJL_01511 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKAFKPJL_01512 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GKAFKPJL_01513 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKAFKPJL_01514 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
GKAFKPJL_01515 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKAFKPJL_01516 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKAFKPJL_01517 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKAFKPJL_01518 8.99e-181 - - - L - - - Belongs to the 'phage' integrase family
GKAFKPJL_01519 1.55e-60 xkdA - - E - - - IrrE N-terminal-like domain
GKAFKPJL_01521 3.4e-28 - - - K - - - transcriptional
GKAFKPJL_01522 5.23e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
GKAFKPJL_01523 9.71e-48 - - - - - - - -
GKAFKPJL_01524 4.03e-55 - - - S - - - DNA binding
GKAFKPJL_01525 4.76e-105 - - - - - - - -
GKAFKPJL_01531 1.33e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
GKAFKPJL_01532 1.79e-171 recT - - L ko:K07455 - ko00000,ko03400 RecT family
GKAFKPJL_01533 2.85e-97 yqaL - - L - - - DnaD domain protein
GKAFKPJL_01534 9.92e-101 yqaM - - L - - - IstB-like ATP binding protein
GKAFKPJL_01536 9.34e-18 - - - S - - - YopX protein
GKAFKPJL_01537 6.38e-71 - - - S - - - Protein of unknown function (DUF1064)
GKAFKPJL_01539 8.51e-26 yqaO - - S - - - Phage-like element PBSX protein XtrA
GKAFKPJL_01541 6.31e-98 - - - - - - - -
GKAFKPJL_01543 1.03e-92 - - - - - - - -
GKAFKPJL_01544 4.55e-77 - - - - - - - -
GKAFKPJL_01545 0.000179 - - - S - - - YopX protein
GKAFKPJL_01553 2.93e-102 - - - L - - - Transposase
GKAFKPJL_01555 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_01556 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_01557 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GKAFKPJL_01558 5.75e-242 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
GKAFKPJL_01559 9.8e-313 yoeA - - V - - - MATE efflux family protein
GKAFKPJL_01560 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
GKAFKPJL_01562 1.14e-124 - - - L - - - Integrase
GKAFKPJL_01563 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
GKAFKPJL_01564 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GKAFKPJL_01565 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_01566 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GKAFKPJL_01567 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GKAFKPJL_01568 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
GKAFKPJL_01569 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_01570 1.91e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKAFKPJL_01571 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKAFKPJL_01572 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GKAFKPJL_01573 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_01574 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
GKAFKPJL_01575 5.79e-171 yoxB - - - - - - -
GKAFKPJL_01576 7.43e-119 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKAFKPJL_01577 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
GKAFKPJL_01578 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
GKAFKPJL_01579 9.45e-67 - - - K - - - Helix-turn-helix domain
GKAFKPJL_01580 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
GKAFKPJL_01581 3.12e-61 - - - - - - - -
GKAFKPJL_01582 1.99e-120 ybcF - - P - - - carbonic anhydrase
GKAFKPJL_01583 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
GKAFKPJL_01584 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GKAFKPJL_01585 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKAFKPJL_01586 1.03e-153 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
GKAFKPJL_01587 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GKAFKPJL_01588 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKAFKPJL_01589 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKAFKPJL_01590 3.41e-291 ybbR - - S - - - protein conserved in bacteria
GKAFKPJL_01591 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKAFKPJL_01592 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GKAFKPJL_01593 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_01599 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
GKAFKPJL_01600 1.81e-113 ybbJ - - J - - - acetyltransferase
GKAFKPJL_01601 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKAFKPJL_01602 3.01e-191 ybbH - - K - - - transcriptional
GKAFKPJL_01603 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_01604 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
GKAFKPJL_01605 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
GKAFKPJL_01606 8.14e-303 ybbC - - S - - - protein conserved in bacteria
GKAFKPJL_01607 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
GKAFKPJL_01608 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
GKAFKPJL_01609 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01610 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_01611 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
GKAFKPJL_01612 1.26e-201 ybaS - - S - - - Na -dependent transporter
GKAFKPJL_01614 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GKAFKPJL_01615 1.3e-67 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKAFKPJL_01616 5.4e-80 - - - - - - - -
GKAFKPJL_01618 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GKAFKPJL_01619 8.36e-89 - - - S - - - Bacteriophage holin family
GKAFKPJL_01620 2.45e-213 xepA - - - - - - -
GKAFKPJL_01621 9.34e-33 - - - - - - - -
GKAFKPJL_01622 1.01e-73 xkdW - - S - - - XkdW protein
GKAFKPJL_01623 2.91e-283 - - - - - - - -
GKAFKPJL_01624 3e-54 - - - - - - - -
GKAFKPJL_01625 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
GKAFKPJL_01626 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GKAFKPJL_01627 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
GKAFKPJL_01628 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
GKAFKPJL_01629 1.02e-231 xkdQ - - G - - - NLP P60 protein
GKAFKPJL_01630 6.56e-156 xkdP - - S - - - Lysin motif
GKAFKPJL_01631 0.0 xkdO - - L - - - Transglycosylase SLT domain
GKAFKPJL_01632 1.27e-89 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
GKAFKPJL_01633 1.21e-98 xkdM - - S - - - Phage tail tube protein
GKAFKPJL_01634 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
GKAFKPJL_01635 4.2e-35 - - - - - - - -
GKAFKPJL_01636 8.94e-100 yqbJ - - - - - - -
GKAFKPJL_01637 7.57e-114 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKAFKPJL_01638 2.38e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
GKAFKPJL_01639 2.89e-87 - - - S - - - Protein of unknown function (DUF3199)
GKAFKPJL_01640 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
GKAFKPJL_01641 4.37e-214 xkdG - - S - - - Phage capsid family
GKAFKPJL_01642 3.46e-157 yqbD - - L - - - Putative phage serine protease XkdF
GKAFKPJL_01644 1.37e-182 - - - S - - - Phage Mu protein F like protein
GKAFKPJL_01645 0.0 yqbA - - S - - - portal protein
GKAFKPJL_01646 3.86e-316 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
GKAFKPJL_01647 5.44e-147 yqaS - - L - - - DNA packaging
GKAFKPJL_01650 1.71e-100 yqaQ - - L - - - Transposase
GKAFKPJL_01653 1.24e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
GKAFKPJL_01654 5.21e-93 rusA - - L - - - Endodeoxyribonuclease RusA
GKAFKPJL_01656 2.72e-211 yqaM - - L - - - IstB-like ATP binding protein
GKAFKPJL_01657 8.41e-153 yqaL - - L - - - DnaD domain protein
GKAFKPJL_01658 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
GKAFKPJL_01659 3.76e-219 yqaJ - - L - - - YqaJ-like viral recombinase domain
GKAFKPJL_01663 1.04e-133 - - - - - - - -
GKAFKPJL_01665 1.02e-24 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
GKAFKPJL_01666 1.88e-42 - - - K - - - sequence-specific DNA binding
GKAFKPJL_01667 1.6e-187 - - - S - - - Bacterial EndoU nuclease
GKAFKPJL_01668 1.93e-53 - - - - - - - -
GKAFKPJL_01672 5.55e-54 rnhA - - L ko:K06993 - ko00000 Caulimovirus viroplasmin
GKAFKPJL_01673 7.9e-37 - - - K - - - Helix-turn-helix domain
GKAFKPJL_01675 7.52e-55 - - - S - - - protein domain associated with
GKAFKPJL_01676 3.42e-139 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GKAFKPJL_01677 1.58e-41 xhlB - - S - - - SPP1 phage holin
GKAFKPJL_01678 7.72e-37 xhlA - - S - - - Haemolysin XhlA
GKAFKPJL_01683 1.27e-206 - - - L - - - Phage minor structural protein
GKAFKPJL_01684 5.17e-35 - - - S - - - Phage tail protein
GKAFKPJL_01685 3.37e-146 - - - D - - - minor tail protein
GKAFKPJL_01686 8.86e-46 - - - S - - - Bacteriophage Gp15 protein
GKAFKPJL_01688 3.38e-53 - - - N - - - Belongs to the glycosyl hydrolase family 6
GKAFKPJL_01690 7.09e-28 - - - S - - - Minor capsid protein
GKAFKPJL_01692 2.32e-27 - - - - - - - -
GKAFKPJL_01693 3.89e-10 chiA - - G - - - Belongs to the glycosyl hydrolase 18 family
GKAFKPJL_01694 1.16e-123 - - - - - - - -
GKAFKPJL_01695 9.91e-25 - - - - - - - -
GKAFKPJL_01696 4.03e-116 - - - M - - - Phage minor capsid protein 2
GKAFKPJL_01697 1.16e-210 - - - S - - - portal protein
GKAFKPJL_01698 3.73e-272 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
GKAFKPJL_01699 4.06e-35 yqaS - - L - - - DNA packaging
GKAFKPJL_01700 5.43e-52 ykoA - - - - - - -
GKAFKPJL_01701 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GKAFKPJL_01702 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKAFKPJL_01703 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
GKAFKPJL_01704 1.09e-18 - - - S - - - Uncharacterized protein YkpC
GKAFKPJL_01705 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
GKAFKPJL_01706 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
GKAFKPJL_01707 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GKAFKPJL_01708 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
GKAFKPJL_01709 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GKAFKPJL_01710 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GKAFKPJL_01711 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKAFKPJL_01712 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
GKAFKPJL_01713 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
GKAFKPJL_01714 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKAFKPJL_01715 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
GKAFKPJL_01716 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
GKAFKPJL_01717 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GKAFKPJL_01718 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKAFKPJL_01719 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKAFKPJL_01720 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GKAFKPJL_01721 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
GKAFKPJL_01722 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
GKAFKPJL_01723 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
GKAFKPJL_01724 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
GKAFKPJL_01725 4.48e-35 ykzI - - - - - - -
GKAFKPJL_01726 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
GKAFKPJL_01727 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
GKAFKPJL_01728 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GKAFKPJL_01729 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
GKAFKPJL_01730 0.0 ylaA - - - - - - -
GKAFKPJL_01731 1.44e-56 ylaB - - - - - - -
GKAFKPJL_01732 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_01734 1.74e-57 ylaE - - - - - - -
GKAFKPJL_01735 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
GKAFKPJL_01736 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
GKAFKPJL_01737 4.4e-63 ylaH - - S - - - YlaH-like protein
GKAFKPJL_01738 8.92e-44 ylaI - - S - - - protein conserved in bacteria
GKAFKPJL_01739 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKAFKPJL_01740 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
GKAFKPJL_01741 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GKAFKPJL_01742 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKAFKPJL_01743 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
GKAFKPJL_01744 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKAFKPJL_01745 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GKAFKPJL_01746 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GKAFKPJL_01747 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GKAFKPJL_01748 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GKAFKPJL_01749 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKAFKPJL_01750 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GKAFKPJL_01751 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GKAFKPJL_01752 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
GKAFKPJL_01753 1.61e-81 ylbA - - S - - - YugN-like family
GKAFKPJL_01754 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
GKAFKPJL_01755 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
GKAFKPJL_01756 3.24e-89 ylbD - - S - - - Putative coat protein
GKAFKPJL_01757 1.73e-48 ylbE - - S - - - YlbE-like protein
GKAFKPJL_01758 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
GKAFKPJL_01759 8.8e-52 ylbG - - S - - - UPF0298 protein
GKAFKPJL_01760 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
GKAFKPJL_01761 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKAFKPJL_01762 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
GKAFKPJL_01763 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
GKAFKPJL_01764 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
GKAFKPJL_01765 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
GKAFKPJL_01767 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
GKAFKPJL_01768 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
GKAFKPJL_01769 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GKAFKPJL_01770 1.33e-115 ylbP - - K - - - n-acetyltransferase
GKAFKPJL_01771 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GKAFKPJL_01772 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GKAFKPJL_01773 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
GKAFKPJL_01774 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKAFKPJL_01775 3.42e-68 ftsL - - D - - - Essential cell division protein
GKAFKPJL_01776 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKAFKPJL_01777 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
GKAFKPJL_01778 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKAFKPJL_01779 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKAFKPJL_01780 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKAFKPJL_01781 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
GKAFKPJL_01782 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKAFKPJL_01783 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
GKAFKPJL_01784 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKAFKPJL_01785 4.5e-142 ylxW - - S - - - protein conserved in bacteria
GKAFKPJL_01786 1.03e-123 ylxX - - S - - - protein conserved in bacteria
GKAFKPJL_01787 5.37e-76 sbp - - S - - - small basic protein
GKAFKPJL_01788 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKAFKPJL_01789 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKAFKPJL_01790 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
GKAFKPJL_01792 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GKAFKPJL_01793 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_01794 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_01795 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GKAFKPJL_01796 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
GKAFKPJL_01797 3.58e-51 ylmC - - S - - - sporulation protein
GKAFKPJL_01798 7.23e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
GKAFKPJL_01799 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKAFKPJL_01800 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GKAFKPJL_01801 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
GKAFKPJL_01802 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
GKAFKPJL_01803 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
GKAFKPJL_01804 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKAFKPJL_01805 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
GKAFKPJL_01806 5.47e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKAFKPJL_01807 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
GKAFKPJL_01808 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKAFKPJL_01809 3.71e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
GKAFKPJL_01810 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
GKAFKPJL_01811 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKAFKPJL_01812 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
GKAFKPJL_01813 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
GKAFKPJL_01814 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GKAFKPJL_01815 6.05e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKAFKPJL_01816 8.94e-162 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKAFKPJL_01817 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKAFKPJL_01819 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
GKAFKPJL_01820 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
GKAFKPJL_01821 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
GKAFKPJL_01822 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
GKAFKPJL_01823 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GKAFKPJL_01824 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
GKAFKPJL_01825 6.53e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
GKAFKPJL_01826 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
GKAFKPJL_01827 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
GKAFKPJL_01828 8.41e-202 yloC - - S - - - stress-induced protein
GKAFKPJL_01829 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
GKAFKPJL_01830 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
GKAFKPJL_01831 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GKAFKPJL_01832 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKAFKPJL_01833 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKAFKPJL_01834 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKAFKPJL_01835 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKAFKPJL_01836 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKAFKPJL_01837 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKAFKPJL_01838 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
GKAFKPJL_01839 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKAFKPJL_01840 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKAFKPJL_01841 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
GKAFKPJL_01842 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
GKAFKPJL_01843 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
GKAFKPJL_01844 3.65e-78 yloU - - S - - - protein conserved in bacteria
GKAFKPJL_01845 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
GKAFKPJL_01846 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GKAFKPJL_01847 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
GKAFKPJL_01848 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKAFKPJL_01849 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GKAFKPJL_01850 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKAFKPJL_01851 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
GKAFKPJL_01852 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
GKAFKPJL_01853 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKAFKPJL_01854 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKAFKPJL_01855 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
GKAFKPJL_01856 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKAFKPJL_01857 1.67e-114 - - - - - - - -
GKAFKPJL_01858 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKAFKPJL_01859 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKAFKPJL_01860 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
GKAFKPJL_01861 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
GKAFKPJL_01862 3.41e-80 ylqD - - S - - - YlqD protein
GKAFKPJL_01863 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKAFKPJL_01864 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
GKAFKPJL_01865 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKAFKPJL_01866 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKAFKPJL_01867 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKAFKPJL_01868 0.0 ylqG - - - - - - -
GKAFKPJL_01869 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
GKAFKPJL_01870 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GKAFKPJL_01871 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GKAFKPJL_01872 7.62e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
