ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EFPMHGIB_00003 4.18e-14 - - - - - - - -
EFPMHGIB_00006 1.04e-42 - - - S - - - Terminase
EFPMHGIB_00007 6.85e-103 - - - L - - - phage terminase small subunit
EFPMHGIB_00008 1.89e-63 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
EFPMHGIB_00013 4.25e-25 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
EFPMHGIB_00014 1.4e-86 - - - S - - - regulation of transcription, DNA-dependent
EFPMHGIB_00015 1.82e-31 - - - S - - - FRG
EFPMHGIB_00016 4.9e-66 - - - M - - - ArpU family transcriptional regulator
EFPMHGIB_00019 3.5e-30 - - - - - - - -
EFPMHGIB_00020 9.44e-127 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
EFPMHGIB_00021 4.61e-47 - - - L - - - Arm DNA-binding domain
EFPMHGIB_00022 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EFPMHGIB_00023 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EFPMHGIB_00024 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EFPMHGIB_00025 2.12e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFPMHGIB_00026 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EFPMHGIB_00027 9.08e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EFPMHGIB_00028 2.24e-141 - - - - - - - -
EFPMHGIB_00029 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFPMHGIB_00030 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFPMHGIB_00031 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EFPMHGIB_00032 1.2e-30 ymzA - - - - - - -
EFPMHGIB_00033 1.63e-31 - - - - - - - -
EFPMHGIB_00034 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EFPMHGIB_00035 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFPMHGIB_00036 5.41e-76 ymaF - - S - - - YmaF family
EFPMHGIB_00038 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EFPMHGIB_00039 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
EFPMHGIB_00040 1.47e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EFPMHGIB_00041 3.96e-163 ymaC - - S - - - Replication protein
EFPMHGIB_00043 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EFPMHGIB_00044 1.09e-206 - - - S - - - Metallo-beta-lactamase superfamily
EFPMHGIB_00045 3.27e-80 ymzB - - - - - - -
EFPMHGIB_00046 8.33e-296 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EFPMHGIB_00047 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EFPMHGIB_00048 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EFPMHGIB_00049 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EFPMHGIB_00050 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EFPMHGIB_00051 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EFPMHGIB_00052 4.29e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EFPMHGIB_00053 2.04e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EFPMHGIB_00054 2.78e-313 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EFPMHGIB_00055 1.78e-302 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFPMHGIB_00056 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EFPMHGIB_00057 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EFPMHGIB_00058 3.17e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EFPMHGIB_00061 2.17e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EFPMHGIB_00062 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EFPMHGIB_00063 3.43e-140 pksA - - K - - - Transcriptional regulator
EFPMHGIB_00064 1.38e-127 ymcC - - S - - - Membrane
EFPMHGIB_00065 6.68e-92 - - - S - - - Regulatory protein YrvL
EFPMHGIB_00066 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFPMHGIB_00067 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFPMHGIB_00068 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
EFPMHGIB_00069 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EFPMHGIB_00070 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EFPMHGIB_00071 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EFPMHGIB_00072 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EFPMHGIB_00073 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EFPMHGIB_00074 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EFPMHGIB_00075 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EFPMHGIB_00076 8.43e-282 pbpX - - V - - - Beta-lactamase
EFPMHGIB_00077 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFPMHGIB_00078 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EFPMHGIB_00079 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFPMHGIB_00080 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EFPMHGIB_00081 5.56e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
EFPMHGIB_00082 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
EFPMHGIB_00083 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EFPMHGIB_00084 6.8e-309 ymfH - - S - - - zinc protease
EFPMHGIB_00085 1.35e-298 albE - - S - - - Peptidase M16
EFPMHGIB_00086 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_00087 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00088 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EFPMHGIB_00089 4.94e-44 - - - S - - - YlzJ-like protein
EFPMHGIB_00090 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EFPMHGIB_00091 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFPMHGIB_00092 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFPMHGIB_00093 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EFPMHGIB_00094 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFPMHGIB_00095 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EFPMHGIB_00096 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EFPMHGIB_00097 1.53e-56 ymxH - - S - - - YlmC YmxH family
EFPMHGIB_00098 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
EFPMHGIB_00099 2.92e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EFPMHGIB_00100 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EFPMHGIB_00101 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFPMHGIB_00102 1.34e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EFPMHGIB_00103 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFPMHGIB_00104 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFPMHGIB_00105 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EFPMHGIB_00106 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFPMHGIB_00107 6.16e-63 ylxQ - - J - - - ribosomal protein
EFPMHGIB_00108 5.78e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EFPMHGIB_00109 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EFPMHGIB_00110 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EFPMHGIB_00111 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFPMHGIB_00112 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EFPMHGIB_00113 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EFPMHGIB_00114 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EFPMHGIB_00115 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EFPMHGIB_00116 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFPMHGIB_00117 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EFPMHGIB_00118 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EFPMHGIB_00119 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFPMHGIB_00120 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EFPMHGIB_00121 6.62e-99 ylxL - - - - - - -
EFPMHGIB_00122 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_00123 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EFPMHGIB_00124 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EFPMHGIB_00125 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EFPMHGIB_00126 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EFPMHGIB_00127 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EFPMHGIB_00128 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EFPMHGIB_00129 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EFPMHGIB_00130 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EFPMHGIB_00131 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EFPMHGIB_00132 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EFPMHGIB_00133 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EFPMHGIB_00134 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EFPMHGIB_00135 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EFPMHGIB_00136 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EFPMHGIB_00137 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EFPMHGIB_00138 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EFPMHGIB_00139 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EFPMHGIB_00140 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EFPMHGIB_00141 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EFPMHGIB_00142 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EFPMHGIB_00143 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
EFPMHGIB_00144 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EFPMHGIB_00145 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EFPMHGIB_00146 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EFPMHGIB_00147 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EFPMHGIB_00148 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EFPMHGIB_00149 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EFPMHGIB_00150 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EFPMHGIB_00151 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EFPMHGIB_00152 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EFPMHGIB_00153 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EFPMHGIB_00154 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EFPMHGIB_00155 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EFPMHGIB_00156 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EFPMHGIB_00157 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFPMHGIB_00158 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EFPMHGIB_00159 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EFPMHGIB_00160 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EFPMHGIB_00161 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EFPMHGIB_00162 0.0 ylqG - - - - - - -
EFPMHGIB_00163 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFPMHGIB_00164 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFPMHGIB_00165 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EFPMHGIB_00166 6.9e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EFPMHGIB_00167 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFPMHGIB_00168 9.77e-80 ylqD - - S - - - YlqD protein
EFPMHGIB_00169 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EFPMHGIB_00170 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EFPMHGIB_00171 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFPMHGIB_00172 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFPMHGIB_00173 1.67e-114 - - - - - - - -
EFPMHGIB_00174 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFPMHGIB_00175 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EFPMHGIB_00176 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EFPMHGIB_00177 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFPMHGIB_00178 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EFPMHGIB_00179 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EFPMHGIB_00180 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EFPMHGIB_00181 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EFPMHGIB_00182 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFPMHGIB_00183 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EFPMHGIB_00184 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EFPMHGIB_00185 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EFPMHGIB_00186 3.65e-78 yloU - - S - - - protein conserved in bacteria
EFPMHGIB_00187 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EFPMHGIB_00188 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EFPMHGIB_00189 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EFPMHGIB_00190 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EFPMHGIB_00191 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EFPMHGIB_00192 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EFPMHGIB_00193 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EFPMHGIB_00194 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFPMHGIB_00195 5.2e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFPMHGIB_00196 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFPMHGIB_00197 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFPMHGIB_00198 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFPMHGIB_00199 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EFPMHGIB_00200 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EFPMHGIB_00201 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EFPMHGIB_00202 8.41e-202 yloC - - S - - - stress-induced protein
EFPMHGIB_00203 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EFPMHGIB_00204 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EFPMHGIB_00205 1.08e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EFPMHGIB_00206 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EFPMHGIB_00207 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EFPMHGIB_00208 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EFPMHGIB_00209 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EFPMHGIB_00210 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EFPMHGIB_00211 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EFPMHGIB_00213 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EFPMHGIB_00214 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EFPMHGIB_00215 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EFPMHGIB_00216 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EFPMHGIB_00217 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EFPMHGIB_00218 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EFPMHGIB_00219 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EFPMHGIB_00220 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EFPMHGIB_00221 3.71e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EFPMHGIB_00222 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EFPMHGIB_00223 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EFPMHGIB_00224 5.47e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFPMHGIB_00225 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
EFPMHGIB_00226 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFPMHGIB_00227 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EFPMHGIB_00228 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
EFPMHGIB_00229 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EFPMHGIB_00230 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EFPMHGIB_00231 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFPMHGIB_00232 7.23e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EFPMHGIB_00233 3.58e-51 ylmC - - S - - - sporulation protein
EFPMHGIB_00234 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EFPMHGIB_00235 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EFPMHGIB_00236 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_00237 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_00238 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EFPMHGIB_00240 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EFPMHGIB_00241 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFPMHGIB_00242 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EFPMHGIB_00243 5.37e-76 sbp - - S - - - small basic protein
EFPMHGIB_00244 1.03e-123 ylxX - - S - - - protein conserved in bacteria
EFPMHGIB_00245 4.5e-142 ylxW - - S - - - protein conserved in bacteria
EFPMHGIB_00246 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EFPMHGIB_00247 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EFPMHGIB_00248 2.69e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFPMHGIB_00249 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EFPMHGIB_00250 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFPMHGIB_00251 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFPMHGIB_00252 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFPMHGIB_00253 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EFPMHGIB_00254 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EFPMHGIB_00255 3.42e-68 ftsL - - D - - - Essential cell division protein
EFPMHGIB_00256 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EFPMHGIB_00257 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EFPMHGIB_00258 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EFPMHGIB_00259 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFPMHGIB_00260 1.33e-115 ylbP - - K - - - n-acetyltransferase
EFPMHGIB_00261 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EFPMHGIB_00262 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EFPMHGIB_00263 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EFPMHGIB_00265 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
EFPMHGIB_00266 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EFPMHGIB_00267 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EFPMHGIB_00268 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EFPMHGIB_00269 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFPMHGIB_00270 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EFPMHGIB_00271 8.8e-52 ylbG - - S - - - UPF0298 protein
EFPMHGIB_00272 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
EFPMHGIB_00273 1.73e-48 ylbE - - S - - - YlbE-like protein
EFPMHGIB_00274 3.24e-89 ylbD - - S - - - Putative coat protein
EFPMHGIB_00275 1.08e-256 ylbC - - S - - - protein with SCP PR1 domains
EFPMHGIB_00276 4.39e-97 ylbB - - T - - - COG0517 FOG CBS domain
EFPMHGIB_00277 1.61e-81 ylbA - - S - - - YugN-like family
EFPMHGIB_00278 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EFPMHGIB_00279 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EFPMHGIB_00280 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EFPMHGIB_00281 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EFPMHGIB_00282 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EFPMHGIB_00283 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EFPMHGIB_00284 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EFPMHGIB_00285 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EFPMHGIB_00286 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EFPMHGIB_00287 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
EFPMHGIB_00288 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EFPMHGIB_00289 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EFPMHGIB_00290 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EFPMHGIB_00291 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFPMHGIB_00292 8.92e-44 ylaI - - S - - - protein conserved in bacteria
EFPMHGIB_00293 4.4e-63 ylaH - - S - - - YlaH-like protein
EFPMHGIB_00294 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EFPMHGIB_00295 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
EFPMHGIB_00296 1.74e-57 ylaE - - - - - - -
EFPMHGIB_00298 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_00299 1.44e-56 ylaB - - - - - - -
EFPMHGIB_00300 0.0 ylaA - - - - - - -
EFPMHGIB_00301 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EFPMHGIB_00302 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EFPMHGIB_00303 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
EFPMHGIB_00304 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EFPMHGIB_00305 2.03e-35 ykzI - - - - - - -
EFPMHGIB_00306 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
EFPMHGIB_00307 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
EFPMHGIB_00308 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EFPMHGIB_00309 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EFPMHGIB_00310 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFPMHGIB_00311 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFPMHGIB_00312 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFPMHGIB_00313 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFPMHGIB_00314 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
EFPMHGIB_00315 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EFPMHGIB_00316 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFPMHGIB_00317 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
EFPMHGIB_00318 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
EFPMHGIB_00319 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFPMHGIB_00320 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EFPMHGIB_00321 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EFPMHGIB_00322 3.42e-198 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EFPMHGIB_00323 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EFPMHGIB_00324 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EFPMHGIB_00325 3.57e-233 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EFPMHGIB_00326 1.09e-18 - - - S - - - Uncharacterized protein YkpC
EFPMHGIB_00327 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EFPMHGIB_00328 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFPMHGIB_00329 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFPMHGIB_00330 5.43e-52 ykoA - - - - - - -
EFPMHGIB_00331 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EFPMHGIB_00332 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EFPMHGIB_00333 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EFPMHGIB_00334 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00335 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EFPMHGIB_00336 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_00337 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFPMHGIB_00338 5.34e-150 yknW - - S - - - Yip1 domain
EFPMHGIB_00339 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EFPMHGIB_00340 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EFPMHGIB_00341 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EFPMHGIB_00342 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EFPMHGIB_00343 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EFPMHGIB_00344 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EFPMHGIB_00345 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFPMHGIB_00346 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EFPMHGIB_00347 2.43e-200 yknT - - - ko:K06437 - ko00000 -
EFPMHGIB_00348 4.71e-122 rok - - K - - - Repressor of ComK
EFPMHGIB_00349 1.47e-104 ykuV - - CO - - - thiol-disulfide
EFPMHGIB_00350 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
EFPMHGIB_00351 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EFPMHGIB_00352 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
EFPMHGIB_00353 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EFPMHGIB_00354 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EFPMHGIB_00355 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
EFPMHGIB_00356 7.7e-226 ykuO - - - - - - -
EFPMHGIB_00357 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
EFPMHGIB_00358 6.52e-216 ccpC - - K - - - Transcriptional regulator
EFPMHGIB_00359 5.15e-100 ykuL - - S - - - CBS domain
EFPMHGIB_00360 7.83e-38 ykzF - - S - - - Antirepressor AbbA
EFPMHGIB_00361 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
EFPMHGIB_00362 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
EFPMHGIB_00363 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
EFPMHGIB_00364 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_00365 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EFPMHGIB_00366 5.84e-115 ykuD - - S - - - protein conserved in bacteria
EFPMHGIB_00367 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_00368 3.71e-110 ykyB - - S - - - YkyB-like protein
EFPMHGIB_00369 2.02e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EFPMHGIB_00370 1.05e-22 - - - - - - - -
EFPMHGIB_00371 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFPMHGIB_00372 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_00373 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EFPMHGIB_00374 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
EFPMHGIB_00375 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EFPMHGIB_00376 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_00377 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_00378 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EFPMHGIB_00379 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00380 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFPMHGIB_00381 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EFPMHGIB_00382 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_00383 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EFPMHGIB_00385 6.34e-228 ykvZ - - K - - - Transcriptional regulator
EFPMHGIB_00386 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EFPMHGIB_00387 3.99e-09 - - - - - - - -
EFPMHGIB_00388 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EFPMHGIB_00389 1.12e-114 stoA - - CO - - - thiol-disulfide
EFPMHGIB_00390 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_00391 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EFPMHGIB_00392 2.6e-39 - - - - - - - -
EFPMHGIB_00393 5.43e-35 ykvS - - S - - - protein conserved in bacteria
EFPMHGIB_00394 3.12e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
EFPMHGIB_00395 3.53e-204 - - - G - - - Glycosyl hydrolases family 18
EFPMHGIB_00396 2.87e-43 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
EFPMHGIB_00397 2.58e-273 - - - M - - - Glycosyl transferases group 1
EFPMHGIB_00398 2.11e-169 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_00399 4.98e-78 - - - K - - - HxlR-like helix-turn-helix
EFPMHGIB_00400 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EFPMHGIB_00401 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EFPMHGIB_00402 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EFPMHGIB_00403 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EFPMHGIB_00404 6.76e-227 ykvI - - S - - - membrane
EFPMHGIB_00405 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EFPMHGIB_00406 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EFPMHGIB_00407 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EFPMHGIB_00408 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EFPMHGIB_00409 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EFPMHGIB_00410 1.18e-94 eag - - - - - - -
EFPMHGIB_00412 3.6e-67 - - - S - - - Protein of unknown function (DUF1232)
EFPMHGIB_00413 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EFPMHGIB_00414 2.61e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EFPMHGIB_00415 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EFPMHGIB_00416 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EFPMHGIB_00417 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EFPMHGIB_00418 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFPMHGIB_00419 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EFPMHGIB_00420 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EFPMHGIB_00422 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFPMHGIB_00423 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_00424 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EFPMHGIB_00425 1.77e-28 ykzE - - - - - - -
EFPMHGIB_00427 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EFPMHGIB_00428 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EFPMHGIB_00429 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
EFPMHGIB_00430 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EFPMHGIB_00431 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
EFPMHGIB_00432 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_00433 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EFPMHGIB_00434 1.71e-143 ykoX - - S - - - membrane-associated protein
EFPMHGIB_00435 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
EFPMHGIB_00436 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EFPMHGIB_00437 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EFPMHGIB_00438 2.23e-236 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_00439 0.0 ykoS - - - - - - -
EFPMHGIB_00440 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EFPMHGIB_00441 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
EFPMHGIB_00442 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
EFPMHGIB_00443 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EFPMHGIB_00444 3.04e-36 ykoL - - - - - - -
EFPMHGIB_00445 1.63e-25 - - - - - - - -
EFPMHGIB_00446 1.49e-70 tnrA - - K - - - transcriptional
EFPMHGIB_00447 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EFPMHGIB_00449 1.45e-08 - - - - - - - -
EFPMHGIB_00450 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
EFPMHGIB_00451 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
EFPMHGIB_00452 3.5e-306 ykoH - - T - - - Histidine kinase
EFPMHGIB_00453 8.68e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_00454 4.05e-141 ykoF - - S - - - YKOF-related Family
EFPMHGIB_00455 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EFPMHGIB_00456 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_00457 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EFPMHGIB_00458 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFPMHGIB_00459 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_00460 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EFPMHGIB_00461 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
EFPMHGIB_00462 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
EFPMHGIB_00463 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
EFPMHGIB_00464 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
EFPMHGIB_00465 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFPMHGIB_00466 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFPMHGIB_00467 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EFPMHGIB_00468 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EFPMHGIB_00469 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EFPMHGIB_00470 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFPMHGIB_00471 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
EFPMHGIB_00472 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
EFPMHGIB_00473 5.85e-13 - - - - - - - -
EFPMHGIB_00474 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EFPMHGIB_00475 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
EFPMHGIB_00476 4.37e-206 ykgA - - E - - - Amidinotransferase
EFPMHGIB_00477 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EFPMHGIB_00478 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00479 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EFPMHGIB_00480 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EFPMHGIB_00481 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EFPMHGIB_00483 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EFPMHGIB_00484 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00485 9.02e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00486 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00487 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EFPMHGIB_00488 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
EFPMHGIB_00489 1.27e-279 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFPMHGIB_00491 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_00492 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFPMHGIB_00493 9.82e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EFPMHGIB_00494 2.57e-309 steT - - E ko:K03294 - ko00000 amino acid
EFPMHGIB_00495 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EFPMHGIB_00496 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
EFPMHGIB_00497 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EFPMHGIB_00498 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EFPMHGIB_00500 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EFPMHGIB_00501 1.15e-52 xhlB - - S - - - SPP1 phage holin
EFPMHGIB_00502 2.21e-51 xhlA - - S - - - Haemolysin XhlA
EFPMHGIB_00503 2.21e-193 xepA - - - - - - -
EFPMHGIB_00504 6.35e-31 xkdX - - - - - - -
EFPMHGIB_00505 3.67e-59 xkdW - - S - - - XkdW protein
EFPMHGIB_00506 2.88e-221 - - - - - - - -
EFPMHGIB_00507 6.29e-56 - - - - - - - -
EFPMHGIB_00508 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EFPMHGIB_00509 1.79e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EFPMHGIB_00510 7.71e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
EFPMHGIB_00511 1.76e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
EFPMHGIB_00512 2.31e-232 xkdQ - - G - - - NLP P60 protein
