ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CLFLPBHK_00002 1.76e-10 - - - - - - - -
CLFLPBHK_00003 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
CLFLPBHK_00004 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
CLFLPBHK_00007 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
CLFLPBHK_00008 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_00011 5.28e-79 - - - - - - - -
CLFLPBHK_00012 4.26e-43 - - - S - - - Phage integrase family
CLFLPBHK_00013 2.09e-81 - - - S - - - Phage integrase family
CLFLPBHK_00015 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CLFLPBHK_00016 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CLFLPBHK_00017 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
CLFLPBHK_00018 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
CLFLPBHK_00019 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
CLFLPBHK_00020 4.9e-48 yvzC - - K - - - transcriptional
CLFLPBHK_00021 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
CLFLPBHK_00022 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CLFLPBHK_00023 3.85e-72 yvaP - - K - - - transcriptional
CLFLPBHK_00024 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_00025 3.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CLFLPBHK_00026 7.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CLFLPBHK_00027 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CLFLPBHK_00028 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CLFLPBHK_00029 3.28e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CLFLPBHK_00030 1.13e-135 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CLFLPBHK_00031 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CLFLPBHK_00032 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CLFLPBHK_00033 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CLFLPBHK_00034 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CLFLPBHK_00035 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
CLFLPBHK_00036 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
CLFLPBHK_00037 2.66e-155 yvbI - - M - - - Membrane
CLFLPBHK_00038 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
CLFLPBHK_00039 9.77e-106 yvbK - - K - - - acetyltransferase
CLFLPBHK_00040 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CLFLPBHK_00041 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
CLFLPBHK_00042 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CLFLPBHK_00043 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CLFLPBHK_00044 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CLFLPBHK_00045 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CLFLPBHK_00046 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_00047 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
CLFLPBHK_00048 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLFLPBHK_00049 1.99e-205 yvbU - - K - - - Transcriptional regulator
CLFLPBHK_00050 5.59e-198 yvbV - - EG - - - EamA-like transporter family
CLFLPBHK_00051 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_00052 2.7e-187 - - - S - - - Glycosyl hydrolase
CLFLPBHK_00053 6.88e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CLFLPBHK_00054 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CLFLPBHK_00055 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CLFLPBHK_00056 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
CLFLPBHK_00057 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
CLFLPBHK_00058 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_00059 1.09e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_00060 8.31e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
CLFLPBHK_00061 1.1e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
CLFLPBHK_00062 8.47e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
CLFLPBHK_00063 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
CLFLPBHK_00064 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
CLFLPBHK_00065 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
CLFLPBHK_00066 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
CLFLPBHK_00067 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
CLFLPBHK_00068 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
CLFLPBHK_00069 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_00070 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
CLFLPBHK_00071 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CLFLPBHK_00072 7.05e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CLFLPBHK_00073 5.69e-44 yvfG - - S - - - YvfG protein
CLFLPBHK_00074 3.07e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
CLFLPBHK_00075 1.06e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
CLFLPBHK_00076 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CLFLPBHK_00077 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CLFLPBHK_00078 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_00079 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CLFLPBHK_00080 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
CLFLPBHK_00081 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CLFLPBHK_00082 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
CLFLPBHK_00083 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CLFLPBHK_00084 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
CLFLPBHK_00085 5.25e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
CLFLPBHK_00086 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CLFLPBHK_00087 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CLFLPBHK_00088 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
CLFLPBHK_00089 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
CLFLPBHK_00090 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
CLFLPBHK_00092 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
CLFLPBHK_00093 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
CLFLPBHK_00094 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
CLFLPBHK_00095 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CLFLPBHK_00096 1.78e-223 pbpE - - V - - - Beta-lactamase
CLFLPBHK_00097 3.77e-79 pbpE - - V - - - Beta-lactamase
CLFLPBHK_00098 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
CLFLPBHK_00099 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
CLFLPBHK_00100 0.0 ybeC - - E - - - amino acid
CLFLPBHK_00101 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
CLFLPBHK_00102 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CLFLPBHK_00103 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
CLFLPBHK_00104 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
CLFLPBHK_00106 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CLFLPBHK_00107 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CLFLPBHK_00108 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CLFLPBHK_00109 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
CLFLPBHK_00110 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
CLFLPBHK_00111 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
CLFLPBHK_00112 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
CLFLPBHK_00113 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
CLFLPBHK_00114 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
CLFLPBHK_00115 1.54e-221 yvdE - - K - - - Transcriptional regulator
CLFLPBHK_00116 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
CLFLPBHK_00117 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
CLFLPBHK_00118 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CLFLPBHK_00119 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CLFLPBHK_00120 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLFLPBHK_00121 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
CLFLPBHK_00122 3.67e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00123 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
CLFLPBHK_00124 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_00125 7.42e-29 - - - - - - - -
CLFLPBHK_00126 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
CLFLPBHK_00127 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
CLFLPBHK_00128 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CLFLPBHK_00129 5.52e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CLFLPBHK_00130 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CLFLPBHK_00131 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CLFLPBHK_00132 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CLFLPBHK_00133 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
CLFLPBHK_00134 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
CLFLPBHK_00135 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
CLFLPBHK_00137 0.0 - - - - - - - -
CLFLPBHK_00138 3.7e-111 - - - - - - - -
CLFLPBHK_00139 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
CLFLPBHK_00140 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CLFLPBHK_00141 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CLFLPBHK_00142 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CLFLPBHK_00143 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
CLFLPBHK_00144 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CLFLPBHK_00145 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CLFLPBHK_00146 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CLFLPBHK_00147 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
CLFLPBHK_00148 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
CLFLPBHK_00149 0.0 ytcJ - - S - - - amidohydrolase
CLFLPBHK_00150 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CLFLPBHK_00151 5.88e-38 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
CLFLPBHK_00152 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CLFLPBHK_00153 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CLFLPBHK_00154 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CLFLPBHK_00155 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CLFLPBHK_00156 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CLFLPBHK_00157 9.83e-141 yttP - - K - - - Transcriptional regulator
CLFLPBHK_00158 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
CLFLPBHK_00159 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
CLFLPBHK_00160 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CLFLPBHK_00162 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLFLPBHK_00163 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CLFLPBHK_00164 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CLFLPBHK_00165 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
CLFLPBHK_00166 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
CLFLPBHK_00167 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CLFLPBHK_00168 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CLFLPBHK_00169 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CLFLPBHK_00170 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CLFLPBHK_00171 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
CLFLPBHK_00172 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
CLFLPBHK_00173 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CLFLPBHK_00174 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CLFLPBHK_00175 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CLFLPBHK_00176 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLFLPBHK_00177 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
CLFLPBHK_00178 3.17e-75 ytpP - - CO - - - Thioredoxin
CLFLPBHK_00179 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
CLFLPBHK_00180 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
CLFLPBHK_00181 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
CLFLPBHK_00182 1.17e-67 ytzB - - S - - - small secreted protein
CLFLPBHK_00183 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CLFLPBHK_00184 3.05e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CLFLPBHK_00185 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CLFLPBHK_00186 9.51e-61 ytzH - - S - - - YtzH-like protein
CLFLPBHK_00187 3.02e-192 ytmP - - M - - - Phosphotransferase
CLFLPBHK_00188 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
CLFLPBHK_00189 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CLFLPBHK_00190 9.92e-212 ytlQ - - - - - - -
CLFLPBHK_00191 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CLFLPBHK_00192 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CLFLPBHK_00193 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
CLFLPBHK_00194 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
CLFLPBHK_00195 1.12e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
CLFLPBHK_00196 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CLFLPBHK_00197 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
CLFLPBHK_00198 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CLFLPBHK_00199 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_00200 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
CLFLPBHK_00201 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
CLFLPBHK_00202 2.14e-36 yteV - - S - - - Sporulation protein Cse60
CLFLPBHK_00204 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
CLFLPBHK_00205 9.64e-94 yteS - - G - - - transport
CLFLPBHK_00206 8.3e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CLFLPBHK_00207 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
CLFLPBHK_00208 1.36e-202 ytdP - - K - - - Transcriptional regulator
CLFLPBHK_00209 2.13e-75 ytdP - - K - - - Transcriptional regulator
CLFLPBHK_00210 1.13e-165 ytdP - - K - - - Transcriptional regulator
CLFLPBHK_00211 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
CLFLPBHK_00212 1.19e-190 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CLFLPBHK_00213 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
CLFLPBHK_00214 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CLFLPBHK_00215 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CLFLPBHK_00216 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CLFLPBHK_00217 4.1e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CLFLPBHK_00218 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CLFLPBHK_00219 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CLFLPBHK_00220 4.8e-221 - - - S - - - Acetyl xylan esterase (AXE1)
CLFLPBHK_00221 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_00222 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CLFLPBHK_00223 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_00224 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CLFLPBHK_00225 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
CLFLPBHK_00226 1.22e-68 ytwF - - P - - - Sulfurtransferase
CLFLPBHK_00227 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CLFLPBHK_00228 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
CLFLPBHK_00229 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CLFLPBHK_00230 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
CLFLPBHK_00231 5.71e-41 yttA - - S - - - Pfam Transposase IS66
CLFLPBHK_00232 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
CLFLPBHK_00233 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00234 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
CLFLPBHK_00235 2.23e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_00236 3.99e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CLFLPBHK_00237 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00238 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
CLFLPBHK_00239 4.46e-211 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_00240 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00241 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
CLFLPBHK_00243 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
CLFLPBHK_00244 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
CLFLPBHK_00245 2.75e-136 ytqB - - J - - - Putative rRNA methylase
CLFLPBHK_00246 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
CLFLPBHK_00247 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
CLFLPBHK_00248 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CLFLPBHK_00249 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_00250 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CLFLPBHK_00251 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CLFLPBHK_00252 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CLFLPBHK_00253 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
CLFLPBHK_00254 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CLFLPBHK_00255 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CLFLPBHK_00256 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CLFLPBHK_00257 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CLFLPBHK_00258 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CLFLPBHK_00259 1.52e-79 ytkC - - S - - - Bacteriophage holin family
CLFLPBHK_00260 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CLFLPBHK_00262 4.78e-95 ytkA - - S - - - YtkA-like
CLFLPBHK_00263 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CLFLPBHK_00264 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CLFLPBHK_00265 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CLFLPBHK_00266 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CLFLPBHK_00267 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CLFLPBHK_00268 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
CLFLPBHK_00269 7.92e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CLFLPBHK_00270 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CLFLPBHK_00271 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CLFLPBHK_00272 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CLFLPBHK_00273 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CLFLPBHK_00274 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CLFLPBHK_00275 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CLFLPBHK_00276 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CLFLPBHK_00277 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CLFLPBHK_00278 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CLFLPBHK_00279 1.44e-167 yteA - - T - - - COG1734 DnaK suppressor protein
CLFLPBHK_00280 5.69e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
CLFLPBHK_00281 4.1e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLFLPBHK_00282 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
CLFLPBHK_00283 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
CLFLPBHK_00285 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
CLFLPBHK_00286 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
CLFLPBHK_00287 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
CLFLPBHK_00288 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
CLFLPBHK_00289 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CLFLPBHK_00290 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
CLFLPBHK_00291 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
CLFLPBHK_00292 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CLFLPBHK_00293 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CLFLPBHK_00315 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
CLFLPBHK_00316 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
CLFLPBHK_00317 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
CLFLPBHK_00321 2.98e-53 - - - - - - - -
CLFLPBHK_00322 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
CLFLPBHK_00323 5.9e-171 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CLFLPBHK_00324 9.99e-59 - - - - - - - -
CLFLPBHK_00325 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
CLFLPBHK_00326 9.13e-135 ywqM - - K - - - Transcriptional regulator
CLFLPBHK_00327 8.96e-153 - - - E - - - amino acid
CLFLPBHK_00335 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CLFLPBHK_00336 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
CLFLPBHK_00337 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
CLFLPBHK_00338 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_00339 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CLFLPBHK_00340 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
CLFLPBHK_00341 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
CLFLPBHK_00342 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CLFLPBHK_00343 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
CLFLPBHK_00344 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
CLFLPBHK_00345 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
CLFLPBHK_00346 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CLFLPBHK_00347 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLFLPBHK_00348 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
CLFLPBHK_00349 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CLFLPBHK_00350 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
CLFLPBHK_00351 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
CLFLPBHK_00352 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
CLFLPBHK_00353 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CLFLPBHK_00354 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CLFLPBHK_00355 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CLFLPBHK_00356 4.19e-75 ydbP - - CO - - - Thioredoxin
CLFLPBHK_00357 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLFLPBHK_00359 1.49e-26 - - - S - - - Fur-regulated basic protein B
CLFLPBHK_00360 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
CLFLPBHK_00361 3.8e-69 ydbL - - - - - - -
CLFLPBHK_00362 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CLFLPBHK_00363 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00364 1.32e-230 ydbI - - S - - - AI-2E family transporter
CLFLPBHK_00365 7.33e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLFLPBHK_00366 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CLFLPBHK_00367 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CLFLPBHK_00368 4.99e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CLFLPBHK_00369 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
CLFLPBHK_00370 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
CLFLPBHK_00371 2.17e-78 ydbB - - G - - - Cupin domain
CLFLPBHK_00372 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
CLFLPBHK_00373 4.3e-190 ydbA - - P - - - EcsC protein family
CLFLPBHK_00374 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
CLFLPBHK_00375 1.67e-42 ydaS - - S - - - membrane
CLFLPBHK_00376 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CLFLPBHK_00377 6.14e-53 - - - - - - - -
CLFLPBHK_00379 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
CLFLPBHK_00380 1.84e-34 - - - - - - - -
CLFLPBHK_00381 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CLFLPBHK_00382 5.12e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CLFLPBHK_00383 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLFLPBHK_00384 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CLFLPBHK_00385 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
CLFLPBHK_00386 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CLFLPBHK_00387 6.13e-100 ydaG - - S - - - general stress protein
CLFLPBHK_00388 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CLFLPBHK_00389 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
CLFLPBHK_00390 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_00391 1e-127 ydaC - - Q - - - Methyltransferase domain
CLFLPBHK_00392 0.0 ydaB - - IQ - - - acyl-CoA ligase
CLFLPBHK_00393 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
CLFLPBHK_00394 8.6e-220 ycsN - - S - - - Oxidoreductase
CLFLPBHK_00395 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
CLFLPBHK_00396 8.97e-65 yczJ - - S - - - biosynthesis
CLFLPBHK_00398 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
CLFLPBHK_00399 1.55e-170 kipR - - K - - - Transcriptional regulator
CLFLPBHK_00400 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
CLFLPBHK_00401 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
CLFLPBHK_00402 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
CLFLPBHK_00403 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
CLFLPBHK_00404 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
CLFLPBHK_00405 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CLFLPBHK_00406 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CLFLPBHK_00407 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CLFLPBHK_00408 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
CLFLPBHK_00409 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CLFLPBHK_00410 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CLFLPBHK_00411 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
CLFLPBHK_00412 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CLFLPBHK_00413 8.92e-44 ylaI - - S - - - protein conserved in bacteria
CLFLPBHK_00414 4.4e-63 ylaH - - S - - - YlaH-like protein
CLFLPBHK_00415 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CLFLPBHK_00416 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
CLFLPBHK_00417 1.74e-57 ylaE - - - - - - -
CLFLPBHK_00419 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_00420 1.44e-56 ylaB - - - - - - -
CLFLPBHK_00421 0.0 ylaA - - - - - - -
CLFLPBHK_00422 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
CLFLPBHK_00423 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CLFLPBHK_00424 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
CLFLPBHK_00425 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
CLFLPBHK_00426 4.48e-35 ykzI - - - - - - -
CLFLPBHK_00427 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
CLFLPBHK_00428 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
CLFLPBHK_00429 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
CLFLPBHK_00430 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CLFLPBHK_00431 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CLFLPBHK_00432 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CLFLPBHK_00433 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
CLFLPBHK_00434 2.02e-138 ypfA - - M - - - Flagellar protein YcgR
CLFLPBHK_00435 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
CLFLPBHK_00436 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
CLFLPBHK_00437 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
CLFLPBHK_00438 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
CLFLPBHK_00439 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CLFLPBHK_00440 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CLFLPBHK_00441 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
CLFLPBHK_00442 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
CLFLPBHK_00443 5.04e-148 ypbE - - M - - - Lysin motif
CLFLPBHK_00444 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
CLFLPBHK_00445 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CLFLPBHK_00446 3.14e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
CLFLPBHK_00447 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
CLFLPBHK_00448 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CLFLPBHK_00449 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CLFLPBHK_00450 9.27e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CLFLPBHK_00451 2.96e-135 rsiX - - - - - - -
CLFLPBHK_00452 8.11e-17 rsiX - - - - - - -
CLFLPBHK_00453 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_00454 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_00455 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_00456 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CLFLPBHK_00457 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
CLFLPBHK_00458 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CLFLPBHK_00459 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CLFLPBHK_00460 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
CLFLPBHK_00461 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
CLFLPBHK_00462 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CLFLPBHK_00463 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_00465 1.09e-34 - - - S - - - YCII-related domain
CLFLPBHK_00466 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CLFLPBHK_00467 1.35e-80 yjqA - - S - - - Bacterial PH domain
CLFLPBHK_00468 1.11e-138 yjqB - - S - - - Pfam:DUF867
CLFLPBHK_00469 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
CLFLPBHK_00470 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
CLFLPBHK_00471 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_00473 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
CLFLPBHK_00474 8.72e-152 xkdC - - L - - - Bacterial dnaA protein
CLFLPBHK_00479 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CLFLPBHK_00480 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
CLFLPBHK_00481 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
CLFLPBHK_00482 0.0 yqbA - - S - - - portal protein
CLFLPBHK_00483 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
CLFLPBHK_00484 3.91e-217 xkdG - - S - - - Phage capsid family
CLFLPBHK_00485 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
CLFLPBHK_00486 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
CLFLPBHK_00487 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLFLPBHK_00488 2.87e-101 xkdJ - - - - - - -
CLFLPBHK_00489 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
CLFLPBHK_00490 2.45e-98 xkdM - - S - - - Phage tail tube protein
CLFLPBHK_00491 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
CLFLPBHK_00492 0.0 xkdO - - L - - - Transglycosylase SLT domain
CLFLPBHK_00493 1.73e-151 xkdP - - S - - - Lysin motif
CLFLPBHK_00494 2.31e-232 xkdQ - - G - - - NLP P60 protein
CLFLPBHK_00495 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
CLFLPBHK_00496 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
CLFLPBHK_00497 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CLFLPBHK_00498 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
CLFLPBHK_00499 4.43e-56 - - - - - - - -
CLFLPBHK_00500 0.0 - - - - - - - -
CLFLPBHK_00501 2.7e-68 xkdW - - S - - - XkdW protein
CLFLPBHK_00502 6.35e-31 xkdX - - - - - - -
CLFLPBHK_00503 9.79e-195 xepA - - - - - - -
CLFLPBHK_00504 2.21e-51 xhlA - - S - - - Haemolysin XhlA
CLFLPBHK_00505 1.15e-52 xhlB - - S - - - SPP1 phage holin
CLFLPBHK_00506 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_00507 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
CLFLPBHK_00508 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
CLFLPBHK_00509 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
CLFLPBHK_00510 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
CLFLPBHK_00511 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
CLFLPBHK_00512 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CLFLPBHK_00513 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLFLPBHK_00514 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CLFLPBHK_00516 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLFLPBHK_00517 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
CLFLPBHK_00518 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
CLFLPBHK_00519 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_00520 8.28e-222 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_00521 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_00522 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CLFLPBHK_00524 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
CLFLPBHK_00525 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CLFLPBHK_00526 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CLFLPBHK_00527 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_00528 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
CLFLPBHK_00529 9.79e-102 ykgA - - E - - - Amidinotransferase
CLFLPBHK_00530 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
CLFLPBHK_00531 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CLFLPBHK_00532 9.93e-15 - - - - - - - -
CLFLPBHK_00533 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_00534 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
CLFLPBHK_00535 6.97e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CLFLPBHK_00536 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
CLFLPBHK_00537 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
CLFLPBHK_00538 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CLFLPBHK_00539 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLFLPBHK_00540 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CLFLPBHK_00541 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
CLFLPBHK_00542 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
CLFLPBHK_00543 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
CLFLPBHK_00544 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
CLFLPBHK_00545 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CLFLPBHK_00546 6.07e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CLFLPBHK_00547 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CLFLPBHK_00548 5.18e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CLFLPBHK_00549 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00550 3.99e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