GKAFKPJL_01873 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKAFKPJL_01874 3.67e-312 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKAFKPJL_01875 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
GKAFKPJL_01877 4.25e-25 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
GKAFKPJL_01878 1.4e-86 - - - S - - - regulation of transcription, DNA-dependent
GKAFKPJL_01879 1.82e-31 - - - S - - - FRG
GKAFKPJL_01880 9.88e-66 - - - M - - - ArpU family transcriptional regulator
GKAFKPJL_01883 3.5e-30 - - - - - - - -
GKAFKPJL_01884 9.44e-127 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
GKAFKPJL_01885 4.61e-47 - - - L - - - Arm DNA-binding domain
GKAFKPJL_01886 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
GKAFKPJL_01887 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
GKAFKPJL_01888 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GKAFKPJL_01889 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKAFKPJL_01890 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
GKAFKPJL_01891 3.32e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKAFKPJL_01892 2.24e-141 - - - - - - - -
GKAFKPJL_01893 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKAFKPJL_01894 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKAFKPJL_01895 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
GKAFKPJL_01896 1.2e-30 ymzA - - - - - - -
GKAFKPJL_01897 1.63e-31 - - - - - - - -
GKAFKPJL_01898 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GKAFKPJL_01899 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKAFKPJL_01900 5.41e-76 ymaF - - S - - - YmaF family
GKAFKPJL_01902 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GKAFKPJL_01903 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
GKAFKPJL_01904 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
GKAFKPJL_01905 3.96e-163 ymaC - - S - - - Replication protein
GKAFKPJL_01907 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
GKAFKPJL_01908 7.65e-207 - - - S - - - Metallo-beta-lactamase superfamily
GKAFKPJL_01909 9.39e-80 ymzB - - - - - - -
GKAFKPJL_01910 2.79e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKAFKPJL_01911 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
GKAFKPJL_01912 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKAFKPJL_01913 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
GKAFKPJL_01915 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_01916 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
GKAFKPJL_01917 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
GKAFKPJL_01919 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GKAFKPJL_01920 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKAFKPJL_01921 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
GKAFKPJL_01922 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
GKAFKPJL_01924 8.34e-180 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
GKAFKPJL_01925 7.4e-193 ybdN - - - - - - -
GKAFKPJL_01926 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
GKAFKPJL_01927 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_01928 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
GKAFKPJL_01929 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
GKAFKPJL_01930 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
GKAFKPJL_01931 8.23e-309 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
GKAFKPJL_01932 1.11e-54 ybyB - - - - - - -
GKAFKPJL_01933 0.0 ybeC - - E - - - amino acid
GKAFKPJL_01934 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
GKAFKPJL_01935 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
GKAFKPJL_01936 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
GKAFKPJL_01937 1.59e-215 ybfA - - K - - - FR47-like protein
GKAFKPJL_01938 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_01940 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
GKAFKPJL_01941 5.27e-208 ybfH - - EG - - - EamA-like transporter family
GKAFKPJL_01942 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
GKAFKPJL_01943 1.95e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKAFKPJL_01944 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
GKAFKPJL_01946 1.37e-214 - - - S - - - Alpha/beta hydrolase family
GKAFKPJL_01947 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKAFKPJL_01948 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
GKAFKPJL_01949 1.45e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GKAFKPJL_01950 1.58e-59 ybfN - - - - - - -
GKAFKPJL_01951 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
GKAFKPJL_01952 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GKAFKPJL_01953 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_01954 1.23e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKAFKPJL_01955 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GKAFKPJL_01957 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GKAFKPJL_01958 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKAFKPJL_01959 9.76e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
GKAFKPJL_01960 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GKAFKPJL_01961 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
GKAFKPJL_01962 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_01963 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
GKAFKPJL_01964 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
GKAFKPJL_01965 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKAFKPJL_01966 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_01967 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKAFKPJL_01968 4.63e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
GKAFKPJL_01969 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GKAFKPJL_01970 2.47e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
GKAFKPJL_01971 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
GKAFKPJL_01972 7.31e-218 eamA1 - - EG - - - spore germination
GKAFKPJL_01973 3.71e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_01974 6.21e-214 ycbM - - T - - - Histidine kinase
GKAFKPJL_01975 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_01976 2.87e-148 - - - S - - - ABC-2 family transporter protein
GKAFKPJL_01977 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
GKAFKPJL_01978 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
GKAFKPJL_01979 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
GKAFKPJL_01980 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
GKAFKPJL_01981 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GKAFKPJL_01982 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKAFKPJL_01983 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GKAFKPJL_01984 4.86e-259 ycbU - - E - - - Selenocysteine lyase
GKAFKPJL_01985 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
GKAFKPJL_01986 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GKAFKPJL_01987 1.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GKAFKPJL_01988 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
GKAFKPJL_01989 4.32e-78 - - - S - - - RDD family
GKAFKPJL_01990 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
GKAFKPJL_01991 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
GKAFKPJL_01992 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
GKAFKPJL_01993 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
GKAFKPJL_01994 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKAFKPJL_01995 6.81e-222 yccK - - C - - - Aldo keto reductase
GKAFKPJL_01996 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
GKAFKPJL_01997 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_01998 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_01999 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
GKAFKPJL_02000 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
GKAFKPJL_02001 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_02002 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKAFKPJL_02003 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
GKAFKPJL_02004 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GKAFKPJL_02005 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GKAFKPJL_02006 4.01e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_02007 1.78e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
GKAFKPJL_02008 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GKAFKPJL_02009 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
GKAFKPJL_02010 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
GKAFKPJL_02011 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
GKAFKPJL_02012 2.96e-245 yceH - - P - - - Belongs to the TelA family
GKAFKPJL_02013 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
GKAFKPJL_02014 2.25e-265 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
GKAFKPJL_02015 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
GKAFKPJL_02016 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
GKAFKPJL_02017 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GKAFKPJL_02018 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
GKAFKPJL_02019 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
GKAFKPJL_02020 0.0 ycgA - - S - - - Membrane
GKAFKPJL_02021 2.72e-105 ycgB - - - - - - -
GKAFKPJL_02022 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
GKAFKPJL_02023 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
GKAFKPJL_02024 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKAFKPJL_02025 0.0 mdr - - EGP - - - the major facilitator superfamily
GKAFKPJL_02026 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_02027 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
GKAFKPJL_02028 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
GKAFKPJL_02029 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_02030 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
GKAFKPJL_02031 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKAFKPJL_02032 3.09e-139 tmrB - - S - - - AAA domain
GKAFKPJL_02034 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKAFKPJL_02035 7.18e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
GKAFKPJL_02036 1.88e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
GKAFKPJL_02037 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
GKAFKPJL_02038 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
GKAFKPJL_02039 2.1e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GKAFKPJL_02040 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GKAFKPJL_02041 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKAFKPJL_02042 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
GKAFKPJL_02043 1.28e-193 ycgQ - - S ko:K08986 - ko00000 membrane
GKAFKPJL_02044 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
GKAFKPJL_02045 3.44e-202 ycgS - - I - - - alpha/beta hydrolase fold
GKAFKPJL_02046 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
GKAFKPJL_02047 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
GKAFKPJL_02048 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
GKAFKPJL_02049 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GKAFKPJL_02050 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKAFKPJL_02051 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
GKAFKPJL_02052 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GKAFKPJL_02053 1.22e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
GKAFKPJL_02054 9.22e-137 - - - M - - - ErfK YbiS YcfS YnhG
GKAFKPJL_02055 6.78e-291 yciC - - S - - - GTPases (G3E family)
GKAFKPJL_02056 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKAFKPJL_02057 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GKAFKPJL_02059 5.95e-101 yckC - - S - - - membrane
GKAFKPJL_02060 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
GKAFKPJL_02061 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKAFKPJL_02062 4.78e-91 nin - - S - - - Competence protein J (ComJ)
GKAFKPJL_02063 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
GKAFKPJL_02064 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02065 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
GKAFKPJL_02066 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
GKAFKPJL_02067 6.05e-86 hxlR - - K - - - transcriptional
GKAFKPJL_02068 1.4e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
GKAFKPJL_02069 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02070 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
GKAFKPJL_02071 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GKAFKPJL_02072 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GKAFKPJL_02074 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKAFKPJL_02075 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
GKAFKPJL_02076 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKAFKPJL_02077 1.27e-59 ysdA - - S - - - Membrane
GKAFKPJL_02078 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
GKAFKPJL_02079 2.93e-260 ysdC - - G - - - COG1363 Cellulase M and related proteins
GKAFKPJL_02080 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GKAFKPJL_02081 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
GKAFKPJL_02082 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
GKAFKPJL_02083 1.99e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GKAFKPJL_02084 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
GKAFKPJL_02085 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GKAFKPJL_02086 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GKAFKPJL_02087 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
GKAFKPJL_02088 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
GKAFKPJL_02089 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
GKAFKPJL_02090 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
GKAFKPJL_02091 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
GKAFKPJL_02092 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
GKAFKPJL_02093 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
GKAFKPJL_02094 4.34e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
GKAFKPJL_02095 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
GKAFKPJL_02096 8.97e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKAFKPJL_02097 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKAFKPJL_02098 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKAFKPJL_02099 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKAFKPJL_02100 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GKAFKPJL_02101 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
GKAFKPJL_02102 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
GKAFKPJL_02103 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKAFKPJL_02104 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
GKAFKPJL_02105 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GKAFKPJL_02106 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_02107 1.27e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
GKAFKPJL_02108 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
GKAFKPJL_02109 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
GKAFKPJL_02111 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
GKAFKPJL_02112 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
GKAFKPJL_02113 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKAFKPJL_02114 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKAFKPJL_02115 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
GKAFKPJL_02116 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
GKAFKPJL_02117 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GKAFKPJL_02118 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
GKAFKPJL_02119 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
GKAFKPJL_02120 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_02121 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_02122 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKAFKPJL_02123 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
GKAFKPJL_02124 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GKAFKPJL_02125 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKAFKPJL_02126 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
GKAFKPJL_02128 1.12e-163 ysnF - - S - - - protein conserved in bacteria
GKAFKPJL_02129 1.71e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
GKAFKPJL_02131 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GKAFKPJL_02132 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
GKAFKPJL_02133 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GKAFKPJL_02134 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKAFKPJL_02135 4.3e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GKAFKPJL_02136 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKAFKPJL_02137 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKAFKPJL_02138 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
GKAFKPJL_02139 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKAFKPJL_02140 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKAFKPJL_02141 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
GKAFKPJL_02142 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKAFKPJL_02143 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
GKAFKPJL_02144 8.23e-117 ysxD - - - - - - -
GKAFKPJL_02145 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GKAFKPJL_02146 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
GKAFKPJL_02147 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GKAFKPJL_02148 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GKAFKPJL_02149 1.51e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
GKAFKPJL_02150 1.05e-313 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
GKAFKPJL_02151 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
GKAFKPJL_02152 1.96e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GKAFKPJL_02153 1.53e-35 - - - - - - - -
GKAFKPJL_02154 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKAFKPJL_02155 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
GKAFKPJL_02156 4.61e-107 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GKAFKPJL_02157 3.36e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
GKAFKPJL_02158 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
GKAFKPJL_02159 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
GKAFKPJL_02160 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
GKAFKPJL_02161 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
GKAFKPJL_02162 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
GKAFKPJL_02163 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GKAFKPJL_02164 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
GKAFKPJL_02165 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GKAFKPJL_02166 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
GKAFKPJL_02167 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
GKAFKPJL_02168 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
GKAFKPJL_02169 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
GKAFKPJL_02170 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
GKAFKPJL_02171 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKAFKPJL_02172 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
GKAFKPJL_02173 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
GKAFKPJL_02174 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
GKAFKPJL_02175 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKAFKPJL_02176 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
GKAFKPJL_02177 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
GKAFKPJL_02178 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GKAFKPJL_02179 1.15e-215 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
GKAFKPJL_02180 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKAFKPJL_02181 1.01e-163 yebC - - K - - - transcriptional regulatory protein
GKAFKPJL_02182 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
GKAFKPJL_02184 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
GKAFKPJL_02186 2.32e-152 yrzF - - T - - - serine threonine protein kinase
GKAFKPJL_02187 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
GKAFKPJL_02188 0.0 csbX - - EGP - - - the major facilitator superfamily
GKAFKPJL_02189 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
GKAFKPJL_02190 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKAFKPJL_02191 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKAFKPJL_02192 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
