ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PIBGAFCF_00001 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
PIBGAFCF_00002 1.15e-06 - - - - - - - -
PIBGAFCF_00003 1.9e-109 - - - S - - - Protein of unknown function (DUF2815)
PIBGAFCF_00004 4.71e-203 - - - L - - - Protein of unknown function (DUF2800)
PIBGAFCF_00005 3.53e-17 - - - - - - - -
PIBGAFCF_00006 1.52e-58 - - - - - - - -
PIBGAFCF_00008 1.1e-42 - - - S - - - Uncharacterized protein YqaH
PIBGAFCF_00010 1.05e-40 - - - - - - - -
PIBGAFCF_00011 1.35e-26 - - - - - - - -
PIBGAFCF_00012 1.89e-68 - - - K - - - Cro/C1-type HTH DNA-binding domain
PIBGAFCF_00013 5.95e-72 - - - E - - - IrrE N-terminal-like domain
PIBGAFCF_00014 3.69e-192 - - - S - - - Pfam:Arm-DNA-bind_4
PIBGAFCF_00015 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
PIBGAFCF_00016 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
PIBGAFCF_00017 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIBGAFCF_00018 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PIBGAFCF_00019 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PIBGAFCF_00021 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PIBGAFCF_00022 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PIBGAFCF_00023 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
PIBGAFCF_00024 1.24e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIBGAFCF_00025 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
PIBGAFCF_00026 2.25e-70 yusE - - CO - - - Thioredoxin
PIBGAFCF_00027 5.93e-30 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
PIBGAFCF_00028 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
PIBGAFCF_00029 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PIBGAFCF_00030 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PIBGAFCF_00031 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PIBGAFCF_00032 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
PIBGAFCF_00033 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
PIBGAFCF_00034 1.72e-10 - - - S - - - YuzL-like protein
PIBGAFCF_00035 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PIBGAFCF_00036 7.03e-53 - - - - - - - -
PIBGAFCF_00037 3.53e-69 yusN - - M - - - Coat F domain
PIBGAFCF_00038 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
PIBGAFCF_00039 0.0 yusP - - P - - - Major facilitator superfamily
PIBGAFCF_00040 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
PIBGAFCF_00041 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_00042 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PIBGAFCF_00043 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
PIBGAFCF_00044 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PIBGAFCF_00045 2.79e-62 - - - S - - - YusW-like protein
PIBGAFCF_00046 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
PIBGAFCF_00047 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_00048 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PIBGAFCF_00049 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIBGAFCF_00050 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_00051 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_00052 2.68e-32 - - - - - - - -
PIBGAFCF_00053 6.7e-196 yuxN - - K - - - Transcriptional regulator
PIBGAFCF_00054 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIBGAFCF_00055 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
PIBGAFCF_00056 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PIBGAFCF_00057 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PIBGAFCF_00058 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
PIBGAFCF_00059 2.48e-134 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIBGAFCF_00060 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_00061 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
PIBGAFCF_00062 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PIBGAFCF_00063 6.99e-127 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PIBGAFCF_00064 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
PIBGAFCF_00065 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_00066 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
PIBGAFCF_00067 1.87e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PIBGAFCF_00068 5.73e-224 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_00069 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PIBGAFCF_00070 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_00071 9.6e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
PIBGAFCF_00072 0.0 yvrG - - T - - - Histidine kinase
PIBGAFCF_00073 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_00074 1.14e-48 - - - - - - - -
PIBGAFCF_00075 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PIBGAFCF_00076 1.88e-21 - - - S - - - YvrJ protein family
PIBGAFCF_00077 1.65e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PIBGAFCF_00078 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
PIBGAFCF_00079 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PIBGAFCF_00080 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_00081 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_00082 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PIBGAFCF_00083 4.36e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PIBGAFCF_00084 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
PIBGAFCF_00085 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
PIBGAFCF_00086 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
PIBGAFCF_00087 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PIBGAFCF_00088 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PIBGAFCF_00089 1.97e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
PIBGAFCF_00090 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
PIBGAFCF_00091 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
PIBGAFCF_00092 2.17e-146 yfiK - - K - - - Regulator
PIBGAFCF_00093 3.01e-237 - - - T - - - Histidine kinase
PIBGAFCF_00094 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PIBGAFCF_00095 3e-234 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PIBGAFCF_00096 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PIBGAFCF_00097 1.77e-200 yvgN - - S - - - reductase
PIBGAFCF_00098 1.55e-110 yvgO - - - - - - -
PIBGAFCF_00099 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
PIBGAFCF_00100 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PIBGAFCF_00101 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PIBGAFCF_00102 3.26e-144 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PIBGAFCF_00103 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PIBGAFCF_00104 6.1e-128 yvgT - - S - - - membrane
PIBGAFCF_00105 5.24e-188 - - - S - - - Metallo-peptidase family M12
PIBGAFCF_00106 5.06e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
PIBGAFCF_00107 2.51e-135 bdbD - - O - - - Thioredoxin
PIBGAFCF_00108 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PIBGAFCF_00109 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PIBGAFCF_00110 9.29e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
PIBGAFCF_00111 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
PIBGAFCF_00112 4.69e-238 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PIBGAFCF_00113 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIBGAFCF_00114 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_00115 4.4e-29 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
PIBGAFCF_00116 7.09e-226 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_00117 1.18e-176 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PIBGAFCF_00118 5.33e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PIBGAFCF_00119 1.35e-152 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PIBGAFCF_00120 1.8e-181 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PIBGAFCF_00121 3.28e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
PIBGAFCF_00122 5.25e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PIBGAFCF_00123 4.27e-201 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
PIBGAFCF_00124 1.18e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_00125 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PIBGAFCF_00126 1.83e-09 - - - - - - - -
PIBGAFCF_00127 8.17e-31 - - - - - - - -
PIBGAFCF_00129 2.51e-86 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
PIBGAFCF_00130 1.37e-86 - - - S - - - Pfam:Phage_holin_4_1
PIBGAFCF_00133 8.27e-229 - - - S - - - Domain of unknown function (DUF2479)
PIBGAFCF_00134 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
PIBGAFCF_00135 1.33e-259 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PIBGAFCF_00136 2.17e-138 - - - S - - - Phage tail protein
PIBGAFCF_00137 0.0 - - - S - - - peptidoglycan catabolic process
PIBGAFCF_00138 1.78e-16 - - - - - - - -
PIBGAFCF_00139 1.65e-31 - - - - - - - -
PIBGAFCF_00140 3.6e-76 - - - - - - - -
PIBGAFCF_00141 2.86e-40 - - - - - - - -
PIBGAFCF_00142 3.61e-61 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PIBGAFCF_00143 4.36e-20 - - - S - - - Phage head-tail joining protein
PIBGAFCF_00144 2.01e-31 - - - S - - - Phage gp6-like head-tail connector protein
PIBGAFCF_00145 4.59e-57 - - - S - - - peptidoglycan catabolic process
PIBGAFCF_00146 7.43e-09 - - - - - - - -
PIBGAFCF_00147 8.05e-226 - - - S - - - capsid protein
PIBGAFCF_00148 5.48e-143 - - - S - - - peptidase activity
PIBGAFCF_00149 2.44e-305 - - - S - - - Phage portal protein
PIBGAFCF_00150 1.56e-14 - - - - - - - -
PIBGAFCF_00151 3.71e-289 - - - S - - - Phage Terminase
PIBGAFCF_00152 1.85e-110 - - - S - - - Phage terminase, small subunit
PIBGAFCF_00153 3.03e-28 - - - - - - - -
PIBGAFCF_00154 8.48e-88 - - - S - - - HNH endonuclease
PIBGAFCF_00157 3.02e-99 - - - L - - - Phage integrase family
PIBGAFCF_00158 4.1e-70 - - - M - - - ArpU family transcriptional regulator
PIBGAFCF_00159 8.16e-07 - - - - - - - -
PIBGAFCF_00160 1.09e-61 - - - - - - - -
PIBGAFCF_00166 1.65e-104 - - - S - - - dUTPase
PIBGAFCF_00169 1.18e-127 - - - H - - - C-5 cytosine-specific DNA methylase
PIBGAFCF_00170 8.03e-70 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PIBGAFCF_00171 5.04e-201 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
PIBGAFCF_00172 2.17e-56 ymxH - - S - - - YlmC YmxH family
PIBGAFCF_00173 9.39e-296 mlpA - - S - - - Belongs to the peptidase M16 family
PIBGAFCF_00174 1.33e-228 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
PIBGAFCF_00175 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PIBGAFCF_00176 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIBGAFCF_00177 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PIBGAFCF_00178 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIBGAFCF_00179 2.38e-67 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIBGAFCF_00180 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
PIBGAFCF_00181 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIBGAFCF_00182 6.16e-63 ylxQ - - J - - - ribosomal protein
PIBGAFCF_00183 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
PIBGAFCF_00184 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PIBGAFCF_00185 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PIBGAFCF_00186 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIBGAFCF_00187 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIBGAFCF_00188 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PIBGAFCF_00189 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PIBGAFCF_00190 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PIBGAFCF_00191 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIBGAFCF_00192 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIBGAFCF_00193 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PIBGAFCF_00194 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIBGAFCF_00195 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PIBGAFCF_00196 2.54e-84 ylxL - - - - - - -
PIBGAFCF_00197 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_00198 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PIBGAFCF_00199 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PIBGAFCF_00200 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
PIBGAFCF_00201 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
PIBGAFCF_00202 2.95e-241 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PIBGAFCF_00203 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
PIBGAFCF_00204 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
PIBGAFCF_00205 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PIBGAFCF_00206 1.34e-237 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PIBGAFCF_00207 1.06e-163 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
PIBGAFCF_00208 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
PIBGAFCF_00209 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
PIBGAFCF_00210 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
PIBGAFCF_00211 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
PIBGAFCF_00212 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PIBGAFCF_00213 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PIBGAFCF_00214 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
PIBGAFCF_00215 1.04e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
PIBGAFCF_00216 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
PIBGAFCF_00217 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
PIBGAFCF_00218 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
PIBGAFCF_00219 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PIBGAFCF_00220 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PIBGAFCF_00221 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
PIBGAFCF_00222 4.78e-227 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PIBGAFCF_00223 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
PIBGAFCF_00224 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
PIBGAFCF_00225 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
PIBGAFCF_00226 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PIBGAFCF_00227 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PIBGAFCF_00228 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIBGAFCF_00229 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIBGAFCF_00230 2.96e-213 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
PIBGAFCF_00231 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIBGAFCF_00232 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIBGAFCF_00233 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
PIBGAFCF_00234 1.26e-212 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PIBGAFCF_00235 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PIBGAFCF_00236 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
PIBGAFCF_00237 0.0 ylqG - - - - - - -
PIBGAFCF_00238 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIBGAFCF_00239 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIBGAFCF_00240 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIBGAFCF_00241 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PIBGAFCF_00242 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIBGAFCF_00243 5.66e-79 ylqD - - S - - - YlqD protein
PIBGAFCF_00244 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PIBGAFCF_00245 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PIBGAFCF_00246 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIBGAFCF_00247 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIBGAFCF_00248 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIBGAFCF_00249 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PIBGAFCF_00250 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIBGAFCF_00251 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIBGAFCF_00252 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PIBGAFCF_00253 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PIBGAFCF_00254 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIBGAFCF_00255 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PIBGAFCF_00256 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIBGAFCF_00257 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PIBGAFCF_00258 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PIBGAFCF_00259 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PIBGAFCF_00260 6.07e-77 yloU - - S - - - protein conserved in bacteria
PIBGAFCF_00261 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PIBGAFCF_00262 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PIBGAFCF_00263 4.85e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PIBGAFCF_00264 6.97e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIBGAFCF_00265 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PIBGAFCF_00266 4.92e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PIBGAFCF_00267 7.22e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PIBGAFCF_00268 2.98e-315 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIBGAFCF_00269 3.85e-214 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIBGAFCF_00270 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIBGAFCF_00271 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIBGAFCF_00272 2e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIBGAFCF_00273 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIBGAFCF_00274 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PIBGAFCF_00275 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
PIBGAFCF_00276 8e-194 yloC - - S - - - stress-induced protein
PIBGAFCF_00277 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
PIBGAFCF_00278 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PIBGAFCF_00279 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PIBGAFCF_00280 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
PIBGAFCF_00281 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
PIBGAFCF_00282 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PIBGAFCF_00283 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PIBGAFCF_00284 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PIBGAFCF_00285 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
PIBGAFCF_00286 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PIBGAFCF_00287 1e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIBGAFCF_00288 1.17e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIBGAFCF_00289 2.36e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIBGAFCF_00290 6.57e-177 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PIBGAFCF_00291 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
PIBGAFCF_00292 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PIBGAFCF_00293 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIBGAFCF_00294 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PIBGAFCF_00295 1e-289 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
PIBGAFCF_00296 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIBGAFCF_00297 2.09e-213 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PIBGAFCF_00298 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIBGAFCF_00299 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
PIBGAFCF_00300 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIBGAFCF_00301 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PIBGAFCF_00302 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
PIBGAFCF_00303 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
PIBGAFCF_00304 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIBGAFCF_00305 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PIBGAFCF_00306 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
PIBGAFCF_00307 7.13e-52 ylmC - - S - - - sporulation protein
PIBGAFCF_00308 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
PIBGAFCF_00309 8.63e-182 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PIBGAFCF_00310 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_00311 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_00312 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PIBGAFCF_00313 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
PIBGAFCF_00314 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIBGAFCF_00315 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIBGAFCF_00316 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIBGAFCF_00317 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PIBGAFCF_00318 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIBGAFCF_00319 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PIBGAFCF_00320 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIBGAFCF_00321 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIBGAFCF_00322 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIBGAFCF_00323 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
PIBGAFCF_00324 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PIBGAFCF_00325 2.81e-67 ftsL - - D - - - Essential cell division protein
PIBGAFCF_00326 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIBGAFCF_00327 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PIBGAFCF_00328 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PIBGAFCF_00329 4.46e-190 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIBGAFCF_00330 2.68e-115 ylbP - - K - - - n-acetyltransferase
PIBGAFCF_00331 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PIBGAFCF_00332 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PIBGAFCF_00333 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PIBGAFCF_00334 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
PIBGAFCF_00335 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PIBGAFCF_00336 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PIBGAFCF_00337 8.16e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
PIBGAFCF_00338 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIBGAFCF_00339 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PIBGAFCF_00340 4.62e-56 ylbG - - S - - - UPF0298 protein
PIBGAFCF_00341 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
PIBGAFCF_00342 1.73e-48 ylbE - - S - - - YlbE-like protein
PIBGAFCF_00343 5.5e-83 ylbD - - S - - - Putative coat protein
PIBGAFCF_00344 9.62e-247 ylbC - - S - - - protein with SCP PR1 domains
PIBGAFCF_00345 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
PIBGAFCF_00346 1.33e-75 ylbA - - S - - - YugN-like family
PIBGAFCF_00347 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
PIBGAFCF_00348 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PIBGAFCF_00349 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PIBGAFCF_00350 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PIBGAFCF_00351 1.61e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PIBGAFCF_00352 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PIBGAFCF_00353 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PIBGAFCF_00354 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PIBGAFCF_00355 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PIBGAFCF_00356 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
PIBGAFCF_00357 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PIBGAFCF_00358 4.45e-104 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PIBGAFCF_00359 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PIBGAFCF_00360 2.67e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIBGAFCF_00361 7.95e-45 ylaI - - S - - - protein conserved in bacteria
PIBGAFCF_00362 1.41e-64 - - - S - - - YlaH-like protein
PIBGAFCF_00363 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PIBGAFCF_00364 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
PIBGAFCF_00365 1.97e-52 ylaE - - - - - - -
PIBGAFCF_00367 9.3e-32 ylaA - - - - - - -
PIBGAFCF_00368 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PIBGAFCF_00369 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
PIBGAFCF_00370 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
PIBGAFCF_00371 7.89e-32 ykzI - - - - - - -
PIBGAFCF_00372 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
PIBGAFCF_00373 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
PIBGAFCF_00374 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
PIBGAFCF_00375 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PIBGAFCF_00376 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PIBGAFCF_00377 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIBGAFCF_00378 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIBGAFCF_00379 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIBGAFCF_00380 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIBGAFCF_00381 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
PIBGAFCF_00382 1.04e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PIBGAFCF_00383 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIBGAFCF_00384 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
PIBGAFCF_00385 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
PIBGAFCF_00386 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIBGAFCF_00387 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PIBGAFCF_00388 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PIBGAFCF_00389 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
PIBGAFCF_00390 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PIBGAFCF_00391 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
PIBGAFCF_00392 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
PIBGAFCF_00393 7.7e-19 - - - S - - - Uncharacterized protein YkpC
PIBGAFCF_00394 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PIBGAFCF_00395 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIBGAFCF_00396 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIBGAFCF_00397 3.54e-48 ykoA - - - - - - -
PIBGAFCF_00398 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PIBGAFCF_00399 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PIBGAFCF_00400 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
PIBGAFCF_00401 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00402 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PIBGAFCF_00403 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_00404 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PIBGAFCF_00405 5.77e-134 yknW - - S - - - Yip1 domain
PIBGAFCF_00406 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PIBGAFCF_00407 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
PIBGAFCF_00408 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
PIBGAFCF_00409 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
PIBGAFCF_00410 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PIBGAFCF_00411 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PIBGAFCF_00412 8.39e-201 yknT - - - ko:K06437 - ko00000 -
PIBGAFCF_00413 3.55e-125 rok - - K - - - Repressor of ComK
PIBGAFCF_00415 1.9e-93 ykuV - - CO - - - thiol-disulfide
PIBGAFCF_00417 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
PIBGAFCF_00418 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
PIBGAFCF_00419 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIBGAFCF_00420 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIBGAFCF_00421 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
PIBGAFCF_00422 1.07e-207 ykuO - - - - - - -
PIBGAFCF_00423 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
PIBGAFCF_00424 1.08e-214 ccpC - - K - - - Transcriptional regulator
PIBGAFCF_00425 8.55e-99 ykuL - - S - - - CBS domain
PIBGAFCF_00426 2.63e-36 ykzF - - S - - - Antirepressor AbbA
PIBGAFCF_00427 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
PIBGAFCF_00428 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
PIBGAFCF_00429 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
PIBGAFCF_00431 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_00432 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
PIBGAFCF_00433 3.48e-114 ykuD - - S - - - protein conserved in bacteria
PIBGAFCF_00434 2e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_00435 1.45e-107 ykyB - - S - - - YkyB-like protein
PIBGAFCF_00436 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
PIBGAFCF_00437 2.22e-15 - - - - - - - -
PIBGAFCF_00438 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PIBGAFCF_00439 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_00440 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PIBGAFCF_00441 9.82e-167 ykwD - - J - - - protein with SCP PR1 domains
PIBGAFCF_00442 9.19e-65 - - - - - - - -
PIBGAFCF_00443 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PIBGAFCF_00444 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PIBGAFCF_00445 3.25e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
PIBGAFCF_00446 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00447 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIBGAFCF_00448 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
PIBGAFCF_00449 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_00450 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
PIBGAFCF_00451 4.21e-217 ykvZ - - K - - - Transcriptional regulator
PIBGAFCF_00452 5.05e-258 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PIBGAFCF_00453 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PIBGAFCF_00454 1.04e-105 stoA - - CO - - - thiol-disulfide
PIBGAFCF_00455 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_00456 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
PIBGAFCF_00457 8.76e-38 - - - - - - - -
PIBGAFCF_00458 1.56e-34 ykvS - - S - - - protein conserved in bacteria
PIBGAFCF_00459 5.82e-53 ykvR - - S - - - Protein of unknown function (DUF3219)
PIBGAFCF_00460 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PIBGAFCF_00461 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PIBGAFCF_00462 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PIBGAFCF_00463 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PIBGAFCF_00464 1.81e-196 - - - - - - - -
PIBGAFCF_00466 6.18e-222 ykvI - - S - - - membrane
PIBGAFCF_00467 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
PIBGAFCF_00468 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PIBGAFCF_00469 5.44e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PIBGAFCF_00470 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
PIBGAFCF_00471 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PIBGAFCF_00473 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PIBGAFCF_00474 1.9e-139 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PIBGAFCF_00475 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PIBGAFCF_00476 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PIBGAFCF_00477 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PIBGAFCF_00478 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PIBGAFCF_00479 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PIBGAFCF_00480 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PIBGAFCF_00482 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIBGAFCF_00483 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_00484 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
PIBGAFCF_00485 1.37e-26 ykzE - - - - - - -
PIBGAFCF_00486 1.59e-143 - - - S - - - Protein of unknown function (DUF421)
PIBGAFCF_00487 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
PIBGAFCF_00488 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PIBGAFCF_00489 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
PIBGAFCF_00490 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
PIBGAFCF_00491 1.17e-219 ykrI - - S - - - Anti-sigma factor N-terminus
PIBGAFCF_00492 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_00493 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PIBGAFCF_00494 1.21e-123 ykoX - - S - - - membrane-associated protein
PIBGAFCF_00495 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