CLFLPBHK_00551 4.05e-141 ykoF - - S - - - YKOF-related Family
CLFLPBHK_00552 1.68e-156 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_00553 6.05e-307 ykoH - - T - - - Histidine kinase
CLFLPBHK_00554 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
CLFLPBHK_00555 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
CLFLPBHK_00556 1.45e-08 - - - - - - - -
CLFLPBHK_00558 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
CLFLPBHK_00559 1.49e-70 tnrA - - K - - - transcriptional
CLFLPBHK_00560 1.63e-25 - - - - - - - -
CLFLPBHK_00561 3.04e-36 ykoL - - - - - - -
CLFLPBHK_00562 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
CLFLPBHK_00563 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CLFLPBHK_00564 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
CLFLPBHK_00565 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
CLFLPBHK_00566 0.0 ykoS - - - - - - -
CLFLPBHK_00567 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
CLFLPBHK_00568 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
CLFLPBHK_00569 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CLFLPBHK_00570 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
CLFLPBHK_00571 1.71e-143 ykoX - - S - - - membrane-associated protein
CLFLPBHK_00572 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CLFLPBHK_00573 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_00574 3.83e-204 rsgI - - S - - - Anti-sigma factor N-terminus
CLFLPBHK_00575 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
CLFLPBHK_00576 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
CLFLPBHK_00577 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CLFLPBHK_00578 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
CLFLPBHK_00580 4.83e-30 ykzE - - - - - - -
CLFLPBHK_00581 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
CLFLPBHK_00582 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_00583 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CLFLPBHK_00585 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CLFLPBHK_00586 7.07e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CLFLPBHK_00587 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CLFLPBHK_00588 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLFLPBHK_00589 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CLFLPBHK_00590 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CLFLPBHK_00591 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CLFLPBHK_00592 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CLFLPBHK_00593 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
CLFLPBHK_00595 5.87e-74 eag - - - - - - -
CLFLPBHK_00596 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CLFLPBHK_00597 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
CLFLPBHK_00598 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CLFLPBHK_00599 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CLFLPBHK_00600 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
CLFLPBHK_00601 8.23e-228 ykvI - - S - - - membrane
CLFLPBHK_00602 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CLFLPBHK_00603 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
CLFLPBHK_00604 2.41e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CLFLPBHK_00605 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CLFLPBHK_00606 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
CLFLPBHK_00607 5.43e-35 ykvS - - S - - - protein conserved in bacteria
CLFLPBHK_00608 2.6e-39 - - - - - - - -
CLFLPBHK_00609 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
CLFLPBHK_00610 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_00611 1.12e-114 stoA - - CO - - - thiol-disulfide
CLFLPBHK_00612 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CLFLPBHK_00613 3.99e-09 - - - - - - - -
CLFLPBHK_00614 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CLFLPBHK_00615 2.21e-228 ykvZ - - K - - - Transcriptional regulator
CLFLPBHK_00616 1.97e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
CLFLPBHK_00617 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_00618 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
CLFLPBHK_00619 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CLFLPBHK_00620 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_00621 5.86e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
CLFLPBHK_00622 6.21e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_00623 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_00624 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CLFLPBHK_00626 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
CLFLPBHK_00627 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
CLFLPBHK_00628 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CLFLPBHK_00629 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
CLFLPBHK_00630 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CLFLPBHK_00631 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CLFLPBHK_00632 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
CLFLPBHK_00633 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CLFLPBHK_00634 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CLFLPBHK_00635 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
CLFLPBHK_00636 1.33e-160 ynaC - - - - - - -
CLFLPBHK_00637 8.25e-61 - - - S - - - Restriction endonuclease
CLFLPBHK_00638 7.12e-37 - - - - - - - -
CLFLPBHK_00639 1.14e-20 - - - S - - - peptidoglycan catabolic process
CLFLPBHK_00640 2.45e-34 - - - K - - - Helix-turn-helix domain
CLFLPBHK_00641 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLFLPBHK_00642 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CLFLPBHK_00643 1.81e-39 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CLFLPBHK_00644 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
CLFLPBHK_00645 3.26e-72 - - - L - - - transposase activity
CLFLPBHK_00646 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CLFLPBHK_00647 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CLFLPBHK_00648 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
CLFLPBHK_00649 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CLFLPBHK_00650 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
CLFLPBHK_00652 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CLFLPBHK_00653 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CLFLPBHK_00654 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
CLFLPBHK_00655 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CLFLPBHK_00656 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CLFLPBHK_00657 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLFLPBHK_00658 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CLFLPBHK_00659 1.05e-250 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CLFLPBHK_00660 6.06e-61 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CLFLPBHK_00661 7.75e-258 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
CLFLPBHK_00662 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_00663 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
CLFLPBHK_00664 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CLFLPBHK_00665 3.19e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CLFLPBHK_00667 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
CLFLPBHK_00668 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
CLFLPBHK_00669 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
CLFLPBHK_00670 5.4e-152 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
CLFLPBHK_00671 5.23e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
CLFLPBHK_00672 2.09e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_00673 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CLFLPBHK_00674 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CLFLPBHK_00676 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CLFLPBHK_00677 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CLFLPBHK_00679 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_00680 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_00681 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_00682 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
CLFLPBHK_00683 0.0 ycnB - - EGP - - - the major facilitator superfamily
CLFLPBHK_00684 5.87e-198 ycnC - - K - - - Transcriptional regulator
CLFLPBHK_00685 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CLFLPBHK_00686 1.68e-60 ycnE - - S - - - Monooxygenase
CLFLPBHK_00687 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CLFLPBHK_00688 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_00689 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLFLPBHK_00690 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CLFLPBHK_00691 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
CLFLPBHK_00692 3.27e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_00693 1.34e-132 ycnI - - S - - - protein conserved in bacteria
CLFLPBHK_00694 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
CLFLPBHK_00695 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CLFLPBHK_00696 1.34e-74 - - - - - - - -
CLFLPBHK_00697 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
CLFLPBHK_00698 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CLFLPBHK_00699 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
CLFLPBHK_00700 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
CLFLPBHK_00702 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CLFLPBHK_00703 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
CLFLPBHK_00704 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
CLFLPBHK_00706 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
CLFLPBHK_00707 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
CLFLPBHK_00709 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CLFLPBHK_00710 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CLFLPBHK_00711 8.73e-233 yqxL - - P - - - Mg2 transporter protein
CLFLPBHK_00712 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
CLFLPBHK_00713 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CLFLPBHK_00714 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
CLFLPBHK_00715 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
CLFLPBHK_00716 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
CLFLPBHK_00717 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
CLFLPBHK_00718 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
CLFLPBHK_00719 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
CLFLPBHK_00720 2.84e-36 yqzE - - S - - - YqzE-like protein
CLFLPBHK_00721 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
CLFLPBHK_00722 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
CLFLPBHK_00723 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
CLFLPBHK_00724 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
CLFLPBHK_00725 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
CLFLPBHK_00726 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
CLFLPBHK_00727 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
CLFLPBHK_00728 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CLFLPBHK_00729 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
CLFLPBHK_00730 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLFLPBHK_00731 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CLFLPBHK_00732 2.51e-81 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
CLFLPBHK_00733 2.63e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CLFLPBHK_00734 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CLFLPBHK_00735 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CLFLPBHK_00736 5.18e-81 yqhP - - - - - - -
CLFLPBHK_00737 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
CLFLPBHK_00738 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
CLFLPBHK_00739 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
CLFLPBHK_00740 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CLFLPBHK_00741 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CLFLPBHK_00742 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
CLFLPBHK_00743 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
CLFLPBHK_00744 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
CLFLPBHK_00745 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
CLFLPBHK_00746 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
CLFLPBHK_00747 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
CLFLPBHK_00748 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
CLFLPBHK_00749 7.6e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
CLFLPBHK_00750 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
CLFLPBHK_00751 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CLFLPBHK_00752 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CLFLPBHK_00753 9.55e-88 yqhY - - S - - - protein conserved in bacteria
CLFLPBHK_00754 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CLFLPBHK_00755 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CLFLPBHK_00756 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLFLPBHK_00757 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CLFLPBHK_00758 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CLFLPBHK_00759 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CLFLPBHK_00760 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
CLFLPBHK_00761 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CLFLPBHK_00762 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CLFLPBHK_00763 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
CLFLPBHK_00764 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CLFLPBHK_00766 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CLFLPBHK_00767 4.74e-37 - - - - - - - -
CLFLPBHK_00768 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
CLFLPBHK_00769 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CLFLPBHK_00770 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CLFLPBHK_00771 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
CLFLPBHK_00772 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
CLFLPBHK_00773 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CLFLPBHK_00774 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
CLFLPBHK_00775 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CLFLPBHK_00776 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
CLFLPBHK_00777 0.0 bkdR - - KT - - - Transcriptional regulator
CLFLPBHK_00778 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
CLFLPBHK_00779 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CLFLPBHK_00780 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
CLFLPBHK_00781 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CLFLPBHK_00782 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CLFLPBHK_00783 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CLFLPBHK_00784 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLFLPBHK_00785 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
CLFLPBHK_00786 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_00787 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CLFLPBHK_00788 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
CLFLPBHK_00789 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CLFLPBHK_00790 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CLFLPBHK_00791 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CLFLPBHK_00792 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
CLFLPBHK_00793 9.84e-128 yqjB - - S - - - protein conserved in bacteria
CLFLPBHK_00795 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
CLFLPBHK_00796 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CLFLPBHK_00797 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
CLFLPBHK_00798 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
CLFLPBHK_00799 1.47e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLFLPBHK_00800 4.35e-32 yqzJ - - - - - - -
CLFLPBHK_00801 1.06e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLFLPBHK_00802 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLFLPBHK_00803 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CLFLPBHK_00804 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CLFLPBHK_00805 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CLFLPBHK_00806 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CLFLPBHK_00807 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CLFLPBHK_00808 0.0 rocB - - E - - - arginine degradation protein
CLFLPBHK_00809 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
CLFLPBHK_00810 8.69e-184 - - - - - - - -
CLFLPBHK_00811 7.04e-118 yocC - - - - - - -
CLFLPBHK_00812 1.41e-242 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
CLFLPBHK_00813 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
CLFLPBHK_00814 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_00815 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_00817 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
CLFLPBHK_00818 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CLFLPBHK_00819 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLFLPBHK_00820 2.87e-107 yocK - - T - - - general stress protein
CLFLPBHK_00821 4.29e-70 yocL - - - - - - -
CLFLPBHK_00822 3.93e-41 - - - - - - - -
CLFLPBHK_00823 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CLFLPBHK_00824 2.94e-55 yozN - - - - - - -
CLFLPBHK_00825 1.83e-49 yocN - - - - - - -
CLFLPBHK_00826 2.17e-74 yozO - - S - - - Bacterial PH domain
CLFLPBHK_00827 1.91e-42 yozC - - - - - - -
CLFLPBHK_00828 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CLFLPBHK_00829 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
CLFLPBHK_00830 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
CLFLPBHK_00831 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CLFLPBHK_00832 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
CLFLPBHK_00833 1.05e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CLFLPBHK_00834 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CLFLPBHK_00835 0.0 yojO - - P - - - Von Willebrand factor
CLFLPBHK_00836 7.38e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
CLFLPBHK_00837 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CLFLPBHK_00838 2.48e-262 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CLFLPBHK_00839 3.12e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
CLFLPBHK_00840 2.14e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLFLPBHK_00842 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
CLFLPBHK_00843 2.91e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CLFLPBHK_00844 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
CLFLPBHK_00845 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
CLFLPBHK_00846 1.85e-58 - - - - - - - -
CLFLPBHK_00847 6.68e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
CLFLPBHK_00848 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
CLFLPBHK_00849 1.13e-13 - - - - - - - -
CLFLPBHK_00850 3.6e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
CLFLPBHK_00851 5.64e-84 iolK - - S - - - tautomerase
CLFLPBHK_00852 2.63e-73 yodB - - K - - - transcriptional
CLFLPBHK_00853 1.92e-140 yodC - - C - - - nitroreductase
CLFLPBHK_00854 2.17e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
CLFLPBHK_00855 5.61e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CLFLPBHK_00856 3.36e-38 - - - S - - - Protein of unknown function (DUF3311)
CLFLPBHK_00857 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLFLPBHK_00858 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CLFLPBHK_00859 3.03e-166 yodH - - Q - - - Methyltransferase
CLFLPBHK_00860 2.81e-40 yodI - - - - - - -
CLFLPBHK_00861 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
CLFLPBHK_00862 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
CLFLPBHK_00863 2.08e-12 - - - - - - - -
CLFLPBHK_00864 1.17e-71 yodL - - S - - - YodL-like
CLFLPBHK_00865 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
CLFLPBHK_00866 5.18e-34 yozD - - S - - - YozD-like protein
CLFLPBHK_00868 7.44e-159 yodN - - - - - - -
CLFLPBHK_00869 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
CLFLPBHK_00870 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
CLFLPBHK_00871 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
CLFLPBHK_00872 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
CLFLPBHK_00873 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
CLFLPBHK_00874 3.66e-78 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CLFLPBHK_00875 1.15e-58 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CLFLPBHK_00877 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLFLPBHK_00879 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
CLFLPBHK_00880 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
CLFLPBHK_00881 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
CLFLPBHK_00882 3.62e-82 cgeA - - - ko:K06319 - ko00000 -
CLFLPBHK_00883 4.45e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
CLFLPBHK_00884 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
CLFLPBHK_00885 5.51e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CLFLPBHK_00886 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CLFLPBHK_00887 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CLFLPBHK_00888 4.14e-94 ypoP - - K - - - transcriptional
CLFLPBHK_00889 1.65e-288 mepA - - V - - - MATE efflux family protein
CLFLPBHK_00890 1.24e-39 ypmT - - S - - - Uncharacterized ympT
CLFLPBHK_00891 4.59e-127 ypmS - - S - - - protein conserved in bacteria
CLFLPBHK_00892 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
CLFLPBHK_00893 1.24e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CLFLPBHK_00894 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
CLFLPBHK_00895 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CLFLPBHK_00896 5.47e-234 yplP - - K - - - Transcriptional regulator
CLFLPBHK_00897 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
CLFLPBHK_00898 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CLFLPBHK_00899 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CLFLPBHK_00900 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
CLFLPBHK_00901 2.01e-147 ypjP - - S - - - YpjP-like protein
CLFLPBHK_00902 5.05e-186 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
CLFLPBHK_00903 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
CLFLPBHK_00904 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
CLFLPBHK_00905 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
CLFLPBHK_00906 7.22e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
CLFLPBHK_00907 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
CLFLPBHK_00908 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CLFLPBHK_00909 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CLFLPBHK_00910 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
CLFLPBHK_00911 1.17e-22 degR - - - - - - -
CLFLPBHK_00912 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
CLFLPBHK_00913 1.54e-37 ypeQ - - S - - - Zinc-finger
CLFLPBHK_00914 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
CLFLPBHK_00915 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CLFLPBHK_00916 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
CLFLPBHK_00917 2.59e-05 - - - - ko:K06429 - ko00000 -
CLFLPBHK_00918 2.26e-213 ypcP - - L - - - 5'3' exonuclease
CLFLPBHK_00919 1.08e-11 - - - - - - - -
CLFLPBHK_00920 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
CLFLPBHK_00921 0.0 ypbR - - S - - - Dynamin family
CLFLPBHK_00922 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
CLFLPBHK_00923 4.08e-41 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
CLFLPBHK_00924 1.49e-201 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
CLFLPBHK_00925 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
CLFLPBHK_00926 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CLFLPBHK_00927 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CLFLPBHK_00928 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CLFLPBHK_00929 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
CLFLPBHK_00930 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
CLFLPBHK_00931 2.24e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
CLFLPBHK_00932 7.26e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CLFLPBHK_00933 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_00934 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
CLFLPBHK_00936 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CLFLPBHK_00937 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CLFLPBHK_00938 1.39e-127 ypsA - - S - - - Belongs to the UPF0398 family
CLFLPBHK_00939 2.81e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
CLFLPBHK_00940 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CLFLPBHK_00941 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
CLFLPBHK_00942 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CLFLPBHK_00943 8.36e-66 yppG - - S - - - YppG-like protein
CLFLPBHK_00944 9.21e-11 - - - S - - - YppF-like protein
CLFLPBHK_00945 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
CLFLPBHK_00948 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
CLFLPBHK_00949 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CLFLPBHK_00950 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CLFLPBHK_00951 1.43e-121 ypoC - - - - - - -
CLFLPBHK_00952 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CLFLPBHK_00953 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
CLFLPBHK_00954 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
CLFLPBHK_00955 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CLFLPBHK_00956 2.66e-102 ypmB - - S - - - protein conserved in bacteria
CLFLPBHK_00957 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
CLFLPBHK_00958 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CLFLPBHK_00959 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CLFLPBHK_00960 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CLFLPBHK_00961 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CLFLPBHK_00962 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CLFLPBHK_00963 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CLFLPBHK_00964 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
CLFLPBHK_00965 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
CLFLPBHK_00966 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
CLFLPBHK_00967 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CLFLPBHK_00968 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
CLFLPBHK_00969 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CLFLPBHK_00970 6.56e-181 ypjB - - S - - - sporulation protein
CLFLPBHK_00971 1.15e-125 ypjA - - S - - - membrane
CLFLPBHK_00972 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
CLFLPBHK_00973 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
CLFLPBHK_00974 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
CLFLPBHK_00975 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
CLFLPBHK_00976 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
CLFLPBHK_00977 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
CLFLPBHK_00978 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CLFLPBHK_00979 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
CLFLPBHK_00980 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CLFLPBHK_00981 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CLFLPBHK_00982 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CLFLPBHK_00983 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
CLFLPBHK_00984 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
CLFLPBHK_00985 2.37e-227 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CLFLPBHK_00986 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLFLPBHK_00987 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CLFLPBHK_00988 3.86e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CLFLPBHK_00989 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CLFLPBHK_00990 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
CLFLPBHK_00991 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CLFLPBHK_00992 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CLFLPBHK_00993 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CLFLPBHK_00994 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CLFLPBHK_00995 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CLFLPBHK_00996 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
CLFLPBHK_00997 2.63e-11 - - - - - - - -
CLFLPBHK_00998 1e-89 - - - S - - - Phage terminase, small subunit
CLFLPBHK_00999 4.68e-273 - - - S - - - Phage Terminase
CLFLPBHK_01000 2.58e-14 - - - - - - - -
CLFLPBHK_01001 4.77e-273 - - - S - - - Phage portal protein
CLFLPBHK_01002 9.36e-135 - - - S - - - peptidase activity
CLFLPBHK_01003 3.43e-227 - - - S - - - capsid protein
CLFLPBHK_01004 8.02e-09 - - - S - - - peptidoglycan catabolic process
CLFLPBHK_01005 1.23e-39 - - - S - - - peptidoglycan catabolic process
CLFLPBHK_01006 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
CLFLPBHK_01007 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLFLPBHK_01008 1.42e-40 - - - - - - - -
CLFLPBHK_01009 9.75e-79 - - - - - - - -
CLFLPBHK_01010 1.58e-36 - - - - - - - -
CLFLPBHK_01011 4.09e-16 - - - - - - - -
CLFLPBHK_01012 0.0 - - - S - - - peptidoglycan catabolic process
CLFLPBHK_01013 1.96e-141 - - - S - - - Phage tail protein
CLFLPBHK_01014 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
CLFLPBHK_01015 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
CLFLPBHK_01016 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
CLFLPBHK_01017 6.82e-273 xylR - - GK - - - ROK family
CLFLPBHK_01018 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CLFLPBHK_01019 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
CLFLPBHK_01020 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
CLFLPBHK_01022 4.19e-20 ynaF - - - - - - -
CLFLPBHK_01023 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CLFLPBHK_01024 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CLFLPBHK_01025 1.19e-82 - - - S - - - CAAX protease self-immunity
CLFLPBHK_01026 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CLFLPBHK_01027 4.98e-106 yoaW - - - - - - -
CLFLPBHK_01028 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CLFLPBHK_01029 4.82e-69 ynaF - - - - - - -
CLFLPBHK_01031 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CLFLPBHK_01033 0.0 - - - V - - - Beta-lactamase
CLFLPBHK_01036 3.22e-61 - - - S - - - dUTPase
CLFLPBHK_01039 1.21e-32 yqaO - - S - - - Phage-like element PBSX protein XtrA
CLFLPBHK_01041 4.49e-71 - - - S - - - Protein of unknown function (DUF1064)
CLFLPBHK_01042 9.25e-32 - - - S - - - YopX protein
CLFLPBHK_01044 1.63e-106 - - - - - - - -
CLFLPBHK_01046 9.39e-123 - - - S - - - ERCC4 domain
CLFLPBHK_01047 5.17e-99 - - - - - - - -
CLFLPBHK_01049 0.0 - - - S ko:K06919 - ko00000 D5 N terminal like
CLFLPBHK_01050 1.17e-95 - - - S - - - Protein of unknown function (DUF669)
CLFLPBHK_01051 4.58e-07 - - - - - - - -
CLFLPBHK_01052 6.21e-214 - - - S - - - AAA domain
CLFLPBHK_01053 3.62e-118 - - - S - - - DNA protection
CLFLPBHK_01055 1.08e-29 - - - S - - - Uncharacterized protein YqaH
CLFLPBHK_01057 2.23e-26 - - - - - - - -
CLFLPBHK_01058 1.4e-28 - - - - - - - -
CLFLPBHK_01059 3.84e-70 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLFLPBHK_01060 2.91e-79 - - - E - - - IrrE N-terminal-like domain
CLFLPBHK_01061 2.28e-143 - - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_01062 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CLFLPBHK_01063 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CLFLPBHK_01064 2.51e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CLFLPBHK_01065 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLFLPBHK_01066 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLFLPBHK_01067 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CLFLPBHK_01068 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CLFLPBHK_01069 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLFLPBHK_01070 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CLFLPBHK_01071 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CLFLPBHK_01072 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CLFLPBHK_01073 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CLFLPBHK_01074 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CLFLPBHK_01075 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CLFLPBHK_01076 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CLFLPBHK_01077 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CLFLPBHK_01078 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CLFLPBHK_01079 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CLFLPBHK_01080 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CLFLPBHK_01081 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CLFLPBHK_01082 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CLFLPBHK_01083 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLFLPBHK_01084 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CLFLPBHK_01085 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CLFLPBHK_01086 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CLFLPBHK_01087 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CLFLPBHK_01088 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CLFLPBHK_01089 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CLFLPBHK_01090 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CLFLPBHK_01091 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CLFLPBHK_01092 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CLFLPBHK_01093 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CLFLPBHK_01094 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CLFLPBHK_01095 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CLFLPBHK_01096 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CLFLPBHK_01097 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CLFLPBHK_01098 1.83e-230 ybaC - - S - - - Alpha/beta hydrolase family