GKAFKPJL_02193 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKAFKPJL_02194 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKAFKPJL_02195 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
GKAFKPJL_02196 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
GKAFKPJL_02197 5.83e-143 yrbG - - S - - - membrane
GKAFKPJL_02198 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_02199 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
GKAFKPJL_02200 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GKAFKPJL_02201 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
GKAFKPJL_02202 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
GKAFKPJL_02203 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
GKAFKPJL_02204 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKAFKPJL_02205 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKAFKPJL_02206 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKAFKPJL_02207 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
GKAFKPJL_02209 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
GKAFKPJL_02210 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GKAFKPJL_02211 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GKAFKPJL_02212 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GKAFKPJL_02213 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_02214 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
GKAFKPJL_02215 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKAFKPJL_02216 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
GKAFKPJL_02217 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKAFKPJL_02218 3.39e-106 yrrD - - S - - - protein conserved in bacteria
GKAFKPJL_02219 8.4e-42 yrzR - - - - - - -
GKAFKPJL_02220 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
GKAFKPJL_02221 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_02222 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_02223 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKAFKPJL_02224 1.55e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
GKAFKPJL_02225 8.81e-242 yrrI - - S - - - AI-2E family transporter
GKAFKPJL_02226 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKAFKPJL_02227 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
GKAFKPJL_02228 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKAFKPJL_02229 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
GKAFKPJL_02230 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKAFKPJL_02231 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
GKAFKPJL_02232 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
GKAFKPJL_02233 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
GKAFKPJL_02234 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
GKAFKPJL_02235 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKAFKPJL_02236 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
GKAFKPJL_02237 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
GKAFKPJL_02238 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
GKAFKPJL_02239 8.44e-154 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
GKAFKPJL_02240 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKAFKPJL_02241 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
GKAFKPJL_02242 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKAFKPJL_02243 6.93e-49 yrhC - - S - - - YrhC-like protein
GKAFKPJL_02244 4.97e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
GKAFKPJL_02245 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GKAFKPJL_02246 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
GKAFKPJL_02247 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
GKAFKPJL_02249 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
GKAFKPJL_02250 7.42e-125 yrhH - - Q - - - methyltransferase
GKAFKPJL_02251 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
GKAFKPJL_02252 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
GKAFKPJL_02253 6.3e-61 yrhK - - S - - - YrhK-like protein
GKAFKPJL_02254 0.0 oatA - - I - - - Acyltransferase family
GKAFKPJL_02255 2.12e-192 rsiV - - S - - - Protein of unknown function (DUF3298)
GKAFKPJL_02256 1.65e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_02257 2.81e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
GKAFKPJL_02258 9.6e-114 yrhP - - E - - - LysE type translocator
GKAFKPJL_02259 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_02260 0.0 levR - - K - - - PTS system fructose IIA component
GKAFKPJL_02261 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
GKAFKPJL_02262 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
GKAFKPJL_02263 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
GKAFKPJL_02264 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
GKAFKPJL_02265 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GKAFKPJL_02266 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
GKAFKPJL_02267 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
GKAFKPJL_02268 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
GKAFKPJL_02269 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
GKAFKPJL_02270 6.11e-36 yraE - - - ko:K06440 - ko00000 -
GKAFKPJL_02271 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GKAFKPJL_02272 9.61e-84 yraF - - M - - - Spore coat protein
GKAFKPJL_02273 1.2e-49 yraG - - - ko:K06440 - ko00000 -
GKAFKPJL_02274 5.45e-86 - - - E - - - Glyoxalase-like domain
GKAFKPJL_02276 2.92e-81 - - - T - - - sh3 domain protein
GKAFKPJL_02277 6.61e-80 - - - T - - - sh3 domain protein
GKAFKPJL_02278 1.51e-190 - - - S - - - Alpha beta hydrolase
GKAFKPJL_02279 6.94e-54 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_02280 3.65e-192 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GKAFKPJL_02281 1.15e-260 yraM - - S - - - PrpF protein
GKAFKPJL_02282 7e-209 yraN - - K - - - Transcriptional regulator
GKAFKPJL_02283 5.08e-284 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKAFKPJL_02284 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
GKAFKPJL_02285 1.39e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_02286 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
GKAFKPJL_02287 9.71e-31 epsA - - I - - - Passenger-associated-transport-repeat
GKAFKPJL_02288 1.62e-63 - - - S - - - YjbR
GKAFKPJL_02289 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
GKAFKPJL_02290 3.1e-126 - - - S - - - Flavin reductase like domain
GKAFKPJL_02291 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
GKAFKPJL_02292 8.71e-194 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
GKAFKPJL_02293 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_02294 1.67e-267 - - - P - - - Major Facilitator Superfamily
GKAFKPJL_02296 1.16e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
GKAFKPJL_02297 4.62e-160 yrpD - - S - - - Domain of unknown function, YrpD
GKAFKPJL_02298 1.39e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
GKAFKPJL_02299 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GKAFKPJL_02300 5.77e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
GKAFKPJL_02301 1.17e-117 yrdA - - S - - - DinB family
GKAFKPJL_02302 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
GKAFKPJL_02303 1.01e-128 yrdC - - Q - - - Isochorismatase family
GKAFKPJL_02304 5.86e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKAFKPJL_02305 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
GKAFKPJL_02306 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
GKAFKPJL_02307 9.34e-176 azlC - - E - - - AzlC protein
GKAFKPJL_02308 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
GKAFKPJL_02309 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
GKAFKPJL_02310 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
GKAFKPJL_02311 6.6e-201 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GKAFKPJL_02312 1.44e-86 yodA - - S - - - tautomerase
GKAFKPJL_02314 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
GKAFKPJL_02315 6.01e-99 xkdM - - S - - - Phage tail tube protein
GKAFKPJL_02316 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
GKAFKPJL_02317 2.87e-101 xkdJ - - - - - - -
GKAFKPJL_02318 8.3e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
GKAFKPJL_02319 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
GKAFKPJL_02320 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
GKAFKPJL_02321 3.91e-217 xkdG - - S - - - Phage capsid family
GKAFKPJL_02322 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
GKAFKPJL_02323 0.0 yqbA - - S - - - portal protein
GKAFKPJL_02324 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
GKAFKPJL_02325 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
GKAFKPJL_02326 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GKAFKPJL_02330 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
GKAFKPJL_02331 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
GKAFKPJL_02333 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
GKAFKPJL_02334 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
GKAFKPJL_02335 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
GKAFKPJL_02336 3.73e-137 yjqB - - S - - - Pfam:DUF867
GKAFKPJL_02337 1.35e-80 yjqA - - S - - - Bacterial PH domain
GKAFKPJL_02338 5.12e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
GKAFKPJL_02339 1.79e-55 - - - S - - - YCII-related domain
GKAFKPJL_02341 3.5e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKAFKPJL_02342 1.67e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
GKAFKPJL_02343 2.71e-103 yjoA - - S - - - DinB family
GKAFKPJL_02344 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
GKAFKPJL_02345 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
GKAFKPJL_02346 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
GKAFKPJL_02347 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
GKAFKPJL_02348 9.24e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
GKAFKPJL_02349 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02350 3.92e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
GKAFKPJL_02351 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
GKAFKPJL_02352 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
GKAFKPJL_02353 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
GKAFKPJL_02354 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
GKAFKPJL_02355 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKAFKPJL_02356 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
GKAFKPJL_02357 1e-117 yjlB - - S - - - Cupin domain
GKAFKPJL_02358 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
GKAFKPJL_02359 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
GKAFKPJL_02360 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
GKAFKPJL_02361 4.82e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
GKAFKPJL_02362 1.11e-41 - - - - - - - -
GKAFKPJL_02363 4.84e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GKAFKPJL_02364 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKAFKPJL_02366 3.7e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
GKAFKPJL_02368 2.27e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
GKAFKPJL_02369 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
GKAFKPJL_02370 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
GKAFKPJL_02371 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
GKAFKPJL_02372 1.42e-213 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
GKAFKPJL_02373 1.95e-30 yjfB - - S - - - Putative motility protein
GKAFKPJL_02374 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
GKAFKPJL_02375 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
GKAFKPJL_02377 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GKAFKPJL_02378 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
GKAFKPJL_02379 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
GKAFKPJL_02380 1.12e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKAFKPJL_02382 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKAFKPJL_02383 5.1e-73 yjdF3 - - S - - - Protein of unknown function (DUF2992)
GKAFKPJL_02384 5.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKAFKPJL_02385 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_02386 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
GKAFKPJL_02387 0.000388 - - - - - - - -
GKAFKPJL_02388 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_02389 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
GKAFKPJL_02390 2.49e-07 - - - - - - - -
GKAFKPJL_02391 3.94e-26 - - - - - - - -
GKAFKPJL_02392 1.92e-47 - - - - - - - -
GKAFKPJL_02393 1.42e-09 - - - S - - - YolD-like protein
GKAFKPJL_02396 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
GKAFKPJL_02398 1.33e-50 - - - - - - - -
GKAFKPJL_02401 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
GKAFKPJL_02402 1.42e-102 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
GKAFKPJL_02403 1.07e-269 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
GKAFKPJL_02404 9.72e-96 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GKAFKPJL_02405 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
GKAFKPJL_02406 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
GKAFKPJL_02407 1.83e-96 yvyF - - S - - - flagellar protein
GKAFKPJL_02408 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
GKAFKPJL_02409 7.06e-102 yvyG - - NOU - - - FlgN protein
GKAFKPJL_02410 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
GKAFKPJL_02411 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
GKAFKPJL_02412 6.92e-92 yviE - - - - - - -
GKAFKPJL_02413 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GKAFKPJL_02414 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GKAFKPJL_02415 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKAFKPJL_02416 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
GKAFKPJL_02417 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GKAFKPJL_02418 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
GKAFKPJL_02419 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
GKAFKPJL_02420 9.14e-88 - - - - - - - -
GKAFKPJL_02421 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKAFKPJL_02422 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKAFKPJL_02423 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKAFKPJL_02424 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
GKAFKPJL_02425 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
GKAFKPJL_02426 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
GKAFKPJL_02427 3.02e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GKAFKPJL_02428 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
GKAFKPJL_02429 1.38e-73 swrA - - S - - - Swarming motility protein
GKAFKPJL_02430 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKAFKPJL_02431 5.24e-296 yvkA - - P - - - -transporter
GKAFKPJL_02432 2.36e-130 yvkB - - K - - - Transcriptional regulator
GKAFKPJL_02433 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
GKAFKPJL_02434 2.54e-42 csbA - - S - - - protein conserved in bacteria
GKAFKPJL_02435 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKAFKPJL_02436 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GKAFKPJL_02437 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GKAFKPJL_02438 2.25e-45 yvkN - - - - - - -
GKAFKPJL_02439 3.3e-64 yvlA - - - - - - -
GKAFKPJL_02440 1.12e-218 yvlB - - S - - - Putative adhesin
GKAFKPJL_02441 2.49e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
GKAFKPJL_02442 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
GKAFKPJL_02443 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
GKAFKPJL_02444 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_02445 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
GKAFKPJL_02446 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
GKAFKPJL_02447 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_02448 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
GKAFKPJL_02449 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
GKAFKPJL_02450 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKAFKPJL_02451 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKAFKPJL_02452 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKAFKPJL_02453 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKAFKPJL_02454 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
GKAFKPJL_02455 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GKAFKPJL_02456 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GKAFKPJL_02457 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
GKAFKPJL_02458 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
GKAFKPJL_02459 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GKAFKPJL_02460 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GKAFKPJL_02461 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GKAFKPJL_02462 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
GKAFKPJL_02463 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GKAFKPJL_02464 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GKAFKPJL_02465 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GKAFKPJL_02466 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
GKAFKPJL_02467 6.36e-172 - - - - - - - -
GKAFKPJL_02468 0.0 - - - - - - - -
GKAFKPJL_02470 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
GKAFKPJL_02471 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
GKAFKPJL_02472 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
GKAFKPJL_02473 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKAFKPJL_02474 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GKAFKPJL_02475 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
GKAFKPJL_02476 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
GKAFKPJL_02477 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
GKAFKPJL_02478 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
GKAFKPJL_02479 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
GKAFKPJL_02480 1.37e-45 - - - - - - - -
GKAFKPJL_02481 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_02482 1.32e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
GKAFKPJL_02483 9e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_02484 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
GKAFKPJL_02485 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKAFKPJL_02486 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
GKAFKPJL_02487 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
GKAFKPJL_02488 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
GKAFKPJL_02489 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
GKAFKPJL_02490 1.54e-221 yvdE - - K - - - Transcriptional regulator
GKAFKPJL_02491 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
GKAFKPJL_02492 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GKAFKPJL_02493 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GKAFKPJL_02494 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GKAFKPJL_02495 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
GKAFKPJL_02496 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
GKAFKPJL_02497 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKAFKPJL_02498 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
GKAFKPJL_02499 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKAFKPJL_02501 9.45e-234 - - - S - - - Patatin-like phospholipase
GKAFKPJL_02502 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
GKAFKPJL_02503 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
GKAFKPJL_02504 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
GKAFKPJL_02505 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
GKAFKPJL_02506 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
GKAFKPJL_02507 0.0 ybeC - - E - - - amino acid
GKAFKPJL_02508 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
GKAFKPJL_02509 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
GKAFKPJL_02510 0.0 pbpE - - V - - - Beta-lactamase
GKAFKPJL_02511 1.76e-162 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
GKAFKPJL_02512 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
GKAFKPJL_02513 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
GKAFKPJL_02515 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
GKAFKPJL_02516 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
GKAFKPJL_02517 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