PIBGAFCF_00496 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PIBGAFCF_00497 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
PIBGAFCF_00498 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
PIBGAFCF_00499 1.15e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
PIBGAFCF_00500 3.57e-35 ykoL - - - - - - -
PIBGAFCF_00501 2.24e-23 - - - - - - - -
PIBGAFCF_00502 3.53e-69 tnrA - - K - - - transcriptional
PIBGAFCF_00503 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
PIBGAFCF_00505 4.54e-303 ydhD - - M - - - Glycosyl hydrolase
PIBGAFCF_00506 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PIBGAFCF_00507 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_00508 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PIBGAFCF_00509 2.08e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIBGAFCF_00510 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PIBGAFCF_00511 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PIBGAFCF_00512 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PIBGAFCF_00513 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_00514 8.96e-151 - - - K - - - Collagen triple helix repeat
PIBGAFCF_00515 2.15e-260 - - - M - - - Glycosyl transferase family 2
PIBGAFCF_00517 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIBGAFCF_00518 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
PIBGAFCF_00519 1.55e-36 ohrR - - K - - - COG1846 Transcriptional regulators
PIBGAFCF_00520 2.88e-41 ohrR - - K - - - COG1846 Transcriptional regulators
PIBGAFCF_00521 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
PIBGAFCF_00522 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PIBGAFCF_00523 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIBGAFCF_00524 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PIBGAFCF_00525 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
PIBGAFCF_00526 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
PIBGAFCF_00527 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PIBGAFCF_00528 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
PIBGAFCF_00529 1.45e-179 ykgA - - E - - - Amidinotransferase
PIBGAFCF_00530 6.11e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
PIBGAFCF_00531 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00532 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PIBGAFCF_00533 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PIBGAFCF_00534 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
PIBGAFCF_00535 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PIBGAFCF_00536 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00537 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00538 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00539 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
PIBGAFCF_00540 0.0 yubD - - P - - - Major Facilitator Superfamily
PIBGAFCF_00541 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIBGAFCF_00543 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PIBGAFCF_00544 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PIBGAFCF_00545 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PIBGAFCF_00546 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
PIBGAFCF_00547 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
PIBGAFCF_00548 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
PIBGAFCF_00549 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
PIBGAFCF_00550 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
PIBGAFCF_00551 2.43e-206 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_00552 2.62e-49 xhlB - - S - - - SPP1 phage holin
PIBGAFCF_00553 6.44e-50 xhlA - - S - - - Haemolysin XhlA
PIBGAFCF_00554 2.97e-167 xepA - - - - - - -
PIBGAFCF_00555 1.05e-36 xkdX - - - - - - -
PIBGAFCF_00557 1.04e-194 - - - - - - - -
PIBGAFCF_00558 1.48e-36 - - - - - - - -
PIBGAFCF_00559 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PIBGAFCF_00560 7.44e-208 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PIBGAFCF_00561 2.35e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
PIBGAFCF_00562 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
PIBGAFCF_00563 2.78e-208 xkdQ - - G - - - NLP P60 protein
PIBGAFCF_00564 1.25e-144 xkdP - - S - - - Lysin motif
PIBGAFCF_00565 3.8e-245 xkdO - - L - - - Transglycosylase SLT domain
PIBGAFCF_00566 4.33e-27 - - - - - - - -
PIBGAFCF_00567 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
PIBGAFCF_00568 8.21e-97 xkdM - - S - - - Phage tail tube protein
PIBGAFCF_00569 4.44e-285 xkdK - - S - - - Phage tail sheath C-terminal domain
PIBGAFCF_00570 3.86e-21 - - - - - - - -
PIBGAFCF_00571 1.82e-75 xkdJ - - - - - - -
PIBGAFCF_00572 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
PIBGAFCF_00574 8.84e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
PIBGAFCF_00575 3.38e-202 xkdG - - S - - - Phage capsid family
PIBGAFCF_00576 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
PIBGAFCF_00577 9.96e-302 xkdE3 - - S - - - portal protein
PIBGAFCF_00578 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
PIBGAFCF_00579 1.37e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
PIBGAFCF_00580 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PIBGAFCF_00584 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
PIBGAFCF_00586 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_00587 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
PIBGAFCF_00588 2.69e-128 yjqB - - S - - - phage-related replication protein
PIBGAFCF_00589 3.19e-79 yjqA - - S - - - Bacterial PH domain
PIBGAFCF_00590 5.72e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PIBGAFCF_00592 5.18e-273 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PIBGAFCF_00593 9.4e-100 yjoA - - S - - - DinB family
PIBGAFCF_00594 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
PIBGAFCF_00596 2.46e-48 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PIBGAFCF_00597 2.99e-104 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PIBGAFCF_00598 9.74e-43 - - - T - - - Transcriptional regulatory protein, C terminal
PIBGAFCF_00599 1.25e-55 - - - T - - - Transcriptional regulatory protein, C terminal
PIBGAFCF_00600 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PIBGAFCF_00601 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
PIBGAFCF_00602 2.92e-80 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
PIBGAFCF_00603 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PIBGAFCF_00604 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
PIBGAFCF_00605 1.47e-110 yjlB - - S - - - Cupin domain
PIBGAFCF_00606 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
PIBGAFCF_00607 4.5e-159 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00608 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
PIBGAFCF_00609 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PIBGAFCF_00610 1.73e-40 - - - - - - - -
PIBGAFCF_00611 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PIBGAFCF_00612 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PIBGAFCF_00613 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
PIBGAFCF_00614 2.62e-157 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
PIBGAFCF_00615 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
PIBGAFCF_00616 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
PIBGAFCF_00617 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
PIBGAFCF_00618 1.07e-28 yjfB - - S - - - Putative motility protein
PIBGAFCF_00620 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PIBGAFCF_00621 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_00622 3.81e-45 - - - - - - - -
PIBGAFCF_00623 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
PIBGAFCF_00624 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PIBGAFCF_00625 2.12e-106 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_00626 1.19e-198 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_00627 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_00628 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIBGAFCF_00629 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
PIBGAFCF_00630 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_00631 5.5e-302 yfjF - - EGP - - - Belongs to the major facilitator superfamily
PIBGAFCF_00632 7.1e-58 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
PIBGAFCF_00633 3.78e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
PIBGAFCF_00635 4.57e-21 - - - N - - - Kelch motif
PIBGAFCF_00636 0.000667 KLHL36 - - T ko:K13958 - ko00000,ko04121 protein modification by small protein conjugation
PIBGAFCF_00640 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
PIBGAFCF_00641 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIBGAFCF_00642 9.18e-49 - - - S - - - YolD-like protein
PIBGAFCF_00643 0.0 - - - K - - - Psort location Cytoplasmic, score
PIBGAFCF_00644 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
PIBGAFCF_00646 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
PIBGAFCF_00647 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
PIBGAFCF_00648 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
PIBGAFCF_00649 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
PIBGAFCF_00650 1.06e-42 - - - - - - - -
PIBGAFCF_00651 2.31e-90 - - - S - - - Bacterial EndoU nuclease
PIBGAFCF_00652 2.03e-64 - - - - - - - -
PIBGAFCF_00654 1.19e-41 - - - S - - - KTSC domain
PIBGAFCF_00655 1.11e-13 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PIBGAFCF_00656 2.38e-153 - - - D - - - phage tail tape measure protein
PIBGAFCF_00657 2.88e-47 - - - D - - - phage tail tape measure protein
PIBGAFCF_00664 1.53e-25 - - - - - - - -
PIBGAFCF_00665 7.77e-110 - - - - - - - -
PIBGAFCF_00672 1.05e-32 - - - - - - - -
PIBGAFCF_00673 2.38e-18 - - - S - - - Cro/C1-type HTH DNA-binding domain
PIBGAFCF_00676 5.56e-100 - - - N - - - bacterial-type flagellum assembly
PIBGAFCF_00677 8.56e-120 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
PIBGAFCF_00678 6.97e-134 - - - S - - - Helix-turn-helix domain
PIBGAFCF_00679 4.81e-253 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
PIBGAFCF_00681 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PIBGAFCF_00682 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PIBGAFCF_00683 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
PIBGAFCF_00684 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
PIBGAFCF_00685 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIBGAFCF_00686 1.19e-45 - - - K - - - SpoVT / AbrB like domain
PIBGAFCF_00687 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PIBGAFCF_00688 1.16e-153 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PIBGAFCF_00689 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PIBGAFCF_00690 1.62e-44 - - - - - - - -
PIBGAFCF_00691 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PIBGAFCF_00692 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
PIBGAFCF_00693 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PIBGAFCF_00696 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
PIBGAFCF_00697 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
PIBGAFCF_00698 1.02e-36 cotW - - - ko:K06341 - ko00000 -
PIBGAFCF_00699 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
PIBGAFCF_00700 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
PIBGAFCF_00701 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
PIBGAFCF_00702 2.47e-100 yjbX - - S - - - Spore coat protein
PIBGAFCF_00703 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PIBGAFCF_00704 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PIBGAFCF_00705 1.17e-226 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PIBGAFCF_00706 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PIBGAFCF_00707 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
PIBGAFCF_00708 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
PIBGAFCF_00709 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
PIBGAFCF_00710 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PIBGAFCF_00711 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PIBGAFCF_00712 1.1e-176 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PIBGAFCF_00713 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PIBGAFCF_00714 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIBGAFCF_00715 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
PIBGAFCF_00716 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
PIBGAFCF_00717 8.1e-118 yjbK - - S - - - protein conserved in bacteria
PIBGAFCF_00718 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PIBGAFCF_00719 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
PIBGAFCF_00720 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PIBGAFCF_00721 3.14e-27 - - - - - - - -
PIBGAFCF_00722 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PIBGAFCF_00723 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
PIBGAFCF_00724 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PIBGAFCF_00725 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
PIBGAFCF_00726 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIBGAFCF_00727 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIBGAFCF_00728 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
PIBGAFCF_00729 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00730 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00731 2.95e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00732 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00733 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PIBGAFCF_00734 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PIBGAFCF_00735 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
PIBGAFCF_00736 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00737 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00738 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
PIBGAFCF_00739 4.48e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00740 1.81e-226 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00741 2.47e-179 yjaZ - - O - - - Zn-dependent protease
PIBGAFCF_00742 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIBGAFCF_00743 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIBGAFCF_00744 1.46e-37 yjzB - - - - - - -
PIBGAFCF_00745 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
PIBGAFCF_00746 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
PIBGAFCF_00747 7.04e-127 yjaV - - - - - - -
PIBGAFCF_00748 6.32e-169 yjaU - - I - - - carboxylic ester hydrolase activity
PIBGAFCF_00749 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
PIBGAFCF_00750 2.07e-38 yjzC - - S - - - YjzC-like protein
PIBGAFCF_00751 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PIBGAFCF_00752 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
PIBGAFCF_00753 9.26e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PIBGAFCF_00754 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PIBGAFCF_00755 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PIBGAFCF_00756 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PIBGAFCF_00757 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PIBGAFCF_00758 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
PIBGAFCF_00759 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
PIBGAFCF_00760 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PIBGAFCF_00761 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
PIBGAFCF_00762 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PIBGAFCF_00763 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PIBGAFCF_00764 1.49e-11 - - - - - - - -
PIBGAFCF_00765 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
PIBGAFCF_00766 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
PIBGAFCF_00767 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_00768 8.05e-196 yitS - - S - - - protein conserved in bacteria
PIBGAFCF_00769 4.22e-293 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
PIBGAFCF_00770 1.06e-288 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PIBGAFCF_00771 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
PIBGAFCF_00772 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
PIBGAFCF_00773 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
PIBGAFCF_00774 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PIBGAFCF_00775 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
PIBGAFCF_00776 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
PIBGAFCF_00777 1.72e-232 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIBGAFCF_00778 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
PIBGAFCF_00779 3.26e-100 yisT - - S - - - DinB family
PIBGAFCF_00780 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PIBGAFCF_00781 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PIBGAFCF_00782 1.77e-201 yisR - - K - - - Transcriptional regulator
PIBGAFCF_00783 9.76e-307 yisQ - - V - - - Mate efflux family protein
PIBGAFCF_00784 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
PIBGAFCF_00785 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PIBGAFCF_00786 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
PIBGAFCF_00787 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PIBGAFCF_00788 4.48e-78 yisL - - S - - - UPF0344 protein
PIBGAFCF_00789 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PIBGAFCF_00790 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
PIBGAFCF_00791 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
PIBGAFCF_00792 7.71e-42 gerPB - - S ko:K06300 - ko00000 cell differentiation
PIBGAFCF_00793 9.39e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
PIBGAFCF_00794 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
PIBGAFCF_00795 2.37e-77 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
PIBGAFCF_00796 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
PIBGAFCF_00797 8.91e-64 yisB - - V - - - COG1403 Restriction endonuclease
PIBGAFCF_00798 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PIBGAFCF_00799 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PIBGAFCF_00800 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PIBGAFCF_00801 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
PIBGAFCF_00802 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
PIBGAFCF_00803 3.47e-108 yhjR - - S - - - Rubrerythrin
PIBGAFCF_00804 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
PIBGAFCF_00805 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_00806 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
PIBGAFCF_00807 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_00808 0.0 yhjG - - CH - - - FAD binding domain
PIBGAFCF_00809 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PIBGAFCF_00810 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
PIBGAFCF_00811 2.3e-76 yhjD - - - - - - -
PIBGAFCF_00812 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
PIBGAFCF_00813 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIBGAFCF_00814 2.64e-63 - - - S - - - Belongs to the UPF0145 family
PIBGAFCF_00815 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
PIBGAFCF_00816 3.92e-157 yrpD - - S - - - Domain of unknown function, YrpD
PIBGAFCF_00817 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
PIBGAFCF_00818 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PIBGAFCF_00819 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
PIBGAFCF_00820 5.49e-42 yhzC - - S - - - IDEAL
PIBGAFCF_00821 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_00822 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PIBGAFCF_00823 2.43e-271 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
PIBGAFCF_00824 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PIBGAFCF_00825 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PIBGAFCF_00826 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PIBGAFCF_00827 4.57e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
PIBGAFCF_00828 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PIBGAFCF_00829 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PIBGAFCF_00830 1.33e-293 yhfN - - O - - - Peptidase M48
PIBGAFCF_00831 9.31e-84 yhfM - - - - - - -
PIBGAFCF_00832 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PIBGAFCF_00833 3.92e-137 yhfK - - GM - - - NmrA-like family
PIBGAFCF_00834 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PIBGAFCF_00835 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PIBGAFCF_00836 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIBGAFCF_00837 1.66e-247 yhfE - - G - - - peptidase M42
PIBGAFCF_00839 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIBGAFCF_00840 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
PIBGAFCF_00841 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00842 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PIBGAFCF_00843 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PIBGAFCF_00844 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PIBGAFCF_00845 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PIBGAFCF_00846 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PIBGAFCF_00847 1.65e-303 yhfA - - C - - - membrane
PIBGAFCF_00848 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PIBGAFCF_00849 9.96e-152 ecsC - - S - - - EcsC protein family
PIBGAFCF_00850 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PIBGAFCF_00851 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
PIBGAFCF_00852 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PIBGAFCF_00853 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PIBGAFCF_00854 5.77e-96 trpP - - S - - - Tryptophan transporter TrpP
PIBGAFCF_00855 2.55e-24 - - - - - - - -
PIBGAFCF_00856 1.58e-53 yhaH - - S - - - YtxH-like protein
PIBGAFCF_00857 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
PIBGAFCF_00858 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
PIBGAFCF_00859 4.32e-122 yhaK - - S - - - Putative zincin peptidase
PIBGAFCF_00860 3.2e-182 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIBGAFCF_00861 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
PIBGAFCF_00862 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
PIBGAFCF_00863 0.0 yhaN - - L - - - AAA domain
PIBGAFCF_00864 3.8e-293 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
PIBGAFCF_00865 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
PIBGAFCF_00866 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_00867 1.21e-20 - - - S - - - YhzD-like protein
PIBGAFCF_00868 4.59e-172 yhaR - - I - - - enoyl-CoA hydratase
PIBGAFCF_00870 6.25e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PIBGAFCF_00871 9.07e-263 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
PIBGAFCF_00872 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
PIBGAFCF_00873 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
PIBGAFCF_00874 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
PIBGAFCF_00875 5.48e-69 yheA - - S - - - Belongs to the UPF0342 family
PIBGAFCF_00876 8.97e-254 yheB - - S - - - Belongs to the UPF0754 family
PIBGAFCF_00877 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
PIBGAFCF_00878 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
PIBGAFCF_00879 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
PIBGAFCF_00880 3.86e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
PIBGAFCF_00882 9.64e-127 yheG - - GM - - - NAD(P)H-binding
PIBGAFCF_00883 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PIBGAFCF_00884 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PIBGAFCF_00885 3.96e-107 - - - T - - - universal stress protein
PIBGAFCF_00886 1.17e-118 ymcC - - S - - - Membrane
PIBGAFCF_00887 9.13e-126 pksA - - K - - - Transcriptional regulator
PIBGAFCF_00888 1.05e-191 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PIBGAFCF_00889 6.85e-192 nodB1 - - G - - - deacetylase
PIBGAFCF_00890 3.53e-172 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PIBGAFCF_00891 5.39e-252 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
PIBGAFCF_00892 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
PIBGAFCF_00893 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PIBGAFCF_00894 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIBGAFCF_00895 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIBGAFCF_00896 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
PIBGAFCF_00897 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIBGAFCF_00898 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PIBGAFCF_00899 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
PIBGAFCF_00900 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PIBGAFCF_00901 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PIBGAFCF_00902 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_00903 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
PIBGAFCF_00904 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
PIBGAFCF_00905 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PIBGAFCF_00906 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
PIBGAFCF_00907 3.42e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_00908 3.63e-249 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PIBGAFCF_00909 1.7e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00910 2.28e-166 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PIBGAFCF_00911 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PIBGAFCF_00912 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
PIBGAFCF_00913 2.06e-41 ygxB - - M - - - Conserved TM helix
PIBGAFCF_00914 1.77e-226 ygxB - - M - - - Conserved TM helix
PIBGAFCF_00915 1.49e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
PIBGAFCF_00916 1.69e-282 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PIBGAFCF_00917 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
PIBGAFCF_00918 1.16e-51 yhdB - - S - - - YhdB-like protein
PIBGAFCF_00919 2.89e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
PIBGAFCF_00920 1.88e-137 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIBGAFCF_00921 1.11e-246 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_00922 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PIBGAFCF_00923 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PIBGAFCF_00924 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIBGAFCF_00925 5.86e-92 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PIBGAFCF_00926 1.23e-84 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PIBGAFCF_00927 2.26e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PIBGAFCF_00928 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIBGAFCF_00929 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PIBGAFCF_00930 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
PIBGAFCF_00931 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
PIBGAFCF_00932 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
PIBGAFCF_00933 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PIBGAFCF_00934 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PIBGAFCF_00935 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PIBGAFCF_00936 2.2e-149 yhcQ - - M - - - Spore coat protein
PIBGAFCF_00937 1.63e-198 yhcP - - - - - - -
PIBGAFCF_00938 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIBGAFCF_00939 5.08e-60 yhcM - - - - - - -
PIBGAFCF_00940 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PIBGAFCF_00941 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIBGAFCF_00942 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
PIBGAFCF_00943 6.9e-161 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PIBGAFCF_00944 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
PIBGAFCF_00945 7.61e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PIBGAFCF_00946 3.59e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_00947 8.89e-147 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_00948 3.06e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00949 7.54e-65 - - - - - - - -
PIBGAFCF_00950 1.03e-65 yhcC - - - - - - -
PIBGAFCF_00951 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PIBGAFCF_00952 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
PIBGAFCF_00953 1.21e-129 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
PIBGAFCF_00954 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
PIBGAFCF_00955 2.12e-276 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
PIBGAFCF_00956 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
PIBGAFCF_00957 1.23e-07 - - - - - - - -
PIBGAFCF_00958 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PIBGAFCF_00959 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PIBGAFCF_00960 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
PIBGAFCF_00961 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIBGAFCF_00962 8.37e-216 yhbB - - S - - - Putative amidase domain
PIBGAFCF_00963 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PIBGAFCF_00964 1.34e-138 yhzB - - S - - - B3/4 domain
PIBGAFCF_00966 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_00967 2.81e-101 ygaO - - - - - - -
PIBGAFCF_00968 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIBGAFCF_00970 1.37e-269 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
PIBGAFCF_00971 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PIBGAFCF_00972 2.34e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
PIBGAFCF_00973 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PIBGAFCF_00974 1.61e-225 - - - S ko:K07045 - ko00000 Amidohydrolase
PIBGAFCF_00975 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PIBGAFCF_00976 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00977 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_00978 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIBGAFCF_00979 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PIBGAFCF_00980 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
PIBGAFCF_00982 3.15e-313 ygaK - - C - - - Berberine and berberine like
PIBGAFCF_00983 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PIBGAFCF_00984 2.38e-158 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PIBGAFCF_00985 0.0 - - - C - - - Na+/H+ antiporter family
PIBGAFCF_01004 1.31e-20 yqaO - - S - - - Phage-like element PBSX protein XtrA
PIBGAFCF_01005 2.19e-05 - - - - - - - -
PIBGAFCF_01008 2.97e-36 - - - - - - - -
PIBGAFCF_01009 3.73e-11 - - - - - - - -
PIBGAFCF_01011 4.95e-22 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
PIBGAFCF_01012 5.17e-100 - - - L - - - dnaD_dom DnaD domain protein
PIBGAFCF_01014 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
PIBGAFCF_01015 1.84e-18 - - - S - - - sequence-specific DNA binding
PIBGAFCF_01016 2.7e-07 - - - K - - - Helix-turn-helix domain protein
PIBGAFCF_01017 6.93e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_01019 1.03e-84 - - - - - - - -
PIBGAFCF_01020 5.51e-162 - - - S - - - Phage integrase family
PIBGAFCF_01022 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PIBGAFCF_01023 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIBGAFCF_01024 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
PIBGAFCF_01025 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PIBGAFCF_01026 1.64e-47 yvzC - - K - - - transcriptional
PIBGAFCF_01027 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PIBGAFCF_01028 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PIBGAFCF_01029 1.17e-67 yvaP - - K - - - transcriptional
PIBGAFCF_01030 3.51e-308 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