CLFLPBHK_01099 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CLFLPBHK_01100 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CLFLPBHK_01101 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CLFLPBHK_01102 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CLFLPBHK_01103 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
CLFLPBHK_01104 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLFLPBHK_01105 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CLFLPBHK_01106 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
CLFLPBHK_01107 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CLFLPBHK_01108 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CLFLPBHK_01109 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CLFLPBHK_01110 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CLFLPBHK_01111 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CLFLPBHK_01112 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CLFLPBHK_01113 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
CLFLPBHK_01114 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
CLFLPBHK_01115 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLFLPBHK_01116 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CLFLPBHK_01117 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CLFLPBHK_01118 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
CLFLPBHK_01119 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CLFLPBHK_01120 1.82e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CLFLPBHK_01121 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CLFLPBHK_01122 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
CLFLPBHK_01123 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CLFLPBHK_01124 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CLFLPBHK_01125 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
CLFLPBHK_01126 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CLFLPBHK_01127 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
CLFLPBHK_01128 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
CLFLPBHK_01129 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLFLPBHK_01130 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CLFLPBHK_01131 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
CLFLPBHK_01132 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CLFLPBHK_01133 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
CLFLPBHK_01134 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CLFLPBHK_01135 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CLFLPBHK_01136 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CLFLPBHK_01137 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CLFLPBHK_01138 4.32e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
CLFLPBHK_01139 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CLFLPBHK_01140 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CLFLPBHK_01141 8.33e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CLFLPBHK_01142 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CLFLPBHK_01143 3.77e-97 - - - S - - - Bacterial PH domain
CLFLPBHK_01144 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
CLFLPBHK_01145 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CLFLPBHK_01146 9.33e-108 - - - S - - - Protein of unknown function (DUF3800)
CLFLPBHK_01150 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CLFLPBHK_01151 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
CLFLPBHK_01152 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_01153 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CLFLPBHK_01154 2.51e-13 - - - - - - - -
CLFLPBHK_01156 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CLFLPBHK_01157 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
CLFLPBHK_01158 3.81e-275 ywfA - - EGP - - - -transporter
CLFLPBHK_01159 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CLFLPBHK_01160 0.0 rocB - - E - - - arginine degradation protein
CLFLPBHK_01161 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CLFLPBHK_01162 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CLFLPBHK_01163 3.7e-101 - - - - - - - -
CLFLPBHK_01164 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
CLFLPBHK_01165 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CLFLPBHK_01166 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CLFLPBHK_01167 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CLFLPBHK_01168 4.71e-239 spsG - - M - - - Spore Coat
CLFLPBHK_01169 2.47e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
CLFLPBHK_01170 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
CLFLPBHK_01171 2.01e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
CLFLPBHK_01172 3.06e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
CLFLPBHK_01173 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
CLFLPBHK_01174 8.08e-187 spsA - - M - - - Spore Coat
CLFLPBHK_01175 3.7e-106 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CLFLPBHK_01176 1.59e-78 ywdK - - S - - - small membrane protein
CLFLPBHK_01177 1.86e-303 ywdJ - - F - - - Xanthine uracil
CLFLPBHK_01178 1.26e-62 ywdI - - S - - - Family of unknown function (DUF5327)
CLFLPBHK_01179 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CLFLPBHK_01180 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CLFLPBHK_01181 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
CLFLPBHK_01182 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CLFLPBHK_01183 6.19e-39 ywdA - - - - - - -
CLFLPBHK_01184 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CLFLPBHK_01185 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_01186 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
CLFLPBHK_01187 3.69e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CLFLPBHK_01189 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CLFLPBHK_01190 2.6e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLFLPBHK_01191 1.9e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
CLFLPBHK_01192 2.19e-174 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CLFLPBHK_01194 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
CLFLPBHK_01195 1.3e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CLFLPBHK_01196 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CLFLPBHK_01197 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLFLPBHK_01198 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CLFLPBHK_01199 5.11e-49 ydaS - - S - - - membrane
CLFLPBHK_01200 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CLFLPBHK_01201 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CLFLPBHK_01202 3.33e-77 gtcA - - S - - - GtrA-like protein
CLFLPBHK_01203 1.98e-157 ywcC - - K - - - transcriptional regulator
CLFLPBHK_01205 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
CLFLPBHK_01206 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLFLPBHK_01207 1.47e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CLFLPBHK_01208 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
CLFLPBHK_01209 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
CLFLPBHK_01210 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
CLFLPBHK_01211 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CLFLPBHK_01212 5.39e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CLFLPBHK_01213 1.28e-201 ywbI - - K - - - Transcriptional regulator
CLFLPBHK_01214 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CLFLPBHK_01215 1.21e-143 ywbG - - M - - - effector of murein hydrolase
CLFLPBHK_01216 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
CLFLPBHK_01217 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
CLFLPBHK_01218 1.28e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
CLFLPBHK_01219 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
CLFLPBHK_01220 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
CLFLPBHK_01221 1.81e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLFLPBHK_01222 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CLFLPBHK_01223 4.43e-307 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_01224 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CLFLPBHK_01225 5.37e-216 gspA - - M - - - General stress
CLFLPBHK_01226 3.49e-158 ywaF - - S - - - Integral membrane protein
CLFLPBHK_01227 1.25e-114 ywaE - - K - - - Transcriptional regulator
CLFLPBHK_01228 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CLFLPBHK_01229 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
CLFLPBHK_01230 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
CLFLPBHK_01231 7.55e-59 orfX1 - - L - - - Transposase
CLFLPBHK_01232 5.6e-173 - - - L - - - Integrase core domain
CLFLPBHK_01233 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CLFLPBHK_01234 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CLFLPBHK_01235 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
CLFLPBHK_01236 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CLFLPBHK_01237 0.0 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
CLFLPBHK_01238 2.19e-86 - - - - ko:K19174 - ko00000,ko02048 -
CLFLPBHK_01239 3.83e-131 - - - V ko:K19173 - ko00000,ko02048 Type I site-specific restriction-modification system, R (Restriction) subunit and related
CLFLPBHK_01240 2.86e-193 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
CLFLPBHK_01241 8.5e-272 - - - EH ko:K19170 - ko00000,ko02048 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
CLFLPBHK_01242 3.14e-187 - - - EL ko:K19171 - ko00000,ko02048 AAA domain
CLFLPBHK_01243 1.9e-41 - - - S - - - DNA sulphur modification protein DndE
CLFLPBHK_01244 8.04e-181 - 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
CLFLPBHK_01245 1.72e-255 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
CLFLPBHK_01246 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
CLFLPBHK_01247 2.96e-245 yceH - - P - - - Belongs to the TelA family
CLFLPBHK_01248 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
CLFLPBHK_01249 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
CLFLPBHK_01250 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CLFLPBHK_01251 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CLFLPBHK_01252 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
CLFLPBHK_01253 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLFLPBHK_01254 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLFLPBHK_01255 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CLFLPBHK_01256 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CLFLPBHK_01257 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CLFLPBHK_01258 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CLFLPBHK_01259 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
CLFLPBHK_01260 1.65e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_01261 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CLFLPBHK_01262 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_01263 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_01264 6.38e-229 ycdA - - S - - - Domain of unknown function (DUF5105)
CLFLPBHK_01265 4.58e-68 yccK - - C - - - Aldo keto reductase
CLFLPBHK_01266 2.9e-28 yccK - - C - - - Aldo keto reductase
CLFLPBHK_01267 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_01268 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
CLFLPBHK_01269 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
CLFLPBHK_01270 6.18e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
CLFLPBHK_01271 7.13e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
CLFLPBHK_01272 4.32e-78 - - - S - - - RDD family
CLFLPBHK_01273 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLFLPBHK_01274 8.02e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CLFLPBHK_01275 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CLFLPBHK_01276 1.45e-301 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
CLFLPBHK_01277 1.39e-258 ycbU - - E - - - Selenocysteine lyase
CLFLPBHK_01278 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CLFLPBHK_01279 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLFLPBHK_01280 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CLFLPBHK_01281 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
CLFLPBHK_01282 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
CLFLPBHK_01284 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CLFLPBHK_01285 9.39e-63 yhcM - - - - - - -
CLFLPBHK_01287 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_01288 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
CLFLPBHK_01289 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
CLFLPBHK_01290 3.19e-111 yddI - - - - - - -
CLFLPBHK_01291 1.03e-237 yddH - - M - - - Lysozyme-like
CLFLPBHK_01292 0.0 yddG - - S - - - maturation of SSU-rRNA
CLFLPBHK_01293 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
CLFLPBHK_01294 2.21e-242 yddE - - S - - - AAA-like domain
CLFLPBHK_01295 1.59e-270 yddE - - S - - - AAA-like domain
CLFLPBHK_01296 6.91e-118 yddD - - S - - - TcpE family
CLFLPBHK_01297 9.78e-54 yddC - - - - - - -
CLFLPBHK_01298 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
CLFLPBHK_01302 4.39e-37 yddA - - - - - - -
CLFLPBHK_01304 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_01308 1.5e-81 - - - S - - - Immunity protein 70
CLFLPBHK_01309 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
CLFLPBHK_01310 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLFLPBHK_01311 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
CLFLPBHK_01312 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CLFLPBHK_01313 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
CLFLPBHK_01314 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CLFLPBHK_01315 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_01316 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_01317 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_01318 2.06e-69 - - - - - - - -
CLFLPBHK_01319 3.95e-59 yhcC - - - - - - -
CLFLPBHK_01320 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
CLFLPBHK_01321 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
CLFLPBHK_01322 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
CLFLPBHK_01323 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
CLFLPBHK_01324 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
CLFLPBHK_01325 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
CLFLPBHK_01326 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CLFLPBHK_01327 1.53e-94 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CLFLPBHK_01328 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
CLFLPBHK_01329 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CLFLPBHK_01330 9.27e-224 yhbB - - S - - - Putative amidase domain
CLFLPBHK_01331 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CLFLPBHK_01332 1.07e-144 yhzB - - S - - - B3/4 domain
CLFLPBHK_01334 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_01335 6.32e-99 ygaO - - - - - - -
CLFLPBHK_01336 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CLFLPBHK_01339 2.57e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
CLFLPBHK_01340 4.62e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CLFLPBHK_01341 2.79e-213 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
CLFLPBHK_01342 7.4e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CLFLPBHK_01343 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CLFLPBHK_01345 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CLFLPBHK_01346 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
CLFLPBHK_01347 1.58e-36 - - - - - - - -
CLFLPBHK_01348 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
CLFLPBHK_01350 0.0 yclG - - M - - - Pectate lyase superfamily protein
CLFLPBHK_01351 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
CLFLPBHK_01352 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
CLFLPBHK_01353 6.45e-55 yclD - - - - - - -
CLFLPBHK_01354 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
CLFLPBHK_01355 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CLFLPBHK_01356 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CLFLPBHK_01357 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
CLFLPBHK_01358 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
CLFLPBHK_01359 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CLFLPBHK_01360 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CLFLPBHK_01361 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
CLFLPBHK_01362 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
CLFLPBHK_01363 0.0 ycxD - - K - - - GntR family transcriptional regulator
CLFLPBHK_01364 1.17e-198 ycxC - - EG - - - EamA-like transporter family
CLFLPBHK_01365 1.48e-122 - - - S - - - YcxB-like protein
CLFLPBHK_01366 4.92e-285 - - - EGP - - - Major Facilitator Superfamily
CLFLPBHK_01367 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
CLFLPBHK_01368 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
CLFLPBHK_01369 1.96e-302 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_01370 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
CLFLPBHK_01371 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
CLFLPBHK_01372 7.34e-66 yqgV - - S - - - Thiamine-binding protein
CLFLPBHK_01373 2.69e-256 yqgU - - - - - - -
CLFLPBHK_01374 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
CLFLPBHK_01375 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CLFLPBHK_01376 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
CLFLPBHK_01377 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
CLFLPBHK_01378 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
CLFLPBHK_01379 3.38e-14 yqgO - - - - - - -
CLFLPBHK_01380 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CLFLPBHK_01381 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CLFLPBHK_01382 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
CLFLPBHK_01384 2.81e-67 yqzD - - - - - - -
CLFLPBHK_01385 1.09e-93 yqzC - - S - - - YceG-like family
CLFLPBHK_01386 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLFLPBHK_01387 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CLFLPBHK_01388 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
CLFLPBHK_01389 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CLFLPBHK_01390 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CLFLPBHK_01391 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
CLFLPBHK_01392 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
CLFLPBHK_01393 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
CLFLPBHK_01394 2.36e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
CLFLPBHK_01395 1.12e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
CLFLPBHK_01396 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
CLFLPBHK_01397 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CLFLPBHK_01398 2.38e-80 yqfX - - S - - - membrane
CLFLPBHK_01399 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
CLFLPBHK_01400 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
CLFLPBHK_01401 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CLFLPBHK_01402 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
CLFLPBHK_01403 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CLFLPBHK_01404 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CLFLPBHK_01405 1.05e-48 yqfQ - - S - - - YqfQ-like protein
CLFLPBHK_01406 1.01e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CLFLPBHK_01407 7.29e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CLFLPBHK_01408 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CLFLPBHK_01409 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CLFLPBHK_01410 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CLFLPBHK_01411 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CLFLPBHK_01412 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
CLFLPBHK_01413 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CLFLPBHK_01414 3.29e-144 ccpN - - K - - - CBS domain
CLFLPBHK_01415 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CLFLPBHK_01416 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CLFLPBHK_01417 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CLFLPBHK_01418 5.29e-27 - - - S - - - YqzL-like protein
CLFLPBHK_01419 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CLFLPBHK_01420 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CLFLPBHK_01421 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
CLFLPBHK_01422 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CLFLPBHK_01423 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
CLFLPBHK_01425 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
CLFLPBHK_01426 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
CLFLPBHK_01427 2.07e-60 yqfC - - S - - - sporulation protein YqfC
CLFLPBHK_01428 2.23e-56 yqfB - - - - - - -
CLFLPBHK_01429 4.35e-192 yqfA - - S - - - UPF0365 protein
CLFLPBHK_01430 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
CLFLPBHK_01431 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
CLFLPBHK_01432 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CLFLPBHK_01433 4.64e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
CLFLPBHK_01434 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
CLFLPBHK_01435 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CLFLPBHK_01436 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
CLFLPBHK_01437 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CLFLPBHK_01438 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CLFLPBHK_01439 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CLFLPBHK_01440 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CLFLPBHK_01441 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
CLFLPBHK_01442 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CLFLPBHK_01443 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
CLFLPBHK_01444 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
CLFLPBHK_01445 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CLFLPBHK_01446 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CLFLPBHK_01447 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CLFLPBHK_01448 2.36e-22 - - - S - - - YqzM-like protein
CLFLPBHK_01449 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CLFLPBHK_01450 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
CLFLPBHK_01451 3.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
CLFLPBHK_01452 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLFLPBHK_01453 7.73e-176 yqeM - - Q - - - Methyltransferase
CLFLPBHK_01454 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CLFLPBHK_01455 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
CLFLPBHK_01456 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CLFLPBHK_01457 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
CLFLPBHK_01458 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CLFLPBHK_01459 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CLFLPBHK_01460 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
CLFLPBHK_01462 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
CLFLPBHK_01463 2.3e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_01464 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
CLFLPBHK_01465 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
CLFLPBHK_01466 7.4e-168 - - - - - - - -
CLFLPBHK_01467 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
CLFLPBHK_01468 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_01469 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CLFLPBHK_01470 1.14e-197 yybE - - K - - - Transcriptional regulator
CLFLPBHK_01471 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
CLFLPBHK_01473 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
CLFLPBHK_01474 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CLFLPBHK_01475 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
CLFLPBHK_01476 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
CLFLPBHK_01478 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
CLFLPBHK_01479 1.1e-20 - - - S - - - SMI1 / KNR4 family
CLFLPBHK_01480 5.24e-60 - - - - - - - -
CLFLPBHK_01484 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
CLFLPBHK_01485 1.89e-40 - - - - - - - -
CLFLPBHK_01486 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
CLFLPBHK_01487 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CLFLPBHK_01488 1.39e-257 yaaN - - P - - - Belongs to the TelA family
CLFLPBHK_01489 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
CLFLPBHK_01490 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CLFLPBHK_01491 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
CLFLPBHK_01492 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
CLFLPBHK_01493 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CLFLPBHK_01494 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
CLFLPBHK_01495 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
CLFLPBHK_01496 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
CLFLPBHK_01497 2.84e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
CLFLPBHK_01498 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CLFLPBHK_01499 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
CLFLPBHK_01500 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CLFLPBHK_01501 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
CLFLPBHK_01502 1.18e-277 yabE - - T - - - protein conserved in bacteria
CLFLPBHK_01503 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CLFLPBHK_01504 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CLFLPBHK_01505 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
CLFLPBHK_01506 5.32e-53 veg - - S - - - protein conserved in bacteria
CLFLPBHK_01507 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
CLFLPBHK_01508 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CLFLPBHK_01509 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CLFLPBHK_01510 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
CLFLPBHK_01511 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CLFLPBHK_01512 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CLFLPBHK_01513 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CLFLPBHK_01514 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CLFLPBHK_01515 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CLFLPBHK_01516 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
CLFLPBHK_01517 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CLFLPBHK_01518 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
CLFLPBHK_01519 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_01520 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CLFLPBHK_01521 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CLFLPBHK_01522 1.91e-66 yabP - - S - - - Sporulation protein YabP
CLFLPBHK_01523 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
CLFLPBHK_01524 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CLFLPBHK_01525 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CLFLPBHK_01528 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
CLFLPBHK_01529 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CLFLPBHK_01530 6.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
CLFLPBHK_01531 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CLFLPBHK_01532 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
CLFLPBHK_01533 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CLFLPBHK_01534 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CLFLPBHK_01535 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CLFLPBHK_01536 2.41e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
CLFLPBHK_01537 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CLFLPBHK_01538 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
CLFLPBHK_01541 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
CLFLPBHK_01542 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
CLFLPBHK_01543 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CLFLPBHK_01544 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CLFLPBHK_01545 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
CLFLPBHK_01546 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
CLFLPBHK_01547 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CLFLPBHK_01548 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLFLPBHK_01549 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLFLPBHK_01550 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_01551 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_01552 2.1e-253 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
CLFLPBHK_01553 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
CLFLPBHK_01554 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CLFLPBHK_01555 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
CLFLPBHK_01557 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
CLFLPBHK_01558 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
CLFLPBHK_01559 4.28e-163 - - - - - - - -
CLFLPBHK_01560 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CLFLPBHK_01561 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
CLFLPBHK_01562 1.24e-156 ydhC - - K - - - FCD
CLFLPBHK_01563 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
CLFLPBHK_01564 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
CLFLPBHK_01565 1.9e-89 - - - K - - - Winged helix DNA-binding domain
CLFLPBHK_01566 6.42e-147 ydgI - - C - - - nitroreductase
CLFLPBHK_01567 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
CLFLPBHK_01568 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CLFLPBHK_01569 6.94e-117 - - - S - - - DinB family
CLFLPBHK_01570 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_01571 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
CLFLPBHK_01572 8.04e-111 yycN - - K - - - Acetyltransferase
CLFLPBHK_01573 5.76e-70 - - - S - - - DoxX-like family
CLFLPBHK_01574 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
CLFLPBHK_01575 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
CLFLPBHK_01576 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
CLFLPBHK_01577 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CLFLPBHK_01578 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_01579 5e-152 ydfR - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_01581 3.75e-39 - - - - - - - -
CLFLPBHK_01582 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
CLFLPBHK_01583 2.1e-71 ydfQ - - CO - - - Thioredoxin
CLFLPBHK_01584 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
CLFLPBHK_01585 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CLFLPBHK_01586 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
CLFLPBHK_01587 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLFLPBHK_01588 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
CLFLPBHK_01589 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
CLFLPBHK_01590 4.26e-220 - - - S - - - Alpha/beta hydrolase family
CLFLPBHK_01592 3.38e-216 yhcP - - - - - - -
CLFLPBHK_01593 8.21e-123 yhcQ - - M - - - Spore coat protein
CLFLPBHK_01594 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CLFLPBHK_01595 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
CLFLPBHK_01596 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CLFLPBHK_01597 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
CLFLPBHK_01598 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
CLFLPBHK_01599 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
CLFLPBHK_01600 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CLFLPBHK_01601 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CLFLPBHK_01602 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CLFLPBHK_01603 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CLFLPBHK_01604 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CLFLPBHK_01605 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CLFLPBHK_01606 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
