ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NKFPMKOK_00001 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NKFPMKOK_00002 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NKFPMKOK_00003 1.72e-103 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NKFPMKOK_00004 1.42e-102 yuaE - - S - - - DinB superfamily
NKFPMKOK_00005 1.21e-134 - - - S - - - MOSC domain
NKFPMKOK_00006 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NKFPMKOK_00007 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NKFPMKOK_00008 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NKFPMKOK_00009 4.6e-119 yuaB - - - - - - -
NKFPMKOK_00010 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NKFPMKOK_00011 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKFPMKOK_00012 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKFPMKOK_00013 2.36e-47 - - - G - - - Cupin
NKFPMKOK_00014 2.17e-57 yjcN - - - - - - -
NKFPMKOK_00017 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NKFPMKOK_00018 7.36e-20 - - - - - - - -
NKFPMKOK_00020 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NKFPMKOK_00021 2.73e-248 yubA - - S - - - transporter activity
NKFPMKOK_00022 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NKFPMKOK_00023 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NKFPMKOK_00024 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NKFPMKOK_00025 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NKFPMKOK_00026 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NKFPMKOK_00027 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NKFPMKOK_00028 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NKFPMKOK_00029 1.82e-52 - - - - - - - -
NKFPMKOK_00030 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NKFPMKOK_00031 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKFPMKOK_00032 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NKFPMKOK_00033 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NKFPMKOK_00034 3.56e-22 - - - - - - - -
NKFPMKOK_00035 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
NKFPMKOK_00036 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NKFPMKOK_00037 4.57e-90 yugN - - S - - - YugN-like family
NKFPMKOK_00039 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NKFPMKOK_00040 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NKFPMKOK_00041 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NKFPMKOK_00042 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NKFPMKOK_00043 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NKFPMKOK_00044 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NKFPMKOK_00045 1.53e-108 alaR - - K - - - Transcriptional regulator
NKFPMKOK_00046 3.41e-192 yugF - - I - - - Hydrolase
NKFPMKOK_00047 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
NKFPMKOK_00048 1.89e-276 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NKFPMKOK_00049 1.57e-173 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00050 9.1e-83 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00051 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NKFPMKOK_00052 7.29e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NKFPMKOK_00053 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
NKFPMKOK_00054 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NKFPMKOK_00055 5.95e-92 yuxK - - S - - - protein conserved in bacteria
NKFPMKOK_00056 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
NKFPMKOK_00057 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NKFPMKOK_00058 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NKFPMKOK_00059 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NKFPMKOK_00060 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_00061 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKFPMKOK_00062 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKFPMKOK_00064 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NKFPMKOK_00065 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKFPMKOK_00066 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKFPMKOK_00067 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKFPMKOK_00068 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKFPMKOK_00069 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKFPMKOK_00070 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NKFPMKOK_00071 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NKFPMKOK_00072 3.29e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKFPMKOK_00073 1.19e-315 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00075 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NKFPMKOK_00076 1.87e-11 - - - S - - - DegQ (SacQ) family
NKFPMKOK_00077 1.59e-62 yuzC - - - - - - -
NKFPMKOK_00078 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NKFPMKOK_00079 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NKFPMKOK_00080 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NKFPMKOK_00081 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
NKFPMKOK_00082 1.1e-50 yueH - - S - - - YueH-like protein
NKFPMKOK_00083 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NKFPMKOK_00084 2.31e-232 yueF - - S - - - transporter activity
NKFPMKOK_00085 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
NKFPMKOK_00086 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NKFPMKOK_00087 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_00088 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
NKFPMKOK_00089 0.0 yueB - - S - - - type VII secretion protein EsaA
NKFPMKOK_00090 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NKFPMKOK_00091 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NKFPMKOK_00092 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NKFPMKOK_00093 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
NKFPMKOK_00094 1.66e-288 yukF - - QT - - - Transcriptional regulator
NKFPMKOK_00095 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NKFPMKOK_00096 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NKFPMKOK_00097 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NKFPMKOK_00098 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_00099 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NKFPMKOK_00100 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NKFPMKOK_00101 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NKFPMKOK_00102 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_00103 2.31e-198 eSD - - S ko:K07017 - ko00000 Putative esterase
