ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
FMFMHKIL_00001 3.21e-49 - - - O - - - Glutaredoxin
FMFMHKIL_00002 4.35e-125 - - - L - - - HNH endonuclease
FMFMHKIL_00003 1.44e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMFMHKIL_00005 1.88e-251 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMFMHKIL_00006 3.83e-43 - - - L - - - GIY-YIG catalytic domain
FMFMHKIL_00007 1.15e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMFMHKIL_00008 3.12e-82 - - - S - - - NrdI Flavodoxin like
FMFMHKIL_00027 4.69e-95 - - - L - - - DNA methylase
FMFMHKIL_00028 2.42e-117 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FMFMHKIL_00029 1.47e-110 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
FMFMHKIL_00034 1.09e-136 - - - S - - - protein conserved in bacteria
FMFMHKIL_00035 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
FMFMHKIL_00036 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
FMFMHKIL_00037 7.79e-285 - - - L - - - DNA primase activity
FMFMHKIL_00038 0.0 - - - J - - - DnaB-like helicase C terminal domain
FMFMHKIL_00039 7.45e-111 - - - - - - - -
FMFMHKIL_00040 6.35e-229 - - - L - - - AAA domain
FMFMHKIL_00041 1.26e-214 - - - - - - - -
FMFMHKIL_00045 0.0 - - - M - - - Parallel beta-helix repeats
FMFMHKIL_00046 6.44e-177 - - - S - - - Pfam:DUF867
FMFMHKIL_00048 2.39e-26 - - - S - - - YopX protein
FMFMHKIL_00050 7.21e-165 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
FMFMHKIL_00051 8.69e-189 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
FMFMHKIL_00056 6.72e-94 - - - - - - - -
FMFMHKIL_00059 1.78e-56 - - - - - - - -
FMFMHKIL_00064 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
FMFMHKIL_00065 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
FMFMHKIL_00066 1.2e-122 - - - M - - - FR47-like protein
FMFMHKIL_00067 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
FMFMHKIL_00068 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
FMFMHKIL_00069 1.95e-109 yuaE - - S - - - DinB superfamily
FMFMHKIL_00070 8.58e-139 yuaD - - - - - - -
FMFMHKIL_00071 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
FMFMHKIL_00072 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FMFMHKIL_00073 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
FMFMHKIL_00074 5.83e-118 yuaB - - - - - - -
FMFMHKIL_00075 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
FMFMHKIL_00076 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
FMFMHKIL_00077 3.31e-52 yubF - - S - - - yiaA/B two helix domain
FMFMHKIL_00078 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FMFMHKIL_00079 0.0 yubD - - P - - - Major Facilitator Superfamily
FMFMHKIL_00080 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
FMFMHKIL_00082 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FMFMHKIL_00083 7.34e-254 yubA - - S - - - transporter activity
FMFMHKIL_00084 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
FMFMHKIL_00085 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
FMFMHKIL_00086 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
FMFMHKIL_00087 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
FMFMHKIL_00088 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
FMFMHKIL_00089 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
FMFMHKIL_00090 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_00091 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_00092 1.31e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_00093 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_00094 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
FMFMHKIL_00095 1.44e-47 - - - - - - - -
FMFMHKIL_00096 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
FMFMHKIL_00097 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
FMFMHKIL_00098 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
FMFMHKIL_00099 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
FMFMHKIL_00100 1.58e-50 - - - - - - - -
FMFMHKIL_00101 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
FMFMHKIL_00102 1.45e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
FMFMHKIL_00103 9.97e-94 yugN - - S - - - YugN-like family
FMFMHKIL_00105 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
FMFMHKIL_00106 5.34e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
FMFMHKIL_00107 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
FMFMHKIL_00108 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
FMFMHKIL_00109 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
FMFMHKIL_00110 3.14e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
FMFMHKIL_00111 6.74e-112 alaR - - K - - - Transcriptional regulator
FMFMHKIL_00112 9.89e-201 yugF - - I - - - Hydrolase
FMFMHKIL_00113 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
FMFMHKIL_00114 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
FMFMHKIL_00115 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00116 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
FMFMHKIL_00117 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
FMFMHKIL_00119 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
FMFMHKIL_00120 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
FMFMHKIL_00121 3.31e-98 yuxK - - S - - - protein conserved in bacteria
FMFMHKIL_00122 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
FMFMHKIL_00123 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
FMFMHKIL_00124 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
FMFMHKIL_00125 1.84e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
FMFMHKIL_00126 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00127 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FMFMHKIL_00128 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FMFMHKIL_00129 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
FMFMHKIL_00130 1.73e-22 - - - - - - - -
FMFMHKIL_00131 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FMFMHKIL_00132 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FMFMHKIL_00133 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FMFMHKIL_00134 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FMFMHKIL_00135 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FMFMHKIL_00136 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FMFMHKIL_00137 9.92e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
FMFMHKIL_00138 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
FMFMHKIL_00139 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_00140 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00142 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
FMFMHKIL_00143 6.29e-10 - - - S - - - DegQ (SacQ) family
FMFMHKIL_00144 8.73e-09 yuzC - - - - - - -
FMFMHKIL_00145 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
FMFMHKIL_00146 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FMFMHKIL_00147 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
FMFMHKIL_00148 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
FMFMHKIL_00149 1.63e-52 yueH - - S - - - YueH-like protein
FMFMHKIL_00150 2.05e-42 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
FMFMHKIL_00151 5.5e-244 yueF - - S - - - transporter activity
FMFMHKIL_00152 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
FMFMHKIL_00153 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
FMFMHKIL_00154 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
FMFMHKIL_00155 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_00156 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
FMFMHKIL_00157 0.0 yueB - - S - - - type VII secretion protein EsaA
FMFMHKIL_00158 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
FMFMHKIL_00159 3.93e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
FMFMHKIL_00160 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
FMFMHKIL_00161 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
FMFMHKIL_00162 8.49e-292 yukF - - QT - - - Transcriptional regulator
FMFMHKIL_00163 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
FMFMHKIL_00164 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
FMFMHKIL_00165 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
FMFMHKIL_00166 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_00167 4.47e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
FMFMHKIL_00168 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
FMFMHKIL_00169 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
FMFMHKIL_00170 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00171 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
FMFMHKIL_00172 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
FMFMHKIL_00173 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
FMFMHKIL_00174 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
FMFMHKIL_00175 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FMFMHKIL_00176 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
FMFMHKIL_00177 3.14e-149 yuiC - - S - - - protein conserved in bacteria
FMFMHKIL_00178 1.14e-45 yuiB - - S - - - Putative membrane protein
FMFMHKIL_00179 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
FMFMHKIL_00180 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
FMFMHKIL_00182 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FMFMHKIL_00183 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
FMFMHKIL_00184 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_00185 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
FMFMHKIL_00186 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FMFMHKIL_00187 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FMFMHKIL_00188 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
FMFMHKIL_00189 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
FMFMHKIL_00190 5.44e-74 yuzD - - S - - - protein conserved in bacteria
FMFMHKIL_00191 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
FMFMHKIL_00192 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
FMFMHKIL_00193 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FMFMHKIL_00194 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FMFMHKIL_00195 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
FMFMHKIL_00196 1.55e-253 yutH - - S - - - Spore coat protein
FMFMHKIL_00197 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
FMFMHKIL_00198 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FMFMHKIL_00199 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
FMFMHKIL_00200 3.2e-63 yutD - - S - - - protein conserved in bacteria
FMFMHKIL_00201 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FMFMHKIL_00202 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FMFMHKIL_00203 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
FMFMHKIL_00204 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
FMFMHKIL_00205 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
FMFMHKIL_00206 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FMFMHKIL_00207 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
FMFMHKIL_00208 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
FMFMHKIL_00209 1.07e-79 yunG - - - - - - -
FMFMHKIL_00210 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
FMFMHKIL_00211 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
FMFMHKIL_00212 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
FMFMHKIL_00213 1.24e-280 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
FMFMHKIL_00214 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
FMFMHKIL_00215 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
FMFMHKIL_00216 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
FMFMHKIL_00217 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
FMFMHKIL_00218 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
FMFMHKIL_00219 6.18e-143 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
FMFMHKIL_00220 3.56e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FMFMHKIL_00221 8.16e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
FMFMHKIL_00222 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
FMFMHKIL_00223 1.8e-215 bsn - - L - - - Ribonuclease
FMFMHKIL_00224 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_00225 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
FMFMHKIL_00226 5.54e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
FMFMHKIL_00227 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
FMFMHKIL_00228 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_00229 1.66e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
FMFMHKIL_00230 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
FMFMHKIL_00231 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
FMFMHKIL_00232 2.52e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
FMFMHKIL_00234 3.35e-56 - - - - - - - -
FMFMHKIL_00235 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
FMFMHKIL_00236 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
FMFMHKIL_00237 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FMFMHKIL_00238 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
FMFMHKIL_00239 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
FMFMHKIL_00240 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FMFMHKIL_00241 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
FMFMHKIL_00242 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
FMFMHKIL_00243 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMFMHKIL_00244 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
FMFMHKIL_00245 2e-73 yusE - - CO - - - Thioredoxin
FMFMHKIL_00246 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
FMFMHKIL_00247 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
FMFMHKIL_00248 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
FMFMHKIL_00249 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
FMFMHKIL_00250 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
FMFMHKIL_00251 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
FMFMHKIL_00252 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
FMFMHKIL_00253 1.11e-13 - - - S - - - YuzL-like protein
FMFMHKIL_00254 6.98e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
FMFMHKIL_00255 2.23e-54 - - - - - - - -
FMFMHKIL_00256 8.66e-70 yusN - - M - - - Coat F domain
FMFMHKIL_00257 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
FMFMHKIL_00258 0.0 yusP - - P - - - Major facilitator superfamily
FMFMHKIL_00259 2.93e-85 yusQ - - S - - - Tautomerase enzyme
FMFMHKIL_00260 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00261 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
FMFMHKIL_00262 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
FMFMHKIL_00263 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
FMFMHKIL_00264 2.86e-87 - - - S - - - YusW-like protein
FMFMHKIL_00265 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
FMFMHKIL_00266 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00267 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
FMFMHKIL_00268 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FMFMHKIL_00269 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_00270 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00271 3.06e-204 yuxN - - K - - - Transcriptional regulator
FMFMHKIL_00272 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FMFMHKIL_00273 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
FMFMHKIL_00274 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
FMFMHKIL_00275 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
FMFMHKIL_00276 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
FMFMHKIL_00277 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_00278 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00279 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
FMFMHKIL_00280 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
FMFMHKIL_00281 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
FMFMHKIL_00282 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
FMFMHKIL_00283 9.24e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_00284 4.56e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
FMFMHKIL_00285 2.47e-307 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
FMFMHKIL_00286 2.7e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_00287 1.21e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
FMFMHKIL_00288 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00289 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
FMFMHKIL_00290 0.0 yvrG - - T - - - Histidine kinase
FMFMHKIL_00291 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_00292 5.07e-32 - - - - - - - -
FMFMHKIL_00293 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
FMFMHKIL_00294 4.92e-26 - - - S - - - YvrJ protein family
FMFMHKIL_00295 1.86e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
FMFMHKIL_00296 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
FMFMHKIL_00297 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
FMFMHKIL_00298 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00299 1.47e-230 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
FMFMHKIL_00300 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
FMFMHKIL_00301 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_00302 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_00303 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMFMHKIL_00305 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
FMFMHKIL_00306 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
FMFMHKIL_00307 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
FMFMHKIL_00308 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
FMFMHKIL_00309 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
FMFMHKIL_00310 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
FMFMHKIL_00311 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
FMFMHKIL_00312 6.19e-201 yvgN - - S - - - reductase
FMFMHKIL_00313 7.97e-113 yvgO - - - - - - -
FMFMHKIL_00314 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
FMFMHKIL_00315 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
FMFMHKIL_00316 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FMFMHKIL_00317 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
FMFMHKIL_00319 2.34e-139 yvgT - - S - - - membrane
FMFMHKIL_00320 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
FMFMHKIL_00321 3.45e-137 bdbD - - O - - - Thioredoxin
FMFMHKIL_00322 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
FMFMHKIL_00323 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
FMFMHKIL_00324 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
FMFMHKIL_00325 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
FMFMHKIL_00326 1.4e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
FMFMHKIL_00327 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FMFMHKIL_00328 0.0 - - - S - - - Fusaric acid resistance protein-like
FMFMHKIL_00329 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
FMFMHKIL_00330 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
FMFMHKIL_00331 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
FMFMHKIL_00332 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00334 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FMFMHKIL_00335 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FMFMHKIL_00336 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
FMFMHKIL_00337 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
FMFMHKIL_00338 5.5e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
FMFMHKIL_00339 3.44e-48 yvzC - - K - - - transcriptional
FMFMHKIL_00340 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
FMFMHKIL_00341 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
FMFMHKIL_00342 3.85e-72 yvaP - - K - - - transcriptional
FMFMHKIL_00343 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_00344 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
FMFMHKIL_00345 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FMFMHKIL_00346 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
FMFMHKIL_00347 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FMFMHKIL_00348 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
FMFMHKIL_00349 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
FMFMHKIL_00350 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FMFMHKIL_00351 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
FMFMHKIL_00352 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FMFMHKIL_00353 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
FMFMHKIL_00354 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
FMFMHKIL_00355 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
FMFMHKIL_00356 1.61e-156 yvbI - - M - - - Membrane
FMFMHKIL_00357 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
FMFMHKIL_00358 6.87e-106 yvbK - - K - - - acetyltransferase
FMFMHKIL_00359 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FMFMHKIL_00360 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
FMFMHKIL_00361 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FMFMHKIL_00362 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
FMFMHKIL_00363 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FMFMHKIL_00364 9.84e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FMFMHKIL_00365 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMFMHKIL_00366 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
FMFMHKIL_00367 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_00369 5.49e-205 yvbU - - K - - - Transcriptional regulator
FMFMHKIL_00370 3.93e-198 yvbV - - EG - - - EamA-like transporter family
FMFMHKIL_00371 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_00372 1.22e-248 - - - S - - - Glycosyl hydrolase
FMFMHKIL_00373 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FMFMHKIL_00374 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
FMFMHKIL_00375 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FMFMHKIL_00376 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_00377 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00378 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
FMFMHKIL_00379 1.7e-208 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
FMFMHKIL_00380 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
FMFMHKIL_00381 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
FMFMHKIL_00382 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
FMFMHKIL_00383 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
FMFMHKIL_00384 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
FMFMHKIL_00385 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
FMFMHKIL_00386 1.68e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
FMFMHKIL_00387 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_00388 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
FMFMHKIL_00389 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
FMFMHKIL_00390 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
FMFMHKIL_00391 5.69e-44 yvfG - - S - - - YvfG protein
FMFMHKIL_00392 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
FMFMHKIL_00393 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
FMFMHKIL_00394 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
FMFMHKIL_00395 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FMFMHKIL_00396 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_00397 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_00398 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
FMFMHKIL_00399 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
FMFMHKIL_00400 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
FMFMHKIL_00401 5.9e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
FMFMHKIL_00402 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_00403 4.5e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
FMFMHKIL_00404 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
FMFMHKIL_00405 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
FMFMHKIL_00406 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
FMFMHKIL_00407 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
FMFMHKIL_00408 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
FMFMHKIL_00410 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
FMFMHKIL_00411 4.48e-96 - - - S - - - Protein of unknown function (DUF3237)
FMFMHKIL_00412 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
FMFMHKIL_00413 0.0 pbpE - - V - - - Beta-lactamase
FMFMHKIL_00414 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
FMFMHKIL_00415 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
FMFMHKIL_00416 0.0 ybeC - - E - - - amino acid
FMFMHKIL_00417 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
FMFMHKIL_00418 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
FMFMHKIL_00419 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
FMFMHKIL_00420 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
FMFMHKIL_00421 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
FMFMHKIL_00422 9.45e-234 - - - S - - - Patatin-like phospholipase
FMFMHKIL_00424 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FMFMHKIL_00425 2.91e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
FMFMHKIL_00426 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
FMFMHKIL_00427 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
FMFMHKIL_00428 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
FMFMHKIL_00429 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
FMFMHKIL_00430 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
FMFMHKIL_00431 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
FMFMHKIL_00432 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
FMFMHKIL_00433 1.54e-221 yvdE - - K - - - Transcriptional regulator
FMFMHKIL_00434 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
FMFMHKIL_00435 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
FMFMHKIL_00436 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
FMFMHKIL_00437 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
FMFMHKIL_00438 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMFMHKIL_00439 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
FMFMHKIL_00440 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00441 5.37e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
FMFMHKIL_00442 7.75e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_00443 1.37e-45 - - - - - - - -
FMFMHKIL_00444 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
FMFMHKIL_00445 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
FMFMHKIL_00446 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
FMFMHKIL_00447 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
FMFMHKIL_00448 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
FMFMHKIL_00449 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FMFMHKIL_00450 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FMFMHKIL_00451 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
FMFMHKIL_00452 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
FMFMHKIL_00453 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
FMFMHKIL_00455 0.0 - - - - - - - -
FMFMHKIL_00456 6.36e-172 - - - - - - - -
FMFMHKIL_00457 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
FMFMHKIL_00458 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FMFMHKIL_00459 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FMFMHKIL_00460 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FMFMHKIL_00461 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
FMFMHKIL_00462 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FMFMHKIL_00463 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FMFMHKIL_00464 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FMFMHKIL_00465 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
FMFMHKIL_00466 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
FMFMHKIL_00467 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
FMFMHKIL_00468 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
FMFMHKIL_00469 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
FMFMHKIL_00470 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FMFMHKIL_00471 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FMFMHKIL_00472 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
FMFMHKIL_00473 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FMFMHKIL_00474 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
FMFMHKIL_00475 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
FMFMHKIL_00476 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_00477 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
FMFMHKIL_00478 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
FMFMHKIL_00479 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_00480 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
FMFMHKIL_00481 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
FMFMHKIL_00482 2.49e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
FMFMHKIL_00483 1.85e-217 yvlB - - S - - - Putative adhesin
FMFMHKIL_00484 3.3e-64 yvlA - - - - - - -
FMFMHKIL_00485 2.25e-45 yvkN - - - - - - -
FMFMHKIL_00486 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FMFMHKIL_00487 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FMFMHKIL_00488 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FMFMHKIL_00489 2.54e-42 csbA - - S - - - protein conserved in bacteria
FMFMHKIL_00490 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
FMFMHKIL_00491 2.36e-130 yvkB - - K - - - Transcriptional regulator
FMFMHKIL_00492 5.24e-296 yvkA - - P - - - -transporter
FMFMHKIL_00493 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FMFMHKIL_00494 1.38e-73 swrA - - S - - - Swarming motility protein
FMFMHKIL_00495 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
FMFMHKIL_00496 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
FMFMHKIL_00497 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
FMFMHKIL_00498 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
FMFMHKIL_00499 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
FMFMHKIL_00500 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FMFMHKIL_00501 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FMFMHKIL_00502 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FMFMHKIL_00503 9.14e-88 - - - - - - - -
FMFMHKIL_00504 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
FMFMHKIL_00505 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
FMFMHKIL_00506 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FMFMHKIL_00507 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
FMFMHKIL_00508 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FMFMHKIL_00509 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FMFMHKIL_00510 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FMFMHKIL_00511 6.92e-92 yviE - - - - - - -
FMFMHKIL_00512 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
FMFMHKIL_00513 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
FMFMHKIL_00514 7.06e-102 yvyG - - NOU - - - FlgN protein
FMFMHKIL_00515 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
FMFMHKIL_00516 1.83e-96 yvyF - - S - - - flagellar protein
FMFMHKIL_00517 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
FMFMHKIL_00518 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
FMFMHKIL_00519 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FMFMHKIL_00520 1.77e-198 degV - - S - - - protein conserved in bacteria
FMFMHKIL_00521 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_00522 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
FMFMHKIL_00523 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
FMFMHKIL_00524 3.81e-223 yvhJ - - K - - - Transcriptional regulator
FMFMHKIL_00525 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
FMFMHKIL_00526 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
FMFMHKIL_00527 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
FMFMHKIL_00528 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
FMFMHKIL_00529 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
FMFMHKIL_00530 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FMFMHKIL_00531 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
FMFMHKIL_00532 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_00533 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FMFMHKIL_00534 7e-108 - - - M - - - Glycosyltransferase like family 2
FMFMHKIL_00535 2.25e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
FMFMHKIL_00536 0.0 lytB - - D - - - Stage II sporulation protein
FMFMHKIL_00537 9.07e-16 - - - - - - - -
FMFMHKIL_00538 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
FMFMHKIL_00539 7.71e-277 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FMFMHKIL_00540 2.94e-103 - - - M - - - Glycosyltransferase like family 2