EFPMHGIB_00513 8.57e-152 xkdP - - S - - - Lysin motif
EFPMHGIB_00514 0.0 xkdO - - L - - - Transglycosylase SLT domain
EFPMHGIB_00515 3.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EFPMHGIB_00516 6.01e-99 xkdM - - S - - - Phage tail tube protein
EFPMHGIB_00517 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EFPMHGIB_00518 2.36e-100 xkdJ - - - - - - -
EFPMHGIB_00519 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EFPMHGIB_00520 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
EFPMHGIB_00521 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
EFPMHGIB_00522 3.91e-217 xkdG - - S - - - Phage capsid family
EFPMHGIB_00523 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
EFPMHGIB_00524 0.0 yqbA - - S - - - portal protein
EFPMHGIB_00525 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EFPMHGIB_00526 9.65e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EFPMHGIB_00527 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EFPMHGIB_00531 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
EFPMHGIB_00532 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
EFPMHGIB_00534 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
EFPMHGIB_00535 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
EFPMHGIB_00536 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
EFPMHGIB_00537 1.47e-143 yjqB - - S - - - Pfam:DUF867
EFPMHGIB_00538 3.31e-81 yjqA - - S - - - Bacterial PH domain
EFPMHGIB_00539 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EFPMHGIB_00540 1.79e-55 - - - S - - - YCII-related domain
EFPMHGIB_00542 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EFPMHGIB_00543 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
EFPMHGIB_00544 4.87e-106 yjoA - - S - - - DinB family
EFPMHGIB_00545 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EFPMHGIB_00546 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EFPMHGIB_00547 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
EFPMHGIB_00548 8.11e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EFPMHGIB_00549 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
EFPMHGIB_00550 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_00551 7.59e-271 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
EFPMHGIB_00552 5.73e-240 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EFPMHGIB_00553 3.45e-240 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
EFPMHGIB_00554 1.51e-314 - - - G ko:K03292 - ko00000 symporter YjmB
EFPMHGIB_00555 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EFPMHGIB_00556 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EFPMHGIB_00557 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EFPMHGIB_00558 2.36e-116 yjlB - - S - - - Cupin domain
EFPMHGIB_00559 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EFPMHGIB_00560 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EFPMHGIB_00561 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EFPMHGIB_00562 1.23e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EFPMHGIB_00563 1.11e-41 - - - - - - - -
EFPMHGIB_00564 6.88e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EFPMHGIB_00565 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EFPMHGIB_00567 3.7e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EFPMHGIB_00569 2.27e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
EFPMHGIB_00570 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EFPMHGIB_00571 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
EFPMHGIB_00572 5.62e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
EFPMHGIB_00573 7.02e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EFPMHGIB_00574 1.13e-29 yjfB - - S - - - Putative motility protein
EFPMHGIB_00575 3.54e-105 - - - S - - - Protein of unknown function (DUF2690)
EFPMHGIB_00576 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EFPMHGIB_00578 2.16e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EFPMHGIB_00579 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
EFPMHGIB_00580 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
EFPMHGIB_00581 1.12e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFPMHGIB_00583 2.44e-115 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
EFPMHGIB_00584 4.58e-76 yjdF3 - - S - - - Protein of unknown function (DUF2992)
EFPMHGIB_00585 5.95e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EFPMHGIB_00586 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_00587 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EFPMHGIB_00588 0.000388 - - - - - - - -
EFPMHGIB_00589 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_00590 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EFPMHGIB_00591 2.49e-07 - - - - - - - -
EFPMHGIB_00592 3.94e-26 - - - - - - - -
EFPMHGIB_00593 1.92e-47 - - - - - - - -
EFPMHGIB_00594 1.42e-09 - - - S - - - YolD-like protein
EFPMHGIB_00597 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
EFPMHGIB_00599 1.33e-50 - - - - - - - -
EFPMHGIB_00602 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
EFPMHGIB_00603 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EFPMHGIB_00604 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EFPMHGIB_00605 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EFPMHGIB_00606 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EFPMHGIB_00607 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EFPMHGIB_00608 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_00609 6.31e-51 - - - - - - - -
EFPMHGIB_00610 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EFPMHGIB_00611 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
EFPMHGIB_00614 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
EFPMHGIB_00615 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EFPMHGIB_00616 9.3e-32 cotW - - - ko:K06341 - ko00000 -
EFPMHGIB_00617 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EFPMHGIB_00618 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EFPMHGIB_00619 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EFPMHGIB_00620 5.16e-104 yjbX - - S - - - Spore coat protein
EFPMHGIB_00621 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EFPMHGIB_00622 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EFPMHGIB_00623 2.94e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFPMHGIB_00624 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EFPMHGIB_00625 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
EFPMHGIB_00626 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EFPMHGIB_00627 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EFPMHGIB_00628 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EFPMHGIB_00629 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EFPMHGIB_00630 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EFPMHGIB_00631 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EFPMHGIB_00632 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFPMHGIB_00633 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EFPMHGIB_00634 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
EFPMHGIB_00635 7.02e-128 yjbK - - S - - - protein conserved in bacteria
EFPMHGIB_00636 2.19e-123 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFPMHGIB_00637 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EFPMHGIB_00638 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EFPMHGIB_00639 2.68e-28 - - - - - - - -
EFPMHGIB_00640 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EFPMHGIB_00641 1.78e-281 coiA - - S ko:K06198 - ko00000 Competence protein
EFPMHGIB_00642 5.66e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EFPMHGIB_00643 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
EFPMHGIB_00644 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EFPMHGIB_00645 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_00646 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
EFPMHGIB_00647 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00648 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00649 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00650 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00651 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EFPMHGIB_00652 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EFPMHGIB_00653 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
EFPMHGIB_00654 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00655 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFPMHGIB_00656 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EFPMHGIB_00657 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00658 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_00659 9.48e-193 yjaZ - - O - - - Zn-dependent protease
EFPMHGIB_00660 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFPMHGIB_00661 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFPMHGIB_00662 2.67e-38 yjzB - - - - - - -
EFPMHGIB_00663 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EFPMHGIB_00664 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EFPMHGIB_00665 5.41e-134 yjaV - - - - - - -
EFPMHGIB_00666 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
EFPMHGIB_00667 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
EFPMHGIB_00668 2.51e-39 yjzC - - S - - - YjzC-like protein
EFPMHGIB_00669 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFPMHGIB_00670 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EFPMHGIB_00671 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EFPMHGIB_00672 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EFPMHGIB_00673 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EFPMHGIB_00674 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EFPMHGIB_00675 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EFPMHGIB_00676 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
EFPMHGIB_00677 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EFPMHGIB_00678 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
EFPMHGIB_00679 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EFPMHGIB_00680 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EFPMHGIB_00681 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EFPMHGIB_00682 1.92e-08 - - - - - - - -
EFPMHGIB_00683 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
EFPMHGIB_00684 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
EFPMHGIB_00685 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EFPMHGIB_00686 3.72e-201 yitS - - S - - - protein conserved in bacteria
EFPMHGIB_00687 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EFPMHGIB_00688 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
EFPMHGIB_00689 6.11e-120 - - - - - - - -
EFPMHGIB_00690 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
EFPMHGIB_00691 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
EFPMHGIB_00692 1.42e-218 - - - - - - - -
EFPMHGIB_00693 4.16e-122 - - - - - - - -
EFPMHGIB_00694 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EFPMHGIB_00695 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EFPMHGIB_00696 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EFPMHGIB_00697 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
EFPMHGIB_00698 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
EFPMHGIB_00699 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_00700 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EFPMHGIB_00701 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFPMHGIB_00702 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
EFPMHGIB_00703 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
EFPMHGIB_00704 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EFPMHGIB_00705 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EFPMHGIB_00706 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EFPMHGIB_00707 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFPMHGIB_00708 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
EFPMHGIB_00709 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_00710 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EFPMHGIB_00711 9.94e-120 yisT - - S - - - DinB family
EFPMHGIB_00712 4.25e-248 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EFPMHGIB_00713 2.14e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EFPMHGIB_00714 1.41e-207 yisR - - K - - - Transcriptional regulator
EFPMHGIB_00715 2.91e-310 yisQ - - V - - - Mate efflux family protein
EFPMHGIB_00716 9.29e-191 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EFPMHGIB_00717 2.53e-113 yizA - - S - - - Damage-inducible protein DinB
EFPMHGIB_00718 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EFPMHGIB_00719 1.82e-132 yisN - - S - - - Protein of unknown function (DUF2777)
EFPMHGIB_00720 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_00721 2.05e-74 yisL - - S - - - UPF0344 protein
EFPMHGIB_00722 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EFPMHGIB_00723 2.11e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
EFPMHGIB_00724 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
EFPMHGIB_00725 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EFPMHGIB_00726 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
EFPMHGIB_00727 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EFPMHGIB_00728 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EFPMHGIB_00729 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EFPMHGIB_00730 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EFPMHGIB_00731 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
EFPMHGIB_00732 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EFPMHGIB_00733 1.63e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EFPMHGIB_00734 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EFPMHGIB_00735 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EFPMHGIB_00736 9.3e-102 yhjR - - S - - - Rubrerythrin
EFPMHGIB_00737 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
EFPMHGIB_00738 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
EFPMHGIB_00739 1.04e-271 - - - EGP - - - Transmembrane secretion effector
EFPMHGIB_00740 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
EFPMHGIB_00741 1.77e-238 yhjM - - K - - - Transcriptional regulator
EFPMHGIB_00742 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EFPMHGIB_00743 1.25e-203 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
EFPMHGIB_00744 7.71e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EFPMHGIB_00745 2.46e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EFPMHGIB_00746 3.29e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_00747 0.0 yhjG - - CH - - - FAD binding domain
EFPMHGIB_00748 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EFPMHGIB_00749 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
EFPMHGIB_00750 2.57e-78 yhjD - - - - - - -
EFPMHGIB_00751 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
EFPMHGIB_00752 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFPMHGIB_00753 3.27e-53 yhjA - - S - - - Excalibur calcium-binding domain
EFPMHGIB_00754 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_00755 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EFPMHGIB_00756 9.84e-45 yhzC - - S - - - IDEAL
EFPMHGIB_00757 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_00758 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EFPMHGIB_00759 6.73e-91 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EFPMHGIB_00760 5.52e-154 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EFPMHGIB_00761 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EFPMHGIB_00762 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EFPMHGIB_00763 8.58e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EFPMHGIB_00764 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EFPMHGIB_00765 4.59e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EFPMHGIB_00766 5.66e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EFPMHGIB_00767 1.26e-101 - - - K - - - acetyltransferase
EFPMHGIB_00768 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_00769 9.64e-308 yhfN - - O - - - Peptidase M48
EFPMHGIB_00770 2.78e-85 yhfM - - - - - - -
EFPMHGIB_00771 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EFPMHGIB_00772 1.01e-141 yhfK - - GM - - - NmrA-like family
EFPMHGIB_00773 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EFPMHGIB_00774 2.82e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EFPMHGIB_00775 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFPMHGIB_00776 6.22e-93 - - - S - - - ASCH
EFPMHGIB_00777 2.68e-253 yhfE - - G - - - peptidase M42
EFPMHGIB_00778 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
EFPMHGIB_00779 4.87e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFPMHGIB_00780 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EFPMHGIB_00781 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00782 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EFPMHGIB_00783 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EFPMHGIB_00784 1.06e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EFPMHGIB_00785 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EFPMHGIB_00786 5.35e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EFPMHGIB_00787 2.31e-24 - - - C - - - Rubrerythrin
EFPMHGIB_00788 6.63e-313 yhfA - - C - - - membrane
EFPMHGIB_00789 1.8e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EFPMHGIB_00790 2.04e-161 ecsC - - S - - - EcsC protein family
EFPMHGIB_00791 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EFPMHGIB_00792 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EFPMHGIB_00793 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EFPMHGIB_00794 5.91e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EFPMHGIB_00795 3.66e-103 trpP - - S - - - Tryptophan transporter TrpP
EFPMHGIB_00796 9.66e-30 - - - - - - - -
EFPMHGIB_00797 1.74e-54 yhaH - - S - - - YtxH-like protein
EFPMHGIB_00798 2.01e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EFPMHGIB_00799 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
EFPMHGIB_00800 3.3e-115 yhaK - - S - - - Putative zincin peptidase
EFPMHGIB_00801 5.51e-173 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EFPMHGIB_00802 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
EFPMHGIB_00803 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EFPMHGIB_00804 0.0 yhaN - - L - - - AAA domain
EFPMHGIB_00805 2.71e-300 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EFPMHGIB_00806 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EFPMHGIB_00807 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_00808 2.29e-36 - - - S - - - YhzD-like protein
EFPMHGIB_00809 3.23e-172 yhaR - - I - - - enoyl-CoA hydratase
EFPMHGIB_00811 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EFPMHGIB_00812 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EFPMHGIB_00813 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EFPMHGIB_00814 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EFPMHGIB_00815 1.69e-257 yhaZ - - L - - - DNA alkylation repair enzyme
EFPMHGIB_00816 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
EFPMHGIB_00817 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
EFPMHGIB_00818 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
EFPMHGIB_00819 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
EFPMHGIB_00820 1.32e-48 yheE - - S - - - Family of unknown function (DUF5342)
EFPMHGIB_00821 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EFPMHGIB_00822 2.24e-141 yheG - - GM - - - NAD(P)H-binding
EFPMHGIB_00823 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EFPMHGIB_00824 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EFPMHGIB_00825 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
EFPMHGIB_00826 3.61e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EFPMHGIB_00827 1.5e-195 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EFPMHGIB_00828 1.63e-199 nodB1 - - G - - - deacetylase
EFPMHGIB_00829 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EFPMHGIB_00830 9.73e-239 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EFPMHGIB_00831 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
EFPMHGIB_00832 3.68e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EFPMHGIB_00833 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFPMHGIB_00834 5.44e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EFPMHGIB_00835 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EFPMHGIB_00836 4.01e-281 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EFPMHGIB_00837 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EFPMHGIB_00838 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EFPMHGIB_00839 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EFPMHGIB_00840 3.9e-243 yhdN - - C - - - Aldo keto reductase
EFPMHGIB_00841 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_00842 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
EFPMHGIB_00843 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
EFPMHGIB_00844 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_00845 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_00846 5e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EFPMHGIB_00847 7.15e-316 yhdG - - E ko:K03294 - ko00000 amino acid
EFPMHGIB_00848 5.51e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_00849 3.56e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EFPMHGIB_00850 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00851 9.79e-202 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EFPMHGIB_00852 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EFPMHGIB_00853 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EFPMHGIB_00854 1.51e-306 ygxB - - M - - - Conserved TM helix
EFPMHGIB_00855 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EFPMHGIB_00856 5.77e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EFPMHGIB_00857 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
EFPMHGIB_00858 1.65e-51 yhdB - - S - - - YhdB-like protein
EFPMHGIB_00859 3.84e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EFPMHGIB_00860 5.67e-146 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_00861 6.28e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_00862 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EFPMHGIB_00863 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EFPMHGIB_00864 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EFPMHGIB_00865 1.63e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EFPMHGIB_00866 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EFPMHGIB_00867 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFPMHGIB_00868 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFPMHGIB_00869 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
EFPMHGIB_00870 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
EFPMHGIB_00871 2.47e-88 yhcU - - S - - - Family of unknown function (DUF5365)
EFPMHGIB_00872 6.51e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EFPMHGIB_00873 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EFPMHGIB_00874 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EFPMHGIB_00875 2.29e-144 yhcQ - - M - - - Spore coat protein
EFPMHGIB_00876 6.57e-226 yhcP - - - - - - -
EFPMHGIB_00877 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFPMHGIB_00878 1.96e-71 yhcM - - - - - - -
EFPMHGIB_00879 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFPMHGIB_00880 1.67e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EFPMHGIB_00881 2.23e-194 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EFPMHGIB_00882 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EFPMHGIB_00883 2.32e-210 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFPMHGIB_00884 1.85e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_00885 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_00886 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00887 1.03e-69 - - - - - - - -
EFPMHGIB_00888 3.95e-59 yhcC - - - - - - -
EFPMHGIB_00889 9.84e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
EFPMHGIB_00890 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EFPMHGIB_00891 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EFPMHGIB_00892 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EFPMHGIB_00893 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EFPMHGIB_00894 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EFPMHGIB_00895 2.46e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EFPMHGIB_00896 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EFPMHGIB_00897 2.29e-141 yhbD - - K - - - Protein of unknown function (DUF4004)
EFPMHGIB_00898 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EFPMHGIB_00899 1.32e-223 yhbB - - S - - - Putative amidase domain
EFPMHGIB_00900 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFPMHGIB_00901 6.43e-146 yhzB - - S - - - B3/4 domain
EFPMHGIB_00903 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_00904 7.69e-100 ygaO - - - - - - -
EFPMHGIB_00905 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFPMHGIB_00907 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EFPMHGIB_00908 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EFPMHGIB_00909 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EFPMHGIB_00910 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EFPMHGIB_00911 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EFPMHGIB_00913 0.0 ygaK - - C - - - Berberine and berberine like
EFPMHGIB_00914 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EFPMHGIB_00915 3.18e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EFPMHGIB_00916 1.58e-36 - - - - - - - -
EFPMHGIB_00917 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
EFPMHGIB_00949 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EFPMHGIB_00950 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EFPMHGIB_00951 1.07e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
EFPMHGIB_00952 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
EFPMHGIB_00953 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EFPMHGIB_00954 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EFPMHGIB_00955 2.59e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
EFPMHGIB_00956 1.96e-273 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
EFPMHGIB_00957 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
EFPMHGIB_00959 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
EFPMHGIB_00960 3.15e-230 ytcB - - M - - - NAD-dependent epimerase dehydratase
EFPMHGIB_00961 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFPMHGIB_00962 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
EFPMHGIB_00963 3.53e-168 yteA - - T - - - COG1734 DnaK suppressor protein
EFPMHGIB_00964 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EFPMHGIB_00965 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EFPMHGIB_00966 1.1e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EFPMHGIB_00967 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EFPMHGIB_00968 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EFPMHGIB_00969 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EFPMHGIB_00970 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EFPMHGIB_00971 2.91e-177 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EFPMHGIB_00972 3.03e-295 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EFPMHGIB_00973 2.77e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
EFPMHGIB_00974 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EFPMHGIB_00975 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EFPMHGIB_00976 7.51e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EFPMHGIB_00977 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EFPMHGIB_00978 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EFPMHGIB_00979 3.41e-112 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EFPMHGIB_00980 1.13e-93 ytkA - - S - - - YtkA-like
EFPMHGIB_00982 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EFPMHGIB_00983 3.2e-81 ytkC - - S - - - Bacteriophage holin family
EFPMHGIB_00984 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EFPMHGIB_00985 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EFPMHGIB_00986 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EFPMHGIB_00987 4.41e-239 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EFPMHGIB_00988 2.23e-189 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EFPMHGIB_00989 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
EFPMHGIB_00990 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EFPMHGIB_00991 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFPMHGIB_00992 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EFPMHGIB_00993 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_00994 1.68e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EFPMHGIB_00995 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EFPMHGIB_00996 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EFPMHGIB_00997 1.86e-134 ytqB - - J - - - Putative rRNA methylase
EFPMHGIB_00998 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EFPMHGIB_00999 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
EFPMHGIB_01001 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EFPMHGIB_01002 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_01003 1.72e-192 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EFPMHGIB_01004 5.96e-180 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EFPMHGIB_01005 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_01006 8.41e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EFPMHGIB_01007 1.57e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_01008 2.15e-237 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EFPMHGIB_01009 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_01010 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EFPMHGIB_01011 5.75e-78 yttA - - S - - - Pfam Transposase IS66
EFPMHGIB_01012 1.41e-267 yttB - - EGP - - - Major facilitator superfamily
EFPMHGIB_01013 2.12e-180 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EFPMHGIB_01014 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
EFPMHGIB_01015 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EFPMHGIB_01016 4.98e-68 ytwF - - P - - - Sulfurtransferase
EFPMHGIB_01017 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EFPMHGIB_01018 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EFPMHGIB_01019 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFPMHGIB_01020 7.08e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EFPMHGIB_01021 1.53e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_01022 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
EFPMHGIB_01023 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EFPMHGIB_01024 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EFPMHGIB_01025 2.21e-276 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EFPMHGIB_01026 1.62e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EFPMHGIB_01027 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EFPMHGIB_01028 2.83e-282 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EFPMHGIB_01029 1.28e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
EFPMHGIB_01030 5.08e-192 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EFPMHGIB_01031 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EFPMHGIB_01032 0.0 ytdP - - K - - - Transcriptional regulator
EFPMHGIB_01033 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EFPMHGIB_01034 1.13e-276 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
EFPMHGIB_01035 1.6e-92 yteS - - G - - - transport
EFPMHGIB_01036 1.71e-314 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
EFPMHGIB_01037 1.55e-149 yteU - - S - - - Integral membrane protein
EFPMHGIB_01038 2.14e-36 yteV - - S - - - Sporulation protein Cse60
EFPMHGIB_01039 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EFPMHGIB_01040 4.04e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EFPMHGIB_01041 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_01042 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EFPMHGIB_01043 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EFPMHGIB_01044 3.27e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EFPMHGIB_01045 1.86e-250 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EFPMHGIB_01046 1.65e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EFPMHGIB_01047 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EFPMHGIB_01048 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EFPMHGIB_01049 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EFPMHGIB_01050 4.92e-212 ytlQ - - - - - - -