PIBGAFCF_01031 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PIBGAFCF_01032 1.93e-167 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PIBGAFCF_01033 1.35e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PIBGAFCF_01034 1.73e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_01035 4.05e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PIBGAFCF_01036 4.75e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIBGAFCF_01037 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PIBGAFCF_01038 1.39e-259 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PIBGAFCF_01039 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PIBGAFCF_01040 2.08e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PIBGAFCF_01041 6.03e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIBGAFCF_01042 3.12e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PIBGAFCF_01043 7.33e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PIBGAFCF_01044 1.88e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PIBGAFCF_01045 4.44e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PIBGAFCF_01046 5.38e-142 yvbI - - M - - - Membrane
PIBGAFCF_01047 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PIBGAFCF_01048 1.24e-103 yvbK - - K - - - acetyltransferase
PIBGAFCF_01049 4.16e-260 - - - EGP - - - Major facilitator Superfamily
PIBGAFCF_01050 1.87e-219 - - - - - - - -
PIBGAFCF_01051 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
PIBGAFCF_01052 1.13e-182 - - - C - - - WbqC-like protein family
PIBGAFCF_01053 2.49e-179 - - - M - - - Protein involved in cellulose biosynthesis
PIBGAFCF_01054 5.44e-278 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PIBGAFCF_01055 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
PIBGAFCF_01056 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PIBGAFCF_01057 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PIBGAFCF_01058 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
PIBGAFCF_01059 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIBGAFCF_01060 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
PIBGAFCF_01061 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIBGAFCF_01062 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PIBGAFCF_01063 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIBGAFCF_01064 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PIBGAFCF_01066 1.08e-270 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIBGAFCF_01067 2.91e-256 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
PIBGAFCF_01068 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_01069 3.86e-18 yvbU - - K - - - Transcriptional regulator
PIBGAFCF_01070 2.18e-124 yvbU - - K - - - Transcriptional regulator
PIBGAFCF_01071 5.35e-196 yvbV - - EG - - - EamA-like transporter family
PIBGAFCF_01072 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_01074 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
PIBGAFCF_01075 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PIBGAFCF_01076 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PIBGAFCF_01077 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PIBGAFCF_01078 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PIBGAFCF_01079 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PIBGAFCF_01080 2.07e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIBGAFCF_01081 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PIBGAFCF_01082 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PIBGAFCF_01083 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PIBGAFCF_01084 4.01e-44 yvfG - - S - - - YvfG protein
PIBGAFCF_01085 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
PIBGAFCF_01086 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PIBGAFCF_01087 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PIBGAFCF_01088 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PIBGAFCF_01089 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_01090 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PIBGAFCF_01091 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
PIBGAFCF_01092 8.53e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PIBGAFCF_01093 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
PIBGAFCF_01094 1.95e-253 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PIBGAFCF_01095 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
PIBGAFCF_01096 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
PIBGAFCF_01097 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PIBGAFCF_01098 8.95e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PIBGAFCF_01099 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
PIBGAFCF_01100 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
PIBGAFCF_01101 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PIBGAFCF_01103 8.3e-111 ywjB - - H - - - RibD C-terminal domain
PIBGAFCF_01104 4.2e-164 - - - CH - - - FAD binding domain
PIBGAFCF_01105 3.18e-97 glx2 - - S - - - Metallo-beta-lactamase superfamily
PIBGAFCF_01106 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
PIBGAFCF_01107 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIBGAFCF_01108 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PIBGAFCF_01109 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
PIBGAFCF_01110 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
PIBGAFCF_01111 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
PIBGAFCF_01112 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
PIBGAFCF_01113 0.0 - - - I - - - Pfam Lipase (class 3)
PIBGAFCF_01114 3.08e-44 - - - - - - - -
PIBGAFCF_01116 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PIBGAFCF_01117 1.69e-277 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
PIBGAFCF_01118 2.68e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
PIBGAFCF_01119 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIBGAFCF_01120 1.4e-202 yraN - - K - - - Transcriptional regulator
PIBGAFCF_01121 3.16e-258 yraM - - S - - - PrpF protein
PIBGAFCF_01122 6.64e-313 - - - EGP - - - Sugar (and other) transporter
PIBGAFCF_01123 1.06e-110 - - - - - - - -
PIBGAFCF_01124 1.25e-56 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PIBGAFCF_01125 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
PIBGAFCF_01126 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PIBGAFCF_01127 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PIBGAFCF_01128 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIBGAFCF_01129 4.11e-100 - - - M - - - Ribonuclease
PIBGAFCF_01130 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
PIBGAFCF_01131 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
PIBGAFCF_01132 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PIBGAFCF_01133 3.01e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PIBGAFCF_01134 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PIBGAFCF_01135 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PIBGAFCF_01136 6.06e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIBGAFCF_01137 7.8e-192 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
PIBGAFCF_01138 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
PIBGAFCF_01139 1.01e-231 sasA - - T - - - Histidine kinase
PIBGAFCF_01140 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_01141 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PIBGAFCF_01142 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
PIBGAFCF_01143 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PIBGAFCF_01144 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PIBGAFCF_01145 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PIBGAFCF_01146 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PIBGAFCF_01147 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PIBGAFCF_01148 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PIBGAFCF_01149 9.79e-260 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PIBGAFCF_01150 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
PIBGAFCF_01151 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PIBGAFCF_01152 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PIBGAFCF_01153 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIBGAFCF_01154 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIBGAFCF_01155 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIBGAFCF_01156 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIBGAFCF_01157 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
PIBGAFCF_01158 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PIBGAFCF_01159 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
PIBGAFCF_01160 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
PIBGAFCF_01161 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PIBGAFCF_01162 4.14e-214 yvlB - - S - - - Putative adhesin
PIBGAFCF_01163 1.79e-61 yvlA - - - - - - -
PIBGAFCF_01164 1.29e-40 yvkN - - - - - - -
PIBGAFCF_01165 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIBGAFCF_01166 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIBGAFCF_01167 2.59e-45 csbA - - S - - - protein conserved in bacteria
PIBGAFCF_01168 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
PIBGAFCF_01169 1.12e-119 yvkB - - K - - - Transcriptional regulator
PIBGAFCF_01170 4.95e-290 yvkA - - P - - - -transporter
PIBGAFCF_01173 1.39e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIBGAFCF_01174 5.83e-72 swrA - - S - - - Swarming motility protein
PIBGAFCF_01175 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PIBGAFCF_01176 1.35e-271 ywoF - - P - - - Right handed beta helix region
PIBGAFCF_01177 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PIBGAFCF_01178 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PIBGAFCF_01179 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PIBGAFCF_01180 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_01181 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIBGAFCF_01182 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIBGAFCF_01183 1.73e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIBGAFCF_01184 1.92e-89 - - - - - - - -
PIBGAFCF_01185 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
PIBGAFCF_01186 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
PIBGAFCF_01187 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PIBGAFCF_01188 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PIBGAFCF_01189 2.2e-42 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PIBGAFCF_01190 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PIBGAFCF_01191 1.27e-104 yviE - - - - - - -
PIBGAFCF_01192 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
PIBGAFCF_01193 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
PIBGAFCF_01194 1.43e-101 yvyG - - NOU - - - FlgN protein
PIBGAFCF_01195 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
PIBGAFCF_01196 6.15e-95 yvyF - - S - - - flagellar protein
PIBGAFCF_01197 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
PIBGAFCF_01198 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
PIBGAFCF_01199 5.41e-316 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PIBGAFCF_01200 3.16e-197 degV - - S - - - protein conserved in bacteria
PIBGAFCF_01201 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIBGAFCF_01202 5.43e-244 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PIBGAFCF_01203 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
PIBGAFCF_01204 9.24e-234 yvhJ - - K - - - Transcriptional regulator
PIBGAFCF_01205 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PIBGAFCF_01206 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
PIBGAFCF_01207 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PIBGAFCF_01208 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
PIBGAFCF_01209 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
PIBGAFCF_01210 2.38e-309 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PIBGAFCF_01211 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
PIBGAFCF_01212 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_01213 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PIBGAFCF_01214 5.41e-269 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_01215 0.0 lytB - - D - - - Stage II sporulation protein
PIBGAFCF_01216 1.99e-39 - - - - - - - -
PIBGAFCF_01217 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PIBGAFCF_01218 8.48e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIBGAFCF_01219 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PIBGAFCF_01220 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PIBGAFCF_01221 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PIBGAFCF_01222 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PIBGAFCF_01223 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
PIBGAFCF_01224 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
PIBGAFCF_01225 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PIBGAFCF_01226 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PIBGAFCF_01227 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIBGAFCF_01228 9.18e-204 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PIBGAFCF_01229 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PIBGAFCF_01230 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PIBGAFCF_01231 1.04e-216 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
PIBGAFCF_01232 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
PIBGAFCF_01233 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIBGAFCF_01234 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
PIBGAFCF_01235 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PIBGAFCF_01236 1.4e-60 yttA - - S - - - Pfam Transposase IS66
PIBGAFCF_01237 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PIBGAFCF_01238 1.16e-28 ywtC - - - - - - -
PIBGAFCF_01239 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PIBGAFCF_01240 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
PIBGAFCF_01241 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
PIBGAFCF_01242 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
PIBGAFCF_01243 1.4e-227 - - - E - - - Spore germination protein
PIBGAFCF_01244 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
PIBGAFCF_01245 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
PIBGAFCF_01246 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
PIBGAFCF_01247 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIBGAFCF_01248 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIBGAFCF_01249 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PIBGAFCF_01250 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PIBGAFCF_01251 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
PIBGAFCF_01252 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
PIBGAFCF_01253 2.39e-115 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
PIBGAFCF_01254 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PIBGAFCF_01255 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PIBGAFCF_01256 6.98e-211 alsR - - K - - - LysR substrate binding domain
PIBGAFCF_01257 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PIBGAFCF_01258 8.96e-150 ywrJ - - - - - - -
PIBGAFCF_01259 4.38e-157 cotB - - - ko:K06325 - ko00000 -
PIBGAFCF_01260 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
PIBGAFCF_01261 9.99e-10 - - - - - - - -
PIBGAFCF_01262 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PIBGAFCF_01264 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PIBGAFCF_01265 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PIBGAFCF_01266 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
PIBGAFCF_01267 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
PIBGAFCF_01268 1.29e-130 - - - - - - - -
PIBGAFCF_01269 7.15e-83 - - - - - - - -
PIBGAFCF_01270 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
PIBGAFCF_01271 1.92e-25 - - - - - - - -
PIBGAFCF_01272 2.19e-75 - - - S - - - SUKH-4 immunity protein
PIBGAFCF_01273 2.72e-95 ywqJ - - S - - - Pre-toxin TG
PIBGAFCF_01274 3.03e-133 ywqJ - - S - - - Pre-toxin TG
PIBGAFCF_01275 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
PIBGAFCF_01277 3.03e-183 ywqG - - S - - - Domain of unknown function (DUF1963)
PIBGAFCF_01278 9.97e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PIBGAFCF_01279 4.63e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
PIBGAFCF_01280 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PIBGAFCF_01281 8.45e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
PIBGAFCF_01282 3e-22 - - - - - - - -
PIBGAFCF_01283 0.0 ywqB - - S - - - SWIM zinc finger
PIBGAFCF_01284 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PIBGAFCF_01285 1.28e-193 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PIBGAFCF_01286 5.39e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
PIBGAFCF_01287 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PIBGAFCF_01288 1.83e-74 ywpG - - - - - - -
PIBGAFCF_01289 1.79e-89 ywpF - - S - - - YwpF-like protein
PIBGAFCF_01290 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIBGAFCF_01291 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIBGAFCF_01292 3.62e-246 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
PIBGAFCF_01293 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PIBGAFCF_01294 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PIBGAFCF_01295 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
PIBGAFCF_01296 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
PIBGAFCF_01297 5.3e-93 ywoH - - K - - - transcriptional
PIBGAFCF_01298 1.12e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_01299 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
PIBGAFCF_01300 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
PIBGAFCF_01301 2.1e-128 yjgF - - Q - - - Isochorismatase family
PIBGAFCF_01302 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
PIBGAFCF_01303 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PIBGAFCF_01304 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PIBGAFCF_01305 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
PIBGAFCF_01306 3.41e-88 ywnJ - - S - - - VanZ like family
PIBGAFCF_01307 1.67e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PIBGAFCF_01308 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
PIBGAFCF_01310 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
PIBGAFCF_01311 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIBGAFCF_01312 1.12e-21 yqgA - - - - - - -
PIBGAFCF_01313 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
PIBGAFCF_01314 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PIBGAFCF_01315 3.09e-88 ywnA - - K - - - Transcriptional regulator
PIBGAFCF_01316 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PIBGAFCF_01317 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
PIBGAFCF_01318 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
PIBGAFCF_01319 2.21e-15 csbD - - K - - - CsbD-like
PIBGAFCF_01320 1.01e-105 ywmF - - S - - - Peptidase M50
PIBGAFCF_01321 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PIBGAFCF_01322 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PIBGAFCF_01323 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PIBGAFCF_01325 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PIBGAFCF_01326 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PIBGAFCF_01327 1.97e-231 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
PIBGAFCF_01328 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIBGAFCF_01329 1.27e-169 ywmB - - S - - - TATA-box binding
PIBGAFCF_01330 1.85e-44 ywzB - - S - - - membrane
PIBGAFCF_01331 1.98e-115 ywmA - - - - - - -
PIBGAFCF_01332 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PIBGAFCF_01333 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIBGAFCF_01334 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIBGAFCF_01335 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIBGAFCF_01336 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIBGAFCF_01337 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIBGAFCF_01338 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIBGAFCF_01339 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PIBGAFCF_01340 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
PIBGAFCF_01341 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIBGAFCF_01342 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIBGAFCF_01343 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
PIBGAFCF_01344 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
PIBGAFCF_01345 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIBGAFCF_01346 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
PIBGAFCF_01347 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIBGAFCF_01348 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
PIBGAFCF_01349 1.73e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
PIBGAFCF_01350 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PIBGAFCF_01352 2.91e-195 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIBGAFCF_01353 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIBGAFCF_01354 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_01355 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PIBGAFCF_01356 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PIBGAFCF_01357 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PIBGAFCF_01358 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PIBGAFCF_01359 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PIBGAFCF_01360 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PIBGAFCF_01361 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
PIBGAFCF_01362 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIBGAFCF_01363 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PIBGAFCF_01364 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
PIBGAFCF_01365 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
PIBGAFCF_01366 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
PIBGAFCF_01367 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIBGAFCF_01368 1.32e-72 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIBGAFCF_01369 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PIBGAFCF_01370 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PIBGAFCF_01371 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PIBGAFCF_01372 1.32e-57 ywjC - - - - - - -
PIBGAFCF_01373 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
PIBGAFCF_01374 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIBGAFCF_01375 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
PIBGAFCF_01376 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
PIBGAFCF_01377 6.59e-59 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
PIBGAFCF_01378 4.79e-299 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
PIBGAFCF_01379 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIBGAFCF_01380 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
PIBGAFCF_01381 8.59e-162 ywiC - - S - - - YwiC-like protein
PIBGAFCF_01382 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
PIBGAFCF_01383 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PIBGAFCF_01384 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PIBGAFCF_01385 4.46e-94 ywiB - - S - - - protein conserved in bacteria
PIBGAFCF_01387 2.2e-248 ywhL - - CO - - - amine dehydrogenase activity
PIBGAFCF_01388 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PIBGAFCF_01390 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PIBGAFCF_01391 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PIBGAFCF_01392 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PIBGAFCF_01393 1.96e-93 - - - - - - - -
PIBGAFCF_01394 2.07e-116 ywhD - - S - - - YwhD family
PIBGAFCF_01395 1.29e-151 ywhC - - S - - - Peptidase family M50
PIBGAFCF_01396 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
PIBGAFCF_01397 3.29e-90 ywhA - - K - - - Transcriptional regulator
PIBGAFCF_01398 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
PIBGAFCF_01399 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
PIBGAFCF_01400 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
PIBGAFCF_01401 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
PIBGAFCF_01402 3.27e-136 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
PIBGAFCF_01403 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
PIBGAFCF_01404 2.51e-109 - - - S - - - membrane
PIBGAFCF_01405 1.93e-194 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_01406 4.3e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
PIBGAFCF_01409 1.87e-209 - - - - - - - -
PIBGAFCF_01411 8.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PIBGAFCF_01412 1.33e-199 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_01413 9.29e-207 - - - S - - - Conserved hypothetical protein 698
PIBGAFCF_01414 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
PIBGAFCF_01415 6.64e-185 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
PIBGAFCF_01416 2.37e-20 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PIBGAFCF_01418 1.08e-86 dinB - - S - - - DinB family
PIBGAFCF_01419 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PIBGAFCF_01420 5.82e-16 - - - - - - - -
PIBGAFCF_01421 2.04e-10 - - - - - - - -
PIBGAFCF_01422 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
PIBGAFCF_01423 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PIBGAFCF_01424 1.52e-164 yoaP - - K - - - YoaP-like
PIBGAFCF_01425 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
PIBGAFCF_01427 1.87e-53 - - - - - - - -
PIBGAFCF_01429 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
PIBGAFCF_01430 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_01431 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
PIBGAFCF_01432 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PIBGAFCF_01433 1.97e-119 yvgO - - - - - - -
PIBGAFCF_01435 0.0 yobO - - M - - - Pectate lyase superfamily protein
PIBGAFCF_01436 1.33e-43 - - - S - - - TM2 domain
PIBGAFCF_01437 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PIBGAFCF_01438 2.53e-162 yndL - - S - - - Replication protein
PIBGAFCF_01439 4.12e-10 - - - - - - - -
PIBGAFCF_01440 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
PIBGAFCF_01441 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
PIBGAFCF_01443 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIBGAFCF_01444 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PIBGAFCF_01445 4.8e-141 yneB - - L - - - resolvase
PIBGAFCF_01446 2.33e-43 ynzC - - S - - - UPF0291 protein
PIBGAFCF_01447 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PIBGAFCF_01448 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
PIBGAFCF_01449 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
PIBGAFCF_01450 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
PIBGAFCF_01451 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PIBGAFCF_01452 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
PIBGAFCF_01453 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
PIBGAFCF_01454 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
PIBGAFCF_01455 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
PIBGAFCF_01456 3.28e-26 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
PIBGAFCF_01457 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
PIBGAFCF_01458 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PIBGAFCF_01459 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PIBGAFCF_01461 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
PIBGAFCF_01462 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
PIBGAFCF_01463 5.95e-65 yneQ - - - - - - -
PIBGAFCF_01464 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
PIBGAFCF_01465 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIBGAFCF_01466 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PIBGAFCF_01467 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIBGAFCF_01468 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIBGAFCF_01469 2.21e-19 - - - - - - - -
PIBGAFCF_01470 2.04e-60 ynfC - - - - - - -
PIBGAFCF_01471 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PIBGAFCF_01472 1.56e-28 yndG - - S - - - DoxX-like family
PIBGAFCF_01473 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
PIBGAFCF_01474 0.0 yndJ - - S - - - YndJ-like protein
PIBGAFCF_01475 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
PIBGAFCF_01476 3.49e-282 - - - T - - - Histidine kinase
PIBGAFCF_01477 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
PIBGAFCF_01478 2.01e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
PIBGAFCF_01479 1.02e-289 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PIBGAFCF_01480 6.1e-34 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PIBGAFCF_01481 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01482 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01483 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01484 5.54e-193 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PIBGAFCF_01485 1.26e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PIBGAFCF_01486 5.28e-135 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PIBGAFCF_01487 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PIBGAFCF_01488 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PIBGAFCF_01489 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PIBGAFCF_01490 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PIBGAFCF_01491 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PIBGAFCF_01492 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PIBGAFCF_01493 2.75e-169 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PIBGAFCF_01494 1.02e-88 yngA - - S - - - membrane
PIBGAFCF_01495 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PIBGAFCF_01496 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
PIBGAFCF_01497 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PIBGAFCF_01498 1.79e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
PIBGAFCF_01499 3.73e-209 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
PIBGAFCF_01500 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
PIBGAFCF_01501 6.49e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PIBGAFCF_01502 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PIBGAFCF_01503 2.84e-263 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PIBGAFCF_01504 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
PIBGAFCF_01505 5.39e-82 yngL - - S - - - Protein of unknown function (DUF1360)
PIBGAFCF_01506 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
PIBGAFCF_01507 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01508 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01509 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PIBGAFCF_01510 1.56e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PIBGAFCF_01511 7.59e-305 yoeA - - V - - - MATE efflux family protein
PIBGAFCF_01512 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
PIBGAFCF_01514 7.69e-123 - - - L - - - Integrase
PIBGAFCF_01515 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
PIBGAFCF_01516 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PIBGAFCF_01517 6.45e-238 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
PIBGAFCF_01518 1.91e-66 - - - K - - - Helix-turn-helix domain
PIBGAFCF_01519 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIBGAFCF_01520 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PIBGAFCF_01521 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PIBGAFCF_01522 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_01523 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIBGAFCF_01524 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIBGAFCF_01525 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PIBGAFCF_01526 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_01527 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIBGAFCF_01528 6.92e-147 yoxB - - - - - - -
PIBGAFCF_01529 1.15e-54 ycgF - - E - - - Lysine exporter protein LysE YggA