CLFLPBHK_01607 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_01608 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_01609 1.9e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
CLFLPBHK_01610 1.65e-51 yhdB - - S - - - YhdB-like protein
CLFLPBHK_01611 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
CLFLPBHK_01612 1.32e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CLFLPBHK_01613 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
CLFLPBHK_01614 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
CLFLPBHK_01615 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
CLFLPBHK_01616 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
CLFLPBHK_01617 1.15e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
CLFLPBHK_01618 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
CLFLPBHK_01619 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_01620 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
CLFLPBHK_01621 1.53e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
CLFLPBHK_01622 1.03e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
CLFLPBHK_01623 8.14e-128 - - - G ko:K03292 - ko00000 symporter YjmB
CLFLPBHK_01624 1.13e-165 - - - G ko:K03292 - ko00000 symporter YjmB
CLFLPBHK_01625 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
CLFLPBHK_01626 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CLFLPBHK_01627 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
CLFLPBHK_01628 4.85e-54 yjlB - - S - - - Cupin domain
CLFLPBHK_01629 1.26e-20 yjlB - - S - - - Cupin domain
CLFLPBHK_01630 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
CLFLPBHK_01631 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CLFLPBHK_01632 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
CLFLPBHK_01633 4.71e-122 rok - - K - - - Repressor of ComK
CLFLPBHK_01634 4.23e-104 ykuV - - CO - - - thiol-disulfide
CLFLPBHK_01635 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
CLFLPBHK_01636 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
CLFLPBHK_01637 3.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CLFLPBHK_01639 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CLFLPBHK_01640 4.29e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CLFLPBHK_01641 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_01642 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLFLPBHK_01643 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
CLFLPBHK_01644 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_01645 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
CLFLPBHK_01646 2.25e-59 ybfN - - - - - - -
CLFLPBHK_01647 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CLFLPBHK_01648 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
CLFLPBHK_01649 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLFLPBHK_01650 1.31e-212 - - - S - - - Alpha/beta hydrolase family
CLFLPBHK_01652 3.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
CLFLPBHK_01653 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CLFLPBHK_01654 2.61e-73 - - - - - - - -
CLFLPBHK_01655 4.74e-185 - - GH19 M ko:K03791 - ko00000 Lysin motif
CLFLPBHK_01656 2.73e-28 xhlB - - S - - - SPP1 phage holin
CLFLPBHK_01657 3.63e-43 - - - K - - - sigma factor activity
CLFLPBHK_01658 2.88e-185 ybfI - - K - - - AraC-like ligand binding domain
CLFLPBHK_01659 5.01e-133 ybfH - - EG - - - EamA-like transporter family
CLFLPBHK_01660 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
CLFLPBHK_01663 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_01664 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_01665 8.65e-202 ybfA - - K - - - FR47-like protein
CLFLPBHK_01666 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
CLFLPBHK_01667 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
CLFLPBHK_01668 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
CLFLPBHK_01669 0.0 ybeC - - E - - - amino acid
CLFLPBHK_01670 1.28e-37 ybyB - - - - - - -
CLFLPBHK_01671 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
CLFLPBHK_01672 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
CLFLPBHK_01673 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
CLFLPBHK_01674 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
CLFLPBHK_01676 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
CLFLPBHK_01677 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CLFLPBHK_01678 5.44e-74 yuzD - - S - - - protein conserved in bacteria
CLFLPBHK_01679 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
CLFLPBHK_01680 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
CLFLPBHK_01681 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CLFLPBHK_01682 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CLFLPBHK_01683 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CLFLPBHK_01684 2.57e-252 yutH - - S - - - Spore coat protein
CLFLPBHK_01685 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
CLFLPBHK_01686 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CLFLPBHK_01687 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
CLFLPBHK_01688 3.2e-63 yutD - - S - - - protein conserved in bacteria
CLFLPBHK_01689 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CLFLPBHK_01690 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CLFLPBHK_01691 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
CLFLPBHK_01692 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
CLFLPBHK_01693 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
CLFLPBHK_01694 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CLFLPBHK_01695 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
CLFLPBHK_01696 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
CLFLPBHK_01697 1.07e-79 yunG - - - - - - -
CLFLPBHK_01698 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CLFLPBHK_01699 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
CLFLPBHK_01700 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
CLFLPBHK_01701 4.37e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
CLFLPBHK_01702 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CLFLPBHK_01703 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CLFLPBHK_01705 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CLFLPBHK_01706 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CLFLPBHK_01707 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CLFLPBHK_01708 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CLFLPBHK_01709 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
CLFLPBHK_01710 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CLFLPBHK_01711 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CLFLPBHK_01712 4.82e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CLFLPBHK_01713 4.42e-216 bsn - - L - - - Ribonuclease
CLFLPBHK_01714 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_01715 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CLFLPBHK_01716 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
CLFLPBHK_01717 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CLFLPBHK_01718 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CLFLPBHK_01719 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CLFLPBHK_01720 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
CLFLPBHK_01721 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CLFLPBHK_01722 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
CLFLPBHK_01723 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
CLFLPBHK_01725 3.35e-56 - - - - - - - -
CLFLPBHK_01728 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CLFLPBHK_01729 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
CLFLPBHK_01730 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
CLFLPBHK_01731 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CLFLPBHK_01732 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CLFLPBHK_01733 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
CLFLPBHK_01734 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CLFLPBHK_01735 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CLFLPBHK_01736 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CLFLPBHK_01737 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CLFLPBHK_01738 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
CLFLPBHK_01739 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
CLFLPBHK_01740 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CLFLPBHK_01741 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CLFLPBHK_01742 1.91e-182 - - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_01743 2.71e-61 xkdA - - E - - - IrrE N-terminal-like domain
CLFLPBHK_01744 6.71e-28 - - - K - - - transcriptional
CLFLPBHK_01745 1.5e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_01746 1.68e-48 - - - - - - - -
CLFLPBHK_01747 1.22e-48 - - - S - - - DNA binding
CLFLPBHK_01748 3.14e-110 - - - - - - - -
CLFLPBHK_01753 4.18e-125 - - - - - - - -
CLFLPBHK_01754 8.58e-88 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
CLFLPBHK_01756 4.69e-96 yqaL - - L - - - DnaD domain protein
CLFLPBHK_01757 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
CLFLPBHK_01759 2.02e-81 rusA - - L - - - Endodeoxyribonuclease RusA
CLFLPBHK_01760 1.78e-34 yqaO - - S - - - Phage-like element PBSX protein XtrA
CLFLPBHK_01763 1.19e-37 - - - - - - - -
CLFLPBHK_01764 6e-147 - - - - - - - -
CLFLPBHK_01766 1.84e-105 - - - L - - - Transposase
CLFLPBHK_01767 7.11e-39 - - - - - - - -
CLFLPBHK_01768 1.19e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
CLFLPBHK_01769 5.19e-102 - - - L - - - phage terminase small subunit
CLFLPBHK_01770 0.0 - - - S - - - Terminase
CLFLPBHK_01772 2.64e-303 - - - S - - - Phage portal protein
CLFLPBHK_01773 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
CLFLPBHK_01774 1.06e-266 - - - S - - - capsid protein
CLFLPBHK_01775 1.89e-34 - - - - - - - -
CLFLPBHK_01776 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
CLFLPBHK_01777 5.23e-52 - - - S - - - Phage head-tail joining protein
CLFLPBHK_01778 8.4e-67 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLFLPBHK_01780 1.67e-101 - - - N - - - Phage major tail protein phi13
CLFLPBHK_01781 1.77e-05 - - - - - - - -
CLFLPBHK_01783 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
CLFLPBHK_01784 1.08e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_01785 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
CLFLPBHK_01788 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
CLFLPBHK_01791 2.43e-14 - - - - - - - -
CLFLPBHK_01792 3.59e-26 xkdM - - S - - - Phage tail tube protein
CLFLPBHK_01794 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
CLFLPBHK_01795 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_01796 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_01798 1.15e-20 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLFLPBHK_01799 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CLFLPBHK_01800 4.04e-149 ydfE - - S - - - Flavin reductase like domain
CLFLPBHK_01801 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
CLFLPBHK_01802 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_01803 9.99e-197 - - - EG - - - EamA-like transporter family
CLFLPBHK_01804 8.66e-186 - - - J - - - GNAT acetyltransferase
CLFLPBHK_01805 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLFLPBHK_01806 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
CLFLPBHK_01807 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CLFLPBHK_01808 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
CLFLPBHK_01809 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
CLFLPBHK_01810 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
CLFLPBHK_01811 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_01812 4.66e-197 ydeK - - EG - - - -transporter
CLFLPBHK_01813 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
CLFLPBHK_01814 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
CLFLPBHK_01815 2.4e-41 - - - S - - - SNARE associated Golgi protein
CLFLPBHK_01816 4.95e-140 - - - - - - - -
CLFLPBHK_01817 4.72e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
CLFLPBHK_01818 1.34e-196 ydeG - - EGP - - - Major facilitator superfamily
CLFLPBHK_01819 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_01820 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
CLFLPBHK_01821 2.27e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CLFLPBHK_01822 2.44e-210 - - - K - - - AraC-like ligand binding domain
CLFLPBHK_01823 1.8e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CLFLPBHK_01824 6.05e-86 hxlR - - K - - - transcriptional
CLFLPBHK_01825 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
CLFLPBHK_01826 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
CLFLPBHK_01827 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_01828 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_01829 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
CLFLPBHK_01830 3.36e-91 nin - - S - - - Competence protein J (ComJ)
CLFLPBHK_01831 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CLFLPBHK_01832 8.9e-22 - - - S - - - AAA domain
CLFLPBHK_01833 2.13e-113 - - - S - - - AAA domain
CLFLPBHK_01834 2.49e-27 - - - - - - - -
CLFLPBHK_01835 1.06e-57 - - - K - - - MarR family
CLFLPBHK_01836 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
CLFLPBHK_01837 1.11e-96 yckC - - S - - - membrane
CLFLPBHK_01840 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CLFLPBHK_01841 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CLFLPBHK_01842 2.26e-123 yciC - - S - - - GTPases (G3E family)
CLFLPBHK_01843 2.72e-141 yciC - - S - - - GTPases (G3E family)
CLFLPBHK_01844 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
CLFLPBHK_01845 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
CLFLPBHK_01846 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
CLFLPBHK_01847 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
CLFLPBHK_01848 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLFLPBHK_01849 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CLFLPBHK_01850 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
CLFLPBHK_01851 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CLFLPBHK_01852 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CLFLPBHK_01853 3.3e-200 ycgS - - I - - - alpha/beta hydrolase fold
CLFLPBHK_01854 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
CLFLPBHK_01855 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
CLFLPBHK_01856 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
CLFLPBHK_01857 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLFLPBHK_01858 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CLFLPBHK_01859 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CLFLPBHK_01860 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
CLFLPBHK_01861 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
CLFLPBHK_01862 5.64e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
CLFLPBHK_01863 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
CLFLPBHK_01864 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CLFLPBHK_01865 1.31e-140 tmrB - - S - - - AAA domain
CLFLPBHK_01866 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CLFLPBHK_01867 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
CLFLPBHK_01868 2.67e-154 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_01869 4.4e-134 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_01870 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
CLFLPBHK_01871 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CLFLPBHK_01872 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CLFLPBHK_01873 1.31e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
CLFLPBHK_01874 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
CLFLPBHK_01875 2.72e-105 ycgB - - - - - - -
CLFLPBHK_01876 0.0 ycgA - - S - - - Membrane
CLFLPBHK_01877 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
CLFLPBHK_01878 5.04e-305 ygxB - - M - - - Conserved TM helix
CLFLPBHK_01879 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
CLFLPBHK_01880 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
CLFLPBHK_01881 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CLFLPBHK_01882 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_01883 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CLFLPBHK_01884 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_01885 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
CLFLPBHK_01886 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CLFLPBHK_01887 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_01888 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_01889 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
CLFLPBHK_01890 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
CLFLPBHK_01891 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_01892 1.12e-242 yhdN - - C - - - Aldo keto reductase
CLFLPBHK_01893 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CLFLPBHK_01894 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CLFLPBHK_01895 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
CLFLPBHK_01896 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CLFLPBHK_01897 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CLFLPBHK_01898 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
CLFLPBHK_01899 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLFLPBHK_01900 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CLFLPBHK_01901 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CLFLPBHK_01902 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
CLFLPBHK_01903 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
CLFLPBHK_01904 9.4e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CLFLPBHK_01905 9.72e-192 nodB1 - - G - - - deacetylase
CLFLPBHK_01906 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CLFLPBHK_01907 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CLFLPBHK_01908 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
CLFLPBHK_01909 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CLFLPBHK_01910 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CLFLPBHK_01911 1.29e-140 yheG - - GM - - - NAD(P)H-binding
CLFLPBHK_01912 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
CLFLPBHK_01913 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
CLFLPBHK_01914 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
CLFLPBHK_01915 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
CLFLPBHK_01916 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
CLFLPBHK_01917 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
CLFLPBHK_01918 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
CLFLPBHK_01919 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
CLFLPBHK_01920 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
CLFLPBHK_01921 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
CLFLPBHK_01922 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
CLFLPBHK_01923 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CLFLPBHK_01925 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
CLFLPBHK_01926 1.89e-35 - - - S - - - YhzD-like protein
CLFLPBHK_01927 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_01928 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
CLFLPBHK_01929 8.42e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
CLFLPBHK_01930 0.0 yhaN - - L - - - AAA domain
CLFLPBHK_01931 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
CLFLPBHK_01932 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
CLFLPBHK_01933 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CLFLPBHK_01934 4.72e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CLFLPBHK_01935 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CLFLPBHK_01936 9.7e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CLFLPBHK_01937 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CLFLPBHK_01938 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CLFLPBHK_01939 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CLFLPBHK_01940 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
CLFLPBHK_01941 1.61e-81 ylbA - - S - - - YugN-like family
CLFLPBHK_01942 1.53e-97 ylbB - - T - - - COG0517 FOG CBS domain
CLFLPBHK_01943 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
CLFLPBHK_01944 3.78e-88 ylbD - - S - - - Putative coat protein
CLFLPBHK_01945 1.73e-48 ylbE - - S - - - YlbE-like protein
CLFLPBHK_01946 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
CLFLPBHK_01947 4.36e-52 ylbG - - S - - - UPF0298 protein
CLFLPBHK_01948 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
CLFLPBHK_01949 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CLFLPBHK_01950 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
CLFLPBHK_01951 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CLFLPBHK_01952 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CLFLPBHK_01953 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
CLFLPBHK_01955 1.15e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
CLFLPBHK_01956 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CLFLPBHK_01957 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CLFLPBHK_01958 1.33e-115 ylbP - - K - - - n-acetyltransferase
CLFLPBHK_01959 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLFLPBHK_01960 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CLFLPBHK_01961 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CLFLPBHK_01962 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CLFLPBHK_01963 3.42e-68 ftsL - - D - - - Essential cell division protein
CLFLPBHK_01964 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CLFLPBHK_01965 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
CLFLPBHK_01966 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CLFLPBHK_01967 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CLFLPBHK_01968 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CLFLPBHK_01969 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CLFLPBHK_01970 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CLFLPBHK_01971 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
CLFLPBHK_01972 2.77e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CLFLPBHK_01973 1.35e-143 ylxW - - S - - - protein conserved in bacteria
CLFLPBHK_01974 8.67e-132 ylxX - - S - - - protein conserved in bacteria
CLFLPBHK_01975 5.37e-76 sbp - - S - - - small basic protein
CLFLPBHK_01976 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CLFLPBHK_01977 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CLFLPBHK_01978 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
CLFLPBHK_01980 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CLFLPBHK_01981 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_01982 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_01983 6.37e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CLFLPBHK_01984 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
CLFLPBHK_01985 3.58e-51 ylmC - - S - - - sporulation protein
CLFLPBHK_01986 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
CLFLPBHK_01987 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CLFLPBHK_01988 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CLFLPBHK_01989 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
CLFLPBHK_01990 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
CLFLPBHK_01991 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
CLFLPBHK_01992 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CLFLPBHK_01994 6.48e-288 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CLFLPBHK_01995 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
CLFLPBHK_01996 9.34e-176 azlC - - E - - - AzlC protein
CLFLPBHK_01997 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
CLFLPBHK_01998 2.76e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
CLFLPBHK_01999 1.74e-131 yrdC - - Q - - - Isochorismatase family
CLFLPBHK_02000 3.24e-75 - - - S - - - Protein of unknown function (DUF2568)
CLFLPBHK_02001 2.01e-118 yrdA - - S - - - DinB family
CLFLPBHK_02002 3.9e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
CLFLPBHK_02003 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CLFLPBHK_02004 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CLFLPBHK_02005 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
CLFLPBHK_02007 4.22e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CLFLPBHK_02008 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_02009 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
CLFLPBHK_02010 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CLFLPBHK_02011 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_02012 1.19e-191 - - - S - - - Alpha beta hydrolase
CLFLPBHK_02013 6.61e-80 - - - T - - - sh3 domain protein
CLFLPBHK_02014 2.92e-81 - - - T - - - sh3 domain protein
CLFLPBHK_02015 6.62e-87 - - - E - - - Glyoxalase-like domain
CLFLPBHK_02016 4.19e-50 yraG - - - ko:K06440 - ko00000 -
CLFLPBHK_02017 9.61e-84 yraF - - M - - - Spore coat protein
CLFLPBHK_02018 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CLFLPBHK_02019 6.11e-36 yraE - - - ko:K06440 - ko00000 -
CLFLPBHK_02020 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
CLFLPBHK_02021 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
CLFLPBHK_02022 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
CLFLPBHK_02023 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
CLFLPBHK_02024 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CLFLPBHK_02025 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
CLFLPBHK_02026 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CLFLPBHK_02027 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CLFLPBHK_02028 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
CLFLPBHK_02029 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
CLFLPBHK_02030 0.0 levR - - K - - - PTS system fructose IIA component
CLFLPBHK_02031 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_02032 5.63e-137 yrhP - - E - - - LysE type translocator
CLFLPBHK_02033 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
CLFLPBHK_02034 5.77e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_02035 3.51e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
CLFLPBHK_02036 2.18e-84 oatA - - I - - - Acyltransferase family
CLFLPBHK_02037 0.0 oatA - - I - - - Acyltransferase family
CLFLPBHK_02038 2.58e-58 yrhK - - S - - - YrhK-like protein
CLFLPBHK_02039 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CLFLPBHK_02040 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
CLFLPBHK_02041 4.3e-124 yrhH - - Q - - - methyltransferase
CLFLPBHK_02042 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
CLFLPBHK_02043 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
CLFLPBHK_02045 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
CLFLPBHK_02046 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
CLFLPBHK_02047 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
CLFLPBHK_02048 5.71e-48 yrhC - - S - - - YrhC-like protein
CLFLPBHK_02049 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CLFLPBHK_02050 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
CLFLPBHK_02051 3.26e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CLFLPBHK_02052 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
CLFLPBHK_02053 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
CLFLPBHK_02054 2.02e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
CLFLPBHK_02055 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
CLFLPBHK_02056 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CLFLPBHK_02057 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CLFLPBHK_02058 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
CLFLPBHK_02059 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
CLFLPBHK_02060 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
CLFLPBHK_02061 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CLFLPBHK_02062 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
CLFLPBHK_02063 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CLFLPBHK_02064 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
CLFLPBHK_02065 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CLFLPBHK_02066 1.25e-241 yrrI - - S - - - AI-2E family transporter
CLFLPBHK_02067 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CLFLPBHK_02068 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CLFLPBHK_02069 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_02070 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_02071 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CLFLPBHK_02072 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
CLFLPBHK_02073 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
CLFLPBHK_02074 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CLFLPBHK_02075 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CLFLPBHK_02080 5.52e-31 - - - M - - - ArpU family transcriptional regulator
CLFLPBHK_02081 5.89e-58 - - - L - - - Phage integrase family
CLFLPBHK_02089 2.66e-120 yebE - - S - - - UPF0316 protein
CLFLPBHK_02090 3.13e-38 yebG - - S - - - NETI protein
CLFLPBHK_02091 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CLFLPBHK_02092 1.24e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CLFLPBHK_02093 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CLFLPBHK_02094 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
CLFLPBHK_02095 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLFLPBHK_02096 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLFLPBHK_02097 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CLFLPBHK_02098 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CLFLPBHK_02099 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
CLFLPBHK_02100 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CLFLPBHK_02101 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
CLFLPBHK_02102 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
CLFLPBHK_02103 7.5e-92 - - - K - - - helix_turn_helix ASNC type
CLFLPBHK_02104 1.49e-240 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
CLFLPBHK_02105 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
CLFLPBHK_02106 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
CLFLPBHK_02107 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
CLFLPBHK_02108 6.27e-67 yerC - - S - - - protein conserved in bacteria
CLFLPBHK_02109 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
CLFLPBHK_02111 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CLFLPBHK_02112 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CLFLPBHK_02113 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CLFLPBHK_02114 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
CLFLPBHK_02115 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
CLFLPBHK_02116 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
CLFLPBHK_02117 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLFLPBHK_02118 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLFLPBHK_02119 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CLFLPBHK_02120 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CLFLPBHK_02122 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
CLFLPBHK_02124 7.22e-252 - - - I - - - Pfam Lipase (class 3)
CLFLPBHK_02125 9.96e-22 - - - - - - - -
CLFLPBHK_02126 3.86e-10 - - - S - - - Family of unknown function (DUF5316)
CLFLPBHK_02128 8.21e-15 - - - K - - - Transcriptional regulator
CLFLPBHK_02130 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CLFLPBHK_02131 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
CLFLPBHK_02132 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CLFLPBHK_02133 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
CLFLPBHK_02134 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
CLFLPBHK_02135 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CLFLPBHK_02136 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CLFLPBHK_02137 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
CLFLPBHK_02138 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
CLFLPBHK_02139 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
CLFLPBHK_02140 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
CLFLPBHK_02141 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
CLFLPBHK_02142 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CLFLPBHK_02143 1.07e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CLFLPBHK_02144 1.92e-08 - - - - - - - -
CLFLPBHK_02145 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
CLFLPBHK_02146 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
CLFLPBHK_02147 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CLFLPBHK_02148 4.16e-198 yitS - - S - - - protein conserved in bacteria