NKFPMKOK_00104 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NKFPMKOK_00105 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NKFPMKOK_00106 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NKFPMKOK_00107 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NKFPMKOK_00108 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NKFPMKOK_00109 2.23e-149 yuiC - - S - - - protein conserved in bacteria
NKFPMKOK_00110 1.21e-45 yuiB - - S - - - Putative membrane protein
NKFPMKOK_00111 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NKFPMKOK_00112 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NKFPMKOK_00114 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NKFPMKOK_00115 1.57e-37 - - - - - - - -
NKFPMKOK_00116 1.09e-86 - - - CP - - - Membrane
NKFPMKOK_00117 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NKFPMKOK_00119 1.25e-42 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
NKFPMKOK_00121 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NKFPMKOK_00122 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_00123 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NKFPMKOK_00124 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NKFPMKOK_00125 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKFPMKOK_00126 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
NKFPMKOK_00127 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NKFPMKOK_00128 2.61e-70 yuzD - - S - - - protein conserved in bacteria
NKFPMKOK_00129 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NKFPMKOK_00130 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NKFPMKOK_00131 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NKFPMKOK_00132 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NKFPMKOK_00133 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NKFPMKOK_00134 5.56e-244 yutH - - S - - - Spore coat protein
NKFPMKOK_00135 1.07e-108 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NKFPMKOK_00136 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NKFPMKOK_00137 3e-93 yutE - - S - - - Protein of unknown function DUF86
NKFPMKOK_00138 3.71e-62 yutD - - S - - - protein conserved in bacteria
NKFPMKOK_00139 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NKFPMKOK_00140 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NKFPMKOK_00141 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NKFPMKOK_00142 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKFPMKOK_00143 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NKFPMKOK_00144 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
NKFPMKOK_00145 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
NKFPMKOK_00146 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NKFPMKOK_00147 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NKFPMKOK_00148 6.3e-86 - - - - - - - -
NKFPMKOK_00149 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00150 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NKFPMKOK_00151 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NKFPMKOK_00152 3.33e-209 bsn - - L - - - Ribonuclease
NKFPMKOK_00153 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_00154 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NKFPMKOK_00155 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NKFPMKOK_00156 3.4e-198 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NKFPMKOK_00157 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKFPMKOK_00158 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NKFPMKOK_00159 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NKFPMKOK_00160 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
NKFPMKOK_00162 1.34e-95 - - - - - - - -
NKFPMKOK_00166 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NKFPMKOK_00167 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NKFPMKOK_00168 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
NKFPMKOK_00169 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
NKFPMKOK_00170 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NKFPMKOK_00171 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NKFPMKOK_00172 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NKFPMKOK_00173 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKFPMKOK_00174 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NKFPMKOK_00175 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NKFPMKOK_00177 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NKFPMKOK_00178 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NKFPMKOK_00179 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NKFPMKOK_00180 1.24e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NKFPMKOK_00181 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
NKFPMKOK_00182 2.25e-70 yusE - - CO - - - Thioredoxin
NKFPMKOK_00183 5.93e-30 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NKFPMKOK_00184 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
NKFPMKOK_00185 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NKFPMKOK_00186 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NKFPMKOK_00187 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NKFPMKOK_00188 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NKFPMKOK_00189 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NKFPMKOK_00190 1.72e-10 - - - S - - - YuzL-like protein
NKFPMKOK_00191 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NKFPMKOK_00192 7.03e-53 - - - - - - - -
NKFPMKOK_00193 3.53e-69 yusN - - M - - - Coat F domain
NKFPMKOK_00194 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NKFPMKOK_00195 0.0 yusP - - P - - - Major facilitator superfamily
NKFPMKOK_00196 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
NKFPMKOK_00197 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_00198 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NKFPMKOK_00199 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
NKFPMKOK_00200 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NKFPMKOK_00201 2.79e-62 - - - S - - - YusW-like protein
NKFPMKOK_00202 1.59e-288 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NKFPMKOK_00203 1.86e-78 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NKFPMKOK_00204 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_00205 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NKFPMKOK_00206 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKFPMKOK_00207 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_00208 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00209 2.68e-32 - - - - - - - -