PIBGAFCF_01530 6.64e-76 ycgF - - E - - - Lysine exporter protein LysE YggA
PIBGAFCF_01531 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PIBGAFCF_01532 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_01533 2.87e-89 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
PIBGAFCF_01534 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIBGAFCF_01535 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
PIBGAFCF_01536 1.72e-245 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_01537 1.06e-27 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_01538 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PIBGAFCF_01539 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PIBGAFCF_01540 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
PIBGAFCF_01541 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PIBGAFCF_01542 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PIBGAFCF_01543 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIBGAFCF_01544 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
PIBGAFCF_01545 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PIBGAFCF_01546 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PIBGAFCF_01547 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
PIBGAFCF_01548 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PIBGAFCF_01549 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PIBGAFCF_01550 9.85e-281 yciC - - S - - - GTPases (G3E family)
PIBGAFCF_01551 2.55e-221 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PIBGAFCF_01552 3.65e-94 yckC - - S - - - membrane
PIBGAFCF_01553 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
PIBGAFCF_01554 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_01555 7.34e-86 nin - - S - - - Competence protein J (ComJ)
PIBGAFCF_01556 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
PIBGAFCF_01557 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PIBGAFCF_01558 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
PIBGAFCF_01559 2.89e-84 hxlR - - K - - - transcriptional
PIBGAFCF_01562 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PIBGAFCF_01563 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIBGAFCF_01564 9.99e-39 yazB - - K - - - transcriptional
PIBGAFCF_01565 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PIBGAFCF_01566 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PIBGAFCF_01567 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PIBGAFCF_01568 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
PIBGAFCF_01569 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
PIBGAFCF_01570 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PIBGAFCF_01571 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PIBGAFCF_01572 1.22e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
PIBGAFCF_01573 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIBGAFCF_01574 6.69e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PIBGAFCF_01575 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIBGAFCF_01576 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PIBGAFCF_01577 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIBGAFCF_01578 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
PIBGAFCF_01579 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PIBGAFCF_01580 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
PIBGAFCF_01583 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PIBGAFCF_01584 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PIBGAFCF_01585 5.13e-129 yabQ - - S - - - spore cortex biosynthesis protein
PIBGAFCF_01586 5.47e-66 yabP - - S - - - Sporulation protein YabP
PIBGAFCF_01587 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PIBGAFCF_01588 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PIBGAFCF_01589 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_01590 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
PIBGAFCF_01591 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIBGAFCF_01592 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
PIBGAFCF_01593 3.37e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIBGAFCF_01594 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PIBGAFCF_01595 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIBGAFCF_01596 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIBGAFCF_01597 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PIBGAFCF_01598 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
PIBGAFCF_01599 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PIBGAFCF_01600 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PIBGAFCF_01601 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
PIBGAFCF_01602 5.32e-53 veg - - S - - - protein conserved in bacteria
PIBGAFCF_01603 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
PIBGAFCF_01604 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIBGAFCF_01605 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIBGAFCF_01606 3.55e-288 yabE - - T - - - protein conserved in bacteria
PIBGAFCF_01607 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
PIBGAFCF_01608 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIBGAFCF_01609 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
PIBGAFCF_01610 2.81e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIBGAFCF_01611 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PIBGAFCF_01612 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
PIBGAFCF_01613 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
PIBGAFCF_01614 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
PIBGAFCF_01615 5.75e-224 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PIBGAFCF_01616 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
PIBGAFCF_01617 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
PIBGAFCF_01618 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIBGAFCF_01619 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
PIBGAFCF_01620 3.65e-225 yaaN - - P - - - Belongs to the TelA family
PIBGAFCF_01621 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PIBGAFCF_01622 3.55e-39 csfB - - S - - - Inhibitor of sigma-G Gin
PIBGAFCF_01623 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_01624 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
PIBGAFCF_01625 1.14e-175 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
PIBGAFCF_01626 2.92e-314 - - - E - - - Aminotransferase class I and II
PIBGAFCF_01627 5.87e-155 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PIBGAFCF_01628 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
PIBGAFCF_01629 1.32e-167 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PIBGAFCF_01630 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PIBGAFCF_01631 8.12e-55 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PIBGAFCF_01632 8.22e-86 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PIBGAFCF_01633 2.91e-197 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
PIBGAFCF_01634 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PIBGAFCF_01635 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PIBGAFCF_01636 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
PIBGAFCF_01637 8.93e-96 yclD - - - - - - -
PIBGAFCF_01638 6.81e-300 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_01639 3.29e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIBGAFCF_01640 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
PIBGAFCF_01641 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
PIBGAFCF_01642 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIBGAFCF_01643 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIBGAFCF_01644 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIBGAFCF_01645 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIBGAFCF_01646 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIBGAFCF_01647 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PIBGAFCF_01649 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PIBGAFCF_01650 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PIBGAFCF_01651 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_01652 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
PIBGAFCF_01653 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PIBGAFCF_01654 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PIBGAFCF_01655 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
PIBGAFCF_01656 3.45e-53 yuxK - - S - - - protein conserved in bacteria
PIBGAFCF_01657 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
PIBGAFCF_01658 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
PIBGAFCF_01659 7.29e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
PIBGAFCF_01660 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
PIBGAFCF_01661 5e-278 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_01662 1.89e-276 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PIBGAFCF_01663 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
PIBGAFCF_01664 3.41e-192 yugF - - I - - - Hydrolase
PIBGAFCF_01665 1.07e-108 alaR - - K - - - Transcriptional regulator
PIBGAFCF_01666 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
PIBGAFCF_01667 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PIBGAFCF_01668 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
PIBGAFCF_01669 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
PIBGAFCF_01670 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
PIBGAFCF_01671 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PIBGAFCF_01673 4.57e-90 yugN - - S - - - YugN-like family
PIBGAFCF_01674 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
PIBGAFCF_01675 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
PIBGAFCF_01676 3.56e-22 - - - - - - - -
PIBGAFCF_01677 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
PIBGAFCF_01678 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PIBGAFCF_01679 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PIBGAFCF_01680 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PIBGAFCF_01681 1.82e-52 - - - - - - - -
PIBGAFCF_01682 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PIBGAFCF_01683 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PIBGAFCF_01684 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PIBGAFCF_01685 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PIBGAFCF_01686 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PIBGAFCF_01687 1.08e-15 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
PIBGAFCF_01688 2.09e-85 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
PIBGAFCF_01689 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PIBGAFCF_01690 2.73e-248 yubA - - S - - - transporter activity
PIBGAFCF_01691 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PIBGAFCF_01693 7.36e-20 - - - - - - - -
PIBGAFCF_01694 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
PIBGAFCF_01697 2.17e-57 yjcN - - - - - - -
PIBGAFCF_01698 2.36e-47 - - - G - - - Cupin
PIBGAFCF_01699 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PIBGAFCF_01700 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIBGAFCF_01701 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PIBGAFCF_01702 4.6e-119 yuaB - - - - - - -
PIBGAFCF_01703 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
PIBGAFCF_01704 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PIBGAFCF_01705 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PIBGAFCF_01706 1.21e-134 - - - S - - - MOSC domain
PIBGAFCF_01707 1.42e-102 yuaE - - S - - - DinB superfamily
PIBGAFCF_01708 1.48e-104 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
PIBGAFCF_01709 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
PIBGAFCF_01710 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
PIBGAFCF_01711 7.59e-196 yokA - - L - - - Recombinase
PIBGAFCF_01712 1.36e-111 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
PIBGAFCF_01713 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
PIBGAFCF_01714 1e-170 - - - V - - - HNH endonuclease
PIBGAFCF_01715 6.88e-20 - - - V - - - HNH endonuclease
PIBGAFCF_01716 1.12e-286 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PIBGAFCF_01717 3.18e-67 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PIBGAFCF_01719 3.77e-225 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PIBGAFCF_01720 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
PIBGAFCF_01721 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PIBGAFCF_01722 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PIBGAFCF_01723 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
PIBGAFCF_01724 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PIBGAFCF_01725 6.16e-263 xylR - - GK - - - ROK family
PIBGAFCF_01726 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PIBGAFCF_01727 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
PIBGAFCF_01728 1.54e-271 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PIBGAFCF_01729 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PIBGAFCF_01733 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PIBGAFCF_01734 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
PIBGAFCF_01735 3.09e-306 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PIBGAFCF_01736 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIBGAFCF_01737 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PIBGAFCF_01738 1.23e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_01739 3.03e-07 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_01740 2.21e-132 ymaB - - S - - - MutT family
PIBGAFCF_01741 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_01742 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_01743 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PIBGAFCF_01744 2.31e-29 ymzA - - - - - - -
PIBGAFCF_01745 1.87e-53 - - - - - - - -
PIBGAFCF_01746 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PIBGAFCF_01747 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIBGAFCF_01748 9.08e-72 ymaF - - S - - - YmaF family
PIBGAFCF_01750 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PIBGAFCF_01751 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PIBGAFCF_01752 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
PIBGAFCF_01753 3.08e-151 ymaC - - S - - - Replication protein
PIBGAFCF_01754 2.64e-07 - - - - - - - -
PIBGAFCF_01755 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
PIBGAFCF_01756 9.32e-81 ymzB - - - - - - -
PIBGAFCF_01757 3.52e-149 yoaK - - S - - - Membrane
PIBGAFCF_01758 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
PIBGAFCF_01759 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PIBGAFCF_01760 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
PIBGAFCF_01761 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PIBGAFCF_01762 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PIBGAFCF_01763 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PIBGAFCF_01764 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
PIBGAFCF_01765 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
PIBGAFCF_01766 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
PIBGAFCF_01767 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
PIBGAFCF_01768 9.98e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
PIBGAFCF_01769 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
PIBGAFCF_01770 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PIBGAFCF_01771 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
PIBGAFCF_01772 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PIBGAFCF_01773 3.58e-160 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
PIBGAFCF_01774 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIBGAFCF_01775 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIBGAFCF_01776 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
PIBGAFCF_01777 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PIBGAFCF_01778 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PIBGAFCF_01779 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PIBGAFCF_01780 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PIBGAFCF_01781 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
PIBGAFCF_01782 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
PIBGAFCF_01783 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PIBGAFCF_01784 4.31e-260 pbpX - - V - - - Beta-lactamase
PIBGAFCF_01785 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIBGAFCF_01786 2.57e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PIBGAFCF_01787 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIBGAFCF_01788 2.26e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
PIBGAFCF_01789 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
PIBGAFCF_01790 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
PIBGAFCF_01791 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PIBGAFCF_01792 2.09e-303 ymfH - - S - - - zinc protease
PIBGAFCF_01793 8.12e-300 albE - - S - - - Peptidase M16
PIBGAFCF_01794 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
PIBGAFCF_01795 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_01796 1.6e-289 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_01797 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_01798 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PIBGAFCF_01799 7.4e-41 - - - S - - - YlzJ-like protein
PIBGAFCF_01800 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
PIBGAFCF_01801 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIBGAFCF_01802 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIBGAFCF_01803 3.69e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PIBGAFCF_01804 8.84e-243 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIBGAFCF_01805 2.43e-48 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PIBGAFCF_01806 7.23e-99 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
PIBGAFCF_01807 6.24e-214 pre - - D - - - plasmid recombination enzyme
PIBGAFCF_01808 5.2e-108 - - - K - - - Transcriptional regulator
PIBGAFCF_01812 1.08e-224 - - - L - - - Replication protein
PIBGAFCF_01815 1.82e-17 - - - L ko:K06400 - ko00000 Recombinase
PIBGAFCF_01816 5.57e-159 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_01817 2.47e-274 - - - EGP - - - Transmembrane secretion effector
PIBGAFCF_01818 9.72e-08 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
PIBGAFCF_01820 1.97e-35 yqeD - - S - - - SNARE associated Golgi protein
PIBGAFCF_01821 1.33e-32 yqeD - - S - - - SNARE associated Golgi protein
PIBGAFCF_01822 3.16e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PIBGAFCF_01823 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
PIBGAFCF_01825 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PIBGAFCF_01826 1.87e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PIBGAFCF_01827 2.83e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIBGAFCF_01828 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
PIBGAFCF_01829 3.25e-137 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIBGAFCF_01830 3.25e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PIBGAFCF_01831 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIBGAFCF_01832 1.98e-177 yqeM - - Q - - - Methyltransferase
PIBGAFCF_01833 1.14e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIBGAFCF_01834 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PIBGAFCF_01835 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PIBGAFCF_01836 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PIBGAFCF_01837 6.09e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PIBGAFCF_01838 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PIBGAFCF_01839 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PIBGAFCF_01840 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PIBGAFCF_01841 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
PIBGAFCF_01842 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIBGAFCF_01843 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PIBGAFCF_01844 1.11e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIBGAFCF_01845 1.99e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIBGAFCF_01846 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PIBGAFCF_01847 6.71e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIBGAFCF_01848 1.27e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
PIBGAFCF_01849 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PIBGAFCF_01850 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
PIBGAFCF_01851 1.99e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PIBGAFCF_01852 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PIBGAFCF_01853 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
PIBGAFCF_01854 3.91e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
PIBGAFCF_01855 1.22e-186 yqfA - - S - - - UPF0365 protein
PIBGAFCF_01856 6.35e-49 yqfB - - - - - - -
PIBGAFCF_01857 3.57e-61 yqfC - - S - - - sporulation protein YqfC
PIBGAFCF_01858 3.96e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PIBGAFCF_01859 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
PIBGAFCF_01860 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
PIBGAFCF_01861 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIBGAFCF_01862 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PIBGAFCF_01863 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PIBGAFCF_01864 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIBGAFCF_01865 6e-24 - - - S - - - YqzL-like protein
PIBGAFCF_01866 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PIBGAFCF_01867 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PIBGAFCF_01868 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PIBGAFCF_01869 3.41e-144 ccpN - - K - - - CBS domain
PIBGAFCF_01870 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIBGAFCF_01871 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
PIBGAFCF_01872 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIBGAFCF_01873 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIBGAFCF_01874 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PIBGAFCF_01875 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PIBGAFCF_01876 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIBGAFCF_01877 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PIBGAFCF_01878 7.12e-57 yqfQ - - S - - - YqfQ-like protein
PIBGAFCF_01879 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIBGAFCF_01880 9.16e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PIBGAFCF_01881 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
PIBGAFCF_01882 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_01883 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
PIBGAFCF_01884 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
PIBGAFCF_01885 2.26e-78 yqfX - - S - - - membrane
PIBGAFCF_01886 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PIBGAFCF_01887 9.88e-58 yqfZ - - M ko:K06417 - ko00000 LysM domain
PIBGAFCF_01888 8.5e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
PIBGAFCF_01889 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
PIBGAFCF_01890 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PIBGAFCF_01891 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
PIBGAFCF_01892 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PIBGAFCF_01893 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PIBGAFCF_01894 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PIBGAFCF_01895 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PIBGAFCF_01896 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIBGAFCF_01897 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIBGAFCF_01898 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIBGAFCF_01899 3.42e-68 yqzD - - - - - - -
PIBGAFCF_01900 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PIBGAFCF_01901 1.16e-114 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIBGAFCF_01902 5.38e-11 yqgO - - - - - - -
PIBGAFCF_01903 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PIBGAFCF_01904 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
PIBGAFCF_01905 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PIBGAFCF_01906 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
PIBGAFCF_01907 1.57e-239 yqgU - - - - - - -
PIBGAFCF_01908 2.02e-63 dglA - - S - - - Thiamine-binding protein
PIBGAFCF_01909 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
PIBGAFCF_01910 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PIBGAFCF_01911 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
PIBGAFCF_01912 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PIBGAFCF_01914 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIBGAFCF_01915 7.43e-295 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PIBGAFCF_01916 1.34e-231 yqxL - - P - - - Mg2 transporter protein
PIBGAFCF_01917 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PIBGAFCF_01918 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
PIBGAFCF_01919 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PIBGAFCF_01920 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
PIBGAFCF_01921 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
PIBGAFCF_01922 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PIBGAFCF_01923 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
PIBGAFCF_01924 9.56e-35 yqzE - - S - - - YqzE-like protein
PIBGAFCF_01925 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
PIBGAFCF_01926 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
PIBGAFCF_01927 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
PIBGAFCF_01928 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
PIBGAFCF_01929 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
PIBGAFCF_01930 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
PIBGAFCF_01931 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
PIBGAFCF_01932 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PIBGAFCF_01933 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
PIBGAFCF_01934 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PIBGAFCF_01935 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PIBGAFCF_01936 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
PIBGAFCF_01937 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PIBGAFCF_01938 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PIBGAFCF_01939 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PIBGAFCF_01940 8.59e-80 yqhP - - - - - - -
PIBGAFCF_01941 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
PIBGAFCF_01942 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
PIBGAFCF_01943 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PIBGAFCF_01944 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIBGAFCF_01945 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
PIBGAFCF_01946 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
PIBGAFCF_01947 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
PIBGAFCF_01948 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
PIBGAFCF_01949 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
PIBGAFCF_01950 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
PIBGAFCF_01951 4.98e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
PIBGAFCF_01952 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
PIBGAFCF_01953 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
PIBGAFCF_01954 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIBGAFCF_01955 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PIBGAFCF_01956 5.53e-87 yqhY - - S - - - protein conserved in bacteria
PIBGAFCF_01957 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIBGAFCF_01958 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIBGAFCF_01959 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIBGAFCF_01960 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIBGAFCF_01961 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PIBGAFCF_01962 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIBGAFCF_01963 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
PIBGAFCF_01964 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PIBGAFCF_01965 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PIBGAFCF_01966 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
PIBGAFCF_01967 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PIBGAFCF_01969 7.14e-259 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIBGAFCF_01972 2.85e-266 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PIBGAFCF_01974 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
PIBGAFCF_01975 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
PIBGAFCF_01977 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
PIBGAFCF_01978 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PIBGAFCF_01979 9.92e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PIBGAFCF_01980 1.86e-185 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
PIBGAFCF_01981 1.94e-125 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PIBGAFCF_01982 9.44e-109 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PIBGAFCF_01983 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PIBGAFCF_01984 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
PIBGAFCF_01985 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PIBGAFCF_01986 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
PIBGAFCF_01987 0.0 bkdR - - KT - - - Transcriptional regulator
PIBGAFCF_01988 2.17e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
PIBGAFCF_01989 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PIBGAFCF_01990 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
PIBGAFCF_01991 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIBGAFCF_01992 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIBGAFCF_01993 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIBGAFCF_01994 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIBGAFCF_01995 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PIBGAFCF_01996 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
PIBGAFCF_01997 6.26e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PIBGAFCF_01998 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PIBGAFCF_01999 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PIBGAFCF_02000 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
PIBGAFCF_02001 3.99e-118 yqjB - - S - - - protein conserved in bacteria
PIBGAFCF_02003 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
PIBGAFCF_02004 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PIBGAFCF_02005 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
PIBGAFCF_02006 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIBGAFCF_02007 1.36e-36 yqzJ - - - - - - -
PIBGAFCF_02008 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIBGAFCF_02009 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIBGAFCF_02010 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIBGAFCF_02011 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIBGAFCF_02012 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PIBGAFCF_02013 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PIBGAFCF_02014 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PIBGAFCF_02015 2.42e-61 - - - S - - - GlpM protein
PIBGAFCF_02016 9.08e-202 - - - K - - - LysR substrate binding domain
PIBGAFCF_02017 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIBGAFCF_02018 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PIBGAFCF_02019 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_02020 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PIBGAFCF_02021 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PIBGAFCF_02023 5.73e-206 yueF - - S - - - transporter activity