EFPMHGIB_01051 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EFPMHGIB_01052 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EFPMHGIB_01053 3.02e-192 ytmP - - M - - - Phosphotransferase
EFPMHGIB_01054 9.51e-61 ytzH - - S - - - YtzH-like protein
EFPMHGIB_01055 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EFPMHGIB_01056 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EFPMHGIB_01057 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EFPMHGIB_01058 6.75e-67 ytzB - - S - - - small secreted protein
EFPMHGIB_01059 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EFPMHGIB_01060 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EFPMHGIB_01061 3.17e-75 ytpP - - CO - - - Thioredoxin
EFPMHGIB_01062 2.06e-191 ytpQ - - S - - - Belongs to the UPF0354 family
EFPMHGIB_01063 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFPMHGIB_01064 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EFPMHGIB_01065 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EFPMHGIB_01066 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EFPMHGIB_01067 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EFPMHGIB_01068 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
EFPMHGIB_01069 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EFPMHGIB_01070 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EFPMHGIB_01071 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EFPMHGIB_01072 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EFPMHGIB_01073 3.82e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EFPMHGIB_01074 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EFPMHGIB_01075 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EFPMHGIB_01076 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EFPMHGIB_01077 1.85e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFPMHGIB_01079 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFPMHGIB_01080 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EFPMHGIB_01081 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EFPMHGIB_01082 1.2e-141 yttP - - K - - - Transcriptional regulator
EFPMHGIB_01083 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EFPMHGIB_01084 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFPMHGIB_01085 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EFPMHGIB_01086 1.07e-263 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EFPMHGIB_01087 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFPMHGIB_01088 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
EFPMHGIB_01089 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EFPMHGIB_01090 0.0 ytcJ - - S - - - amidohydrolase
EFPMHGIB_01091 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFPMHGIB_01092 2.79e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EFPMHGIB_01093 4.08e-112 yteJ - - S - - - RDD family
EFPMHGIB_01094 8.34e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
EFPMHGIB_01095 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
EFPMHGIB_01096 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFPMHGIB_01097 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EFPMHGIB_01098 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFPMHGIB_01099 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EFPMHGIB_01100 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EFPMHGIB_01101 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EFPMHGIB_01103 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_01104 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
EFPMHGIB_01105 1.37e-220 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EFPMHGIB_01106 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EFPMHGIB_01107 7.48e-194 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EFPMHGIB_01108 4.49e-191 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EFPMHGIB_01109 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_01110 7.89e-154 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_01111 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EFPMHGIB_01112 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_01113 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EFPMHGIB_01114 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_01115 2.31e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
EFPMHGIB_01116 1.58e-301 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EFPMHGIB_01117 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
EFPMHGIB_01118 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
EFPMHGIB_01119 2.15e-63 ytpI - - S - - - YtpI-like protein
EFPMHGIB_01120 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EFPMHGIB_01121 1.15e-39 - - - - - - - -
EFPMHGIB_01122 5.12e-112 ytrI - - - - - - -
EFPMHGIB_01123 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
EFPMHGIB_01124 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EFPMHGIB_01125 2.01e-285 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EFPMHGIB_01126 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFPMHGIB_01127 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EFPMHGIB_01128 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EFPMHGIB_01129 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EFPMHGIB_01130 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EFPMHGIB_01131 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
EFPMHGIB_01132 4.46e-93 ytwI - - S - - - membrane
EFPMHGIB_01133 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EFPMHGIB_01134 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EFPMHGIB_01135 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EFPMHGIB_01136 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_01137 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EFPMHGIB_01138 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFPMHGIB_01139 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EFPMHGIB_01140 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
EFPMHGIB_01141 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFPMHGIB_01142 4.54e-205 ytbE - - S - - - reductase
EFPMHGIB_01143 2.64e-253 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EFPMHGIB_01144 9.85e-88 ytcD - - K - - - Transcriptional regulator
EFPMHGIB_01145 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFPMHGIB_01146 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EFPMHGIB_01147 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFPMHGIB_01148 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EFPMHGIB_01149 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EFPMHGIB_01150 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
EFPMHGIB_01151 5.98e-206 ytxC - - S - - - YtxC-like family
EFPMHGIB_01152 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFPMHGIB_01153 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EFPMHGIB_01154 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_01155 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EFPMHGIB_01156 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EFPMHGIB_01157 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EFPMHGIB_01159 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFPMHGIB_01160 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EFPMHGIB_01161 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFPMHGIB_01162 1.27e-59 ysdA - - S - - - Membrane
EFPMHGIB_01163 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
EFPMHGIB_01164 2.93e-260 ysdC - - G - - - COG1363 Cellulase M and related proteins
EFPMHGIB_01165 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EFPMHGIB_01166 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EFPMHGIB_01167 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EFPMHGIB_01168 1.99e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EFPMHGIB_01169 6.06e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EFPMHGIB_01170 1.07e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EFPMHGIB_01171 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EFPMHGIB_01172 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EFPMHGIB_01173 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EFPMHGIB_01174 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EFPMHGIB_01175 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EFPMHGIB_01176 1.79e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
EFPMHGIB_01177 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EFPMHGIB_01178 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
EFPMHGIB_01179 2.51e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EFPMHGIB_01180 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EFPMHGIB_01181 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFPMHGIB_01182 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFPMHGIB_01183 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFPMHGIB_01184 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFPMHGIB_01185 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EFPMHGIB_01186 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
EFPMHGIB_01187 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EFPMHGIB_01188 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EFPMHGIB_01189 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
EFPMHGIB_01190 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EFPMHGIB_01191 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_01192 4.25e-174 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EFPMHGIB_01193 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EFPMHGIB_01194 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EFPMHGIB_01196 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EFPMHGIB_01197 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EFPMHGIB_01198 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EFPMHGIB_01199 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EFPMHGIB_01200 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
EFPMHGIB_01201 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EFPMHGIB_01202 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EFPMHGIB_01203 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EFPMHGIB_01204 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EFPMHGIB_01205 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_01206 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_01207 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EFPMHGIB_01208 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EFPMHGIB_01209 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EFPMHGIB_01210 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFPMHGIB_01211 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EFPMHGIB_01213 2.64e-178 ysnF - - S - - - protein conserved in bacteria
EFPMHGIB_01214 1.85e-104 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EFPMHGIB_01216 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EFPMHGIB_01217 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EFPMHGIB_01218 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EFPMHGIB_01219 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EFPMHGIB_01220 4.3e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EFPMHGIB_01221 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFPMHGIB_01222 2.98e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFPMHGIB_01223 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
EFPMHGIB_01224 5.13e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EFPMHGIB_01225 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFPMHGIB_01226 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EFPMHGIB_01227 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EFPMHGIB_01228 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EFPMHGIB_01229 4.77e-116 ysxD - - - - - - -
EFPMHGIB_01230 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EFPMHGIB_01231 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EFPMHGIB_01232 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EFPMHGIB_01233 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EFPMHGIB_01234 3.04e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EFPMHGIB_01235 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EFPMHGIB_01236 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EFPMHGIB_01237 9.73e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EFPMHGIB_01238 1.53e-35 - - - - - - - -
EFPMHGIB_01239 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EFPMHGIB_01240 1.83e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EFPMHGIB_01241 1.81e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EFPMHGIB_01242 3.08e-206 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EFPMHGIB_01243 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EFPMHGIB_01244 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EFPMHGIB_01245 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EFPMHGIB_01246 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EFPMHGIB_01247 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EFPMHGIB_01248 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EFPMHGIB_01249 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EFPMHGIB_01250 5.24e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EFPMHGIB_01251 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EFPMHGIB_01252 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EFPMHGIB_01253 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EFPMHGIB_01254 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EFPMHGIB_01255 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EFPMHGIB_01256 7.94e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFPMHGIB_01257 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EFPMHGIB_01258 4.1e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EFPMHGIB_01259 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EFPMHGIB_01260 1.59e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EFPMHGIB_01261 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EFPMHGIB_01262 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EFPMHGIB_01263 1.08e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EFPMHGIB_01264 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EFPMHGIB_01265 2.08e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFPMHGIB_01266 8.63e-165 yebC - - K - - - transcriptional regulatory protein
EFPMHGIB_01267 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
EFPMHGIB_01268 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
EFPMHGIB_01270 2.32e-152 yrzF - - T - - - serine threonine protein kinase
EFPMHGIB_01271 2.65e-246 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
EFPMHGIB_01272 0.0 csbX - - EGP - - - the major facilitator superfamily
EFPMHGIB_01273 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EFPMHGIB_01274 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EFPMHGIB_01275 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EFPMHGIB_01276 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
EFPMHGIB_01277 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EFPMHGIB_01278 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EFPMHGIB_01279 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EFPMHGIB_01280 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
EFPMHGIB_01281 5.83e-143 yrbG - - S - - - membrane
EFPMHGIB_01282 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_01283 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
EFPMHGIB_01284 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EFPMHGIB_01285 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EFPMHGIB_01286 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EFPMHGIB_01287 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EFPMHGIB_01288 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFPMHGIB_01289 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFPMHGIB_01290 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EFPMHGIB_01291 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EFPMHGIB_01293 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EFPMHGIB_01294 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EFPMHGIB_01295 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EFPMHGIB_01296 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EFPMHGIB_01297 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_01298 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EFPMHGIB_01299 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EFPMHGIB_01300 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
EFPMHGIB_01301 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EFPMHGIB_01302 3.39e-106 yrrD - - S - - - protein conserved in bacteria
EFPMHGIB_01303 8.4e-42 yrzR - - - - - - -
EFPMHGIB_01304 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
EFPMHGIB_01305 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFPMHGIB_01306 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFPMHGIB_01307 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EFPMHGIB_01308 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EFPMHGIB_01309 8.81e-242 yrrI - - S - - - AI-2E family transporter
EFPMHGIB_01310 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFPMHGIB_01311 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
EFPMHGIB_01312 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFPMHGIB_01313 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
EFPMHGIB_01314 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EFPMHGIB_01315 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EFPMHGIB_01316 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EFPMHGIB_01317 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EFPMHGIB_01318 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EFPMHGIB_01319 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFPMHGIB_01320 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EFPMHGIB_01321 5.78e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
EFPMHGIB_01322 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
EFPMHGIB_01323 3.44e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EFPMHGIB_01324 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFPMHGIB_01325 4.96e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EFPMHGIB_01326 2.86e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EFPMHGIB_01327 6.93e-49 yrhC - - S - - - YrhC-like protein
EFPMHGIB_01328 1.73e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
EFPMHGIB_01329 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
EFPMHGIB_01330 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EFPMHGIB_01331 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EFPMHGIB_01333 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EFPMHGIB_01334 6.1e-124 yrhH - - Q - - - methyltransferase
EFPMHGIB_01335 3.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EFPMHGIB_01336 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EFPMHGIB_01337 7.54e-211 - 1.1.1.136, 1.1.1.336 - C ko:K02472,ko:K02474,ko:K13015 ko00520,ko05111,map00520,map05111 ko00000,ko00001,ko01000,ko01005 PFAM UDP-glucose GDP-mannose dehydrogenase
EFPMHGIB_01338 2.31e-148 - 5.1.3.2, 5.1.3.20, 5.1.3.7 - GM ko:K01784,ko:K02473,ko:K03274 ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 NmrA-like family
EFPMHGIB_01339 6.6e-147 - - - S ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
EFPMHGIB_01340 5.35e-80 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EFPMHGIB_01341 2.25e-78 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EFPMHGIB_01342 3.8e-121 - - - Q - - - TIGRFAM amino acid adenylation domain
EFPMHGIB_01343 2.89e-54 - - - I - - - COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EFPMHGIB_01344 6.2e-227 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Aromatic amino acid lyase
EFPMHGIB_01345 3.16e-122 - - - EF - - - ATP-grasp domain
EFPMHGIB_01346 1.25e-105 yodQ 3.5.1.16 - E ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EFPMHGIB_01348 3.5e-12 - - - S - - - cell adhesion involved in biofilm formation
EFPMHGIB_01350 2.11e-26 yrhK - - S - - - YrhK-like protein
EFPMHGIB_01351 0.0 oatA - - I - - - Acyltransferase family
EFPMHGIB_01352 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
EFPMHGIB_01353 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_01354 1.14e-191 yrhO - - K - - - Archaeal transcriptional regulator TrmB
EFPMHGIB_01355 5.63e-137 yrhP - - E - - - LysE type translocator
EFPMHGIB_01356 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_01357 0.0 levR - - K - - - PTS system fructose IIA component
EFPMHGIB_01358 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
EFPMHGIB_01359 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
EFPMHGIB_01360 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
EFPMHGIB_01361 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
EFPMHGIB_01362 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EFPMHGIB_01363 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EFPMHGIB_01364 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EFPMHGIB_01365 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EFPMHGIB_01366 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
EFPMHGIB_01367 6.11e-36 yraE - - - ko:K06440 - ko00000 -
EFPMHGIB_01368 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EFPMHGIB_01369 9.61e-84 yraF - - M - - - Spore coat protein
EFPMHGIB_01370 4.19e-50 yraG - - - ko:K06440 - ko00000 -
EFPMHGIB_01371 6.62e-87 - - - E - - - Glyoxalase-like domain
EFPMHGIB_01372 2.92e-81 - - - T - - - sh3 domain protein
EFPMHGIB_01373 6.61e-80 - - - T - - - sh3 domain protein
EFPMHGIB_01374 2.33e-194 - - - S - - - Alpha beta hydrolase
EFPMHGIB_01375 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_01376 9.5e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EFPMHGIB_01377 1.15e-260 yraM - - S - - - PrpF protein
EFPMHGIB_01378 2.97e-210 yraN - - K - - - Transcriptional regulator
EFPMHGIB_01379 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EFPMHGIB_01380 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
EFPMHGIB_01381 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_01382 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
EFPMHGIB_01383 4.65e-63 - - - S - - - YjbR
EFPMHGIB_01384 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
EFPMHGIB_01385 3.1e-126 - - - S - - - Flavin reductase like domain
EFPMHGIB_01386 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
EFPMHGIB_01387 1.02e-192 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
EFPMHGIB_01388 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_01389 4.11e-268 - - - P - - - Major Facilitator Superfamily
EFPMHGIB_01391 6.71e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EFPMHGIB_01392 5.4e-161 yrpD - - S - - - Domain of unknown function, YrpD
EFPMHGIB_01393 2.01e-101 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EFPMHGIB_01394 7.02e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EFPMHGIB_01395 1.21e-211 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EFPMHGIB_01396 1.42e-118 yrdA - - S - - - DinB family
EFPMHGIB_01397 4.27e-132 yrdC - - Q - - - Isochorismatase family
EFPMHGIB_01398 5.86e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EFPMHGIB_01399 1.76e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EFPMHGIB_01400 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
EFPMHGIB_01401 9.34e-176 azlC - - E - - - AzlC protein
EFPMHGIB_01402 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
EFPMHGIB_01403 1.01e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EFPMHGIB_01404 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
EFPMHGIB_01405 6.6e-201 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EFPMHGIB_01406 1.75e-87 yodA - - S - - - tautomerase
EFPMHGIB_01407 2e-211 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EFPMHGIB_01408 7.41e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
EFPMHGIB_01409 1.64e-202 - - - K - - - Transcriptional regulator
EFPMHGIB_01410 2.84e-215 yrdR - - EG - - - EamA-like transporter family
EFPMHGIB_01411 2.45e-23 - - - S - - - YrzO-like protein
EFPMHGIB_01412 6.89e-296 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EFPMHGIB_01413 1.07e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EFPMHGIB_01414 3.09e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_01415 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
EFPMHGIB_01416 1.23e-135 yrkC - - G - - - Cupin domain
EFPMHGIB_01417 4.38e-52 yrkD - - S - - - protein conserved in bacteria
EFPMHGIB_01418 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
EFPMHGIB_01419 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
EFPMHGIB_01420 1.36e-268 yrkH - - P - - - Rhodanese Homology Domain
EFPMHGIB_01421 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
EFPMHGIB_01422 2.36e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
EFPMHGIB_01423 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
EFPMHGIB_01424 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
EFPMHGIB_01425 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
EFPMHGIB_01426 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EFPMHGIB_01427 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
EFPMHGIB_01428 7.32e-306 yrkQ - - T - - - Histidine kinase
EFPMHGIB_01429 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
EFPMHGIB_01430 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_01431 1.58e-122 xkdA - - E - - - IrrE N-terminal-like domain
EFPMHGIB_01432 8.73e-132 yqaC - - F - - - adenylate kinase activity
EFPMHGIB_01434 1.25e-74 - - - K - - - sequence-specific DNA binding
EFPMHGIB_01435 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
EFPMHGIB_01437 1.04e-133 - - - - - - - -
EFPMHGIB_01441 3.18e-213 yqaJ - - L - - - YqaJ-like viral recombinase domain
EFPMHGIB_01442 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
EFPMHGIB_01443 5.29e-156 yqaL - - L - - - DnaD domain protein
EFPMHGIB_01444 5.04e-207 yqaM - - L - - - IstB-like ATP binding protein
EFPMHGIB_01446 1.28e-93 rusA - - L - - - Endodeoxyribonuclease RusA
EFPMHGIB_01447 8.38e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
EFPMHGIB_01449 2.83e-99 yqaQ - - L - - - Transposase
EFPMHGIB_01451 7.73e-147 yqaS - - L - - - DNA packaging
EFPMHGIB_01452 2.69e-312 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
EFPMHGIB_01453 0.0 yqbA - - S - - - portal protein
EFPMHGIB_01454 1.79e-194 - - - S - - - Phage Mu protein F like protein
EFPMHGIB_01456 4.23e-158 yqbD - - L - - - Putative phage serine protease XkdF
EFPMHGIB_01457 8.83e-214 xkdG - - S - - - Phage capsid family
EFPMHGIB_01458 2.12e-60 - - - S - - - YqbF, hypothetical protein domain
EFPMHGIB_01459 1.43e-87 - - - S - - - Protein of unknown function (DUF3199)
EFPMHGIB_01460 9.68e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
EFPMHGIB_01461 1.79e-112 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EFPMHGIB_01462 1.48e-98 yqbJ - - - - - - -
EFPMHGIB_01463 1.21e-34 - - - - - - - -
EFPMHGIB_01464 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
EFPMHGIB_01465 7.03e-98 xkdM - - S - - - Phage tail tube protein
EFPMHGIB_01467 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EFPMHGIB_01468 0.0 xkdO - - L - - - Transglycosylase SLT domain
EFPMHGIB_01469 6.56e-156 xkdP - - S - - - Lysin motif
EFPMHGIB_01470 1.02e-231 xkdQ - - G - - - NLP P60 protein
EFPMHGIB_01471 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
EFPMHGIB_01472 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
EFPMHGIB_01473 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EFPMHGIB_01474 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EFPMHGIB_01475 3e-54 - - - - - - - -
EFPMHGIB_01476 2.91e-283 - - - - - - - -
EFPMHGIB_01477 1.01e-73 xkdW - - S - - - XkdW protein
EFPMHGIB_01478 9.34e-33 - - - - - - - -
EFPMHGIB_01479 2.45e-213 xepA - - - - - - -
EFPMHGIB_01480 8.36e-89 - - - S - - - Bacteriophage holin family
EFPMHGIB_01481 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EFPMHGIB_01483 5.4e-80 - - - - - - - -
EFPMHGIB_01485 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
EFPMHGIB_01486 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
EFPMHGIB_01489 1.74e-119 - - - S - - - Tetratricopeptide repeat
EFPMHGIB_01490 4.35e-53 - - - S - - - Spore coat protein Z
EFPMHGIB_01491 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
EFPMHGIB_01492 1.55e-61 - - - - - - - -
EFPMHGIB_01493 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
EFPMHGIB_01494 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
EFPMHGIB_01495 1.69e-142 - - - S - - - PepSY-associated TM region
EFPMHGIB_01496 9e-62 - - - S - - - PepSY-associated TM region
EFPMHGIB_01497 1.37e-30 - - - S - - - YtkA-like
EFPMHGIB_01498 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EFPMHGIB_01499 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
EFPMHGIB_01500 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_01501 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
EFPMHGIB_01502 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
EFPMHGIB_01503 0.0 - - - L ko:K06400 - ko00000 Recombinase
EFPMHGIB_01504 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_01505 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
EFPMHGIB_01506 9.38e-171 - - - - - - - -
EFPMHGIB_01507 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
EFPMHGIB_01508 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
EFPMHGIB_01509 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
EFPMHGIB_01510 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EFPMHGIB_01511 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EFPMHGIB_01513 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EFPMHGIB_01514 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EFPMHGIB_01515 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EFPMHGIB_01516 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EFPMHGIB_01517 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFPMHGIB_01518 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EFPMHGIB_01519 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EFPMHGIB_01520 9.8e-179 yqeM - - Q - - - Methyltransferase
EFPMHGIB_01521 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFPMHGIB_01522 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EFPMHGIB_01523 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EFPMHGIB_01524 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EFPMHGIB_01525 2.36e-22 - - - S - - - YqzM-like protein
EFPMHGIB_01526 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EFPMHGIB_01527 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EFPMHGIB_01528 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EFPMHGIB_01529 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EFPMHGIB_01530 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
EFPMHGIB_01531 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EFPMHGIB_01532 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EFPMHGIB_01533 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EFPMHGIB_01534 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFPMHGIB_01535 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EFPMHGIB_01536 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EFPMHGIB_01537 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EFPMHGIB_01538 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EFPMHGIB_01539 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EFPMHGIB_01540 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EFPMHGIB_01541 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EFPMHGIB_01542 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EFPMHGIB_01543 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EFPMHGIB_01544 8.78e-192 yqfA - - S - - - UPF0365 protein
EFPMHGIB_01545 3.13e-79 yqfB - - - - - - -
EFPMHGIB_01546 2.07e-60 yqfC - - S - - - sporulation protein YqfC