CLFLPBHK_02149 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
CLFLPBHK_02150 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
CLFLPBHK_02151 2.9e-118 - - - - - - - -
CLFLPBHK_02152 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
CLFLPBHK_02153 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
CLFLPBHK_02154 1.42e-218 - - - - - - - -
CLFLPBHK_02155 2.41e-121 - - - - - - - -
CLFLPBHK_02156 3.91e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
CLFLPBHK_02157 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
CLFLPBHK_02158 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CLFLPBHK_02159 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
CLFLPBHK_02160 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
CLFLPBHK_02161 1.52e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CLFLPBHK_02162 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
CLFLPBHK_02163 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CLFLPBHK_02164 4.27e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
CLFLPBHK_02165 9.94e-120 yisT - - S - - - DinB family
CLFLPBHK_02166 5.32e-242 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
CLFLPBHK_02167 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
CLFLPBHK_02168 1.41e-207 yisR - - K - - - Transcriptional regulator
CLFLPBHK_02169 1.01e-310 yisQ - - V - - - Mate efflux family protein
CLFLPBHK_02170 3.44e-142 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
CLFLPBHK_02171 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CLFLPBHK_02172 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
CLFLPBHK_02173 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
CLFLPBHK_02174 3.85e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CLFLPBHK_02175 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CLFLPBHK_02176 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CLFLPBHK_02177 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
CLFLPBHK_02178 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CLFLPBHK_02179 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CLFLPBHK_02180 3.76e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CLFLPBHK_02181 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
CLFLPBHK_02182 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CLFLPBHK_02183 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CLFLPBHK_02184 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CLFLPBHK_02185 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CLFLPBHK_02186 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
CLFLPBHK_02187 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
CLFLPBHK_02188 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
CLFLPBHK_02189 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
CLFLPBHK_02190 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CLFLPBHK_02191 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
CLFLPBHK_02192 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
CLFLPBHK_02193 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
CLFLPBHK_02194 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
CLFLPBHK_02195 8.41e-202 yloC - - S - - - stress-induced protein
CLFLPBHK_02196 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
CLFLPBHK_02197 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CLFLPBHK_02198 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CLFLPBHK_02199 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CLFLPBHK_02200 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLFLPBHK_02201 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CLFLPBHK_02202 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CLFLPBHK_02203 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CLFLPBHK_02204 2.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CLFLPBHK_02205 1.38e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CLFLPBHK_02206 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CLFLPBHK_02207 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CLFLPBHK_02208 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CLFLPBHK_02209 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CLFLPBHK_02210 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CLFLPBHK_02211 3.65e-78 yloU - - S - - - protein conserved in bacteria
CLFLPBHK_02212 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
CLFLPBHK_02213 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CLFLPBHK_02214 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CLFLPBHK_02215 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CLFLPBHK_02216 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CLFLPBHK_02217 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CLFLPBHK_02218 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CLFLPBHK_02219 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CLFLPBHK_02220 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CLFLPBHK_02221 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CLFLPBHK_02222 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CLFLPBHK_02223 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CLFLPBHK_02224 1.67e-114 - - - - - - - -
CLFLPBHK_02225 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CLFLPBHK_02226 1.13e-307 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CLFLPBHK_02227 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CLFLPBHK_02228 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
CLFLPBHK_02229 3.41e-80 ylqD - - S - - - YlqD protein
CLFLPBHK_02230 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CLFLPBHK_02231 1.98e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CLFLPBHK_02232 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CLFLPBHK_02233 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CLFLPBHK_02234 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLFLPBHK_02235 0.0 ylqG - - - - - - -
CLFLPBHK_02236 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
CLFLPBHK_02237 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CLFLPBHK_02238 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CLFLPBHK_02239 3.48e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
CLFLPBHK_02240 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CLFLPBHK_02241 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CLFLPBHK_02242 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
CLFLPBHK_02243 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CLFLPBHK_02244 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CLFLPBHK_02245 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CLFLPBHK_02246 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CLFLPBHK_02247 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
CLFLPBHK_02248 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
CLFLPBHK_02249 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
CLFLPBHK_02250 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CLFLPBHK_02251 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
CLFLPBHK_02252 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CLFLPBHK_02253 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
CLFLPBHK_02254 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
CLFLPBHK_02255 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
CLFLPBHK_02256 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
CLFLPBHK_02257 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
CLFLPBHK_02258 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
CLFLPBHK_02259 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CLFLPBHK_02260 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CLFLPBHK_02261 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
CLFLPBHK_02262 3.99e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
CLFLPBHK_02263 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
CLFLPBHK_02264 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
CLFLPBHK_02265 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
CLFLPBHK_02266 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLFLPBHK_02267 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CLFLPBHK_02268 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
CLFLPBHK_02269 1.81e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
CLFLPBHK_02270 1.49e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CLFLPBHK_02271 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
CLFLPBHK_02272 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
CLFLPBHK_02273 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CLFLPBHK_02274 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CLFLPBHK_02275 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_02276 6.91e-101 ylxL - - - - - - -
CLFLPBHK_02277 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CLFLPBHK_02278 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CLFLPBHK_02279 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CLFLPBHK_02280 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CLFLPBHK_02281 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CLFLPBHK_02282 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CLFLPBHK_02283 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CLFLPBHK_02284 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CLFLPBHK_02285 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CLFLPBHK_02286 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLFLPBHK_02287 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CLFLPBHK_02288 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CLFLPBHK_02289 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
CLFLPBHK_02290 6.16e-63 ylxQ - - J - - - ribosomal protein
CLFLPBHK_02291 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CLFLPBHK_02292 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
CLFLPBHK_02293 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CLFLPBHK_02294 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CLFLPBHK_02295 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CLFLPBHK_02296 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CLFLPBHK_02297 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CLFLPBHK_02298 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
CLFLPBHK_02299 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
CLFLPBHK_02300 1.53e-56 ymxH - - S - - - YlmC YmxH family
CLFLPBHK_02301 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
CLFLPBHK_02302 1.36e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CLFLPBHK_02303 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CLFLPBHK_02304 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CLFLPBHK_02305 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CLFLPBHK_02306 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLFLPBHK_02307 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
CLFLPBHK_02308 4.94e-44 - - - S - - - YlzJ-like protein
CLFLPBHK_02309 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CLFLPBHK_02310 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_02311 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02312 9.47e-299 albE - - S - - - Peptidase M16
CLFLPBHK_02313 2.37e-309 ymfH - - S - - - zinc protease
CLFLPBHK_02314 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CLFLPBHK_02315 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
CLFLPBHK_02316 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
CLFLPBHK_02317 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
CLFLPBHK_02318 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CLFLPBHK_02319 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
CLFLPBHK_02320 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CLFLPBHK_02321 1.82e-276 pbpX - - V - - - Beta-lactamase
CLFLPBHK_02322 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CLFLPBHK_02323 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
CLFLPBHK_02324 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
CLFLPBHK_02325 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CLFLPBHK_02326 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CLFLPBHK_02327 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
CLFLPBHK_02328 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
CLFLPBHK_02329 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
CLFLPBHK_02330 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
CLFLPBHK_02331 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_02332 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_02333 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_02334 4.15e-14 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_02335 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CLFLPBHK_02336 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
CLFLPBHK_02337 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
CLFLPBHK_02338 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CLFLPBHK_02339 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
CLFLPBHK_02340 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CLFLPBHK_02341 1.27e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
CLFLPBHK_02342 2e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CLFLPBHK_02343 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
CLFLPBHK_02344 2.19e-153 yxaC - - M - - - effector of murein hydrolase
CLFLPBHK_02345 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
CLFLPBHK_02346 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CLFLPBHK_02347 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02348 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CLFLPBHK_02349 5.18e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
CLFLPBHK_02350 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
CLFLPBHK_02351 1.35e-97 yxaI - - S - - - membrane protein domain
CLFLPBHK_02352 7.97e-83 - - - S - - - Family of unknown function (DUF5391)
CLFLPBHK_02353 2.54e-43 yxaI - - S - - - membrane protein domain
CLFLPBHK_02354 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CLFLPBHK_02355 6.97e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
CLFLPBHK_02356 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CLFLPBHK_02357 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CLFLPBHK_02359 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
CLFLPBHK_02360 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_02361 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_02362 1.05e-101 - - - T - - - HPP family
CLFLPBHK_02363 2.23e-17 - - - S - - - CGNR zinc finger
CLFLPBHK_02365 7.27e-55 - - - - - - - -
CLFLPBHK_02366 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
CLFLPBHK_02367 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CLFLPBHK_02368 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CLFLPBHK_02369 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CLFLPBHK_02370 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CLFLPBHK_02371 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CLFLPBHK_02372 4.99e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CLFLPBHK_02373 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
CLFLPBHK_02374 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CLFLPBHK_02375 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
CLFLPBHK_02376 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CLFLPBHK_02377 3.3e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CLFLPBHK_02378 9.37e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_02379 1.75e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_02380 8.64e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_02381 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CLFLPBHK_02382 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
CLFLPBHK_02383 1.55e-215 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_02384 9.65e-91 - - - - - - - -
CLFLPBHK_02385 7.57e-28 yxeD - - - - - - -
CLFLPBHK_02386 5.99e-41 yxeE - - - - - - -
CLFLPBHK_02389 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
CLFLPBHK_02390 4.03e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
CLFLPBHK_02391 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CLFLPBHK_02392 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_02393 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CLFLPBHK_02394 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CLFLPBHK_02395 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_02396 4.78e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
CLFLPBHK_02397 0.0 yxeQ - - S - - - MmgE/PrpD family
CLFLPBHK_02398 2.99e-249 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
CLFLPBHK_02399 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
CLFLPBHK_02400 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CLFLPBHK_02401 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CLFLPBHK_02402 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLFLPBHK_02403 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
CLFLPBHK_02404 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CLFLPBHK_02405 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CLFLPBHK_02406 1.49e-308 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CLFLPBHK_02407 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
CLFLPBHK_02408 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CLFLPBHK_02409 0.0 - - - L - - - HKD family nuclease
CLFLPBHK_02410 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
CLFLPBHK_02411 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
CLFLPBHK_02412 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
CLFLPBHK_02413 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
CLFLPBHK_02414 1.56e-53 - - - - - - - -
CLFLPBHK_02415 8.86e-317 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CLFLPBHK_02416 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
CLFLPBHK_02417 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
CLFLPBHK_02418 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_02419 5.69e-208 yxxF - - EG - - - EamA-like transporter family
CLFLPBHK_02420 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
CLFLPBHK_02421 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CLFLPBHK_02422 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CLFLPBHK_02423 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CLFLPBHK_02424 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CLFLPBHK_02425 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
CLFLPBHK_02426 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
CLFLPBHK_02427 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
CLFLPBHK_02428 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
CLFLPBHK_02429 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
CLFLPBHK_02430 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CLFLPBHK_02431 3.36e-218 alsR - - K - - - LysR substrate binding domain
CLFLPBHK_02432 8.01e-263 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CLFLPBHK_02433 1.06e-162 ywrJ - - - - - - -
CLFLPBHK_02434 3.02e-44 cotB - - - ko:K06325 - ko00000 -
CLFLPBHK_02435 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
CLFLPBHK_02436 1e-17 - - - - - - - -
CLFLPBHK_02437 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CLFLPBHK_02438 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
CLFLPBHK_02439 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CLFLPBHK_02440 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CLFLPBHK_02441 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
CLFLPBHK_02442 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
CLFLPBHK_02444 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
CLFLPBHK_02445 4.73e-209 - - - K - - - Transcriptional regulator
CLFLPBHK_02446 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CLFLPBHK_02448 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
CLFLPBHK_02449 4.93e-95 ywqJ - - S - - - Pre-toxin TG
CLFLPBHK_02450 1.3e-23 - - - - - - - -
CLFLPBHK_02451 2.5e-26 - - - - - - - -
CLFLPBHK_02452 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
CLFLPBHK_02453 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
CLFLPBHK_02455 9.48e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
CLFLPBHK_02456 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLFLPBHK_02457 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
CLFLPBHK_02458 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CLFLPBHK_02459 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
CLFLPBHK_02460 3.6e-25 - - - - - - - -
CLFLPBHK_02461 0.0 ywqB - - S - - - SWIM zinc finger
CLFLPBHK_02462 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CLFLPBHK_02463 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CLFLPBHK_02464 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CLFLPBHK_02465 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
CLFLPBHK_02466 2.79e-40 ywpG - - - - - - -
CLFLPBHK_02467 3.59e-88 ywpF - - S - - - YwpF-like protein
CLFLPBHK_02468 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
CLFLPBHK_02469 4.66e-186 ywpD - - T - - - Histidine kinase
CLFLPBHK_02470 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CLFLPBHK_02471 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CLFLPBHK_02472 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
CLFLPBHK_02473 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CLFLPBHK_02474 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CLFLPBHK_02475 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
CLFLPBHK_02476 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
CLFLPBHK_02477 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
CLFLPBHK_02478 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02479 3.25e-309 ywoF - - P - - - Right handed beta helix region
CLFLPBHK_02480 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
CLFLPBHK_02481 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
CLFLPBHK_02482 1.04e-133 yjgF - - Q - - - Isochorismatase family
CLFLPBHK_02483 7.16e-101 - - - - - - - -
CLFLPBHK_02484 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
CLFLPBHK_02485 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
CLFLPBHK_02486 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
CLFLPBHK_02487 9.05e-93 ywnJ - - S - - - VanZ like family
CLFLPBHK_02488 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CLFLPBHK_02489 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
CLFLPBHK_02490 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
CLFLPBHK_02491 6.7e-234 - - - M - - - NeuB family
CLFLPBHK_02492 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
CLFLPBHK_02493 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CLFLPBHK_02494 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
CLFLPBHK_02495 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
CLFLPBHK_02496 1.42e-112 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
CLFLPBHK_02497 6.73e-19 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
CLFLPBHK_02498 4.58e-85 ywnA - - K - - - Transcriptional regulator
CLFLPBHK_02499 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CLFLPBHK_02500 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
CLFLPBHK_02501 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
CLFLPBHK_02502 0.000282 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
CLFLPBHK_02503 2.15e-19 csbD - - K - - - CsbD-like
CLFLPBHK_02504 8.55e-110 ywmF - - S - - - Peptidase M50
CLFLPBHK_02505 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_02506 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CLFLPBHK_02507 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CLFLPBHK_02509 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CLFLPBHK_02510 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CLFLPBHK_02511 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
CLFLPBHK_02512 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLFLPBHK_02513 6.59e-172 ywmB - - S - - - TATA-box binding
CLFLPBHK_02514 4.54e-45 ywzB - - S - - - membrane
CLFLPBHK_02515 2.92e-113 ywmA - - - - - - -
CLFLPBHK_02516 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CLFLPBHK_02517 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CLFLPBHK_02518 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CLFLPBHK_02519 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CLFLPBHK_02520 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLFLPBHK_02521 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CLFLPBHK_02522 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CLFLPBHK_02523 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CLFLPBHK_02524 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
CLFLPBHK_02525 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CLFLPBHK_02526 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CLFLPBHK_02527 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
CLFLPBHK_02528 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
CLFLPBHK_02529 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLFLPBHK_02530 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
CLFLPBHK_02531 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CLFLPBHK_02532 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
CLFLPBHK_02533 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
CLFLPBHK_02534 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CLFLPBHK_02536 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CLFLPBHK_02537 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CLFLPBHK_02538 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_02539 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CLFLPBHK_02540 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
CLFLPBHK_02541 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CLFLPBHK_02542 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CLFLPBHK_02543 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
CLFLPBHK_02544 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CLFLPBHK_02545 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
CLFLPBHK_02546 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CLFLPBHK_02548 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CLFLPBHK_02549 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
CLFLPBHK_02550 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
CLFLPBHK_02551 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
CLFLPBHK_02552 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLFLPBHK_02553 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CLFLPBHK_02554 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
CLFLPBHK_02555 1.36e-123 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
CLFLPBHK_02556 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CLFLPBHK_02558 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
CLFLPBHK_02559 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CLFLPBHK_02560 1.97e-46 yuiB - - S - - - Putative membrane protein
CLFLPBHK_02561 2.69e-148 yuiC - - S - - - protein conserved in bacteria
CLFLPBHK_02562 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
CLFLPBHK_02563 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CLFLPBHK_02564 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
CLFLPBHK_02565 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
CLFLPBHK_02566 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
CLFLPBHK_02567 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
CLFLPBHK_02568 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02569 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CLFLPBHK_02570 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
CLFLPBHK_02571 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
CLFLPBHK_02572 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_02573 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
CLFLPBHK_02574 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
CLFLPBHK_02575 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
CLFLPBHK_02576 2.96e-292 yukF - - QT - - - Transcriptional regulator
CLFLPBHK_02577 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
CLFLPBHK_02578 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
CLFLPBHK_02579 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
CLFLPBHK_02580 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CLFLPBHK_02581 0.0 yueB - - S - - - type VII secretion protein EsaA
CLFLPBHK_02582 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
CLFLPBHK_02583 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_02584 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
CLFLPBHK_02585 1.19e-32 - - - S - - - Protein of unknown function (DUF2642)
CLFLPBHK_02586 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
CLFLPBHK_02587 1.35e-244 yueF - - S - - - transporter activity
CLFLPBHK_02588 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
CLFLPBHK_02589 1.63e-52 yueH - - S - - - YueH-like protein
CLFLPBHK_02590 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
CLFLPBHK_02591 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
CLFLPBHK_02592 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CLFLPBHK_02593 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
CLFLPBHK_02594 8.73e-09 yuzC - - - - - - -
CLFLPBHK_02596 6.29e-10 - - - S - - - DegQ (SacQ) family
CLFLPBHK_02597 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
CLFLPBHK_02599 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CLFLPBHK_02600 2.46e-67 - - - - - - - -
CLFLPBHK_02601 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
CLFLPBHK_02602 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
CLFLPBHK_02603 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CLFLPBHK_02604 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
CLFLPBHK_02605 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLFLPBHK_02606 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CLFLPBHK_02607 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CLFLPBHK_02608 6.92e-92 yviE - - - - - - -
CLFLPBHK_02609 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
CLFLPBHK_02610 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
CLFLPBHK_02611 7.06e-102 yvyG - - NOU - - - FlgN protein
CLFLPBHK_02612 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
CLFLPBHK_02613 1.06e-95 yvyF - - S - - - flagellar protein
CLFLPBHK_02614 1.66e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
CLFLPBHK_02615 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
CLFLPBHK_02616 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CLFLPBHK_02617 1.24e-198 degV - - S - - - protein conserved in bacteria
CLFLPBHK_02618 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_02619 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CLFLPBHK_02620 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
CLFLPBHK_02621 1.23e-151 - - - K - - - Transcriptional regulator
CLFLPBHK_02625 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
CLFLPBHK_02628 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_02630 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CLFLPBHK_02631 7.15e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
CLFLPBHK_02632 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CLFLPBHK_02633 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
CLFLPBHK_02634 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
CLFLPBHK_02636 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CLFLPBHK_02637 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
CLFLPBHK_02638 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_02639 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CLFLPBHK_02640 8.96e-11 - - - S - - - Protein of unknown function (DUF3918)
CLFLPBHK_02641 8.4e-42 yrzR - - - - - - -
CLFLPBHK_02642 2.79e-105 yrrD - - S - - - protein conserved in bacteria
CLFLPBHK_02643 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CLFLPBHK_02644 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
CLFLPBHK_02645 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CLFLPBHK_02646 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CLFLPBHK_02647 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_02648 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CLFLPBHK_02649 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CLFLPBHK_02650 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CLFLPBHK_02651 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CLFLPBHK_02653 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
CLFLPBHK_02654 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CLFLPBHK_02655 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CLFLPBHK_02656 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CLFLPBHK_02657 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CLFLPBHK_02658 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