FMFMHKIL_00541 3.05e-119 - - - M - - - Glycosyl transferases group 1
FMFMHKIL_00543 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
FMFMHKIL_00544 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
FMFMHKIL_00545 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
FMFMHKIL_00546 7.8e-102 - - - - - - - -
FMFMHKIL_00547 5.37e-68 - - - - - - - -
FMFMHKIL_00548 7.58e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FMFMHKIL_00549 4.14e-106 - - - M - - - Glycosyltransferase like family 2
FMFMHKIL_00550 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FMFMHKIL_00551 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
FMFMHKIL_00552 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FMFMHKIL_00553 1.01e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FMFMHKIL_00554 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
FMFMHKIL_00555 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
FMFMHKIL_00556 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FMFMHKIL_00557 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FMFMHKIL_00558 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FMFMHKIL_00559 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FMFMHKIL_00560 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
FMFMHKIL_00561 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
FMFMHKIL_00562 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
FMFMHKIL_00563 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMFMHKIL_00564 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
FMFMHKIL_00565 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
FMFMHKIL_00566 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FMFMHKIL_00567 2.29e-29 ywtC - - - - - - -
FMFMHKIL_00568 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
FMFMHKIL_00569 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
FMFMHKIL_00570 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
FMFMHKIL_00571 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
FMFMHKIL_00572 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FMFMHKIL_00573 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
FMFMHKIL_00574 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
FMFMHKIL_00575 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FMFMHKIL_00576 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
FMFMHKIL_00577 1.62e-118 batE - - T - - - Sh3 type 3 domain protein
FMFMHKIL_00578 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
FMFMHKIL_00579 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
FMFMHKIL_00580 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
FMFMHKIL_00581 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
FMFMHKIL_00582 3.36e-218 alsR - - K - - - LysR substrate binding domain
FMFMHKIL_00583 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FMFMHKIL_00584 2.5e-161 ywrJ - - - - - - -
FMFMHKIL_00585 1.37e-194 cotB - - - ko:K06325 - ko00000 -
FMFMHKIL_00586 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
FMFMHKIL_00587 2.17e-16 - - - - - - - -
FMFMHKIL_00588 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FMFMHKIL_00589 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
FMFMHKIL_00590 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
FMFMHKIL_00591 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
FMFMHKIL_00592 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
FMFMHKIL_00593 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
FMFMHKIL_00595 6.11e-129 ywqN - - S - - - NAD(P)H-dependent
FMFMHKIL_00596 3.33e-209 - - - K - - - Transcriptional regulator
FMFMHKIL_00597 8.51e-155 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
FMFMHKIL_00598 1.13e-126 - - - - - - - -
FMFMHKIL_00600 2.2e-66 - - - - - - - -
FMFMHKIL_00601 1.29e-97 - - - - - - - -
FMFMHKIL_00602 1.95e-297 ywqJ - - S - - - Pre-toxin TG
FMFMHKIL_00603 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
FMFMHKIL_00605 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
FMFMHKIL_00606 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FMFMHKIL_00607 1.18e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
FMFMHKIL_00608 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
FMFMHKIL_00609 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
FMFMHKIL_00610 3.6e-25 - - - - - - - -
FMFMHKIL_00611 0.0 ywqB - - S - - - SWIM zinc finger
FMFMHKIL_00612 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
FMFMHKIL_00613 1.45e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
FMFMHKIL_00614 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
FMFMHKIL_00615 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
FMFMHKIL_00616 3.56e-86 ywpG - - - - - - -
FMFMHKIL_00617 3.59e-88 ywpF - - S - - - YwpF-like protein
FMFMHKIL_00618 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
FMFMHKIL_00619 2.51e-18 - - - M - - - cell wall anchor domain
FMFMHKIL_00620 1.28e-66 ywpD - - T - - - Histidine kinase
FMFMHKIL_00621 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FMFMHKIL_00622 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FMFMHKIL_00623 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
FMFMHKIL_00624 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
FMFMHKIL_00625 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
FMFMHKIL_00626 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
FMFMHKIL_00627 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
FMFMHKIL_00628 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
FMFMHKIL_00629 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_00630 7.65e-308 ywoF - - P - - - Right handed beta helix region
FMFMHKIL_00631 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
FMFMHKIL_00632 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
FMFMHKIL_00633 1.04e-133 yjgF - - Q - - - Isochorismatase family
FMFMHKIL_00634 5.04e-101 - - - - - - - -
FMFMHKIL_00635 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
FMFMHKIL_00636 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
FMFMHKIL_00637 3.48e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
FMFMHKIL_00638 6.63e-95 ywnJ - - S - - - VanZ like family
FMFMHKIL_00639 1.3e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
FMFMHKIL_00640 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
FMFMHKIL_00641 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
FMFMHKIL_00642 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
FMFMHKIL_00643 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMFMHKIL_00644 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
FMFMHKIL_00645 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
FMFMHKIL_00646 1.02e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
FMFMHKIL_00647 4.58e-85 ywnA - - K - - - Transcriptional regulator
FMFMHKIL_00648 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
FMFMHKIL_00649 7.55e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
FMFMHKIL_00650 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
FMFMHKIL_00652 1.84e-20 csbD - - K - - - CsbD-like
FMFMHKIL_00653 1.12e-109 ywmF - - S - - - Peptidase M50
FMFMHKIL_00654 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
FMFMHKIL_00655 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FMFMHKIL_00656 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FMFMHKIL_00658 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
FMFMHKIL_00659 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
FMFMHKIL_00660 9.77e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
FMFMHKIL_00661 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FMFMHKIL_00662 2.68e-171 ywmB - - S - - - TATA-box binding
FMFMHKIL_00663 4.54e-45 ywzB - - S - - - membrane
FMFMHKIL_00664 4.84e-112 ywmA - - - - - - -
FMFMHKIL_00665 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
FMFMHKIL_00666 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FMFMHKIL_00667 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FMFMHKIL_00668 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FMFMHKIL_00669 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FMFMHKIL_00670 1.24e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FMFMHKIL_00671 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FMFMHKIL_00672 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
FMFMHKIL_00673 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
FMFMHKIL_00674 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FMFMHKIL_00675 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FMFMHKIL_00676 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
FMFMHKIL_00677 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
FMFMHKIL_00678 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FMFMHKIL_00679 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
FMFMHKIL_00680 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FMFMHKIL_00681 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
FMFMHKIL_00682 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
FMFMHKIL_00683 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
FMFMHKIL_00685 7.78e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FMFMHKIL_00686 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FMFMHKIL_00687 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_00688 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
FMFMHKIL_00689 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
FMFMHKIL_00690 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
FMFMHKIL_00691 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
FMFMHKIL_00692 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
FMFMHKIL_00693 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FMFMHKIL_00694 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
FMFMHKIL_00695 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FMFMHKIL_00696 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FMFMHKIL_00697 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
FMFMHKIL_00698 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
FMFMHKIL_00699 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
FMFMHKIL_00700 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FMFMHKIL_00701 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FMFMHKIL_00702 1.65e-266 acdA - - I - - - acyl-CoA dehydrogenase
FMFMHKIL_00703 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
FMFMHKIL_00704 9.57e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
FMFMHKIL_00705 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
FMFMHKIL_00706 1.32e-57 ywjC - - - - - - -
FMFMHKIL_00707 7.5e-122 ywjB - - H - - - RibD C-terminal domain
FMFMHKIL_00708 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
FMFMHKIL_00709 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMFMHKIL_00710 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
FMFMHKIL_00711 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
FMFMHKIL_00712 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
FMFMHKIL_00713 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FMFMHKIL_00714 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
FMFMHKIL_00715 1.51e-178 ywiC - - S - - - YwiC-like protein
FMFMHKIL_00716 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
FMFMHKIL_00717 1.4e-272 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
FMFMHKIL_00718 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
FMFMHKIL_00719 4.64e-96 ywiB - - S - - - protein conserved in bacteria
FMFMHKIL_00720 3.71e-12 - - - S - - - Bacteriocin subtilosin A
FMFMHKIL_00721 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
FMFMHKIL_00723 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
FMFMHKIL_00724 1.46e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
FMFMHKIL_00725 4.88e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
FMFMHKIL_00726 0.0 - - - L - - - Peptidase, M16
FMFMHKIL_00728 0.0 ywhL - - CO - - - amine dehydrogenase activity
FMFMHKIL_00729 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
FMFMHKIL_00730 6.56e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
FMFMHKIL_00734 1.3e-10 - - - - - - - -
FMFMHKIL_00737 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
FMFMHKIL_00739 1.42e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
FMFMHKIL_00740 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FMFMHKIL_00741 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FMFMHKIL_00742 5.51e-123 ywhD - - S - - - YwhD family
FMFMHKIL_00743 3.29e-154 ywhC - - S - - - Peptidase family M50
FMFMHKIL_00744 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
FMFMHKIL_00745 1.45e-93 ywhA - - K - - - Transcriptional regulator
FMFMHKIL_00746 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FMFMHKIL_00748 2.66e-263 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
FMFMHKIL_00749 6.12e-20 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
FMFMHKIL_00750 1.28e-102 yffB - - K - - - Transcriptional regulator
FMFMHKIL_00751 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
FMFMHKIL_00752 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
FMFMHKIL_00753 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
FMFMHKIL_00754 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
FMFMHKIL_00755 3.69e-201 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
FMFMHKIL_00756 2.51e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
FMFMHKIL_00757 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_00758 6.8e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
FMFMHKIL_00759 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
FMFMHKIL_00760 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_00761 1.74e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
FMFMHKIL_00762 1.85e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
FMFMHKIL_00763 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
FMFMHKIL_00764 1.56e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_00765 7.2e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
FMFMHKIL_00766 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
FMFMHKIL_00767 3.12e-274 ywfA - - EGP - - - -transporter
FMFMHKIL_00768 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FMFMHKIL_00769 0.0 rocB - - E - - - arginine degradation protein
FMFMHKIL_00770 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
FMFMHKIL_00771 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
FMFMHKIL_00772 1.1e-102 - - - - - - - -
FMFMHKIL_00773 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
FMFMHKIL_00774 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
FMFMHKIL_00775 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FMFMHKIL_00776 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FMFMHKIL_00777 2.54e-243 spsG - - M - - - Spore Coat
FMFMHKIL_00778 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
FMFMHKIL_00779 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
FMFMHKIL_00780 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
FMFMHKIL_00781 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
FMFMHKIL_00782 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
FMFMHKIL_00783 2.32e-186 spsA - - M - - - Spore Coat
FMFMHKIL_00784 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
FMFMHKIL_00785 1.59e-78 ywdK - - S - - - small membrane protein
FMFMHKIL_00786 1.86e-303 ywdJ - - F - - - Xanthine uracil
FMFMHKIL_00787 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
FMFMHKIL_00788 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FMFMHKIL_00789 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FMFMHKIL_00790 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
FMFMHKIL_00792 8.74e-146 ywdD - - - - - - -
FMFMHKIL_00793 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
FMFMHKIL_00794 7.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
FMFMHKIL_00795 6.19e-39 ywdA - - - - - - -
FMFMHKIL_00796 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
FMFMHKIL_00797 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_00798 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
FMFMHKIL_00799 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
FMFMHKIL_00801 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_00802 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_00803 5.44e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
FMFMHKIL_00804 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
FMFMHKIL_00805 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
FMFMHKIL_00806 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
FMFMHKIL_00807 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
FMFMHKIL_00808 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FMFMHKIL_00809 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
FMFMHKIL_00810 5.11e-49 ydaS - - S - - - membrane
FMFMHKIL_00811 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
FMFMHKIL_00812 1.79e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FMFMHKIL_00813 3.33e-77 gtcA - - S - - - GtrA-like protein
FMFMHKIL_00814 7.35e-143 ywcC - - K - - - transcriptional regulator
FMFMHKIL_00816 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
FMFMHKIL_00817 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FMFMHKIL_00818 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
FMFMHKIL_00819 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
FMFMHKIL_00820 1.98e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
FMFMHKIL_00821 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
FMFMHKIL_00822 1e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FMFMHKIL_00823 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FMFMHKIL_00824 2.7e-203 ywbI - - K - - - Transcriptional regulator
FMFMHKIL_00825 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
FMFMHKIL_00826 1.21e-143 ywbG - - M - - - effector of murein hydrolase
FMFMHKIL_00827 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
FMFMHKIL_00828 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
FMFMHKIL_00829 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
FMFMHKIL_00830 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
FMFMHKIL_00831 1.59e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FMFMHKIL_00832 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_00833 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_00834 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
FMFMHKIL_00835 4.41e-215 gspA - - M - - - General stress
FMFMHKIL_00836 1.66e-156 ywaF - - S - - - Integral membrane protein
FMFMHKIL_00837 4.18e-113 ywaE - - K - - - Transcriptional regulator
FMFMHKIL_00838 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FMFMHKIL_00839 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
FMFMHKIL_00840 5.37e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
FMFMHKIL_00841 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
FMFMHKIL_00842 2.79e-165 - - - EGP - - - Permeases of the major facilitator superfamily
FMFMHKIL_00843 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
FMFMHKIL_00844 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
FMFMHKIL_00845 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_00846 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
FMFMHKIL_00847 1.61e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_00848 8.26e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FMFMHKIL_00849 8e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00850 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
FMFMHKIL_00851 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FMFMHKIL_00852 1.18e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_00853 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FMFMHKIL_00854 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
FMFMHKIL_00855 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
FMFMHKIL_00856 8.94e-28 yxzF - - - - - - -
FMFMHKIL_00857 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
FMFMHKIL_00858 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
FMFMHKIL_00859 3.23e-270 yxlH - - EGP - - - Major Facilitator Superfamily
FMFMHKIL_00860 8.58e-174 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FMFMHKIL_00861 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00862 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
FMFMHKIL_00863 1.75e-43 - - - - - - - -
FMFMHKIL_00864 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
FMFMHKIL_00865 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_00866 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
FMFMHKIL_00867 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FMFMHKIL_00868 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
FMFMHKIL_00869 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
FMFMHKIL_00870 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
FMFMHKIL_00871 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
FMFMHKIL_00872 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
FMFMHKIL_00873 0.0 - - - O - - - Peptidase family M48
FMFMHKIL_00875 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
FMFMHKIL_00876 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_00877 3.89e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
FMFMHKIL_00878 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FMFMHKIL_00879 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
FMFMHKIL_00880 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
FMFMHKIL_00881 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
FMFMHKIL_00882 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
FMFMHKIL_00883 4.59e-257 - - - T - - - Signal transduction histidine kinase
FMFMHKIL_00884 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
FMFMHKIL_00885 2.6e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
FMFMHKIL_00888 1.43e-111 yxjI - - S - - - LURP-one-related
FMFMHKIL_00889 1.28e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
FMFMHKIL_00890 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
FMFMHKIL_00891 6.8e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
FMFMHKIL_00892 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FMFMHKIL_00893 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FMFMHKIL_00894 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
FMFMHKIL_00895 8.81e-204 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
FMFMHKIL_00896 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FMFMHKIL_00897 2.83e-131 - - - T - - - Domain of unknown function (DUF4163)
FMFMHKIL_00898 5.39e-62 yxiS - - - - - - -
FMFMHKIL_00899 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
FMFMHKIL_00900 3.31e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
FMFMHKIL_00901 1.46e-182 bglS - - M - - - licheninase activity
FMFMHKIL_00902 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
FMFMHKIL_00903 4.37e-142 - - - - - - - -
FMFMHKIL_00904 1.09e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
FMFMHKIL_00905 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
FMFMHKIL_00906 2.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
FMFMHKIL_00907 1.86e-70 - - - K - - - Transcriptional regulator PadR-like family
FMFMHKIL_00908 2.16e-53 - - - S - - - Protein of unknown function (DUF2812)
FMFMHKIL_00909 2.34e-21 - - - S - - - YxiJ-like protein
FMFMHKIL_00910 0.0 wapA - - M - - - COG3209 Rhs family protein
FMFMHKIL_00911 8.44e-210 yxxF - - EG - - - EamA-like transporter family
FMFMHKIL_00912 2.2e-28 - - - - - - - -
FMFMHKIL_00913 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
FMFMHKIL_00915 1.24e-113 - - - - - - - -
FMFMHKIL_00916 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
FMFMHKIL_00917 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
FMFMHKIL_00918 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FMFMHKIL_00919 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_00920 1.33e-62 - - - - - - - -
FMFMHKIL_00921 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
FMFMHKIL_00922 6.09e-292 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
FMFMHKIL_00924 2.81e-26 - - - S - - - protein conserved in bacteria
FMFMHKIL_00926 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
FMFMHKIL_00927 4.47e-51 yxiC - - S - - - Family of unknown function (DUF5344)
FMFMHKIL_00928 2.18e-36 - - - S - - - Domain of unknown function (DUF5082)
FMFMHKIL_00929 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
FMFMHKIL_00930 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
FMFMHKIL_00931 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
FMFMHKIL_00932 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FMFMHKIL_00933 2.61e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
FMFMHKIL_00934 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
FMFMHKIL_00935 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FMFMHKIL_00936 6.66e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
FMFMHKIL_00937 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FMFMHKIL_00938 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FMFMHKIL_00939 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FMFMHKIL_00940 1.76e-195 - - - S - - - Domain of Unknown Function (DUF1206)
FMFMHKIL_00941 7.72e-256 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
FMFMHKIL_00942 1.39e-312 yxeQ - - S - - - MmgE/PrpD family
FMFMHKIL_00943 2.65e-268 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
FMFMHKIL_00944 2.78e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00945 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
FMFMHKIL_00946 5.02e-185 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
FMFMHKIL_00947 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_00948 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_00949 9.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
FMFMHKIL_00950 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
FMFMHKIL_00953 7.32e-42 yxeE - - - - - - -
FMFMHKIL_00954 7.57e-28 yxeD - - - - - - -
FMFMHKIL_00955 6.79e-91 - - - - - - - -
FMFMHKIL_00956 4.99e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMFMHKIL_00957 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
FMFMHKIL_00958 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
FMFMHKIL_00959 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_00960 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_00961 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_00962 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
FMFMHKIL_00963 1.96e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
FMFMHKIL_00964 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
FMFMHKIL_00965 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
FMFMHKIL_00966 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
FMFMHKIL_00967 1.74e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
FMFMHKIL_00968 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
FMFMHKIL_00969 6.09e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
FMFMHKIL_00970 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
FMFMHKIL_00971 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FMFMHKIL_00972 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
FMFMHKIL_00973 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
FMFMHKIL_00975 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
FMFMHKIL_00976 2.4e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMFMHKIL_00977 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
FMFMHKIL_00979 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_00980 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
FMFMHKIL_00981 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FMFMHKIL_00982 2.09e-16 yxaI - - S - - - membrane protein domain
FMFMHKIL_00983 1.73e-135 yxaL - - S - - - PQQ-like domain
FMFMHKIL_00984 1.96e-83 - - - S - - - Family of unknown function (DUF5391)
FMFMHKIL_00985 4.03e-99 yxaI - - S - - - membrane protein domain
FMFMHKIL_00986 6.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
FMFMHKIL_00987 1e-248 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
FMFMHKIL_00988 7.9e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
FMFMHKIL_00989 5.01e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_00990 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_00991 5.96e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
FMFMHKIL_00992 7.33e-152 yxaC - - M - - - effector of murein hydrolase
FMFMHKIL_00993 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
FMFMHKIL_00994 1.64e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
FMFMHKIL_00995 2.56e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
FMFMHKIL_00996 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
FMFMHKIL_00997 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
FMFMHKIL_00998 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FMFMHKIL_00999 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
FMFMHKIL_01000 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
FMFMHKIL_01001 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
FMFMHKIL_01002 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FMFMHKIL_01003 8.38e-44 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_01004 1.23e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_01005 2.4e-23 - - - - - - - -
FMFMHKIL_01006 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
FMFMHKIL_01007 0.0 - - - L - - - AAA domain
FMFMHKIL_01008 6.93e-310 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
FMFMHKIL_01009 3.64e-56 - - - S - - - MazG-like family
FMFMHKIL_01010 1.09e-140 - - - S - - - Caspase domain
FMFMHKIL_01011 1.23e-134 - - - L - - - reverse transcriptase
FMFMHKIL_01013 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FMFMHKIL_01015 8.12e-90 - - - - - - - -
FMFMHKIL_01016 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FMFMHKIL_01018 2.24e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
FMFMHKIL_01019 1.01e-271 yycP - - - - - - -
FMFMHKIL_01020 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FMFMHKIL_01021 5.25e-111 yycN - - K - - - Acetyltransferase
FMFMHKIL_01022 1.06e-239 - - - S - - - aspartate phosphatase
FMFMHKIL_01024 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
FMFMHKIL_01025 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FMFMHKIL_01026 8.29e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
FMFMHKIL_01027 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
FMFMHKIL_01028 5.58e-216 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
FMFMHKIL_01029 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
FMFMHKIL_01030 9.34e-98 - - - S - - - Peptidase propeptide and YPEB domain
FMFMHKIL_01031 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
FMFMHKIL_01032 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FMFMHKIL_01033 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
FMFMHKIL_01034 2.83e-199 yycI - - S - - - protein conserved in bacteria
FMFMHKIL_01035 0.0 yycH - - S - - - protein conserved in bacteria
FMFMHKIL_01036 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_01037 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_01042 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FMFMHKIL_01043 3.85e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_01044 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
FMFMHKIL_01045 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
FMFMHKIL_01047 1.89e-22 yycC - - K - - - YycC-like protein
FMFMHKIL_01048 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
FMFMHKIL_01049 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMFMHKIL_01050 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
FMFMHKIL_01051 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
FMFMHKIL_01052 8.66e-204 yybS - - S - - - membrane
FMFMHKIL_01054 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
FMFMHKIL_01055 1.3e-87 yybR - - K - - - Transcriptional regulator
FMFMHKIL_01056 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
FMFMHKIL_01057 3.67e-80 - - - - - - - -
FMFMHKIL_01059 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_01060 1.46e-140 - - - K - - - TipAS antibiotic-recognition domain
FMFMHKIL_01061 2.05e-183 - - - - - - - -
FMFMHKIL_01062 2.49e-87 - - - S - - - SnoaL-like domain
FMFMHKIL_01063 5.67e-162 yybG - - S - - - Pentapeptide repeat-containing protein
FMFMHKIL_01064 8.32e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_01065 1.31e-210 yybE - - K - - - Transcriptional regulator
FMFMHKIL_01066 1.26e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
FMFMHKIL_01067 1.94e-94 yybC - - - - - - -
FMFMHKIL_01068 2.52e-163 - - - S - - - Metallo-beta-lactamase superfamily
FMFMHKIL_01069 4.54e-100 yybA - - K - - - transcriptional