EFPMHGIB_01547 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EFPMHGIB_01548 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EFPMHGIB_01550 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EFPMHGIB_01551 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFPMHGIB_01552 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EFPMHGIB_01553 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EFPMHGIB_01554 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFPMHGIB_01555 5.29e-27 - - - S - - - YqzL-like protein
EFPMHGIB_01556 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EFPMHGIB_01557 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EFPMHGIB_01558 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EFPMHGIB_01559 3.29e-144 ccpN - - K - - - CBS domain
EFPMHGIB_01560 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EFPMHGIB_01561 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EFPMHGIB_01562 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EFPMHGIB_01563 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EFPMHGIB_01564 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EFPMHGIB_01565 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EFPMHGIB_01566 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFPMHGIB_01567 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EFPMHGIB_01568 4.45e-45 yqfQ - - S - - - YqfQ-like protein
EFPMHGIB_01569 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EFPMHGIB_01570 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EFPMHGIB_01571 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EFPMHGIB_01572 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EFPMHGIB_01573 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EFPMHGIB_01574 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EFPMHGIB_01575 2.04e-81 yqfX - - S - - - membrane
EFPMHGIB_01576 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EFPMHGIB_01577 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
EFPMHGIB_01578 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
EFPMHGIB_01579 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EFPMHGIB_01580 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EFPMHGIB_01581 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EFPMHGIB_01582 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EFPMHGIB_01583 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EFPMHGIB_01584 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EFPMHGIB_01585 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EFPMHGIB_01586 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFPMHGIB_01587 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFPMHGIB_01588 1.09e-93 yqzC - - S - - - YceG-like family
EFPMHGIB_01589 2.81e-67 yqzD - - - - - - -
EFPMHGIB_01591 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
EFPMHGIB_01592 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EFPMHGIB_01593 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFPMHGIB_01594 3.38e-14 yqgO - - - - - - -
EFPMHGIB_01595 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
EFPMHGIB_01596 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
EFPMHGIB_01597 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EFPMHGIB_01598 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EFPMHGIB_01599 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EFPMHGIB_01600 2.69e-256 yqgU - - - - - - -
EFPMHGIB_01601 7.34e-66 yqgV - - S - - - Thiamine-binding protein
EFPMHGIB_01602 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
EFPMHGIB_01603 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EFPMHGIB_01604 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EFPMHGIB_01605 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EFPMHGIB_01607 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFPMHGIB_01608 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EFPMHGIB_01609 1.51e-233 yqxL - - P - - - Mg2 transporter protein
EFPMHGIB_01610 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
EFPMHGIB_01612 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFPMHGIB_01613 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EFPMHGIB_01614 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EFPMHGIB_01615 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
EFPMHGIB_01616 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EFPMHGIB_01617 2.77e-44 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EFPMHGIB_01618 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EFPMHGIB_01619 3.33e-35 yqzE - - S - - - YqzE-like protein
EFPMHGIB_01620 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
EFPMHGIB_01621 8e-156 yqxM - - - ko:K19433 - ko00000 -
EFPMHGIB_01622 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EFPMHGIB_01623 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EFPMHGIB_01624 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EFPMHGIB_01625 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EFPMHGIB_01626 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
EFPMHGIB_01627 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EFPMHGIB_01628 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EFPMHGIB_01629 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EFPMHGIB_01630 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EFPMHGIB_01631 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EFPMHGIB_01632 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EFPMHGIB_01633 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EFPMHGIB_01634 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EFPMHGIB_01635 5.18e-81 yqhP - - - - - - -
EFPMHGIB_01636 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
EFPMHGIB_01637 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
EFPMHGIB_01638 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
EFPMHGIB_01639 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EFPMHGIB_01640 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFPMHGIB_01641 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
EFPMHGIB_01642 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EFPMHGIB_01643 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EFPMHGIB_01644 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EFPMHGIB_01645 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EFPMHGIB_01646 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EFPMHGIB_01647 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EFPMHGIB_01648 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EFPMHGIB_01649 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EFPMHGIB_01650 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFPMHGIB_01651 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EFPMHGIB_01652 1.65e-88 yqhY - - S - - - protein conserved in bacteria
EFPMHGIB_01653 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFPMHGIB_01654 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFPMHGIB_01655 2.05e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFPMHGIB_01656 3.81e-50 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFPMHGIB_01657 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EFPMHGIB_01658 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EFPMHGIB_01659 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EFPMHGIB_01660 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EFPMHGIB_01661 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EFPMHGIB_01662 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EFPMHGIB_01663 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EFPMHGIB_01665 3.43e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EFPMHGIB_01666 4.74e-37 - - - - - - - -
EFPMHGIB_01667 2.7e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EFPMHGIB_01668 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EFPMHGIB_01669 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EFPMHGIB_01670 2.41e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EFPMHGIB_01671 1.93e-265 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EFPMHGIB_01672 1.12e-265 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EFPMHGIB_01673 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EFPMHGIB_01674 4.18e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EFPMHGIB_01675 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EFPMHGIB_01676 0.0 bkdR - - KT - - - Transcriptional regulator
EFPMHGIB_01677 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EFPMHGIB_01678 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EFPMHGIB_01679 3.96e-254 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EFPMHGIB_01680 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFPMHGIB_01681 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFPMHGIB_01682 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFPMHGIB_01683 2.18e-287 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFPMHGIB_01684 7.45e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
EFPMHGIB_01685 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_01686 1.21e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFPMHGIB_01687 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
EFPMHGIB_01688 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EFPMHGIB_01689 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EFPMHGIB_01690 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EFPMHGIB_01691 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EFPMHGIB_01692 2.41e-128 yqjB - - S - - - protein conserved in bacteria
EFPMHGIB_01694 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EFPMHGIB_01695 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EFPMHGIB_01696 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EFPMHGIB_01697 1.36e-69 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
EFPMHGIB_01698 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFPMHGIB_01699 1.77e-32 yqzJ - - - - - - -
EFPMHGIB_01700 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFPMHGIB_01701 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFPMHGIB_01702 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EFPMHGIB_01703 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EFPMHGIB_01704 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EFPMHGIB_01705 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFPMHGIB_01706 1.72e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EFPMHGIB_01707 0.0 rocB - - E - - - arginine degradation protein
EFPMHGIB_01708 3.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFPMHGIB_01709 3.27e-229 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EFPMHGIB_01710 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_01711 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EFPMHGIB_01712 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EFPMHGIB_01713 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_01715 6.83e-288 yqjV - - G - - - Major Facilitator Superfamily
EFPMHGIB_01717 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFPMHGIB_01718 1.87e-65 yqiX - - S - - - YolD-like protein
EFPMHGIB_01719 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EFPMHGIB_01720 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EFPMHGIB_01721 2.89e-251 yqkA - - K - - - GrpB protein
EFPMHGIB_01722 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
EFPMHGIB_01723 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
EFPMHGIB_01724 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EFPMHGIB_01725 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
EFPMHGIB_01726 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EFPMHGIB_01727 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
EFPMHGIB_01728 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EFPMHGIB_01729 2.62e-283 yqxK - - L - - - DNA helicase
EFPMHGIB_01730 3.18e-77 ansR - - K - - - Transcriptional regulator
EFPMHGIB_01731 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EFPMHGIB_01732 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EFPMHGIB_01733 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EFPMHGIB_01734 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EFPMHGIB_01735 3.73e-44 yqkK - - - - - - -
EFPMHGIB_01736 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EFPMHGIB_01737 2.64e-103 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EFPMHGIB_01738 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
EFPMHGIB_01739 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EFPMHGIB_01740 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EFPMHGIB_01741 5.66e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EFPMHGIB_01742 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EFPMHGIB_01743 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EFPMHGIB_01744 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EFPMHGIB_01745 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_01746 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EFPMHGIB_01747 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
EFPMHGIB_01748 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EFPMHGIB_01749 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EFPMHGIB_01750 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EFPMHGIB_01751 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
EFPMHGIB_01752 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EFPMHGIB_01753 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EFPMHGIB_01754 3.12e-192 ypuA - - S - - - Secreted protein
EFPMHGIB_01755 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFPMHGIB_01757 1.61e-16 - - - S - - - SNARE associated Golgi protein
EFPMHGIB_01758 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
EFPMHGIB_01759 4.99e-127 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EFPMHGIB_01760 5.98e-72 ypuD - - - - - - -
EFPMHGIB_01761 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EFPMHGIB_01762 2.05e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EFPMHGIB_01763 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EFPMHGIB_01764 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EFPMHGIB_01765 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_01766 3.43e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EFPMHGIB_01767 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFPMHGIB_01768 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFPMHGIB_01769 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
EFPMHGIB_01770 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EFPMHGIB_01771 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EFPMHGIB_01772 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EFPMHGIB_01773 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EFPMHGIB_01774 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EFPMHGIB_01775 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EFPMHGIB_01776 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EFPMHGIB_01777 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_01778 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_01779 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_01780 1.49e-254 rsiX - - - - - - -
EFPMHGIB_01781 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EFPMHGIB_01782 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFPMHGIB_01783 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFPMHGIB_01784 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EFPMHGIB_01785 6.62e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EFPMHGIB_01786 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EFPMHGIB_01787 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EFPMHGIB_01788 8.27e-143 ypbE - - M - - - Lysin motif
EFPMHGIB_01789 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
EFPMHGIB_01790 6.15e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EFPMHGIB_01791 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EFPMHGIB_01792 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EFPMHGIB_01793 6.04e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EFPMHGIB_01794 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EFPMHGIB_01795 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EFPMHGIB_01796 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
EFPMHGIB_01797 2.2e-142 ypfA - - M - - - Flagellar protein YcgR
EFPMHGIB_01798 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
EFPMHGIB_01799 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EFPMHGIB_01800 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EFPMHGIB_01801 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EFPMHGIB_01802 1.13e-11 - - - S - - - YpzI-like protein
EFPMHGIB_01803 1.11e-133 yphA - - - - - - -
EFPMHGIB_01804 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
EFPMHGIB_01805 1.45e-38 ypzH - - - - - - -
EFPMHGIB_01806 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EFPMHGIB_01807 2.2e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EFPMHGIB_01808 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
EFPMHGIB_01809 1.5e-176 yphF - - - - - - -
EFPMHGIB_01810 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EFPMHGIB_01811 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFPMHGIB_01812 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EFPMHGIB_01813 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EFPMHGIB_01814 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EFPMHGIB_01815 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EFPMHGIB_01816 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EFPMHGIB_01817 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EFPMHGIB_01818 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EFPMHGIB_01819 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFPMHGIB_01820 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EFPMHGIB_01821 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EFPMHGIB_01822 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFPMHGIB_01823 2.48e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EFPMHGIB_01824 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EFPMHGIB_01825 3.3e-152 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EFPMHGIB_01826 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EFPMHGIB_01827 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EFPMHGIB_01828 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFPMHGIB_01829 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EFPMHGIB_01830 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EFPMHGIB_01831 2.5e-297 ypiA - - S - - - COG0457 FOG TPR repeat
EFPMHGIB_01832 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
EFPMHGIB_01833 1.08e-97 ypiF - - S - - - Protein of unknown function (DUF2487)
EFPMHGIB_01834 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EFPMHGIB_01835 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EFPMHGIB_01836 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EFPMHGIB_01837 4e-126 ypjA - - S - - - membrane
EFPMHGIB_01838 2.79e-182 ypjB - - S - - - sporulation protein
EFPMHGIB_01839 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EFPMHGIB_01840 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EFPMHGIB_01841 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EFPMHGIB_01842 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EFPMHGIB_01843 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EFPMHGIB_01844 1.16e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EFPMHGIB_01845 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFPMHGIB_01846 5.68e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFPMHGIB_01847 5.66e-193 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EFPMHGIB_01848 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EFPMHGIB_01849 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EFPMHGIB_01850 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EFPMHGIB_01851 3.6e-31 ypmA - - S - - - Protein of unknown function (DUF4264)
EFPMHGIB_01852 2.66e-102 ypmB - - S - - - protein conserved in bacteria
EFPMHGIB_01853 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EFPMHGIB_01854 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EFPMHGIB_01855 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EFPMHGIB_01856 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFPMHGIB_01857 1.43e-121 ypoC - - - - - - -
EFPMHGIB_01858 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EFPMHGIB_01859 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFPMHGIB_01860 4.36e-239 yppC - - S - - - Protein of unknown function (DUF2515)
EFPMHGIB_01863 3.11e-09 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
EFPMHGIB_01864 9.21e-11 - - - S - - - YppF-like protein
EFPMHGIB_01865 8.72e-68 yppG - - S - - - YppG-like protein
EFPMHGIB_01866 1.45e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EFPMHGIB_01867 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EFPMHGIB_01868 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EFPMHGIB_01869 1.39e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EFPMHGIB_01870 1.19e-128 ypsA - - S - - - Belongs to the UPF0398 family
EFPMHGIB_01871 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EFPMHGIB_01872 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EFPMHGIB_01874 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EFPMHGIB_01875 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_01876 1.41e-201 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EFPMHGIB_01877 1.19e-234 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
EFPMHGIB_01878 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
EFPMHGIB_01879 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
EFPMHGIB_01880 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
EFPMHGIB_01881 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EFPMHGIB_01882 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EFPMHGIB_01883 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EFPMHGIB_01884 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EFPMHGIB_01885 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EFPMHGIB_01886 0.0 ypbR - - S - - - Dynamin family
EFPMHGIB_01887 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
EFPMHGIB_01888 1.08e-11 - - - - - - - -
EFPMHGIB_01889 2.26e-213 ypcP - - L - - - 5'3' exonuclease
EFPMHGIB_01890 5.23e-05 - - - - ko:K06429 - ko00000 -
EFPMHGIB_01891 6.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EFPMHGIB_01892 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EFPMHGIB_01893 1.9e-161 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EFPMHGIB_01894 1.54e-37 ypeQ - - S - - - Zinc-finger
EFPMHGIB_01895 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
EFPMHGIB_01896 1.17e-22 degR - - - - - - -
EFPMHGIB_01897 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EFPMHGIB_01898 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EFPMHGIB_01899 1.49e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EFPMHGIB_01900 7.69e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EFPMHGIB_01901 2.6e-135 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EFPMHGIB_01902 2.83e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EFPMHGIB_01903 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EFPMHGIB_01904 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
EFPMHGIB_01905 1.14e-182 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EFPMHGIB_01906 1.16e-146 ypjP - - S - - - YpjP-like protein
EFPMHGIB_01907 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EFPMHGIB_01908 4.04e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFPMHGIB_01909 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFPMHGIB_01910 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EFPMHGIB_01911 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EFPMHGIB_01912 1.4e-236 yplP - - K - - - Transcriptional regulator
EFPMHGIB_01913 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EFPMHGIB_01914 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EFPMHGIB_01915 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EFPMHGIB_01916 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EFPMHGIB_01917 6.8e-129 ypmS - - S - - - protein conserved in bacteria
EFPMHGIB_01918 2.13e-40 ypmT - - S - - - Uncharacterized ympT
EFPMHGIB_01919 9.99e-290 mepA - - V - - - MATE efflux family protein
EFPMHGIB_01920 4.14e-94 ypoP - - K - - - transcriptional
EFPMHGIB_01921 1.4e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFPMHGIB_01922 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EFPMHGIB_01923 4.75e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EFPMHGIB_01924 1.1e-277 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EFPMHGIB_01925 5.2e-225 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EFPMHGIB_01926 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
EFPMHGIB_01927 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
EFPMHGIB_01928 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EFPMHGIB_01929 1.39e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EFPMHGIB_01931 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFPMHGIB_01933 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EFPMHGIB_01934 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EFPMHGIB_01935 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EFPMHGIB_01936 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EFPMHGIB_01937 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
EFPMHGIB_01938 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
EFPMHGIB_01939 1.29e-159 yodN - - - - - - -
EFPMHGIB_01941 5.18e-34 yozD - - S - - - YozD-like protein
EFPMHGIB_01942 2.33e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EFPMHGIB_01943 1.17e-71 yodL - - S - - - YodL-like
EFPMHGIB_01944 2.08e-12 - - - - - - - -
EFPMHGIB_01945 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EFPMHGIB_01946 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EFPMHGIB_01947 2.93e-42 yodI - - - - - - -
EFPMHGIB_01948 3.69e-167 yodH - - Q - - - Methyltransferase
EFPMHGIB_01949 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EFPMHGIB_01950 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFPMHGIB_01951 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
EFPMHGIB_01952 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EFPMHGIB_01953 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EFPMHGIB_01954 1.11e-139 yodC - - C - - - nitroreductase
EFPMHGIB_01955 2.63e-73 yodB - - K - - - transcriptional
EFPMHGIB_01956 3.97e-84 iolK - - S - - - tautomerase
EFPMHGIB_01957 1.6e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EFPMHGIB_01958 5.59e-14 - - - - - - - -
EFPMHGIB_01959 7.69e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EFPMHGIB_01960 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EFPMHGIB_01961 1.07e-57 - - - - - - - -
EFPMHGIB_01962 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EFPMHGIB_01963 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EFPMHGIB_01964 7.92e-66 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFPMHGIB_01965 2.7e-115 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFPMHGIB_01966 8.38e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EFPMHGIB_01968 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFPMHGIB_01969 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EFPMHGIB_01970 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EFPMHGIB_01971 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EFPMHGIB_01972 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EFPMHGIB_01973 0.0 yojO - - P - - - Von Willebrand factor
EFPMHGIB_01974 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EFPMHGIB_01975 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EFPMHGIB_01976 7.79e-213 yocS - - S ko:K03453 - ko00000 -transporter
EFPMHGIB_01977 7.21e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EFPMHGIB_01978 6.49e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EFPMHGIB_01979 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EFPMHGIB_01980 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EFPMHGIB_01981 1.91e-42 yozC - - - - - - -
EFPMHGIB_01982 2.17e-74 yozO - - S - - - Bacterial PH domain
EFPMHGIB_01983 1.83e-49 yocN - - - - - - -
EFPMHGIB_01984 2.94e-55 yozN - - - - - - -
EFPMHGIB_01985 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EFPMHGIB_01986 5.79e-43 - - - - - - - -
EFPMHGIB_01987 3.02e-70 yocL - - - - - - -
EFPMHGIB_01988 1.42e-107 yocK - - T - - - general stress protein
EFPMHGIB_01989 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EFPMHGIB_01990 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EFPMHGIB_01991 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
EFPMHGIB_01992 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_01993 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_01994 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EFPMHGIB_01995 3.19e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EFPMHGIB_01996 1.08e-121 yocC - - - - - - -
EFPMHGIB_01997 2.6e-185 - - - - - - - -
EFPMHGIB_01998 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
EFPMHGIB_01999 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFPMHGIB_02000 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EFPMHGIB_02001 4.1e-118 yobW - - - - - - -
EFPMHGIB_02002 3.81e-225 yobV - - K - - - WYL domain
EFPMHGIB_02003 1.01e-110 - - - K - - - Bacterial transcription activator, effector binding domain
EFPMHGIB_02004 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EFPMHGIB_02005 3.09e-127 yobS - - K - - - Transcriptional regulator
EFPMHGIB_02006 2.93e-180 - - - J - - - FR47-like protein
EFPMHGIB_02007 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EFPMHGIB_02008 5.86e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EFPMHGIB_02009 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
EFPMHGIB_02010 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
EFPMHGIB_02011 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EFPMHGIB_02012 5.21e-26 - - - - - - - -
EFPMHGIB_02014 1.43e-64 - - - - - - - -
EFPMHGIB_02016 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFPMHGIB_02017 4.52e-201 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFPMHGIB_02019 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EFPMHGIB_02027 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
EFPMHGIB_02028 6.81e-66 - - - S - - - Tetratricopeptide repeat
EFPMHGIB_02032 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EFPMHGIB_02037 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
EFPMHGIB_02040 7.63e-74 - - - K - - - Helix-turn-helix
EFPMHGIB_02041 1e-47 - - - S - - - TM2 domain
EFPMHGIB_02042 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EFPMHGIB_02043 1.36e-108 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EFPMHGIB_02044 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EFPMHGIB_02047 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EFPMHGIB_02048 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
EFPMHGIB_02049 1.89e-100 yoaW - - - - - - -
EFPMHGIB_02050 3.7e-201 yoaV - - EG - - - EamA-like transporter family
EFPMHGIB_02051 1.11e-201 yoaU - - K - - - LysR substrate binding domain
EFPMHGIB_02052 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
EFPMHGIB_02053 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02054 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
EFPMHGIB_02055 1.04e-217 yoaR - - V - - - vancomycin resistance protein
EFPMHGIB_02056 1.87e-113 - - - - - - - -
EFPMHGIB_02058 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
EFPMHGIB_02059 3.86e-183 yoaP - - K - - - YoaP-like
EFPMHGIB_02061 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EFPMHGIB_02064 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
EFPMHGIB_02065 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
EFPMHGIB_02066 1.79e-145 yoaK - - S - - - Membrane
EFPMHGIB_02067 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
EFPMHGIB_02068 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EFPMHGIB_02069 6.22e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
EFPMHGIB_02070 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
EFPMHGIB_02071 1.46e-19 - - - - - - - -