NKFPMKOK_00210 6.7e-196 yuxN - - K - - - Transcriptional regulator
NKFPMKOK_00211 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NKFPMKOK_00212 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
NKFPMKOK_00213 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NKFPMKOK_00214 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NKFPMKOK_00215 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NKFPMKOK_00216 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKFPMKOK_00217 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00218 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NKFPMKOK_00219 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NKFPMKOK_00220 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NKFPMKOK_00221 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NKFPMKOK_00222 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00223 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NKFPMKOK_00224 1.87e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NKFPMKOK_00225 1.64e-223 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_00226 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NKFPMKOK_00227 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_00228 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NKFPMKOK_00229 0.0 yvrG - - T - - - Histidine kinase
NKFPMKOK_00230 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_00231 1.14e-48 - - - - - - - -
NKFPMKOK_00232 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NKFPMKOK_00233 1.88e-21 - - - S - - - YvrJ protein family
NKFPMKOK_00234 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NKFPMKOK_00235 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
NKFPMKOK_00236 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NKFPMKOK_00237 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_00238 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_00239 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NKFPMKOK_00240 2.17e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NKFPMKOK_00241 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NKFPMKOK_00242 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NKFPMKOK_00243 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NKFPMKOK_00244 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NKFPMKOK_00245 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NKFPMKOK_00246 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NKFPMKOK_00247 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NKFPMKOK_00248 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NKFPMKOK_00249 2.17e-146 yfiK - - K - - - Regulator
NKFPMKOK_00250 3.01e-237 - - - T - - - Histidine kinase
NKFPMKOK_00251 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NKFPMKOK_00252 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NKFPMKOK_00253 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NKFPMKOK_00254 1.77e-200 yvgN - - S - - - reductase
NKFPMKOK_00255 1.55e-110 yvgO - - - - - - -
NKFPMKOK_00256 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NKFPMKOK_00257 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NKFPMKOK_00258 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NKFPMKOK_00259 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NKFPMKOK_00260 2.48e-96 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NKFPMKOK_00261 6.1e-128 yvgT - - S - - - membrane
NKFPMKOK_00262 5.24e-188 - - - S - - - Metallo-peptidase family M12
NKFPMKOK_00263 5.06e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NKFPMKOK_00264 2.51e-135 bdbD - - O - - - Thioredoxin
NKFPMKOK_00265 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NKFPMKOK_00266 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NKFPMKOK_00267 9.29e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
NKFPMKOK_00268 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NKFPMKOK_00269 4.69e-238 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NKFPMKOK_00270 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKFPMKOK_00271 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_00272 1.97e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NKFPMKOK_00273 7.09e-226 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_00274 1.18e-176 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NKFPMKOK_00275 5.33e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKFPMKOK_00276 1.35e-152 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKFPMKOK_00277 1.8e-181 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NKFPMKOK_00278 3.28e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NKFPMKOK_00279 5.25e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NKFPMKOK_00280 4.27e-201 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NKFPMKOK_00281 1.18e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_00282 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NKFPMKOK_00284 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NKFPMKOK_00285 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NKFPMKOK_00286 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NKFPMKOK_00287 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NKFPMKOK_00288 1.64e-47 yvzC - - K - - - transcriptional
NKFPMKOK_00289 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NKFPMKOK_00290 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NKFPMKOK_00291 1.17e-67 yvaP - - K - - - transcriptional
NKFPMKOK_00292 3.51e-308 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
NKFPMKOK_00293 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NKFPMKOK_00294 1.93e-167 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NKFPMKOK_00295 1.35e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NKFPMKOK_00296 1.73e-158 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_00297 4.05e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NKFPMKOK_00298 4.75e-215 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKFPMKOK_00299 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NKFPMKOK_00300 1.39e-259 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKFPMKOK_00301 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NKFPMKOK_00302 2.08e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NKFPMKOK_00303 6.03e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKFPMKOK_00304 3.12e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NKFPMKOK_00305 7.33e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKFPMKOK_00306 1.88e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NKFPMKOK_00307 7.35e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NKFPMKOK_00308 5.38e-142 yvbI - - M - - - Membrane