FMFMHKIL_01070 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
FMFMHKIL_01071 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
FMFMHKIL_01072 1.84e-117 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
FMFMHKIL_01073 1.23e-84 - - - S - - - YjbR
FMFMHKIL_01074 7.09e-136 yyaP - - H - - - RibD C-terminal domain
FMFMHKIL_01075 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_01076 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
FMFMHKIL_01077 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
FMFMHKIL_01078 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
FMFMHKIL_01079 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
FMFMHKIL_01080 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_01081 6.85e-227 ccpB - - K - - - Transcriptional regulator
FMFMHKIL_01082 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
FMFMHKIL_01083 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FMFMHKIL_01084 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FMFMHKIL_01085 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
FMFMHKIL_01086 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FMFMHKIL_01087 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FMFMHKIL_01088 7.41e-45 yyzM - - S - - - protein conserved in bacteria
FMFMHKIL_01089 5.34e-227 yyaD - - S - - - Membrane
FMFMHKIL_01090 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
FMFMHKIL_01091 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
FMFMHKIL_01092 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
FMFMHKIL_01093 9.26e-98 - - - S - - - Bacterial PH domain
FMFMHKIL_01094 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
FMFMHKIL_01095 5.86e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
FMFMHKIL_01096 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FMFMHKIL_01097 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FMFMHKIL_01098 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
FMFMHKIL_01099 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FMFMHKIL_01100 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FMFMHKIL_01101 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FMFMHKIL_01102 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FMFMHKIL_01103 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
FMFMHKIL_01104 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FMFMHKIL_01105 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
FMFMHKIL_01106 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FMFMHKIL_01107 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FMFMHKIL_01108 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_01109 9.13e-202 yitS - - S - - - protein conserved in bacteria
FMFMHKIL_01110 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
FMFMHKIL_01111 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
FMFMHKIL_01112 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
FMFMHKIL_01113 1.92e-08 - - - - - - - -
FMFMHKIL_01114 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
FMFMHKIL_01115 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
FMFMHKIL_01116 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
FMFMHKIL_01117 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
FMFMHKIL_01118 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
FMFMHKIL_01119 2.04e-91 yitZ - - G - - - Major Facilitator Superfamily
FMFMHKIL_01120 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FMFMHKIL_01121 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FMFMHKIL_01122 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
FMFMHKIL_01123 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
FMFMHKIL_01124 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
FMFMHKIL_01125 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
FMFMHKIL_01126 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FMFMHKIL_01127 2.51e-39 yjzC - - S - - - YjzC-like protein
FMFMHKIL_01128 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
FMFMHKIL_01129 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
FMFMHKIL_01130 5.41e-134 yjaV - - - - - - -
FMFMHKIL_01131 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
FMFMHKIL_01132 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
FMFMHKIL_01133 2.67e-38 yjzB - - - - - - -
FMFMHKIL_01134 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FMFMHKIL_01135 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FMFMHKIL_01136 9.48e-193 yjaZ - - O - - - Zn-dependent protease
FMFMHKIL_01137 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_01138 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_01139 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
FMFMHKIL_01140 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_01141 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_01142 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
FMFMHKIL_01143 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
FMFMHKIL_01144 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
FMFMHKIL_01145 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_01146 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_01147 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_01148 3.12e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_01149 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
FMFMHKIL_01150 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_01151 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FMFMHKIL_01152 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
FMFMHKIL_01153 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FMFMHKIL_01154 4.38e-282 coiA - - S ko:K06198 - ko00000 Competence protein
FMFMHKIL_01155 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
FMFMHKIL_01156 2.68e-28 - - - - - - - -
FMFMHKIL_01158 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
FMFMHKIL_01159 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
FMFMHKIL_01160 7.22e-129 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FMFMHKIL_01161 4.94e-128 yjbK - - S - - - protein conserved in bacteria
FMFMHKIL_01162 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
FMFMHKIL_01163 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
FMFMHKIL_01164 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FMFMHKIL_01165 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
FMFMHKIL_01166 6.5e-162 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
FMFMHKIL_01167 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FMFMHKIL_01168 1.11e-174 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FMFMHKIL_01169 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
FMFMHKIL_01170 1.42e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
FMFMHKIL_01171 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
FMFMHKIL_01172 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
FMFMHKIL_01173 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FMFMHKIL_01174 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
FMFMHKIL_01175 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
FMFMHKIL_01176 3.11e-98 yjbX - - S - - - Spore coat protein
FMFMHKIL_01177 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
FMFMHKIL_01178 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
FMFMHKIL_01179 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
FMFMHKIL_01180 9.3e-32 cotW - - - ko:K06341 - ko00000 -
FMFMHKIL_01181 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
FMFMHKIL_01182 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
FMFMHKIL_01185 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
FMFMHKIL_01186 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
FMFMHKIL_01187 6.31e-51 - - - - - - - -
FMFMHKIL_01188 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_01189 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
FMFMHKIL_01190 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
FMFMHKIL_01191 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FMFMHKIL_01192 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FMFMHKIL_01193 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
FMFMHKIL_01194 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
FMFMHKIL_01197 1.33e-50 - - - - - - - -
FMFMHKIL_01199 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
FMFMHKIL_01202 1.42e-09 - - - S - - - YolD-like protein
FMFMHKIL_01203 1.92e-47 - - - - - - - -
FMFMHKIL_01204 3.94e-26 - - - - - - - -
FMFMHKIL_01205 2.49e-07 - - - - - - - -
FMFMHKIL_01206 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
FMFMHKIL_01207 9.79e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_01208 0.000759 - - - - - - - -
FMFMHKIL_01209 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
FMFMHKIL_01210 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_01211 1.4e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FMFMHKIL_01212 3.08e-74 yjdF3 - - S - - - Protein of unknown function (DUF2992)
FMFMHKIL_01213 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
FMFMHKIL_01215 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FMFMHKIL_01216 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
FMFMHKIL_01217 4.66e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
FMFMHKIL_01218 1.52e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FMFMHKIL_01220 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
FMFMHKIL_01221 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
FMFMHKIL_01222 1.95e-30 yjfB - - S - - - Putative motility protein
FMFMHKIL_01223 1.42e-213 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
FMFMHKIL_01224 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
FMFMHKIL_01225 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
FMFMHKIL_01226 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
FMFMHKIL_01227 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
FMFMHKIL_01229 3.17e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
FMFMHKIL_01231 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
FMFMHKIL_01232 5.89e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FMFMHKIL_01233 1.11e-41 - - - - - - - -
FMFMHKIL_01234 1.13e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
FMFMHKIL_01235 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
FMFMHKIL_01236 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
FMFMHKIL_01237 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
FMFMHKIL_01238 1.42e-117 yjlB - - S - - - Cupin domain
FMFMHKIL_01239 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
FMFMHKIL_01240 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
FMFMHKIL_01241 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
FMFMHKIL_01242 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
FMFMHKIL_01243 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
FMFMHKIL_01244 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
FMFMHKIL_01245 3.92e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
FMFMHKIL_01246 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_01247 9.24e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
FMFMHKIL_01248 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
FMFMHKIL_01249 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
FMFMHKIL_01250 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
FMFMHKIL_01251 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
FMFMHKIL_01252 2.71e-103 yjoA - - S - - - DinB family
FMFMHKIL_01253 1.67e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
FMFMHKIL_01254 3.5e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
FMFMHKIL_01256 1.79e-55 - - - S - - - YCII-related domain
FMFMHKIL_01257 5.12e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
FMFMHKIL_01258 1.35e-80 yjqA - - S - - - Bacterial PH domain
FMFMHKIL_01259 3.73e-137 yjqB - - S - - - Pfam:DUF867
FMFMHKIL_01260 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
FMFMHKIL_01261 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
FMFMHKIL_01262 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
FMFMHKIL_01264 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
FMFMHKIL_01265 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
FMFMHKIL_01269 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
FMFMHKIL_01270 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
FMFMHKIL_01271 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
FMFMHKIL_01272 0.0 yqbA - - S - - - portal protein
FMFMHKIL_01273 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
FMFMHKIL_01274 3.91e-217 xkdG - - S - - - Phage capsid family
FMFMHKIL_01275 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
FMFMHKIL_01276 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
FMFMHKIL_01277 8.3e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
FMFMHKIL_01278 2.87e-101 xkdJ - - - - - - -
FMFMHKIL_01279 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
FMFMHKIL_01280 6.01e-99 xkdM - - S - - - Phage tail tube protein
FMFMHKIL_01281 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
FMFMHKIL_01282 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
FMFMHKIL_01284 5.36e-203 ybaS - - S - - - Na -dependent transporter
FMFMHKIL_01285 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
FMFMHKIL_01286 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_01287 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_01288 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
FMFMHKIL_01289 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
FMFMHKIL_01290 8.14e-303 ybbC - - S - - - protein conserved in bacteria
FMFMHKIL_01291 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
FMFMHKIL_01292 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
FMFMHKIL_01293 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_01294 3.01e-191 ybbH - - K - - - transcriptional
FMFMHKIL_01295 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FMFMHKIL_01296 1.81e-113 ybbJ - - J - - - acetyltransferase
FMFMHKIL_01297 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
FMFMHKIL_01303 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_01304 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
FMFMHKIL_01305 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FMFMHKIL_01306 3.41e-291 ybbR - - S - - - protein conserved in bacteria
FMFMHKIL_01307 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FMFMHKIL_01308 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FMFMHKIL_01309 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FMFMHKIL_01310 1.71e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
FMFMHKIL_01311 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FMFMHKIL_01312 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FMFMHKIL_01313 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
FMFMHKIL_01314 1.83e-118 ybcF - - P - - - carbonic anhydrase
FMFMHKIL_01315 1.6e-63 - - - - - - - -
FMFMHKIL_01316 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
FMFMHKIL_01318 9.45e-67 - - - K - - - Helix-turn-helix domain
FMFMHKIL_01319 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
FMFMHKIL_01321 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_01322 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
FMFMHKIL_01323 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
FMFMHKIL_01325 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
FMFMHKIL_01326 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FMFMHKIL_01327 3.28e-156 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
FMFMHKIL_01328 1.61e-218 - - - T - - - His Kinase A (phospho-acceptor) domain
FMFMHKIL_01330 3.26e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
FMFMHKIL_01331 7.4e-193 ybdN - - - - - - -
FMFMHKIL_01332 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
FMFMHKIL_01333 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_01334 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
FMFMHKIL_01335 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
FMFMHKIL_01336 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
FMFMHKIL_01337 3.64e-312 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
FMFMHKIL_01338 1.11e-54 ybyB - - - - - - -
FMFMHKIL_01339 0.0 ybeC - - E - - - amino acid
FMFMHKIL_01340 2.85e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
FMFMHKIL_01341 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
FMFMHKIL_01342 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
FMFMHKIL_01343 2.1e-218 ybfA - - K - - - FR47-like protein
FMFMHKIL_01344 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_01346 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
FMFMHKIL_01347 5.27e-208 ybfH - - EG - - - EamA-like transporter family
FMFMHKIL_01348 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
FMFMHKIL_01349 4.8e-244 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FMFMHKIL_01350 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
FMFMHKIL_01352 2.02e-216 - - - S - - - Alpha/beta hydrolase family
FMFMHKIL_01353 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FMFMHKIL_01354 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
FMFMHKIL_01355 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
FMFMHKIL_01356 1.58e-59 ybfN - - - - - - -
FMFMHKIL_01357 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
FMFMHKIL_01358 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FMFMHKIL_01359 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_01360 3.34e-104 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_01361 2.59e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FMFMHKIL_01362 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
FMFMHKIL_01364 2.82e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
FMFMHKIL_01365 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FMFMHKIL_01366 5.26e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
FMFMHKIL_01367 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
FMFMHKIL_01368 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
FMFMHKIL_01369 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_01370 2.01e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
FMFMHKIL_01371 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
FMFMHKIL_01372 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FMFMHKIL_01373 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_01374 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
FMFMHKIL_01375 4.63e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
FMFMHKIL_01376 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
FMFMHKIL_01377 2.47e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
FMFMHKIL_01378 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
FMFMHKIL_01379 7.31e-218 eamA1 - - EG - - - spore germination
FMFMHKIL_01380 3.71e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_01381 6.21e-214 ycbM - - T - - - Histidine kinase
FMFMHKIL_01382 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_01383 2.87e-148 - - - S - - - ABC-2 family transporter protein
FMFMHKIL_01384 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
FMFMHKIL_01385 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
FMFMHKIL_01386 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
FMFMHKIL_01387 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
FMFMHKIL_01388 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FMFMHKIL_01389 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FMFMHKIL_01390 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FMFMHKIL_01391 4.86e-259 ycbU - - E - - - Selenocysteine lyase
FMFMHKIL_01392 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
FMFMHKIL_01393 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
FMFMHKIL_01394 1.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
FMFMHKIL_01395 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
FMFMHKIL_01396 4.32e-78 - - - S - - - RDD family
FMFMHKIL_01397 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
FMFMHKIL_01398 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
FMFMHKIL_01399 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
FMFMHKIL_01400 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
FMFMHKIL_01401 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
FMFMHKIL_01402 6.81e-222 yccK - - C - - - Aldo keto reductase
FMFMHKIL_01403 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
FMFMHKIL_01404 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_01405 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_01406 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
FMFMHKIL_01407 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
FMFMHKIL_01408 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_01409 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
FMFMHKIL_01410 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
FMFMHKIL_01411 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FMFMHKIL_01412 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FMFMHKIL_01413 5.95e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_01414 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
FMFMHKIL_01415 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
FMFMHKIL_01416 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
FMFMHKIL_01417 1.37e-174 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
FMFMHKIL_01418 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
FMFMHKIL_01419 2.96e-245 yceH - - P - - - Belongs to the TelA family
FMFMHKIL_01420 3.84e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
FMFMHKIL_01421 1.3e-264 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
FMFMHKIL_01422 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
FMFMHKIL_01423 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
FMFMHKIL_01424 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
FMFMHKIL_01425 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
FMFMHKIL_01426 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
FMFMHKIL_01427 0.0 ycgA - - S - - - Membrane
FMFMHKIL_01428 2.72e-105 ycgB - - - - - - -
FMFMHKIL_01429 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
FMFMHKIL_01430 9.79e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
FMFMHKIL_01431 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
FMFMHKIL_01432 0.0 mdr - - EGP - - - the major facilitator superfamily
FMFMHKIL_01433 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_01434 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
FMFMHKIL_01435 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
FMFMHKIL_01436 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_01437 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
FMFMHKIL_01438 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FMFMHKIL_01439 1.43e-53 tmrB - - S - - - AAA domain
FMFMHKIL_01440 2.39e-22 tmrB - - S - - - AAA domain
FMFMHKIL_01442 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FMFMHKIL_01443 1.02e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
FMFMHKIL_01444 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
FMFMHKIL_01445 3.16e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
FMFMHKIL_01446 1.75e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
FMFMHKIL_01447 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
FMFMHKIL_01448 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
FMFMHKIL_01449 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FMFMHKIL_01450 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
FMFMHKIL_01451 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
FMFMHKIL_01452 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
FMFMHKIL_01453 2.32e-200 ycgS - - I - - - alpha/beta hydrolase fold
FMFMHKIL_01454 1.48e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
FMFMHKIL_01455 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
FMFMHKIL_01456 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
FMFMHKIL_01457 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FMFMHKIL_01458 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FMFMHKIL_01459 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
FMFMHKIL_01460 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
FMFMHKIL_01461 1.08e-215 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
FMFMHKIL_01462 1.04e-140 - - - M - - - ErfK YbiS YcfS YnhG
FMFMHKIL_01463 3.76e-288 yciC - - S - - - GTPases (G3E family)
FMFMHKIL_01464 9.69e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
FMFMHKIL_01465 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FMFMHKIL_01468 1.29e-95 yckC - - S - - - membrane
FMFMHKIL_01469 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
FMFMHKIL_01470 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FMFMHKIL_01471 4.78e-91 nin - - S - - - Competence protein J (ComJ)
FMFMHKIL_01472 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
FMFMHKIL_01473 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_01474 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
FMFMHKIL_01475 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
FMFMHKIL_01476 6.05e-86 hxlR - - K - - - transcriptional
FMFMHKIL_01498 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FMFMHKIL_01499 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FMFMHKIL_01500 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
FMFMHKIL_01501 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
FMFMHKIL_01502 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
FMFMHKIL_01503 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
FMFMHKIL_01504 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
FMFMHKIL_01505 1.01e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
FMFMHKIL_01506 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
FMFMHKIL_01508 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
FMFMHKIL_01509 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
FMFMHKIL_01510 1.6e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FMFMHKIL_01511 2.82e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
FMFMHKIL_01512 7.13e-168 yteA - - T - - - COG1734 DnaK suppressor protein
FMFMHKIL_01513 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
FMFMHKIL_01514 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FMFMHKIL_01515 1.29e-192 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
FMFMHKIL_01516 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FMFMHKIL_01517 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
FMFMHKIL_01518 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FMFMHKIL_01519 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
FMFMHKIL_01520 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FMFMHKIL_01521 1.01e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FMFMHKIL_01522 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
FMFMHKIL_01523 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
FMFMHKIL_01524 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
FMFMHKIL_01525 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
FMFMHKIL_01526 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
FMFMHKIL_01527 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
FMFMHKIL_01528 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FMFMHKIL_01529 6.79e-95 ytkA - - S - - - YtkA-like
FMFMHKIL_01531 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
FMFMHKIL_01532 6.47e-81 ytkC - - S - - - Bacteriophage holin family
FMFMHKIL_01533 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
FMFMHKIL_01534 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FMFMHKIL_01535 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
FMFMHKIL_01536 6.26e-239 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
FMFMHKIL_01537 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
FMFMHKIL_01538 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
FMFMHKIL_01539 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FMFMHKIL_01540 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FMFMHKIL_01541 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
FMFMHKIL_01542 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_01543 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FMFMHKIL_01544 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
FMFMHKIL_01545 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
FMFMHKIL_01546 1.59e-135 ytqB - - J - - - Putative rRNA methylase
FMFMHKIL_01547 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
FMFMHKIL_01548 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
FMFMHKIL_01550 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
FMFMHKIL_01551 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_01552 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
FMFMHKIL_01553 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
FMFMHKIL_01554 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_01555 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
FMFMHKIL_01556 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_01557 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
FMFMHKIL_01558 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_01559 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
FMFMHKIL_01560 5.75e-78 yttA - - S - - - Pfam Transposase IS66
FMFMHKIL_01561 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
FMFMHKIL_01562 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
FMFMHKIL_01563 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
FMFMHKIL_01564 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
FMFMHKIL_01565 7.08e-68 ytwF - - P - - - Sulfurtransferase
FMFMHKIL_01566 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
FMFMHKIL_01567 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
FMFMHKIL_01568 5.54e-213 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMFMHKIL_01569 7.08e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
FMFMHKIL_01570 1.53e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_01571 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
FMFMHKIL_01572 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FMFMHKIL_01573 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
FMFMHKIL_01574 6.91e-280 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FMFMHKIL_01575 9.36e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FMFMHKIL_01576 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FMFMHKIL_01577 1.03e-284 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
FMFMHKIL_01578 8.64e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
FMFMHKIL_01579 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
FMFMHKIL_01580 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
FMFMHKIL_01581 0.0 ytdP - - K - - - Transcriptional regulator
FMFMHKIL_01582 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
FMFMHKIL_01583 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
FMFMHKIL_01584 4.78e-94 yteS - - G - - - transport
FMFMHKIL_01585 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
FMFMHKIL_01586 1.55e-149 yteU - - S - - - Integral membrane protein
FMFMHKIL_01587 2.14e-36 yteV - - S - - - Sporulation protein Cse60
FMFMHKIL_01588 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
FMFMHKIL_01589 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
FMFMHKIL_01590 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_01591 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FMFMHKIL_01592 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
FMFMHKIL_01593 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
FMFMHKIL_01594 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
FMFMHKIL_01595 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
FMFMHKIL_01596 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
FMFMHKIL_01597 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FMFMHKIL_01598 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FMFMHKIL_01599 4.04e-211 ytlQ - - - - - - -
FMFMHKIL_01600 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
FMFMHKIL_01601 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
FMFMHKIL_01602 3.02e-192 ytmP - - M - - - Phosphotransferase
FMFMHKIL_01603 9.51e-61 ytzH - - S - - - YtzH-like protein
FMFMHKIL_01604 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FMFMHKIL_01605 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
FMFMHKIL_01606 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
FMFMHKIL_01607 1.17e-67 ytzB - - S - - - small secreted protein
FMFMHKIL_01608 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
FMFMHKIL_01609 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
FMFMHKIL_01610 3.17e-75 ytpP - - CO - - - Thioredoxin
FMFMHKIL_01611 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