GKAFKPJL_02518 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GKAFKPJL_02519 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
GKAFKPJL_02520 4.5e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
GKAFKPJL_02521 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_02522 3.68e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
GKAFKPJL_02523 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
GKAFKPJL_02524 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GKAFKPJL_02525 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
GKAFKPJL_02526 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_02527 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_02528 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GKAFKPJL_02529 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
GKAFKPJL_02530 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
GKAFKPJL_02531 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
GKAFKPJL_02532 5.69e-44 yvfG - - S - - - YvfG protein
GKAFKPJL_02533 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GKAFKPJL_02534 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
GKAFKPJL_02535 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
GKAFKPJL_02536 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_02537 1.68e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
GKAFKPJL_02538 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
GKAFKPJL_02539 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
GKAFKPJL_02540 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
GKAFKPJL_02541 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
GKAFKPJL_02542 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
GKAFKPJL_02543 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
GKAFKPJL_02544 1.7e-208 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
GKAFKPJL_02545 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
GKAFKPJL_02546 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02547 2.07e-134 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_02548 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GKAFKPJL_02549 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GKAFKPJL_02550 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GKAFKPJL_02551 1.22e-248 - - - S - - - Glycosyl hydrolase
GKAFKPJL_02552 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_02553 3.93e-198 yvbV - - EG - - - EamA-like transporter family
GKAFKPJL_02554 5.49e-205 yvbU - - K - - - Transcriptional regulator
GKAFKPJL_02556 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_02557 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
GKAFKPJL_02558 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKAFKPJL_02559 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GKAFKPJL_02560 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GKAFKPJL_02561 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
GKAFKPJL_02562 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKAFKPJL_02563 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
GKAFKPJL_02564 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKAFKPJL_02565 6.87e-106 yvbK - - K - - - acetyltransferase
GKAFKPJL_02566 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
GKAFKPJL_02567 1.61e-156 yvbI - - M - - - Membrane
GKAFKPJL_02568 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
GKAFKPJL_02569 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
GKAFKPJL_02570 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GKAFKPJL_02571 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GKAFKPJL_02572 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKAFKPJL_02573 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GKAFKPJL_02574 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKAFKPJL_02575 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
GKAFKPJL_02576 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GKAFKPJL_02577 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKAFKPJL_02578 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GKAFKPJL_02579 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
GKAFKPJL_02580 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02581 3.85e-72 yvaP - - K - - - transcriptional
GKAFKPJL_02582 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GKAFKPJL_02583 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
GKAFKPJL_02584 3.44e-48 yvzC - - K - - - transcriptional
GKAFKPJL_02585 5.5e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
GKAFKPJL_02586 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
GKAFKPJL_02587 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
GKAFKPJL_02588 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKAFKPJL_02589 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GKAFKPJL_02591 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02592 1.17e-126 - - - K - - - Bacterial regulatory proteins, tetR family
GKAFKPJL_02593 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
GKAFKPJL_02594 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
GKAFKPJL_02595 0.0 - - - S - - - Fusaric acid resistance protein-like
GKAFKPJL_02596 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GKAFKPJL_02597 1.71e-248 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKAFKPJL_02598 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
GKAFKPJL_02599 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
GKAFKPJL_02600 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
GKAFKPJL_02601 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GKAFKPJL_02602 3.45e-137 bdbD - - O - - - Thioredoxin
GKAFKPJL_02603 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
GKAFKPJL_02604 2.34e-139 yvgT - - S - - - membrane
GKAFKPJL_02606 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
GKAFKPJL_02607 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GKAFKPJL_02608 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GKAFKPJL_02609 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
GKAFKPJL_02610 7.97e-113 yvgO - - - - - - -
GKAFKPJL_02611 6.19e-201 yvgN - - S - - - reductase
GKAFKPJL_02612 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
GKAFKPJL_02613 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
GKAFKPJL_02614 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
GKAFKPJL_02615 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
GKAFKPJL_02616 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
GKAFKPJL_02617 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
GKAFKPJL_02618 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
GKAFKPJL_02620 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_02621 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_02622 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_02623 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKAFKPJL_02624 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
GKAFKPJL_02625 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_02626 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKAFKPJL_02627 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
GKAFKPJL_02628 4.39e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GKAFKPJL_02629 3.46e-26 - - - S - - - YvrJ protein family
GKAFKPJL_02630 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
GKAFKPJL_02631 5.07e-32 - - - - - - - -
GKAFKPJL_02632 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_02633 0.0 yvrG - - T - - - Histidine kinase
GKAFKPJL_02634 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
GKAFKPJL_02635 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02636 3.48e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GKAFKPJL_02637 6.35e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKAFKPJL_02638 3.76e-316 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GKAFKPJL_02639 2.96e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
GKAFKPJL_02640 6.23e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_02641 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
GKAFKPJL_02642 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GKAFKPJL_02643 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
GKAFKPJL_02644 1.27e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
GKAFKPJL_02645 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02646 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_02647 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
GKAFKPJL_02648 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GKAFKPJL_02649 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKAFKPJL_02650 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
GKAFKPJL_02651 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GKAFKPJL_02652 3.06e-204 yuxN - - K - - - Transcriptional regulator
GKAFKPJL_02653 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02654 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_02655 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKAFKPJL_02656 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
GKAFKPJL_02657 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02658 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
GKAFKPJL_02659 3.48e-88 - - - S - - - YusW-like protein
GKAFKPJL_02660 3.56e-195 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
GKAFKPJL_02661 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
GKAFKPJL_02662 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
GKAFKPJL_02663 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02664 2.93e-85 yusQ - - S - - - Tautomerase enzyme
GKAFKPJL_02665 0.0 yusP - - P - - - Major facilitator superfamily
GKAFKPJL_02666 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
GKAFKPJL_02667 8.66e-70 yusN - - M - - - Coat F domain
GKAFKPJL_02668 2.23e-54 - - - - - - - -
GKAFKPJL_02669 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
GKAFKPJL_02670 1.11e-13 - - - S - - - YuzL-like protein
GKAFKPJL_02671 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
GKAFKPJL_02672 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
GKAFKPJL_02673 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GKAFKPJL_02674 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
GKAFKPJL_02675 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GKAFKPJL_02676 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
GKAFKPJL_02677 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
GKAFKPJL_02678 2e-73 yusE - - CO - - - Thioredoxin
GKAFKPJL_02679 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
GKAFKPJL_02680 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKAFKPJL_02681 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
GKAFKPJL_02682 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
GKAFKPJL_02683 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GKAFKPJL_02684 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GKAFKPJL_02685 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
GKAFKPJL_02686 1.14e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKAFKPJL_02687 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
GKAFKPJL_02688 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
GKAFKPJL_02689 3.35e-56 - - - - - - - -
GKAFKPJL_02691 1.3e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
GKAFKPJL_02692 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
GKAFKPJL_02693 1.29e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GKAFKPJL_02694 6.75e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
GKAFKPJL_02695 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
GKAFKPJL_02696 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
GKAFKPJL_02697 5.1e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
GKAFKPJL_02698 5.04e-174 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
GKAFKPJL_02699 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_02700 1.8e-215 bsn - - L - - - Ribonuclease
GKAFKPJL_02701 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GKAFKPJL_02702 5.74e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GKAFKPJL_02703 1.35e-238 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GKAFKPJL_02704 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
GKAFKPJL_02705 8.04e-193 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GKAFKPJL_02706 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GKAFKPJL_02707 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GKAFKPJL_02708 2.01e-70 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
GKAFKPJL_02709 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
GKAFKPJL_02710 1.84e-282 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
GKAFKPJL_02711 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
GKAFKPJL_02712 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
GKAFKPJL_02713 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GKAFKPJL_02714 1.07e-79 yunG - - - - - - -
GKAFKPJL_02715 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
GKAFKPJL_02716 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
GKAFKPJL_02717 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
GKAFKPJL_02718 3.28e-63 yunC - - S - - - Domain of unknown function (DUF1805)
GKAFKPJL_02719 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
GKAFKPJL_02720 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
GKAFKPJL_02721 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GKAFKPJL_02722 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GKAFKPJL_02723 3.2e-63 yutD - - S - - - protein conserved in bacteria
GKAFKPJL_02724 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
GKAFKPJL_02725 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKAFKPJL_02726 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
GKAFKPJL_02727 1.55e-253 yutH - - S - - - Spore coat protein
GKAFKPJL_02728 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
GKAFKPJL_02729 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GKAFKPJL_02730 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKAFKPJL_02731 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
GKAFKPJL_02732 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
GKAFKPJL_02733 5.44e-74 yuzD - - S - - - protein conserved in bacteria
GKAFKPJL_02734 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKAFKPJL_02735 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
GKAFKPJL_02736 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKAFKPJL_02737 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKAFKPJL_02738 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
GKAFKPJL_02739 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_02740 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
GKAFKPJL_02741 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GKAFKPJL_02743 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
GKAFKPJL_02744 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
GKAFKPJL_02745 1.14e-45 yuiB - - S - - - Putative membrane protein
GKAFKPJL_02746 1.62e-149 yuiC - - S - - - protein conserved in bacteria
GKAFKPJL_02747 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
GKAFKPJL_02748 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GKAFKPJL_02749 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
GKAFKPJL_02750 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
GKAFKPJL_02751 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
GKAFKPJL_02752 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
GKAFKPJL_02753 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_02754 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
GKAFKPJL_02755 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
GKAFKPJL_02756 4.47e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
GKAFKPJL_02757 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_02758 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
GKAFKPJL_02759 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
GKAFKPJL_02760 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
GKAFKPJL_02761 8.49e-292 yukF - - QT - - - Transcriptional regulator
GKAFKPJL_02762 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
GKAFKPJL_02763 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
GKAFKPJL_02764 3.93e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
GKAFKPJL_02765 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GKAFKPJL_02766 0.0 yueB - - S - - - type VII secretion protein EsaA
GKAFKPJL_02767 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
GKAFKPJL_02768 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_02769 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
GKAFKPJL_02770 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
GKAFKPJL_02771 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
GKAFKPJL_02772 5.5e-244 yueF - - S - - - transporter activity
GKAFKPJL_02773 2.05e-42 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
GKAFKPJL_02774 1.63e-52 yueH - - S - - - YueH-like protein
GKAFKPJL_02775 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
GKAFKPJL_02776 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
GKAFKPJL_02777 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKAFKPJL_02778 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
GKAFKPJL_02779 8.73e-09 yuzC - - - - - - -
GKAFKPJL_02780 6.29e-10 - - - S - - - DegQ (SacQ) family
GKAFKPJL_02781 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
GKAFKPJL_02783 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02784 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_02785 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
GKAFKPJL_02786 9.92e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
GKAFKPJL_02787 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKAFKPJL_02788 6.08e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKAFKPJL_02789 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKAFKPJL_02790 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKAFKPJL_02791 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GKAFKPJL_02792 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GKAFKPJL_02793 1.73e-22 - - - - - - - -
GKAFKPJL_02794 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
GKAFKPJL_02795 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKAFKPJL_02796 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKAFKPJL_02797 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_02798 1.28e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
GKAFKPJL_02799 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
GKAFKPJL_02800 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
GKAFKPJL_02801 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
GKAFKPJL_02802 3.31e-98 yuxK - - S - - - protein conserved in bacteria
GKAFKPJL_02803 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
GKAFKPJL_02804 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
GKAFKPJL_02806 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
GKAFKPJL_02807 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
GKAFKPJL_02808 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_02809 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GKAFKPJL_02810 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
GKAFKPJL_02811 9.89e-201 yugF - - I - - - Hydrolase
GKAFKPJL_02812 6.74e-112 alaR - - K - - - Transcriptional regulator
GKAFKPJL_02813 3.14e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
GKAFKPJL_02814 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GKAFKPJL_02815 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
GKAFKPJL_02816 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
GKAFKPJL_02817 5.34e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
GKAFKPJL_02818 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
GKAFKPJL_02820 9.97e-94 yugN - - S - - - YugN-like family
GKAFKPJL_02821 1.45e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
GKAFKPJL_02822 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
GKAFKPJL_02823 1.58e-50 - - - - - - - -
GKAFKPJL_02824 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
GKAFKPJL_02825 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKAFKPJL_02826 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
GKAFKPJL_02827 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
GKAFKPJL_02828 1.44e-47 - - - - - - - -
GKAFKPJL_02829 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