EFPMHGIB_02074 7.24e-45 yoaF - - - - - - -
EFPMHGIB_02075 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFPMHGIB_02076 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFPMHGIB_02077 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EFPMHGIB_02078 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
EFPMHGIB_02079 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
EFPMHGIB_02080 2.41e-300 - - - S - - - Arylsulfotransferase (ASST)
EFPMHGIB_02081 2.39e-115 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFPMHGIB_02082 3.93e-177 yoxB - - - - - - -
EFPMHGIB_02083 1.34e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
EFPMHGIB_02084 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02085 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EFPMHGIB_02086 1.58e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFPMHGIB_02087 3.86e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFPMHGIB_02088 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02089 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EFPMHGIB_02090 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EFPMHGIB_02091 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EFPMHGIB_02092 3.57e-200 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02093 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EFPMHGIB_02094 4.71e-47 yoeD - - G - - - Helix-turn-helix domain
EFPMHGIB_02095 1.14e-124 - - - L - - - Integrase
EFPMHGIB_02097 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EFPMHGIB_02098 3.99e-312 yoeA - - V - - - MATE efflux family protein
EFPMHGIB_02099 1.47e-244 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EFPMHGIB_02100 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EFPMHGIB_02102 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EFPMHGIB_02103 1.2e-122 - - - M - - - FR47-like protein
EFPMHGIB_02104 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EFPMHGIB_02105 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EFPMHGIB_02106 1.95e-109 yuaE - - S - - - DinB superfamily
EFPMHGIB_02107 8.58e-139 yuaD - - - - - - -
EFPMHGIB_02108 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EFPMHGIB_02109 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EFPMHGIB_02110 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EFPMHGIB_02111 5.83e-118 yuaB - - - - - - -
EFPMHGIB_02112 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EFPMHGIB_02113 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
EFPMHGIB_02114 3.31e-52 yubF - - S - - - yiaA/B two helix domain
EFPMHGIB_02115 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFPMHGIB_02116 0.0 yubD - - P - - - Major Facilitator Superfamily
EFPMHGIB_02117 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
EFPMHGIB_02119 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EFPMHGIB_02120 7.34e-254 yubA - - S - - - transporter activity
EFPMHGIB_02121 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EFPMHGIB_02122 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
EFPMHGIB_02123 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
EFPMHGIB_02124 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
EFPMHGIB_02125 9.59e-171 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EFPMHGIB_02126 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
EFPMHGIB_02127 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_02128 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_02129 4.88e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_02130 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_02131 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EFPMHGIB_02132 5.85e-47 - - - - - - - -
EFPMHGIB_02133 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
EFPMHGIB_02134 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EFPMHGIB_02135 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EFPMHGIB_02136 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EFPMHGIB_02137 2.24e-50 - - - - - - - -
EFPMHGIB_02138 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
EFPMHGIB_02139 2.92e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EFPMHGIB_02140 3.48e-94 yugN - - S - - - YugN-like family
EFPMHGIB_02142 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EFPMHGIB_02143 1.59e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EFPMHGIB_02144 1.11e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EFPMHGIB_02145 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EFPMHGIB_02146 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EFPMHGIB_02147 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EFPMHGIB_02148 6.74e-112 alaR - - K - - - Transcriptional regulator
EFPMHGIB_02149 4.03e-200 yugF - - I - - - Hydrolase
EFPMHGIB_02150 6.22e-52 yugE - - S - - - Domain of unknown function (DUF1871)
EFPMHGIB_02151 1.58e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EFPMHGIB_02152 2.14e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02153 5.89e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EFPMHGIB_02154 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EFPMHGIB_02156 6.27e-242 yuxJ - - EGP - - - Major facilitator superfamily
EFPMHGIB_02157 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EFPMHGIB_02158 1.92e-97 yuxK - - S - - - protein conserved in bacteria
EFPMHGIB_02159 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
EFPMHGIB_02160 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EFPMHGIB_02161 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EFPMHGIB_02162 1.84e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EFPMHGIB_02163 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02164 5.25e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EFPMHGIB_02165 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EFPMHGIB_02166 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
EFPMHGIB_02167 1.42e-21 - - - - - - - -
EFPMHGIB_02168 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EFPMHGIB_02169 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFPMHGIB_02170 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFPMHGIB_02171 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFPMHGIB_02172 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFPMHGIB_02173 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EFPMHGIB_02174 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EFPMHGIB_02175 1.35e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EFPMHGIB_02176 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_02177 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02179 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
EFPMHGIB_02180 6.29e-10 - - - S - - - DegQ (SacQ) family
EFPMHGIB_02182 8.73e-09 yuzC - - - - - - -
EFPMHGIB_02183 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EFPMHGIB_02184 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFPMHGIB_02185 1.33e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EFPMHGIB_02186 2.19e-87 - - - S - - - Protein of unknown function (DUF1694)
EFPMHGIB_02187 1.34e-51 yueH - - S - - - YueH-like protein
EFPMHGIB_02188 7.15e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EFPMHGIB_02189 1.98e-68 yueF - - S - - - transporter activity
EFPMHGIB_02190 8.89e-142 yueF - - S - - - transporter activity
EFPMHGIB_02191 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
EFPMHGIB_02192 3.42e-32 - - - S - - - Protein of unknown function (DUF2642)
EFPMHGIB_02193 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EFPMHGIB_02194 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_02195 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
EFPMHGIB_02196 0.0 yueB - - S - - - type VII secretion protein EsaA
EFPMHGIB_02197 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EFPMHGIB_02198 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EFPMHGIB_02199 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EFPMHGIB_02200 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
EFPMHGIB_02201 8.49e-292 yukF - - QT - - - Transcriptional regulator
EFPMHGIB_02202 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EFPMHGIB_02203 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EFPMHGIB_02204 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EFPMHGIB_02205 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_02206 1.56e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EFPMHGIB_02207 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EFPMHGIB_02208 4.95e-289 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EFPMHGIB_02209 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02210 7.35e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
EFPMHGIB_02211 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EFPMHGIB_02212 4.81e-124 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EFPMHGIB_02213 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EFPMHGIB_02214 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EFPMHGIB_02215 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EFPMHGIB_02216 1.62e-149 yuiC - - S - - - protein conserved in bacteria
EFPMHGIB_02217 1.14e-45 yuiB - - S - - - Putative membrane protein
EFPMHGIB_02218 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EFPMHGIB_02219 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EFPMHGIB_02221 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EFPMHGIB_02222 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
EFPMHGIB_02223 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_02224 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EFPMHGIB_02225 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EFPMHGIB_02226 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFPMHGIB_02227 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
EFPMHGIB_02228 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EFPMHGIB_02229 1.1e-73 yuzD - - S - - - protein conserved in bacteria
EFPMHGIB_02230 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EFPMHGIB_02231 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EFPMHGIB_02232 1.04e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EFPMHGIB_02233 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EFPMHGIB_02234 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EFPMHGIB_02235 1.55e-253 yutH - - S - - - Spore coat protein
EFPMHGIB_02236 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EFPMHGIB_02237 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EFPMHGIB_02238 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
EFPMHGIB_02239 3.2e-63 yutD - - S - - - protein conserved in bacteria
EFPMHGIB_02240 3.85e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EFPMHGIB_02241 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EFPMHGIB_02242 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EFPMHGIB_02243 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EFPMHGIB_02244 8.06e-64 yunC - - S - - - Domain of unknown function (DUF1805)
EFPMHGIB_02245 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EFPMHGIB_02246 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EFPMHGIB_02247 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
EFPMHGIB_02248 1.07e-79 yunG - - - - - - -
EFPMHGIB_02249 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EFPMHGIB_02250 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EFPMHGIB_02251 3.44e-299 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
EFPMHGIB_02252 4.52e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
EFPMHGIB_02253 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
EFPMHGIB_02254 1.47e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
EFPMHGIB_02255 6.95e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EFPMHGIB_02256 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EFPMHGIB_02257 2.76e-184 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EFPMHGIB_02258 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EFPMHGIB_02259 1.11e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EFPMHGIB_02261 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EFPMHGIB_02262 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EFPMHGIB_02263 1.8e-215 bsn - - L - - - Ribonuclease
EFPMHGIB_02264 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_02265 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EFPMHGIB_02266 5.31e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EFPMHGIB_02267 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EFPMHGIB_02268 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_02269 5.79e-307 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EFPMHGIB_02270 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EFPMHGIB_02271 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EFPMHGIB_02272 4.36e-263 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EFPMHGIB_02274 3.35e-56 - - - - - - - -
EFPMHGIB_02275 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EFPMHGIB_02276 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EFPMHGIB_02277 3.99e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFPMHGIB_02278 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EFPMHGIB_02279 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EFPMHGIB_02280 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFPMHGIB_02281 2.91e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EFPMHGIB_02282 2.64e-125 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EFPMHGIB_02283 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFPMHGIB_02284 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
EFPMHGIB_02285 5.73e-73 yusE - - CO - - - Thioredoxin
EFPMHGIB_02286 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EFPMHGIB_02287 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
EFPMHGIB_02288 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EFPMHGIB_02289 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EFPMHGIB_02290 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EFPMHGIB_02291 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EFPMHGIB_02292 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EFPMHGIB_02293 1.11e-13 - - - S - - - YuzL-like protein
EFPMHGIB_02294 2.84e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EFPMHGIB_02295 2.23e-54 - - - - - - - -
EFPMHGIB_02296 2.04e-68 yusN - - M - - - Coat F domain
EFPMHGIB_02297 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EFPMHGIB_02298 0.0 yusP - - P - - - Major facilitator superfamily
EFPMHGIB_02299 3.42e-84 yusQ - - S - - - Tautomerase enzyme
EFPMHGIB_02300 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02301 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
EFPMHGIB_02302 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
EFPMHGIB_02303 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EFPMHGIB_02304 3.48e-88 - - - S - - - YusW-like protein
EFPMHGIB_02305 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EFPMHGIB_02306 5.47e-197 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02307 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
EFPMHGIB_02308 9.21e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFPMHGIB_02309 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_02310 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02311 8.77e-204 yuxN - - K - - - Transcriptional regulator
EFPMHGIB_02312 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EFPMHGIB_02313 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
EFPMHGIB_02314 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EFPMHGIB_02315 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EFPMHGIB_02316 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EFPMHGIB_02317 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_02318 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02319 1.27e-162 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EFPMHGIB_02320 3.11e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EFPMHGIB_02321 8.16e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EFPMHGIB_02322 4.34e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EFPMHGIB_02323 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_02324 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EFPMHGIB_02325 3.76e-316 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EFPMHGIB_02326 6.35e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_02327 3.48e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
EFPMHGIB_02328 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02329 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EFPMHGIB_02330 0.0 yvrG - - T - - - Histidine kinase
EFPMHGIB_02331 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_02332 5.07e-32 - - - - - - - -
EFPMHGIB_02333 4.06e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EFPMHGIB_02334 3.46e-26 - - - S - - - YvrJ protein family
EFPMHGIB_02335 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EFPMHGIB_02336 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
EFPMHGIB_02337 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EFPMHGIB_02338 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02339 6.94e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
EFPMHGIB_02341 9.78e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EFPMHGIB_02342 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_02343 1.21e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_02344 1.09e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFPMHGIB_02345 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EFPMHGIB_02346 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EFPMHGIB_02347 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EFPMHGIB_02348 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EFPMHGIB_02349 5.98e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EFPMHGIB_02350 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EFPMHGIB_02351 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EFPMHGIB_02352 6.19e-201 yvgN - - S - - - reductase
EFPMHGIB_02353 7.97e-113 yvgO - - - - - - -
EFPMHGIB_02354 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EFPMHGIB_02355 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EFPMHGIB_02356 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EFPMHGIB_02357 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EFPMHGIB_02359 2.34e-139 yvgT - - S - - - membrane
EFPMHGIB_02360 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EFPMHGIB_02361 3.45e-137 bdbD - - O - - - Thioredoxin
EFPMHGIB_02362 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EFPMHGIB_02363 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EFPMHGIB_02364 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
EFPMHGIB_02365 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EFPMHGIB_02366 5.96e-249 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EFPMHGIB_02367 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EFPMHGIB_02368 1.43e-284 - - - S - - - Fusaric acid resistance protein-like
EFPMHGIB_02369 3.77e-117 - - - S - - - Fusaric acid resistance protein-like
EFPMHGIB_02370 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
EFPMHGIB_02371 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EFPMHGIB_02372 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
EFPMHGIB_02373 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02375 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EFPMHGIB_02376 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EFPMHGIB_02377 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EFPMHGIB_02378 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EFPMHGIB_02379 4.53e-193 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
EFPMHGIB_02380 3.44e-48 yvzC - - K - - - transcriptional
EFPMHGIB_02381 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EFPMHGIB_02382 4e-91 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EFPMHGIB_02383 3.85e-72 yvaP - - K - - - transcriptional
EFPMHGIB_02384 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_02385 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EFPMHGIB_02386 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EFPMHGIB_02387 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EFPMHGIB_02388 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EFPMHGIB_02389 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EFPMHGIB_02390 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EFPMHGIB_02391 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EFPMHGIB_02392 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EFPMHGIB_02393 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EFPMHGIB_02394 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EFPMHGIB_02395 2.66e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EFPMHGIB_02396 5.97e-145 yvbH - - S - - - YvbH-like oligomerisation region
EFPMHGIB_02397 1.61e-156 yvbI - - M - - - Membrane
EFPMHGIB_02398 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EFPMHGIB_02399 6.87e-106 yvbK - - K - - - acetyltransferase
EFPMHGIB_02400 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EFPMHGIB_02401 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EFPMHGIB_02402 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFPMHGIB_02403 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EFPMHGIB_02404 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFPMHGIB_02405 9.84e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EFPMHGIB_02406 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFPMHGIB_02407 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EFPMHGIB_02408 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_02410 5.49e-205 yvbU - - K - - - Transcriptional regulator
EFPMHGIB_02411 3.93e-198 yvbV - - EG - - - EamA-like transporter family
EFPMHGIB_02412 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_02413 1.22e-248 - - - S - - - Glycosyl hydrolase
EFPMHGIB_02414 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EFPMHGIB_02415 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EFPMHGIB_02416 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EFPMHGIB_02417 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_02418 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02419 4.81e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EFPMHGIB_02420 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EFPMHGIB_02421 1.71e-199 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
EFPMHGIB_02422 8.02e-261 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
EFPMHGIB_02423 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EFPMHGIB_02424 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
EFPMHGIB_02425 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EFPMHGIB_02426 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EFPMHGIB_02427 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EFPMHGIB_02428 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02429 1.18e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EFPMHGIB_02430 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EFPMHGIB_02431 9.59e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EFPMHGIB_02432 5.69e-44 yvfG - - S - - - YvfG protein
EFPMHGIB_02433 2.95e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EFPMHGIB_02434 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EFPMHGIB_02435 5.46e-75 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EFPMHGIB_02436 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EFPMHGIB_02437 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_02438 1.03e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_02439 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EFPMHGIB_02440 1e-247 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EFPMHGIB_02441 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EFPMHGIB_02442 1.5e-276 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EFPMHGIB_02443 1.25e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_02444 1.4e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EFPMHGIB_02445 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EFPMHGIB_02446 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EFPMHGIB_02447 6.82e-159 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EFPMHGIB_02448 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EFPMHGIB_02449 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EFPMHGIB_02451 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EFPMHGIB_02452 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
EFPMHGIB_02453 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EFPMHGIB_02454 0.0 pbpE - - V - - - Beta-lactamase
EFPMHGIB_02455 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EFPMHGIB_02456 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EFPMHGIB_02457 0.0 ybeC - - E - - - amino acid
EFPMHGIB_02458 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
EFPMHGIB_02459 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EFPMHGIB_02460 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EFPMHGIB_02461 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
EFPMHGIB_02462 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EFPMHGIB_02463 2.71e-233 - - - S - - - Patatin-like phospholipase
EFPMHGIB_02465 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EFPMHGIB_02466 1.41e-148 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EFPMHGIB_02467 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EFPMHGIB_02468 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
EFPMHGIB_02469 3.8e-195 malA - - S - - - Protein of unknown function (DUF1189)
EFPMHGIB_02470 2.67e-187 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
EFPMHGIB_02471 7.1e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
EFPMHGIB_02472 9.87e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
EFPMHGIB_02473 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
EFPMHGIB_02474 1.54e-221 yvdE - - K - - - Transcriptional regulator
EFPMHGIB_02475 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EFPMHGIB_02476 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EFPMHGIB_02477 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EFPMHGIB_02478 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EFPMHGIB_02479 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFPMHGIB_02480 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EFPMHGIB_02481 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02482 1.32e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
EFPMHGIB_02483 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_02484 1.37e-45 - - - - - - - -
EFPMHGIB_02485 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EFPMHGIB_02486 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EFPMHGIB_02487 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EFPMHGIB_02488 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EFPMHGIB_02489 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EFPMHGIB_02490 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EFPMHGIB_02491 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EFPMHGIB_02492 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EFPMHGIB_02493 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EFPMHGIB_02494 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EFPMHGIB_02496 0.0 - - - - - - - -
EFPMHGIB_02497 6.36e-172 - - - - - - - -
EFPMHGIB_02498 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EFPMHGIB_02499 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFPMHGIB_02500 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EFPMHGIB_02501 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFPMHGIB_02502 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EFPMHGIB_02503 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EFPMHGIB_02504 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EFPMHGIB_02505 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EFPMHGIB_02506 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
EFPMHGIB_02507 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
EFPMHGIB_02508 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EFPMHGIB_02509 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EFPMHGIB_02510 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
EFPMHGIB_02511 2.15e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFPMHGIB_02512 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFPMHGIB_02513 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFPMHGIB_02514 8.26e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFPMHGIB_02515 1.5e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EFPMHGIB_02516 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EFPMHGIB_02517 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_02518 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EFPMHGIB_02519 7.15e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
EFPMHGIB_02520 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_02521 1.42e-270 yvmA - - EGP - - - Major Facilitator Superfamily
EFPMHGIB_02522 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
EFPMHGIB_02523 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EFPMHGIB_02524 1.66e-220 yvlB - - S - - - Putative adhesin
EFPMHGIB_02525 8.09e-65 yvlA - - - - - - -
EFPMHGIB_02526 2.73e-46 yvkN - - - - - - -
EFPMHGIB_02527 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EFPMHGIB_02528 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EFPMHGIB_02529 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EFPMHGIB_02530 2.54e-42 csbA - - S - - - protein conserved in bacteria
EFPMHGIB_02531 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EFPMHGIB_02532 2.88e-131 yvkB - - K - - - Transcriptional regulator
EFPMHGIB_02533 2.13e-295 yvkA - - P - - - -transporter
EFPMHGIB_02534 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFPMHGIB_02535 1.38e-73 swrA - - S - - - Swarming motility protein
EFPMHGIB_02536 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EFPMHGIB_02537 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EFPMHGIB_02538 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EFPMHGIB_02539 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EFPMHGIB_02540 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EFPMHGIB_02541 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFPMHGIB_02542 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFPMHGIB_02543 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EFPMHGIB_02544 9.14e-88 - - - - - - - -
EFPMHGIB_02545 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EFPMHGIB_02546 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EFPMHGIB_02547 5.43e-314 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EFPMHGIB_02548 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
EFPMHGIB_02549 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EFPMHGIB_02550 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EFPMHGIB_02551 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EFPMHGIB_02552 6.92e-92 yviE - - - - - - -
EFPMHGIB_02553 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EFPMHGIB_02554 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EFPMHGIB_02555 7.06e-102 yvyG - - NOU - - - FlgN protein
EFPMHGIB_02556 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EFPMHGIB_02557 1.83e-96 yvyF - - S - - - flagellar protein
EFPMHGIB_02558 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EFPMHGIB_02559 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EFPMHGIB_02560 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFPMHGIB_02561 1.77e-198 degV - - S - - - protein conserved in bacteria
EFPMHGIB_02562 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_02563 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EFPMHGIB_02564 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EFPMHGIB_02565 4.43e-222 yvhJ - - K - - - Transcriptional regulator