PIBGAFCF_02025 7.27e-73 - - - S - - - YolD-like protein
PIBGAFCF_02026 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIBGAFCF_02027 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
PIBGAFCF_02028 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
PIBGAFCF_02029 4.54e-211 yqkA - - K - - - GrpB protein
PIBGAFCF_02030 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
PIBGAFCF_02031 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
PIBGAFCF_02032 2.61e-213 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PIBGAFCF_02033 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
PIBGAFCF_02034 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PIBGAFCF_02035 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
PIBGAFCF_02036 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PIBGAFCF_02037 1.43e-271 yqxK - - L - - - DNA helicase
PIBGAFCF_02038 2.32e-75 ansR - - K - - - Transcriptional regulator
PIBGAFCF_02039 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
PIBGAFCF_02040 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
PIBGAFCF_02041 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PIBGAFCF_02042 1.87e-306 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PIBGAFCF_02043 2.91e-32 - - - - - - - -
PIBGAFCF_02044 2.87e-43 yqkK - - - - - - -
PIBGAFCF_02045 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PIBGAFCF_02046 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PIBGAFCF_02047 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
PIBGAFCF_02048 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
PIBGAFCF_02049 4.39e-288 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIBGAFCF_02050 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PIBGAFCF_02051 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PIBGAFCF_02052 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
PIBGAFCF_02053 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PIBGAFCF_02054 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_02055 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
PIBGAFCF_02056 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
PIBGAFCF_02057 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PIBGAFCF_02058 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PIBGAFCF_02059 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
PIBGAFCF_02060 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
PIBGAFCF_02061 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
PIBGAFCF_02062 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIBGAFCF_02063 3.35e-194 ypuA - - S - - - Secreted protein
PIBGAFCF_02064 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIBGAFCF_02065 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
PIBGAFCF_02066 2.37e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PIBGAFCF_02067 7.86e-68 ypuD - - - - - - -
PIBGAFCF_02068 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PIBGAFCF_02069 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PIBGAFCF_02070 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PIBGAFCF_02071 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PIBGAFCF_02072 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIBGAFCF_02073 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
PIBGAFCF_02075 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIBGAFCF_02076 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIBGAFCF_02077 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
PIBGAFCF_02078 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PIBGAFCF_02079 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
PIBGAFCF_02080 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
PIBGAFCF_02081 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PIBGAFCF_02082 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PIBGAFCF_02083 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
PIBGAFCF_02084 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PIBGAFCF_02085 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_02086 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_02087 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_02088 6.63e-216 rsiX - - - - - - -
PIBGAFCF_02089 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIBGAFCF_02090 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIBGAFCF_02091 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
PIBGAFCF_02092 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
PIBGAFCF_02093 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PIBGAFCF_02094 2.24e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
PIBGAFCF_02095 8.85e-110 ypbE - - M - - - Lysin motif
PIBGAFCF_02096 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
PIBGAFCF_02097 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PIBGAFCF_02098 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PIBGAFCF_02099 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PIBGAFCF_02100 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
PIBGAFCF_02101 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
PIBGAFCF_02102 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
PIBGAFCF_02103 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
PIBGAFCF_02104 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
PIBGAFCF_02105 6.47e-17 - - - S - - - Family of unknown function (DUF5359)
PIBGAFCF_02106 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PIBGAFCF_02107 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PIBGAFCF_02108 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIBGAFCF_02109 1.32e-12 - - - S - - - YpzI-like protein
PIBGAFCF_02110 1.29e-128 yphA - - - - - - -
PIBGAFCF_02111 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PIBGAFCF_02112 3.72e-239 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PIBGAFCF_02113 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
PIBGAFCF_02114 2.47e-166 yphF - - - - - - -
PIBGAFCF_02116 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PIBGAFCF_02117 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIBGAFCF_02118 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PIBGAFCF_02119 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PIBGAFCF_02120 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PIBGAFCF_02121 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PIBGAFCF_02122 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PIBGAFCF_02123 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PIBGAFCF_02124 2.01e-33 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PIBGAFCF_02125 4.44e-131 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PIBGAFCF_02126 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PIBGAFCF_02127 1.14e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PIBGAFCF_02128 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PIBGAFCF_02129 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PIBGAFCF_02130 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PIBGAFCF_02131 1.15e-158 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PIBGAFCF_02132 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PIBGAFCF_02133 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PIBGAFCF_02134 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PIBGAFCF_02135 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PIBGAFCF_02136 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PIBGAFCF_02137 3.79e-290 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PIBGAFCF_02138 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
PIBGAFCF_02139 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
PIBGAFCF_02140 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
PIBGAFCF_02141 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
PIBGAFCF_02142 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
PIBGAFCF_02143 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
PIBGAFCF_02144 6.12e-126 ypjA - - S - - - membrane
PIBGAFCF_02145 1.09e-177 ypjB - - S - - - sporulation protein
PIBGAFCF_02146 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PIBGAFCF_02147 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_02148 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
PIBGAFCF_02149 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIBGAFCF_02150 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
PIBGAFCF_02151 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
PIBGAFCF_02152 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
PIBGAFCF_02153 1.53e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIBGAFCF_02154 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIBGAFCF_02155 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PIBGAFCF_02156 1.38e-193 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PIBGAFCF_02157 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PIBGAFCF_02158 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PIBGAFCF_02159 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
PIBGAFCF_02160 2.74e-95 ypmB - - S - - - protein conserved in bacteria
PIBGAFCF_02161 1.1e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PIBGAFCF_02162 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
PIBGAFCF_02163 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
PIBGAFCF_02164 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIBGAFCF_02165 4.6e-113 ypoC - - - - - - -
PIBGAFCF_02166 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PIBGAFCF_02167 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIBGAFCF_02168 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
PIBGAFCF_02173 5.58e-60 yppG - - S - - - YppG-like protein
PIBGAFCF_02174 1.56e-78 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PIBGAFCF_02175 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
PIBGAFCF_02176 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PIBGAFCF_02177 9.55e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
PIBGAFCF_02179 8.12e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
PIBGAFCF_02180 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
PIBGAFCF_02181 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIBGAFCF_02182 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PIBGAFCF_02183 8.55e-77 yqgA - - - - - - -
PIBGAFCF_02184 6.91e-31 - - - S - - - YpzG-like protein
PIBGAFCF_02186 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
PIBGAFCF_02187 1.95e-186 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PIBGAFCF_02188 1.46e-159 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PIBGAFCF_02189 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIBGAFCF_02190 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
PIBGAFCF_02191 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
PIBGAFCF_02192 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
PIBGAFCF_02193 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
PIBGAFCF_02194 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PIBGAFCF_02195 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
PIBGAFCF_02196 0.0 ypbR - - S - - - Dynamin family
PIBGAFCF_02197 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
PIBGAFCF_02198 5.97e-11 - - - - - - - -
PIBGAFCF_02199 2.07e-204 ypcP - - L - - - 5'3' exonuclease
PIBGAFCF_02201 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
PIBGAFCF_02202 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PIBGAFCF_02203 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
PIBGAFCF_02204 6.37e-38 ypeQ - - S - - - Zinc-finger
PIBGAFCF_02205 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
PIBGAFCF_02206 4.27e-16 degR - - - - - - -
PIBGAFCF_02207 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PIBGAFCF_02208 2.89e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PIBGAFCF_02209 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PIBGAFCF_02211 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PIBGAFCF_02212 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
PIBGAFCF_02213 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
PIBGAFCF_02214 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PIBGAFCF_02215 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
PIBGAFCF_02216 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
PIBGAFCF_02217 1.41e-142 ypjP - - S - - - YpjP-like protein
PIBGAFCF_02218 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIBGAFCF_02219 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIBGAFCF_02220 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PIBGAFCF_02221 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PIBGAFCF_02222 1.54e-207 yplP - - K - - - Transcriptional regulator
PIBGAFCF_02223 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PIBGAFCF_02224 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
PIBGAFCF_02225 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PIBGAFCF_02226 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
PIBGAFCF_02227 2.45e-122 ypmS - - S - - - protein conserved in bacteria
PIBGAFCF_02228 1.42e-88 ypoP - - K - - - transcriptional
PIBGAFCF_02229 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIBGAFCF_02230 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PIBGAFCF_02231 4.5e-155 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PIBGAFCF_02232 9.6e-268 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
PIBGAFCF_02233 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
PIBGAFCF_02234 1.08e-81 cgeA - - - ko:K06319 - ko00000 -
PIBGAFCF_02235 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
PIBGAFCF_02236 1.17e-286 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
PIBGAFCF_02237 1.13e-175 yiiD - - K ko:K06323 - ko00000 acetyltransferase
PIBGAFCF_02239 3.54e-83 - - - L - - - Bacterial transcription activator, effector binding domain
PIBGAFCF_02241 2.4e-296 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIBGAFCF_02242 5.2e-156 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PIBGAFCF_02243 3.36e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PIBGAFCF_02244 4.03e-315 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
PIBGAFCF_02245 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
PIBGAFCF_02246 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PIBGAFCF_02247 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
PIBGAFCF_02248 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
PIBGAFCF_02249 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_02250 1.18e-155 yodN - - - - - - -
PIBGAFCF_02252 1.97e-33 yozD - - S - - - YozD-like protein
PIBGAFCF_02253 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PIBGAFCF_02254 1.16e-72 yodL - - S - - - YodL-like
PIBGAFCF_02256 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PIBGAFCF_02257 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PIBGAFCF_02258 2.3e-30 yodI - - - - - - -
PIBGAFCF_02259 1.43e-155 yodH - - Q - - - Methyltransferase
PIBGAFCF_02260 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PIBGAFCF_02261 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_02262 3.26e-270 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_02263 1.12e-33 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_02264 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
PIBGAFCF_02265 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIBGAFCF_02266 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
PIBGAFCF_02267 1.82e-108 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PIBGAFCF_02268 8.05e-58 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PIBGAFCF_02269 1.35e-137 yahD - - S ko:K06999 - ko00000 Carboxylesterase
PIBGAFCF_02270 6.14e-135 yodC - - C - - - nitroreductase
PIBGAFCF_02271 1.93e-69 yodB - - K - - - transcriptional
PIBGAFCF_02272 9.37e-83 iolK - - S - - - tautomerase
PIBGAFCF_02274 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
PIBGAFCF_02275 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
PIBGAFCF_02276 3.66e-31 - - - - - - - -
PIBGAFCF_02277 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
PIBGAFCF_02278 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
PIBGAFCF_02279 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIBGAFCF_02280 3.54e-296 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PIBGAFCF_02281 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIBGAFCF_02282 6.89e-278 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
PIBGAFCF_02283 1.26e-199 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PIBGAFCF_02284 1.31e-135 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PIBGAFCF_02285 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
PIBGAFCF_02286 0.0 yojO - - P - - - Von Willebrand factor
PIBGAFCF_02287 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PIBGAFCF_02288 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PIBGAFCF_02289 4.3e-56 - - - S - - - Metallo-beta-lactamase superfamily
PIBGAFCF_02290 3.33e-86 - - - S - - - Metallo-beta-lactamase superfamily
PIBGAFCF_02291 3.02e-209 yocS - - S ko:K03453 - ko00000 -transporter
PIBGAFCF_02292 2.2e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PIBGAFCF_02293 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
PIBGAFCF_02294 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
PIBGAFCF_02295 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PIBGAFCF_02296 4.69e-43 yozC - - - - - - -
PIBGAFCF_02298 5.32e-75 yozO - - S - - - Bacterial PH domain
PIBGAFCF_02299 1.83e-49 yocN - - - - - - -
PIBGAFCF_02300 8.77e-41 yozN - - - - - - -
PIBGAFCF_02301 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PIBGAFCF_02302 1.16e-11 yocN - - - - - - -
PIBGAFCF_02304 7.44e-78 yocK - - T - - - general stress protein
PIBGAFCF_02305 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIBGAFCF_02307 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PIBGAFCF_02308 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
PIBGAFCF_02310 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
PIBGAFCF_02311 3.49e-118 yocC - - - - - - -
PIBGAFCF_02312 9.94e-172 - - - J - - - Protein required for attachment to host cells
PIBGAFCF_02313 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
PIBGAFCF_02314 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PIBGAFCF_02315 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
PIBGAFCF_02316 1.29e-117 yobW - - - - - - -
PIBGAFCF_02317 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PIBGAFCF_02318 1.44e-110 yobS - - K - - - Transcriptional regulator
PIBGAFCF_02319 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
PIBGAFCF_02320 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
PIBGAFCF_02323 1.52e-38 - - - - - - - -
PIBGAFCF_02324 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_02326 6.3e-36 yoaF - - - - - - -
PIBGAFCF_02327 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIBGAFCF_02328 2.4e-237 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIBGAFCF_02329 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PIBGAFCF_02330 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PIBGAFCF_02331 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
PIBGAFCF_02332 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PIBGAFCF_02333 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PIBGAFCF_02334 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIBGAFCF_02335 1.22e-247 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PIBGAFCF_02336 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
PIBGAFCF_02337 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PIBGAFCF_02338 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PIBGAFCF_02339 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIBGAFCF_02340 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PIBGAFCF_02341 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PIBGAFCF_02342 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIBGAFCF_02343 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIBGAFCF_02344 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PIBGAFCF_02345 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PIBGAFCF_02346 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIBGAFCF_02347 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PIBGAFCF_02348 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIBGAFCF_02349 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIBGAFCF_02350 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIBGAFCF_02351 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIBGAFCF_02352 4.2e-139 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PIBGAFCF_02353 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIBGAFCF_02354 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIBGAFCF_02355 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
PIBGAFCF_02356 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIBGAFCF_02357 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIBGAFCF_02358 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIBGAFCF_02359 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIBGAFCF_02360 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
PIBGAFCF_02361 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PIBGAFCF_02362 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIBGAFCF_02363 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PIBGAFCF_02364 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIBGAFCF_02365 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIBGAFCF_02366 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIBGAFCF_02367 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIBGAFCF_02368 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIBGAFCF_02369 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIBGAFCF_02370 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PIBGAFCF_02371 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIBGAFCF_02372 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIBGAFCF_02373 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIBGAFCF_02374 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIBGAFCF_02375 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIBGAFCF_02376 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIBGAFCF_02377 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIBGAFCF_02378 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIBGAFCF_02379 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIBGAFCF_02380 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PIBGAFCF_02381 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PIBGAFCF_02382 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIBGAFCF_02383 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIBGAFCF_02384 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PIBGAFCF_02385 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIBGAFCF_02386 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PIBGAFCF_02387 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIBGAFCF_02388 2.67e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIBGAFCF_02389 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIBGAFCF_02390 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PIBGAFCF_02391 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIBGAFCF_02392 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIBGAFCF_02393 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIBGAFCF_02394 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIBGAFCF_02395 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIBGAFCF_02396 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PIBGAFCF_02397 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
PIBGAFCF_02399 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
PIBGAFCF_02400 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_02401 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PIBGAFCF_02402 1.95e-102 gerD - - - ko:K06294 - ko00000 -
PIBGAFCF_02403 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
PIBGAFCF_02404 4.44e-174 pdaB - - G - - - Polysaccharide deacetylase
PIBGAFCF_02427 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
PIBGAFCF_02428 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
PIBGAFCF_02429 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PIBGAFCF_02430 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PIBGAFCF_02431 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PIBGAFCF_02432 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PIBGAFCF_02433 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PIBGAFCF_02434 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PIBGAFCF_02435 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
PIBGAFCF_02436 9.63e-230 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PIBGAFCF_02437 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PIBGAFCF_02438 1.89e-53 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PIBGAFCF_02439 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PIBGAFCF_02440 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
PIBGAFCF_02441 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIBGAFCF_02442 1.66e-96 ytkA - - S - - - YtkA-like
PIBGAFCF_02444 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PIBGAFCF_02445 1.67e-77 ytkC - - S - - - Bacteriophage holin family
PIBGAFCF_02446 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PIBGAFCF_02447 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PIBGAFCF_02448 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PIBGAFCF_02449 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PIBGAFCF_02450 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PIBGAFCF_02451 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
PIBGAFCF_02452 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PIBGAFCF_02453 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIBGAFCF_02454 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PIBGAFCF_02455 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_02456 7.46e-80 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PIBGAFCF_02457 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
PIBGAFCF_02458 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
PIBGAFCF_02460 4.07e-133 ytqB - - J - - - Putative rRNA methylase
PIBGAFCF_02461 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
PIBGAFCF_02462 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
PIBGAFCF_02464 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
PIBGAFCF_02465 6.13e-200 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_02466 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PIBGAFCF_02467 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PIBGAFCF_02468 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PIBGAFCF_02469 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_02470 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PIBGAFCF_02471 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_02472 2.32e-216 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
PIBGAFCF_02473 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_02474 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
PIBGAFCF_02475 4.62e-130 ywaF - - S - - - Integral membrane protein
PIBGAFCF_02476 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
PIBGAFCF_02477 7.29e-172 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PIBGAFCF_02478 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
PIBGAFCF_02479 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PIBGAFCF_02480 8.6e-69 ytwF - - P - - - Sulfurtransferase
PIBGAFCF_02481 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
PIBGAFCF_02482 2.49e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PIBGAFCF_02483 1.37e-182 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PIBGAFCF_02484 6.99e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PIBGAFCF_02485 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PIBGAFCF_02486 1.62e-231 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_02487 3.57e-35 yteV - - S - - - Sporulation protein Cse60
PIBGAFCF_02488 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PIBGAFCF_02489 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
PIBGAFCF_02490 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_02491 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PIBGAFCF_02492 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
PIBGAFCF_02493 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PIBGAFCF_02494 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PIBGAFCF_02495 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
PIBGAFCF_02496 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
PIBGAFCF_02497 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PIBGAFCF_02498 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PIBGAFCF_02499 2.86e-198 ytlQ - - - - - - -
PIBGAFCF_02500 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PIBGAFCF_02501 3.42e-198 ytmP - - M - - - Phosphotransferase
PIBGAFCF_02502 4.54e-59 ytzH - - S - - - YtzH-like protein
PIBGAFCF_02503 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIBGAFCF_02504 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PIBGAFCF_02505 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PIBGAFCF_02506 9.96e-69 ytzB - - S - - - small secreted protein
PIBGAFCF_02507 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PIBGAFCF_02508 5.33e-98 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PIBGAFCF_02509 9.1e-75 ytpP - - CO - - - Thioredoxin
PIBGAFCF_02510 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
PIBGAFCF_02511 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIBGAFCF_02512 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PIBGAFCF_02513 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PIBGAFCF_02514 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIBGAFCF_02515 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
PIBGAFCF_02516 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
PIBGAFCF_02517 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PIBGAFCF_02518 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PIBGAFCF_02519 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PIBGAFCF_02520 1.87e-127 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PIBGAFCF_02521 1.4e-283 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
PIBGAFCF_02522 6.01e-134 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PIBGAFCF_02523 3.32e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PIBGAFCF_02524 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PIBGAFCF_02525 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIBGAFCF_02526 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
PIBGAFCF_02527 7.21e-154 ygaZ - - E - - - AzlC protein
PIBGAFCF_02528 1.06e-188 - - - K - - - Transcriptional regulator
PIBGAFCF_02529 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIBGAFCF_02530 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
PIBGAFCF_02532 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PIBGAFCF_02535 2.12e-273 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PIBGAFCF_02536 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIBGAFCF_02537 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
PIBGAFCF_02538 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PIBGAFCF_02539 2.22e-137 yttP - - K - - - Transcriptional regulator
PIBGAFCF_02540 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PIBGAFCF_02541 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIBGAFCF_02542 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PIBGAFCF_02543 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PIBGAFCF_02544 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIBGAFCF_02545 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