FMFMHKIL_01612 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FMFMHKIL_01613 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
FMFMHKIL_01614 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
FMFMHKIL_01615 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FMFMHKIL_01616 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
FMFMHKIL_01617 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
FMFMHKIL_01618 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
FMFMHKIL_01619 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
FMFMHKIL_01620 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
FMFMHKIL_01621 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
FMFMHKIL_01622 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
FMFMHKIL_01623 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
FMFMHKIL_01624 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
FMFMHKIL_01625 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FMFMHKIL_01626 1.85e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FMFMHKIL_01628 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FMFMHKIL_01629 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
FMFMHKIL_01630 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
FMFMHKIL_01631 1.2e-141 yttP - - K - - - Transcriptional regulator
FMFMHKIL_01632 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
FMFMHKIL_01633 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FMFMHKIL_01634 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
FMFMHKIL_01635 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
FMFMHKIL_01636 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FMFMHKIL_01637 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
FMFMHKIL_01638 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FMFMHKIL_01639 0.0 ytcJ - - S - - - amidohydrolase
FMFMHKIL_01640 4.85e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FMFMHKIL_01641 5.87e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
FMFMHKIL_01642 2.36e-111 yteJ - - S - - - RDD family
FMFMHKIL_01643 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
FMFMHKIL_01644 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
FMFMHKIL_01645 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FMFMHKIL_01646 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
FMFMHKIL_01647 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FMFMHKIL_01648 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
FMFMHKIL_01649 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
FMFMHKIL_01650 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
FMFMHKIL_01652 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_01653 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
FMFMHKIL_01654 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
FMFMHKIL_01655 2.31e-127 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
FMFMHKIL_01656 2.15e-193 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
FMFMHKIL_01657 2.71e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
FMFMHKIL_01658 6.75e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_01659 2.64e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_01660 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
FMFMHKIL_01661 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_01662 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
FMFMHKIL_01663 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMFMHKIL_01664 9.41e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
FMFMHKIL_01665 1.41e-304 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
FMFMHKIL_01666 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
FMFMHKIL_01667 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
FMFMHKIL_01668 2.15e-63 ytpI - - S - - - YtpI-like protein
FMFMHKIL_01669 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
FMFMHKIL_01670 1.15e-39 - - - - - - - -
FMFMHKIL_01671 5.98e-111 ytrI - - - - - - -
FMFMHKIL_01672 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
FMFMHKIL_01673 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
FMFMHKIL_01674 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
FMFMHKIL_01675 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FMFMHKIL_01676 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
FMFMHKIL_01677 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FMFMHKIL_01678 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
FMFMHKIL_01679 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
FMFMHKIL_01680 6.42e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
FMFMHKIL_01681 9.38e-95 ytwI - - S - - - membrane
FMFMHKIL_01682 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
FMFMHKIL_01683 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
FMFMHKIL_01684 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
FMFMHKIL_01685 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_01686 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
FMFMHKIL_01687 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FMFMHKIL_01688 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FMFMHKIL_01689 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
FMFMHKIL_01690 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FMFMHKIL_01691 4.54e-205 ytbE - - S - - - reductase
FMFMHKIL_01692 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
FMFMHKIL_01693 9.85e-88 ytcD - - K - - - Transcriptional regulator
FMFMHKIL_01694 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FMFMHKIL_01695 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FMFMHKIL_01696 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FMFMHKIL_01697 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
FMFMHKIL_01698 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
FMFMHKIL_01699 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
FMFMHKIL_01700 5.98e-206 ytxC - - S - - - YtxC-like family
FMFMHKIL_01701 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FMFMHKIL_01702 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
FMFMHKIL_01703 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_01704 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
FMFMHKIL_01705 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FMFMHKIL_01706 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FMFMHKIL_01708 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FMFMHKIL_01709 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
FMFMHKIL_01710 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FMFMHKIL_01711 1.27e-59 ysdA - - S - - - Membrane
FMFMHKIL_01712 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
FMFMHKIL_01713 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
FMFMHKIL_01714 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
FMFMHKIL_01715 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
FMFMHKIL_01716 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
FMFMHKIL_01717 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
FMFMHKIL_01718 1.74e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
FMFMHKIL_01719 3.72e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
FMFMHKIL_01720 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
FMFMHKIL_01721 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
FMFMHKIL_01722 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
FMFMHKIL_01723 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
FMFMHKIL_01724 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
FMFMHKIL_01725 2.94e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
FMFMHKIL_01726 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
FMFMHKIL_01727 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
FMFMHKIL_01728 1.92e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
FMFMHKIL_01729 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
FMFMHKIL_01730 2.57e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMFMHKIL_01731 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FMFMHKIL_01732 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FMFMHKIL_01733 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FMFMHKIL_01734 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FMFMHKIL_01735 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
FMFMHKIL_01736 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
FMFMHKIL_01737 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FMFMHKIL_01738 7.59e-89 yshE - - S ko:K08989 - ko00000 membrane
FMFMHKIL_01739 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FMFMHKIL_01740 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_01741 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
FMFMHKIL_01742 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
FMFMHKIL_01743 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
FMFMHKIL_01745 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
FMFMHKIL_01746 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
FMFMHKIL_01747 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FMFMHKIL_01748 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
FMFMHKIL_01749 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
FMFMHKIL_01750 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
FMFMHKIL_01751 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
FMFMHKIL_01752 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
FMFMHKIL_01753 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
FMFMHKIL_01754 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_01755 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_01756 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
FMFMHKIL_01757 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
FMFMHKIL_01758 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FMFMHKIL_01759 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FMFMHKIL_01760 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
FMFMHKIL_01762 9.59e-48 ysnF - - S - - - protein conserved in bacteria
FMFMHKIL_01763 1.71e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
FMFMHKIL_01765 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
FMFMHKIL_01766 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
FMFMHKIL_01767 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FMFMHKIL_01768 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FMFMHKIL_01769 1.75e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FMFMHKIL_01770 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FMFMHKIL_01771 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FMFMHKIL_01772 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
FMFMHKIL_01773 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FMFMHKIL_01774 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FMFMHKIL_01775 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
FMFMHKIL_01776 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FMFMHKIL_01777 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
FMFMHKIL_01778 4.77e-116 ysxD - - - - - - -
FMFMHKIL_01779 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FMFMHKIL_01780 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
FMFMHKIL_01781 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
FMFMHKIL_01782 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
FMFMHKIL_01783 3.04e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
FMFMHKIL_01784 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
FMFMHKIL_01785 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
FMFMHKIL_01786 9.73e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FMFMHKIL_01787 1.53e-35 - - - - - - - -
FMFMHKIL_01788 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FMFMHKIL_01789 7.42e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
FMFMHKIL_01790 1.81e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
FMFMHKIL_01791 3.08e-206 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
FMFMHKIL_01792 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
FMFMHKIL_01793 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
FMFMHKIL_01794 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
FMFMHKIL_01795 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
FMFMHKIL_01796 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
FMFMHKIL_01797 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
FMFMHKIL_01798 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
FMFMHKIL_01799 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
FMFMHKIL_01800 1.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
FMFMHKIL_01801 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
FMFMHKIL_01802 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
FMFMHKIL_01803 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
FMFMHKIL_01804 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
FMFMHKIL_01805 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FMFMHKIL_01806 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
FMFMHKIL_01807 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
FMFMHKIL_01808 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
FMFMHKIL_01809 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
FMFMHKIL_01810 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
FMFMHKIL_01811 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
FMFMHKIL_01812 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FMFMHKIL_01813 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
FMFMHKIL_01814 2.08e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FMFMHKIL_01815 8.63e-165 yebC - - K - - - transcriptional regulatory protein
FMFMHKIL_01816 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
FMFMHKIL_01817 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
FMFMHKIL_01819 2.32e-152 yrzF - - T - - - serine threonine protein kinase
FMFMHKIL_01820 2.65e-246 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
FMFMHKIL_01821 0.0 csbX - - EGP - - - the major facilitator superfamily
FMFMHKIL_01822 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
FMFMHKIL_01823 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FMFMHKIL_01824 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FMFMHKIL_01825 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
FMFMHKIL_01826 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FMFMHKIL_01827 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FMFMHKIL_01828 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
FMFMHKIL_01829 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
FMFMHKIL_01830 5.83e-143 yrbG - - S - - - membrane
FMFMHKIL_01831 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_01832 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
FMFMHKIL_01833 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FMFMHKIL_01834 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
FMFMHKIL_01835 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
FMFMHKIL_01836 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
FMFMHKIL_01837 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FMFMHKIL_01838 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FMFMHKIL_01839 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FMFMHKIL_01840 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
FMFMHKIL_01842 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
FMFMHKIL_01843 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FMFMHKIL_01844 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
FMFMHKIL_01845 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
FMFMHKIL_01846 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_01847 1.09e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
FMFMHKIL_01848 3.4e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FMFMHKIL_01849 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
FMFMHKIL_01850 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FMFMHKIL_01851 3.39e-106 yrrD - - S - - - protein conserved in bacteria
FMFMHKIL_01852 8.4e-42 yrzR - - - - - - -
FMFMHKIL_01853 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
FMFMHKIL_01854 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMFMHKIL_01855 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMFMHKIL_01856 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
FMFMHKIL_01857 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
FMFMHKIL_01858 8.81e-242 yrrI - - S - - - AI-2E family transporter
FMFMHKIL_01859 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FMFMHKIL_01860 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
FMFMHKIL_01861 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FMFMHKIL_01862 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
FMFMHKIL_01863 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FMFMHKIL_01864 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
FMFMHKIL_01865 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
FMFMHKIL_01866 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
FMFMHKIL_01867 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
FMFMHKIL_01868 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FMFMHKIL_01869 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
FMFMHKIL_01870 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
FMFMHKIL_01871 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
FMFMHKIL_01872 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
FMFMHKIL_01873 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FMFMHKIL_01874 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
FMFMHKIL_01875 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FMFMHKIL_01876 6.93e-49 yrhC - - S - - - YrhC-like protein
FMFMHKIL_01877 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
FMFMHKIL_01878 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
FMFMHKIL_01879 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
FMFMHKIL_01881 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
FMFMHKIL_01883 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
FMFMHKIL_01884 7.42e-125 yrhH - - Q - - - methyltransferase
FMFMHKIL_01885 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
FMFMHKIL_01886 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
FMFMHKIL_01887 1.55e-61 yrhK - - S - - - YrhK-like protein
FMFMHKIL_01888 1.15e-70 oatA - - I - - - Acyltransferase family
FMFMHKIL_01889 0.0 oatA - - I - - - Acyltransferase family
FMFMHKIL_01890 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
FMFMHKIL_01891 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_01892 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
FMFMHKIL_01893 5.63e-137 yrhP - - E - - - LysE type translocator
FMFMHKIL_01894 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_01895 0.0 levR - - K - - - PTS system fructose IIA component
FMFMHKIL_01896 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
FMFMHKIL_01897 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
FMFMHKIL_01898 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
FMFMHKIL_01899 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
FMFMHKIL_01900 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
FMFMHKIL_01901 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
FMFMHKIL_01902 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
FMFMHKIL_01903 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
FMFMHKIL_01904 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
FMFMHKIL_01905 6.11e-36 yraE - - - ko:K06440 - ko00000 -
FMFMHKIL_01906 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FMFMHKIL_01907 7.91e-83 yraF - - M - - - Spore coat protein
FMFMHKIL_01908 1.2e-49 yraG - - - ko:K06440 - ko00000 -
FMFMHKIL_01909 5.45e-86 - - - E - - - Glyoxalase-like domain
FMFMHKIL_01910 1.69e-80 - - - T - - - sh3 domain protein
FMFMHKIL_01911 6.61e-80 - - - T - - - sh3 domain protein
FMFMHKIL_01912 2.33e-194 - - - S - - - Alpha beta hydrolase
FMFMHKIL_01913 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_01914 9.5e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
FMFMHKIL_01915 1.71e-262 yraM - - S - - - PrpF protein
FMFMHKIL_01916 2.97e-210 yraN - - K - - - Transcriptional regulator
FMFMHKIL_01917 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
FMFMHKIL_01918 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
FMFMHKIL_01919 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_01920 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
FMFMHKIL_01921 9.71e-31 epsA - - I - - - Passenger-associated-transport-repeat
FMFMHKIL_01922 1.62e-63 - - - S - - - YjbR
FMFMHKIL_01923 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
FMFMHKIL_01924 3.1e-126 - - - S - - - Flavin reductase like domain
FMFMHKIL_01925 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
FMFMHKIL_01926 1.02e-192 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
FMFMHKIL_01927 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_01928 4.11e-268 - - - P - - - Major Facilitator Superfamily
FMFMHKIL_01930 6.71e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
FMFMHKIL_01931 4.62e-160 yrpD - - S - - - Domain of unknown function, YrpD
FMFMHKIL_01932 1.39e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
FMFMHKIL_01933 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
FMFMHKIL_01934 5.77e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
FMFMHKIL_01935 1.17e-117 yrdA - - S - - - DinB family
FMFMHKIL_01936 8.58e-71 - - - S - - - Protein of unknown function (DUF2568)
FMFMHKIL_01937 7.38e-131 yrdC - - Q - - - Isochorismatase family
FMFMHKIL_01938 8.91e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
FMFMHKIL_01939 5.04e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
FMFMHKIL_01940 1.18e-103 bkdR - - K - - - helix_turn_helix ASNC type
FMFMHKIL_01941 9.34e-176 azlC - - E - - - AzlC protein
FMFMHKIL_01942 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
FMFMHKIL_01943 1.43e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
FMFMHKIL_01944 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
FMFMHKIL_01945 6.6e-201 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
FMFMHKIL_01946 1.44e-86 yodA - - S - - - tautomerase
FMFMHKIL_01947 2e-211 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
FMFMHKIL_01948 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FMFMHKIL_01949 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FMFMHKIL_01950 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
FMFMHKIL_01951 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FMFMHKIL_01952 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FMFMHKIL_01953 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
FMFMHKIL_01954 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FMFMHKIL_01955 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
FMFMHKIL_01956 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
FMFMHKIL_01957 0.0 ylqG - - - - - - -
FMFMHKIL_01958 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FMFMHKIL_01959 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FMFMHKIL_01960 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FMFMHKIL_01961 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
FMFMHKIL_01962 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FMFMHKIL_01963 3.41e-80 ylqD - - S - - - YlqD protein
FMFMHKIL_01964 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
FMFMHKIL_01965 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
FMFMHKIL_01966 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FMFMHKIL_01967 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FMFMHKIL_01968 1.67e-114 - - - - - - - -
FMFMHKIL_01969 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FMFMHKIL_01970 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
FMFMHKIL_01971 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FMFMHKIL_01972 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
FMFMHKIL_01973 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
FMFMHKIL_01974 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
FMFMHKIL_01975 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FMFMHKIL_01976 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
FMFMHKIL_01977 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FMFMHKIL_01978 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
FMFMHKIL_01979 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
FMFMHKIL_01980 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
FMFMHKIL_01981 3.65e-78 yloU - - S - - - protein conserved in bacteria
FMFMHKIL_01982 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
FMFMHKIL_01983 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
FMFMHKIL_01984 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
FMFMHKIL_01985 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FMFMHKIL_01986 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
FMFMHKIL_01987 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
FMFMHKIL_01988 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FMFMHKIL_01989 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FMFMHKIL_01990 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FMFMHKIL_01991 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FMFMHKIL_01992 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FMFMHKIL_01993 7.28e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FMFMHKIL_01994 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FMFMHKIL_01995 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
FMFMHKIL_01996 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
FMFMHKIL_01997 8.41e-202 yloC - - S - - - stress-induced protein
FMFMHKIL_01998 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
FMFMHKIL_01999 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
FMFMHKIL_02000 1.08e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
FMFMHKIL_02001 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
FMFMHKIL_02002 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
FMFMHKIL_02003 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
FMFMHKIL_02004 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
FMFMHKIL_02005 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
FMFMHKIL_02006 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
FMFMHKIL_02008 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FMFMHKIL_02009 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FMFMHKIL_02010 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FMFMHKIL_02011 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
FMFMHKIL_02012 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
FMFMHKIL_02013 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
FMFMHKIL_02014 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FMFMHKIL_02015 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
FMFMHKIL_02016 3.71e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
FMFMHKIL_02017 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FMFMHKIL_02018 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
FMFMHKIL_02019 5.47e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FMFMHKIL_02020 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
FMFMHKIL_02021 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FMFMHKIL_02022 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
FMFMHKIL_02023 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
FMFMHKIL_02024 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
FMFMHKIL_02025 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FMFMHKIL_02026 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FMFMHKIL_02027 7.23e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
FMFMHKIL_02028 3.58e-51 ylmC - - S - - - sporulation protein
FMFMHKIL_02029 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
FMFMHKIL_02030 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
FMFMHKIL_02031 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_02032 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_02033 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
FMFMHKIL_02035 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
FMFMHKIL_02036 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FMFMHKIL_02037 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FMFMHKIL_02038 5.37e-76 sbp - - S - - - small basic protein
FMFMHKIL_02039 1.03e-123 ylxX - - S - - - protein conserved in bacteria
FMFMHKIL_02040 4.5e-142 ylxW - - S - - - protein conserved in bacteria
FMFMHKIL_02041 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FMFMHKIL_02042 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
FMFMHKIL_02043 4.66e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FMFMHKIL_02044 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
FMFMHKIL_02045 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FMFMHKIL_02046 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FMFMHKIL_02047 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FMFMHKIL_02048 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
FMFMHKIL_02049 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
FMFMHKIL_02050 3.42e-68 ftsL - - D - - - Essential cell division protein
FMFMHKIL_02051 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FMFMHKIL_02052 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
FMFMHKIL_02053 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FMFMHKIL_02054 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FMFMHKIL_02055 1.33e-115 ylbP - - K - - - n-acetyltransferase
FMFMHKIL_02056 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
FMFMHKIL_02057 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
FMFMHKIL_02058 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
FMFMHKIL_02060 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
FMFMHKIL_02061 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
FMFMHKIL_02062 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
FMFMHKIL_02063 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
FMFMHKIL_02064 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FMFMHKIL_02065 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
FMFMHKIL_02066 8.8e-52 ylbG - - S - - - UPF0298 protein
FMFMHKIL_02067 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
FMFMHKIL_02068 1.73e-48 ylbE - - S - - - YlbE-like protein
FMFMHKIL_02069 3.24e-89 ylbD - - S - - - Putative coat protein
FMFMHKIL_02070 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
FMFMHKIL_02071 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
FMFMHKIL_02072 1.61e-81 ylbA - - S - - - YugN-like family
FMFMHKIL_02073 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
FMFMHKIL_02074 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
FMFMHKIL_02075 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
FMFMHKIL_02076 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FMFMHKIL_02077 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
FMFMHKIL_02078 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FMFMHKIL_02079 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
FMFMHKIL_02080 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FMFMHKIL_02081 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
FMFMHKIL_02082 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
FMFMHKIL_02083 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
FMFMHKIL_02084 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FMFMHKIL_02085 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
FMFMHKIL_02086 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FMFMHKIL_02087 8.92e-44 ylaI - - S - - - protein conserved in bacteria
FMFMHKIL_02088 4.4e-63 ylaH - - S - - - YlaH-like protein
FMFMHKIL_02089 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
FMFMHKIL_02090 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
FMFMHKIL_02091 1.74e-57 ylaE - - - - - - -
FMFMHKIL_02093 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_02094 1.44e-56 ylaB - - - - - - -
FMFMHKIL_02095 0.0 ylaA - - - - - - -
FMFMHKIL_02096 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
FMFMHKIL_02097 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FMFMHKIL_02098 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
FMFMHKIL_02099 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
FMFMHKIL_02100 4.48e-35 ykzI - - - - - - -
FMFMHKIL_02101 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
FMFMHKIL_02102 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
FMFMHKIL_02103 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
FMFMHKIL_02104 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
FMFMHKIL_02105 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FMFMHKIL_02106 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FMFMHKIL_02107 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FMFMHKIL_02108 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FMFMHKIL_02109 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