EFPMHGIB_02566 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EFPMHGIB_02567 2.05e-297 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EFPMHGIB_02568 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EFPMHGIB_02569 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EFPMHGIB_02570 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EFPMHGIB_02571 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFPMHGIB_02572 1.34e-277 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EFPMHGIB_02573 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_02574 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EFPMHGIB_02575 4.54e-109 - - - M - - - Glycosyltransferase like family 2
EFPMHGIB_02576 6.43e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EFPMHGIB_02577 0.0 lytB - - D - - - Stage II sporulation protein
EFPMHGIB_02578 9.07e-16 - - - - - - - -
EFPMHGIB_02579 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EFPMHGIB_02580 2.21e-276 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EFPMHGIB_02581 1.48e-103 - - - M - - - Glycosyltransferase like family 2
EFPMHGIB_02582 5.45e-117 - - - M - - - Glycosyl transferases group 1
EFPMHGIB_02584 3.9e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EFPMHGIB_02585 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EFPMHGIB_02586 1.67e-168 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EFPMHGIB_02587 7.8e-102 - - - - - - - -
EFPMHGIB_02588 3.8e-68 - - - - - - - -
EFPMHGIB_02589 5.36e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EFPMHGIB_02590 4.14e-106 - - - M - - - Glycosyltransferase like family 2
EFPMHGIB_02591 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFPMHGIB_02592 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EFPMHGIB_02593 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EFPMHGIB_02594 4.07e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EFPMHGIB_02595 2.07e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EFPMHGIB_02596 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
EFPMHGIB_02597 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EFPMHGIB_02598 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EFPMHGIB_02599 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EFPMHGIB_02600 4.72e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EFPMHGIB_02601 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EFPMHGIB_02602 1.44e-255 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EFPMHGIB_02603 3.25e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EFPMHGIB_02604 6.46e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFPMHGIB_02605 1.22e-221 ywtF_2 - - K - - - Transcriptional regulator
EFPMHGIB_02606 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EFPMHGIB_02607 3.22e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EFPMHGIB_02608 4.62e-29 ywtC - - - - - - -
EFPMHGIB_02609 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EFPMHGIB_02610 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EFPMHGIB_02611 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EFPMHGIB_02612 1.55e-226 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
EFPMHGIB_02613 1.77e-204 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EFPMHGIB_02614 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EFPMHGIB_02615 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EFPMHGIB_02616 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EFPMHGIB_02617 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EFPMHGIB_02618 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
EFPMHGIB_02619 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
EFPMHGIB_02620 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EFPMHGIB_02621 5.26e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EFPMHGIB_02622 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EFPMHGIB_02623 3.36e-218 alsR - - K - - - LysR substrate binding domain
EFPMHGIB_02624 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EFPMHGIB_02625 2.5e-161 ywrJ - - - - - - -
EFPMHGIB_02626 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFPMHGIB_02627 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFPMHGIB_02628 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
EFPMHGIB_02629 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFPMHGIB_02630 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EFPMHGIB_02631 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EFPMHGIB_02632 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFPMHGIB_02633 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EFPMHGIB_02634 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFPMHGIB_02635 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EFPMHGIB_02636 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFPMHGIB_02637 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EFPMHGIB_02638 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EFPMHGIB_02639 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EFPMHGIB_02640 4.41e-96 - - - S - - - Bacterial PH domain
EFPMHGIB_02641 1.6e-171 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EFPMHGIB_02642 1.32e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EFPMHGIB_02643 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
EFPMHGIB_02644 5.34e-227 yyaD - - S - - - Membrane
EFPMHGIB_02645 7.41e-45 yyzM - - S - - - protein conserved in bacteria
EFPMHGIB_02646 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFPMHGIB_02647 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EFPMHGIB_02648 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EFPMHGIB_02649 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFPMHGIB_02650 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFPMHGIB_02651 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EFPMHGIB_02652 2.29e-225 ccpB - - K - - - Transcriptional regulator
EFPMHGIB_02653 2.32e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_02654 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
EFPMHGIB_02655 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
EFPMHGIB_02656 5.15e-216 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EFPMHGIB_02657 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EFPMHGIB_02658 1.26e-29 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EFPMHGIB_02659 3.21e-86 yrhP - - E - - - LysE type translocator
EFPMHGIB_02660 9.06e-27 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EFPMHGIB_02661 8.09e-207 - - - EG - - - EamA-like transporter family
EFPMHGIB_02662 1.34e-88 - - - K - - - MerR HTH family regulatory protein
EFPMHGIB_02663 1.57e-06 - - - S - - - Putative amidase domain
EFPMHGIB_02665 7.74e-312 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_02666 4.99e-136 yyaP - - H - - - RibD C-terminal domain
EFPMHGIB_02667 1.5e-85 - - - S - - - YjbR
EFPMHGIB_02668 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EFPMHGIB_02669 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
EFPMHGIB_02670 5.09e-91 yjcF - - S - - - Acetyltransferase (GNAT) domain
EFPMHGIB_02671 4.54e-100 yybA - - K - - - transcriptional
EFPMHGIB_02672 2.52e-163 - - - S - - - Metallo-beta-lactamase superfamily
EFPMHGIB_02673 4.25e-98 yybC - - - - - - -
EFPMHGIB_02674 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
EFPMHGIB_02675 1.53e-209 yybE - - K - - - Transcriptional regulator
EFPMHGIB_02676 7.78e-280 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_02677 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
EFPMHGIB_02678 5.02e-87 - - - S - - - SnoaL-like domain
EFPMHGIB_02679 1.01e-183 - - - - - - - -
EFPMHGIB_02680 4.38e-142 - - - K - - - TipAS antibiotic-recognition domain
EFPMHGIB_02681 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_02683 2.34e-92 - - - - - - - -
EFPMHGIB_02684 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EFPMHGIB_02685 1.11e-88 yybR - - K - - - Transcriptional regulator
EFPMHGIB_02686 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
EFPMHGIB_02688 1.5e-204 yybS - - S - - - membrane
EFPMHGIB_02689 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EFPMHGIB_02690 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EFPMHGIB_02691 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EFPMHGIB_02692 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EFPMHGIB_02693 1.89e-22 yycC - - K - - - YycC-like protein
EFPMHGIB_02695 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EFPMHGIB_02696 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EFPMHGIB_02697 2.32e-99 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_02698 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFPMHGIB_02703 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_02704 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02705 0.0 yycH - - S - - - protein conserved in bacteria
EFPMHGIB_02706 1.2e-200 yycI - - S - - - protein conserved in bacteria
EFPMHGIB_02707 3.29e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EFPMHGIB_02708 4.48e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EFPMHGIB_02709 1.4e-43 - - - S - - - Peptidase propeptide and YPEB domain
EFPMHGIB_02710 1.88e-97 - - - S - - - Peptidase propeptide and YPEB domain
EFPMHGIB_02711 6.75e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
EFPMHGIB_02712 5.27e-214 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EFPMHGIB_02713 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EFPMHGIB_02714 5.84e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EFPMHGIB_02715 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EFPMHGIB_02716 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EFPMHGIB_02718 1.75e-238 - - - S - - - aspartate phosphatase
EFPMHGIB_02719 9.43e-23 yycN - - K - - - Acetyltransferase
EFPMHGIB_02720 3.24e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EFPMHGIB_02721 3.79e-255 yycP - - - - - - -
EFPMHGIB_02722 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
EFPMHGIB_02724 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EFPMHGIB_02725 3.31e-89 - - - - - - - -
EFPMHGIB_02727 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFPMHGIB_02728 2.77e-202 - - - - - - - -
EFPMHGIB_02729 6.81e-120 - - - - - - - -
EFPMHGIB_02730 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EFPMHGIB_02731 1.44e-24 - - - - - - - -
EFPMHGIB_02732 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02733 1.52e-43 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
EFPMHGIB_02734 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EFPMHGIB_02735 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
EFPMHGIB_02736 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EFPMHGIB_02737 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EFPMHGIB_02738 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EFPMHGIB_02739 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EFPMHGIB_02740 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EFPMHGIB_02741 7.33e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
EFPMHGIB_02742 4.71e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EFPMHGIB_02743 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
EFPMHGIB_02744 1.27e-152 yxaC - - M - - - effector of murein hydrolase
EFPMHGIB_02745 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EFPMHGIB_02746 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_02747 5.01e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02748 2.75e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EFPMHGIB_02749 1.22e-249 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
EFPMHGIB_02750 4.19e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
EFPMHGIB_02751 4.03e-99 yxaI - - S - - - membrane protein domain
EFPMHGIB_02752 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
EFPMHGIB_02753 1.73e-135 yxaL - - S - - - PQQ-like domain
EFPMHGIB_02754 2.09e-16 yxaI - - S - - - membrane protein domain
EFPMHGIB_02755 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EFPMHGIB_02756 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EFPMHGIB_02757 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_02759 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EFPMHGIB_02760 3.41e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFPMHGIB_02761 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
EFPMHGIB_02763 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EFPMHGIB_02764 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EFPMHGIB_02765 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFPMHGIB_02766 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EFPMHGIB_02767 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EFPMHGIB_02768 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EFPMHGIB_02769 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EFPMHGIB_02770 1.99e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EFPMHGIB_02771 2.57e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EFPMHGIB_02772 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EFPMHGIB_02773 3.79e-187 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EFPMHGIB_02774 6.95e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EFPMHGIB_02775 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_02776 3.15e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_02777 3.01e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02778 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EFPMHGIB_02779 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
EFPMHGIB_02780 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EFPMHGIB_02781 9.65e-91 - - - - - - - -
EFPMHGIB_02782 7.57e-28 yxeD - - - - - - -
EFPMHGIB_02783 7.32e-42 yxeE - - - - - - -
EFPMHGIB_02786 8.09e-194 yxeH - - S - - - hydrolases of the HAD superfamily
EFPMHGIB_02787 1.29e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EFPMHGIB_02789 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_02790 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFPMHGIB_02791 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EFPMHGIB_02792 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EFPMHGIB_02793 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02794 1.17e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EFPMHGIB_02795 8.39e-314 yxeQ - - S - - - MmgE/PrpD family
EFPMHGIB_02796 1.74e-252 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
EFPMHGIB_02797 1.24e-195 - - - S - - - Domain of Unknown Function (DUF1206)
EFPMHGIB_02798 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EFPMHGIB_02799 3.38e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFPMHGIB_02800 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFPMHGIB_02801 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EFPMHGIB_02802 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EFPMHGIB_02803 3.41e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EFPMHGIB_02804 2.14e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EFPMHGIB_02805 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EFPMHGIB_02806 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EFPMHGIB_02807 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EFPMHGIB_02808 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EFPMHGIB_02809 1.26e-35 - - - S - - - Domain of unknown function (DUF5082)
EFPMHGIB_02810 1.89e-52 yxiC - - S - - - Family of unknown function (DUF5344)
EFPMHGIB_02811 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
EFPMHGIB_02812 7.61e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
EFPMHGIB_02813 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_02814 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EFPMHGIB_02815 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
EFPMHGIB_02816 2.52e-211 yxxF - - EG - - - EamA-like transporter family
EFPMHGIB_02817 7.6e-50 - - - - - - - -
EFPMHGIB_02818 4.67e-89 yxiG - - - - - - -
EFPMHGIB_02819 1.8e-162 - - - - - - - -
EFPMHGIB_02820 1.45e-107 yxiI - - S - - - Protein of unknown function (DUF2716)
EFPMHGIB_02821 1.94e-56 yxiJ - - S - - - YxiJ-like protein
EFPMHGIB_02824 2.28e-270 - - - E - - - GDSL-like Lipase/Acylhydrolase
EFPMHGIB_02825 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EFPMHGIB_02826 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EFPMHGIB_02827 5.09e-141 - - - - - - - -
EFPMHGIB_02828 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EFPMHGIB_02829 3.06e-184 bglS - - M - - - licheninase activity
EFPMHGIB_02830 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EFPMHGIB_02831 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EFPMHGIB_02832 2.28e-63 yxiS - - - - - - -
EFPMHGIB_02833 1.71e-132 - - - T - - - Domain of unknown function (DUF4163)
EFPMHGIB_02834 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EFPMHGIB_02835 1.2e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EFPMHGIB_02836 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
EFPMHGIB_02837 3.14e-166 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EFPMHGIB_02838 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EFPMHGIB_02839 5.59e-174 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EFPMHGIB_02840 3.81e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EFPMHGIB_02841 3.02e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EFPMHGIB_02842 9.66e-110 yxjI - - S - - - LURP-one-related
EFPMHGIB_02845 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EFPMHGIB_02846 5.83e-143 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
EFPMHGIB_02847 1.37e-258 - - - T - - - Signal transduction histidine kinase
EFPMHGIB_02848 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
EFPMHGIB_02849 8.3e-202 - - - K - - - LysR substrate binding domain
EFPMHGIB_02850 7.88e-121 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
EFPMHGIB_02851 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EFPMHGIB_02852 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
EFPMHGIB_02853 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EFPMHGIB_02854 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFPMHGIB_02855 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EFPMHGIB_02856 1.4e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EFPMHGIB_02857 3.05e-198 yxkH - - G - - - Polysaccharide deacetylase
EFPMHGIB_02859 0.0 - - - O - - - Peptidase family M48
EFPMHGIB_02860 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
EFPMHGIB_02861 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EFPMHGIB_02862 4.74e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EFPMHGIB_02863 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EFPMHGIB_02864 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EFPMHGIB_02865 9.16e-203 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EFPMHGIB_02866 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EFPMHGIB_02867 1.29e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_02868 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
EFPMHGIB_02869 2.92e-42 - - - - - - - -
EFPMHGIB_02870 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
EFPMHGIB_02871 5.52e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_02872 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFPMHGIB_02873 4.25e-200 yxlH - - EGP - - - Major Facilitator Superfamily
EFPMHGIB_02874 3.64e-56 yxlH - - EGP - - - Major Facilitator Superfamily
EFPMHGIB_02875 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EFPMHGIB_02876 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EFPMHGIB_02877 8.94e-28 yxzF - - - - - - -
EFPMHGIB_02878 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EFPMHGIB_02879 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EFPMHGIB_02880 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFPMHGIB_02881 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_02882 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EFPMHGIB_02883 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EFPMHGIB_02884 5.63e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EFPMHGIB_02885 4.78e-293 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFPMHGIB_02886 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_02887 3.26e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EFPMHGIB_02888 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_02889 4.89e-211 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EFPMHGIB_02890 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EFPMHGIB_02891 1.6e-164 - - - EGP - - - Permeases of the major facilitator superfamily
EFPMHGIB_02892 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
EFPMHGIB_02893 1.53e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
EFPMHGIB_02894 9.14e-317 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EFPMHGIB_02895 2.9e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFPMHGIB_02896 7.22e-114 ywaE - - K - - - Transcriptional regulator
EFPMHGIB_02897 2.11e-159 ywaF - - S - - - Integral membrane protein
EFPMHGIB_02898 5.37e-216 gspA - - M - - - General stress
EFPMHGIB_02899 3.03e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EFPMHGIB_02900 2.79e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_02901 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_02902 1.68e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFPMHGIB_02903 3.3e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EFPMHGIB_02904 3.29e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EFPMHGIB_02905 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EFPMHGIB_02906 4.13e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
EFPMHGIB_02907 1.21e-143 ywbG - - M - - - effector of murein hydrolase
EFPMHGIB_02908 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EFPMHGIB_02909 2.7e-203 ywbI - - K - - - Transcriptional regulator
EFPMHGIB_02910 3.79e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EFPMHGIB_02911 1.74e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EFPMHGIB_02912 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
EFPMHGIB_02913 1.4e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
EFPMHGIB_02914 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EFPMHGIB_02915 2.99e-140 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EFPMHGIB_02916 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFPMHGIB_02917 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
EFPMHGIB_02919 4.16e-159 ywcC - - K - - - transcriptional regulator
EFPMHGIB_02920 3.33e-77 gtcA - - S - - - GtrA-like protein
EFPMHGIB_02921 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFPMHGIB_02922 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EFPMHGIB_02923 5.11e-49 ydaS - - S - - - membrane
EFPMHGIB_02924 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EFPMHGIB_02925 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EFPMHGIB_02926 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EFPMHGIB_02927 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EFPMHGIB_02928 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EFPMHGIB_02929 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EFPMHGIB_02930 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EFPMHGIB_02931 1.4e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_02932 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_02934 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EFPMHGIB_02935 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
EFPMHGIB_02936 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_02937 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EFPMHGIB_02938 6.19e-39 ywdA - - - - - - -
EFPMHGIB_02939 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EFPMHGIB_02940 1.57e-190 ywdF - - S - - - Glycosyltransferase like family 2
EFPMHGIB_02941 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFPMHGIB_02942 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EFPMHGIB_02943 3.76e-64 ywdI - - S - - - Family of unknown function (DUF5327)
EFPMHGIB_02944 2.17e-302 ywdJ - - F - - - Xanthine uracil
EFPMHGIB_02945 1.59e-78 ywdK - - S - - - small membrane protein
EFPMHGIB_02946 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EFPMHGIB_02947 6.64e-186 spsA - - M - - - Spore Coat
EFPMHGIB_02948 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EFPMHGIB_02949 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EFPMHGIB_02950 1.72e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EFPMHGIB_02951 3.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EFPMHGIB_02952 1.01e-163 spsF - - M ko:K07257 - ko00000 Spore Coat
EFPMHGIB_02953 6.41e-237 spsG - - M - - - Spore Coat
EFPMHGIB_02954 2.5e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EFPMHGIB_02955 3.7e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EFPMHGIB_02956 1.41e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EFPMHGIB_02957 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EFPMHGIB_02958 3.7e-101 - - - - - - - -
EFPMHGIB_02959 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EFPMHGIB_02960 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EFPMHGIB_02961 0.0 rocB - - E - - - arginine degradation protein
EFPMHGIB_02962 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EFPMHGIB_02963 1.89e-275 ywfA - - EGP - - - -transporter
EFPMHGIB_02964 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EFPMHGIB_02965 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EFPMHGIB_02966 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_02967 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EFPMHGIB_02968 1.31e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EFPMHGIB_02969 1.82e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EFPMHGIB_02970 1.67e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_02971 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EFPMHGIB_02972 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EFPMHGIB_02973 1.25e-207 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_02974 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EFPMHGIB_02975 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
EFPMHGIB_02976 1.88e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EFPMHGIB_02977 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EFPMHGIB_02978 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EFPMHGIB_02979 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
EFPMHGIB_02980 8.67e-101 yffB - - K - - - Transcriptional regulator
EFPMHGIB_02981 4.41e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
EFPMHGIB_02983 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFPMHGIB_02984 1.76e-94 ywhA - - K - - - Transcriptional regulator
EFPMHGIB_02985 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EFPMHGIB_02986 3.29e-154 ywhC - - S - - - Peptidase family M50
EFPMHGIB_02987 7.83e-123 ywhD - - S - - - YwhD family
EFPMHGIB_02988 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EFPMHGIB_02989 5.52e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EFPMHGIB_02990 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EFPMHGIB_02992 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EFPMHGIB_02993 1.62e-282 ywhK - - CO - - - amine dehydrogenase activity
EFPMHGIB_02994 8.17e-316 ywhL - - CO - - - amine dehydrogenase activity
EFPMHGIB_02996 5.85e-316 - - - L - - - Peptidase, M16
EFPMHGIB_02997 2.42e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
EFPMHGIB_02998 8.41e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
EFPMHGIB_02999 2.49e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EFPMHGIB_03001 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
EFPMHGIB_03002 3.71e-12 - - - S - - - Bacteriocin subtilosin A
EFPMHGIB_03003 4.64e-96 ywiB - - S - - - protein conserved in bacteria
EFPMHGIB_03004 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EFPMHGIB_03005 1.2e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EFPMHGIB_03006 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EFPMHGIB_03007 1.51e-178 ywiC - - S - - - YwiC-like protein
EFPMHGIB_03008 2.39e-108 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EFPMHGIB_03009 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFPMHGIB_03010 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EFPMHGIB_03011 5.59e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EFPMHGIB_03012 2.41e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EFPMHGIB_03013 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFPMHGIB_03014 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EFPMHGIB_03015 6.52e-93 ywjB - - H - - - RibD C-terminal domain
EFPMHGIB_03016 1.32e-57 ywjC - - - - - - -
EFPMHGIB_03017 9.85e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EFPMHGIB_03018 4.74e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EFPMHGIB_03019 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EFPMHGIB_03020 1.65e-266 acdA - - I - - - acyl-CoA dehydrogenase
EFPMHGIB_03021 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EFPMHGIB_03022 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EFPMHGIB_03023 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
EFPMHGIB_03024 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EFPMHGIB_03025 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EFPMHGIB_03026 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EFPMHGIB_03027 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFPMHGIB_03028 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EFPMHGIB_03029 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EFPMHGIB_03030 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EFPMHGIB_03031 4.06e-134 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EFPMHGIB_03032 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EFPMHGIB_03033 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EFPMHGIB_03034 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EFPMHGIB_03035 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_03036 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFPMHGIB_03037 7.78e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EFPMHGIB_03039 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EFPMHGIB_03040 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EFPMHGIB_03041 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EFPMHGIB_03042 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EFPMHGIB_03043 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
EFPMHGIB_03044 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFPMHGIB_03045 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EFPMHGIB_03046 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
EFPMHGIB_03047 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFPMHGIB_03048 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFPMHGIB_03049 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EFPMHGIB_03050 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EFPMHGIB_03051 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFPMHGIB_03052 1.24e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EFPMHGIB_03053 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFPMHGIB_03054 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFPMHGIB_03055 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFPMHGIB_03056 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFPMHGIB_03057 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EFPMHGIB_03058 4.84e-112 ywmA - - - - - - -
EFPMHGIB_03059 4.54e-45 ywzB - - S - - - membrane
EFPMHGIB_03060 2.68e-171 ywmB - - S - - - TATA-box binding
EFPMHGIB_03061 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFPMHGIB_03062 3.41e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EFPMHGIB_03063 1.56e-156 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EFPMHGIB_03064 1.44e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EFPMHGIB_03066 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EFPMHGIB_03067 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EFPMHGIB_03068 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EFPMHGIB_03069 1.12e-109 ywmF - - S - - - Peptidase M50
EFPMHGIB_03070 1.11e-21 csbD - - K - - - CsbD-like
EFPMHGIB_03072 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EFPMHGIB_03073 7.55e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EFPMHGIB_03074 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EFPMHGIB_03075 4.58e-85 ywnA - - K - - - Transcriptional regulator
EFPMHGIB_03076 1.02e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EFPMHGIB_03077 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