PIBGAFCF_02546 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PIBGAFCF_02547 0.0 ytcJ - - S - - - amidohydrolase
PIBGAFCF_02548 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIBGAFCF_02549 7.4e-93 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PIBGAFCF_02550 2.17e-108 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PIBGAFCF_02551 1.31e-103 yteJ - - S - - - RDD family
PIBGAFCF_02552 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
PIBGAFCF_02553 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
PIBGAFCF_02554 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIBGAFCF_02555 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PIBGAFCF_02556 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIBGAFCF_02557 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
PIBGAFCF_02558 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PIBGAFCF_02559 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PIBGAFCF_02561 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_02562 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
PIBGAFCF_02563 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
PIBGAFCF_02564 3.44e-60 ytpI - - S - - - YtpI-like protein
PIBGAFCF_02565 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
PIBGAFCF_02566 1.17e-30 - - - - - - - -
PIBGAFCF_02567 3.08e-113 ytrI - - - - - - -
PIBGAFCF_02568 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
PIBGAFCF_02569 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PIBGAFCF_02570 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PIBGAFCF_02571 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIBGAFCF_02572 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PIBGAFCF_02573 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIBGAFCF_02574 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PIBGAFCF_02575 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
PIBGAFCF_02576 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
PIBGAFCF_02577 1.14e-95 ytwI - - S - - - membrane
PIBGAFCF_02578 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PIBGAFCF_02579 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
PIBGAFCF_02580 2.1e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
PIBGAFCF_02581 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_02582 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
PIBGAFCF_02583 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIBGAFCF_02584 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIBGAFCF_02585 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
PIBGAFCF_02586 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIBGAFCF_02587 4.68e-198 ytbE - - S - - - reductase
PIBGAFCF_02588 3.31e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PIBGAFCF_02589 7.74e-86 ytcD - - K - - - Transcriptional regulator
PIBGAFCF_02590 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIBGAFCF_02591 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PIBGAFCF_02592 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIBGAFCF_02593 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
PIBGAFCF_02594 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PIBGAFCF_02595 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
PIBGAFCF_02596 6.12e-192 ytxC - - S - - - YtxC-like family
PIBGAFCF_02597 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIBGAFCF_02598 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
PIBGAFCF_02599 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_02600 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PIBGAFCF_02601 3.71e-65 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
PIBGAFCF_02602 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PIBGAFCF_02603 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIBGAFCF_02604 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PIBGAFCF_02605 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIBGAFCF_02606 5.91e-51 ysdA - - S - - - Membrane
PIBGAFCF_02607 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
PIBGAFCF_02608 6.18e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
PIBGAFCF_02609 6.16e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PIBGAFCF_02610 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PIBGAFCF_02611 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
PIBGAFCF_02612 1.4e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PIBGAFCF_02613 1.56e-174 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PIBGAFCF_02614 6.32e-05 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PIBGAFCF_02615 4.26e-234 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PIBGAFCF_02616 8.03e-314 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PIBGAFCF_02617 9.46e-210 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
PIBGAFCF_02618 2.11e-78 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
PIBGAFCF_02619 3.5e-69 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PIBGAFCF_02621 1.9e-09 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PIBGAFCF_02623 1.1e-14 - - - - - - - -
PIBGAFCF_02624 1.67e-15 - - - S - - - Protein of unknown function (DUF2815)
PIBGAFCF_02625 0.0 - - - L - - - Virulence-associated protein E
PIBGAFCF_02626 8.06e-27 - - - S - - - VRR_NUC
PIBGAFCF_02627 3.74e-288 - - - KL - - - SNF2 family N-terminal domain
PIBGAFCF_02628 4.27e-64 - - - - - - - -
PIBGAFCF_02630 2.38e-74 - - - L - - - Terminase, small subunit
PIBGAFCF_02631 6.45e-182 terL - - S - - - Terminase
PIBGAFCF_02633 8.49e-220 - - - S - - - portal protein
PIBGAFCF_02634 1.69e-95 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
PIBGAFCF_02635 2.4e-167 - - - S - - - capsid protein
PIBGAFCF_02636 5.73e-32 - - - - - - - -
PIBGAFCF_02637 5.7e-11 - - - S - - - Phage gp6-like head-tail connector protein
PIBGAFCF_02638 1.05e-40 - - - S - - - Phage head-tail joining protein
PIBGAFCF_02639 5.13e-43 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PIBGAFCF_02641 8.06e-43 - - - S - - - Phage tail tube protein
PIBGAFCF_02643 0.0 - - - D - - - Phage tail tape measure protein
PIBGAFCF_02644 6.57e-149 - - - S - - - Phage tail protein
PIBGAFCF_02645 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PIBGAFCF_02646 0.0 - - - M - - - Pectate lyase superfamily protein
PIBGAFCF_02647 6.89e-211 - - - S - - - Domain of unknown function (DUF2479)
PIBGAFCF_02650 2.25e-76 - - - S - - - Pfam:Phage_holin_4_1
PIBGAFCF_02651 5.17e-88 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_02653 3.22e-63 - - - - - - - -
PIBGAFCF_02654 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PIBGAFCF_02655 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
PIBGAFCF_02656 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
PIBGAFCF_02657 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
PIBGAFCF_02658 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
PIBGAFCF_02662 1.34e-95 - - - - - - - -
PIBGAFCF_02664 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
PIBGAFCF_02665 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PIBGAFCF_02666 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PIBGAFCF_02667 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PIBGAFCF_02668 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PIBGAFCF_02669 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
PIBGAFCF_02670 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PIBGAFCF_02671 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_02672 3.33e-209 bsn - - L - - - Ribonuclease
PIBGAFCF_02673 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PIBGAFCF_02674 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PIBGAFCF_02675 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_02676 6.3e-86 - - - - - - - -
PIBGAFCF_02677 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
PIBGAFCF_02678 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PIBGAFCF_02679 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
PIBGAFCF_02680 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
PIBGAFCF_02681 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
PIBGAFCF_02682 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PIBGAFCF_02683 2.12e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
PIBGAFCF_02684 1.6e-290 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PIBGAFCF_02685 8.24e-224 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PIBGAFCF_02686 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PIBGAFCF_02687 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_02688 4.67e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PIBGAFCF_02689 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PIBGAFCF_02690 1.14e-276 ywfA - - EGP - - - -transporter
PIBGAFCF_02691 9.06e-238 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PIBGAFCF_02692 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PIBGAFCF_02693 0.0 rocB - - E - - - arginine degradation protein
PIBGAFCF_02694 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PIBGAFCF_02695 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PIBGAFCF_02696 4.02e-80 - - - - - - - -
PIBGAFCF_02697 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
PIBGAFCF_02698 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIBGAFCF_02699 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIBGAFCF_02700 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PIBGAFCF_02701 9.02e-214 spsG - - M - - - Spore Coat
PIBGAFCF_02702 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
PIBGAFCF_02703 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
PIBGAFCF_02704 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
PIBGAFCF_02705 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PIBGAFCF_02706 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
PIBGAFCF_02707 4.13e-180 spsA - - M - - - Spore Coat
PIBGAFCF_02708 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PIBGAFCF_02709 4.39e-76 ywdK - - S - - - small membrane protein
PIBGAFCF_02710 3.47e-287 ywdJ - - F - - - Xanthine uracil
PIBGAFCF_02711 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
PIBGAFCF_02712 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIBGAFCF_02713 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
PIBGAFCF_02715 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PIBGAFCF_02716 6.09e-27 ywdA - - - - - - -
PIBGAFCF_02717 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PIBGAFCF_02718 7.23e-316 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02719 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PIBGAFCF_02721 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PIBGAFCF_02722 1.83e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_02723 1.26e-150 - - - K - - - WYL domain
PIBGAFCF_02724 8.59e-162 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_02725 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
PIBGAFCF_02726 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
PIBGAFCF_02727 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
PIBGAFCF_02728 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PIBGAFCF_02729 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
PIBGAFCF_02730 1.5e-41 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
PIBGAFCF_02731 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PIBGAFCF_02732 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PIBGAFCF_02733 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PIBGAFCF_02734 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PIBGAFCF_02735 5.74e-48 ydaS - - S - - - membrane
PIBGAFCF_02736 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PIBGAFCF_02737 4.36e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIBGAFCF_02738 7.8e-78 gtcA - - S - - - GtrA-like protein
PIBGAFCF_02739 1.41e-124 - - - K - - - Bacterial regulatory proteins, tetR family
PIBGAFCF_02741 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
PIBGAFCF_02742 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
PIBGAFCF_02743 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PIBGAFCF_02744 2.81e-296 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
PIBGAFCF_02745 5.54e-189 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
PIBGAFCF_02746 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
PIBGAFCF_02747 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PIBGAFCF_02748 9.98e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PIBGAFCF_02749 2.29e-200 ywbI - - K - - - Transcriptional regulator
PIBGAFCF_02750 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PIBGAFCF_02751 6.2e-142 ywbG - - M - - - effector of murein hydrolase
PIBGAFCF_02752 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
PIBGAFCF_02753 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
PIBGAFCF_02754 3.45e-80 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PIBGAFCF_02755 8.69e-31 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PIBGAFCF_02756 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PIBGAFCF_02757 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
PIBGAFCF_02758 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIBGAFCF_02759 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PIBGAFCF_02760 2.87e-205 gspA - - M - - - General stress
PIBGAFCF_02762 1.13e-66 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PIBGAFCF_02763 4.3e-67 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PIBGAFCF_02764 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PIBGAFCF_02765 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
PIBGAFCF_02766 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_02767 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
PIBGAFCF_02768 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_02769 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIBGAFCF_02770 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PIBGAFCF_02771 4.7e-316 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PIBGAFCF_02772 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02773 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIBGAFCF_02774 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
PIBGAFCF_02775 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PIBGAFCF_02776 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PIBGAFCF_02777 1.5e-216 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_02778 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_02779 4.01e-32 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PIBGAFCF_02780 9.31e-159 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PIBGAFCF_02781 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
PIBGAFCF_02782 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PIBGAFCF_02783 3.25e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02784 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02785 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIBGAFCF_02786 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_02787 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
PIBGAFCF_02788 5.01e-226 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PIBGAFCF_02789 2.24e-237 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PIBGAFCF_02790 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PIBGAFCF_02791 1.26e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PIBGAFCF_02792 2.06e-313 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
PIBGAFCF_02793 8.69e-192 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIBGAFCF_02794 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
PIBGAFCF_02795 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
PIBGAFCF_02796 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
PIBGAFCF_02797 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PIBGAFCF_02798 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
PIBGAFCF_02799 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
PIBGAFCF_02800 3.56e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PIBGAFCF_02801 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
PIBGAFCF_02802 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIBGAFCF_02804 2.34e-114 yxkC - - S - - - Domain of unknown function (DUF4352)
PIBGAFCF_02805 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PIBGAFCF_02806 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PIBGAFCF_02809 3.81e-105 yxjI - - S - - - LURP-one-related
PIBGAFCF_02810 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PIBGAFCF_02811 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
PIBGAFCF_02812 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIBGAFCF_02813 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
PIBGAFCF_02814 3.23e-60 yxiS - - - - - - -
PIBGAFCF_02815 3.81e-212 - - - L - - - DNA synthesis involved in DNA repair
PIBGAFCF_02816 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PIBGAFCF_02817 6.39e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PIBGAFCF_02818 9.73e-176 bglS - - M - - - licheninase activity
PIBGAFCF_02819 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PIBGAFCF_02820 1.59e-276 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
PIBGAFCF_02821 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PIBGAFCF_02823 9.75e-27 - - - - - - - -
PIBGAFCF_02825 9.77e-141 - - - - - - - -
PIBGAFCF_02826 4.23e-103 - - - - - - - -
PIBGAFCF_02827 2.91e-85 yxiG - - - - - - -
PIBGAFCF_02828 9.79e-75 yxxG - - - - - - -
PIBGAFCF_02830 4.8e-251 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PIBGAFCF_02831 7.42e-202 yxxF - - EG - - - EamA-like transporter family
PIBGAFCF_02832 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
PIBGAFCF_02833 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PIBGAFCF_02834 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02835 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PIBGAFCF_02836 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
PIBGAFCF_02837 4.99e-105 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PIBGAFCF_02839 0.0 - - - L - - - Z1 domain
PIBGAFCF_02840 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
PIBGAFCF_02841 8.8e-242 - - - S - - - AIPR protein
PIBGAFCF_02842 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PIBGAFCF_02843 6.75e-101 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PIBGAFCF_02844 2.08e-68 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PIBGAFCF_02845 2.19e-237 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
PIBGAFCF_02846 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PIBGAFCF_02847 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
PIBGAFCF_02848 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PIBGAFCF_02849 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PIBGAFCF_02850 5.23e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
PIBGAFCF_02851 1.35e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIBGAFCF_02852 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIBGAFCF_02853 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PIBGAFCF_02854 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
PIBGAFCF_02857 9.45e-26 yxeE - - - - - - -
PIBGAFCF_02859 9.67e-33 yxeD - - - - - - -
PIBGAFCF_02860 4.86e-47 - - - - - - - -
PIBGAFCF_02861 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PIBGAFCF_02862 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
PIBGAFCF_02863 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PIBGAFCF_02864 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_02865 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_02866 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_02867 3.58e-54 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PIBGAFCF_02868 2.52e-53 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PIBGAFCF_02869 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
PIBGAFCF_02870 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PIBGAFCF_02871 2.76e-289 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
PIBGAFCF_02872 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PIBGAFCF_02873 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PIBGAFCF_02874 8.2e-57 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PIBGAFCF_02875 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PIBGAFCF_02876 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIBGAFCF_02877 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PIBGAFCF_02878 1.72e-215 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
PIBGAFCF_02879 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIBGAFCF_02880 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
PIBGAFCF_02881 1.56e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PIBGAFCF_02882 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIBGAFCF_02883 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_02884 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PIBGAFCF_02885 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
PIBGAFCF_02886 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PIBGAFCF_02887 2.12e-185 yxaL - - S - - - PQQ-like domain
PIBGAFCF_02888 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
PIBGAFCF_02889 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PIBGAFCF_02890 1.16e-250 - - - EGP - - - Major Facilitator Superfamily
PIBGAFCF_02891 2.58e-86 yxaI - - S - - - membrane protein domain
PIBGAFCF_02892 2.86e-83 - - - E - - - Ring-cleavage extradiol dioxygenase
PIBGAFCF_02893 5.77e-56 - - - E - - - Ring-cleavage extradiol dioxygenase
PIBGAFCF_02894 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
PIBGAFCF_02895 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
PIBGAFCF_02896 9.59e-234 mrjp - - G - - - Major royal jelly protein
PIBGAFCF_02897 5.11e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_02898 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
PIBGAFCF_02899 2.97e-95 - - - K - - - Integron-associated effector binding protein
PIBGAFCF_02900 6.31e-98 yjhE - - S - - - Phage tail protein
PIBGAFCF_02901 7.62e-271 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
PIBGAFCF_02902 6.79e-147 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIBGAFCF_02903 1.56e-117 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIBGAFCF_02904 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
PIBGAFCF_02905 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PIBGAFCF_02906 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PIBGAFCF_02907 1.35e-216 ybaS - - S - - - Na -dependent transporter
PIBGAFCF_02908 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
PIBGAFCF_02909 9.92e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_02910 1.48e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_02911 1.12e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
PIBGAFCF_02912 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PIBGAFCF_02913 4.44e-291 ybbC - - S - - - protein conserved in bacteria
PIBGAFCF_02914 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PIBGAFCF_02915 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
PIBGAFCF_02916 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_02917 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIBGAFCF_02918 1.13e-76 ybbJ - - J - - - acetyltransferase
PIBGAFCF_02919 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
PIBGAFCF_02925 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_02926 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PIBGAFCF_02927 3.01e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIBGAFCF_02928 1.83e-290 ybbR - - S - - - protein conserved in bacteria
PIBGAFCF_02929 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIBGAFCF_02930 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIBGAFCF_02931 1.17e-21 - - - S - - - peptidyl-tyrosine sulfation
PIBGAFCF_02932 4.96e-56 - - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 ATPase activity
PIBGAFCF_02933 1.23e-119 - - - L - - - DNA polymerase III
PIBGAFCF_02934 5.91e-68 - - - S - - - ABC-2 family transporter protein
PIBGAFCF_02935 3.07e-124 ybdN - - - - - - -
PIBGAFCF_02936 9.57e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
PIBGAFCF_02937 2.34e-203 dkgB - - S - - - Aldo/keto reductase family
PIBGAFCF_02938 3.49e-134 yxaC - - M - - - effector of murein hydrolase
PIBGAFCF_02939 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
PIBGAFCF_02940 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_02941 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_02942 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PIBGAFCF_02943 7.04e-226 - - - T - - - COG4585 Signal transduction histidine kinase
PIBGAFCF_02944 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
PIBGAFCF_02945 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PIBGAFCF_02946 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PIBGAFCF_02947 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PIBGAFCF_02948 6.5e-33 - - - - - - - -
PIBGAFCF_02949 3.66e-103 - - - S - - - Domain of unknown function (DUF4879)
PIBGAFCF_02950 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
PIBGAFCF_02951 8.57e-136 yqeB - - - - - - -
PIBGAFCF_02952 2.17e-52 ybyB - - - - - - -
PIBGAFCF_02953 0.0 ybeC - - E - - - amino acid
PIBGAFCF_02954 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
PIBGAFCF_02955 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
PIBGAFCF_02956 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
PIBGAFCF_02957 1e-23 - - - S - - - Protein of unknown function (DUF2651)
PIBGAFCF_02958 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
PIBGAFCF_02960 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_02961 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
PIBGAFCF_02962 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PIBGAFCF_02963 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIBGAFCF_02964 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
PIBGAFCF_02965 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PIBGAFCF_02966 9.76e-52 ybfN - - - - - - -
PIBGAFCF_02967 1.78e-239 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PIBGAFCF_02968 1.51e-265 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIBGAFCF_02969 6.73e-245 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PIBGAFCF_02970 7.12e-303 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PIBGAFCF_02971 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
PIBGAFCF_02972 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PIBGAFCF_02973 5.86e-89 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PIBGAFCF_02974 4.31e-44 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PIBGAFCF_02975 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_02976 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
PIBGAFCF_02977 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
PIBGAFCF_02978 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
PIBGAFCF_02979 3.37e-195 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIBGAFCF_02980 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
PIBGAFCF_02981 1.9e-229 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PIBGAFCF_02982 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
PIBGAFCF_02983 3.11e-73 ydfQ - - CO - - - Thioredoxin
PIBGAFCF_02984 2.08e-15 - - - L - - - COG3666 Transposase and inactivated derivatives
PIBGAFCF_02985 2.71e-81 ycbP - - S - - - Protein of unknown function (DUF2512)
PIBGAFCF_02986 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PIBGAFCF_02987 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
PIBGAFCF_02988 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PIBGAFCF_02989 8.33e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PIBGAFCF_02990 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIBGAFCF_02991 3.97e-240 ycbU - - E - - - Selenocysteine lyase
PIBGAFCF_02992 1.47e-305 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
PIBGAFCF_02993 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PIBGAFCF_02994 1.17e-39 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PIBGAFCF_02995 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PIBGAFCF_02996 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
PIBGAFCF_02997 6.43e-211 yccK - - C - - - Aldo keto reductase
PIBGAFCF_02998 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
PIBGAFCF_02999 2.82e-300 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_03000 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_03001 5.55e-116 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PIBGAFCF_03002 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
PIBGAFCF_03003 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PIBGAFCF_03004 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PIBGAFCF_03005 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
PIBGAFCF_03006 1.86e-62 - - - K - - - Virulence activator alpha C-term
PIBGAFCF_03007 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PIBGAFCF_03008 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PIBGAFCF_03009 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PIBGAFCF_03010 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_03011 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
PIBGAFCF_03012 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PIBGAFCF_03013 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PIBGAFCF_03014 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
PIBGAFCF_03015 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
PIBGAFCF_03016 1.36e-245 yceH - - P - - - Belongs to the TelA family
PIBGAFCF_03017 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
PIBGAFCF_03019 4.98e-290 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PIBGAFCF_03020 1.2e-44 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PIBGAFCF_03021 6.79e-118 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PIBGAFCF_03022 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PIBGAFCF_03023 6.41e-261 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
PIBGAFCF_03024 2.88e-238 ycgA - - S - - - Membrane
PIBGAFCF_03025 9.33e-31 ycgA - - S - - - Membrane
PIBGAFCF_03026 1.04e-53 ycgB - - - - - - -
PIBGAFCF_03027 2.85e-15 - - - S - - - RDD family
PIBGAFCF_03028 1.55e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PIBGAFCF_03029 0.0 mdr - - EGP - - - the major facilitator superfamily
PIBGAFCF_03030 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_03032 8.55e-19 xkdS - - S - - - Protein of unknown function (DUF2634)
PIBGAFCF_03033 8.03e-141 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PIBGAFCF_03034 8.72e-34 xkdR - - S - - - Protein of unknown function (DUF2577)
PIBGAFCF_03035 1.23e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
PIBGAFCF_03036 1.29e-89 - - - K - - - MerR family transcriptional regulator
PIBGAFCF_03037 6.77e-21 xkdG - - S - - - Phage capsid family
PIBGAFCF_03038 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
PIBGAFCF_03039 4.16e-79 - - - K - - - Transcriptional regulator PadR-like family
PIBGAFCF_03040 3.5e-47 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PIBGAFCF_03042 1.84e-126 yqaC - - F - - - adenylate kinase activity
PIBGAFCF_03043 5.34e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_03044 5.62e-85 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PIBGAFCF_03045 2.76e-120 - - - S - - - DinB family
PIBGAFCF_03047 1.14e-187 supH - - S - - - hydrolase