NKFPMKOK_00309 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NKFPMKOK_00311 1.24e-103 yvbK - - K - - - acetyltransferase
NKFPMKOK_00312 4.16e-260 - - - EGP - - - Major facilitator Superfamily
NKFPMKOK_00313 1.87e-219 - - - - - - - -
NKFPMKOK_00314 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
NKFPMKOK_00315 1.13e-182 - - - C - - - WbqC-like protein family
NKFPMKOK_00316 1.44e-178 - - - M - - - Protein involved in cellulose biosynthesis
NKFPMKOK_00317 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NKFPMKOK_00318 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
NKFPMKOK_00319 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NKFPMKOK_00320 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKFPMKOK_00321 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NKFPMKOK_00322 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NKFPMKOK_00323 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NKFPMKOK_00324 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NKFPMKOK_00325 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NKFPMKOK_00326 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKFPMKOK_00327 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKFPMKOK_00329 4.6e-272 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NKFPMKOK_00330 1.76e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NKFPMKOK_00331 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_00332 3.86e-18 yvbU - - K - - - Transcriptional regulator
NKFPMKOK_00333 2.18e-124 yvbU - - K - - - Transcriptional regulator
NKFPMKOK_00334 2.18e-195 yvbV - - EG - - - EamA-like transporter family
NKFPMKOK_00335 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_00337 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
NKFPMKOK_00338 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NKFPMKOK_00339 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NKFPMKOK_00340 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKFPMKOK_00341 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NKFPMKOK_00342 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKFPMKOK_00343 2.07e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKFPMKOK_00344 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NKFPMKOK_00345 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NKFPMKOK_00346 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NKFPMKOK_00347 4.01e-44 yvfG - - S - - - YvfG protein
NKFPMKOK_00348 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NKFPMKOK_00349 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NKFPMKOK_00350 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NKFPMKOK_00351 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKFPMKOK_00352 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_00353 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NKFPMKOK_00354 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NKFPMKOK_00355 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NKFPMKOK_00356 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NKFPMKOK_00357 1.13e-252 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NKFPMKOK_00358 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NKFPMKOK_00359 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NKFPMKOK_00360 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NKFPMKOK_00361 7.59e-147 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NKFPMKOK_00362 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NKFPMKOK_00363 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NKFPMKOK_00364 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NKFPMKOK_00366 8.3e-111 ywjB - - H - - - RibD C-terminal domain
NKFPMKOK_00367 4.2e-164 - - - CH - - - FAD binding domain
NKFPMKOK_00368 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
NKFPMKOK_00369 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
NKFPMKOK_00370 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKFPMKOK_00371 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NKFPMKOK_00372 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
NKFPMKOK_00373 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
NKFPMKOK_00374 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
NKFPMKOK_00375 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
NKFPMKOK_00376 2.67e-158 - - - I - - - Pfam Lipase (class 3)
NKFPMKOK_00377 2.88e-120 - - - I - - - Pfam Lipase (class 3)
NKFPMKOK_00378 3.08e-44 - - - - - - - -
NKFPMKOK_00380 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NKFPMKOK_00381 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NKFPMKOK_00382 2.68e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NKFPMKOK_00383 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NKFPMKOK_00384 1.4e-202 yraN - - K - - - Transcriptional regulator
NKFPMKOK_00385 3.16e-258 yraM - - S - - - PrpF protein
NKFPMKOK_00386 6.64e-313 - - - EGP - - - Sugar (and other) transporter
NKFPMKOK_00387 1.06e-110 - - - - - - - -
NKFPMKOK_00388 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NKFPMKOK_00389 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NKFPMKOK_00390 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NKFPMKOK_00391 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NKFPMKOK_00392 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKFPMKOK_00393 4.11e-100 - - - M - - - Ribonuclease
NKFPMKOK_00394 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NKFPMKOK_00395 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NKFPMKOK_00396 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NKFPMKOK_00397 3.01e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NKFPMKOK_00398 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NKFPMKOK_00399 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NKFPMKOK_00400 6.06e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NKFPMKOK_00401 7.8e-192 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NKFPMKOK_00402 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NKFPMKOK_00403 1.01e-231 sasA - - T - - - Histidine kinase