CLFLPBHK_02659 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CLFLPBHK_02660 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CLFLPBHK_02661 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
CLFLPBHK_02662 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CLFLPBHK_02663 8.64e-145 yrbG - - S - - - membrane
CLFLPBHK_02664 2.16e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
CLFLPBHK_02665 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
CLFLPBHK_02666 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CLFLPBHK_02667 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CLFLPBHK_02668 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
CLFLPBHK_02669 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CLFLPBHK_02670 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CLFLPBHK_02671 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
CLFLPBHK_02672 0.0 csbX - - EGP - - - the major facilitator superfamily
CLFLPBHK_02673 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
CLFLPBHK_02674 1.91e-151 yrzF - - T - - - serine threonine protein kinase
CLFLPBHK_02676 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
CLFLPBHK_02677 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
CLFLPBHK_02678 3.51e-164 yebC - - K - - - transcriptional regulatory protein
CLFLPBHK_02679 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CLFLPBHK_02680 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
CLFLPBHK_02681 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CLFLPBHK_02682 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
CLFLPBHK_02683 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
CLFLPBHK_02684 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CLFLPBHK_02685 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
CLFLPBHK_02686 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
CLFLPBHK_02687 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
CLFLPBHK_02688 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CLFLPBHK_02689 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
CLFLPBHK_02690 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CLFLPBHK_02691 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
CLFLPBHK_02692 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CLFLPBHK_02693 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
CLFLPBHK_02694 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CLFLPBHK_02695 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
CLFLPBHK_02696 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CLFLPBHK_02697 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
CLFLPBHK_02698 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CLFLPBHK_02699 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
CLFLPBHK_02700 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
CLFLPBHK_02701 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
CLFLPBHK_02702 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
CLFLPBHK_02703 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CLFLPBHK_02704 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CLFLPBHK_02705 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CLFLPBHK_02706 1.53e-35 - - - - - - - -
CLFLPBHK_02707 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CLFLPBHK_02708 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
CLFLPBHK_02709 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CLFLPBHK_02710 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
CLFLPBHK_02711 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CLFLPBHK_02712 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CLFLPBHK_02713 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
CLFLPBHK_02714 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CLFLPBHK_02715 4.77e-116 ysxD - - - - - - -
CLFLPBHK_02716 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CLFLPBHK_02717 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CLFLPBHK_02718 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
CLFLPBHK_02719 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CLFLPBHK_02720 5.98e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CLFLPBHK_02721 2.62e-238 ysoA - - H - - - Tetratricopeptide repeat
CLFLPBHK_02722 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLFLPBHK_02723 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CLFLPBHK_02724 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CLFLPBHK_02725 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CLFLPBHK_02726 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CLFLPBHK_02727 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CLFLPBHK_02728 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CLFLPBHK_02730 3.28e-46 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
CLFLPBHK_02731 3.36e-181 ysnF - - S - - - protein conserved in bacteria
CLFLPBHK_02732 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CLFLPBHK_02734 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CLFLPBHK_02735 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
CLFLPBHK_02736 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
CLFLPBHK_02737 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CLFLPBHK_02739 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
CLFLPBHK_02740 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
CLFLPBHK_02741 1.13e-29 yjfB - - S - - - Putative motility protein
CLFLPBHK_02742 1.93e-62 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
CLFLPBHK_02743 3.15e-136 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
CLFLPBHK_02744 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
CLFLPBHK_02745 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
CLFLPBHK_02746 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
CLFLPBHK_02747 5.25e-113 yjgD - - S - - - Protein of unknown function (DUF1641)
CLFLPBHK_02749 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CLFLPBHK_02751 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CLFLPBHK_02752 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CLFLPBHK_02753 1.11e-41 - - - - - - - -
CLFLPBHK_02754 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CLFLPBHK_02755 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLFLPBHK_02756 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_02757 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_02758 3.06e-204 yuxN - - K - - - Transcriptional regulator
CLFLPBHK_02759 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CLFLPBHK_02760 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
CLFLPBHK_02761 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CLFLPBHK_02762 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CLFLPBHK_02763 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
CLFLPBHK_02764 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_02765 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_02766 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
CLFLPBHK_02767 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CLFLPBHK_02768 2.85e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CLFLPBHK_02769 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
CLFLPBHK_02770 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02771 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
CLFLPBHK_02772 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CLFLPBHK_02773 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_02774 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CLFLPBHK_02775 2.89e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02776 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
CLFLPBHK_02777 0.0 yvrG - - T - - - Histidine kinase
CLFLPBHK_02778 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_02779 5.07e-32 - - - - - - - -
CLFLPBHK_02780 1.12e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
CLFLPBHK_02781 3.46e-26 - - - S - - - YvrJ protein family
CLFLPBHK_02782 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CLFLPBHK_02783 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
CLFLPBHK_02784 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CLFLPBHK_02785 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_02786 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
CLFLPBHK_02787 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CLFLPBHK_02788 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_02789 4.04e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_02790 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CLFLPBHK_02792 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
CLFLPBHK_02793 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
CLFLPBHK_02794 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
CLFLPBHK_02795 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
CLFLPBHK_02796 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
CLFLPBHK_02797 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
CLFLPBHK_02798 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
CLFLPBHK_02799 6.19e-201 yvgN - - S - - - reductase
CLFLPBHK_02800 9.32e-112 yvgO - - - - - - -
CLFLPBHK_02801 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
CLFLPBHK_02802 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CLFLPBHK_02803 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CLFLPBHK_02804 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CLFLPBHK_02806 6.7e-139 yvgT - - S - - - membrane
CLFLPBHK_02807 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
CLFLPBHK_02808 3.45e-137 bdbD - - O - - - Thioredoxin
CLFLPBHK_02809 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CLFLPBHK_02810 6.83e-45 - - - - - - - -
CLFLPBHK_02811 0.0 - - - V - - - Abi-like protein
CLFLPBHK_02812 0.0 - - - L - - - Superfamily I DNA and RNA helicases
CLFLPBHK_02813 0.0 - - - L - - - AAA ATPase domain
CLFLPBHK_02814 6.23e-148 - - - S - - - HTH-like domain
CLFLPBHK_02815 1.07e-57 - - - S - - - transposition, DNA-mediated
CLFLPBHK_02817 3.99e-53 - - - - - - - -
CLFLPBHK_02818 3.17e-176 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
CLFLPBHK_02819 1.59e-65 - - - L - - - Transposase
CLFLPBHK_02820 5.47e-135 - - - L - - - helicase superfamily c-terminal domain
CLFLPBHK_02822 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CLFLPBHK_02824 1.64e-89 - - - - - - - -
CLFLPBHK_02825 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CLFLPBHK_02827 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
CLFLPBHK_02828 2.71e-260 yycP - - - - - - -
CLFLPBHK_02829 3.06e-156 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CLFLPBHK_02830 4.15e-108 yycN - - K - - - Acetyltransferase
CLFLPBHK_02831 1.17e-18 - - - S - - - aspartate phosphatase
CLFLPBHK_02832 2.06e-204 - - - S - - - aspartate phosphatase
CLFLPBHK_02834 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CLFLPBHK_02835 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CLFLPBHK_02836 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
CLFLPBHK_02837 5.82e-20 - - - - - - - -
CLFLPBHK_02838 4.85e-119 - - - - - - - -
CLFLPBHK_02839 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
CLFLPBHK_02840 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
CLFLPBHK_02841 2.31e-54 sdpR - - K - - - transcriptional
CLFLPBHK_02842 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CLFLPBHK_02843 2.32e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLFLPBHK_02844 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CLFLPBHK_02845 3.44e-200 yycI - - S - - - protein conserved in bacteria
CLFLPBHK_02846 0.0 yycH - - S - - - protein conserved in bacteria
CLFLPBHK_02847 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_02848 2.07e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_02853 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CLFLPBHK_02854 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_02855 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CLFLPBHK_02856 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
CLFLPBHK_02858 1.89e-22 yycC - - K - - - YycC-like protein
CLFLPBHK_02859 2.22e-278 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
CLFLPBHK_02860 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CLFLPBHK_02861 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CLFLPBHK_02862 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CLFLPBHK_02863 1.14e-34 yybS - - S - - - membrane
CLFLPBHK_02864 4.15e-120 yybS - - S - - - membrane
CLFLPBHK_02866 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
CLFLPBHK_02867 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
CLFLPBHK_02868 1.3e-87 yybR - - K - - - Transcriptional regulator
CLFLPBHK_02869 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
CLFLPBHK_02870 3.19e-90 - - - - - - - -
CLFLPBHK_02872 5.21e-70 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02873 7.94e-200 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02874 7.24e-141 - - - K - - - TipAS antibiotic-recognition domain
CLFLPBHK_02875 2.05e-183 - - - - - - - -
CLFLPBHK_02876 5.02e-87 - - - S - - - SnoaL-like domain
CLFLPBHK_02877 6.02e-157 yybG - - S - - - Pentapeptide repeat-containing protein
CLFLPBHK_02878 3.87e-132 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_02879 4.41e-105 - - - S - - - Metallo-beta-lactamase superfamily
CLFLPBHK_02880 4.54e-100 yybA - - K - - - transcriptional
CLFLPBHK_02881 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
CLFLPBHK_02882 1.55e-125 yyaS - - S ko:K07149 - ko00000 Membrane
CLFLPBHK_02883 3.81e-87 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
CLFLPBHK_02884 2.28e-48 - - - S - - - YjbR
CLFLPBHK_02885 1.67e-134 yyaP - - H - - - RibD C-terminal domain
CLFLPBHK_02886 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
CLFLPBHK_02887 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
CLFLPBHK_02888 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
CLFLPBHK_02889 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
CLFLPBHK_02890 3.01e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
CLFLPBHK_02891 4.69e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_02892 2.14e-154 ccpB - - K - - - Transcriptional regulator
CLFLPBHK_02893 2.65e-60 ccpB - - K - - - Transcriptional regulator
CLFLPBHK_02894 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CLFLPBHK_02895 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CLFLPBHK_02896 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CLFLPBHK_02897 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CLFLPBHK_02898 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CLFLPBHK_02899 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CLFLPBHK_02900 7.41e-45 yyzM - - S - - - protein conserved in bacteria
CLFLPBHK_02901 5.34e-227 yyaD - - S - - - Membrane
CLFLPBHK_02902 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
CLFLPBHK_02903 7.65e-83 yhfM - - - - - - -
CLFLPBHK_02904 9.64e-308 yhfN - - O - - - Peptidase M48
CLFLPBHK_02905 5.67e-259 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CLFLPBHK_02906 5.98e-100 - - - K - - - acetyltransferase
CLFLPBHK_02907 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
CLFLPBHK_02908 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
CLFLPBHK_02909 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
CLFLPBHK_02910 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CLFLPBHK_02911 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CLFLPBHK_02912 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
CLFLPBHK_02913 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
CLFLPBHK_02914 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
CLFLPBHK_02915 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
CLFLPBHK_02916 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
CLFLPBHK_02917 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_02918 9.84e-45 yhzC - - S - - - IDEAL
CLFLPBHK_02919 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
CLFLPBHK_02920 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CLFLPBHK_02921 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
CLFLPBHK_02922 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CLFLPBHK_02923 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
CLFLPBHK_02924 4.13e-78 yhjD - - - - - - -
CLFLPBHK_02925 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
CLFLPBHK_02926 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CLFLPBHK_02927 0.0 yhjG - - CH - - - FAD binding domain
CLFLPBHK_02928 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
CLFLPBHK_02931 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
CLFLPBHK_02932 9.38e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
CLFLPBHK_02933 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
CLFLPBHK_02934 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
CLFLPBHK_02935 5.09e-238 yhjM - - K - - - Transcriptional regulator
CLFLPBHK_02936 5.04e-259 yhjN - - S ko:K07120 - ko00000 membrane
CLFLPBHK_02937 1.36e-267 - - - EGP - - - Transmembrane secretion effector
CLFLPBHK_02938 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
CLFLPBHK_02939 6.29e-100 yhjR - - S - - - Rubrerythrin
CLFLPBHK_02940 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
CLFLPBHK_02941 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CLFLPBHK_02942 3.84e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CLFLPBHK_02943 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
CLFLPBHK_02944 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
CLFLPBHK_02945 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
CLFLPBHK_02946 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
CLFLPBHK_02947 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
CLFLPBHK_02948 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
CLFLPBHK_02949 1.02e-46 gerPB - - S ko:K06300 - ko00000 cell differentiation
CLFLPBHK_02950 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
CLFLPBHK_02951 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
CLFLPBHK_02952 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
CLFLPBHK_02953 3.11e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CLFLPBHK_02954 1.02e-74 yisL - - S - - - UPF0344 protein
CLFLPBHK_02955 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CLFLPBHK_02956 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CLFLPBHK_02957 3.75e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLFLPBHK_02958 1.81e-41 yazB - - K - - - transcriptional
CLFLPBHK_02959 1.31e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CLFLPBHK_02960 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CLFLPBHK_02961 5.28e-202 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CLFLPBHK_02962 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
CLFLPBHK_02963 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
CLFLPBHK_02964 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CLFLPBHK_02966 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CLFLPBHK_02967 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CLFLPBHK_02968 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
CLFLPBHK_02969 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_02970 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
CLFLPBHK_02972 0.0 - - - O - - - Peptidase family M48
CLFLPBHK_02973 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
CLFLPBHK_02974 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CLFLPBHK_02975 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
CLFLPBHK_02976 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
CLFLPBHK_02977 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
CLFLPBHK_02978 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CLFLPBHK_02979 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
CLFLPBHK_02980 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_02981 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
CLFLPBHK_02982 1.63e-39 - - - - - - - -
CLFLPBHK_02983 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
CLFLPBHK_02984 3.33e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_02985 1.14e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CLFLPBHK_02986 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
CLFLPBHK_02987 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CLFLPBHK_02988 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
CLFLPBHK_02989 1.05e-26 yxzF - - - - - - -
CLFLPBHK_02990 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
CLFLPBHK_02991 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
CLFLPBHK_02992 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CLFLPBHK_02993 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_02994 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CLFLPBHK_02995 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CLFLPBHK_02996 3.56e-43 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02997 2.19e-07 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02998 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_02999 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CLFLPBHK_03000 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_03001 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
CLFLPBHK_03002 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_03004 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
CLFLPBHK_03005 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLFLPBHK_03006 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CLFLPBHK_03007 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_03008 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
CLFLPBHK_03009 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CLFLPBHK_03010 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_03012 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
CLFLPBHK_03014 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLFLPBHK_03015 1.87e-65 yqiX - - S - - - YolD-like protein
CLFLPBHK_03016 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
CLFLPBHK_03017 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
CLFLPBHK_03018 3.23e-248 yqkA - - K - - - GrpB protein
CLFLPBHK_03019 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
CLFLPBHK_03020 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
CLFLPBHK_03021 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CLFLPBHK_03022 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
CLFLPBHK_03023 2.09e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
CLFLPBHK_03024 6.19e-09 - - - S - - - Protein of unknown function (DUF3936)
CLFLPBHK_03025 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
CLFLPBHK_03026 1.45e-280 yqxK - - L - - - DNA helicase
CLFLPBHK_03027 3.18e-77 ansR - - K - - - Transcriptional regulator
CLFLPBHK_03028 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
CLFLPBHK_03029 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
CLFLPBHK_03030 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CLFLPBHK_03031 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CLFLPBHK_03032 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CLFLPBHK_03033 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
CLFLPBHK_03034 9.89e-201 yugF - - I - - - Hydrolase
CLFLPBHK_03035 6.74e-112 alaR - - K - - - Transcriptional regulator
CLFLPBHK_03036 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
CLFLPBHK_03037 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CLFLPBHK_03038 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
CLFLPBHK_03039 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
CLFLPBHK_03040 1.2e-285 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
CLFLPBHK_03041 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CLFLPBHK_03043 2.75e-91 yugN - - S - - - YugN-like family
CLFLPBHK_03044 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
CLFLPBHK_03045 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
CLFLPBHK_03046 2.16e-48 - - - - - - - -
CLFLPBHK_03047 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
CLFLPBHK_03048 7.23e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CLFLPBHK_03049 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CLFLPBHK_03050 5e-48 - - - - - - - -
CLFLPBHK_03051 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
CLFLPBHK_03052 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_03053 2.02e-284 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_03054 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_03055 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_03056 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CLFLPBHK_03057 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
CLFLPBHK_03058 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CLFLPBHK_03059 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CLFLPBHK_03060 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
CLFLPBHK_03061 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
CLFLPBHK_03062 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CLFLPBHK_03063 1.73e-252 yubA - - S - - - transporter activity
CLFLPBHK_03064 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CLFLPBHK_03066 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
CLFLPBHK_03067 0.0 yubD - - P - - - Major Facilitator Superfamily
CLFLPBHK_03068 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CLFLPBHK_03069 3.31e-52 yubF - - S - - - yiaA/B two helix domain
CLFLPBHK_03070 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
CLFLPBHK_03071 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CLFLPBHK_03072 5.83e-118 yuaB - - - - - - -
CLFLPBHK_03073 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
CLFLPBHK_03074 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CLFLPBHK_03075 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
CLFLPBHK_03076 1.12e-134 yuaD - - - - - - -
CLFLPBHK_03077 9.58e-67 - - - M - - - ArpU family transcriptional regulator
CLFLPBHK_03078 1.6e-94 - - - L - - - Phage integrase family
CLFLPBHK_03079 3.2e-265 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CLFLPBHK_03080 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
CLFLPBHK_03081 6.01e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
CLFLPBHK_03082 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_03083 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
CLFLPBHK_03084 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CLFLPBHK_03085 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CLFLPBHK_03086 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
CLFLPBHK_03087 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CLFLPBHK_03088 4.54e-205 ytbE - - S - - - reductase
CLFLPBHK_03089 1.6e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
CLFLPBHK_03090 1.15e-86 ytcD - - K - - - Transcriptional regulator
CLFLPBHK_03091 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CLFLPBHK_03092 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CLFLPBHK_03093 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CLFLPBHK_03094 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
CLFLPBHK_03095 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CLFLPBHK_03096 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
CLFLPBHK_03097 2e-204 ytxC - - S - - - YtxC-like family
CLFLPBHK_03099 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLFLPBHK_03100 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
CLFLPBHK_03101 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_03102 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
CLFLPBHK_03103 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CLFLPBHK_03104 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CLFLPBHK_03106 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CLFLPBHK_03107 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CLFLPBHK_03108 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CLFLPBHK_03109 3.65e-59 ysdA - - S - - - Membrane
CLFLPBHK_03110 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
CLFLPBHK_03111 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
CLFLPBHK_03112 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CLFLPBHK_03113 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
CLFLPBHK_03114 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
CLFLPBHK_03115 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CLFLPBHK_03116 1.46e-87 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
CLFLPBHK_03117 2.52e-61 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
CLFLPBHK_03118 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CLFLPBHK_03119 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
CLFLPBHK_03120 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
CLFLPBHK_03121 1.01e-188 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
CLFLPBHK_03122 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
CLFLPBHK_03123 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
CLFLPBHK_03124 8.42e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
CLFLPBHK_03125 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
CLFLPBHK_03126 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
CLFLPBHK_03127 3.19e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
CLFLPBHK_03128 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
CLFLPBHK_03129 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CLFLPBHK_03130 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CLFLPBHK_03131 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CLFLPBHK_03132 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CLFLPBHK_03133 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CLFLPBHK_03134 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
CLFLPBHK_03135 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
CLFLPBHK_03136 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CLFLPBHK_03137 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
CLFLPBHK_03138 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CLFLPBHK_03139 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03140 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
CLFLPBHK_03141 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
CLFLPBHK_03142 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
CLFLPBHK_03144 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
CLFLPBHK_03145 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CLFLPBHK_03146 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CLFLPBHK_03147 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CLFLPBHK_03148 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
CLFLPBHK_03149 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
CLFLPBHK_03150 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CLFLPBHK_03151 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CLFLPBHK_03152 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
CLFLPBHK_03153 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03154 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
CLFLPBHK_03155 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CLFLPBHK_03156 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
CLFLPBHK_03157 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CLFLPBHK_03158 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CLFLPBHK_03159 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
CLFLPBHK_03161 3.17e-170 - - - L - - - Phage integrase family
CLFLPBHK_03164 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CLFLPBHK_03165 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
CLFLPBHK_03166 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
CLFLPBHK_03167 3.84e-87 res - - L - - - Resolvase, N terminal domain
CLFLPBHK_03169 1.45e-38 - - - - - - - -
CLFLPBHK_03172 1.73e-70 - - - K - - - Helix-turn-helix
CLFLPBHK_03173 2.11e-49 - - - S - - - TM2 domain
CLFLPBHK_03174 2.62e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
CLFLPBHK_03175 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
CLFLPBHK_03178 8.51e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
CLFLPBHK_03179 4.88e-147 lin0465 - - S - - - DJ-1/PfpI family
CLFLPBHK_03180 1.89e-100 yoaW - - - - - - -
CLFLPBHK_03181 3.7e-201 yoaV - - EG - - - EamA-like transporter family
CLFLPBHK_03182 1.35e-202 yoaU - - K - - - LysR substrate binding domain
CLFLPBHK_03183 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
CLFLPBHK_03184 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03185 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
CLFLPBHK_03186 5.78e-215 yoaR - - V - - - vancomycin resistance protein
CLFLPBHK_03187 2.01e-108 - - - - - - - -
CLFLPBHK_03190 3.1e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CLFLPBHK_03192 2.28e-67 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