FMFMHKIL_02110 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
FMFMHKIL_02111 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FMFMHKIL_02112 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
FMFMHKIL_02113 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
FMFMHKIL_02114 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FMFMHKIL_02115 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FMFMHKIL_02116 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
FMFMHKIL_02117 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
FMFMHKIL_02118 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
FMFMHKIL_02119 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
FMFMHKIL_02120 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
FMFMHKIL_02121 1.09e-18 - - - S - - - Uncharacterized protein YkpC
FMFMHKIL_02122 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
FMFMHKIL_02123 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FMFMHKIL_02124 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FMFMHKIL_02125 5.43e-52 ykoA - - - - - - -
FMFMHKIL_02126 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FMFMHKIL_02127 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
FMFMHKIL_02128 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
FMFMHKIL_02129 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02130 1.58e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
FMFMHKIL_02131 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_02132 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMFMHKIL_02133 5.34e-150 yknW - - S - - - Yip1 domain
FMFMHKIL_02134 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
FMFMHKIL_02135 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
FMFMHKIL_02136 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FMFMHKIL_02137 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
FMFMHKIL_02138 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
FMFMHKIL_02139 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
FMFMHKIL_02140 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FMFMHKIL_02141 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
FMFMHKIL_02142 2.43e-200 yknT - - - ko:K06437 - ko00000 -
FMFMHKIL_02143 4.71e-122 rok - - K - - - Repressor of ComK
FMFMHKIL_02144 1.47e-104 ykuV - - CO - - - thiol-disulfide
FMFMHKIL_02145 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
FMFMHKIL_02146 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
FMFMHKIL_02147 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
FMFMHKIL_02148 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FMFMHKIL_02149 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FMFMHKIL_02150 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
FMFMHKIL_02151 7.7e-226 ykuO - - - - - - -
FMFMHKIL_02152 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
FMFMHKIL_02153 6.52e-216 ccpC - - K - - - Transcriptional regulator
FMFMHKIL_02154 5.15e-100 ykuL - - S - - - CBS domain
FMFMHKIL_02155 7.83e-38 ykzF - - S - - - Antirepressor AbbA
FMFMHKIL_02156 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
FMFMHKIL_02157 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
FMFMHKIL_02158 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
FMFMHKIL_02159 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_02160 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
FMFMHKIL_02161 5.84e-115 ykuD - - S - - - protein conserved in bacteria
FMFMHKIL_02162 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_02163 3.71e-110 ykyB - - S - - - YkyB-like protein
FMFMHKIL_02164 2.02e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
FMFMHKIL_02165 1.05e-22 - - - - - - - -
FMFMHKIL_02166 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMFMHKIL_02167 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_02168 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
FMFMHKIL_02169 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
FMFMHKIL_02170 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
FMFMHKIL_02171 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
FMFMHKIL_02172 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_02173 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
FMFMHKIL_02174 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02175 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FMFMHKIL_02176 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
FMFMHKIL_02177 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_02178 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
FMFMHKIL_02180 6.34e-228 ykvZ - - K - - - Transcriptional regulator
FMFMHKIL_02181 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
FMFMHKIL_02182 3.99e-09 - - - - - - - -
FMFMHKIL_02183 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
FMFMHKIL_02184 1.31e-113 stoA - - CO - - - thiol-disulfide
FMFMHKIL_02185 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_02186 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
FMFMHKIL_02187 2.5e-39 - - - - - - - -
FMFMHKIL_02188 5.43e-35 ykvS - - S - - - protein conserved in bacteria
FMFMHKIL_02189 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
FMFMHKIL_02190 1.75e-204 - - - G - - - Glycosyl hydrolases family 18
FMFMHKIL_02191 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
FMFMHKIL_02192 1.82e-273 - - - M - - - Glycosyl transferases group 1
FMFMHKIL_02193 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_02194 2.8e-81 ykvN - - K - - - Transcriptional regulator
FMFMHKIL_02195 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FMFMHKIL_02196 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FMFMHKIL_02197 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
FMFMHKIL_02198 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FMFMHKIL_02199 2.36e-227 ykvI - - S - - - membrane
FMFMHKIL_02200 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
FMFMHKIL_02201 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
FMFMHKIL_02202 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
FMFMHKIL_02203 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
FMFMHKIL_02204 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
FMFMHKIL_02205 5.62e-93 eag - - - - - - -
FMFMHKIL_02207 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
FMFMHKIL_02208 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FMFMHKIL_02209 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
FMFMHKIL_02210 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FMFMHKIL_02211 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
FMFMHKIL_02212 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMFMHKIL_02213 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FMFMHKIL_02214 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FMFMHKIL_02215 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FMFMHKIL_02217 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FMFMHKIL_02218 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_02219 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
FMFMHKIL_02220 1.77e-28 ykzE - - - - - - -
FMFMHKIL_02222 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
FMFMHKIL_02223 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
FMFMHKIL_02224 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
FMFMHKIL_02225 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
FMFMHKIL_02226 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
FMFMHKIL_02227 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_02228 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
FMFMHKIL_02229 1.71e-143 ykoX - - S - - - membrane-associated protein
FMFMHKIL_02230 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
FMFMHKIL_02231 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FMFMHKIL_02232 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
FMFMHKIL_02233 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_02234 0.0 ykoS - - - - - - -
FMFMHKIL_02235 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
FMFMHKIL_02236 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
FMFMHKIL_02237 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
FMFMHKIL_02238 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
FMFMHKIL_02239 3.04e-36 ykoL - - - - - - -
FMFMHKIL_02240 1.63e-25 - - - - - - - -
FMFMHKIL_02241 1.49e-70 tnrA - - K - - - transcriptional
FMFMHKIL_02242 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
FMFMHKIL_02244 1.45e-08 - - - - - - - -
FMFMHKIL_02245 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
FMFMHKIL_02246 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
FMFMHKIL_02247 3.13e-309 ykoH - - T - - - Histidine kinase
FMFMHKIL_02248 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_02249 2.34e-140 ykoF - - S - - - YKOF-related Family
FMFMHKIL_02250 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
FMFMHKIL_02251 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_02252 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
FMFMHKIL_02253 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FMFMHKIL_02254 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_02255 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FMFMHKIL_02256 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
FMFMHKIL_02257 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
FMFMHKIL_02258 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
FMFMHKIL_02259 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
FMFMHKIL_02261 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FMFMHKIL_02262 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FMFMHKIL_02263 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
FMFMHKIL_02264 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
FMFMHKIL_02265 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
FMFMHKIL_02266 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FMFMHKIL_02267 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
FMFMHKIL_02268 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
FMFMHKIL_02269 5.85e-13 - - - - - - - -
FMFMHKIL_02270 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FMFMHKIL_02271 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
FMFMHKIL_02272 4.37e-206 ykgA - - E - - - Amidinotransferase
FMFMHKIL_02273 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
FMFMHKIL_02274 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_02275 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FMFMHKIL_02276 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
FMFMHKIL_02277 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
FMFMHKIL_02279 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
FMFMHKIL_02280 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
FMFMHKIL_02281 9.02e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_02282 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMFMHKIL_02283 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
FMFMHKIL_02284 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
FMFMHKIL_02285 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FMFMHKIL_02287 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_02288 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMFMHKIL_02289 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
FMFMHKIL_02290 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
FMFMHKIL_02291 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
FMFMHKIL_02292 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
FMFMHKIL_02293 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
FMFMHKIL_02294 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
FMFMHKIL_02295 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
FMFMHKIL_02296 1.15e-52 xhlB - - S - - - SPP1 phage holin
FMFMHKIL_02297 2.21e-51 xhlA - - S - - - Haemolysin XhlA
FMFMHKIL_02298 2.21e-193 xepA - - - - - - -
FMFMHKIL_02299 6.35e-31 xkdX - - - - - - -
FMFMHKIL_02300 1.28e-59 xkdW - - S - - - XkdW protein
FMFMHKIL_02301 1.87e-219 - - - - - - - -
FMFMHKIL_02302 4.43e-56 - - - - - - - -
FMFMHKIL_02303 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
FMFMHKIL_02304 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FMFMHKIL_02305 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
FMFMHKIL_02306 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
FMFMHKIL_02307 1.56e-230 xkdQ - - G - - - NLP P60 protein
FMFMHKIL_02308 4.25e-152 xkdP - - S - - - Lysin motif
FMFMHKIL_02309 0.0 xkdO - - L - - - Transglycosylase SLT domain
FMFMHKIL_02310 5.91e-38 ypzH - - - - - - -
FMFMHKIL_02311 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
FMFMHKIL_02312 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
FMFMHKIL_02313 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
FMFMHKIL_02314 2.5e-175 yphF - - - - - - -
FMFMHKIL_02315 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FMFMHKIL_02316 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FMFMHKIL_02317 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
FMFMHKIL_02318 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
FMFMHKIL_02319 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
FMFMHKIL_02320 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FMFMHKIL_02321 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
FMFMHKIL_02322 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
FMFMHKIL_02323 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
FMFMHKIL_02324 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FMFMHKIL_02325 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FMFMHKIL_02326 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
FMFMHKIL_02327 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FMFMHKIL_02328 2.48e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FMFMHKIL_02329 8.44e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
FMFMHKIL_02330 5.25e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
FMFMHKIL_02331 3.12e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FMFMHKIL_02332 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FMFMHKIL_02333 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FMFMHKIL_02334 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
FMFMHKIL_02335 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FMFMHKIL_02336 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
FMFMHKIL_02337 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
FMFMHKIL_02338 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
FMFMHKIL_02339 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
FMFMHKIL_02340 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
FMFMHKIL_02341 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
FMFMHKIL_02342 1.15e-125 ypjA - - S - - - membrane
FMFMHKIL_02343 6.84e-183 ypjB - - S - - - sporulation protein
FMFMHKIL_02344 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
FMFMHKIL_02345 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
FMFMHKIL_02346 6.89e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FMFMHKIL_02347 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
FMFMHKIL_02348 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
FMFMHKIL_02349 1.65e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
FMFMHKIL_02350 3.7e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FMFMHKIL_02351 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FMFMHKIL_02352 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
FMFMHKIL_02353 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FMFMHKIL_02354 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FMFMHKIL_02355 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
FMFMHKIL_02356 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
FMFMHKIL_02357 2.27e-103 ypmB - - S - - - protein conserved in bacteria
FMFMHKIL_02358 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
FMFMHKIL_02359 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
FMFMHKIL_02360 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
FMFMHKIL_02361 5.92e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FMFMHKIL_02362 1.17e-120 ypoC - - - - - - -
FMFMHKIL_02363 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FMFMHKIL_02364 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FMFMHKIL_02365 1.03e-237 yppC - - S - - - Protein of unknown function (DUF2515)
FMFMHKIL_02368 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
FMFMHKIL_02369 2.27e-11 - - - S - - - YppF-like protein
FMFMHKIL_02370 8.72e-68 yppG - - S - - - YppG-like protein
FMFMHKIL_02371 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
FMFMHKIL_02372 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
FMFMHKIL_02373 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
FMFMHKIL_02374 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
FMFMHKIL_02375 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
FMFMHKIL_02376 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FMFMHKIL_02377 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
FMFMHKIL_02379 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
FMFMHKIL_02380 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_02381 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FMFMHKIL_02382 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
FMFMHKIL_02383 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
FMFMHKIL_02384 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
FMFMHKIL_02385 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
FMFMHKIL_02386 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FMFMHKIL_02387 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FMFMHKIL_02388 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
FMFMHKIL_02389 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
FMFMHKIL_02390 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
FMFMHKIL_02391 0.0 ypbR - - S - - - Dynamin family
FMFMHKIL_02392 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
FMFMHKIL_02393 1.08e-11 - - - - - - - -
FMFMHKIL_02394 2.26e-213 ypcP - - L - - - 5'3' exonuclease
FMFMHKIL_02395 5.23e-05 - - - - ko:K06429 - ko00000 -
FMFMHKIL_02396 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
FMFMHKIL_02397 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FMFMHKIL_02398 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
FMFMHKIL_02399 1.54e-37 ypeQ - - S - - - Zinc-finger
FMFMHKIL_02400 5.22e-41 - - - S - - - Protein of unknown function (DUF2564)
FMFMHKIL_02401 1.17e-22 degR - - - - - - -
FMFMHKIL_02402 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
FMFMHKIL_02403 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
FMFMHKIL_02404 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FMFMHKIL_02405 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
FMFMHKIL_02406 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
FMFMHKIL_02407 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
FMFMHKIL_02408 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
FMFMHKIL_02409 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
FMFMHKIL_02410 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
FMFMHKIL_02411 3.47e-148 ypjP - - S - - - YpjP-like protein
FMFMHKIL_02412 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
FMFMHKIL_02413 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FMFMHKIL_02414 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FMFMHKIL_02415 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FMFMHKIL_02416 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
FMFMHKIL_02417 1.4e-236 yplP - - K - - - Transcriptional regulator
FMFMHKIL_02418 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FMFMHKIL_02419 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
FMFMHKIL_02420 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
FMFMHKIL_02421 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
FMFMHKIL_02422 6.8e-129 ypmS - - S - - - protein conserved in bacteria
FMFMHKIL_02423 2.13e-40 ypmT - - S - - - Uncharacterized ympT
FMFMHKIL_02424 9.99e-290 mepA - - V - - - MATE efflux family protein
FMFMHKIL_02425 4.14e-94 ypoP - - K - - - transcriptional
FMFMHKIL_02426 1.4e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FMFMHKIL_02427 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
FMFMHKIL_02428 4.75e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
FMFMHKIL_02429 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
FMFMHKIL_02430 4.7e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
FMFMHKIL_02431 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
FMFMHKIL_02432 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
FMFMHKIL_02433 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
FMFMHKIL_02434 9.78e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
FMFMHKIL_02436 2.34e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMFMHKIL_02437 3.27e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FMFMHKIL_02438 2.71e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FMFMHKIL_02439 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
FMFMHKIL_02440 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
FMFMHKIL_02441 1.36e-251 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
FMFMHKIL_02442 0.0 - - - S - - - Recombinase
FMFMHKIL_02443 9.2e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
FMFMHKIL_02444 8.25e-168 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
FMFMHKIL_02445 3.69e-85 - - - G - - - SMI1-KNR4 cell-wall
FMFMHKIL_02446 1.42e-167 - - - V - - - HNH endonuclease
FMFMHKIL_02447 2e-288 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FMFMHKIL_02448 1.87e-43 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FMFMHKIL_02449 1.25e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
FMFMHKIL_02450 3.47e-129 yokK - - S - - - SMI1 / KNR4 family
FMFMHKIL_02451 1.76e-126 - - - J - - - Acetyltransferase (GNAT) domain
FMFMHKIL_02455 1.42e-55 - - - - - - - -
FMFMHKIL_02456 7.45e-54 - - - S - - - YolD-like protein
FMFMHKIL_02457 6.88e-296 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FMFMHKIL_02459 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
FMFMHKIL_02476 6.37e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
FMFMHKIL_02477 1.58e-36 - - - - - - - -
FMFMHKIL_02478 3.18e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
FMFMHKIL_02479 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FMFMHKIL_02480 0.0 ygaK - - C - - - Berberine and berberine like
FMFMHKIL_02482 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
FMFMHKIL_02483 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
FMFMHKIL_02484 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
FMFMHKIL_02485 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FMFMHKIL_02486 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
FMFMHKIL_02488 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FMFMHKIL_02489 2.79e-102 ygaO - - - - - - -
FMFMHKIL_02490 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02492 1.92e-147 yhzB - - S - - - B3/4 domain
FMFMHKIL_02493 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FMFMHKIL_02494 1.32e-223 yhbB - - S - - - Putative amidase domain
FMFMHKIL_02495 5.37e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FMFMHKIL_02496 1.38e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
FMFMHKIL_02497 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
FMFMHKIL_02498 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
FMFMHKIL_02499 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
FMFMHKIL_02500 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
FMFMHKIL_02501 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
FMFMHKIL_02502 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
FMFMHKIL_02503 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
FMFMHKIL_02504 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
FMFMHKIL_02505 3.95e-59 yhcC - - - - - - -
FMFMHKIL_02506 2.92e-69 - - - - - - - -
FMFMHKIL_02507 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02508 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_02509 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_02510 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FMFMHKIL_02511 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
FMFMHKIL_02512 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
FMFMHKIL_02513 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
FMFMHKIL_02514 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FMFMHKIL_02515 1.13e-70 yhcM - - - - - - -
FMFMHKIL_02516 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FMFMHKIL_02517 3.64e-223 yhcP - - - - - - -
FMFMHKIL_02518 1.68e-146 yhcQ - - M - - - Spore coat protein
FMFMHKIL_02519 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FMFMHKIL_02520 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
FMFMHKIL_02521 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
FMFMHKIL_02522 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
FMFMHKIL_02523 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
FMFMHKIL_02524 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
FMFMHKIL_02525 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FMFMHKIL_02526 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMFMHKIL_02527 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FMFMHKIL_02528 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
FMFMHKIL_02529 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FMFMHKIL_02530 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FMFMHKIL_02531 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
FMFMHKIL_02532 7.33e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_02533 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_02534 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
FMFMHKIL_02535 1.65e-51 yhdB - - S - - - YhdB-like protein
FMFMHKIL_02536 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
FMFMHKIL_02537 1.2e-268 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
FMFMHKIL_02538 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
FMFMHKIL_02539 1.51e-306 ygxB - - M - - - Conserved TM helix
FMFMHKIL_02540 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
FMFMHKIL_02541 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
FMFMHKIL_02542 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
FMFMHKIL_02543 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02544 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
FMFMHKIL_02545 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_02546 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
FMFMHKIL_02547 2.48e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FMFMHKIL_02548 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_02549 2.05e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_02550 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
FMFMHKIL_02551 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
FMFMHKIL_02552 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_02553 1.93e-243 yhdN - - C - - - Aldo keto reductase
FMFMHKIL_02554 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FMFMHKIL_02555 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
FMFMHKIL_02556 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
FMFMHKIL_02557 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
FMFMHKIL_02558 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
FMFMHKIL_02559 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FMFMHKIL_02560 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FMFMHKIL_02561 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
FMFMHKIL_02562 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
FMFMHKIL_02563 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
FMFMHKIL_02564 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
FMFMHKIL_02565 5.7e-200 nodB1 - - G - - - deacetylase
FMFMHKIL_02566 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
FMFMHKIL_02567 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
FMFMHKIL_02568 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
FMFMHKIL_02569 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
FMFMHKIL_02570 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
FMFMHKIL_02571 3.31e-143 yheG - - GM - - - NAD(P)H-binding
FMFMHKIL_02572 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
FMFMHKIL_02573 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
FMFMHKIL_02574 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
FMFMHKIL_02575 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
FMFMHKIL_02576 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
FMFMHKIL_02577 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
FMFMHKIL_02578 2.24e-262 yhaZ - - L - - - DNA alkylation repair enzyme
FMFMHKIL_02579 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
FMFMHKIL_02580 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
FMFMHKIL_02581 7.54e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
FMFMHKIL_02582 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
FMFMHKIL_02584 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
FMFMHKIL_02585 2.29e-36 - - - S - - - YhzD-like protein
FMFMHKIL_02586 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_02587 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
FMFMHKIL_02588 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
FMFMHKIL_02589 0.0 yhaN - - L - - - AAA domain
FMFMHKIL_02590 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
FMFMHKIL_02591 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
FMFMHKIL_02592 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FMFMHKIL_02593 1.4e-116 yhaK - - S - - - Putative zincin peptidase
FMFMHKIL_02594 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
FMFMHKIL_02595 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
FMFMHKIL_02596 1.74e-54 yhaH - - S - - - YtxH-like protein
FMFMHKIL_02597 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
FMFMHKIL_02598 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FMFMHKIL_02599 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
FMFMHKIL_02600 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
FMFMHKIL_02601 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
FMFMHKIL_02602 1.01e-161 ecsC - - S - - - EcsC protein family
FMFMHKIL_02603 1.48e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
FMFMHKIL_02604 2.31e-313 yhfA - - C - - - membrane
FMFMHKIL_02605 1.23e-45 - - - C - - - Rubrerythrin
FMFMHKIL_02606 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
FMFMHKIL_02607 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FMFMHKIL_02608 1.76e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FMFMHKIL_02609 5.66e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
FMFMHKIL_02610 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FMFMHKIL_02611 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_02612 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
FMFMHKIL_02613 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FMFMHKIL_02614 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
FMFMHKIL_02615 2.68e-253 yhfE - - G - - - peptidase M42
FMFMHKIL_02616 6.22e-93 - - - S - - - ASCH
FMFMHKIL_02617 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FMFMHKIL_02618 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
FMFMHKIL_02619 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
FMFMHKIL_02620 1.01e-141 yhfK - - GM - - - NmrA-like family
FMFMHKIL_02621 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
FMFMHKIL_02622 5.6e-85 yhfM - - - - - - -
FMFMHKIL_02623 1.37e-307 yhfN - - O - - - Peptidase M48
FMFMHKIL_02624 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_02625 1.47e-100 - - - K - - - acetyltransferase
FMFMHKIL_02626 8.03e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
FMFMHKIL_02627 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
FMFMHKIL_02628 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
FMFMHKIL_02629 1.48e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
FMFMHKIL_02630 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
FMFMHKIL_02631 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
FMFMHKIL_02632 2.62e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
FMFMHKIL_02633 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
FMFMHKIL_02634 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_02635 9.84e-45 yhzC - - S - - - IDEAL
FMFMHKIL_02636 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