NKFPMKOK_00404 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_00405 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NKFPMKOK_00406 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NKFPMKOK_00407 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NKFPMKOK_00408 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NKFPMKOK_00409 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NKFPMKOK_00410 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NKFPMKOK_00411 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NKFPMKOK_00412 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NKFPMKOK_00413 9.79e-260 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NKFPMKOK_00414 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
NKFPMKOK_00415 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NKFPMKOK_00416 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NKFPMKOK_00417 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKFPMKOK_00418 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NKFPMKOK_00419 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NKFPMKOK_00420 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NKFPMKOK_00421 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NKFPMKOK_00422 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NKFPMKOK_00423 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NKFPMKOK_00424 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
NKFPMKOK_00425 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NKFPMKOK_00426 4.14e-214 yvlB - - S - - - Putative adhesin
NKFPMKOK_00427 1.79e-61 yvlA - - - - - - -
NKFPMKOK_00428 1.29e-40 yvkN - - - - - - -
NKFPMKOK_00429 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NKFPMKOK_00430 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NKFPMKOK_00431 2.59e-45 csbA - - S - - - protein conserved in bacteria
NKFPMKOK_00432 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NKFPMKOK_00433 1.12e-119 yvkB - - K - - - Transcriptional regulator
NKFPMKOK_00434 3.49e-290 yvkA - - P - - - -transporter
NKFPMKOK_00437 1.39e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKFPMKOK_00438 5.83e-72 swrA - - S - - - Swarming motility protein
NKFPMKOK_00439 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NKFPMKOK_00440 1.35e-271 ywoF - - P - - - Right handed beta helix region
NKFPMKOK_00441 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NKFPMKOK_00442 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NKFPMKOK_00443 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NKFPMKOK_00444 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_00445 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NKFPMKOK_00446 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NKFPMKOK_00447 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NKFPMKOK_00448 1.92e-89 - - - - - - - -
NKFPMKOK_00449 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NKFPMKOK_00450 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NKFPMKOK_00451 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NKFPMKOK_00452 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKFPMKOK_00453 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NKFPMKOK_00454 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NKFPMKOK_00455 1.27e-104 yviE - - - - - - -
NKFPMKOK_00456 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NKFPMKOK_00457 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NKFPMKOK_00458 1.43e-101 yvyG - - NOU - - - FlgN protein
NKFPMKOK_00459 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NKFPMKOK_00460 6.15e-95 yvyF - - S - - - flagellar protein
NKFPMKOK_00461 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NKFPMKOK_00462 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NKFPMKOK_00463 8.75e-315 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NKFPMKOK_00464 3.16e-197 degV - - S - - - protein conserved in bacteria
NKFPMKOK_00465 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKFPMKOK_00466 3.83e-244 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NKFPMKOK_00467 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NKFPMKOK_00468 9.24e-234 yvhJ - - K - - - Transcriptional regulator
NKFPMKOK_00469 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NKFPMKOK_00470 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NKFPMKOK_00471 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NKFPMKOK_00472 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NKFPMKOK_00473 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NKFPMKOK_00474 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKFPMKOK_00475 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NKFPMKOK_00476 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_00477 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKFPMKOK_00478 5.41e-269 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NKFPMKOK_00479 0.0 lytB - - D - - - Stage II sporulation protein
NKFPMKOK_00480 1.99e-39 - - - - - - - -
NKFPMKOK_00481 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NKFPMKOK_00482 8.48e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NKFPMKOK_00483 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NKFPMKOK_00484 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NKFPMKOK_00485 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NKFPMKOK_00486 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKFPMKOK_00487 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
NKFPMKOK_00488 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NKFPMKOK_00489 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NKFPMKOK_00490 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKFPMKOK_00491 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKFPMKOK_00492 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKFPMKOK_00493 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NKFPMKOK_00494 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NKFPMKOK_00495 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NKFPMKOK_00496 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
NKFPMKOK_00497 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NKFPMKOK_00498 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
NKFPMKOK_00499 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NKFPMKOK_00500 1.4e-60 yttA - - S - - - Pfam Transposase IS66
NKFPMKOK_00501 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKFPMKOK_00502 1.16e-28 ywtC - - - - - - -