EFPMHGIB_03078 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EFPMHGIB_03079 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFPMHGIB_03080 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
EFPMHGIB_03081 4.64e-22 ywnC - - S - - - Family of unknown function (DUF5362)
EFPMHGIB_03082 3.51e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EFPMHGIB_03083 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EFPMHGIB_03084 5.24e-92 ywnJ - - S - - - VanZ like family
EFPMHGIB_03085 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EFPMHGIB_03086 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EFPMHGIB_03087 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EFPMHGIB_03088 5.04e-101 - - - - - - - -
EFPMHGIB_03089 1.04e-133 yjgF - - Q - - - Isochorismatase family
EFPMHGIB_03090 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
EFPMHGIB_03091 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EFPMHGIB_03092 2.4e-311 ywoF - - P - - - Right handed beta helix region
EFPMHGIB_03093 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03094 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
EFPMHGIB_03095 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EFPMHGIB_03096 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EFPMHGIB_03097 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EFPMHGIB_03098 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EFPMHGIB_03099 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EFPMHGIB_03100 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFPMHGIB_03101 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EFPMHGIB_03102 1.28e-66 ywpD - - T - - - Histidine kinase
EFPMHGIB_03103 1.91e-87 ywpD - - T - - - Histidine kinase
EFPMHGIB_03104 1.55e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EFPMHGIB_03105 3.59e-88 ywpF - - S - - - YwpF-like protein
EFPMHGIB_03106 3.04e-87 ywpG - - - - - - -
EFPMHGIB_03107 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EFPMHGIB_03108 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EFPMHGIB_03109 8.76e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EFPMHGIB_03110 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EFPMHGIB_03111 0.0 ywqB - - S - - - SWIM zinc finger
EFPMHGIB_03112 3.6e-25 - - - - - - - -
EFPMHGIB_03113 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EFPMHGIB_03114 1.76e-153 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EFPMHGIB_03115 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EFPMHGIB_03116 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EFPMHGIB_03117 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
EFPMHGIB_03119 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
EFPMHGIB_03120 8.98e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
EFPMHGIB_03121 1.77e-26 - - - - - - - -
EFPMHGIB_03122 1.3e-23 - - - - - - - -
EFPMHGIB_03123 2.32e-99 ywqJ - - S - - - Pre-toxin TG
EFPMHGIB_03125 9.14e-152 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EFPMHGIB_03126 4.73e-209 - - - K - - - Transcriptional regulator
EFPMHGIB_03127 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
EFPMHGIB_03129 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EFPMHGIB_03130 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EFPMHGIB_03131 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EFPMHGIB_03132 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EFPMHGIB_03133 1.13e-70 - - - S - - - Domain of unknown function (DUF4181)
EFPMHGIB_03134 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFPMHGIB_03135 2.17e-16 - - - - - - - -
EFPMHGIB_03136 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
EFPMHGIB_03137 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
EFPMHGIB_03138 5.46e-74 ygzB - - S - - - UPF0295 protein
EFPMHGIB_03139 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EFPMHGIB_03140 3.41e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EFPMHGIB_03141 5.64e-313 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EFPMHGIB_03142 1.87e-238 ygaE - - S - - - Membrane
EFPMHGIB_03143 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EFPMHGIB_03144 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EFPMHGIB_03145 2.01e-49 ygaB - - S - - - YgaB-like protein
EFPMHGIB_03146 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EFPMHGIB_03147 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_03148 1.73e-48 yfhS - - - - - - -
EFPMHGIB_03149 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EFPMHGIB_03150 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EFPMHGIB_03151 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EFPMHGIB_03152 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_03153 3.93e-218 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
EFPMHGIB_03154 4.74e-62 yfhL - - S - - - SdpI/YhfL protein family
EFPMHGIB_03155 1.7e-117 yfhK - - T - - - Bacterial SH3 domain homologues
EFPMHGIB_03156 8.95e-60 yfhJ - - S - - - WVELL protein
EFPMHGIB_03157 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
EFPMHGIB_03158 9.96e-268 yfhI - - EGP - - - -transporter
EFPMHGIB_03159 1.32e-68 yfhH - - S - - - Protein of unknown function (DUF1811)
EFPMHGIB_03160 3.8e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EFPMHGIB_03161 1.54e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EFPMHGIB_03163 8.86e-35 yfhD - - S - - - YfhD-like protein
EFPMHGIB_03164 2.87e-138 yfhC - - C - - - nitroreductase
EFPMHGIB_03165 7.61e-215 yfhB - - S - - - PhzF family
EFPMHGIB_03166 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03167 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03168 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EFPMHGIB_03169 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFPMHGIB_03170 2.11e-103 yfiV - - K - - - transcriptional
EFPMHGIB_03171 0.0 yfiU - - EGP - - - the major facilitator superfamily
EFPMHGIB_03172 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EFPMHGIB_03173 8.95e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EFPMHGIB_03174 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EFPMHGIB_03175 1.89e-128 padR - - K - - - transcriptional
EFPMHGIB_03176 3.84e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EFPMHGIB_03177 1.46e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EFPMHGIB_03178 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_03179 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EFPMHGIB_03180 1.98e-271 baeS - - T - - - Histidine kinase
EFPMHGIB_03182 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EFPMHGIB_03183 3.34e-83 yfiD3 - - S - - - DoxX
EFPMHGIB_03184 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EFPMHGIB_03185 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EFPMHGIB_03186 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
EFPMHGIB_03187 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03188 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EFPMHGIB_03189 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EFPMHGIB_03190 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
EFPMHGIB_03191 6.91e-241 yfjB - - - - - - -
EFPMHGIB_03192 3.83e-161 yfjC - - - - - - -
EFPMHGIB_03193 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
EFPMHGIB_03194 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
EFPMHGIB_03195 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EFPMHGIB_03196 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EFPMHGIB_03197 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EFPMHGIB_03198 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFPMHGIB_03199 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFPMHGIB_03200 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EFPMHGIB_03201 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
EFPMHGIB_03202 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFPMHGIB_03203 1.45e-57 - - - S - - - YfzA-like protein
EFPMHGIB_03204 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFPMHGIB_03205 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EFPMHGIB_03206 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EFPMHGIB_03207 5.62e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EFPMHGIB_03208 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EFPMHGIB_03209 3.26e-36 yfjT - - - - - - -
EFPMHGIB_03210 1.76e-283 yfkA - - S - - - YfkB-like domain
EFPMHGIB_03211 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
EFPMHGIB_03212 3.69e-189 yfkD - - S - - - YfkD-like protein
EFPMHGIB_03213 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EFPMHGIB_03214 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03215 1.64e-12 - - - - - - - -
EFPMHGIB_03216 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EFPMHGIB_03217 1.03e-66 yfkI - - S - - - gas vesicle protein
EFPMHGIB_03218 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFPMHGIB_03219 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
EFPMHGIB_03220 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03221 2.71e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EFPMHGIB_03222 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EFPMHGIB_03223 5.27e-161 frp - - C - - - nitroreductase
EFPMHGIB_03224 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EFPMHGIB_03225 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EFPMHGIB_03226 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03227 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EFPMHGIB_03228 1.08e-269 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
EFPMHGIB_03230 4.23e-247 yfkT - - E ko:K06309 - ko00000 Spore germination protein
EFPMHGIB_03231 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
EFPMHGIB_03232 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EFPMHGIB_03233 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EFPMHGIB_03234 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EFPMHGIB_03235 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EFPMHGIB_03236 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
EFPMHGIB_03237 2.82e-26 yflI - - - - - - -
EFPMHGIB_03238 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
EFPMHGIB_03239 5.68e-156 yflK - - S - - - protein conserved in bacteria
EFPMHGIB_03240 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EFPMHGIB_03241 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EFPMHGIB_03242 1.4e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EFPMHGIB_03243 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EFPMHGIB_03244 1.14e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EFPMHGIB_03245 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EFPMHGIB_03246 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EFPMHGIB_03247 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EFPMHGIB_03248 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EFPMHGIB_03249 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
EFPMHGIB_03250 3.01e-31 - - - S - - - Protein of unknown function (DUF3212)
EFPMHGIB_03251 1.66e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EFPMHGIB_03252 1.65e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03253 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03254 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EFPMHGIB_03255 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
EFPMHGIB_03256 1.72e-268 - - - G - - - Major Facilitator Superfamily
EFPMHGIB_03257 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EFPMHGIB_03258 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
EFPMHGIB_03259 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EFPMHGIB_03260 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFPMHGIB_03261 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EFPMHGIB_03262 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EFPMHGIB_03263 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EFPMHGIB_03264 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EFPMHGIB_03265 5.14e-161 yfmS - - NT - - - chemotaxis protein
EFPMHGIB_03266 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFPMHGIB_03267 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
EFPMHGIB_03268 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EFPMHGIB_03269 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03270 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EFPMHGIB_03271 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
EFPMHGIB_03272 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EFPMHGIB_03273 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EFPMHGIB_03274 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EFPMHGIB_03275 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EFPMHGIB_03276 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EFPMHGIB_03277 3.5e-246 yetN - - S - - - Protein of unknown function (DUF3900)
EFPMHGIB_03278 2.57e-171 - - - M - - - Membrane
EFPMHGIB_03279 1.78e-265 yetM - - CH - - - FAD binding domain
EFPMHGIB_03280 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_03281 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EFPMHGIB_03282 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
EFPMHGIB_03283 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EFPMHGIB_03284 9.79e-45 - - - - - - - -
EFPMHGIB_03285 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EFPMHGIB_03286 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EFPMHGIB_03287 1.49e-156 yetF - - S - - - membrane
EFPMHGIB_03288 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EFPMHGIB_03289 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_03290 2.78e-225 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
EFPMHGIB_03291 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EFPMHGIB_03292 0.0 yetA - - - - - - -
EFPMHGIB_03293 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
EFPMHGIB_03294 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
EFPMHGIB_03295 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EFPMHGIB_03296 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
EFPMHGIB_03297 7.78e-143 - - - S - - - Protein of unknown function, DUF624
EFPMHGIB_03298 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
EFPMHGIB_03299 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
EFPMHGIB_03300 0.0 yesS - - K - - - Transcriptional regulator
EFPMHGIB_03301 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
EFPMHGIB_03302 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_03303 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EFPMHGIB_03304 2.39e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
EFPMHGIB_03305 2.31e-256 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
EFPMHGIB_03306 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_03307 8.56e-131 yesL - - S - - - Protein of unknown function, DUF624
EFPMHGIB_03309 1.39e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
EFPMHGIB_03310 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EFPMHGIB_03311 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
EFPMHGIB_03312 6.32e-59 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EFPMHGIB_03313 2.89e-194 yesF - - GM - - - NAD(P)H-binding
EFPMHGIB_03314 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
EFPMHGIB_03315 9.93e-130 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
EFPMHGIB_03317 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
EFPMHGIB_03319 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
EFPMHGIB_03320 4.02e-220 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
EFPMHGIB_03321 3.31e-203 - - - L - - - nucleic acid phosphodiester bond hydrolysis
EFPMHGIB_03322 1.26e-36 - - - - - - - -
EFPMHGIB_03324 9.55e-266 - - - V ko:K07451 - ko00000,ko01000,ko02048 Domain of unknown function (DUF3578)
EFPMHGIB_03325 1.3e-72 - - - - - - - -
EFPMHGIB_03326 8.55e-271 - - - T - - - Nacht domain
EFPMHGIB_03329 3.8e-24 - - - - - - - -
EFPMHGIB_03330 1.05e-190 - - - L - - - Recombinase zinc beta ribbon domain
EFPMHGIB_03331 4.82e-36 - - - L - - - Recombinase zinc beta ribbon domain
EFPMHGIB_03332 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFPMHGIB_03333 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFPMHGIB_03334 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EFPMHGIB_03335 1.47e-190 yerO - - K - - - Transcriptional regulator
EFPMHGIB_03336 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFPMHGIB_03337 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EFPMHGIB_03338 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFPMHGIB_03339 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFPMHGIB_03340 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EFPMHGIB_03341 1.48e-249 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EFPMHGIB_03342 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EFPMHGIB_03343 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFPMHGIB_03344 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EFPMHGIB_03345 9.04e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EFPMHGIB_03347 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EFPMHGIB_03348 7.62e-68 yerC - - S - - - protein conserved in bacteria
EFPMHGIB_03349 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EFPMHGIB_03350 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EFPMHGIB_03351 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
EFPMHGIB_03352 9.05e-296 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
EFPMHGIB_03353 2.51e-94 - - - K - - - helix_turn_helix ASNC type
EFPMHGIB_03354 3.29e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EFPMHGIB_03355 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EFPMHGIB_03356 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFPMHGIB_03357 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EFPMHGIB_03358 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EFPMHGIB_03359 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFPMHGIB_03360 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFPMHGIB_03361 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFPMHGIB_03362 2.04e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EFPMHGIB_03363 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFPMHGIB_03364 3.96e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFPMHGIB_03365 1.08e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFPMHGIB_03366 3.13e-38 yebG - - S - - - NETI protein
EFPMHGIB_03367 2.66e-120 yebE - - S - - - UPF0316 protein
EFPMHGIB_03369 2.38e-164 yebC - - M - - - Membrane
EFPMHGIB_03370 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EFPMHGIB_03371 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EFPMHGIB_03372 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EFPMHGIB_03373 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EFPMHGIB_03374 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EFPMHGIB_03375 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFPMHGIB_03376 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_03377 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EFPMHGIB_03378 1.96e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
EFPMHGIB_03379 1.25e-202 - - - I - - - Alpha/beta hydrolase family
EFPMHGIB_03380 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
EFPMHGIB_03382 4.44e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EFPMHGIB_03383 1.79e-84 ydjM - - M - - - Lytic transglycolase
EFPMHGIB_03384 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EFPMHGIB_03385 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFPMHGIB_03386 1.79e-244 - - - S - - - Ion transport 2 domain protein
EFPMHGIB_03387 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EFPMHGIB_03388 2.2e-174 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EFPMHGIB_03389 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFPMHGIB_03390 2.65e-146 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EFPMHGIB_03391 1.42e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EFPMHGIB_03392 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EFPMHGIB_03393 8.71e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EFPMHGIB_03394 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EFPMHGIB_03395 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
EFPMHGIB_03396 8.83e-123 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
EFPMHGIB_03397 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
EFPMHGIB_03398 1.12e-103 - - - V - - - Type I restriction modification DNA specificity domain
EFPMHGIB_03399 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
EFPMHGIB_03402 7.05e-293 - - - S - - - Bacterial EndoU nuclease
EFPMHGIB_03403 1.93e-53 - - - - - - - -
EFPMHGIB_03405 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EFPMHGIB_03406 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFPMHGIB_03407 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EFPMHGIB_03408 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EFPMHGIB_03409 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFPMHGIB_03410 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EFPMHGIB_03411 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFPMHGIB_03412 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EFPMHGIB_03413 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EFPMHGIB_03414 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFPMHGIB_03415 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EFPMHGIB_03416 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EFPMHGIB_03417 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EFPMHGIB_03418 1.63e-232 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EFPMHGIB_03421 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_03422 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EFPMHGIB_03423 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EFPMHGIB_03424 1.54e-288 - - - EGP - - - Major Facilitator Superfamily
EFPMHGIB_03425 2.1e-122 - - - S - - - YcxB-like protein
EFPMHGIB_03426 9.36e-205 ycxC - - EG - - - EamA-like transporter family
EFPMHGIB_03427 0.0 ycxD - - K - - - GntR family transcriptional regulator
EFPMHGIB_03428 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EFPMHGIB_03429 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
EFPMHGIB_03430 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EFPMHGIB_03431 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EFPMHGIB_03432 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EFPMHGIB_03433 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EFPMHGIB_03434 1.35e-141 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EFPMHGIB_03435 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EFPMHGIB_03436 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EFPMHGIB_03437 1.7e-106 yclD - - - - - - -
EFPMHGIB_03438 2.73e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
EFPMHGIB_03439 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EFPMHGIB_03440 0.0 yclG - - M - - - Pectate lyase superfamily protein
EFPMHGIB_03442 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
EFPMHGIB_03443 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
EFPMHGIB_03444 2.67e-253 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EFPMHGIB_03445 1.18e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EFPMHGIB_03446 1.07e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EFPMHGIB_03447 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_03448 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EFPMHGIB_03449 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EFPMHGIB_03451 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EFPMHGIB_03453 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EFPMHGIB_03454 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03455 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03456 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_03457 3.09e-217 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EFPMHGIB_03458 0.0 ycnB - - EGP - - - the major facilitator superfamily
EFPMHGIB_03459 5.87e-198 ycnC - - K - - - Transcriptional regulator
EFPMHGIB_03460 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EFPMHGIB_03461 1.68e-60 ycnE - - S - - - Monooxygenase
EFPMHGIB_03462 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EFPMHGIB_03463 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_03464 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EFPMHGIB_03465 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFPMHGIB_03466 3.37e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EFPMHGIB_03467 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_03468 3.28e-133 ycnI - - S - - - protein conserved in bacteria
EFPMHGIB_03469 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EFPMHGIB_03470 3.5e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EFPMHGIB_03471 9.44e-75 - - - - - - - -
EFPMHGIB_03472 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EFPMHGIB_03473 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EFPMHGIB_03474 5.13e-267 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EFPMHGIB_03475 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EFPMHGIB_03477 3.44e-94 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EFPMHGIB_03478 1.11e-139 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
EFPMHGIB_03479 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EFPMHGIB_03481 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EFPMHGIB_03482 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EFPMHGIB_03483 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EFPMHGIB_03484 2.01e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EFPMHGIB_03485 1.19e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EFPMHGIB_03486 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EFPMHGIB_03487 1.55e-170 kipR - - K - - - Transcriptional regulator
EFPMHGIB_03488 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EFPMHGIB_03490 8.97e-65 yczJ - - S - - - biosynthesis
EFPMHGIB_03491 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EFPMHGIB_03492 8.6e-220 ycsN - - S - - - Oxidoreductase
EFPMHGIB_03493 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EFPMHGIB_03494 0.0 ydaB - - IQ - - - acyl-CoA ligase
EFPMHGIB_03495 6.05e-129 ydaC - - Q - - - Methyltransferase domain
EFPMHGIB_03496 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFPMHGIB_03497 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EFPMHGIB_03498 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EFPMHGIB_03499 5.24e-101 ydaG - - S - - - general stress protein
EFPMHGIB_03500 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EFPMHGIB_03501 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EFPMHGIB_03502 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EFPMHGIB_03503 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFPMHGIB_03504 2.96e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EFPMHGIB_03505 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EFPMHGIB_03506 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EFPMHGIB_03507 7.86e-304 ydaM - - M - - - Glycosyl transferase family group 2
EFPMHGIB_03508 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EFPMHGIB_03509 0.0 ydaO - - E - - - amino acid
EFPMHGIB_03510 3.08e-102 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EFPMHGIB_03511 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EFPMHGIB_03512 2.14e-53 - - - - - - - -
EFPMHGIB_03513 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EFPMHGIB_03514 1.67e-42 ydaS - - S - - - membrane
EFPMHGIB_03515 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EFPMHGIB_03516 1.06e-190 ydbA - - P - - - EcsC protein family
EFPMHGIB_03517 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
EFPMHGIB_03518 7.58e-79 ydbB - - G - - - Cupin domain
EFPMHGIB_03519 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
EFPMHGIB_03520 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
EFPMHGIB_03521 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EFPMHGIB_03522 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EFPMHGIB_03523 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EFPMHGIB_03524 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFPMHGIB_03525 3.25e-231 ydbI - - S - - - AI-2E family transporter
EFPMHGIB_03526 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_03527 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EFPMHGIB_03528 9.32e-70 ydbL - - - - - - -
EFPMHGIB_03529 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
EFPMHGIB_03530 1.49e-26 - - - S - - - Fur-regulated basic protein B
EFPMHGIB_03532 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFPMHGIB_03533 4.19e-75 ydbP - - CO - - - Thioredoxin
EFPMHGIB_03534 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EFPMHGIB_03535 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EFPMHGIB_03536 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EFPMHGIB_03537 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EFPMHGIB_03538 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EFPMHGIB_03539 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EFPMHGIB_03540 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EFPMHGIB_03541 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EFPMHGIB_03542 1.39e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFPMHGIB_03543 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EFPMHGIB_03544 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EFPMHGIB_03545 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EFPMHGIB_03546 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EFPMHGIB_03547 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EFPMHGIB_03548 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EFPMHGIB_03549 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EFPMHGIB_03550 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EFPMHGIB_03551 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EFPMHGIB_03552 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EFPMHGIB_03553 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EFPMHGIB_03554 2.17e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EFPMHGIB_03562 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
EFPMHGIB_03563 2.85e-58 - - - - - - - -
EFPMHGIB_03564 3.85e-24 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
EFPMHGIB_03565 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
EFPMHGIB_03566 9.05e-56 - - - L - - - HNH nucleases
EFPMHGIB_03569 7.24e-08 - - - S - - - Putative amidase domain
EFPMHGIB_03572 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
EFPMHGIB_03573 6e-53 - - - - - - - -
EFPMHGIB_03577 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
EFPMHGIB_03578 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EFPMHGIB_03579 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
EFPMHGIB_03580 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFPMHGIB_03581 2.18e-213 - - - K - - - AraC-like ligand binding domain
EFPMHGIB_03582 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFPMHGIB_03583 4.06e-209 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EFPMHGIB_03584 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_03585 3.8e-277 ydeG - - EGP - - - Major facilitator superfamily
EFPMHGIB_03586 9.2e-70 ydeH - - - - - - -
EFPMHGIB_03587 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
EFPMHGIB_03588 4.54e-41 - - - - - - - -
EFPMHGIB_03589 2.91e-66 - - - - - - - -
EFPMHGIB_03590 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
EFPMHGIB_03591 5.54e-146 - - - T - - - Transcriptional regulator
EFPMHGIB_03592 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
EFPMHGIB_03593 6.97e-93 - - - S - - - SNARE associated Golgi protein
EFPMHGIB_03594 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
EFPMHGIB_03595 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
EFPMHGIB_03596 1.49e-193 ydeK - - EG - - - -transporter
EFPMHGIB_03597 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_03598 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
EFPMHGIB_03599 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
EFPMHGIB_03600 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