FMFMHKIL_02637 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
FMFMHKIL_02638 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
FMFMHKIL_02639 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FMFMHKIL_02640 9.31e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
FMFMHKIL_02641 2.12e-77 yhjD - - - - - - -
FMFMHKIL_02642 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
FMFMHKIL_02643 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FMFMHKIL_02644 0.0 yhjG - - CH - - - FAD binding domain
FMFMHKIL_02645 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_02646 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
FMFMHKIL_02647 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
FMFMHKIL_02648 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
FMFMHKIL_02649 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
FMFMHKIL_02650 1.07e-239 yhjM - - K - - - Transcriptional regulator
FMFMHKIL_02651 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
FMFMHKIL_02652 4.25e-271 - - - EGP - - - Transmembrane secretion effector
FMFMHKIL_02653 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
FMFMHKIL_02654 2.19e-100 yhjR - - S - - - Rubrerythrin
FMFMHKIL_02655 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
FMFMHKIL_02656 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
FMFMHKIL_02657 1.63e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FMFMHKIL_02658 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
FMFMHKIL_02659 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
FMFMHKIL_02660 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
FMFMHKIL_02661 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
FMFMHKIL_02662 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
FMFMHKIL_02663 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
FMFMHKIL_02664 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
FMFMHKIL_02665 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
FMFMHKIL_02666 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
FMFMHKIL_02667 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
FMFMHKIL_02668 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
FMFMHKIL_02669 1.02e-74 yisL - - S - - - UPF0344 protein
FMFMHKIL_02670 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
FMFMHKIL_02671 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
FMFMHKIL_02672 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
FMFMHKIL_02673 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
FMFMHKIL_02674 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
FMFMHKIL_02675 1.01e-310 yisQ - - V - - - Mate efflux family protein
FMFMHKIL_02676 4.04e-207 yisR - - K - - - Transcriptional regulator
FMFMHKIL_02677 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
FMFMHKIL_02678 5.17e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
FMFMHKIL_02679 9.94e-120 yisT - - S - - - DinB family
FMFMHKIL_02680 5.96e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
FMFMHKIL_02681 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_02682 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
FMFMHKIL_02683 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FMFMHKIL_02684 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
FMFMHKIL_02685 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
FMFMHKIL_02686 2.15e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
FMFMHKIL_02687 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
FMFMHKIL_02688 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
FMFMHKIL_02689 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
FMFMHKIL_02690 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
FMFMHKIL_02691 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_02692 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
FMFMHKIL_02693 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
FMFMHKIL_02694 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
FMFMHKIL_02695 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
FMFMHKIL_02696 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
FMFMHKIL_02697 4.16e-122 - - - - - - - -
FMFMHKIL_02698 1.42e-218 - - - - - - - -
FMFMHKIL_02699 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
FMFMHKIL_02700 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
FMFMHKIL_02701 6.11e-120 - - - - - - - -
FMFMHKIL_02702 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
FMFMHKIL_02703 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
FMFMHKIL_02704 1.22e-88 - - - - - - - -
FMFMHKIL_02706 5.49e-156 - - - - - - - -
FMFMHKIL_02707 3.16e-102 - - - - - - - -
FMFMHKIL_02708 1.09e-115 - - - - - - - -
FMFMHKIL_02709 6.41e-75 - - - - - - - -
FMFMHKIL_02712 1.56e-69 - - - - - - - -
FMFMHKIL_02713 5.87e-33 - - - - - - - -
FMFMHKIL_02716 1.12e-110 - - - - - - - -
FMFMHKIL_02717 3.06e-89 - - - - - - - -
FMFMHKIL_02718 4.75e-245 - - - A - - - Belongs to the 'phage' integrase family
FMFMHKIL_02719 3.31e-52 - - - K - - - Helix-turn-helix
FMFMHKIL_02720 1.55e-66 - - - - - - - -
FMFMHKIL_02721 0.0 - - - S - - - peptidoglycan catabolic process
FMFMHKIL_02722 2.48e-106 - - - S - - - Phage tail protein
FMFMHKIL_02723 0.0 - - - S - - - Pfam Transposase IS66
FMFMHKIL_02724 6.68e-143 - - - - - - - -
FMFMHKIL_02725 2.12e-55 - - - S - - - virus tail, fiber
FMFMHKIL_02726 3.07e-111 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
FMFMHKIL_02728 3.98e-49 - - - S - - - Bacteriophage holin
FMFMHKIL_02729 1.29e-125 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
FMFMHKIL_02731 4.81e-53 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FMFMHKIL_02733 2.18e-134 trkA - - P ko:K07222 - ko00000 Oxidoreductase
FMFMHKIL_02734 1.64e-202 - - - K - - - Transcriptional regulator
FMFMHKIL_02735 2.84e-215 yrdR - - EG - - - EamA-like transporter family
FMFMHKIL_02736 2.45e-23 - - - S - - - YrzO-like protein
FMFMHKIL_02737 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
FMFMHKIL_02738 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
FMFMHKIL_02739 7.59e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_02740 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
FMFMHKIL_02741 1.82e-137 yrkC - - G - - - Cupin domain
FMFMHKIL_02742 4.38e-52 yrkD - - S - - - protein conserved in bacteria
FMFMHKIL_02743 7.44e-86 yrkE - - O - - - DsrE/DsrF/DrsH-like family
FMFMHKIL_02744 2.28e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
FMFMHKIL_02745 2.07e-263 yrkH - - P - - - Rhodanese Homology Domain
FMFMHKIL_02746 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
FMFMHKIL_02747 1.9e-149 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
FMFMHKIL_02748 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
FMFMHKIL_02749 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
FMFMHKIL_02750 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
FMFMHKIL_02751 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
FMFMHKIL_02752 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
FMFMHKIL_02753 7.32e-306 yrkQ - - T - - - Histidine kinase
FMFMHKIL_02754 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_02755 1.58e-122 xkdA - - E - - - IrrE N-terminal-like domain
FMFMHKIL_02756 8.73e-132 yqaC - - F - - - adenylate kinase activity
FMFMHKIL_02758 1.25e-74 - - - K - - - sequence-specific DNA binding
FMFMHKIL_02759 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
FMFMHKIL_02761 1.04e-133 - - - - - - - -
FMFMHKIL_02765 3.18e-213 yqaJ - - L - - - YqaJ-like viral recombinase domain
FMFMHKIL_02766 2.79e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
FMFMHKIL_02767 5.29e-156 yqaL - - L - - - DnaD domain protein
FMFMHKIL_02768 5.04e-207 yqaM - - L - - - IstB-like ATP binding protein
FMFMHKIL_02770 1.28e-93 rusA - - L - - - Endodeoxyribonuclease RusA
FMFMHKIL_02771 8.38e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
FMFMHKIL_02773 2.83e-99 yqaQ - - L - - - Transposase
FMFMHKIL_02775 7.73e-147 yqaS - - L - - - DNA packaging
FMFMHKIL_02776 2.69e-312 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
FMFMHKIL_02777 0.0 yqbA - - S - - - portal protein
FMFMHKIL_02778 1.79e-194 - - - S - - - Phage Mu protein F like protein
FMFMHKIL_02780 4.23e-158 yqbD - - L - - - Putative phage serine protease XkdF
FMFMHKIL_02781 8.83e-214 xkdG - - S - - - Phage capsid family
FMFMHKIL_02782 2.12e-60 - - - S - - - YqbF, hypothetical protein domain
FMFMHKIL_02783 1.43e-87 - - - S - - - Protein of unknown function (DUF3199)
FMFMHKIL_02784 9.68e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
FMFMHKIL_02785 1.79e-112 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
FMFMHKIL_02786 1.48e-98 yqbJ - - - - - - -
FMFMHKIL_02787 1.21e-34 - - - - - - - -
FMFMHKIL_02788 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
FMFMHKIL_02789 7.03e-98 xkdM - - S - - - Phage tail tube protein
FMFMHKIL_02791 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
FMFMHKIL_02792 0.0 xkdO - - L - - - Transglycosylase SLT domain
FMFMHKIL_02793 6.56e-156 xkdP - - S - - - Lysin motif
FMFMHKIL_02794 1.02e-231 xkdQ - - G - - - NLP P60 protein
FMFMHKIL_02795 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
FMFMHKIL_02796 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
FMFMHKIL_02797 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FMFMHKIL_02798 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
FMFMHKIL_02799 3e-54 - - - - - - - -
FMFMHKIL_02800 2.91e-283 - - - - - - - -
FMFMHKIL_02801 1.01e-73 xkdW - - S - - - XkdW protein
FMFMHKIL_02802 9.34e-33 - - - - - - - -
FMFMHKIL_02803 2.45e-213 xepA - - - - - - -
FMFMHKIL_02804 8.36e-89 - - - S - - - Bacteriophage holin family
FMFMHKIL_02805 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
FMFMHKIL_02807 5.4e-80 - - - - - - - -
FMFMHKIL_02809 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
FMFMHKIL_02810 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
FMFMHKIL_02813 1.14e-117 - - - S - - - Tetratricopeptide repeat
FMFMHKIL_02814 4.35e-53 - - - S - - - Spore coat protein Z
FMFMHKIL_02815 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
FMFMHKIL_02816 1.77e-61 - - - - - - - -
FMFMHKIL_02817 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
FMFMHKIL_02818 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
FMFMHKIL_02819 1.69e-142 - - - S - - - PepSY-associated TM region
FMFMHKIL_02820 9e-62 - - - S - - - PepSY-associated TM region
FMFMHKIL_02821 1.37e-30 - - - S - - - YtkA-like
FMFMHKIL_02822 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
FMFMHKIL_02823 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
FMFMHKIL_02824 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_02825 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
FMFMHKIL_02826 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
FMFMHKIL_02827 0.0 - - - L ko:K06400 - ko00000 Recombinase
FMFMHKIL_02828 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_02829 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
FMFMHKIL_02830 9.38e-171 - - - - - - - -
FMFMHKIL_02831 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
FMFMHKIL_02832 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
FMFMHKIL_02833 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
FMFMHKIL_02834 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
FMFMHKIL_02835 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
FMFMHKIL_02837 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
FMFMHKIL_02838 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
FMFMHKIL_02839 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FMFMHKIL_02840 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
FMFMHKIL_02841 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FMFMHKIL_02842 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
FMFMHKIL_02843 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FMFMHKIL_02844 9.8e-179 yqeM - - Q - - - Methyltransferase
FMFMHKIL_02845 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FMFMHKIL_02846 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
FMFMHKIL_02847 5.39e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
FMFMHKIL_02848 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
FMFMHKIL_02849 2.36e-22 - - - S - - - YqzM-like protein
FMFMHKIL_02850 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
FMFMHKIL_02851 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
FMFMHKIL_02852 1.39e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FMFMHKIL_02853 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
FMFMHKIL_02854 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
FMFMHKIL_02855 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FMFMHKIL_02856 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
FMFMHKIL_02857 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FMFMHKIL_02858 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FMFMHKIL_02859 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
FMFMHKIL_02860 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FMFMHKIL_02861 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
FMFMHKIL_02862 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FMFMHKIL_02863 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
FMFMHKIL_02864 2.04e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
FMFMHKIL_02865 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
FMFMHKIL_02866 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
FMFMHKIL_02867 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
FMFMHKIL_02868 8.78e-192 yqfA - - S - - - UPF0365 protein
FMFMHKIL_02869 3.13e-79 yqfB - - - - - - -
FMFMHKIL_02870 2.07e-60 yqfC - - S - - - sporulation protein YqfC
FMFMHKIL_02871 1.21e-241 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
FMFMHKIL_02872 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
FMFMHKIL_02874 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
FMFMHKIL_02875 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FMFMHKIL_02876 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
FMFMHKIL_02877 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FMFMHKIL_02878 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FMFMHKIL_02879 5.29e-27 - - - S - - - YqzL-like protein
FMFMHKIL_02880 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
FMFMHKIL_02881 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
FMFMHKIL_02882 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
FMFMHKIL_02883 3.29e-144 ccpN - - K - - - CBS domain
FMFMHKIL_02884 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FMFMHKIL_02885 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
FMFMHKIL_02886 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FMFMHKIL_02887 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FMFMHKIL_02888 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
FMFMHKIL_02889 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
FMFMHKIL_02890 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FMFMHKIL_02891 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FMFMHKIL_02892 4.89e-58 yqfQ - - S - - - YqfQ-like protein
FMFMHKIL_02893 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FMFMHKIL_02894 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FMFMHKIL_02895 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
FMFMHKIL_02896 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
FMFMHKIL_02897 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
FMFMHKIL_02898 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
FMFMHKIL_02899 2.04e-81 yqfX - - S - - - membrane
FMFMHKIL_02900 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FMFMHKIL_02901 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
FMFMHKIL_02902 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
FMFMHKIL_02903 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
FMFMHKIL_02904 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
FMFMHKIL_02905 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
FMFMHKIL_02906 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
FMFMHKIL_02907 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
FMFMHKIL_02908 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
FMFMHKIL_02909 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
FMFMHKIL_02910 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FMFMHKIL_02911 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FMFMHKIL_02912 1.09e-93 yqzC - - S - - - YceG-like family
FMFMHKIL_02913 2.81e-67 yqzD - - - - - - -
FMFMHKIL_02915 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
FMFMHKIL_02916 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FMFMHKIL_02917 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FMFMHKIL_02918 3.38e-14 yqgO - - - - - - -
FMFMHKIL_02919 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
FMFMHKIL_02920 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
FMFMHKIL_02921 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
FMFMHKIL_02922 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
FMFMHKIL_02923 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
FMFMHKIL_02924 2.69e-256 yqgU - - - - - - -
FMFMHKIL_02925 7.34e-66 yqgV - - S - - - Thiamine-binding protein
FMFMHKIL_02926 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
FMFMHKIL_02927 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
FMFMHKIL_02928 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
FMFMHKIL_02929 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
FMFMHKIL_02931 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FMFMHKIL_02932 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
FMFMHKIL_02933 1.51e-233 yqxL - - P - - - Mg2 transporter protein
FMFMHKIL_02934 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
FMFMHKIL_02936 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FMFMHKIL_02937 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
FMFMHKIL_02938 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
FMFMHKIL_02939 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
FMFMHKIL_02940 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
FMFMHKIL_02941 9.65e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
FMFMHKIL_02942 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
FMFMHKIL_02943 3.33e-35 yqzE - - S - - - YqzE-like protein
FMFMHKIL_02944 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
FMFMHKIL_02945 8e-156 yqxM - - - ko:K19433 - ko00000 -
FMFMHKIL_02946 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
FMFMHKIL_02947 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
FMFMHKIL_02948 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
FMFMHKIL_02949 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
FMFMHKIL_02950 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
FMFMHKIL_02951 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
FMFMHKIL_02952 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
FMFMHKIL_02953 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FMFMHKIL_02954 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FMFMHKIL_02955 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
FMFMHKIL_02956 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
FMFMHKIL_02957 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
FMFMHKIL_02958 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
FMFMHKIL_02959 5.18e-81 yqhP - - - - - - -
FMFMHKIL_02960 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
FMFMHKIL_02961 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
FMFMHKIL_02962 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
FMFMHKIL_02963 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
FMFMHKIL_02964 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FMFMHKIL_02965 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
FMFMHKIL_02966 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
FMFMHKIL_02967 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
FMFMHKIL_02968 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
FMFMHKIL_02969 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
FMFMHKIL_02970 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
FMFMHKIL_02971 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
FMFMHKIL_02972 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
FMFMHKIL_02973 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
FMFMHKIL_02974 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FMFMHKIL_02975 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
FMFMHKIL_02976 1.65e-88 yqhY - - S - - - protein conserved in bacteria
FMFMHKIL_02977 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FMFMHKIL_02978 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FMFMHKIL_02979 2.05e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FMFMHKIL_02980 3.81e-50 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FMFMHKIL_02981 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
FMFMHKIL_02982 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FMFMHKIL_02983 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
FMFMHKIL_02984 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
FMFMHKIL_02985 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
FMFMHKIL_02986 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
FMFMHKIL_02987 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
FMFMHKIL_02989 2.81e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
FMFMHKIL_02990 4.74e-37 - - - - - - - -
FMFMHKIL_02991 1.14e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
FMFMHKIL_02992 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
FMFMHKIL_02993 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
FMFMHKIL_02994 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
FMFMHKIL_02995 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
FMFMHKIL_02996 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
FMFMHKIL_02997 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
FMFMHKIL_02998 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FMFMHKIL_02999 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
FMFMHKIL_03000 0.0 bkdR - - KT - - - Transcriptional regulator
FMFMHKIL_03001 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
FMFMHKIL_03002 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
FMFMHKIL_03003 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
FMFMHKIL_03004 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FMFMHKIL_03005 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FMFMHKIL_03006 1.98e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FMFMHKIL_03007 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FMFMHKIL_03008 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
FMFMHKIL_03009 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_03010 4.06e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FMFMHKIL_03011 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
FMFMHKIL_03012 6.81e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
FMFMHKIL_03013 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
FMFMHKIL_03014 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
FMFMHKIL_03015 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
FMFMHKIL_03016 2.41e-128 yqjB - - S - - - protein conserved in bacteria
FMFMHKIL_03018 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
FMFMHKIL_03019 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FMFMHKIL_03020 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
FMFMHKIL_03021 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
FMFMHKIL_03022 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FMFMHKIL_03023 1.77e-32 yqzJ - - - - - - -
FMFMHKIL_03024 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FMFMHKIL_03025 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FMFMHKIL_03026 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FMFMHKIL_03027 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FMFMHKIL_03028 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FMFMHKIL_03029 1.29e-186 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FMFMHKIL_03030 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
FMFMHKIL_03031 0.0 rocB - - E - - - arginine degradation protein
FMFMHKIL_03032 2.56e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FMFMHKIL_03033 1.09e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
FMFMHKIL_03034 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_03035 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
FMFMHKIL_03036 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
FMFMHKIL_03037 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_03039 7.01e-286 yqjV - - G - - - Major Facilitator Superfamily
FMFMHKIL_03041 4.7e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FMFMHKIL_03042 9.27e-66 yqiX - - S - - - YolD-like protein
FMFMHKIL_03043 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
FMFMHKIL_03044 2.25e-71 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
FMFMHKIL_03045 3.37e-250 yqkA - - K - - - GrpB protein
FMFMHKIL_03046 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
FMFMHKIL_03047 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
FMFMHKIL_03048 7.12e-226 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
FMFMHKIL_03049 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
FMFMHKIL_03050 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
FMFMHKIL_03051 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
FMFMHKIL_03052 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
FMFMHKIL_03053 2.62e-283 yqxK - - L - - - DNA helicase
FMFMHKIL_03054 3.18e-77 ansR - - K - - - Transcriptional regulator
FMFMHKIL_03055 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
FMFMHKIL_03056 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
FMFMHKIL_03057 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
FMFMHKIL_03058 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
FMFMHKIL_03059 3.73e-44 yqkK - - - - - - -
FMFMHKIL_03060 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
FMFMHKIL_03061 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
FMFMHKIL_03062 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
FMFMHKIL_03063 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
FMFMHKIL_03064 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
FMFMHKIL_03065 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FMFMHKIL_03066 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FMFMHKIL_03067 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
FMFMHKIL_03068 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
FMFMHKIL_03069 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_03070 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
FMFMHKIL_03071 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
FMFMHKIL_03072 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
FMFMHKIL_03073 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
FMFMHKIL_03074 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
FMFMHKIL_03075 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
FMFMHKIL_03076 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
FMFMHKIL_03077 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FMFMHKIL_03078 2.67e-193 ypuA - - S - - - Secreted protein
FMFMHKIL_03079 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FMFMHKIL_03081 1.61e-16 - - - S - - - SNARE associated Golgi protein
FMFMHKIL_03082 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
FMFMHKIL_03083 4.99e-127 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FMFMHKIL_03084 2.96e-72 ypuD - - - - - - -
FMFMHKIL_03085 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FMFMHKIL_03086 2.05e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
FMFMHKIL_03087 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FMFMHKIL_03088 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FMFMHKIL_03089 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMFMHKIL_03090 3.43e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
FMFMHKIL_03091 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FMFMHKIL_03092 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FMFMHKIL_03093 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
FMFMHKIL_03094 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FMFMHKIL_03095 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
FMFMHKIL_03096 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
FMFMHKIL_03097 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FMFMHKIL_03098 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
FMFMHKIL_03099 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
FMFMHKIL_03100 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
FMFMHKIL_03101 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_03102 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_03103 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
FMFMHKIL_03104 1.49e-254 rsiX - - - - - - -
FMFMHKIL_03105 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FMFMHKIL_03106 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMFMHKIL_03107 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FMFMHKIL_03108 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
FMFMHKIL_03109 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
FMFMHKIL_03110 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
FMFMHKIL_03111 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
FMFMHKIL_03112 4.22e-139 ypbE - - M - - - Lysin motif
FMFMHKIL_03113 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
FMFMHKIL_03114 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
FMFMHKIL_03115 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FMFMHKIL_03116 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
FMFMHKIL_03117 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
FMFMHKIL_03118 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
FMFMHKIL_03119 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
FMFMHKIL_03120 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
FMFMHKIL_03121 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
FMFMHKIL_03122 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
FMFMHKIL_03123 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
FMFMHKIL_03124 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
FMFMHKIL_03125 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FMFMHKIL_03126 5.6e-12 - - - S - - - YpzI-like protein
FMFMHKIL_03127 3.87e-134 yphA - - - - - - -
FMFMHKIL_03130 4.18e-14 - - - - - - - -
FMFMHKIL_03133 1.04e-42 - - - S - - - Terminase
FMFMHKIL_03134 6.85e-103 - - - L - - - phage terminase small subunit
FMFMHKIL_03135 1.89e-63 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
FMFMHKIL_03140 4.25e-25 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
FMFMHKIL_03141 1.4e-86 - - - S - - - regulation of transcription, DNA-dependent
FMFMHKIL_03142 1.82e-31 - - - S - - - FRG
FMFMHKIL_03143 4.9e-66 - - - M - - - ArpU family transcriptional regulator
FMFMHKIL_03146 3.5e-30 - - - - - - - -
FMFMHKIL_03147 9.44e-127 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
FMFMHKIL_03148 4.61e-47 - - - L - - - Arm DNA-binding domain
FMFMHKIL_03149 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
FMFMHKIL_03150 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
FMFMHKIL_03151 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
FMFMHKIL_03152 2.12e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FMFMHKIL_03153 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
FMFMHKIL_03154 2e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
FMFMHKIL_03155 2.24e-141 - - - - - - - -
FMFMHKIL_03156 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMFMHKIL_03157 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMFMHKIL_03158 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
FMFMHKIL_03159 1.2e-30 ymzA - - - - - - -
FMFMHKIL_03160 1.63e-31 - - - - - - - -
FMFMHKIL_03161 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
FMFMHKIL_03162 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FMFMHKIL_03163 5.41e-76 ymaF - - S - - - YmaF family
FMFMHKIL_03165 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
FMFMHKIL_03166 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
FMFMHKIL_03167 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
FMFMHKIL_03168 3.96e-163 ymaC - - S - - - Replication protein
FMFMHKIL_03170 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
FMFMHKIL_03171 7.65e-207 - - - S - - - Metallo-beta-lactamase superfamily
FMFMHKIL_03172 9.39e-80 ymzB - - - - - - -
FMFMHKIL_03173 9.72e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
FMFMHKIL_03174 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