NKFPMKOK_00503 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NKFPMKOK_00504 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NKFPMKOK_00505 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NKFPMKOK_00506 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NKFPMKOK_00507 6.95e-228 - - - E - - - Spore germination protein
NKFPMKOK_00508 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NKFPMKOK_00509 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
NKFPMKOK_00510 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NKFPMKOK_00511 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NKFPMKOK_00512 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NKFPMKOK_00513 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NKFPMKOK_00514 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NKFPMKOK_00515 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NKFPMKOK_00516 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
NKFPMKOK_00517 2.39e-115 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NKFPMKOK_00518 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NKFPMKOK_00519 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NKFPMKOK_00520 6.98e-211 alsR - - K - - - LysR substrate binding domain
NKFPMKOK_00521 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKFPMKOK_00522 8.96e-150 ywrJ - - - - - - -
NKFPMKOK_00523 4.38e-157 cotB - - - ko:K06325 - ko00000 -
NKFPMKOK_00524 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
NKFPMKOK_00525 9.99e-10 - - - - - - - -
NKFPMKOK_00526 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NKFPMKOK_00528 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NKFPMKOK_00529 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NKFPMKOK_00530 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NKFPMKOK_00531 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NKFPMKOK_00532 1.29e-130 - - - - - - - -
NKFPMKOK_00533 7.15e-83 - - - - - - - -
NKFPMKOK_00534 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
NKFPMKOK_00535 1.92e-25 - - - - - - - -
NKFPMKOK_00536 2.19e-75 - - - S - - - SUKH-4 immunity protein
NKFPMKOK_00537 2.53e-287 ywqJ - - S - - - Pre-toxin TG
NKFPMKOK_00538 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
NKFPMKOK_00540 3.03e-183 ywqG - - S - - - Domain of unknown function (DUF1963)
NKFPMKOK_00541 9.97e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKFPMKOK_00542 4.63e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NKFPMKOK_00543 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NKFPMKOK_00544 8.45e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NKFPMKOK_00545 3e-22 - - - - - - - -
NKFPMKOK_00546 0.0 ywqB - - S - - - SWIM zinc finger
NKFPMKOK_00547 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKFPMKOK_00548 1.28e-193 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NKFPMKOK_00549 2.2e-177 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
NKFPMKOK_00550 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NKFPMKOK_00551 1.83e-74 ywpG - - - - - - -
NKFPMKOK_00552 1.79e-89 ywpF - - S - - - YwpF-like protein
NKFPMKOK_00553 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NKFPMKOK_00554 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NKFPMKOK_00555 4.41e-247 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NKFPMKOK_00556 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NKFPMKOK_00557 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NKFPMKOK_00558 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NKFPMKOK_00559 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NKFPMKOK_00560 5.3e-93 ywoH - - K - - - transcriptional
NKFPMKOK_00561 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00562 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NKFPMKOK_00563 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
NKFPMKOK_00564 2.1e-128 yjgF - - Q - - - Isochorismatase family
NKFPMKOK_00565 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NKFPMKOK_00566 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NKFPMKOK_00567 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NKFPMKOK_00568 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NKFPMKOK_00569 3.41e-88 ywnJ - - S - - - VanZ like family
NKFPMKOK_00570 1.67e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NKFPMKOK_00571 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NKFPMKOK_00573 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
NKFPMKOK_00574 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKFPMKOK_00575 1.12e-21 yqgA - - - - - - -
NKFPMKOK_00576 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
NKFPMKOK_00577 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NKFPMKOK_00578 3.09e-88 ywnA - - K - - - Transcriptional regulator
NKFPMKOK_00579 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NKFPMKOK_00580 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NKFPMKOK_00581 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NKFPMKOK_00582 2.21e-15 csbD - - K - - - CsbD-like
NKFPMKOK_00583 1.01e-105 ywmF - - S - - - Peptidase M50
NKFPMKOK_00584 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NKFPMKOK_00585 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NKFPMKOK_00586 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NKFPMKOK_00588 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NKFPMKOK_00589 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NKFPMKOK_00590 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NKFPMKOK_00591 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKFPMKOK_00592 2.11e-168 ywmB - - S - - - TATA-box binding
NKFPMKOK_00593 1.85e-44 ywzB - - S - - - membrane
NKFPMKOK_00594 1.98e-115 ywmA - - - - - - -
NKFPMKOK_00595 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NKFPMKOK_00596 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKFPMKOK_00597 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKFPMKOK_00598 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKFPMKOK_00599 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKFPMKOK_00600 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NKFPMKOK_00601 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKFPMKOK_00602 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NKFPMKOK_00603 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NKFPMKOK_00604 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKFPMKOK_00605 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKFPMKOK_00606 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