GKAFKPJL_02830 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02831 1.31e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02832 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02833 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_02834 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
GKAFKPJL_02835 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKAFKPJL_02836 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GKAFKPJL_02837 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
GKAFKPJL_02838 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
GKAFKPJL_02839 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
GKAFKPJL_02840 7.34e-254 yubA - - S - - - transporter activity
GKAFKPJL_02841 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GKAFKPJL_02843 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
GKAFKPJL_02844 0.0 yubD - - P - - - Major Facilitator Superfamily
GKAFKPJL_02845 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKAFKPJL_02846 3.31e-52 yubF - - S - - - yiaA/B two helix domain
GKAFKPJL_02847 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
GKAFKPJL_02848 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
GKAFKPJL_02849 5.83e-118 yuaB - - - - - - -
GKAFKPJL_02850 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
GKAFKPJL_02851 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKAFKPJL_02852 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
GKAFKPJL_02853 8.58e-139 yuaD - - - - - - -
GKAFKPJL_02854 1.95e-109 yuaE - - S - - - DinB superfamily
GKAFKPJL_02855 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
GKAFKPJL_02856 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
GKAFKPJL_02857 1.2e-122 - - - M - - - FR47-like protein
GKAFKPJL_02858 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
GKAFKPJL_02859 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKAFKPJL_02860 1.76e-94 ywhA - - K - - - Transcriptional regulator
GKAFKPJL_02861 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
GKAFKPJL_02862 3.29e-154 ywhC - - S - - - Peptidase family M50
GKAFKPJL_02863 7.83e-123 ywhD - - S - - - YwhD family
GKAFKPJL_02864 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
GKAFKPJL_02865 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GKAFKPJL_02866 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GKAFKPJL_02868 2.32e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKAFKPJL_02869 4.56e-289 ywhK - - CO - - - amine dehydrogenase activity
GKAFKPJL_02870 0.0 ywhL - - CO - - - amine dehydrogenase activity
GKAFKPJL_02872 3.9e-316 - - - L - - - Peptidase, M16
GKAFKPJL_02873 3.29e-274 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
GKAFKPJL_02874 1.98e-296 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
GKAFKPJL_02875 4.3e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
GKAFKPJL_02877 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
GKAFKPJL_02878 3.71e-12 - - - S - - - Bacteriocin subtilosin A
GKAFKPJL_02879 4.64e-96 ywiB - - S - - - protein conserved in bacteria
GKAFKPJL_02880 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
GKAFKPJL_02881 4.81e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
GKAFKPJL_02882 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
GKAFKPJL_02883 1.84e-179 ywiC - - S - - - YwiC-like protein
GKAFKPJL_02884 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
GKAFKPJL_02885 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKAFKPJL_02886 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
GKAFKPJL_02887 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
GKAFKPJL_02888 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
GKAFKPJL_02889 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKAFKPJL_02890 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
GKAFKPJL_02891 7.5e-122 ywjB - - H - - - RibD C-terminal domain
GKAFKPJL_02892 1.32e-57 ywjC - - - - - - -
GKAFKPJL_02893 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GKAFKPJL_02894 9.57e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GKAFKPJL_02895 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
GKAFKPJL_02896 1.65e-266 acdA - - I - - - acyl-CoA dehydrogenase
GKAFKPJL_02897 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKAFKPJL_02898 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKAFKPJL_02899 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
GKAFKPJL_02900 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
GKAFKPJL_02901 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
GKAFKPJL_02902 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GKAFKPJL_02903 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKAFKPJL_02904 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
GKAFKPJL_02905 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GKAFKPJL_02906 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
GKAFKPJL_02907 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
GKAFKPJL_02908 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
GKAFKPJL_02909 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
GKAFKPJL_02910 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GKAFKPJL_02911 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_02912 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKAFKPJL_02913 2.23e-200 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKAFKPJL_02915 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
GKAFKPJL_02916 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
GKAFKPJL_02917 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
GKAFKPJL_02918 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKAFKPJL_02919 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
GKAFKPJL_02920 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKAFKPJL_02921 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
GKAFKPJL_02922 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
GKAFKPJL_02923 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKAFKPJL_02924 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKAFKPJL_02925 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
GKAFKPJL_02926 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
GKAFKPJL_02927 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKAFKPJL_02928 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKAFKPJL_02929 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKAFKPJL_02930 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKAFKPJL_02931 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKAFKPJL_02932 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKAFKPJL_02933 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
GKAFKPJL_02934 2.8e-111 ywmA - - - - - - -
GKAFKPJL_02935 4.54e-45 ywzB - - S - - - membrane
GKAFKPJL_02936 2.68e-171 ywmB - - S - - - TATA-box binding
GKAFKPJL_02937 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKAFKPJL_02938 3.41e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
GKAFKPJL_02939 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKAFKPJL_02940 1.44e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKAFKPJL_02942 3.69e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GKAFKPJL_02943 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GKAFKPJL_02944 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
GKAFKPJL_02945 1.12e-109 ywmF - - S - - - Peptidase M50
GKAFKPJL_02946 1.84e-20 csbD - - K - - - CsbD-like
GKAFKPJL_02948 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
GKAFKPJL_02949 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
GKAFKPJL_02950 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GKAFKPJL_02951 2.65e-84 ywnA - - K - - - Transcriptional regulator
GKAFKPJL_02952 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
GKAFKPJL_02953 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
GKAFKPJL_02954 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
GKAFKPJL_02955 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKAFKPJL_02956 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
GKAFKPJL_02957 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
GKAFKPJL_02958 7.38e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
GKAFKPJL_02959 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
GKAFKPJL_02960 7.75e-94 ywnJ - - S - - - VanZ like family
GKAFKPJL_02961 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
GKAFKPJL_02962 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
GKAFKPJL_02963 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
GKAFKPJL_02964 5.04e-101 - - - - - - - -
GKAFKPJL_02965 1.04e-133 yjgF - - Q - - - Isochorismatase family
GKAFKPJL_02966 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
GKAFKPJL_02967 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
GKAFKPJL_02968 2.4e-311 ywoF - - P - - - Right handed beta helix region
GKAFKPJL_02969 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_02970 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
GKAFKPJL_02971 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
GKAFKPJL_02972 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
GKAFKPJL_02973 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GKAFKPJL_02974 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
GKAFKPJL_02975 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
GKAFKPJL_02976 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKAFKPJL_02977 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKAFKPJL_02978 1.28e-66 ywpD - - T - - - Histidine kinase
GKAFKPJL_02979 2.51e-18 - - - M - - - cell wall anchor domain
GKAFKPJL_02980 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
GKAFKPJL_02981 3.59e-88 ywpF - - S - - - YwpF-like protein
GKAFKPJL_02982 3.56e-86 ywpG - - - - - - -
GKAFKPJL_02983 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
GKAFKPJL_02984 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKAFKPJL_02985 5.91e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKAFKPJL_02986 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
GKAFKPJL_02987 0.0 ywqB - - S - - - SWIM zinc finger
GKAFKPJL_02988 3.6e-25 - - - - - - - -
GKAFKPJL_02989 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
GKAFKPJL_02990 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
GKAFKPJL_02991 6.38e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
GKAFKPJL_02992 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKAFKPJL_02993 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
GKAFKPJL_02995 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
GKAFKPJL_02996 1.95e-297 ywqJ - - S - - - Pre-toxin TG
GKAFKPJL_02997 1.29e-97 - - - - - - - -
GKAFKPJL_02998 2.2e-66 - - - - - - - -
GKAFKPJL_03000 1.13e-126 - - - - - - - -
GKAFKPJL_03001 4.92e-154 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GKAFKPJL_03002 3.89e-208 - - - K - - - Transcriptional regulator
GKAFKPJL_03003 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
GKAFKPJL_03005 4.27e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
GKAFKPJL_03006 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
GKAFKPJL_03007 1.81e-35 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
GKAFKPJL_03008 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
GKAFKPJL_03009 1.22e-09 - - - S - - - Domain of unknown function (DUF4181)
GKAFKPJL_03010 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKAFKPJL_03011 2.17e-16 - - - - - - - -
GKAFKPJL_03012 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
GKAFKPJL_03013 1.37e-194 cotB - - - ko:K06325 - ko00000 -
GKAFKPJL_03014 2.5e-161 ywrJ - - - - - - -
GKAFKPJL_03015 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GKAFKPJL_03016 3.36e-218 alsR - - K - - - LysR substrate binding domain
GKAFKPJL_03017 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
GKAFKPJL_03018 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
GKAFKPJL_03019 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
GKAFKPJL_03020 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
GKAFKPJL_03021 1.62e-118 batE - - T - - - Sh3 type 3 domain protein
GKAFKPJL_03022 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
GKAFKPJL_03023 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
GKAFKPJL_03024 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GKAFKPJL_03025 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GKAFKPJL_03026 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKAFKPJL_03027 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
GKAFKPJL_03028 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
GKAFKPJL_03029 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
GKAFKPJL_03030 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GKAFKPJL_03031 2.29e-29 ywtC - - - - - - -
GKAFKPJL_03032 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GKAFKPJL_03033 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
GKAFKPJL_03034 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
GKAFKPJL_03035 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKAFKPJL_03036 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
GKAFKPJL_03037 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
GKAFKPJL_03038 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKAFKPJL_03039 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
GKAFKPJL_03040 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GKAFKPJL_03041 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKAFKPJL_03042 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKAFKPJL_03043 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
GKAFKPJL_03044 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
GKAFKPJL_03045 1.01e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKAFKPJL_03046 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GKAFKPJL_03047 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
GKAFKPJL_03048 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKAFKPJL_03049 4.14e-106 - - - M - - - Glycosyltransferase like family 2
GKAFKPJL_03050 7.58e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GKAFKPJL_03051 5.37e-68 - - - - - - - -
GKAFKPJL_03052 7.8e-102 - - - - - - - -
GKAFKPJL_03053 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
GKAFKPJL_03054 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GKAFKPJL_03055 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKAFKPJL_03057 3.05e-119 - - - M - - - Glycosyl transferases group 1
GKAFKPJL_03058 2.94e-103 - - - M - - - Glycosyltransferase like family 2
GKAFKPJL_03059 7.71e-277 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GKAFKPJL_03060 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GKAFKPJL_03061 9.07e-16 - - - - - - - -
GKAFKPJL_03062 0.0 lytB - - D - - - Stage II sporulation protein
GKAFKPJL_03063 2.25e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKAFKPJL_03064 7e-108 - - - M - - - Glycosyltransferase like family 2
GKAFKPJL_03065 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GKAFKPJL_03066 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_03067 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
GKAFKPJL_03068 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GKAFKPJL_03069 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
GKAFKPJL_03070 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
GKAFKPJL_03071 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
GKAFKPJL_03072 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
GKAFKPJL_03073 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GKAFKPJL_03074 3.81e-223 yvhJ - - K - - - Transcriptional regulator
GKAFKPJL_03075 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
GKAFKPJL_03076 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GKAFKPJL_03077 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKAFKPJL_03078 1.77e-198 degV - - S - - - protein conserved in bacteria
GKAFKPJL_03079 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_03080 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GKAFKPJL_03081 1.71e-143 ykoX - - S - - - membrane-associated protein
GKAFKPJL_03082 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
GKAFKPJL_03083 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GKAFKPJL_03084 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
GKAFKPJL_03085 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_03086 0.0 ykoS - - - - - - -
GKAFKPJL_03087 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
GKAFKPJL_03088 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
GKAFKPJL_03089 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
GKAFKPJL_03090 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
GKAFKPJL_03091 3.04e-36 ykoL - - - - - - -
GKAFKPJL_03092 1.63e-25 - - - - - - - -
GKAFKPJL_03093 1.49e-70 tnrA - - K - - - transcriptional
GKAFKPJL_03094 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
GKAFKPJL_03096 1.45e-08 - - - - - - - -
GKAFKPJL_03097 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
GKAFKPJL_03098 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
GKAFKPJL_03099 3.13e-309 ykoH - - T - - - Histidine kinase
GKAFKPJL_03100 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_03101 1.36e-139 ykoF - - S - - - YKOF-related Family
GKAFKPJL_03102 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
GKAFKPJL_03103 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_03104 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
GKAFKPJL_03105 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GKAFKPJL_03106 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_03107 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GKAFKPJL_03108 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
GKAFKPJL_03109 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
GKAFKPJL_03110 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
GKAFKPJL_03111 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
GKAFKPJL_03113 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKAFKPJL_03114 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKAFKPJL_03115 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GKAFKPJL_03116 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
GKAFKPJL_03117 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
GKAFKPJL_03118 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKAFKPJL_03119 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
GKAFKPJL_03120 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
GKAFKPJL_03121 5.85e-13 - - - - - - - -
GKAFKPJL_03122 2.73e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GKAFKPJL_03123 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
GKAFKPJL_03124 1.78e-205 ykgA - - E - - - Amidinotransferase
GKAFKPJL_03125 3.29e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
GKAFKPJL_03126 3.58e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_03127 2.17e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GKAFKPJL_03128 1.62e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
GKAFKPJL_03129 6.49e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
GKAFKPJL_03131 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
GKAFKPJL_03132 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_03133 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_03134 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GKAFKPJL_03135 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
GKAFKPJL_03136 2.25e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
GKAFKPJL_03137 2.4e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKAFKPJL_03139 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_03140 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKAFKPJL_03141 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
GKAFKPJL_03142 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
GKAFKPJL_03143 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
GKAFKPJL_03144 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
GKAFKPJL_03145 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
GKAFKPJL_03146 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
GKAFKPJL_03148 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
GKAFKPJL_03149 1.15e-52 xhlB - - S - - - SPP1 phage holin
GKAFKPJL_03150 2.21e-51 xhlA - - S - - - Haemolysin XhlA
GKAFKPJL_03151 2.21e-193 xepA - - - - - - -
GKAFKPJL_03152 6.35e-31 xkdX - - - - - - -