FMFMHKIL_03175 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
FMFMHKIL_03176 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
FMFMHKIL_03177 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
FMFMHKIL_03178 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
FMFMHKIL_03179 1.75e-173 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
FMFMHKIL_03180 2.04e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
FMFMHKIL_03181 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
FMFMHKIL_03182 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FMFMHKIL_03183 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
FMFMHKIL_03184 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
FMFMHKIL_03185 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
FMFMHKIL_03187 1.78e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
FMFMHKIL_03188 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
FMFMHKIL_03189 3.43e-140 pksA - - K - - - Transcriptional regulator
FMFMHKIL_03190 1.13e-126 ymcC - - S - - - Membrane
FMFMHKIL_03192 2.93e-92 - - - S - - - Regulatory protein YrvL
FMFMHKIL_03193 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FMFMHKIL_03194 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FMFMHKIL_03195 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
FMFMHKIL_03196 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
FMFMHKIL_03197 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FMFMHKIL_03198 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FMFMHKIL_03199 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
FMFMHKIL_03200 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
FMFMHKIL_03201 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
FMFMHKIL_03202 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
FMFMHKIL_03203 1.95e-254 pbpX - - V - - - Beta-lactamase
FMFMHKIL_03204 2.26e-118 - - - M - - - Glycosyltransferase like family
FMFMHKIL_03205 7.89e-154 - - - H - - - Methionine biosynthesis protein MetW
FMFMHKIL_03206 1.03e-240 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_03207 1.56e-274 - - - H - - - N-terminal domain of galactosyltransferase
FMFMHKIL_03209 3.38e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
FMFMHKIL_03211 3.45e-90 - - - S - - - CAAX protease self-immunity
FMFMHKIL_03212 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
FMFMHKIL_03213 2.79e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
FMFMHKIL_03214 1.1e-142 - - - S - - - Domain of unknown function (DUF3885)
FMFMHKIL_03215 1.14e-61 ynaF - - - - - - -
FMFMHKIL_03218 1.76e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
FMFMHKIL_03219 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
FMFMHKIL_03220 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
FMFMHKIL_03221 5.85e-274 xylR - - GK - - - ROK family
FMFMHKIL_03222 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
FMFMHKIL_03223 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
FMFMHKIL_03224 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
FMFMHKIL_03225 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMFMHKIL_03226 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FMFMHKIL_03227 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
FMFMHKIL_03230 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
FMFMHKIL_03231 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
FMFMHKIL_03232 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FMFMHKIL_03233 4.94e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
FMFMHKIL_03234 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
FMFMHKIL_03235 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FMFMHKIL_03236 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FMFMHKIL_03237 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_03238 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_03239 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
FMFMHKIL_03240 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
FMFMHKIL_03241 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
FMFMHKIL_03242 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
FMFMHKIL_03244 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
FMFMHKIL_03245 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
FMFMHKIL_03246 4.79e-160 - - - - - - - -
FMFMHKIL_03247 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FMFMHKIL_03248 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
FMFMHKIL_03249 4.31e-157 ydhC - - K - - - FCD
FMFMHKIL_03250 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
FMFMHKIL_03251 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
FMFMHKIL_03252 6.63e-90 - - - K - - - Winged helix DNA-binding domain
FMFMHKIL_03253 9.12e-147 ydgI - - C - - - nitroreductase
FMFMHKIL_03254 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
FMFMHKIL_03255 8.04e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_03256 2.32e-115 - - - S - - - DinB family
FMFMHKIL_03257 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_03258 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
FMFMHKIL_03259 2.46e-68 yycN - - K - - - Acetyltransferase
FMFMHKIL_03260 1.93e-68 - - - S - - - DoxX-like family
FMFMHKIL_03261 4.04e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
FMFMHKIL_03262 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
FMFMHKIL_03263 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
FMFMHKIL_03264 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
FMFMHKIL_03265 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
FMFMHKIL_03266 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
FMFMHKIL_03268 5.33e-39 - - - - - - - -
FMFMHKIL_03269 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
FMFMHKIL_03270 7.63e-74 ydfQ - - CO - - - Thioredoxin
FMFMHKIL_03271 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
FMFMHKIL_03272 1.51e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
FMFMHKIL_03273 2.83e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
FMFMHKIL_03274 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FMFMHKIL_03275 1.18e-186 - - - K - - - Bacterial transcription activator, effector binding domain
FMFMHKIL_03276 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
FMFMHKIL_03277 3.87e-13 - - - S - - - Alpha/beta hydrolase family
FMFMHKIL_03278 5.32e-186 - - - S - - - Alpha/beta hydrolase family
FMFMHKIL_03279 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
FMFMHKIL_03280 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_03281 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_03283 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FMFMHKIL_03284 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
FMFMHKIL_03285 2.34e-148 ydfE - - S - - - Flavin reductase like domain
FMFMHKIL_03286 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_03287 9.56e-195 - - - EG - - - EamA-like transporter family
FMFMHKIL_03288 2.59e-187 - - - J - - - GNAT acetyltransferase
FMFMHKIL_03289 9.69e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FMFMHKIL_03290 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
FMFMHKIL_03291 4.73e-133 ydeS - - K - - - Transcriptional regulator
FMFMHKIL_03292 1.13e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
FMFMHKIL_03293 2.36e-143 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
FMFMHKIL_03294 2.92e-90 ydeP - - K - - - Transcriptional regulator
FMFMHKIL_03295 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
FMFMHKIL_03296 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
FMFMHKIL_03297 2.31e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
FMFMHKIL_03298 3.54e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
FMFMHKIL_03299 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_03300 1.49e-193 ydeK - - EG - - - -transporter
FMFMHKIL_03302 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
FMFMHKIL_03303 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
FMFMHKIL_03304 4.01e-92 - - - S - - - SNARE associated Golgi protein
FMFMHKIL_03305 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
FMFMHKIL_03306 5.54e-146 - - - T - - - Transcriptional regulator
FMFMHKIL_03307 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
FMFMHKIL_03308 2.46e-140 - - - - - - - -
FMFMHKIL_03309 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
FMFMHKIL_03310 9.2e-70 ydeH - - - - - - -
FMFMHKIL_03311 3.8e-277 ydeG - - EGP - - - Major facilitator superfamily
FMFMHKIL_03312 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_03313 4.94e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
FMFMHKIL_03314 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FMFMHKIL_03315 2.18e-213 - - - K - - - AraC-like ligand binding domain
FMFMHKIL_03316 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FMFMHKIL_03317 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
FMFMHKIL_03318 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
FMFMHKIL_03319 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
FMFMHKIL_03323 6e-53 - - - - - - - -
FMFMHKIL_03324 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
FMFMHKIL_03327 7.24e-08 - - - S - - - Putative amidase domain
FMFMHKIL_03330 9.05e-56 - - - L - - - HNH nucleases
FMFMHKIL_03331 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
FMFMHKIL_03332 3.85e-24 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
FMFMHKIL_03333 2.85e-58 - - - - - - - -
FMFMHKIL_03334 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
FMFMHKIL_03342 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
FMFMHKIL_03343 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
FMFMHKIL_03344 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_03345 1.32e-106 ydcG - - S - - - EVE domain
FMFMHKIL_03349 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
FMFMHKIL_03350 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_03351 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
FMFMHKIL_03352 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
FMFMHKIL_03353 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
FMFMHKIL_03354 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
FMFMHKIL_03355 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
FMFMHKIL_03356 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
FMFMHKIL_03357 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
FMFMHKIL_03358 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
FMFMHKIL_03359 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FMFMHKIL_03360 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
FMFMHKIL_03361 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FMFMHKIL_03362 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
FMFMHKIL_03363 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
FMFMHKIL_03364 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
FMFMHKIL_03365 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FMFMHKIL_03366 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FMFMHKIL_03367 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
FMFMHKIL_03368 4.19e-75 ydbP - - CO - - - Thioredoxin
FMFMHKIL_03369 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FMFMHKIL_03371 1.49e-26 - - - S - - - Fur-regulated basic protein B
FMFMHKIL_03372 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
FMFMHKIL_03373 7.67e-69 ydbL - - - - - - -
FMFMHKIL_03374 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FMFMHKIL_03375 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_03376 1.32e-230 ydbI - - S - - - AI-2E family transporter
FMFMHKIL_03377 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FMFMHKIL_03378 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
FMFMHKIL_03379 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
FMFMHKIL_03380 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
FMFMHKIL_03381 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
FMFMHKIL_03382 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
FMFMHKIL_03383 7.58e-79 ydbB - - G - - - Cupin domain
FMFMHKIL_03384 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
FMFMHKIL_03385 7.14e-189 ydbA - - P - - - EcsC protein family
FMFMHKIL_03386 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
FMFMHKIL_03387 1.67e-42 ydaS - - S - - - membrane
FMFMHKIL_03388 3.2e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
FMFMHKIL_03389 6.14e-53 - - - - - - - -
FMFMHKIL_03391 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
FMFMHKIL_03392 2.54e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
FMFMHKIL_03393 0.0 ydaO - - E - - - amino acid
FMFMHKIL_03394 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
FMFMHKIL_03395 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
FMFMHKIL_03396 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
FMFMHKIL_03397 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
FMFMHKIL_03398 1.11e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
FMFMHKIL_03399 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FMFMHKIL_03400 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
FMFMHKIL_03401 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
FMFMHKIL_03402 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FMFMHKIL_03403 3.04e-100 ydaG - - S - - - general stress protein
FMFMHKIL_03404 6.34e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FMFMHKIL_03405 1.12e-124 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
FMFMHKIL_03406 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_03407 1e-127 ydaC - - Q - - - Methyltransferase domain
FMFMHKIL_03408 0.0 ydaB - - IQ - - - acyl-CoA ligase
FMFMHKIL_03409 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
FMFMHKIL_03410 8.6e-220 ycsN - - S - - - Oxidoreductase
FMFMHKIL_03411 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
FMFMHKIL_03412 7.67e-66 yczJ - - S - - - biosynthesis
FMFMHKIL_03414 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
FMFMHKIL_03415 3.8e-171 kipR - - K - - - Transcriptional regulator
FMFMHKIL_03416 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
FMFMHKIL_03417 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
FMFMHKIL_03418 1.68e-144 ycsI - - S - - - Belongs to the D-glutamate cyclase family
FMFMHKIL_03419 7.45e-20 ycsI - - S - - - Belongs to the D-glutamate cyclase family
FMFMHKIL_03420 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
FMFMHKIL_03421 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
FMFMHKIL_03422 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
FMFMHKIL_03424 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
FMFMHKIL_03425 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
FMFMHKIL_03426 1.78e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FMFMHKIL_03428 5.62e-254 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
FMFMHKIL_03429 8.5e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
FMFMHKIL_03430 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
FMFMHKIL_03431 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
FMFMHKIL_03432 1.34e-74 - - - - - - - -
FMFMHKIL_03433 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
FMFMHKIL_03434 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
FMFMHKIL_03435 3.99e-134 ycnI - - S - - - protein conserved in bacteria
FMFMHKIL_03436 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_03437 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
FMFMHKIL_03438 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FMFMHKIL_03439 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMFMHKIL_03440 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FMFMHKIL_03441 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
FMFMHKIL_03442 1.68e-60 ycnE - - S - - - Monooxygenase
FMFMHKIL_03443 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
FMFMHKIL_03444 5.87e-198 ycnC - - K - - - Transcriptional regulator
FMFMHKIL_03445 0.0 ycnB - - EGP - - - the major facilitator superfamily
FMFMHKIL_03446 1.18e-96 - - - V - - - Restriction endonuclease
FMFMHKIL_03447 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
FMFMHKIL_03448 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_03449 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03450 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03451 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
FMFMHKIL_03452 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
FMFMHKIL_03454 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
FMFMHKIL_03455 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
FMFMHKIL_03456 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FMFMHKIL_03457 2.27e-279 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
FMFMHKIL_03458 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
FMFMHKIL_03459 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
FMFMHKIL_03460 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
FMFMHKIL_03461 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
FMFMHKIL_03463 0.0 yclG - - M - - - Pectate lyase superfamily protein
FMFMHKIL_03464 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
FMFMHKIL_03465 2.15e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
FMFMHKIL_03466 2.82e-105 yclD - - - - - - -
FMFMHKIL_03467 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
FMFMHKIL_03468 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
FMFMHKIL_03469 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
FMFMHKIL_03470 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
FMFMHKIL_03471 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
FMFMHKIL_03472 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
FMFMHKIL_03473 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
FMFMHKIL_03474 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
FMFMHKIL_03475 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
FMFMHKIL_03476 0.0 ycxD - - K - - - GntR family transcriptional regulator
FMFMHKIL_03477 7.69e-204 ycxC - - EG - - - EamA-like transporter family
FMFMHKIL_03478 2.87e-120 - - - S - - - YcxB-like protein
FMFMHKIL_03479 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
FMFMHKIL_03480 2.71e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
FMFMHKIL_03481 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
FMFMHKIL_03482 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_03483 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
FMFMHKIL_03484 3.95e-72 ygzB - - S - - - UPF0295 protein
FMFMHKIL_03485 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
FMFMHKIL_03486 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
FMFMHKIL_03487 1.33e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
FMFMHKIL_03488 1.87e-238 ygaE - - S - - - Membrane
FMFMHKIL_03489 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
FMFMHKIL_03490 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
FMFMHKIL_03491 1.88e-63 ygaB - - S - - - YgaB-like protein
FMFMHKIL_03492 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
FMFMHKIL_03493 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMFMHKIL_03494 1.73e-48 yfhS - - - - - - -
FMFMHKIL_03495 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
FMFMHKIL_03496 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
FMFMHKIL_03497 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
FMFMHKIL_03498 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
FMFMHKIL_03499 3.93e-218 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
FMFMHKIL_03500 4.74e-62 yfhL - - S - - - SdpI/YhfL protein family
FMFMHKIL_03501 1.7e-117 yfhK - - T - - - Bacterial SH3 domain homologues
FMFMHKIL_03502 8.95e-60 yfhJ - - S - - - WVELL protein
FMFMHKIL_03503 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
FMFMHKIL_03504 3.47e-268 yfhI - - EGP - - - -transporter
FMFMHKIL_03505 4.8e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
FMFMHKIL_03506 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
FMFMHKIL_03507 3.11e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
FMFMHKIL_03509 8.86e-35 yfhD - - S - - - YfhD-like protein
FMFMHKIL_03510 2.87e-138 yfhC - - C - - - nitroreductase
FMFMHKIL_03511 7.61e-215 yfhB - - S - - - PhzF family
FMFMHKIL_03512 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03513 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03514 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
FMFMHKIL_03515 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FMFMHKIL_03516 2.11e-103 yfiV - - K - - - transcriptional
FMFMHKIL_03517 0.0 yfiU - - EGP - - - the major facilitator superfamily
FMFMHKIL_03518 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
FMFMHKIL_03519 8.95e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FMFMHKIL_03520 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
FMFMHKIL_03521 1.89e-128 padR - - K - - - transcriptional
FMFMHKIL_03522 3.84e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
FMFMHKIL_03523 1.46e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
FMFMHKIL_03524 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMFMHKIL_03525 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
FMFMHKIL_03526 1.98e-271 baeS - - T - - - Histidine kinase
FMFMHKIL_03528 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
FMFMHKIL_03529 3.34e-83 yfiD3 - - S - - - DoxX
FMFMHKIL_03530 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
FMFMHKIL_03531 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
FMFMHKIL_03532 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
FMFMHKIL_03533 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_03534 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
FMFMHKIL_03535 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FMFMHKIL_03536 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
FMFMHKIL_03537 6.91e-241 yfjB - - - - - - -
FMFMHKIL_03538 3.83e-161 yfjC - - - - - - -
FMFMHKIL_03539 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
FMFMHKIL_03540 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
FMFMHKIL_03541 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
FMFMHKIL_03542 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
FMFMHKIL_03543 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FMFMHKIL_03544 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FMFMHKIL_03545 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FMFMHKIL_03546 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FMFMHKIL_03547 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
FMFMHKIL_03548 3.47e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FMFMHKIL_03549 3.04e-59 - - - S - - - YfzA-like protein
FMFMHKIL_03550 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FMFMHKIL_03551 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FMFMHKIL_03552 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
FMFMHKIL_03553 5.16e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
FMFMHKIL_03554 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
FMFMHKIL_03555 3.26e-36 yfjT - - - - - - -
FMFMHKIL_03556 7.17e-283 yfkA - - S - - - YfkB-like domain
FMFMHKIL_03557 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
FMFMHKIL_03558 3.69e-189 yfkD - - S - - - YfkD-like protein
FMFMHKIL_03559 1.9e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
FMFMHKIL_03560 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_03561 1.64e-12 - - - - - - - -
FMFMHKIL_03562 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
FMFMHKIL_03563 2.53e-67 yfkI - - S - - - gas vesicle protein
FMFMHKIL_03564 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FMFMHKIL_03565 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
FMFMHKIL_03566 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_03567 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
FMFMHKIL_03568 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
FMFMHKIL_03569 5.27e-161 frp - - C - - - nitroreductase
FMFMHKIL_03570 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
FMFMHKIL_03571 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
FMFMHKIL_03572 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMFMHKIL_03573 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
FMFMHKIL_03574 9.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
FMFMHKIL_03576 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
FMFMHKIL_03577 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
FMFMHKIL_03578 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
FMFMHKIL_03579 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
FMFMHKIL_03580 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
FMFMHKIL_03581 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
FMFMHKIL_03582 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
FMFMHKIL_03583 9.81e-27 yflI - - - - - - -
FMFMHKIL_03584 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
FMFMHKIL_03585 5.91e-158 yflK - - S - - - protein conserved in bacteria
FMFMHKIL_03586 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
FMFMHKIL_03587 1.37e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FMFMHKIL_03588 2.94e-193 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
FMFMHKIL_03589 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
FMFMHKIL_03590 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
FMFMHKIL_03591 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
FMFMHKIL_03592 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
FMFMHKIL_03593 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
FMFMHKIL_03594 4.06e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
FMFMHKIL_03595 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
FMFMHKIL_03596 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
FMFMHKIL_03597 2.76e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
FMFMHKIL_03598 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03599 4.94e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMFMHKIL_03600 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
FMFMHKIL_03601 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
FMFMHKIL_03602 1.72e-268 - - - G - - - Major Facilitator Superfamily
FMFMHKIL_03603 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
FMFMHKIL_03604 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
FMFMHKIL_03605 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
FMFMHKIL_03606 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FMFMHKIL_03607 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
FMFMHKIL_03608 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
FMFMHKIL_03609 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
FMFMHKIL_03610 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FMFMHKIL_03611 5.14e-161 yfmS - - NT - - - chemotaxis protein
FMFMHKIL_03612 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FMFMHKIL_03613 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
FMFMHKIL_03614 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
FMFMHKIL_03615 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_03616 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
FMFMHKIL_03617 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
FMFMHKIL_03618 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
FMFMHKIL_03619 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
FMFMHKIL_03620 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
FMFMHKIL_03621 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
FMFMHKIL_03622 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
FMFMHKIL_03623 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
FMFMHKIL_03624 2.57e-171 - - - M - - - Membrane
FMFMHKIL_03625 1.78e-265 yetM - - CH - - - FAD binding domain
FMFMHKIL_03626 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMFMHKIL_03627 2.1e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
FMFMHKIL_03628 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
FMFMHKIL_03629 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FMFMHKIL_03630 9.79e-45 - - - - - - - -
FMFMHKIL_03631 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMFMHKIL_03632 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
FMFMHKIL_03633 1.49e-156 yetF - - S - - - membrane
FMFMHKIL_03634 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
FMFMHKIL_03635 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_03636 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
FMFMHKIL_03637 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
FMFMHKIL_03638 0.0 yetA - - - - - - -
FMFMHKIL_03639 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
FMFMHKIL_03640 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
FMFMHKIL_03641 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
FMFMHKIL_03642 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
FMFMHKIL_03643 7.78e-143 - - - S - - - Protein of unknown function, DUF624
FMFMHKIL_03644 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
FMFMHKIL_03645 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
FMFMHKIL_03646 0.0 yesS - - K - - - Transcriptional regulator
FMFMHKIL_03647 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
FMFMHKIL_03648 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_03649 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMFMHKIL_03650 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
FMFMHKIL_03651 1.89e-255 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
FMFMHKIL_03652 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMFMHKIL_03653 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
FMFMHKIL_03654 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
FMFMHKIL_03655 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
FMFMHKIL_03656 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
FMFMHKIL_03657 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
FMFMHKIL_03658 1.23e-195 yesF - - GM - - - NAD(P)H-binding
FMFMHKIL_03659 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
FMFMHKIL_03660 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_03662 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
FMFMHKIL_03664 1.42e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
FMFMHKIL_03665 2.32e-235 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
FMFMHKIL_03666 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
FMFMHKIL_03667 1.09e-73 - - - S - - - Protein of unknown function, DUF600
FMFMHKIL_03668 8.48e-105 - - - S - - - Protein of unknown function, DUF600
FMFMHKIL_03670 4.5e-41 - - - S - - - Colicin immunity protein / pyocin immunity protein
FMFMHKIL_03672 4.53e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
FMFMHKIL_03675 6.7e-95 - - - V - - - Type I restriction modification DNA specificity domain
FMFMHKIL_03676 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system methyltransferase subunit()
FMFMHKIL_03677 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FMFMHKIL_03678 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FMFMHKIL_03679 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FMFMHKIL_03680 2.08e-190 yerO - - K - - - Transcriptional regulator
FMFMHKIL_03681 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMFMHKIL_03682 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FMFMHKIL_03683 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMFMHKIL_03684 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FMFMHKIL_03685 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
FMFMHKIL_03686 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
FMFMHKIL_03687 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
FMFMHKIL_03688 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FMFMHKIL_03689 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
FMFMHKIL_03690 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FMFMHKIL_03692 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
FMFMHKIL_03693 7.62e-68 yerC - - S - - - protein conserved in bacteria
FMFMHKIL_03694 9.18e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
FMFMHKIL_03695 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
FMFMHKIL_03696 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
FMFMHKIL_03697 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
FMFMHKIL_03698 1.29e-94 - - - K - - - helix_turn_helix ASNC type
FMFMHKIL_03699 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
FMFMHKIL_03700 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
FMFMHKIL_03701 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FMFMHKIL_03702 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
FMFMHKIL_03703 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FMFMHKIL_03704 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMFMHKIL_03705 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMFMHKIL_03706 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMFMHKIL_03707 7.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