CLFLPBHK_03193 2.87e-119 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
CLFLPBHK_03194 1.79e-66 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
CLFLPBHK_03195 1.79e-145 yoaK - - S - - - Membrane
CLFLPBHK_03196 3.56e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
CLFLPBHK_03197 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
CLFLPBHK_03198 1.88e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
CLFLPBHK_03199 5.32e-60 - - - L - - - Transposase and inactivated derivatives, TnpA family
CLFLPBHK_03200 2.2e-100 - - - - - - - -
CLFLPBHK_03201 5.09e-42 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_03202 5.92e-194 - - - EG - - - Spore germination protein
CLFLPBHK_03203 2.28e-13 - - - S - - - TIGRFAM germination protein, Ger(x)C family
CLFLPBHK_03204 2.56e-34 - - - S - - - Protein of unknown function (DUF2642)
CLFLPBHK_03205 7.51e-205 - - - P - - - Catalase
CLFLPBHK_03206 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
CLFLPBHK_03207 5.84e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
CLFLPBHK_03208 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
CLFLPBHK_03209 4.34e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
CLFLPBHK_03210 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
CLFLPBHK_03211 9.73e-194 - - - S - - - membrane
CLFLPBHK_03212 1.38e-16 - - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_03213 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_03214 0.0 - - - I - - - PLD-like domain
CLFLPBHK_03215 7.71e-128 - - - S - - - Protein of unknown function (DUF421)
CLFLPBHK_03216 2.23e-112 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
CLFLPBHK_03217 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
CLFLPBHK_03218 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CLFLPBHK_03219 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
CLFLPBHK_03220 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_03221 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_03222 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CLFLPBHK_03223 7.05e-172 yoxB - - - - - - -
CLFLPBHK_03224 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
CLFLPBHK_03225 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_03226 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CLFLPBHK_03227 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLFLPBHK_03228 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CLFLPBHK_03229 2.05e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CLFLPBHK_03230 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03231 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
CLFLPBHK_03232 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CLFLPBHK_03233 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CLFLPBHK_03234 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03235 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CLFLPBHK_03236 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
CLFLPBHK_03237 1.14e-124 - - - L - - - Integrase
CLFLPBHK_03239 8.34e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
CLFLPBHK_03240 1.14e-311 yoeA - - V - - - MATE efflux family protein
CLFLPBHK_03241 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CLFLPBHK_03242 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CLFLPBHK_03243 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_03244 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
CLFLPBHK_03245 7.8e-49 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
CLFLPBHK_03246 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
CLFLPBHK_03247 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
CLFLPBHK_03248 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CLFLPBHK_03249 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CLFLPBHK_03250 5.62e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
CLFLPBHK_03251 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
CLFLPBHK_03252 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
CLFLPBHK_03253 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
CLFLPBHK_03254 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CLFLPBHK_03255 1.74e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
CLFLPBHK_03256 1.16e-133 yngC - - S - - - membrane-associated protein
CLFLPBHK_03257 1.07e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CLFLPBHK_03258 1.36e-100 yngA - - S - - - membrane
CLFLPBHK_03259 8.44e-31 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CLFLPBHK_03260 5.7e-309 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CLFLPBHK_03261 2.36e-315 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
CLFLPBHK_03263 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
CLFLPBHK_03264 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CLFLPBHK_03265 8.74e-75 ynfC - - - - - - -
CLFLPBHK_03266 1.82e-18 - - - - - - - -
CLFLPBHK_03267 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLFLPBHK_03268 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CLFLPBHK_03269 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
CLFLPBHK_03270 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CLFLPBHK_03271 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
CLFLPBHK_03272 3.3e-71 yneQ - - - - - - -
CLFLPBHK_03273 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
CLFLPBHK_03274 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
CLFLPBHK_03276 9.26e-10 - - - S - - - Fur-regulated basic protein B
CLFLPBHK_03277 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CLFLPBHK_03278 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CLFLPBHK_03279 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
CLFLPBHK_03280 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
CLFLPBHK_03281 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
CLFLPBHK_03282 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
CLFLPBHK_03283 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CLFLPBHK_03285 5.36e-203 ybaS - - S - - - Na -dependent transporter
CLFLPBHK_03286 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
CLFLPBHK_03287 1.43e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03288 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03289 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
CLFLPBHK_03290 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
CLFLPBHK_03291 6.63e-270 ybbC - - S - - - protein conserved in bacteria
CLFLPBHK_03292 8.03e-21 ybbC - - S - - - protein conserved in bacteria
CLFLPBHK_03293 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
CLFLPBHK_03294 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
CLFLPBHK_03295 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_03296 3.14e-193 ybbH - - K - - - transcriptional
CLFLPBHK_03297 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CLFLPBHK_03298 8.99e-114 ybbJ - - J - - - acetyltransferase
CLFLPBHK_03299 9.88e-100 ybbK - - S - - - Protein of unknown function (DUF523)
CLFLPBHK_03305 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_03306 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CLFLPBHK_03307 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CLFLPBHK_03308 3.55e-291 ybbR - - S - - - protein conserved in bacteria
CLFLPBHK_03309 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CLFLPBHK_03310 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CLFLPBHK_03314 1.12e-07 - - - S - - - YopX protein
CLFLPBHK_03316 1.76e-59 - - - S - - - dUTPase
CLFLPBHK_03322 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_03323 4.65e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
CLFLPBHK_03324 1.49e-192 ybdN - - - - - - -
CLFLPBHK_03325 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
CLFLPBHK_03327 2.05e-131 - - - T - - - His Kinase A (phospho-acceptor) domain
CLFLPBHK_03328 1.89e-70 - - - T - - - His Kinase A (phospho-acceptor) domain
CLFLPBHK_03329 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
CLFLPBHK_03330 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
CLFLPBHK_03331 5.59e-64 - - - - - - - -
CLFLPBHK_03332 1.34e-120 ybcF - - P - - - carbonic anhydrase
CLFLPBHK_03333 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
CLFLPBHK_03334 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CLFLPBHK_03335 8.33e-58 - - - S - - - Metallo-beta-lactamase superfamily
CLFLPBHK_03336 1.42e-56 - - - S - - - MepB protein
CLFLPBHK_03337 0.0 - - - IQ ko:K15641,ko:K16398,ko:K16417,ko:K20788 ko01052,map01052 ko00000,ko00001,ko01008 PKS_KR
CLFLPBHK_03338 3.09e-63 - - - S - - - dUTPase
CLFLPBHK_03344 8.04e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLFLPBHK_03345 3.25e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
CLFLPBHK_03346 8.23e-112 yteJ - - S - - - RDD family
CLFLPBHK_03347 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
CLFLPBHK_03348 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
CLFLPBHK_03349 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CLFLPBHK_03350 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
CLFLPBHK_03352 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CLFLPBHK_03353 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
CLFLPBHK_03354 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
CLFLPBHK_03355 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
CLFLPBHK_03357 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_03358 4.53e-166 ytkL - - S - - - Belongs to the UPF0173 family
CLFLPBHK_03359 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
CLFLPBHK_03360 2.15e-63 ytpI - - S - - - YtpI-like protein
CLFLPBHK_03361 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
CLFLPBHK_03362 1.15e-39 - - - - - - - -
CLFLPBHK_03363 5.12e-112 ytrI - - - - - - -
CLFLPBHK_03364 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
CLFLPBHK_03365 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CLFLPBHK_03366 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CLFLPBHK_03367 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CLFLPBHK_03368 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CLFLPBHK_03369 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CLFLPBHK_03370 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CLFLPBHK_03371 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
CLFLPBHK_03372 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
CLFLPBHK_03373 9.38e-95 ytwI - - S - - - membrane
CLFLPBHK_03374 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
CLFLPBHK_03375 5.46e-74 ygzB - - S - - - UPF0295 protein
CLFLPBHK_03376 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
CLFLPBHK_03377 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
CLFLPBHK_03378 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CLFLPBHK_03379 8.86e-237 ygaE - - S - - - Membrane
CLFLPBHK_03380 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
CLFLPBHK_03381 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
CLFLPBHK_03382 2.01e-49 ygaB - - S - - - YgaB-like protein
CLFLPBHK_03383 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
CLFLPBHK_03384 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_03385 1.73e-48 yfhS - - - - - - -
CLFLPBHK_03386 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
CLFLPBHK_03387 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
CLFLPBHK_03388 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
CLFLPBHK_03389 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CLFLPBHK_03390 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
CLFLPBHK_03391 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
CLFLPBHK_03392 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
CLFLPBHK_03393 8.95e-60 yfhJ - - S - - - WVELL protein
CLFLPBHK_03394 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
CLFLPBHK_03395 2.45e-268 yfhI - - EGP - - - -transporter
CLFLPBHK_03397 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
CLFLPBHK_03398 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
CLFLPBHK_03399 2.56e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
CLFLPBHK_03401 8.86e-35 yfhD - - S - - - YfhD-like protein
CLFLPBHK_03402 1.17e-137 yfhC - - C - - - nitroreductase
CLFLPBHK_03403 9.95e-211 yfhB - - S - - - PhzF family
CLFLPBHK_03404 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03405 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03406 1.28e-229 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CLFLPBHK_03407 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CLFLPBHK_03408 4.26e-103 yfiV - - K - - - transcriptional
CLFLPBHK_03409 7.8e-22 yfiU - - EGP - - - the major facilitator superfamily
CLFLPBHK_03410 1.11e-291 yfiU - - EGP - - - the major facilitator superfamily
CLFLPBHK_03411 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
CLFLPBHK_03412 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
CLFLPBHK_03413 4.01e-139 yfiR - - K - - - Transcriptional regulator
CLFLPBHK_03414 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CLFLPBHK_03415 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
CLFLPBHK_03416 1.89e-128 padR - - K - - - transcriptional
CLFLPBHK_03417 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
CLFLPBHK_03418 5.69e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
CLFLPBHK_03419 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_03420 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
CLFLPBHK_03421 1.7e-272 baeS - - T - - - Histidine kinase
CLFLPBHK_03423 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
CLFLPBHK_03424 1.93e-82 yfiD3 - - S - - - DoxX
CLFLPBHK_03425 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CLFLPBHK_03426 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
CLFLPBHK_03427 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_03428 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
CLFLPBHK_03429 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CLFLPBHK_03430 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
CLFLPBHK_03431 1.94e-270 yfjB - - - - - - -
CLFLPBHK_03432 1.02e-184 yfjC - - - - - - -
CLFLPBHK_03433 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
CLFLPBHK_03434 1e-105 - - - S - - - Family of unknown function (DUF5381)
CLFLPBHK_03435 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
CLFLPBHK_03436 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
CLFLPBHK_03437 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
CLFLPBHK_03438 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CLFLPBHK_03439 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLFLPBHK_03440 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CLFLPBHK_03441 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CLFLPBHK_03443 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
CLFLPBHK_03444 1.25e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CLFLPBHK_03445 3.04e-59 - - - S - - - YfzA-like protein
CLFLPBHK_03446 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLFLPBHK_03447 3.92e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CLFLPBHK_03448 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
CLFLPBHK_03449 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CLFLPBHK_03450 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
CLFLPBHK_03451 3.26e-36 yfjT - - - - - - -
CLFLPBHK_03452 1.76e-283 yfkA - - S - - - YfkB-like domain
CLFLPBHK_03453 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
CLFLPBHK_03454 3.69e-189 yfkD - - S - - - YfkD-like protein
CLFLPBHK_03455 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
CLFLPBHK_03456 7.74e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_03457 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CLFLPBHK_03458 1.03e-66 yfkI - - S - - - gas vesicle protein
CLFLPBHK_03459 5.89e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CLFLPBHK_03460 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
CLFLPBHK_03461 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_03462 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CLFLPBHK_03463 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CLFLPBHK_03464 6.16e-160 frp - - C - - - nitroreductase
CLFLPBHK_03465 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
CLFLPBHK_03466 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
CLFLPBHK_03467 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_03468 1.43e-41 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
CLFLPBHK_03469 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
CLFLPBHK_03470 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CLFLPBHK_03471 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CLFLPBHK_03472 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CLFLPBHK_03473 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
CLFLPBHK_03474 6.9e-27 yflI - - - - - - -
CLFLPBHK_03475 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
CLFLPBHK_03476 3.42e-157 yflK - - S - - - protein conserved in bacteria
CLFLPBHK_03477 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CLFLPBHK_03478 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CLFLPBHK_03479 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CLFLPBHK_03480 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CLFLPBHK_03481 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
CLFLPBHK_03482 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CLFLPBHK_03483 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CLFLPBHK_03484 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CLFLPBHK_03485 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
CLFLPBHK_03486 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
CLFLPBHK_03487 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
CLFLPBHK_03488 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CLFLPBHK_03489 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03490 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CLFLPBHK_03491 1.15e-191 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
CLFLPBHK_03492 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
CLFLPBHK_03493 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
CLFLPBHK_03494 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
CLFLPBHK_03495 5.54e-219 yvlB - - S - - - Putative adhesin
CLFLPBHK_03496 8.09e-65 yvlA - - - - - - -
CLFLPBHK_03497 2.25e-45 yvkN - - - - - - -
CLFLPBHK_03498 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CLFLPBHK_03499 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CLFLPBHK_03500 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CLFLPBHK_03501 2.54e-42 csbA - - S - - - protein conserved in bacteria
CLFLPBHK_03502 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
CLFLPBHK_03503 1.43e-131 yvkB - - K - - - Transcriptional regulator
CLFLPBHK_03504 3.03e-295 yvkA - - P - - - -transporter
CLFLPBHK_03505 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CLFLPBHK_03506 1.38e-73 swrA - - S - - - Swarming motility protein
CLFLPBHK_03507 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CLFLPBHK_03508 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CLFLPBHK_03509 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
CLFLPBHK_03510 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CLFLPBHK_03511 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CLFLPBHK_03512 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CLFLPBHK_03513 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CLFLPBHK_03516 1.88e-09 - - - - - - - -
CLFLPBHK_03518 2.01e-64 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA replication protein
CLFLPBHK_03519 2.79e-87 - - - L - - - dnaD_dom DnaD domain protein
CLFLPBHK_03521 4.59e-23 - - - - - - - -
CLFLPBHK_03522 1.7e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_03523 7.24e-60 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_03527 1.79e-149 - - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_03528 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
CLFLPBHK_03529 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
CLFLPBHK_03530 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CLFLPBHK_03531 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
CLFLPBHK_03532 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CLFLPBHK_03533 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CLFLPBHK_03534 1.96e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
CLFLPBHK_03535 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
CLFLPBHK_03536 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CLFLPBHK_03537 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
CLFLPBHK_03538 8.14e-73 yusE - - CO - - - Thioredoxin
CLFLPBHK_03539 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
CLFLPBHK_03540 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
CLFLPBHK_03541 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CLFLPBHK_03542 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
CLFLPBHK_03543 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CLFLPBHK_03544 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
CLFLPBHK_03545 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
CLFLPBHK_03546 1.11e-13 - - - S - - - YuzL-like protein
CLFLPBHK_03547 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CLFLPBHK_03548 2.23e-54 - - - - - - - -
CLFLPBHK_03549 8.66e-70 yusN - - M - - - Coat F domain
CLFLPBHK_03550 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
CLFLPBHK_03551 0.0 yusP - - P - - - Major facilitator superfamily
CLFLPBHK_03552 4.86e-84 yusQ - - S - - - Tautomerase enzyme
CLFLPBHK_03553 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_03554 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
CLFLPBHK_03555 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
CLFLPBHK_03556 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CLFLPBHK_03557 3.48e-88 - - - S - - - YusW-like protein
CLFLPBHK_03558 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
CLFLPBHK_03560 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CLFLPBHK_03561 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
CLFLPBHK_03562 6.4e-09 - - - J - - - O-methyltransferase
CLFLPBHK_03563 2.94e-17 - - - EGP - - - Major Facilitator
CLFLPBHK_03565 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
CLFLPBHK_03567 1.26e-18 - - - - - - - -
CLFLPBHK_03568 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CLFLPBHK_03569 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_03570 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
CLFLPBHK_03571 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
CLFLPBHK_03572 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
CLFLPBHK_03573 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CLFLPBHK_03574 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CLFLPBHK_03575 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CLFLPBHK_03576 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CLFLPBHK_03577 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
CLFLPBHK_03578 7.55e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
CLFLPBHK_03579 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
CLFLPBHK_03580 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
CLFLPBHK_03582 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CLFLPBHK_03583 5.55e-137 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CLFLPBHK_03584 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CLFLPBHK_03585 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CLFLPBHK_03586 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CLFLPBHK_03587 5.89e-230 yaaC - - S - - - YaaC-like Protein
CLFLPBHK_03588 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CLFLPBHK_03589 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CLFLPBHK_03590 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
CLFLPBHK_03591 2.43e-58 yjcN - - - - - - -
CLFLPBHK_03592 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
CLFLPBHK_03593 1.08e-60 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_03594 1.12e-33 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_03601 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
CLFLPBHK_03602 1.79e-84 ydjM - - M - - - Lytic transglycolase
CLFLPBHK_03603 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
CLFLPBHK_03604 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_03605 1.91e-33 - - - S - - - Ion transport 2 domain protein
CLFLPBHK_03606 4.11e-183 - - - S - - - Ion transport 2 domain protein
CLFLPBHK_03607 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
CLFLPBHK_03608 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
CLFLPBHK_03609 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CLFLPBHK_03610 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
CLFLPBHK_03611 4.95e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
CLFLPBHK_03612 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
CLFLPBHK_03613 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
CLFLPBHK_03614 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
CLFLPBHK_03615 5.53e-175 - - - - - - - -
CLFLPBHK_03616 1.17e-148 - - - - - - - -
CLFLPBHK_03620 5.85e-35 - - - U - - - Preprotein translocase subunit SecB
CLFLPBHK_03622 6.75e-38 - - - K - - - Helix-turn-helix domain
CLFLPBHK_03624 7.52e-55 - - - S - - - protein domain associated with
CLFLPBHK_03626 6.57e-233 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
CLFLPBHK_03627 8.88e-87 - - - S - - - Immunity protein 70
CLFLPBHK_03628 7.81e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CLFLPBHK_03629 3.19e-41 xhlB - - S - - - SPP1 phage holin
CLFLPBHK_03630 1.81e-37 bhlA - - S - - - BhlA holin family
CLFLPBHK_03633 5.85e-165 yebC - - M - - - Membrane
CLFLPBHK_03634 6.6e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CLFLPBHK_03635 1.15e-314 - - - S - - - Domain of unknown function (DUF4179)
CLFLPBHK_03636 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CLFLPBHK_03637 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CLFLPBHK_03638 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
CLFLPBHK_03639 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CLFLPBHK_03640 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
CLFLPBHK_03641 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CLFLPBHK_03642 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CLFLPBHK_03643 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
CLFLPBHK_03644 6.33e-103 yeaA - - S - - - Protein of unknown function (DUF4003)
CLFLPBHK_03645 1.46e-201 - - - I - - - Alpha/beta hydrolase family
CLFLPBHK_03646 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
CLFLPBHK_03648 2.08e-190 yerO - - K - - - Transcriptional regulator
CLFLPBHK_03649 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CLFLPBHK_03650 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CLFLPBHK_03651 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CLFLPBHK_03652 0.0 - - - L - - - Type III restriction enzyme res subunit
CLFLPBHK_03656 1.59e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_03658 5.1e-36 - - - - - - - -
CLFLPBHK_03659 3.39e-98 - - - S - - - Protein of unknown function, DUF600
CLFLPBHK_03660 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
CLFLPBHK_03662 2.44e-127 - - - L - - - endonuclease activity
CLFLPBHK_03663 1.23e-14 - - - S - - - Pfam:DUF1311
CLFLPBHK_03664 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
CLFLPBHK_03666 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
CLFLPBHK_03668 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03669 4.59e-101 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
CLFLPBHK_03670 1.13e-193 yesF - - GM - - - NAD(P)H-binding
CLFLPBHK_03671 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
CLFLPBHK_03672 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
CLFLPBHK_03673 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
CLFLPBHK_03674 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
CLFLPBHK_03675 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
CLFLPBHK_03676 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_03677 7.1e-163 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
CLFLPBHK_03678 1.32e-69 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
CLFLPBHK_03679 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
CLFLPBHK_03680 6.98e-77 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CLFLPBHK_03681 3.57e-120 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CLFLPBHK_03682 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CLFLPBHK_03683 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
CLFLPBHK_03684 0.0 yesS - - K - - - Transcriptional regulator
CLFLPBHK_03685 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
CLFLPBHK_03686 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
CLFLPBHK_03687 4.69e-144 - - - S - - - Protein of unknown function, DUF624
CLFLPBHK_03688 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
CLFLPBHK_03689 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
CLFLPBHK_03690 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
CLFLPBHK_03691 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
CLFLPBHK_03692 2.25e-127 yetA - - - - - - -
CLFLPBHK_03693 0.0 yetA - - - - - - -
CLFLPBHK_03694 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CLFLPBHK_03695 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
CLFLPBHK_03696 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CLFLPBHK_03697 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
CLFLPBHK_03698 3.66e-157 yetF - - S - - - membrane
CLFLPBHK_03699 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
CLFLPBHK_03700 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CLFLPBHK_03701 1.39e-44 - - - - - - - -
CLFLPBHK_03702 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CLFLPBHK_03703 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
CLFLPBHK_03704 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
CLFLPBHK_03705 1.3e-38 yetM - - CH - - - FAD binding domain
CLFLPBHK_03706 5.94e-131 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
CLFLPBHK_03707 1.94e-248 yetN - - S - - - Protein of unknown function (DUF3900)
CLFLPBHK_03708 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CLFLPBHK_03709 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CLFLPBHK_03710 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
CLFLPBHK_03711 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
CLFLPBHK_03712 2.69e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
CLFLPBHK_03713 6.7e-284 yfnE - - S - - - Glycosyltransferase like family 2
CLFLPBHK_03714 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
CLFLPBHK_03715 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_03716 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CLFLPBHK_03717 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
CLFLPBHK_03718 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CLFLPBHK_03719 5.14e-161 yfmS - - NT - - - chemotaxis protein
CLFLPBHK_03720 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CLFLPBHK_03721 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
CLFLPBHK_03722 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
CLFLPBHK_03723 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
CLFLPBHK_03724 2.1e-39 - - - - - - - -
CLFLPBHK_03726 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CLFLPBHK_03727 5.42e-95 ywiB - - S - - - protein conserved in bacteria
CLFLPBHK_03728 3.71e-12 - - - S - - - Bacteriocin subtilosin A
CLFLPBHK_03729 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
CLFLPBHK_03731 5.02e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CLFLPBHK_03732 1.81e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
CLFLPBHK_03733 3.84e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
CLFLPBHK_03734 1.17e-315 - - - L - - - Peptidase, M16
CLFLPBHK_03736 1.31e-303 ywhL - - CO - - - amine dehydrogenase activity
CLFLPBHK_03737 1.57e-96 ywhK - - CO - - - amine dehydrogenase activity
CLFLPBHK_03738 1.72e-156 ywhK - - CO - - - amine dehydrogenase activity
CLFLPBHK_03739 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CLFLPBHK_03741 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
CLFLPBHK_03742 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CLFLPBHK_03743 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CLFLPBHK_03744 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CLFLPBHK_03745 2.1e-64 - - - - - - - -
CLFLPBHK_03746 1.92e-123 ywhD - - S - - - YwhD family
CLFLPBHK_03747 3.29e-154 ywhC - - S - - - Peptidase family M50
CLFLPBHK_03748 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
CLFLPBHK_03749 1.45e-93 ywhA - - K - - - Transcriptional regulator
CLFLPBHK_03750 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CLFLPBHK_03752 1.54e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