GKAFKPJL_03153 1.28e-59 xkdW - - S - - - XkdW protein
GKAFKPJL_03154 7.11e-148 - - - - - - - -
GKAFKPJL_03155 2.6e-111 - - - - - - - -
GKAFKPJL_03156 4.43e-56 - - - - - - - -
GKAFKPJL_03157 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
GKAFKPJL_03158 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GKAFKPJL_03159 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
GKAFKPJL_03160 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
GKAFKPJL_03161 1.56e-230 xkdQ - - G - - - NLP P60 protein
GKAFKPJL_03162 4.25e-152 xkdP - - S - - - Lysin motif
GKAFKPJL_03163 0.0 xkdO - - L - - - Transglycosylase SLT domain
GKAFKPJL_03164 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKAFKPJL_03165 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKAFKPJL_03166 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
GKAFKPJL_03167 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKAFKPJL_03168 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
GKAFKPJL_03169 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKAFKPJL_03170 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKAFKPJL_03171 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKAFKPJL_03172 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKAFKPJL_03173 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
GKAFKPJL_03174 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKAFKPJL_03175 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKAFKPJL_03176 5.86e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GKAFKPJL_03177 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GKAFKPJL_03178 9.26e-98 - - - S - - - Bacterial PH domain
GKAFKPJL_03179 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
GKAFKPJL_03180 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
GKAFKPJL_03181 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
GKAFKPJL_03182 5.34e-227 yyaD - - S - - - Membrane
GKAFKPJL_03183 7.41e-45 yyzM - - S - - - protein conserved in bacteria
GKAFKPJL_03184 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKAFKPJL_03185 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKAFKPJL_03186 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
GKAFKPJL_03187 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKAFKPJL_03188 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKAFKPJL_03189 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
GKAFKPJL_03190 1.29e-198 ccpB - - K - - - Transcriptional regulator
GKAFKPJL_03191 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_03192 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
GKAFKPJL_03193 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
GKAFKPJL_03194 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
GKAFKPJL_03195 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
GKAFKPJL_03196 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_03197 8.62e-137 yyaP - - H - - - RibD C-terminal domain
GKAFKPJL_03198 1.5e-85 - - - S - - - YjbR
GKAFKPJL_03199 2.72e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
GKAFKPJL_03200 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
GKAFKPJL_03201 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKAFKPJL_03202 4.54e-100 yybA - - K - - - transcriptional
GKAFKPJL_03203 1.03e-162 - - - S - - - Metallo-beta-lactamase superfamily
GKAFKPJL_03204 1.66e-95 yybC - - - - - - -
GKAFKPJL_03205 2.18e-101 yjcF - - S - - - Acetyltransferase (GNAT) domain
GKAFKPJL_03206 7.57e-210 yybE - - K - - - Transcriptional regulator
GKAFKPJL_03207 2.04e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_03208 5.67e-162 yybG - - S - - - Pentapeptide repeat-containing protein
GKAFKPJL_03209 2.49e-87 - - - S - - - SnoaL-like domain
GKAFKPJL_03210 2.05e-183 - - - - - - - -
GKAFKPJL_03211 1.46e-140 - - - K - - - TipAS antibiotic-recognition domain
GKAFKPJL_03212 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_03214 3.19e-90 - - - - - - - -
GKAFKPJL_03215 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
GKAFKPJL_03216 1.35e-89 yybR - - K - - - Transcriptional regulator
GKAFKPJL_03217 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
GKAFKPJL_03219 8.66e-204 yybS - - S - - - membrane
GKAFKPJL_03220 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
GKAFKPJL_03221 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GKAFKPJL_03222 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKAFKPJL_03223 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
GKAFKPJL_03224 1.89e-22 yycC - - K - - - YycC-like protein
GKAFKPJL_03226 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
GKAFKPJL_03227 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
GKAFKPJL_03228 3.85e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_03229 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKAFKPJL_03234 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_03235 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_03236 0.0 yycH - - S - - - protein conserved in bacteria
GKAFKPJL_03237 1.63e-198 yycI - - S - - - protein conserved in bacteria
GKAFKPJL_03238 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GKAFKPJL_03239 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKAFKPJL_03240 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
GKAFKPJL_03241 3.28e-98 - - - S - - - Peptidase propeptide and YPEB domain
GKAFKPJL_03242 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
GKAFKPJL_03243 3.51e-212 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GKAFKPJL_03244 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GKAFKPJL_03245 9.1e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
GKAFKPJL_03246 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKAFKPJL_03247 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
GKAFKPJL_03249 1.06e-239 - - - S - - - aspartate phosphatase
GKAFKPJL_03250 5.25e-111 yycN - - K - - - Acetyltransferase
GKAFKPJL_03251 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GKAFKPJL_03252 1.17e-270 yycP - - - - - - -
GKAFKPJL_03253 2.24e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
GKAFKPJL_03255 4.27e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GKAFKPJL_03256 2.24e-87 - - - - - - - -
GKAFKPJL_03258 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKAFKPJL_03260 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
GKAFKPJL_03261 1.99e-17 - - - - - - - -
GKAFKPJL_03262 7.8e-237 - - - S - - - Radical SAM superfamily
GKAFKPJL_03263 1e-169 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
GKAFKPJL_03264 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_03265 5.49e-152 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
GKAFKPJL_03266 1.44e-24 - - - - - - - -
GKAFKPJL_03267 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_03268 7.55e-44 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
GKAFKPJL_03269 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKAFKPJL_03270 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
GKAFKPJL_03271 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
GKAFKPJL_03272 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
GKAFKPJL_03273 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKAFKPJL_03274 2.91e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
GKAFKPJL_03275 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
GKAFKPJL_03276 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
GKAFKPJL_03277 3.87e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
GKAFKPJL_03278 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
GKAFKPJL_03279 2.19e-153 yxaC - - M - - - effector of murein hydrolase
GKAFKPJL_03280 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
GKAFKPJL_03281 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
GKAFKPJL_03282 1.5e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_03283 1.59e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
GKAFKPJL_03284 1.22e-249 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
GKAFKPJL_03285 4.89e-282 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GKAFKPJL_03286 4.03e-99 yxaI - - S - - - membrane protein domain
GKAFKPJL_03287 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
GKAFKPJL_03288 1.73e-135 yxaL - - S - - - PQQ-like domain
GKAFKPJL_03289 2.09e-16 yxaI - - S - - - membrane protein domain
GKAFKPJL_03290 9.79e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKAFKPJL_03291 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
GKAFKPJL_03292 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_03294 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
GKAFKPJL_03295 6.88e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKAFKPJL_03296 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
GKAFKPJL_03298 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
GKAFKPJL_03299 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
GKAFKPJL_03300 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKAFKPJL_03301 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GKAFKPJL_03302 2.48e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GKAFKPJL_03303 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GKAFKPJL_03304 1.23e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GKAFKPJL_03305 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
GKAFKPJL_03306 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GKAFKPJL_03307 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
GKAFKPJL_03308 1.09e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GKAFKPJL_03309 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GKAFKPJL_03310 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKAFKPJL_03311 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_03312 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_03313 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
GKAFKPJL_03314 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
GKAFKPJL_03315 9.65e-223 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
GKAFKPJL_03316 9.65e-91 - - - - - - - -
GKAFKPJL_03317 7.57e-28 yxeD - - - - - - -
GKAFKPJL_03318 7.32e-42 yxeE - - - - - - -
GKAFKPJL_03321 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
GKAFKPJL_03322 9.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
GKAFKPJL_03323 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_03324 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_03325 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
GKAFKPJL_03326 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
GKAFKPJL_03327 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_03328 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
GKAFKPJL_03329 0.0 yxeQ - - S - - - MmgE/PrpD family
GKAFKPJL_03330 5.43e-256 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
GKAFKPJL_03331 3.05e-196 - - - S - - - Domain of Unknown Function (DUF1206)
GKAFKPJL_03332 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GKAFKPJL_03333 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKAFKPJL_03334 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKAFKPJL_03335 6.66e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
GKAFKPJL_03336 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKAFKPJL_03337 2.8e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GKAFKPJL_03338 9.1e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
GKAFKPJL_03339 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GKAFKPJL_03340 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
GKAFKPJL_03341 1.6e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GKAFKPJL_03342 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
GKAFKPJL_03343 2.18e-36 - - - S - - - Domain of unknown function (DUF5082)
GKAFKPJL_03344 4.47e-51 yxiC - - S - - - Family of unknown function (DUF5344)
GKAFKPJL_03345 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
GKAFKPJL_03347 2.81e-26 - - - S - - - protein conserved in bacteria
GKAFKPJL_03349 1.62e-85 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
GKAFKPJL_03350 2.43e-173 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
GKAFKPJL_03351 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
GKAFKPJL_03352 1.33e-62 - - - - - - - -
GKAFKPJL_03353 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_03354 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
GKAFKPJL_03355 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
GKAFKPJL_03356 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
GKAFKPJL_03357 1.24e-113 - - - - - - - -
GKAFKPJL_03359 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
GKAFKPJL_03360 2.2e-28 - - - - - - - -
GKAFKPJL_03361 8.44e-210 yxxF - - EG - - - EamA-like transporter family
GKAFKPJL_03362 0.0 wapA - - M - - - COG3209 Rhs family protein
GKAFKPJL_03363 2.34e-21 - - - S - - - YxiJ-like protein
GKAFKPJL_03364 2.16e-53 - - - S - - - Protein of unknown function (DUF2812)
GKAFKPJL_03365 1.86e-70 - - - K - - - Transcriptional regulator PadR-like family
GKAFKPJL_03366 2.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
GKAFKPJL_03367 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GKAFKPJL_03368 4.43e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
GKAFKPJL_03369 4.37e-142 - - - - - - - -
GKAFKPJL_03370 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKAFKPJL_03371 1.46e-182 bglS - - M - - - licheninase activity
GKAFKPJL_03372 3.31e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
GKAFKPJL_03373 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKAFKPJL_03374 5.39e-62 yxiS - - - - - - -
GKAFKPJL_03375 2.83e-131 - - - T - - - Domain of unknown function (DUF4163)
GKAFKPJL_03376 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GKAFKPJL_03377 2.34e-284 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_03379 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
GKAFKPJL_03380 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
GKAFKPJL_03381 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GKAFKPJL_03382 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
GKAFKPJL_03383 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKAFKPJL_03384 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GKAFKPJL_03385 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
GKAFKPJL_03386 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GKAFKPJL_03387 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GKAFKPJL_03388 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKAFKPJL_03389 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
GKAFKPJL_03390 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
GKAFKPJL_03391 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKAFKPJL_03392 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKAFKPJL_03393 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
GKAFKPJL_03394 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
GKAFKPJL_03395 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GKAFKPJL_03396 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
GKAFKPJL_03397 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKAFKPJL_03398 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKAFKPJL_03399 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKAFKPJL_03400 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKAFKPJL_03401 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
GKAFKPJL_03402 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKAFKPJL_03403 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKAFKPJL_03404 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
GKAFKPJL_03405 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKAFKPJL_03406 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKAFKPJL_03407 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKAFKPJL_03408 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKAFKPJL_03409 8.68e-229 ybaC - - S - - - Alpha/beta hydrolase family
GKAFKPJL_03410 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
GKAFKPJL_03411 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKAFKPJL_03412 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
GKAFKPJL_03413 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKAFKPJL_03414 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKAFKPJL_03415 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKAFKPJL_03416 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKAFKPJL_03417 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKAFKPJL_03418 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKAFKPJL_03419 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
GKAFKPJL_03420 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKAFKPJL_03421 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKAFKPJL_03422 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKAFKPJL_03423 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKAFKPJL_03424 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKAFKPJL_03425 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKAFKPJL_03426 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKAFKPJL_03427 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKAFKPJL_03428 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKAFKPJL_03429 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
GKAFKPJL_03430 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
GKAFKPJL_03431 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKAFKPJL_03432 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKAFKPJL_03433 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
GKAFKPJL_03434 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKAFKPJL_03435 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
GKAFKPJL_03436 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKAFKPJL_03437 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKAFKPJL_03438 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKAFKPJL_03439 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
GKAFKPJL_03440 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKAFKPJL_03441 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKAFKPJL_03442 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKAFKPJL_03443 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKAFKPJL_03444 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKAFKPJL_03445 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
GKAFKPJL_03446 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
GKAFKPJL_03447 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
GKAFKPJL_03448 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
GKAFKPJL_03449 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GKAFKPJL_03450 1.04e-122 gerD - - - ko:K06294 - ko00000 -
GKAFKPJL_03451 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
GKAFKPJL_03452 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
GKAFKPJL_03453 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
GKAFKPJL_03455 3.86e-183 yoaP - - K - - - YoaP-like
GKAFKPJL_03456 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
GKAFKPJL_03458 1.87e-113 - - - - - - - -
GKAFKPJL_03459 1.04e-217 yoaR - - V - - - vancomycin resistance protein
GKAFKPJL_03460 6.5e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
GKAFKPJL_03461 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_03462 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
GKAFKPJL_03463 1.11e-201 yoaU - - K - - - LysR substrate binding domain
GKAFKPJL_03464 1.51e-200 yoaV - - EG - - - EamA-like transporter family
GKAFKPJL_03465 1.89e-100 yoaW - - - - - - -
GKAFKPJL_03466 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
GKAFKPJL_03467 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
GKAFKPJL_03470 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
GKAFKPJL_03471 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
GKAFKPJL_03472 1e-47 - - - S - - - TM2 domain
GKAFKPJL_03473 7.63e-74 - - - K - - - Helix-turn-helix
GKAFKPJL_03476 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
GKAFKPJL_03481 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
GKAFKPJL_03484 6.81e-66 - - - S - - - Tetratricopeptide repeat
GKAFKPJL_03485 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
GKAFKPJL_03493 4.91e-264 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
GKAFKPJL_03495 4.52e-201 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKAFKPJL_03496 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKAFKPJL_03498 3.72e-58 - - - - - - - -