FMFMHKIL_03708 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FMFMHKIL_03709 4.83e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FMFMHKIL_03710 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FMFMHKIL_03711 3.13e-38 yebG - - S - - - NETI protein
FMFMHKIL_03712 2.66e-120 yebE - - S - - - UPF0316 protein
FMFMHKIL_03714 2.78e-163 yebC - - M - - - Membrane
FMFMHKIL_03715 2.81e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
FMFMHKIL_03716 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
FMFMHKIL_03717 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
FMFMHKIL_03718 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
FMFMHKIL_03719 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
FMFMHKIL_03720 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FMFMHKIL_03721 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
FMFMHKIL_03722 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
FMFMHKIL_03723 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
FMFMHKIL_03724 3.21e-205 - - - I - - - Alpha/beta hydrolase family
FMFMHKIL_03725 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
FMFMHKIL_03727 1.27e-204 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
FMFMHKIL_03728 1.79e-84 ydjM - - M - - - Lytic transglycolase
FMFMHKIL_03729 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
FMFMHKIL_03730 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMFMHKIL_03731 1.37e-248 - - - S - - - Ion transport 2 domain protein
FMFMHKIL_03732 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
FMFMHKIL_03733 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
FMFMHKIL_03734 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FMFMHKIL_03735 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
FMFMHKIL_03736 7.03e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
FMFMHKIL_03737 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
FMFMHKIL_03738 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
FMFMHKIL_03739 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
FMFMHKIL_03740 8.95e-31 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
FMFMHKIL_03741 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
FMFMHKIL_03744 7.05e-293 - - - S - - - Bacterial EndoU nuclease
FMFMHKIL_03745 1.93e-53 - - - - - - - -
FMFMHKIL_03747 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FMFMHKIL_03748 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FMFMHKIL_03749 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
FMFMHKIL_03750 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
FMFMHKIL_03751 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FMFMHKIL_03752 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FMFMHKIL_03753 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FMFMHKIL_03754 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
FMFMHKIL_03755 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
FMFMHKIL_03756 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FMFMHKIL_03757 2.34e-107 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
FMFMHKIL_03758 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
FMFMHKIL_03759 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
FMFMHKIL_03760 1.9e-231 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FMFMHKIL_03763 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_03765 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_03766 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
FMFMHKIL_03767 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
FMFMHKIL_03768 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
FMFMHKIL_03769 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
FMFMHKIL_03770 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
FMFMHKIL_03771 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FMFMHKIL_03772 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
FMFMHKIL_03773 1.19e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
FMFMHKIL_03774 3.89e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
FMFMHKIL_03775 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
FMFMHKIL_03776 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FMFMHKIL_03777 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
FMFMHKIL_03778 2.01e-134 yngC - - S - - - membrane-associated protein
FMFMHKIL_03779 7.53e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
FMFMHKIL_03780 4.06e-102 yngA - - S - - - membrane
FMFMHKIL_03781 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
FMFMHKIL_03782 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
FMFMHKIL_03784 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
FMFMHKIL_03785 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
FMFMHKIL_03786 1.06e-75 ynfC - - - - - - -
FMFMHKIL_03787 1.82e-18 - - - - - - - -
FMFMHKIL_03788 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FMFMHKIL_03789 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FMFMHKIL_03790 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
FMFMHKIL_03791 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FMFMHKIL_03792 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
FMFMHKIL_03793 2.32e-71 yneQ - - - - - - -
FMFMHKIL_03794 1.64e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
FMFMHKIL_03795 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
FMFMHKIL_03797 9.26e-10 - - - S - - - Fur-regulated basic protein B
FMFMHKIL_03798 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FMFMHKIL_03799 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FMFMHKIL_03800 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
FMFMHKIL_03801 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
FMFMHKIL_03802 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
FMFMHKIL_03803 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
FMFMHKIL_03804 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
FMFMHKIL_03805 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
FMFMHKIL_03806 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
FMFMHKIL_03807 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
FMFMHKIL_03808 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
FMFMHKIL_03809 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
FMFMHKIL_03810 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FMFMHKIL_03811 1.15e-43 ynzC - - S - - - UPF0291 protein
FMFMHKIL_03812 2.29e-144 yneB - - L - - - resolvase
FMFMHKIL_03813 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
FMFMHKIL_03814 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FMFMHKIL_03815 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
FMFMHKIL_03816 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
FMFMHKIL_03817 3.26e-175 yndL - - S - - - Replication protein
FMFMHKIL_03819 0.0 yndJ - - S - - - YndJ-like protein
FMFMHKIL_03820 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
FMFMHKIL_03821 1.85e-198 yndG - - S - - - DoxX-like family
FMFMHKIL_03822 5.57e-289 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
FMFMHKIL_03823 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
FMFMHKIL_03824 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
FMFMHKIL_03827 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
FMFMHKIL_03828 8.92e-96 - - - - - - - -
FMFMHKIL_03829 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
FMFMHKIL_03832 4.44e-172 - - - S - - - Domain of unknown function, YrpD
FMFMHKIL_03834 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FMFMHKIL_03837 7.54e-22 - - - - - - - -
FMFMHKIL_03838 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
FMFMHKIL_03839 1.56e-97 - - - J - - - FR47-like protein
FMFMHKIL_03840 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_03841 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMFMHKIL_03842 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
FMFMHKIL_03843 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
FMFMHKIL_03844 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
FMFMHKIL_03845 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
FMFMHKIL_03846 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FMFMHKIL_03847 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FMFMHKIL_03848 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
FMFMHKIL_03849 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
FMFMHKIL_03850 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
FMFMHKIL_03851 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FMFMHKIL_03852 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
FMFMHKIL_03853 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
FMFMHKIL_03854 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FMFMHKIL_03855 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMFMHKIL_03856 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
FMFMHKIL_03857 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
FMFMHKIL_03858 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FMFMHKIL_03859 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
FMFMHKIL_03860 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FMFMHKIL_03861 7.42e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FMFMHKIL_03862 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FMFMHKIL_03863 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FMFMHKIL_03864 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
FMFMHKIL_03865 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMFMHKIL_03866 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMFMHKIL_03867 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
FMFMHKIL_03868 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FMFMHKIL_03869 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FMFMHKIL_03870 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FMFMHKIL_03871 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FMFMHKIL_03872 8.68e-229 ybaC - - S - - - Alpha/beta hydrolase family
FMFMHKIL_03873 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
FMFMHKIL_03874 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FMFMHKIL_03875 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
FMFMHKIL_03876 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FMFMHKIL_03877 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FMFMHKIL_03878 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FMFMHKIL_03879 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FMFMHKIL_03880 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FMFMHKIL_03881 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FMFMHKIL_03882 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
FMFMHKIL_03883 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FMFMHKIL_03884 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FMFMHKIL_03885 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FMFMHKIL_03886 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FMFMHKIL_03887 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FMFMHKIL_03888 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FMFMHKIL_03889 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FMFMHKIL_03890 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FMFMHKIL_03891 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FMFMHKIL_03892 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
FMFMHKIL_03893 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
FMFMHKIL_03894 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FMFMHKIL_03895 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FMFMHKIL_03896 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
FMFMHKIL_03897 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FMFMHKIL_03898 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
FMFMHKIL_03899 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FMFMHKIL_03900 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FMFMHKIL_03901 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMFMHKIL_03902 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
FMFMHKIL_03903 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMFMHKIL_03904 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMFMHKIL_03905 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMFMHKIL_03906 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FMFMHKIL_03907 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FMFMHKIL_03908 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
FMFMHKIL_03909 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
FMFMHKIL_03910 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
FMFMHKIL_03911 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
FMFMHKIL_03912 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
FMFMHKIL_03913 1.04e-122 gerD - - - ko:K06294 - ko00000 -
FMFMHKIL_03914 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
FMFMHKIL_03915 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
FMFMHKIL_03916 3.86e-183 yoaP - - K - - - YoaP-like
FMFMHKIL_03918 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
FMFMHKIL_03921 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
FMFMHKIL_03922 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
FMFMHKIL_03923 1.79e-145 yoaK - - S - - - Membrane
FMFMHKIL_03924 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
FMFMHKIL_03925 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
FMFMHKIL_03926 6.22e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
FMFMHKIL_03927 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
FMFMHKIL_03928 1.46e-19 - - - - - - - -
FMFMHKIL_03931 7.24e-45 yoaF - - - - - - -
FMFMHKIL_03932 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FMFMHKIL_03933 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMFMHKIL_03934 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
FMFMHKIL_03935 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
FMFMHKIL_03936 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
FMFMHKIL_03937 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
FMFMHKIL_03938 7.43e-119 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FMFMHKIL_03939 5.79e-171 yoxB - - - - - - -
FMFMHKIL_03940 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
FMFMHKIL_03941 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMFMHKIL_03942 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
FMFMHKIL_03943 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FMFMHKIL_03944 1.91e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FMFMHKIL_03945 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_03946 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
FMFMHKIL_03947 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
FMFMHKIL_03948 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
FMFMHKIL_03949 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_03950 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
FMFMHKIL_03951 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
FMFMHKIL_03952 1.14e-124 - - - L - - - Integrase
FMFMHKIL_03954 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
FMFMHKIL_03955 1.33e-310 yoeA - - V - - - MATE efflux family protein
FMFMHKIL_03956 9.53e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
FMFMHKIL_03957 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
FMFMHKIL_03960 3.17e-23 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
FMFMHKIL_03961 4.98e-106 yoaW - - - - - - -
FMFMHKIL_03962 7.83e-08 ywlA - - S - - - Uncharacterised protein family (UPF0715)
FMFMHKIL_03963 6.01e-96 - - - - - - - -
FMFMHKIL_03969 5.79e-258 - - - - - - - -
FMFMHKIL_03972 0.0 - - - - - - - -
FMFMHKIL_03973 1.17e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FMFMHKIL_03974 1.21e-257 - - - - - - - -
FMFMHKIL_03977 2.96e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
FMFMHKIL_03979 1.64e-85 - - - - - - - -
FMFMHKIL_03980 6.98e-225 - - - - - - - -
FMFMHKIL_03981 0.0 - - - - - - - -
FMFMHKIL_03982 0.0 - - - - - - - -
FMFMHKIL_03983 7.15e-122 - - - - - - - -
FMFMHKIL_03984 9.83e-236 - - - - - - - -
FMFMHKIL_03985 2.31e-105 - - - - - - - -
FMFMHKIL_03991 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
FMFMHKIL_03992 6.81e-66 - - - S - - - Tetratricopeptide repeat
FMFMHKIL_03995 2.37e-70 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
FMFMHKIL_03997 1.87e-113 - - - - - - - -
FMFMHKIL_03998 1.04e-217 yoaR - - V - - - vancomycin resistance protein
FMFMHKIL_03999 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
FMFMHKIL_04000 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_04001 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
FMFMHKIL_04002 1.11e-201 yoaU - - K - - - LysR substrate binding domain
FMFMHKIL_04003 3.7e-201 yoaV - - EG - - - EamA-like transporter family
FMFMHKIL_04004 1.89e-100 yoaW - - - - - - -
FMFMHKIL_04005 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
FMFMHKIL_04006 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
FMFMHKIL_04009 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
FMFMHKIL_04010 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
FMFMHKIL_04011 1e-47 - - - S - - - TM2 domain
FMFMHKIL_04012 7.63e-74 - - - K - - - Helix-turn-helix
FMFMHKIL_04015 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
FMFMHKIL_04019 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FMFMHKIL_04020 4.33e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
FMFMHKIL_04021 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FMFMHKIL_04022 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
FMFMHKIL_04023 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
FMFMHKIL_04024 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
FMFMHKIL_04025 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
FMFMHKIL_04026 6.8e-309 ymfH - - S - - - zinc protease
FMFMHKIL_04027 1.46e-178 albE - - S - - - Peptidase M16
FMFMHKIL_04028 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
FMFMHKIL_04029 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
FMFMHKIL_04030 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FMFMHKIL_04031 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FMFMHKIL_04032 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
FMFMHKIL_04033 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FMFMHKIL_04034 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
FMFMHKIL_04035 6.62e-99 ylxL - - - - - - -
FMFMHKIL_04036 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FMFMHKIL_04037 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
FMFMHKIL_04038 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
FMFMHKIL_04039 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
FMFMHKIL_04040 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
FMFMHKIL_04041 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
FMFMHKIL_04042 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
FMFMHKIL_04043 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
FMFMHKIL_04044 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FMFMHKIL_04045 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FMFMHKIL_04046 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
FMFMHKIL_04047 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
FMFMHKIL_04048 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
FMFMHKIL_04049 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
FMFMHKIL_04050 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
FMFMHKIL_04051 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FMFMHKIL_04052 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FMFMHKIL_04053 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
FMFMHKIL_04054 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
FMFMHKIL_04055 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
FMFMHKIL_04056 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
FMFMHKIL_04057 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
FMFMHKIL_04058 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
FMFMHKIL_04059 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
FMFMHKIL_04060 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
FMFMHKIL_04061 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FMFMHKIL_04062 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
FMFMHKIL_04063 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
FMFMHKIL_04064 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
FMFMHKIL_04065 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
FMFMHKIL_04066 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FMFMHKIL_04067 4.07e-107 yocK - - T - - - general stress protein
FMFMHKIL_04068 3.02e-70 yocL - - - - - - -
FMFMHKIL_04069 3.93e-41 - - - - - - - -
FMFMHKIL_04070 2.21e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
FMFMHKIL_04071 2.94e-55 yozN - - - - - - -
FMFMHKIL_04072 1.83e-49 yocN - - - - - - -
FMFMHKIL_04073 2.17e-74 yozO - - S - - - Bacterial PH domain
FMFMHKIL_04074 1.91e-42 yozC - - - - - - -
FMFMHKIL_04075 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FMFMHKIL_04076 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
FMFMHKIL_04077 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
FMFMHKIL_04078 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FMFMHKIL_04079 4.5e-212 yocS - - S ko:K03453 - ko00000 -transporter
FMFMHKIL_04080 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
FMFMHKIL_04081 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
FMFMHKIL_04082 0.0 yojO - - P - - - Von Willebrand factor
FMFMHKIL_04083 3.82e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
FMFMHKIL_04084 7.31e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FMFMHKIL_04085 7.5e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
FMFMHKIL_04086 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
FMFMHKIL_04087 1.19e-138 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FMFMHKIL_04089 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
FMFMHKIL_04090 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FMFMHKIL_04091 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
FMFMHKIL_04092 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
FMFMHKIL_04093 1.07e-57 - - - - - - - -
FMFMHKIL_04094 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
FMFMHKIL_04095 7.69e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
FMFMHKIL_04096 5.59e-14 - - - - - - - -
FMFMHKIL_04097 1.6e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
FMFMHKIL_04098 3.97e-84 iolK - - S - - - tautomerase
FMFMHKIL_04099 2.63e-73 yodB - - K - - - transcriptional
FMFMHKIL_04100 1.11e-139 yodC - - C - - - nitroreductase
FMFMHKIL_04101 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
FMFMHKIL_04102 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
FMFMHKIL_04103 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
FMFMHKIL_04104 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FMFMHKIL_04105 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
FMFMHKIL_04106 3.69e-167 yodH - - Q - - - Methyltransferase
FMFMHKIL_04107 8.39e-42 yodI - - - - - - -
FMFMHKIL_04108 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
FMFMHKIL_04109 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
FMFMHKIL_04110 2.08e-12 - - - - - - - -
FMFMHKIL_04111 1.17e-71 yodL - - S - - - YodL-like
FMFMHKIL_04112 2.14e-133 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
FMFMHKIL_04113 5.18e-34 yozD - - S - - - YozD-like protein
FMFMHKIL_04115 1.29e-159 yodN - - - - - - -
FMFMHKIL_04116 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
FMFMHKIL_04117 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
FMFMHKIL_04118 2.43e-65 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
FMFMHKIL_04119 4.3e-54 - - - S - - - Domain of unknown function (DUF4652)
FMFMHKIL_04122 1.11e-40 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
FMFMHKIL_04124 4.12e-118 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FMFMHKIL_04127 2.22e-40 - - - S - - - Macro domain
FMFMHKIL_04137 1.84e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
FMFMHKIL_04141 1.35e-44 - - - - - - - -
FMFMHKIL_04143 3.29e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FMFMHKIL_04144 3.08e-207 - - - S - - - Thymidylate synthase
FMFMHKIL_04148 1.71e-17 XK27_09885 - - V - - - COG4767 Glycopeptide antibiotics resistance protein
FMFMHKIL_04149 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
FMFMHKIL_04150 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FMFMHKIL_04151 1.81e-41 yazB - - K - - - transcriptional
FMFMHKIL_04152 9.21e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FMFMHKIL_04153 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FMFMHKIL_04154 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FMFMHKIL_04155 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
FMFMHKIL_04156 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
FMFMHKIL_04157 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FMFMHKIL_04158 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FMFMHKIL_04159 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
FMFMHKIL_04160 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FMFMHKIL_04161 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FMFMHKIL_04162 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FMFMHKIL_04163 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
FMFMHKIL_04164 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FMFMHKIL_04165 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
FMFMHKIL_04166 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
FMFMHKIL_04167 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
FMFMHKIL_04170 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
FMFMHKIL_04171 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
FMFMHKIL_04172 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
FMFMHKIL_04173 1.91e-66 yabP - - S - - - Sporulation protein YabP
FMFMHKIL_04174 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
FMFMHKIL_04175 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
FMFMHKIL_04176 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FMFMHKIL_04177 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
FMFMHKIL_04178 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FMFMHKIL_04179 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
FMFMHKIL_04180 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FMFMHKIL_04181 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FMFMHKIL_04182 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FMFMHKIL_04183 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FMFMHKIL_04184 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
FMFMHKIL_04185 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
FMFMHKIL_04186 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
FMFMHKIL_04187 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FMFMHKIL_04188 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
FMFMHKIL_04189 5.32e-53 veg - - S - - - protein conserved in bacteria
FMFMHKIL_04190 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
FMFMHKIL_04191 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FMFMHKIL_04192 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FMFMHKIL_04193 1.18e-277 yabE - - T - - - protein conserved in bacteria
FMFMHKIL_04194 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
FMFMHKIL_04195 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FMFMHKIL_04196 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
FMFMHKIL_04197 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FMFMHKIL_04198 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
FMFMHKIL_04199 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
FMFMHKIL_04200 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
FMFMHKIL_04201 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
FMFMHKIL_04202 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
FMFMHKIL_04203 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
FMFMHKIL_04204 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
FMFMHKIL_04205 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FMFMHKIL_04206 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
FMFMHKIL_04207 8.37e-259 yaaN - - P - - - Belongs to the TelA family
FMFMHKIL_04208 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
FMFMHKIL_04209 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
FMFMHKIL_04210 6.37e-123 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
FMFMHKIL_04211 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FMFMHKIL_04212 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMFMHKIL_04213 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
FMFMHKIL_04214 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
FMFMHKIL_04215 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
FMFMHKIL_04216 6.16e-63 ylxQ - - J - - - ribosomal protein
FMFMHKIL_04217 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FMFMHKIL_04218 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
FMFMHKIL_04219 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FMFMHKIL_04220 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FMFMHKIL_04221 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
FMFMHKIL_04222 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FMFMHKIL_04223 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FMFMHKIL_04224 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
FMFMHKIL_04225 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
FMFMHKIL_04226 1.53e-56 ymxH - - S - - - YlmC YmxH family
FMFMHKIL_04227 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
FMFMHKIL_04228 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
FMFMHKIL_04229 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FMFMHKIL_04230 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
FMFMHKIL_04231 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMFMHKIL_04232 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FMFMHKIL_04233 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
FMFMHKIL_04234 4.94e-44 - - - S - - - YlzJ-like protein
FMFMHKIL_04235 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
FMFMHKIL_04236 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_04237 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
FMFMHKIL_04242 8.82e-22 - - - - - - - -
FMFMHKIL_04248 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
FMFMHKIL_04249 6.81e-225 - - - - - - - -
FMFMHKIL_04250 0.0 - - - S - - - DNA-sulfur modification-associated
FMFMHKIL_04251 2.9e-254 - - - L - - - Belongs to the 'phage' integrase family
FMFMHKIL_04256 1.6e-134 - - - - - - - -
FMFMHKIL_04259 4.16e-08 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
FMFMHKIL_04265 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
FMFMHKIL_04266 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
FMFMHKIL_04267 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FMFMHKIL_04268 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FMFMHKIL_04269 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMFMHKIL_04270 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FMFMHKIL_04271 1.89e-123 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
FMFMHKIL_04272 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
FMFMHKIL_04273 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
FMFMHKIL_04274 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
FMFMHKIL_04276 6.6e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FMFMHKIL_04277 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FMFMHKIL_04278 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FMFMHKIL_04279 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FMFMHKIL_04280 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
FMFMHKIL_04281 2.14e-232 yaaC - - S - - - YaaC-like Protein
FMFMHKIL_04297 3.36e-68 yobS - - K - - - Transcriptional regulator
FMFMHKIL_04298 5.51e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
FMFMHKIL_04300 5.4e-09 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
FMFMHKIL_04301 6.52e-176 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
FMFMHKIL_04302 3.05e-69 yocH - - M - - - COG1388 FOG LysM repeat
FMFMHKIL_04303 8.53e-61 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FMFMHKIL_04304 3e-55 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FMFMHKIL_04305 5.21e-26 - - - - - - - -
FMFMHKIL_04306 4.79e-27 yokH - - G - - - SMI1 / KNR4 family
FMFMHKIL_04307 2.57e-101 yocC - - - - - - -
FMFMHKIL_04308 8.34e-155 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)