PIBGAFCF_03048 5.2e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
PIBGAFCF_03049 7.33e-67 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
PIBGAFCF_03050 7.73e-85 - - - K - - - Helix-turn-helix domain, rpiR family
PIBGAFCF_03051 3.2e-65 - - - K - - - Helix-turn-helix domain, rpiR family
PIBGAFCF_03052 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PIBGAFCF_03053 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_03054 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
PIBGAFCF_03055 2.25e-227 romA - - S - - - Beta-lactamase superfamily domain
PIBGAFCF_03056 1.88e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIBGAFCF_03057 5.33e-211 yybE - - K - - - Transcriptional regulator
PIBGAFCF_03058 1.32e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_03059 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PIBGAFCF_03060 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
PIBGAFCF_03061 3.04e-120 yrhH - - Q - - - methyltransferase
PIBGAFCF_03062 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
PIBGAFCF_03063 4.62e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
PIBGAFCF_03064 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
PIBGAFCF_03065 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
PIBGAFCF_03066 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
PIBGAFCF_03067 1.35e-46 yrhC - - S - - - YrhC-like protein
PIBGAFCF_03068 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PIBGAFCF_03069 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
PIBGAFCF_03070 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIBGAFCF_03071 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
PIBGAFCF_03072 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
PIBGAFCF_03073 9.17e-119 yrrS - - S - - - Protein of unknown function (DUF1510)
PIBGAFCF_03074 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
PIBGAFCF_03075 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIBGAFCF_03076 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PIBGAFCF_03077 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
PIBGAFCF_03078 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PIBGAFCF_03079 4.49e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
PIBGAFCF_03080 7.74e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIBGAFCF_03081 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
PIBGAFCF_03082 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIBGAFCF_03083 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
PIBGAFCF_03084 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIBGAFCF_03085 4.09e-231 yrrI - - S - - - AI-2E family transporter
PIBGAFCF_03086 4.93e-100 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PIBGAFCF_03087 1.15e-52 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PIBGAFCF_03088 5.82e-185 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PIBGAFCF_03089 4.6e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PIBGAFCF_03090 1.41e-134 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PIBGAFCF_03091 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
PIBGAFCF_03092 8.4e-42 yrzR - - - - - - -
PIBGAFCF_03093 4.28e-99 yrrD - - S - - - protein conserved in bacteria
PIBGAFCF_03094 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIBGAFCF_03095 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
PIBGAFCF_03096 1.33e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIBGAFCF_03097 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PIBGAFCF_03098 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_03099 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PIBGAFCF_03100 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PIBGAFCF_03101 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PIBGAFCF_03102 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PIBGAFCF_03105 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
PIBGAFCF_03106 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIBGAFCF_03107 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIBGAFCF_03108 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIBGAFCF_03109 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PIBGAFCF_03110 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
PIBGAFCF_03111 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PIBGAFCF_03112 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PIBGAFCF_03113 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
PIBGAFCF_03114 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIBGAFCF_03115 1.16e-133 yrbG - - S - - - membrane
PIBGAFCF_03116 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
PIBGAFCF_03117 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
PIBGAFCF_03118 9.18e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PIBGAFCF_03119 1.12e-243 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PIBGAFCF_03120 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
PIBGAFCF_03121 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIBGAFCF_03122 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIBGAFCF_03123 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
PIBGAFCF_03125 1.26e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIBGAFCF_03126 4.39e-212 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
PIBGAFCF_03127 4.89e-262 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PIBGAFCF_03128 1.3e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
PIBGAFCF_03129 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
PIBGAFCF_03130 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PIBGAFCF_03131 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PIBGAFCF_03132 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PIBGAFCF_03133 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
PIBGAFCF_03134 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIBGAFCF_03135 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
PIBGAFCF_03136 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PIBGAFCF_03137 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
PIBGAFCF_03138 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PIBGAFCF_03139 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
PIBGAFCF_03140 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PIBGAFCF_03141 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PIBGAFCF_03142 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PIBGAFCF_03143 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
PIBGAFCF_03144 4.16e-200 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PIBGAFCF_03145 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
PIBGAFCF_03146 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PIBGAFCF_03147 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
PIBGAFCF_03148 2.51e-192 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
PIBGAFCF_03149 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PIBGAFCF_03150 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PIBGAFCF_03151 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIBGAFCF_03152 3.61e-34 - - - - - - - -
PIBGAFCF_03153 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PIBGAFCF_03154 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
PIBGAFCF_03155 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PIBGAFCF_03156 1.98e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
PIBGAFCF_03157 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PIBGAFCF_03158 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PIBGAFCF_03159 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
PIBGAFCF_03160 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PIBGAFCF_03161 3.63e-110 ysxD - - - - - - -
PIBGAFCF_03162 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PIBGAFCF_03163 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PIBGAFCF_03164 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
PIBGAFCF_03165 8.92e-291 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIBGAFCF_03166 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIBGAFCF_03167 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
PIBGAFCF_03168 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIBGAFCF_03169 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIBGAFCF_03170 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PIBGAFCF_03171 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PIBGAFCF_03172 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PIBGAFCF_03173 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PIBGAFCF_03174 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PIBGAFCF_03179 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PIBGAFCF_03180 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIBGAFCF_03181 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PIBGAFCF_03182 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
PIBGAFCF_03183 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PIBGAFCF_03184 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_03185 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_03186 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
PIBGAFCF_03187 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PIBGAFCF_03188 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PIBGAFCF_03189 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
PIBGAFCF_03190 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
PIBGAFCF_03191 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PIBGAFCF_03192 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIBGAFCF_03193 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PIBGAFCF_03194 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
PIBGAFCF_03195 4.79e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
PIBGAFCF_03196 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
PIBGAFCF_03197 2.18e-172 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
PIBGAFCF_03198 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_03199 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PIBGAFCF_03200 5.4e-149 ywbB - - S - - - Protein of unknown function (DUF2711)
PIBGAFCF_03201 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
PIBGAFCF_03202 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIBGAFCF_03203 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
PIBGAFCF_03204 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
PIBGAFCF_03205 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PIBGAFCF_03206 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIBGAFCF_03207 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIBGAFCF_03208 2.98e-247 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIBGAFCF_03209 2.36e-166 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIBGAFCF_03210 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
PIBGAFCF_03211 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PIBGAFCF_03212 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
PIBGAFCF_03213 3.52e-309 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
PIBGAFCF_03214 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
PIBGAFCF_03215 8.62e-236 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PIBGAFCF_03217 5.89e-138 - - - L - - - IstB-like ATP binding protein
PIBGAFCF_03218 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
PIBGAFCF_03219 1.88e-299 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
PIBGAFCF_03220 6.38e-87 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIBGAFCF_03222 7.67e-200 - - - - - - - -
PIBGAFCF_03223 2.14e-211 - - - L - - - AAA domain
PIBGAFCF_03224 1.56e-103 - - - - - - - -
PIBGAFCF_03225 0.0 - - - J - - - DnaB-like helicase C terminal domain
PIBGAFCF_03226 1.91e-260 - - - L - - - DNA primase activity
PIBGAFCF_03227 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PIBGAFCF_03228 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
PIBGAFCF_03229 9.77e-30 - - - S - - - protein conserved in bacteria
PIBGAFCF_03232 8.73e-92 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
PIBGAFCF_03233 2.83e-116 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PIBGAFCF_03235 1.87e-69 - 2.1.1.113, 2.1.1.72 - L ko:K00571,ko:K00590 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
PIBGAFCF_03236 5.68e-203 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
PIBGAFCF_03249 1.22e-88 - - - S - - - NrdI Flavodoxin like
PIBGAFCF_03250 1.15e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_03251 3.25e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_03252 3.71e-207 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_03254 2.37e-134 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_03255 2.83e-121 - - - L - - - HNH endonuclease
PIBGAFCF_03256 3.47e-55 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIBGAFCF_03258 6.38e-16 - - - O - - - Glutaredoxin
PIBGAFCF_03259 3.14e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PIBGAFCF_03263 2.21e-191 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIBGAFCF_03264 2.09e-35 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIBGAFCF_03267 7.41e-82 - - - - - - - -
PIBGAFCF_03280 4.03e-115 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIBGAFCF_03283 1.2e-276 - - - M - - - Parallel beta-helix repeats
PIBGAFCF_03284 2.22e-107 - - - S - - - Pfam:DUF867
PIBGAFCF_03286 2.54e-10 - - - S - - - YopX protein
PIBGAFCF_03289 4e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PIBGAFCF_03290 4.74e-177 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
PIBGAFCF_03292 8.7e-75 - - - - - - - -
PIBGAFCF_03294 2.26e-22 - - - - - - - -
PIBGAFCF_03298 1.93e-87 - 2.1.1.113 - L ko:K00590 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
PIBGAFCF_03299 5.48e-32 - - - - - - - -
PIBGAFCF_03302 3.18e-84 - - - N - - - bacterial-type flagellum assembly
PIBGAFCF_03311 8.46e-34 - - - - - - - -
PIBGAFCF_03312 5.7e-240 - - - - - - - -
PIBGAFCF_03320 3.23e-50 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
PIBGAFCF_03329 1.31e-134 - - - S - - - KAP family P-loop domain
PIBGAFCF_03334 4.89e-33 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PIBGAFCF_03335 6.01e-89 yoaW - - - - - - -
PIBGAFCF_03336 1.15e-12 - - - I - - - Acyltransferase family
PIBGAFCF_03337 1.34e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PIBGAFCF_03339 4.04e-101 - - - - - - - -
PIBGAFCF_03345 0.0 - - - S - - - ATP-dependent DNA helicase activity
PIBGAFCF_03347 6.58e-94 - - - S - - - N-methyltransferase activity
PIBGAFCF_03348 7.33e-188 - - - S - - - DNA binding
PIBGAFCF_03349 4.28e-276 - - - - - - - -
PIBGAFCF_03352 1.21e-71 - - - D - - - Tubulin/FtsZ family, GTPase domain
PIBGAFCF_03356 0.0 - - - S - - - RNA-directed RNA polymerase activity
PIBGAFCF_03357 6.84e-109 - - - - - - - -
PIBGAFCF_03358 2.98e-41 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIBGAFCF_03361 8.2e-287 - - - - - - - -
PIBGAFCF_03366 3.95e-107 - - - - - - - -
PIBGAFCF_03370 4.83e-84 - - - - - - - -
PIBGAFCF_03373 2.07e-70 - - - - - - - -
PIBGAFCF_03374 4.23e-111 - - - - - - - -
PIBGAFCF_03375 7.39e-146 - - - - - - - -
PIBGAFCF_03376 6.04e-78 - - - - - - - -
PIBGAFCF_03378 2.48e-64 - - - - - - - -
PIBGAFCF_03379 3.13e-42 - - - - - - - -
PIBGAFCF_03382 2.02e-106 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
PIBGAFCF_03383 5.1e-76 - - - - - - - -
PIBGAFCF_03384 2.22e-65 - - - - - - - -
PIBGAFCF_03385 4.94e-222 - - - A - - - Belongs to the 'phage' integrase family
PIBGAFCF_03390 6.52e-149 - - - - - - - -
PIBGAFCF_03391 0.0 - - - S - - - peptidoglycan catabolic process
PIBGAFCF_03392 8.77e-109 - - - S - - - Phage tail protein
PIBGAFCF_03393 3.62e-240 - - - S - - - Pfam Transposase IS66
PIBGAFCF_03394 2e-136 - - - - - - - -
PIBGAFCF_03395 0.0 - - - M - - - Pectate lyase superfamily protein
PIBGAFCF_03396 1.4e-93 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PIBGAFCF_03398 1.76e-43 - - - S - - - Bacteriophage holin
PIBGAFCF_03400 5.07e-06 - - - - - - - -
PIBGAFCF_03401 1.94e-122 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PIBGAFCF_03403 8.79e-283 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIBGAFCF_03404 2.1e-52 - - - S - - - YolD-like protein
PIBGAFCF_03405 4.46e-26 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
PIBGAFCF_03407 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
PIBGAFCF_03409 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
PIBGAFCF_03410 5.52e-28 - - - S - - - YopX protein
PIBGAFCF_03412 1.54e-152 yqaM - - L - - - IstB-like ATP binding protein
PIBGAFCF_03413 4.55e-36 yqaL - - L - - - DnaD domain protein
PIBGAFCF_03414 4.78e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
PIBGAFCF_03415 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
PIBGAFCF_03419 3.27e-110 - - - - - - - -
PIBGAFCF_03420 4.76e-76 - - - S - - - DNA binding
PIBGAFCF_03421 2.39e-48 - - - - - - - -
PIBGAFCF_03422 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_03423 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_03424 8.41e-82 - - - - - - - -
PIBGAFCF_03425 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
PIBGAFCF_03426 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
PIBGAFCF_03427 1.16e-43 - - - L - - - Arm DNA-binding domain
PIBGAFCF_03428 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIBGAFCF_03429 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIBGAFCF_03430 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PIBGAFCF_03431 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
PIBGAFCF_03432 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PIBGAFCF_03433 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PIBGAFCF_03434 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIBGAFCF_03435 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PIBGAFCF_03436 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
PIBGAFCF_03437 1.64e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIBGAFCF_03438 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PIBGAFCF_03439 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
PIBGAFCF_03440 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
PIBGAFCF_03441 1.04e-219 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PIBGAFCF_03444 1.35e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PIBGAFCF_03446 2.08e-54 - - - S - - - dUTPase
PIBGAFCF_03449 2.62e-08 - - - S - - - YopX protein
PIBGAFCF_03454 3.27e-63 - - - - - - - -
PIBGAFCF_03456 1.76e-22 - - - V - - - VanZ like family
PIBGAFCF_03457 5.88e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PIBGAFCF_03459 1.74e-17 - - - K - - - Transcriptional regulator
PIBGAFCF_03462 7.49e-103 yqaS - - L - - - DNA packaging
PIBGAFCF_03463 9.66e-225 - - - S - - - Pfam:Terminase_3C
PIBGAFCF_03464 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
PIBGAFCF_03465 1.53e-116 - - - S - - - Phage Mu protein F like protein
PIBGAFCF_03467 3.82e-56 - - - S - - - Phage minor structural protein GP20
PIBGAFCF_03468 1.85e-61 - - - S - - - viral capsid
PIBGAFCF_03471 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
PIBGAFCF_03472 7.37e-38 - - - S - - - Phage head-tail joining protein
PIBGAFCF_03473 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PIBGAFCF_03474 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
PIBGAFCF_03475 3.23e-44 - - - S - - - Phage tail tube protein
PIBGAFCF_03477 1.85e-186 - - - - - - - -
PIBGAFCF_03479 3.11e-217 - - - L - - - Phage minor structural protein
PIBGAFCF_03480 1.8e-21 - - - S - - - peptidoglycan catabolic process
PIBGAFCF_03484 1.19e-40 xhlA - - S - - - Haemolysin XhlA
PIBGAFCF_03485 2.07e-37 xhlB - - S - - - SPP1 phage holin
PIBGAFCF_03486 2e-155 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PIBGAFCF_03489 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
PIBGAFCF_03491 2.21e-81 - - - - - - - -
PIBGAFCF_03492 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
PIBGAFCF_03493 9.34e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PIBGAFCF_03494 9.02e-311 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
PIBGAFCF_03495 4.48e-211 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PIBGAFCF_03496 5.98e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
PIBGAFCF_03497 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
PIBGAFCF_03498 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIBGAFCF_03499 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
PIBGAFCF_03500 1.33e-199 ydjI - - S - - - virion core protein (lumpy skin disease virus)
PIBGAFCF_03501 0.0 oatA - - I - - - Acyltransferase family
PIBGAFCF_03502 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
PIBGAFCF_03503 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_03504 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PIBGAFCF_03505 4.58e-82 ydjM - - M - - - Lytic transglycolase
PIBGAFCF_03506 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
PIBGAFCF_03508 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
PIBGAFCF_03509 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
PIBGAFCF_03510 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PIBGAFCF_03511 7.59e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIBGAFCF_03512 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
PIBGAFCF_03513 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PIBGAFCF_03514 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PIBGAFCF_03515 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PIBGAFCF_03516 8.68e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PIBGAFCF_03517 0.0 - - - S - - - Domain of unknown function (DUF4179)
PIBGAFCF_03518 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PIBGAFCF_03519 4.87e-165 yebC - - M - - - Membrane
PIBGAFCF_03521 1.08e-119 yebE - - S - - - UPF0316 protein
PIBGAFCF_03522 1.88e-39 yebG - - S - - - NETI protein
PIBGAFCF_03523 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PIBGAFCF_03524 1.15e-280 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIBGAFCF_03525 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIBGAFCF_03526 3.8e-163 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PIBGAFCF_03527 2.57e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIBGAFCF_03528 4.32e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIBGAFCF_03529 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIBGAFCF_03530 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIBGAFCF_03531 2.08e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PIBGAFCF_03532 1.16e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIBGAFCF_03533 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PIBGAFCF_03534 4.29e-293 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PIBGAFCF_03535 4.48e-81 - - - K - - - helix_turn_helix ASNC type
PIBGAFCF_03536 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
PIBGAFCF_03537 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
PIBGAFCF_03538 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
PIBGAFCF_03539 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
PIBGAFCF_03540 2.03e-67 yerC - - S - - - protein conserved in bacteria
PIBGAFCF_03541 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
PIBGAFCF_03542 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PIBGAFCF_03543 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PIBGAFCF_03544 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIBGAFCF_03545 2.25e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
PIBGAFCF_03546 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
PIBGAFCF_03547 1.61e-155 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PIBGAFCF_03548 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIBGAFCF_03549 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIBGAFCF_03550 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIBGAFCF_03551 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIBGAFCF_03552 1.01e-189 yerO - - K - - - Transcriptional regulator
PIBGAFCF_03553 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PIBGAFCF_03554 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PIBGAFCF_03555 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIBGAFCF_03556 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
PIBGAFCF_03557 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PIBGAFCF_03558 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
PIBGAFCF_03559 5.92e-51 - - - S - - - Protein of unknown function, DUF600
PIBGAFCF_03560 2.35e-73 - - - S - - - Protein of unknown function, DUF600
PIBGAFCF_03561 2.48e-66 - - - S - - - Protein of unknown function, DUF600
PIBGAFCF_03562 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
PIBGAFCF_03563 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
PIBGAFCF_03564 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
PIBGAFCF_03566 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
PIBGAFCF_03567 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
PIBGAFCF_03568 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
PIBGAFCF_03569 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
PIBGAFCF_03570 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
PIBGAFCF_03572 1.26e-147 yetF - - S - - - membrane
PIBGAFCF_03573 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
PIBGAFCF_03574 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_03575 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIBGAFCF_03576 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
PIBGAFCF_03577 2.59e-73 - - - H - - - riboflavin kinase activity
PIBGAFCF_03578 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
PIBGAFCF_03579 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
PIBGAFCF_03580 3.35e-246 yetM - - CH - - - FAD binding domain
PIBGAFCF_03581 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
PIBGAFCF_03582 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PIBGAFCF_03584 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PIBGAFCF_03585 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
PIBGAFCF_03586 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
PIBGAFCF_03587 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
PIBGAFCF_03588 3.25e-272 yfnE - - S - - - Glycosyltransferase like family 2
PIBGAFCF_03589 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
PIBGAFCF_03590 4.78e-272 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_03591 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
PIBGAFCF_03592 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIBGAFCF_03593 3.69e-165 yfmS - - NT - - - chemotaxis protein
PIBGAFCF_03594 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PIBGAFCF_03595 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PIBGAFCF_03596 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIBGAFCF_03597 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
PIBGAFCF_03598 6.17e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
PIBGAFCF_03599 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIBGAFCF_03600 2.32e-260 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
PIBGAFCF_03601 3.25e-64 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PIBGAFCF_03602 1.41e-99 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PIBGAFCF_03603 9.03e-33 - - - S - - - Protein of unknown function (DUF3212)
PIBGAFCF_03604 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
PIBGAFCF_03605 5.26e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PIBGAFCF_03606 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PIBGAFCF_03611 3.08e-92 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
PIBGAFCF_03612 0.0 ywpD - - T - - - Histidine kinase
PIBGAFCF_03613 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
PIBGAFCF_03614 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PIBGAFCF_03615 3.06e-61 yutD - - S - - - protein conserved in bacteria
PIBGAFCF_03616 3e-93 yutE - - S - - - Protein of unknown function DUF86
PIBGAFCF_03617 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIBGAFCF_03618 4.38e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PIBGAFCF_03619 5.56e-244 yutH - - S - - - Spore coat protein
PIBGAFCF_03620 1.6e-305 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PIBGAFCF_03621 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PIBGAFCF_03622 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIBGAFCF_03623 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
PIBGAFCF_03624 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
PIBGAFCF_03625 2.61e-70 yuzD - - S - - - protein conserved in bacteria
PIBGAFCF_03626 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PIBGAFCF_03627 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
PIBGAFCF_03628 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIBGAFCF_03629 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIBGAFCF_03630 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
PIBGAFCF_03631 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_03632 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
PIBGAFCF_03634 1.77e-42 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
PIBGAFCF_03636 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PIBGAFCF_03637 1.09e-86 - - - CP - - - Membrane
PIBGAFCF_03638 1.57e-37 - - - - - - - -
PIBGAFCF_03639 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIBGAFCF_03641 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
PIBGAFCF_03642 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PIBGAFCF_03643 1.21e-45 yuiB - - S - - - Putative membrane protein
PIBGAFCF_03644 2.23e-149 yuiC - - S - - - protein conserved in bacteria
PIBGAFCF_03645 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PIBGAFCF_03646 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PIBGAFCF_03647 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
PIBGAFCF_03648 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
PIBGAFCF_03649 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
PIBGAFCF_03650 2.31e-198 eSD - - S ko:K07017 - ko00000 Putative esterase
PIBGAFCF_03651 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PIBGAFCF_03652 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PIBGAFCF_03653 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
PIBGAFCF_03654 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
PIBGAFCF_03655 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_03656 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
PIBGAFCF_03657 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PIBGAFCF_03658 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PIBGAFCF_03659 1.66e-288 yukF - - QT - - - Transcriptional regulator
PIBGAFCF_03660 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
PIBGAFCF_03661 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
PIBGAFCF_03662 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
PIBGAFCF_03663 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PIBGAFCF_03664 0.0 yueB - - S - - - type VII secretion protein EsaA
PIBGAFCF_03665 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
PIBGAFCF_03666 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_03667 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
PIBGAFCF_03668 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
PIBGAFCF_03669 2.31e-232 yueF - - S - - - transporter activity
PIBGAFCF_03670 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
PIBGAFCF_03671 1.1e-50 yueH - - S - - - YueH-like protein
PIBGAFCF_03672 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
PIBGAFCF_03673 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
PIBGAFCF_03674 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIBGAFCF_03675 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