CLFLPBHK_03753 1.1e-103 yffB - - K - - - Transcriptional regulator
CLFLPBHK_03754 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
CLFLPBHK_03755 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
CLFLPBHK_03756 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
CLFLPBHK_03757 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
CLFLPBHK_03758 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
CLFLPBHK_03759 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CLFLPBHK_03760 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03761 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
CLFLPBHK_03762 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
CLFLPBHK_03763 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
CLFLPBHK_03764 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
CLFLPBHK_03765 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
CLFLPBHK_03766 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CLFLPBHK_03767 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_03768 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CLFLPBHK_03769 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CLFLPBHK_03770 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
CLFLPBHK_03771 1.09e-18 - - - S - - - Uncharacterized protein YkpC
CLFLPBHK_03772 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
CLFLPBHK_03773 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
CLFLPBHK_03774 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CLFLPBHK_03775 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
CLFLPBHK_03776 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CLFLPBHK_03777 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CLFLPBHK_03778 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CLFLPBHK_03779 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
CLFLPBHK_03780 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
CLFLPBHK_03781 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CLFLPBHK_03782 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CLFLPBHK_03783 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
CLFLPBHK_03784 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CLFLPBHK_03785 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CLFLPBHK_03786 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CLFLPBHK_03787 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CLFLPBHK_03788 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
CLFLPBHK_03789 0.0 - - - - - - - -
CLFLPBHK_03790 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
CLFLPBHK_03792 0.0 - - - D - - - Phage tail tape measure protein
CLFLPBHK_03795 1.46e-33 - - - - - - - -
CLFLPBHK_03797 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLFLPBHK_03798 8.17e-38 - - - S - - - Phage head-tail joining protein
CLFLPBHK_03800 5.45e-13 - - - - - - - -
CLFLPBHK_03801 7.58e-162 - - - S - - - capsid protein
CLFLPBHK_03802 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
CLFLPBHK_03803 1.33e-216 - - - S - - - portal protein
CLFLPBHK_03805 1.19e-179 terL - - S - - - Terminase
CLFLPBHK_03806 3.93e-73 - - - L - - - Terminase, small subunit
CLFLPBHK_03812 1.47e-41 yqkK - - - - - - -
CLFLPBHK_03813 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CLFLPBHK_03814 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
CLFLPBHK_03815 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
CLFLPBHK_03816 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
CLFLPBHK_03817 3.77e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
CLFLPBHK_03818 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CLFLPBHK_03819 8.27e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CLFLPBHK_03820 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
CLFLPBHK_03821 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CLFLPBHK_03822 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CLFLPBHK_03823 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
CLFLPBHK_03824 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
CLFLPBHK_03825 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
CLFLPBHK_03826 8.55e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
CLFLPBHK_03827 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
CLFLPBHK_03828 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
CLFLPBHK_03829 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
CLFLPBHK_03830 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CLFLPBHK_03831 3.12e-192 ypuA - - S - - - Secreted protein
CLFLPBHK_03832 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLFLPBHK_03833 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLFLPBHK_03838 4.02e-205 pre - - D - - - plasmid recombination enzyme
CLFLPBHK_03842 1.82e-232 - - - L - - - Replication protein
CLFLPBHK_03843 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
CLFLPBHK_03844 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
CLFLPBHK_03845 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
CLFLPBHK_03846 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
CLFLPBHK_03847 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
CLFLPBHK_03848 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
CLFLPBHK_03849 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
CLFLPBHK_03850 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CLFLPBHK_03851 1.15e-43 ynzC - - S - - - UPF0291 protein
CLFLPBHK_03852 5.4e-143 yneB - - L - - - resolvase
CLFLPBHK_03853 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CLFLPBHK_03854 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CLFLPBHK_03855 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CLFLPBHK_03856 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
CLFLPBHK_03857 6.31e-173 yndL - - S - - - Replication protein
CLFLPBHK_03860 0.0 yndJ - - S - - - YndJ-like protein
CLFLPBHK_03861 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
CLFLPBHK_03862 2.52e-196 yndG - - S - - - DoxX-like family
CLFLPBHK_03863 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
CLFLPBHK_03864 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CLFLPBHK_03865 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CLFLPBHK_03868 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
CLFLPBHK_03869 8.92e-96 - - - - - - - -
CLFLPBHK_03870 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
CLFLPBHK_03873 2.43e-162 - - - S - - - Domain of unknown function, YrpD
CLFLPBHK_03875 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CLFLPBHK_03878 7.54e-22 - - - - - - - -
CLFLPBHK_03879 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
CLFLPBHK_03881 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CLFLPBHK_03882 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CLFLPBHK_03883 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
CLFLPBHK_03884 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
CLFLPBHK_03885 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CLFLPBHK_03886 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
CLFLPBHK_03887 1.76e-166 - - - T - - - Signal transduction histidine kinase
CLFLPBHK_03888 8.24e-73 - - - T - - - Signal transduction histidine kinase
CLFLPBHK_03889 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
CLFLPBHK_03890 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CLFLPBHK_03892 2.88e-111 yxjI - - S - - - LURP-one-related
CLFLPBHK_03893 2.13e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
CLFLPBHK_03894 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
CLFLPBHK_03895 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CLFLPBHK_03896 1.69e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CLFLPBHK_03897 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CLFLPBHK_03898 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
CLFLPBHK_03899 9.07e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
CLFLPBHK_03900 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CLFLPBHK_03901 1.51e-91 - - - T - - - Domain of unknown function (DUF4163)
CLFLPBHK_03902 2.28e-63 yxiS - - - - - - -
CLFLPBHK_03903 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CLFLPBHK_03904 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CLFLPBHK_03905 9.33e-103 bglS - - M - - - licheninase activity
CLFLPBHK_03906 4.4e-47 bglS - - M - - - licheninase activity
CLFLPBHK_03907 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CLFLPBHK_03908 7.23e-141 - - - - - - - -
CLFLPBHK_03909 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
CLFLPBHK_03910 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CLFLPBHK_03911 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
CLFLPBHK_03914 4.06e-58 yxiJ - - S - - - YxiJ-like protein
CLFLPBHK_03917 1.86e-40 - - - - - - - -
CLFLPBHK_03918 8.21e-50 yxiI - - S - - - Protein of unknown function (DUF2716)
CLFLPBHK_03919 3.42e-173 - - - - - - - -
CLFLPBHK_03922 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
CLFLPBHK_03923 9.7e-68 yxxG - - - - - - -
CLFLPBHK_03924 4.67e-89 yxiG - - - - - - -
CLFLPBHK_03925 4.48e-58 - - - - - - - -
CLFLPBHK_03926 7.13e-100 - - - - - - - -
CLFLPBHK_03927 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
CLFLPBHK_03928 5.06e-175 - - - - - - - -
CLFLPBHK_03930 1.27e-69 - - - - - - - -
CLFLPBHK_03931 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
CLFLPBHK_03932 3.29e-19 yxiJ - - S - - - YxiJ-like protein
CLFLPBHK_03933 0.0 wapA - - M - - - COG3209 Rhs family protein
CLFLPBHK_03934 5.71e-116 yhaK - - S - - - Putative zincin peptidase
CLFLPBHK_03935 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
CLFLPBHK_03936 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
CLFLPBHK_03937 1.74e-54 yhaH - - S - - - YtxH-like protein
CLFLPBHK_03938 3.36e-30 - - - - - - - -
CLFLPBHK_03939 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
CLFLPBHK_03940 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CLFLPBHK_03941 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CLFLPBHK_03942 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
CLFLPBHK_03943 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CLFLPBHK_03944 2.89e-161 ecsC - - S - - - EcsC protein family
CLFLPBHK_03945 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CLFLPBHK_03946 2.7e-312 yhfA - - C - - - membrane
CLFLPBHK_03947 1e-44 - - - C - - - Rubrerythrin
CLFLPBHK_03948 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
CLFLPBHK_03949 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CLFLPBHK_03950 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CLFLPBHK_03951 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
CLFLPBHK_03952 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CLFLPBHK_03953 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_03954 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
CLFLPBHK_03955 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLFLPBHK_03956 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
CLFLPBHK_03958 1.55e-252 yhfE - - G - - - peptidase M42
CLFLPBHK_03959 1.79e-92 - - - S - - - ASCH
CLFLPBHK_03960 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CLFLPBHK_03961 1.63e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CLFLPBHK_03962 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
CLFLPBHK_03963 1.01e-141 yhfK - - GM - - - NmrA-like family
CLFLPBHK_03964 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CLFLPBHK_03966 5.04e-11 ftsK - - D ko:K03466 - ko00000,ko03036 PFAM cell divisionFtsK SpoIIIE
CLFLPBHK_03967 5.83e-38 - - - - - - - -
CLFLPBHK_03970 1.97e-65 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
CLFLPBHK_03971 1.05e-101 - - - L - - - phage terminase small subunit
CLFLPBHK_03972 0.0 - - - S - - - Terminase
CLFLPBHK_03974 1.93e-303 - - - S - - - Phage portal protein
CLFLPBHK_03975 1.52e-155 - - - OU - - - Belongs to the peptidase S14 family
CLFLPBHK_03976 1.72e-261 - - - S - - - capsid protein
CLFLPBHK_03977 1.27e-30 - - - - - - - -
CLFLPBHK_03978 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
CLFLPBHK_03979 3.02e-51 - - - S - - - Phage head-tail joining protein
CLFLPBHK_03980 9.8e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
CLFLPBHK_03982 2.51e-97 - - - S - - - Phage tail tube protein
CLFLPBHK_03985 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_03986 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
CLFLPBHK_03987 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
CLFLPBHK_03989 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
CLFLPBHK_03990 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
CLFLPBHK_03991 1.92e-97 yuxK - - S - - - protein conserved in bacteria
CLFLPBHK_03992 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
CLFLPBHK_03993 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CLFLPBHK_03994 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CLFLPBHK_03995 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
CLFLPBHK_03996 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_03997 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CLFLPBHK_03998 2.33e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CLFLPBHK_03999 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
CLFLPBHK_04000 1.42e-21 - - - - - - - -
CLFLPBHK_04001 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CLFLPBHK_04002 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CLFLPBHK_04003 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CLFLPBHK_04004 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CLFLPBHK_04005 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CLFLPBHK_04006 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CLFLPBHK_04007 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
CLFLPBHK_04008 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
CLFLPBHK_04009 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CLFLPBHK_04010 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_04011 2.1e-94 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
CLFLPBHK_04012 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CLFLPBHK_04013 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
CLFLPBHK_04014 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CLFLPBHK_04015 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CLFLPBHK_04016 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CLFLPBHK_04017 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_04018 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
CLFLPBHK_04019 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
CLFLPBHK_04020 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CLFLPBHK_04021 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_04022 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CLFLPBHK_04023 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
CLFLPBHK_04024 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
CLFLPBHK_04025 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
CLFLPBHK_04026 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
CLFLPBHK_04027 2.85e-215 eamA1 - - EG - - - spore germination
CLFLPBHK_04028 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CLFLPBHK_04029 4.37e-214 ycbM - - T - - - Histidine kinase
CLFLPBHK_04030 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_04031 1.73e-149 - - - S - - - ABC-2 family transporter protein
CLFLPBHK_04032 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
CLFLPBHK_04033 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
CLFLPBHK_04034 2e-169 - - - - - - - -
CLFLPBHK_04035 5.85e-164 - - - - - - - -
CLFLPBHK_04036 2.09e-103 - - - - - - - -
CLFLPBHK_04037 7.6e-12 - - - S - - - Helix-turn-helix domain
CLFLPBHK_04038 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_04039 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
CLFLPBHK_04040 5.33e-85 - - - - - - - -
CLFLPBHK_04041 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
CLFLPBHK_04043 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
CLFLPBHK_04044 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_04045 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
CLFLPBHK_04047 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
CLFLPBHK_04048 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
CLFLPBHK_04049 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CLFLPBHK_04050 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CLFLPBHK_04051 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
CLFLPBHK_04052 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
CLFLPBHK_04053 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_04054 6.31e-51 - - - - - - - -
CLFLPBHK_04055 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CLFLPBHK_04056 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
CLFLPBHK_04059 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
CLFLPBHK_04061 1.51e-18 cotW - - - ko:K06341 - ko00000 -
CLFLPBHK_04062 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
CLFLPBHK_04063 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
CLFLPBHK_04064 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
CLFLPBHK_04065 2.09e-103 yjbX - - S - - - Spore coat protein
CLFLPBHK_04066 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
CLFLPBHK_04067 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CLFLPBHK_04068 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CLFLPBHK_04069 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CLFLPBHK_04070 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
CLFLPBHK_04071 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
CLFLPBHK_04072 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
CLFLPBHK_04073 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CLFLPBHK_04074 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CLFLPBHK_04075 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CLFLPBHK_04076 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CLFLPBHK_04077 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CLFLPBHK_04078 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
CLFLPBHK_04079 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
CLFLPBHK_04080 7.02e-128 yjbK - - S - - - protein conserved in bacteria
CLFLPBHK_04081 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CLFLPBHK_04082 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
CLFLPBHK_04083 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CLFLPBHK_04084 2.68e-28 - - - - - - - -
CLFLPBHK_04085 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
CLFLPBHK_04086 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
CLFLPBHK_04087 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CLFLPBHK_04088 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
CLFLPBHK_04089 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CLFLPBHK_04090 1.41e-63 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_04091 2.77e-54 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_04092 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
CLFLPBHK_04093 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_04094 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_04095 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_04096 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_04097 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CLFLPBHK_04098 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
CLFLPBHK_04099 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
CLFLPBHK_04100 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_04101 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CLFLPBHK_04102 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
CLFLPBHK_04103 2.82e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_04104 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CLFLPBHK_04105 9.48e-193 yjaZ - - O - - - Zn-dependent protease
CLFLPBHK_04106 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CLFLPBHK_04107 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CLFLPBHK_04108 2.67e-38 yjzB - - - - - - -
CLFLPBHK_04109 8.86e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
CLFLPBHK_04110 5.26e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
CLFLPBHK_04111 5.2e-132 yjaV - - - - - - -
CLFLPBHK_04112 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
CLFLPBHK_04113 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
CLFLPBHK_04114 2.51e-39 yjzC - - S - - - YjzC-like protein
CLFLPBHK_04115 2.23e-90 - - - S - - - Regulatory protein YrvL
CLFLPBHK_04116 9.3e-126 ymcC - - S - - - Membrane
CLFLPBHK_04117 1.02e-134 pksA - - K - - - Transcriptional regulator
CLFLPBHK_04118 8.03e-81 ymzB - - - - - - -
CLFLPBHK_04119 1.96e-209 - - - S - - - Metallo-beta-lactamase superfamily
CLFLPBHK_04120 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
CLFLPBHK_04122 3.96e-163 ymaC - - S - - - Replication protein
CLFLPBHK_04123 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
CLFLPBHK_04124 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
CLFLPBHK_04125 2.45e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CLFLPBHK_04127 5.41e-76 ymaF - - S - - - YmaF family
CLFLPBHK_04128 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CLFLPBHK_04129 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CLFLPBHK_04130 1.63e-31 - - - - - - - -
CLFLPBHK_04131 1.2e-30 ymzA - - - - - - -
CLFLPBHK_04132 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
CLFLPBHK_04133 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLFLPBHK_04134 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CLFLPBHK_04135 2.24e-141 - - - - - - - -
CLFLPBHK_04136 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_04137 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
CLFLPBHK_04138 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CLFLPBHK_04139 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CLFLPBHK_04140 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
CLFLPBHK_04141 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CLFLPBHK_04142 3.69e-32 - - - - - - - -
CLFLPBHK_04143 1.68e-53 - - - - - - - -
CLFLPBHK_04144 4.6e-309 - - - M - - - nucleic acid phosphodiester bond hydrolysis
CLFLPBHK_04146 1.68e-13 - - - - - - - -
CLFLPBHK_04148 1.46e-105 - - - - - - - -
CLFLPBHK_04149 4.13e-51 - - - - - - - -
CLFLPBHK_04150 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
CLFLPBHK_04151 9.3e-51 ynaC - - - - - - -
CLFLPBHK_04152 3.65e-81 ynaC - - - - - - -
CLFLPBHK_04153 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
CLFLPBHK_04154 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CLFLPBHK_04155 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CLFLPBHK_04156 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
CLFLPBHK_04157 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CLFLPBHK_04158 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CLFLPBHK_04159 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CLFLPBHK_04160 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
CLFLPBHK_04161 3.42e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CLFLPBHK_04162 5.98e-72 ypuD - - - - - - -
CLFLPBHK_04163 1.54e-121 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CLFLPBHK_04165 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
CLFLPBHK_04167 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CLFLPBHK_04169 3.82e-37 - - - - - - - -
CLFLPBHK_04170 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
CLFLPBHK_04172 8.16e-77 - - - O - - - Papain family cysteine protease
CLFLPBHK_04173 1.73e-13 - - - - - - - -
CLFLPBHK_04174 0.000711 - - - - - - - -
CLFLPBHK_04177 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLFLPBHK_04178 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CLFLPBHK_04179 4.84e-85 - - - S - - - damaged DNA binding
CLFLPBHK_04180 2.34e-14 - - - S - - - YolD-like protein
CLFLPBHK_04183 1.06e-127 - - - J - - - Acetyltransferase (GNAT) domain
CLFLPBHK_04184 7.01e-129 yokK - - S - - - SMI1 / KNR4 family
CLFLPBHK_04185 3.18e-101 - - - S - - - SMI1-KNR4 cell-wall
CLFLPBHK_04186 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
CLFLPBHK_04187 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CLFLPBHK_04188 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
CLFLPBHK_04189 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
CLFLPBHK_04190 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
CLFLPBHK_04191 5.45e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
CLFLPBHK_04192 2.81e-178 - - - J - - - FR47-like protein
CLFLPBHK_04193 6.23e-127 yobS - - K - - - Transcriptional regulator
CLFLPBHK_04194 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CLFLPBHK_04195 4.8e-111 - - - K - - - Bacterial transcription activator, effector binding domain
CLFLPBHK_04196 1.73e-221 yobV - - K - - - WYL domain
CLFLPBHK_04197 7.38e-121 yobW - - - - - - -
CLFLPBHK_04198 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
CLFLPBHK_04199 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CLFLPBHK_04201 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
CLFLPBHK_04202 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CLFLPBHK_04203 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CLFLPBHK_04204 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
CLFLPBHK_04205 1.74e-222 ykuO - - - - - - -
CLFLPBHK_04206 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
CLFLPBHK_04207 7.61e-215 ccpC - - K - - - Transcriptional regulator
CLFLPBHK_04208 6.01e-99 ykuL - - S - - - CBS domain
CLFLPBHK_04209 7.83e-38 ykzF - - S - - - Antirepressor AbbA
CLFLPBHK_04210 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
CLFLPBHK_04211 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
CLFLPBHK_04212 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
CLFLPBHK_04213 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CLFLPBHK_04214 1.42e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
CLFLPBHK_04215 5.84e-115 ykuD - - S - - - protein conserved in bacteria
CLFLPBHK_04216 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CLFLPBHK_04217 3.71e-110 ykyB - - S - - - YkyB-like protein
CLFLPBHK_04218 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
CLFLPBHK_04219 1.05e-22 - - - - - - - -
CLFLPBHK_04220 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CLFLPBHK_04221 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CLFLPBHK_04222 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CLFLPBHK_04223 6.98e-279 - - - L - - - Transposase
CLFLPBHK_04224 4.78e-152 - - - L - - - Bacterial dnaA protein
CLFLPBHK_04227 1.79e-74 - - - S - - - Bacteriophage holin family
CLFLPBHK_04228 5.27e-142 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_04231 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
CLFLPBHK_04234 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CLFLPBHK_04235 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
CLFLPBHK_04236 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
CLFLPBHK_04237 1.94e-95 yvaD - - S - - - Family of unknown function (DUF5360)
CLFLPBHK_04238 0.0 - - - S - - - Fusaric acid resistance protein-like
CLFLPBHK_04239 7.68e-25 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLFLPBHK_04240 2.92e-88 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CLFLPBHK_04241 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CLFLPBHK_04242 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
CLFLPBHK_04243 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
CLFLPBHK_04244 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CLFLPBHK_04245 3.57e-33 - - - - - - - -
CLFLPBHK_04246 2e-32 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
CLFLPBHK_04247 2.18e-75 - - - S - - - Bacteriophage holin family
CLFLPBHK_04248 2.39e-158 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CLFLPBHK_04249 6.62e-36 - - - S - - - Domain of unknown function (DUF4917)
CLFLPBHK_04251 2.51e-13 - - - - - - - -
CLFLPBHK_04252 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
CLFLPBHK_04253 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
CLFLPBHK_04254 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CLFLPBHK_04255 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CLFLPBHK_04256 1.04e-122 gerD - - - ko:K06294 - ko00000 -
CLFLPBHK_04257 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
CLFLPBHK_04258 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
CLFLPBHK_04259 5.95e-306 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CLFLPBHK_04260 2.29e-29 ywtC - - - - - - -
CLFLPBHK_04261 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CLFLPBHK_04262 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
CLFLPBHK_04263 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
CLFLPBHK_04264 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
CLFLPBHK_04265 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CLFLPBHK_04266 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CLFLPBHK_04267 8.71e-176 yphF - - - - - - -
CLFLPBHK_04268 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
CLFLPBHK_04269 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CLFLPBHK_04270 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CLFLPBHK_04271 2.06e-38 ypzH - - - - - - -
CLFLPBHK_04272 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
CLFLPBHK_04273 1.11e-133 yphA - - - - - - -
CLFLPBHK_04274 1.13e-11 - - - S - - - YpzI-like protein
CLFLPBHK_04275 2.61e-15 - - - S - - - Protein of unknown function (DUF1433)
CLFLPBHK_04276 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
CLFLPBHK_04278 1.93e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CLFLPBHK_04279 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CLFLPBHK_04280 5.43e-52 ykoA - - - - - - -
CLFLPBHK_04281 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CLFLPBHK_04282 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CLFLPBHK_04283 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
CLFLPBHK_04284 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
CLFLPBHK_04285 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CLFLPBHK_04286 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CLFLPBHK_04287 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CLFLPBHK_04288 1.31e-150 yknW - - S - - - Yip1 domain
CLFLPBHK_04289 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CLFLPBHK_04290 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CLFLPBHK_04291 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CLFLPBHK_04292 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
CLFLPBHK_04293 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
CLFLPBHK_04294 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
CLFLPBHK_04295 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CLFLPBHK_04296 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CLFLPBHK_04297 9.46e-198 yknT - - - ko:K06437 - ko00000 -
CLFLPBHK_04298 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CLFLPBHK_04299 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
CLFLPBHK_04300 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
CLFLPBHK_04301 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CLFLPBHK_04302 2.45e-23 - - - S - - - YrzO-like protein
CLFLPBHK_04303 3.17e-212 yrdR - - EG - - - EamA-like transporter family
CLFLPBHK_04304 1.4e-203 - - - K - - - Transcriptional regulator
CLFLPBHK_04305 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
CLFLPBHK_04306 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
CLFLPBHK_04311 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
CLFLPBHK_04312 5.71e-121 - - - M - - - FR47-like protein
CLFLPBHK_04313 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
CLFLPBHK_04314 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
CLFLPBHK_04315 6.53e-108 yuaE - - S - - - DinB superfamily
CLFLPBHK_04316 7.66e-99 - - - - - - - -
CLFLPBHK_04317 3.2e-59 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
CLFLPBHK_04318 4.46e-23 - - - - - - - -
CLFLPBHK_04320 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CLFLPBHK_04322 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CLFLPBHK_04323 0.000849 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
CLFLPBHK_04324 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
CLFLPBHK_04325 2.14e-17 - - - Q - - - methyltransferase
CLFLPBHK_04327 3.25e-72 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CLFLPBHK_04328 4.43e-68 acdA - - I - - - acyl-CoA dehydrogenase
CLFLPBHK_04329 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
CLFLPBHK_04331 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CLFLPBHK_04363 2.47e-268 VCP - - O - - - AAA domain (dynein-related subfamily)
CLFLPBHK_04364 2.71e-103 yjoA - - S - - - DinB family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)