EFPMHGIB_03601 9.73e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EFPMHGIB_03602 1.32e-255 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EFPMHGIB_03603 1.78e-134 ydeS - - K - - - Transcriptional regulator
EFPMHGIB_03604 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EFPMHGIB_03605 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EFPMHGIB_03606 1.28e-187 - - - J - - - GNAT acetyltransferase
EFPMHGIB_03607 5.77e-196 - - - EG - - - EamA-like transporter family
EFPMHGIB_03608 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFPMHGIB_03609 6.97e-150 ydfE - - S - - - Flavin reductase like domain
EFPMHGIB_03610 2.13e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EFPMHGIB_03611 3.77e-102 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EFPMHGIB_03613 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_03614 9.37e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFPMHGIB_03615 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EFPMHGIB_03616 4.97e-219 - - - S - - - Alpha/beta hydrolase family
EFPMHGIB_03617 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
EFPMHGIB_03618 6.84e-186 - - - K - - - Bacterial transcription activator, effector binding domain
EFPMHGIB_03619 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFPMHGIB_03620 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EFPMHGIB_03621 9.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EFPMHGIB_03622 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
EFPMHGIB_03623 3.78e-74 ydfQ - - CO - - - Thioredoxin
EFPMHGIB_03624 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
EFPMHGIB_03625 5.33e-39 - - - - - - - -
EFPMHGIB_03627 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
EFPMHGIB_03628 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
EFPMHGIB_03629 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EFPMHGIB_03630 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
EFPMHGIB_03631 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
EFPMHGIB_03632 5.99e-130 ydgC - - K - - - Bacterial regulatory proteins, tetR family
EFPMHGIB_03633 7e-71 - - - S - - - DoxX-like family
EFPMHGIB_03634 2.49e-114 yycN - - K - - - Acetyltransferase
EFPMHGIB_03635 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EFPMHGIB_03636 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_03637 5.94e-118 - - - S - - - DinB family
EFPMHGIB_03638 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_03639 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EFPMHGIB_03640 6.42e-147 ydgI - - C - - - nitroreductase
EFPMHGIB_03641 3.29e-90 - - - K - - - Winged helix DNA-binding domain
EFPMHGIB_03642 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EFPMHGIB_03643 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EFPMHGIB_03644 5.24e-158 ydhC - - K - - - FCD
EFPMHGIB_03645 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
EFPMHGIB_03646 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EFPMHGIB_03647 5e-162 - - - - - - - -
EFPMHGIB_03648 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EFPMHGIB_03649 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EFPMHGIB_03651 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
EFPMHGIB_03652 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
EFPMHGIB_03653 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
EFPMHGIB_03654 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EFPMHGIB_03655 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03656 5.86e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03657 9.72e-301 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFPMHGIB_03658 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EFPMHGIB_03659 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EFPMHGIB_03660 8.91e-217 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EFPMHGIB_03661 4.19e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EFPMHGIB_03662 1.86e-268 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EFPMHGIB_03663 3.44e-202 ydhU - - P ko:K07217 - ko00000 Catalase
EFPMHGIB_03667 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_03668 6.05e-86 hxlR - - K - - - transcriptional
EFPMHGIB_03669 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EFPMHGIB_03670 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EFPMHGIB_03671 1.52e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EFPMHGIB_03672 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
EFPMHGIB_03673 4.78e-91 nin - - S - - - Competence protein J (ComJ)
EFPMHGIB_03674 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EFPMHGIB_03675 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
EFPMHGIB_03676 1.29e-95 yckC - - S - - - membrane
EFPMHGIB_03678 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFPMHGIB_03679 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EFPMHGIB_03680 6.78e-291 yciC - - S - - - GTPases (G3E family)
EFPMHGIB_03681 9.38e-132 - - - M - - - ErfK YbiS YcfS YnhG
EFPMHGIB_03682 3.23e-217 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
EFPMHGIB_03683 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EFPMHGIB_03684 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
EFPMHGIB_03685 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EFPMHGIB_03686 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EFPMHGIB_03687 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EFPMHGIB_03688 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EFPMHGIB_03689 2.01e-243 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EFPMHGIB_03690 1.34e-199 ycgS - - I - - - alpha/beta hydrolase fold
EFPMHGIB_03691 2.62e-186 ycgR - - S ko:K07089 - ko00000 permeases
EFPMHGIB_03692 3.03e-193 ycgQ - - S ko:K08986 - ko00000 membrane
EFPMHGIB_03693 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EFPMHGIB_03694 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EFPMHGIB_03695 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EFPMHGIB_03696 2.1e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EFPMHGIB_03697 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EFPMHGIB_03698 2.7e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EFPMHGIB_03699 8.01e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
EFPMHGIB_03700 1.51e-185 - - - Q - - - ubiE/COQ5 methyltransferase family
EFPMHGIB_03701 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFPMHGIB_03703 3.09e-139 tmrB - - S - - - AAA domain
EFPMHGIB_03704 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EFPMHGIB_03705 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EFPMHGIB_03706 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_03707 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EFPMHGIB_03708 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
EFPMHGIB_03709 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EFPMHGIB_03710 0.0 mdr - - EGP - - - the major facilitator superfamily
EFPMHGIB_03711 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EFPMHGIB_03712 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EFPMHGIB_03713 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
EFPMHGIB_03714 7.79e-105 ycgB - - - - - - -
EFPMHGIB_03715 0.0 ycgA - - S - - - Membrane
EFPMHGIB_03716 6.87e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EFPMHGIB_03717 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EFPMHGIB_03718 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EFPMHGIB_03719 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EFPMHGIB_03720 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EFPMHGIB_03721 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
EFPMHGIB_03722 9.03e-277 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EFPMHGIB_03723 2.96e-245 yceH - - P - - - Belongs to the TelA family
EFPMHGIB_03724 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EFPMHGIB_03725 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EFPMHGIB_03726 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EFPMHGIB_03727 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EFPMHGIB_03728 1.78e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EFPMHGIB_03729 4.01e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFPMHGIB_03730 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EFPMHGIB_03731 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EFPMHGIB_03732 1.86e-219 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EFPMHGIB_03733 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EFPMHGIB_03734 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EFPMHGIB_03735 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EFPMHGIB_03736 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EFPMHGIB_03737 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_03738 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_03739 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
EFPMHGIB_03740 7.95e-221 yccK - - C - - - Aldo keto reductase
EFPMHGIB_03741 4.43e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EFPMHGIB_03742 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
EFPMHGIB_03743 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
EFPMHGIB_03744 1.69e-210 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
EFPMHGIB_03745 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
EFPMHGIB_03746 1.14e-73 - - - S - - - RDD family
EFPMHGIB_03747 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EFPMHGIB_03748 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EFPMHGIB_03749 1.04e-128 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EFPMHGIB_03750 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EFPMHGIB_03751 5.92e-260 ycbU - - E - - - Selenocysteine lyase
EFPMHGIB_03752 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EFPMHGIB_03753 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFPMHGIB_03754 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EFPMHGIB_03755 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EFPMHGIB_03756 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
EFPMHGIB_03757 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EFPMHGIB_03758 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
EFPMHGIB_03759 4.75e-147 - - - S - - - ABC-2 family transporter protein
EFPMHGIB_03760 2.64e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EFPMHGIB_03761 6.48e-216 ycbM - - T - - - Histidine kinase
EFPMHGIB_03762 3.05e-159 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFPMHGIB_03763 4.43e-131 eamA1 - - EG - - - spore germination
EFPMHGIB_03764 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EFPMHGIB_03765 6.33e-225 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EFPMHGIB_03766 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EFPMHGIB_03767 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
EFPMHGIB_03768 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EFPMHGIB_03769 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03770 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EFPMHGIB_03771 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
EFPMHGIB_03772 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EFPMHGIB_03773 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EFPMHGIB_03774 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EFPMHGIB_03775 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EFPMHGIB_03776 9.76e-229 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EFPMHGIB_03777 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EFPMHGIB_03778 3.08e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EFPMHGIB_03780 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EFPMHGIB_03781 1.43e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFPMHGIB_03782 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03783 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFPMHGIB_03784 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EFPMHGIB_03785 1.58e-59 ybfN - - - - - - -
EFPMHGIB_03786 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EFPMHGIB_03787 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
EFPMHGIB_03788 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFPMHGIB_03789 2.02e-216 - - - S - - - Alpha/beta hydrolase family
EFPMHGIB_03791 1.44e-229 mpr - - M - - - Belongs to the peptidase S1B family
EFPMHGIB_03792 2.18e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EFPMHGIB_03793 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
EFPMHGIB_03794 3.05e-207 ybfH - - EG - - - EamA-like transporter family
EFPMHGIB_03795 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
EFPMHGIB_03797 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
EFPMHGIB_03798 2.1e-218 ybfA - - K - - - FR47-like protein
EFPMHGIB_03799 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
EFPMHGIB_03800 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EFPMHGIB_03801 2.85e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EFPMHGIB_03802 0.0 ybeC - - E - - - amino acid
EFPMHGIB_03803 1.11e-54 ybyB - - - - - - -
EFPMHGIB_03804 8.58e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EFPMHGIB_03805 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
EFPMHGIB_03806 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
EFPMHGIB_03807 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EFPMHGIB_03808 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EFPMHGIB_03809 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
EFPMHGIB_03810 7.4e-193 ybdN - - - - - - -
EFPMHGIB_03811 3.26e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
EFPMHGIB_03813 1.61e-218 - - - T - - - His Kinase A (phospho-acceptor) domain
EFPMHGIB_03814 3.28e-156 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
EFPMHGIB_03815 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFPMHGIB_03816 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EFPMHGIB_03818 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
EFPMHGIB_03819 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
EFPMHGIB_03820 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EFPMHGIB_03822 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
EFPMHGIB_03823 9.45e-67 - - - K - - - Helix-turn-helix domain
EFPMHGIB_03824 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
EFPMHGIB_03825 1.6e-63 - - - - - - - -
EFPMHGIB_03827 4.01e-120 ybcF - - P - - - carbonic anhydrase
EFPMHGIB_03828 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
EFPMHGIB_03829 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EFPMHGIB_03830 5.25e-127 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EFPMHGIB_03831 1.52e-153 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EFPMHGIB_03832 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EFPMHGIB_03833 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EFPMHGIB_03834 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFPMHGIB_03835 3.41e-291 ybbR - - S - - - protein conserved in bacteria
EFPMHGIB_03836 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFPMHGIB_03837 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EFPMHGIB_03838 7.62e-126 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EFPMHGIB_03844 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
EFPMHGIB_03845 1.81e-113 ybbJ - - J - - - acetyltransferase
EFPMHGIB_03846 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EFPMHGIB_03847 3.01e-191 ybbH - - K - - - transcriptional
EFPMHGIB_03848 5.99e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EFPMHGIB_03849 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EFPMHGIB_03850 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EFPMHGIB_03851 8.14e-303 ybbC - - S - - - protein conserved in bacteria
EFPMHGIB_03852 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EFPMHGIB_03853 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EFPMHGIB_03854 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03855 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFPMHGIB_03856 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
EFPMHGIB_03857 5.36e-203 ybaS - - S - - - Na -dependent transporter
EFPMHGIB_03859 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EFPMHGIB_03866 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
EFPMHGIB_03867 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EFPMHGIB_03868 8.37e-259 yaaN - - P - - - Belongs to the TelA family
EFPMHGIB_03869 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EFPMHGIB_03870 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFPMHGIB_03871 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
EFPMHGIB_03872 2.1e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EFPMHGIB_03873 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EFPMHGIB_03874 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
EFPMHGIB_03875 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
EFPMHGIB_03876 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EFPMHGIB_03877 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EFPMHGIB_03878 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFPMHGIB_03879 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EFPMHGIB_03880 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFPMHGIB_03881 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EFPMHGIB_03882 1.18e-277 yabE - - T - - - protein conserved in bacteria
EFPMHGIB_03883 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFPMHGIB_03884 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EFPMHGIB_03885 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
EFPMHGIB_03886 5.32e-53 veg - - S - - - protein conserved in bacteria
EFPMHGIB_03887 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
EFPMHGIB_03888 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EFPMHGIB_03889 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EFPMHGIB_03890 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EFPMHGIB_03891 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EFPMHGIB_03892 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFPMHGIB_03893 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFPMHGIB_03894 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EFPMHGIB_03895 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EFPMHGIB_03896 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
EFPMHGIB_03897 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFPMHGIB_03898 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EFPMHGIB_03899 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EFPMHGIB_03900 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EFPMHGIB_03901 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EFPMHGIB_03902 1.91e-66 yabP - - S - - - Sporulation protein YabP
EFPMHGIB_03903 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
EFPMHGIB_03904 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EFPMHGIB_03905 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EFPMHGIB_03908 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EFPMHGIB_03909 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EFPMHGIB_03910 5.08e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EFPMHGIB_03911 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EFPMHGIB_03912 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EFPMHGIB_03913 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFPMHGIB_03914 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EFPMHGIB_03915 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFPMHGIB_03916 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EFPMHGIB_03917 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EFPMHGIB_03918 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFPMHGIB_03919 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EFPMHGIB_03920 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EFPMHGIB_03921 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EFPMHGIB_03922 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFPMHGIB_03923 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFPMHGIB_03924 1.81e-41 yazB - - K - - - transcriptional
EFPMHGIB_03925 9.2e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFPMHGIB_03926 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EFPMHGIB_03927 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EFPMHGIB_03928 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_03929 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_03931 2.14e-232 yaaC - - S - - - YaaC-like Protein
EFPMHGIB_03932 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EFPMHGIB_03933 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EFPMHGIB_03934 1.06e-201 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EFPMHGIB_03935 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EFPMHGIB_03936 2.3e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFPMHGIB_03938 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EFPMHGIB_03939 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EFPMHGIB_03940 2.57e-276 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EFPMHGIB_03941 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EFPMHGIB_03942 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EFPMHGIB_03943 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFPMHGIB_03944 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFPMHGIB_03945 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFPMHGIB_03946 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
EFPMHGIB_03947 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EFPMHGIB_03948 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFPMHGIB_03949 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
EFPMHGIB_03950 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
EFPMHGIB_03951 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EFPMHGIB_03952 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EFPMHGIB_03953 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EFPMHGIB_03954 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EFPMHGIB_03955 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EFPMHGIB_03956 4.54e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EFPMHGIB_03957 4.25e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EFPMHGIB_03958 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EFPMHGIB_03959 5.83e-293 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
EFPMHGIB_03960 2.01e-134 yngC - - S - - - membrane-associated protein
EFPMHGIB_03961 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EFPMHGIB_03962 2.45e-103 yngA - - S - - - membrane
EFPMHGIB_03963 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EFPMHGIB_03964 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
EFPMHGIB_03966 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
EFPMHGIB_03967 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EFPMHGIB_03968 1.06e-75 ynfC - - - - - - -
EFPMHGIB_03969 1.82e-18 - - - - - - - -
EFPMHGIB_03970 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFPMHGIB_03971 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFPMHGIB_03972 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EFPMHGIB_03973 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EFPMHGIB_03974 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
EFPMHGIB_03975 5.48e-70 yneQ - - - - - - -
EFPMHGIB_03976 5.7e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EFPMHGIB_03977 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EFPMHGIB_03979 9.26e-10 - - - S - - - Fur-regulated basic protein B
EFPMHGIB_03980 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EFPMHGIB_03981 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EFPMHGIB_03982 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EFPMHGIB_03983 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EFPMHGIB_03984 2.35e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
EFPMHGIB_03985 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
EFPMHGIB_03986 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EFPMHGIB_03987 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EFPMHGIB_03988 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EFPMHGIB_03989 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
EFPMHGIB_03990 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EFPMHGIB_03991 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EFPMHGIB_03992 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFPMHGIB_03993 1.15e-43 ynzC - - S - - - UPF0291 protein
EFPMHGIB_03994 2.29e-144 yneB - - L - - - resolvase
EFPMHGIB_03995 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EFPMHGIB_03996 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EFPMHGIB_03997 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EFPMHGIB_03998 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
EFPMHGIB_03999 3.26e-175 yndL - - S - - - Replication protein
EFPMHGIB_04001 0.0 yndJ - - S - - - YndJ-like protein
EFPMHGIB_04002 6.98e-149 - - - S - - - Domain of unknown function (DUF4166)
EFPMHGIB_04003 2.52e-196 yndG - - S - - - DoxX-like family
EFPMHGIB_04004 2.27e-288 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
EFPMHGIB_04005 7.36e-75 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
EFPMHGIB_04006 6.99e-157 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
EFPMHGIB_04007 7e-47 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EFPMHGIB_04011 1.49e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EFPMHGIB_04012 7.34e-95 - - - - - - - -
EFPMHGIB_04013 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
EFPMHGIB_04016 1.73e-169 - - - S - - - Domain of unknown function, YrpD
EFPMHGIB_04017 9.21e-209 - - - S - - - Thymidylate synthase
EFPMHGIB_04020 7.54e-22 - - - - - - - -
EFPMHGIB_04021 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EFPMHGIB_04022 9.48e-108 - - - S - - - Protein of unknown function (DUF2691)
EFPMHGIB_04023 2.93e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFPMHGIB_04024 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EFPMHGIB_04025 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
EFPMHGIB_04026 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EFPMHGIB_04027 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EFPMHGIB_04028 5.85e-274 xylR - - GK - - - ROK family
EFPMHGIB_04029 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EFPMHGIB_04030 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EFPMHGIB_04031 9.04e-97 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
EFPMHGIB_04032 6.36e-103 - - - E - - - phosphoribosylanthranilate isomerase activity
EFPMHGIB_04035 1.39e-145 - - - S - - - Domain of unknown function (DUF3885)
EFPMHGIB_04036 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EFPMHGIB_04037 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EFPMHGIB_04038 2.28e-93 - - - S - - - CAAX protease self-immunity
EFPMHGIB_04040 7.11e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
EFPMHGIB_04042 3.49e-271 - - - H - - - N-terminal domain of galactosyltransferase
EFPMHGIB_04043 6.07e-248 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EFPMHGIB_04044 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
EFPMHGIB_04045 9.6e-120 - - - M - - - Glycosyltransferase like family
EFPMHGIB_04046 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EFPMHGIB_04047 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EFPMHGIB_04048 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EFPMHGIB_04049 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EFPMHGIB_04050 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFPMHGIB_04051 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EFPMHGIB_04052 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EFPMHGIB_04053 8.66e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EFPMHGIB_04054 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EFPMHGIB_04055 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFPMHGIB_04056 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EFPMHGIB_04057 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EFPMHGIB_04058 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFPMHGIB_04059 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFPMHGIB_04060 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EFPMHGIB_04061 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EFPMHGIB_04062 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EFPMHGIB_04063 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EFPMHGIB_04064 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFPMHGIB_04065 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EFPMHGIB_04066 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFPMHGIB_04067 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EFPMHGIB_04068 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EFPMHGIB_04069 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFPMHGIB_04070 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFPMHGIB_04071 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EFPMHGIB_04072 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFPMHGIB_04073 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EFPMHGIB_04074 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFPMHGIB_04075 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFPMHGIB_04076 8.32e-227 ybaC - - S - - - Alpha/beta hydrolase family
EFPMHGIB_04077 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EFPMHGIB_04078 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFPMHGIB_04079 7.98e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EFPMHGIB_04080 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EFPMHGIB_04081 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFPMHGIB_04082 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFPMHGIB_04083 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFPMHGIB_04084 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFPMHGIB_04085 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFPMHGIB_04086 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EFPMHGIB_04087 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFPMHGIB_04088 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFPMHGIB_04089 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFPMHGIB_04090 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFPMHGIB_04091 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFPMHGIB_04092 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFPMHGIB_04093 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFPMHGIB_04094 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFPMHGIB_04095 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFPMHGIB_04096 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EFPMHGIB_04097 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EFPMHGIB_04098 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EFPMHGIB_04099 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EFPMHGIB_04100 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EFPMHGIB_04101 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFPMHGIB_04102 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EFPMHGIB_04103 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFPMHGIB_04104 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFPMHGIB_04105 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFPMHGIB_04106 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EFPMHGIB_04107 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFPMHGIB_04108 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFPMHGIB_04109 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFPMHGIB_04110 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EFPMHGIB_04111 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFPMHGIB_04112 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EFPMHGIB_04113 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
EFPMHGIB_04114 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
EFPMHGIB_04115 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EFPMHGIB_04116 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EFPMHGIB_04117 1.04e-122 gerD - - - ko:K06294 - ko00000 -
EFPMHGIB_04118 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EFPMHGIB_04119 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
EFPMHGIB_04120 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)