PIBGAFCF_03676 1.59e-62 yuzC - - - - - - -
PIBGAFCF_03677 1.87e-11 - - - S - - - DegQ (SacQ) family
PIBGAFCF_03678 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
PIBGAFCF_03680 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
PIBGAFCF_03681 1.1e-73 ygzB - - S - - - UPF0295 protein
PIBGAFCF_03682 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PIBGAFCF_03683 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
PIBGAFCF_03684 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PIBGAFCF_03685 1.76e-237 ygaE - - S - - - Membrane
PIBGAFCF_03686 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
PIBGAFCF_03687 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PIBGAFCF_03688 1.4e-49 ygaB - - S - - - YgaB-like protein
PIBGAFCF_03689 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
PIBGAFCF_03690 2.02e-168 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_03691 1.47e-49 yfhS - - - - - - -
PIBGAFCF_03692 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
PIBGAFCF_03693 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
PIBGAFCF_03694 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PIBGAFCF_03695 1.29e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PIBGAFCF_03696 5.37e-156 - - - S - - - Alpha/beta hydrolase family
PIBGAFCF_03697 1.7e-47 yfhL - - S - - - SdpI/YhfL protein family
PIBGAFCF_03698 2.3e-112 yfhK - - T - - - Bacterial SH3 domain homologues
PIBGAFCF_03699 1.49e-58 yfhJ - - S - - - WVELL protein
PIBGAFCF_03700 6.62e-203 mpr - - M - - - Belongs to the peptidase S1B family
PIBGAFCF_03702 6.7e-231 yfhI - - EGP - - - -transporter
PIBGAFCF_03703 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
PIBGAFCF_03704 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PIBGAFCF_03705 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
PIBGAFCF_03707 6.01e-33 yfhD - - S - - - YfhD-like protein
PIBGAFCF_03708 3.09e-133 yfhC - - C - - - nitroreductase
PIBGAFCF_03709 1.27e-193 yfhB - - S - - - PhzF family
PIBGAFCF_03710 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIBGAFCF_03711 2.11e-103 yfiV - - K - - - transcriptional
PIBGAFCF_03712 0.0 yfiU - - EGP - - - the major facilitator superfamily
PIBGAFCF_03713 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
PIBGAFCF_03714 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PIBGAFCF_03715 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PIBGAFCF_03716 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
PIBGAFCF_03717 1e-119 padR - - K - - - transcriptional
PIBGAFCF_03718 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PIBGAFCF_03719 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PIBGAFCF_03720 4.18e-196 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PIBGAFCF_03721 7.86e-82 yfiD3 - - S - - - DoxX
PIBGAFCF_03722 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PIBGAFCF_03723 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
PIBGAFCF_03724 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
PIBGAFCF_03725 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_03726 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PIBGAFCF_03727 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PIBGAFCF_03728 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
PIBGAFCF_03729 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
PIBGAFCF_03730 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIBGAFCF_03731 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIBGAFCF_03732 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIBGAFCF_03733 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIBGAFCF_03734 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
PIBGAFCF_03735 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIBGAFCF_03736 1.83e-60 - - - S - - - YfzA-like protein
PIBGAFCF_03744 0.0 - - - KLT - - - Protein kinase domain
PIBGAFCF_03745 7.56e-305 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PIBGAFCF_03746 3.05e-93 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
PIBGAFCF_03747 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
PIBGAFCF_03748 0.0 yclG - - M - - - Pectate lyase superfamily protein
PIBGAFCF_03750 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
PIBGAFCF_03751 6.53e-290 gerKC - - S ko:K06297 - ko00000 spore germination
PIBGAFCF_03752 5.7e-243 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
PIBGAFCF_03753 8.5e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIBGAFCF_03754 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIBGAFCF_03755 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PIBGAFCF_03756 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PIBGAFCF_03757 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_03758 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PIBGAFCF_03759 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
PIBGAFCF_03760 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PIBGAFCF_03761 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
PIBGAFCF_03762 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_03763 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
PIBGAFCF_03764 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PIBGAFCF_03767 1.28e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PIBGAFCF_03768 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_03769 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIBGAFCF_03770 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_03771 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
PIBGAFCF_03772 1.98e-313 ycnB - - EGP - - - the major facilitator superfamily
PIBGAFCF_03773 4.78e-192 ycnC - - K - - - Transcriptional regulator
PIBGAFCF_03774 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
PIBGAFCF_03775 2.79e-59 ycnE - - S - - - Monooxygenase
PIBGAFCF_03776 2.56e-66 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PIBGAFCF_03777 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIBGAFCF_03778 2.59e-279 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIBGAFCF_03779 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIBGAFCF_03780 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
PIBGAFCF_03781 1.82e-181 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_03782 6.58e-128 ycnI - - S - - - protein conserved in bacteria
PIBGAFCF_03783 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
PIBGAFCF_03784 1.15e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PIBGAFCF_03785 2.18e-69 - - - - - - - -
PIBGAFCF_03786 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
PIBGAFCF_03787 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PIBGAFCF_03788 2.79e-255 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
PIBGAFCF_03789 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PIBGAFCF_03791 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PIBGAFCF_03792 1.66e-169 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
PIBGAFCF_03793 2.33e-265 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
PIBGAFCF_03794 7.99e-182 ycsI - - S - - - Belongs to the D-glutamate cyclase family
PIBGAFCF_03795 1.75e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
PIBGAFCF_03796 1.09e-227 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
PIBGAFCF_03797 2.47e-162 kipR - - K - - - Transcriptional regulator
PIBGAFCF_03798 1.97e-143 ycsK - - E - - - anatomical structure formation involved in morphogenesis
PIBGAFCF_03800 2.73e-71 yczJ - - S - - - biosynthesis
PIBGAFCF_03801 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
PIBGAFCF_03802 1.53e-213 ycsN - - S - - - Oxidoreductase
PIBGAFCF_03803 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
PIBGAFCF_03804 0.0 ydaB - - IQ - - - acyl-CoA ligase
PIBGAFCF_03805 2.17e-195 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIBGAFCF_03806 3.59e-118 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
PIBGAFCF_03807 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PIBGAFCF_03808 4.32e-100 ydaG - - S - - - general stress protein
PIBGAFCF_03809 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PIBGAFCF_03810 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
PIBGAFCF_03811 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PIBGAFCF_03812 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIBGAFCF_03813 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
PIBGAFCF_03814 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
PIBGAFCF_03815 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
PIBGAFCF_03816 1.08e-188 ydaM - - M - - - Glycosyl transferase family group 2
PIBGAFCF_03817 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
PIBGAFCF_03818 0.0 ydaO - - E - - - amino acid
PIBGAFCF_03819 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PIBGAFCF_03820 5.03e-80 - - - K - - - acetyltransferase
PIBGAFCF_03822 3.35e-88 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PIBGAFCF_03823 1.04e-83 - - - - - - - -
PIBGAFCF_03824 7.22e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
PIBGAFCF_03825 1.01e-49 - - - S - - - Domain of unknown function (DUF1874)
PIBGAFCF_03826 0.0 yddE - - S - - - AAA-like domain
PIBGAFCF_03827 8.78e-96 yddD - - S - - - TcpE family
PIBGAFCF_03828 2.72e-33 yddC - - - - - - -
PIBGAFCF_03829 1.41e-162 yddB - - S - - - Conjugative transposon protein TcpC
PIBGAFCF_03830 5.8e-54 yddA - - - - - - -
PIBGAFCF_03834 3.25e-232 nicK - - L ko:K07467 - ko00000 Replication initiation factor
PIBGAFCF_03835 1.56e-302 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
PIBGAFCF_03837 1.87e-50 - - - S - - - Bacterial protein of unknown function (DUF961)
PIBGAFCF_03839 2.18e-34 - - - - - - - -
PIBGAFCF_03840 4.29e-71 - - - K - - - Transcriptional
PIBGAFCF_03841 9.84e-80 - - - E - - - Pfam:DUF955
PIBGAFCF_03842 3.44e-180 ydcL - - L - - - Belongs to the 'phage' integrase family
PIBGAFCF_03843 6.4e-31 - - - S - - - YesK-like protein
PIBGAFCF_03846 4.65e-40 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PIBGAFCF_03850 4.24e-62 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PIBGAFCF_03851 5.14e-10 - - - S - - - YvrJ protein family
PIBGAFCF_03859 3.37e-73 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PIBGAFCF_03860 1.78e-21 - - - - - - - -
PIBGAFCF_03861 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
PIBGAFCF_03862 3.58e-135 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
PIBGAFCF_03863 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIBGAFCF_03864 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PIBGAFCF_03865 3.28e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
PIBGAFCF_03866 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
PIBGAFCF_03867 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PIBGAFCF_03868 3.11e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
PIBGAFCF_03869 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
PIBGAFCF_03870 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PIBGAFCF_03871 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PIBGAFCF_03872 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIBGAFCF_03873 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
PIBGAFCF_03874 7.05e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIBGAFCF_03875 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
PIBGAFCF_03876 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
PIBGAFCF_03877 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
PIBGAFCF_03878 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIBGAFCF_03879 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIBGAFCF_03880 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PIBGAFCF_03881 2.25e-74 ydbP - - CO - - - Thioredoxin
PIBGAFCF_03882 1.34e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIBGAFCF_03883 6.11e-15 - - - S - - - Fur-regulated basic protein A
PIBGAFCF_03884 2.36e-17 - - - S - - - Fur-regulated basic protein B
PIBGAFCF_03885 7.84e-256 ydbM - - I - - - acyl-CoA dehydrogenase
PIBGAFCF_03886 1.32e-69 ydbL - - - - - - -
PIBGAFCF_03887 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PIBGAFCF_03888 1.79e-216 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PIBGAFCF_03889 1.85e-225 ydbI - - S - - - AI-2E family transporter
PIBGAFCF_03890 1.4e-218 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIBGAFCF_03891 8.46e-36 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIBGAFCF_03892 2.66e-146 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PIBGAFCF_03893 4.81e-195 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PIBGAFCF_03894 2.87e-157 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PIBGAFCF_03895 2.07e-171 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PIBGAFCF_03896 8.49e-52 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PIBGAFCF_03897 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
PIBGAFCF_03898 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
PIBGAFCF_03899 1.04e-75 ydbB - - G - - - Cupin domain
PIBGAFCF_03900 9.56e-08 gsiB - - S ko:K06884 - ko00000 general stress protein
PIBGAFCF_03901 6.45e-174 ydbA - - P - - - EcsC protein family
PIBGAFCF_03902 1.7e-64 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PIBGAFCF_03903 2.74e-96 yvaD - - S - - - Family of unknown function (DUF5360)
PIBGAFCF_03904 4.61e-44 ydaT - - - - - - -
PIBGAFCF_03907 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PIBGAFCF_03908 1.06e-53 - - - - - - - -
PIBGAFCF_03912 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PIBGAFCF_03913 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
PIBGAFCF_03914 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
PIBGAFCF_03915 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
PIBGAFCF_03916 2.07e-237 ybeC - - E - - - amino acid
PIBGAFCF_03917 1.04e-86 ybeC - - E - - - amino acid
PIBGAFCF_03918 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
PIBGAFCF_03919 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PIBGAFCF_03920 1.02e-38 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
PIBGAFCF_03921 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
PIBGAFCF_03922 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
PIBGAFCF_03923 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
PIBGAFCF_03924 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
PIBGAFCF_03925 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
PIBGAFCF_03927 3.98e-311 pbpE - - V - - - Beta-lactamase
PIBGAFCF_03929 1.11e-168 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PIBGAFCF_03930 8.62e-69 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PIBGAFCF_03931 1.47e-144 ydhC - - K - - - FCD
PIBGAFCF_03932 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
PIBGAFCF_03933 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
PIBGAFCF_03934 1.15e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PIBGAFCF_03935 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PIBGAFCF_03936 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
PIBGAFCF_03937 2.15e-99 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
PIBGAFCF_03938 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
PIBGAFCF_03939 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
PIBGAFCF_03940 5.7e-281 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIBGAFCF_03941 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PIBGAFCF_03942 3.1e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
PIBGAFCF_03943 1.37e-188 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_03944 4.32e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
PIBGAFCF_03945 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
PIBGAFCF_03946 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
PIBGAFCF_03947 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
PIBGAFCF_03948 4.73e-47 yraG - - - ko:K06440 - ko00000 -
PIBGAFCF_03949 4.76e-84 yraF - - M - - - Spore coat protein
PIBGAFCF_03950 2.3e-277 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PIBGAFCF_03951 4.86e-33 yraE - - - ko:K06440 - ko00000 -
PIBGAFCF_03952 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
PIBGAFCF_03953 4.86e-315 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIBGAFCF_03954 1.42e-190 ydeK - - EG - - - -transporter
PIBGAFCF_03955 2.13e-129 ydeS - - K - - - Transcriptional regulator
PIBGAFCF_03956 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
PIBGAFCF_03957 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
PIBGAFCF_03958 5.46e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
PIBGAFCF_03959 6.33e-278 nhaC_1 - - C - - - antiporter
PIBGAFCF_03960 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
PIBGAFCF_03961 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
PIBGAFCF_03962 3.65e-206 - - - S - - - Sodium Bile acid symporter family
PIBGAFCF_03963 7.14e-63 ydeH - - - - - - -
PIBGAFCF_03964 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PIBGAFCF_03966 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PIBGAFCF_03967 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PIBGAFCF_03968 1.19e-124 yrkC - - G - - - Cupin domain
PIBGAFCF_03969 3.58e-201 - - - S - - - SNARE associated Golgi protein
PIBGAFCF_03970 8.48e-196 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
PIBGAFCF_03971 2.6e-90 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_03972 6.11e-128 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
PIBGAFCF_03974 5.81e-57 - - - S - - - Patatin-like phospholipase
PIBGAFCF_03975 1.41e-63 - - - S - - - Patatin-like phospholipase
PIBGAFCF_03976 3.96e-238 ydeG - - EGP - - - Major facilitator superfamily
PIBGAFCF_03977 4.32e-298 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIBGAFCF_03978 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
PIBGAFCF_03979 1e-131 - - - S - - - Protein of unknown function (DUF2812)
PIBGAFCF_03980 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PIBGAFCF_03981 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
PIBGAFCF_03982 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIBGAFCF_03983 1.19e-99 - - - K - - - Transcriptional regulator
PIBGAFCF_03985 1.85e-59 - - - - - - - -
PIBGAFCF_03987 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIBGAFCF_03988 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PIBGAFCF_03989 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
PIBGAFCF_03991 3.36e-87 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PIBGAFCF_03992 2.14e-56 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PIBGAFCF_03993 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
PIBGAFCF_03994 7.99e-37 yfjT - - - - - - -
PIBGAFCF_03995 9.38e-279 yfkA - - S - - - YfkB-like domain
PIBGAFCF_03996 5.34e-182 yfkC - - M - - - Mechanosensitive ion channel
PIBGAFCF_03997 4.99e-180 yfkD - - S - - - YfkD-like protein
PIBGAFCF_03998 3.14e-234 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
PIBGAFCF_03999 1.55e-273 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_04000 8.85e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PIBGAFCF_04001 2.71e-63 yfkI - - S - - - gas vesicle protein
PIBGAFCF_04002 1.38e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIBGAFCF_04003 7.02e-40 yfkK - - S - - - Belongs to the UPF0435 family
PIBGAFCF_04004 1.23e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PIBGAFCF_04005 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PIBGAFCF_04006 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIBGAFCF_04007 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PIBGAFCF_04008 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PIBGAFCF_04009 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PIBGAFCF_04010 5.49e-235 yibE - - S - - - YibE/F-like protein
PIBGAFCF_04011 1.06e-160 yibF - - S - - - YibE/F-like protein
PIBGAFCF_04012 1.34e-154 frp - - C - - - nitroreductase
PIBGAFCF_04013 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
PIBGAFCF_04014 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PIBGAFCF_04015 1.5e-311 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PIBGAFCF_04016 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
PIBGAFCF_04017 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
PIBGAFCF_04018 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PIBGAFCF_04019 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
PIBGAFCF_04020 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PIBGAFCF_04021 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
PIBGAFCF_04022 3.41e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PIBGAFCF_04023 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PIBGAFCF_04024 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
PIBGAFCF_04025 5.69e-26 yflI - - - - - - -
PIBGAFCF_04026 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
PIBGAFCF_04027 1.9e-153 yflK - - S - - - protein conserved in bacteria
PIBGAFCF_04028 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PIBGAFCF_04029 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PIBGAFCF_04030 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PIBGAFCF_04031 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PIBGAFCF_04032 1.12e-216 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
PIBGAFCF_04033 1.76e-108 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PIBGAFCF_04034 1.92e-182 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PIBGAFCF_04035 5.91e-148 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PIBGAFCF_04036 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PIBGAFCF_04037 0.0 - - - M - - - cell wall anchor domain
PIBGAFCF_04038 0.0 - - - M - - - cell wall anchor domain
PIBGAFCF_04039 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
PIBGAFCF_04044 3.54e-282 - - - M - - - domain protein
PIBGAFCF_04045 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIBGAFCF_04046 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIBGAFCF_04047 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
PIBGAFCF_04048 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIBGAFCF_04049 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
PIBGAFCF_04050 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIBGAFCF_04051 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIBGAFCF_04052 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIBGAFCF_04053 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIBGAFCF_04054 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
PIBGAFCF_04055 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIBGAFCF_04056 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIBGAFCF_04057 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PIBGAFCF_04058 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PIBGAFCF_04059 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
PIBGAFCF_04060 2.76e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PIBGAFCF_04061 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
PIBGAFCF_04062 2.63e-74 yhhY - - K - - - FR47-like protein
PIBGAFCF_04063 3.84e-215 yyaD - - S - - - Membrane
PIBGAFCF_04064 1.82e-45 yyzM - - S - - - protein conserved in bacteria
PIBGAFCF_04065 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIBGAFCF_04066 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIBGAFCF_04067 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PIBGAFCF_04068 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIBGAFCF_04069 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIBGAFCF_04070 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
PIBGAFCF_04071 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIBGAFCF_04072 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PIBGAFCF_04073 6.01e-217 ccpB - - K - - - Transcriptional regulator
PIBGAFCF_04074 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_04075 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
PIBGAFCF_04076 4.75e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
PIBGAFCF_04077 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PIBGAFCF_04078 7.1e-207 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PIBGAFCF_04079 7.25e-88 ynaF - - - - - - -
PIBGAFCF_04080 3.34e-36 - - - - - - - -
PIBGAFCF_04081 8.63e-130 - - - S - - - Alpha/beta hydrolase family
PIBGAFCF_04082 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PIBGAFCF_04083 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
PIBGAFCF_04084 7.24e-97 yybA - - K - - - transcriptional
PIBGAFCF_04085 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PIBGAFCF_04086 2.55e-85 - - - K - - - Winged helix DNA-binding domain
PIBGAFCF_04087 1.56e-144 ydgI - - C - - - nitroreductase
PIBGAFCF_04088 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
PIBGAFCF_04089 1.96e-184 - - - G - - - Major Facilitator Superfamily
PIBGAFCF_04090 3.74e-115 - - - S - - - PFAM DinB family protein
PIBGAFCF_04091 7.61e-142 - - - K - - - FCD domain
PIBGAFCF_04092 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PIBGAFCF_04093 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
PIBGAFCF_04094 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PIBGAFCF_04095 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
PIBGAFCF_04096 1.79e-84 yybR - - K - - - Transcriptional regulator
PIBGAFCF_04097 3.93e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
PIBGAFCF_04099 8.64e-189 yybS - - S - - - membrane
PIBGAFCF_04100 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PIBGAFCF_04101 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PIBGAFCF_04102 4.29e-103 - - - KLT - - - COG0515 Serine threonine protein kinase
PIBGAFCF_04103 1.44e-150 - - - S - - - GlcNAc-PI de-N-acetylase
PIBGAFCF_04104 3.93e-279 - - - M - - - Glycosyltransferase Family 4
PIBGAFCF_04105 2.87e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
PIBGAFCF_04106 3.74e-242 - - - S - - - Ecdysteroid kinase
PIBGAFCF_04107 4.7e-272 - - - M - - - Glycosyltransferase Family 4
PIBGAFCF_04108 1.21e-23 yycC - - K - - - YycC-like protein
PIBGAFCF_04110 5.03e-35 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PIBGAFCF_04111 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PIBGAFCF_04112 1.06e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIBGAFCF_04113 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIBGAFCF_04118 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIBGAFCF_04119 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PIBGAFCF_04120 0.0 yycH - - S - - - protein conserved in bacteria
PIBGAFCF_04121 1.1e-191 yycI - - S - - - protein conserved in bacteria
PIBGAFCF_04122 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PIBGAFCF_04123 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIBGAFCF_04124 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
PIBGAFCF_04125 5.56e-07 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
PIBGAFCF_04126 9.72e-101 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
PIBGAFCF_04127 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PIBGAFCF_04128 8.24e-255 - - - S - - - Major Facilitator Superfamily
PIBGAFCF_04129 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PIBGAFCF_04130 3.82e-57 sdpR - - K - - - transcriptional
PIBGAFCF_04131 1.27e-92 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PIBGAFCF_04132 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
PIBGAFCF_04133 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PIBGAFCF_04134 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PIBGAFCF_04135 2.05e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
PIBGAFCF_04137 1.4e-94 yycN - - K - - - Acetyltransferase
PIBGAFCF_04138 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PIBGAFCF_04139 6.27e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PIBGAFCF_04140 5.96e-264 yycP - - - - - - -
PIBGAFCF_04144 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIBGAFCF_04145 0.0 - - - L - - - AAA ATPase domain
PIBGAFCF_04146 2.15e-301 - - - L - - - AAA domain
PIBGAFCF_04147 6.73e-20 - - - L - - - AAA domain
PIBGAFCF_04148 6.58e-27 - - - - - - - -
PIBGAFCF_04149 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
PIBGAFCF_04150 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PIBGAFCF_04151 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
PIBGAFCF_04152 1.76e-147 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PIBGAFCF_04153 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PIBGAFCF_04154 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PIBGAFCF_04155 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PIBGAFCF_04156 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
PIBGAFCF_04157 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PIBGAFCF_04158 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIBGAFCF_04162 5.52e-77 yddG - - S - - - maturation of SSU-rRNA
PIBGAFCF_04163 7.23e-201 yddH - - M - - - Lysozyme-like
PIBGAFCF_04164 6.62e-74 yddI - - - - - - -
PIBGAFCF_04165 6.17e-48 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
PIBGAFCF_04168 5.51e-86 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PIBGAFCF_04170 1.06e-176 - - - I ko:K01066 - ko00000,ko01000 esterase
PIBGAFCF_04171 3.54e-62 ohrB - - O - - - OsmC-like protein
PIBGAFCF_04172 7.77e-65 ohrR - - K - - - Transcriptional regulator
PIBGAFCF_04173 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
PIBGAFCF_04174 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
PIBGAFCF_04175 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIBGAFCF_04176 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIBGAFCF_04177 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIBGAFCF_04178 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIBGAFCF_04179 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
PIBGAFCF_04180 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
PIBGAFCF_04181 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
PIBGAFCF_04182 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
PIBGAFCF_04184 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PIBGAFCF_04185 9.36e-278 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIBGAFCF_04186 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PIBGAFCF_04187 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PIBGAFCF_04188 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PIBGAFCF_04189 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PIBGAFCF_04190 1.64e-224 yaaC - - S - - - YaaC-like Protein
PIBGAFCF_04191 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
PIBGAFCF_04192 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIBGAFCF_04193 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PIBGAFCF_04194 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PIBGAFCF_04195 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
PIBGAFCF_04196 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
PIBGAFCF_04197 2.29e-192 - - - S - - - membrane
PIBGAFCF_04198 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
PIBGAFCF_04199 0.0 - - - I - - - PLD-like domain
PIBGAFCF_04200 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
PIBGAFCF_04201 4.04e-103 - - - - - - - -
PIBGAFCF_04202 2.84e-123 tnpR - - L - - - resolvase
PIBGAFCF_04203 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
PIBGAFCF_04204 1.07e-57 - - - S - - - transposition, DNA-mediated
PIBGAFCF_04205 6.51e-150 - - - S - - - HTH-like domain
PIBGAFCF_04215 7.55e-59 orfX1 - - L - - - Transposase
PIBGAFCF_04216 5.6e-173 - - - L - - - Integrase core domain
PIBGAFCF_04223 1.1e-14 - - - - - - - -
PIBGAFCF_04224 1.67e-15 - - - S - - - Protein of unknown function (DUF2815)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)