GKAFKPJL_03500 5.21e-26 - - - - - - - -
GKAFKPJL_03501 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GKAFKPJL_03502 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
GKAFKPJL_03503 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
GKAFKPJL_03504 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GKAFKPJL_03505 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GKAFKPJL_03506 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GKAFKPJL_03507 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GKAFKPJL_03508 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
GKAFKPJL_03509 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
GKAFKPJL_03510 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
GKAFKPJL_03511 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GKAFKPJL_03512 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
GKAFKPJL_03513 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GKAFKPJL_03514 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
GKAFKPJL_03515 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
GKAFKPJL_03516 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
GKAFKPJL_03517 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
GKAFKPJL_03518 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
GKAFKPJL_03519 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
GKAFKPJL_03520 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GKAFKPJL_03521 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GKAFKPJL_03522 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
GKAFKPJL_03523 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
GKAFKPJL_03524 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
GKAFKPJL_03525 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
GKAFKPJL_03526 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
GKAFKPJL_03527 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKAFKPJL_03528 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GKAFKPJL_03529 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
GKAFKPJL_03530 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
GKAFKPJL_03531 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GKAFKPJL_03532 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
GKAFKPJL_03533 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
GKAFKPJL_03534 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GKAFKPJL_03535 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GKAFKPJL_03536 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_03537 6.62e-99 ylxL - - - - - - -
GKAFKPJL_03538 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
GKAFKPJL_03539 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKAFKPJL_03540 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
GKAFKPJL_03541 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKAFKPJL_03542 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKAFKPJL_03543 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
GKAFKPJL_03544 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GKAFKPJL_03545 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
GKAFKPJL_03546 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKAFKPJL_03547 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKAFKPJL_03548 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
GKAFKPJL_03549 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
GKAFKPJL_03550 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
GKAFKPJL_03551 6.16e-63 ylxQ - - J - - - ribosomal protein
GKAFKPJL_03552 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKAFKPJL_03553 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
GKAFKPJL_03554 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKAFKPJL_03555 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKAFKPJL_03556 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
GKAFKPJL_03557 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKAFKPJL_03558 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GKAFKPJL_03559 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
GKAFKPJL_03560 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
GKAFKPJL_03561 1.53e-56 ymxH - - S - - - YlmC YmxH family
GKAFKPJL_03562 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
GKAFKPJL_03563 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GKAFKPJL_03564 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKAFKPJL_03565 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
GKAFKPJL_03566 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKAFKPJL_03567 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKAFKPJL_03568 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
GKAFKPJL_03569 4.94e-44 - - - S - - - YlzJ-like protein
GKAFKPJL_03570 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
GKAFKPJL_03571 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_03572 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_03573 1.35e-298 albE - - S - - - Peptidase M16
GKAFKPJL_03574 6.8e-309 ymfH - - S - - - zinc protease
GKAFKPJL_03575 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GKAFKPJL_03576 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
GKAFKPJL_03577 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
GKAFKPJL_03578 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
GKAFKPJL_03579 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKAFKPJL_03580 4.33e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
GKAFKPJL_03581 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKAFKPJL_03582 2.82e-280 pbpX - - V - - - Beta-lactamase
GKAFKPJL_03583 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
GKAFKPJL_03584 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
GKAFKPJL_03585 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
GKAFKPJL_03586 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GKAFKPJL_03587 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GKAFKPJL_03588 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKAFKPJL_03589 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
GKAFKPJL_03590 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
GKAFKPJL_03591 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKAFKPJL_03593 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_03594 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
GKAFKPJL_03595 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
GKAFKPJL_03596 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
GKAFKPJL_03597 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
GKAFKPJL_03598 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
GKAFKPJL_03599 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GKAFKPJL_03600 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
GKAFKPJL_03601 1.19e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
GKAFKPJL_03602 3.89e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
GKAFKPJL_03603 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
GKAFKPJL_03604 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GKAFKPJL_03605 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
GKAFKPJL_03606 2.01e-134 yngC - - S - - - membrane-associated protein
GKAFKPJL_03607 7.53e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
GKAFKPJL_03608 4.06e-102 yngA - - S - - - membrane
GKAFKPJL_03609 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GKAFKPJL_03610 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
GKAFKPJL_03612 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
GKAFKPJL_03613 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
GKAFKPJL_03614 1.06e-75 ynfC - - - - - - -
GKAFKPJL_03615 1.82e-18 - - - - - - - -
GKAFKPJL_03616 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKAFKPJL_03617 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKAFKPJL_03618 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
GKAFKPJL_03619 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKAFKPJL_03620 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
GKAFKPJL_03621 2.32e-71 yneQ - - - - - - -
GKAFKPJL_03622 1.64e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
GKAFKPJL_03623 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
GKAFKPJL_03625 9.26e-10 - - - S - - - Fur-regulated basic protein B
GKAFKPJL_03626 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKAFKPJL_03627 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GKAFKPJL_03628 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
GKAFKPJL_03629 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
GKAFKPJL_03630 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
GKAFKPJL_03631 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
GKAFKPJL_03632 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
GKAFKPJL_03633 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
GKAFKPJL_03634 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
GKAFKPJL_03635 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
GKAFKPJL_03636 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
GKAFKPJL_03637 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
GKAFKPJL_03638 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKAFKPJL_03639 1.15e-43 ynzC - - S - - - UPF0291 protein
GKAFKPJL_03640 4.63e-144 yneB - - L - - - resolvase
GKAFKPJL_03641 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GKAFKPJL_03642 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GKAFKPJL_03643 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GKAFKPJL_03644 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
GKAFKPJL_03645 3.26e-175 yndL - - S - - - Replication protein
GKAFKPJL_03647 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
GKAFKPJL_03648 7.62e-68 yerC - - S - - - protein conserved in bacteria
GKAFKPJL_03649 9.18e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
GKAFKPJL_03650 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
GKAFKPJL_03651 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
GKAFKPJL_03652 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
GKAFKPJL_03653 1.29e-94 - - - K - - - helix_turn_helix ASNC type
GKAFKPJL_03654 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
GKAFKPJL_03655 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
GKAFKPJL_03656 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKAFKPJL_03657 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
GKAFKPJL_03658 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKAFKPJL_03659 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKAFKPJL_03660 4.69e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKAFKPJL_03661 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKAFKPJL_03662 2.04e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
GKAFKPJL_03663 8.03e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKAFKPJL_03664 6.34e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKAFKPJL_03665 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKAFKPJL_03666 3.13e-38 yebG - - S - - - NETI protein
GKAFKPJL_03667 5.36e-120 yebE - - S - - - UPF0316 protein
GKAFKPJL_03669 1.95e-163 yebC - - M - - - Membrane
GKAFKPJL_03670 3.99e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
GKAFKPJL_03671 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
GKAFKPJL_03672 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
GKAFKPJL_03673 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GKAFKPJL_03674 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
GKAFKPJL_03675 1.44e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKAFKPJL_03676 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
GKAFKPJL_03677 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
GKAFKPJL_03678 1.96e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
GKAFKPJL_03679 1.25e-202 - - - I - - - Alpha/beta hydrolase family
GKAFKPJL_03680 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
GKAFKPJL_03682 4.44e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
GKAFKPJL_03683 1.79e-84 ydjM - - M - - - Lytic transglycolase
GKAFKPJL_03684 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
GKAFKPJL_03685 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKAFKPJL_03686 2.18e-245 - - - S - - - Ion transport 2 domain protein
GKAFKPJL_03687 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
GKAFKPJL_03688 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
GKAFKPJL_03689 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKAFKPJL_03690 1.6e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
GKAFKPJL_03691 7.03e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
GKAFKPJL_03692 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
GKAFKPJL_03693 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
GKAFKPJL_03694 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
GKAFKPJL_03695 8.95e-31 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
GKAFKPJL_03696 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
GKAFKPJL_03711 8.81e-204 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
GKAFKPJL_03712 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
GKAFKPJL_03713 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GKAFKPJL_03714 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GKAFKPJL_03715 6.8e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GKAFKPJL_03716 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GKAFKPJL_03717 7.42e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
GKAFKPJL_03718 1.43e-111 yxjI - - S - - - LURP-one-related
GKAFKPJL_03721 2.6e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
GKAFKPJL_03722 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
GKAFKPJL_03723 4.59e-257 - - - T - - - Signal transduction histidine kinase
GKAFKPJL_03724 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
GKAFKPJL_03725 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
GKAFKPJL_03726 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
GKAFKPJL_03727 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKAFKPJL_03728 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GKAFKPJL_03729 3.89e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
GKAFKPJL_03730 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
GKAFKPJL_03731 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
GKAFKPJL_03733 0.0 - - - O - - - Peptidase family M48
GKAFKPJL_03734 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
GKAFKPJL_03735 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
GKAFKPJL_03736 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
GKAFKPJL_03737 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
GKAFKPJL_03738 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
GKAFKPJL_03739 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKAFKPJL_03740 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
GKAFKPJL_03741 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
GKAFKPJL_03742 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
GKAFKPJL_03743 1.75e-43 - - - - - - - -
GKAFKPJL_03744 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
GKAFKPJL_03745 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_03746 8.58e-174 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GKAFKPJL_03747 3.23e-270 yxlH - - EGP - - - Major Facilitator Superfamily
GKAFKPJL_03748 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
GKAFKPJL_03749 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
GKAFKPJL_03750 8.94e-28 yxzF - - - - - - -
GKAFKPJL_03751 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
GKAFKPJL_03752 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
GKAFKPJL_03753 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKAFKPJL_03754 4.54e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_03755 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GKAFKPJL_03756 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
GKAFKPJL_03757 8e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
GKAFKPJL_03758 8.26e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKAFKPJL_03759 1.61e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_03760 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
GKAFKPJL_03761 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_03762 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
GKAFKPJL_03763 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
GKAFKPJL_03764 5.61e-165 - - - EGP - - - Permeases of the major facilitator superfamily
GKAFKPJL_03765 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
GKAFKPJL_03766 4.38e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
GKAFKPJL_03767 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
GKAFKPJL_03768 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKAFKPJL_03769 4.18e-113 ywaE - - K - - - Transcriptional regulator
GKAFKPJL_03770 1.66e-156 ywaF - - S - - - Integral membrane protein
GKAFKPJL_03771 4.41e-215 gspA - - M - - - General stress
GKAFKPJL_03772 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKAFKPJL_03773 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_03774 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_03775 5.24e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKAFKPJL_03776 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
GKAFKPJL_03777 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
GKAFKPJL_03778 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
GKAFKPJL_03779 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
GKAFKPJL_03780 1.21e-143 ywbG - - M - - - effector of murein hydrolase
GKAFKPJL_03781 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GKAFKPJL_03782 2.7e-203 ywbI - - K - - - Transcriptional regulator
GKAFKPJL_03783 3.79e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GKAFKPJL_03784 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GKAFKPJL_03785 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
GKAFKPJL_03786 1.7e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
GKAFKPJL_03787 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
GKAFKPJL_03788 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
GKAFKPJL_03789 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKAFKPJL_03790 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
GKAFKPJL_03792 4.16e-159 ywcC - - K - - - transcriptional regulator
GKAFKPJL_03793 3.33e-77 gtcA - - S - - - GtrA-like protein
GKAFKPJL_03794 2.27e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKAFKPJL_03795 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
GKAFKPJL_03796 5.11e-49 ydaS - - S - - - membrane
GKAFKPJL_03797 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GKAFKPJL_03798 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GKAFKPJL_03799 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GKAFKPJL_03800 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
GKAFKPJL_03801 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
GKAFKPJL_03802 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
GKAFKPJL_03803 5.44e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
GKAFKPJL_03804 1.99e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKAFKPJL_03805 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
GKAFKPJL_03807 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
GKAFKPJL_03808 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
GKAFKPJL_03809 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_03810 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
GKAFKPJL_03811 6.19e-39 ywdA - - - - - - -
GKAFKPJL_03812 7.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
GKAFKPJL_03813 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
GKAFKPJL_03814 8.74e-146 ywdD - - - - - - -
GKAFKPJL_03816 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
GKAFKPJL_03817 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKAFKPJL_03818 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
GKAFKPJL_03819 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
GKAFKPJL_03820 1.86e-303 ywdJ - - F - - - Xanthine uracil
GKAFKPJL_03821 1.59e-78 ywdK - - S - - - small membrane protein
GKAFKPJL_03822 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GKAFKPJL_03823 2.32e-186 spsA - - M - - - Spore Coat
GKAFKPJL_03824 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
GKAFKPJL_03825 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
GKAFKPJL_03826 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
GKAFKPJL_03827 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
GKAFKPJL_03828 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
GKAFKPJL_03829 2.54e-243 spsG - - M - - - Spore Coat
GKAFKPJL_03830 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKAFKPJL_03831 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKAFKPJL_03832 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKAFKPJL_03833 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
GKAFKPJL_03834 1.1e-102 - - - - - - - -
GKAFKPJL_03835 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
GKAFKPJL_03836 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
GKAFKPJL_03837 0.0 rocB - - E - - - arginine degradation protein
GKAFKPJL_03838 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
GKAFKPJL_03839 1.09e-274 ywfA - - EGP - - - -transporter
GKAFKPJL_03840 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GKAFKPJL_03841 7.2e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GKAFKPJL_03842 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GKAFKPJL_03843 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
GKAFKPJL_03844 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKAFKPJL_03845 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
GKAFKPJL_03846 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_03847 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKAFKPJL_03848 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
GKAFKPJL_03849 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
GKAFKPJL_03850 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
GKAFKPJL_03852 6.34e-228 ykvZ - - K - - - Transcriptional regulator
GKAFKPJL_03853 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
GKAFKPJL_03854 3.99e-09 - - - - - - - -
GKAFKPJL_03855 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
GKAFKPJL_03856 1.31e-113 stoA - - CO - - - thiol-disulfide
GKAFKPJL_03857 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_03858 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
GKAFKPJL_03859 2.5e-39 - - - - - - - -
GKAFKPJL_03860 5.43e-35 ykvS - - S - - - protein conserved in bacteria
GKAFKPJL_03861 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
GKAFKPJL_03862 2.04e-203 - - - G - - - Glycosyl hydrolases family 18
GKAFKPJL_03863 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
GKAFKPJL_03864 1.82e-273 - - - M - - - Glycosyl transferases group 1
GKAFKPJL_03865 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_03866 2.8e-81 ykvN - - K - - - Transcriptional regulator
GKAFKPJL_03867 1.37e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GKAFKPJL_03868 8.4e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GKAFKPJL_03869 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
GKAFKPJL_03870 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GKAFKPJL_03871 2.36e-227 ykvI - - S - - - membrane
GKAFKPJL_03872 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
GKAFKPJL_03873 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
GKAFKPJL_03874 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
GKAFKPJL_03875 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
GKAFKPJL_03876 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
GKAFKPJL_03877 5.62e-93 eag - - - - - - -
GKAFKPJL_03879 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
GKAFKPJL_03880 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKAFKPJL_03881 1.81e-41 yazB - - K - - - transcriptional
GKAFKPJL_03882 9.21e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GKAFKPJL_03883 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKAFKPJL_03884 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKAFKPJL_03885 1.6e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
GKAFKPJL_03886 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
GKAFKPJL_03887 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKAFKPJL_03888 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
GKAFKPJL_03889 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
GKAFKPJL_03890 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKAFKPJL_03891 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GKAFKPJL_03892 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKAFKPJL_03893 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
GKAFKPJL_03894 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKAFKPJL_03895 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
GKAFKPJL_03896 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
GKAFKPJL_03897 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
GKAFKPJL_03900 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
GKAFKPJL_03901 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
GKAFKPJL_03902 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
GKAFKPJL_03903 1.91e-66 yabP - - S - - - Sporulation protein YabP
GKAFKPJL_03904 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GKAFKPJL_03905 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GKAFKPJL_03906 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GKAFKPJL_03907 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
GKAFKPJL_03908 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKAFKPJL_03909 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
GKAFKPJL_03910 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKAFKPJL_03911 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GKAFKPJL_03912 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKAFKPJL_03913 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKAFKPJL_03914 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GKAFKPJL_03915 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
GKAFKPJL_03916 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
GKAFKPJL_03917 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKAFKPJL_03918 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
GKAFKPJL_03919 5.32e-53 veg - - S - - - protein conserved in bacteria
GKAFKPJL_03920 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
GKAFKPJL_03921 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKAFKPJL_03922 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKAFKPJL_03923 1.18e-277 yabE - - T - - - protein conserved in bacteria
GKAFKPJL_03924 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
GKAFKPJL_03925 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKAFKPJL_03926 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
GKAFKPJL_03927 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKAFKPJL_03928 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
GKAFKPJL_03929 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
GKAFKPJL_03930 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
GKAFKPJL_03931 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
GKAFKPJL_03932 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
GKAFKPJL_03933 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
GKAFKPJL_03934 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
GKAFKPJL_03935 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKAFKPJL_03936 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
GKAFKPJL_03937 8.37e-259 yaaN - - P - - - Belongs to the TelA family
GKAFKPJL_03938 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GKAFKPJL_03939 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
GKAFKPJL_03940 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
GKAFKPJL_03941 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
GKAFKPJL_03942 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
GKAFKPJL_03943 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKAFKPJL_03944 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GKAFKPJL_03945 7.24e-45 yoaF - - - - - - -
GKAFKPJL_03948 1.46e-19 - - - - - - - -
GKAFKPJL_03949 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
GKAFKPJL_03950 6.22e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
GKAFKPJL_03951 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
GKAFKPJL_03952 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
GKAFKPJL_03953 1.79e-145 yoaK - - S - - - Membrane
GKAFKPJL_03954 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
GKAFKPJL_03955 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
GKAFKPJL_03957 7.68e-180 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
GKAFKPJL_03958 5.22e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
GKAFKPJL_03959 9.47e-202 - - - K - - - Transcriptional regulator
GKAFKPJL_03960 1.41e-215 yrdR - - EG - - - EamA-like transporter family
GKAFKPJL_03961 2.45e-23 - - - S - - - YrzO-like protein
GKAFKPJL_03962 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
GKAFKPJL_03963 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
GKAFKPJL_03964 7.59e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_03965 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
GKAFKPJL_03966 1.82e-137 yrkC - - G - - - Cupin domain
GKAFKPJL_03967 4.38e-52 yrkD - - S - - - protein conserved in bacteria
GKAFKPJL_03968 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
GKAFKPJL_03969 9.3e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
GKAFKPJL_03970 2.16e-265 yrkH - - P - - - Rhodanese Homology Domain
GKAFKPJL_03971 2.63e-48 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
GKAFKPJL_03972 3.14e-160 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
GKAFKPJL_03973 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
GKAFKPJL_03974 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
GKAFKPJL_03975 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
GKAFKPJL_03976 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
GKAFKPJL_03977 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
GKAFKPJL_03978 7.32e-306 yrkQ - - T - - - Histidine kinase
GKAFKPJL_03979 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKAFKPJL_03980 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKAFKPJL_03982 1.82e-267 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
GKAFKPJL_03983 6.12e-20 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
GKAFKPJL_03984 1.28e-102 yffB - - K - - - Transcriptional regulator
GKAFKPJL_03985 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
GKAFKPJL_03986 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
GKAFKPJL_03987 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
GKAFKPJL_03988 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
GKAFKPJL_03989 3.69e-201 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
GKAFKPJL_03990 2.51e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GKAFKPJL_03991 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_03992 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
GKAFKPJL_03993 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
GKAFKPJL_03994 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
GKAFKPJL_03995 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
GKAFKPJL_03996 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
GKAFKPJL_03997 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GKAFKPJL_03998 1.13e-156 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_03999 7.71e-56 - - - E - - - phosphoribosylanthranilate isomerase activity
GKAFKPJL_04000 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
GKAFKPJL_04001 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
GKAFKPJL_04002 5.85e-274 xylR - - GK - - - ROK family
GKAFKPJL_04003 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
GKAFKPJL_04004 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
GKAFKPJL_04005 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
GKAFKPJL_04006 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
GKAFKPJL_04007 1.77e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKAFKPJL_04008 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
GKAFKPJL_04009 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
GKAFKPJL_04010 7.54e-22 - - - - - - - -
GKAFKPJL_04013 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKAFKPJL_04015 4.44e-172 - - - S - - - Domain of unknown function, YrpD
GKAFKPJL_04018 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
GKAFKPJL_04019 8.92e-96 - - - - - - - -
GKAFKPJL_04020 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
GKAFKPJL_04023 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
GKAFKPJL_04024 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
GKAFKPJL_04025 5.57e-289 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
GKAFKPJL_04026 1.85e-198 yndG - - S - - - DoxX-like family
GKAFKPJL_04027 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
GKAFKPJL_04028 0.0 yndJ - - S - - - YndJ-like protein
GKAFKPJL_04030 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
GKAFKPJL_04031 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
GKAFKPJL_04032 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_04033 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKAFKPJL_04034 1.05e-22 - - - - - - - -
GKAFKPJL_04035 2.02e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
GKAFKPJL_04036 3.71e-110 ykyB - - S - - - YkyB-like protein
GKAFKPJL_04037 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
GKAFKPJL_04038 5.84e-115 ykuD - - S - - - protein conserved in bacteria
GKAFKPJL_04039 9.97e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
GKAFKPJL_04040 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GKAFKPJL_04041 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
GKAFKPJL_04042 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
GKAFKPJL_04043 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
GKAFKPJL_04044 7.83e-38 ykzF - - S - - - Antirepressor AbbA
GKAFKPJL_04045 5.15e-100 ykuL - - S - - - CBS domain
GKAFKPJL_04046 6.52e-216 ccpC - - K - - - Transcriptional regulator
GKAFKPJL_04047 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
GKAFKPJL_04048 7.7e-226 ykuO - - - - - - -
GKAFKPJL_04049 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
GKAFKPJL_04050 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKAFKPJL_04051 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKAFKPJL_04052 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
GKAFKPJL_04053 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
GKAFKPJL_04054 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
GKAFKPJL_04055 1.47e-104 ykuV - - CO - - - thiol-disulfide
GKAFKPJL_04056 4.71e-122 rok - - K - - - Repressor of ComK
GKAFKPJL_04057 2.43e-200 yknT - - - ko:K06437 - ko00000 -
GKAFKPJL_04058 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GKAFKPJL_04059 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GKAFKPJL_04060 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
GKAFKPJL_04061 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
GKAFKPJL_04062 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
GKAFKPJL_04063 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GKAFKPJL_04064 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKAFKPJL_04065 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
GKAFKPJL_04066 5.34e-150 yknW - - S - - - Yip1 domain
GKAFKPJL_04067 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKAFKPJL_04068 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
GKAFKPJL_04069 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
GKAFKPJL_04070 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
GKAFKPJL_04071 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
GKAFKPJL_04072 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GKAFKPJL_04073 4.29e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
GKAFKPJL_04074 5.43e-166 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
GKAFKPJL_04075 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
GKAFKPJL_04076 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKAFKPJL_04077 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
GKAFKPJL_04080 4.18e-14 - - - - - - - -
GKAFKPJL_04083 1.04e-42 - - - S - - - Terminase
GKAFKPJL_04084 6.85e-103 - - - L - - - phage terminase small subunit
GKAFKPJL_04085 1.09e-62 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
GKAFKPJL_04088 1.14e-61 ynaF - - - - - - -
GKAFKPJL_04089 1.1e-142 - - - S - - - Domain of unknown function (DUF3885)
GKAFKPJL_04090 2.79e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
GKAFKPJL_04091 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
GKAFKPJL_04092 3.45e-90 - - - S - - - CAAX protease self-immunity
GKAFKPJL_04094 7.11e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
GKAFKPJL_04096 3.49e-271 - - - H - - - N-terminal domain of galactosyltransferase
GKAFKPJL_04097 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
GKAFKPJL_04098 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
GKAFKPJL_04099 9.6e-120 - - - M - - - Glycosyltransferase like family
GKAFKPJL_04100 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
GKAFKPJL_04101 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GKAFKPJL_04102 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
GKAFKPJL_04103 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
GKAFKPJL_04104 1.37e-30 - - - S - - - YtkA-like
GKAFKPJL_04105 9e-62 - - - S - - - PepSY-associated TM region
GKAFKPJL_04106 1.69e-142 - - - S - - - PepSY-associated TM region
GKAFKPJL_04107 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
GKAFKPJL_04108 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
GKAFKPJL_04109 1.41e-61 - - - - - - - -
GKAFKPJL_04110 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
GKAFKPJL_04111 4.35e-53 - - - S - - - Spore coat protein Z
GKAFKPJL_04112 1.14e-117 - - - S - - - Tetratricopeptide repeat
GKAFKPJL_04115 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
GKAFKPJL_04116 2.14e-232 yaaC - - S - - - YaaC-like Protein
GKAFKPJL_04117 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GKAFKPJL_04118 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
GKAFKPJL_04119 1.06e-201 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GKAFKPJL_04120 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GKAFKPJL_04121 2.3e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKAFKPJL_04123 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
GKAFKPJL_04124 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
GKAFKPJL_04125 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
GKAFKPJL_04126 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
GKAFKPJL_04127 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKAFKPJL_04128 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKAFKPJL_04129 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKAFKPJL_04130 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKAFKPJL_04131 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
GKAFKPJL_04132 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
GKAFKPJL_04133 4.81e-40 - - - S - - - Protein of unknown function (DUF1232)
GKAFKPJL_04134 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GKAFKPJL_04135 1.51e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GKAFKPJL_04136 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GKAFKPJL_04137 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GKAFKPJL_04138 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
GKAFKPJL_04139 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GKAFKPJL_04140 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GKAFKPJL_04141 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GKAFKPJL_04143 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKAFKPJL_04144 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
GKAFKPJL_04145 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
GKAFKPJL_04146 1.77e-28 ykzE - - - - - - -
GKAFKPJL_04148 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
GKAFKPJL_04149 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
GKAFKPJL_04150 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
GKAFKPJL_04151 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
GKAFKPJL_04152 9.67e-183 rsgI - - S - - - Anti-sigma factor N-terminus
GKAFKPJL_04163 2.34e-152 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
GKAFKPJL_04173 2.94e-141 pksA - - K - - - Transcriptional regulator
GKAFKPJL_04174 6.55e-126 ymcC - - S - - - Membrane

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)