NKFPMKOK_00607 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NKFPMKOK_00608 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKFPMKOK_00609 1.53e-115 mntP - - P - - - Probably functions as a manganese efflux pump
NKFPMKOK_00610 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NKFPMKOK_00611 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NKFPMKOK_00612 1.73e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NKFPMKOK_00613 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NKFPMKOK_00615 8.34e-195 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NKFPMKOK_00616 2.06e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKFPMKOK_00617 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_00618 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NKFPMKOK_00619 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NKFPMKOK_00620 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NKFPMKOK_00621 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NKFPMKOK_00622 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NKFPMKOK_00623 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NKFPMKOK_00624 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NKFPMKOK_00625 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKFPMKOK_00626 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NKFPMKOK_00627 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NKFPMKOK_00628 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NKFPMKOK_00629 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
NKFPMKOK_00630 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NKFPMKOK_00631 1.32e-72 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NKFPMKOK_00632 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NKFPMKOK_00633 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NKFPMKOK_00634 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NKFPMKOK_00635 3.23e-58 ywjC - - - - - - -
NKFPMKOK_00636 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NKFPMKOK_00637 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKFPMKOK_00638 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NKFPMKOK_00639 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NKFPMKOK_00640 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NKFPMKOK_00641 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKFPMKOK_00642 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NKFPMKOK_00643 8.44e-99 ywiC - - S - - - YwiC-like protein
NKFPMKOK_00644 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NKFPMKOK_00645 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NKFPMKOK_00646 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NKFPMKOK_00647 4.46e-94 ywiB - - S - - - protein conserved in bacteria
NKFPMKOK_00649 1.55e-248 ywhL - - CO - - - amine dehydrogenase activity
NKFPMKOK_00650 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NKFPMKOK_00652 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NKFPMKOK_00653 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NKFPMKOK_00654 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKFPMKOK_00655 1.96e-93 - - - - - - - -
NKFPMKOK_00656 2.07e-116 ywhD - - S - - - YwhD family
NKFPMKOK_00657 1.29e-151 ywhC - - S - - - Peptidase family M50
NKFPMKOK_00658 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NKFPMKOK_00659 3.29e-90 ywhA - - K - - - Transcriptional regulator
NKFPMKOK_00660 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
NKFPMKOK_00661 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
NKFPMKOK_00662 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NKFPMKOK_00663 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NKFPMKOK_00664 3.27e-136 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NKFPMKOK_00665 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
NKFPMKOK_00666 2.51e-109 - - - S - - - membrane
NKFPMKOK_00667 1.93e-194 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_00668 2.13e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
NKFPMKOK_00671 1.87e-209 - - - - - - - -
NKFPMKOK_00673 8.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NKFPMKOK_00674 1.33e-199 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_00675 9.29e-207 - - - S - - - Conserved hypothetical protein 698
NKFPMKOK_00676 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NKFPMKOK_00677 6.64e-185 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NKFPMKOK_00678 2.37e-20 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NKFPMKOK_00680 2.12e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NKFPMKOK_00681 1.6e-290 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NKFPMKOK_00682 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NKFPMKOK_00683 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NKFPMKOK_00684 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_00685 4.67e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NKFPMKOK_00686 4.49e-143 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NKFPMKOK_00687 1.14e-276 ywfA - - EGP - - - -transporter
NKFPMKOK_00688 9.06e-238 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NKFPMKOK_00689 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NKFPMKOK_00690 0.0 rocB - - E - - - arginine degradation protein
NKFPMKOK_00691 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKFPMKOK_00692 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NKFPMKOK_00693 4.02e-80 - - - - - - - -
NKFPMKOK_00694 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NKFPMKOK_00695 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NKFPMKOK_00696 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NKFPMKOK_00697 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKFPMKOK_00698 9.02e-214 spsG - - M - - - Spore Coat
NKFPMKOK_00699 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
NKFPMKOK_00700 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NKFPMKOK_00701 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NKFPMKOK_00702 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NKFPMKOK_00703 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NKFPMKOK_00704 4.13e-180 spsA - - M - - - Spore Coat
NKFPMKOK_00705 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NKFPMKOK_00706 4.39e-76 ywdK - - S - - - small membrane protein
NKFPMKOK_00707 3.47e-287 ywdJ - - F - - - Xanthine uracil
NKFPMKOK_00708 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
NKFPMKOK_00709 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NKFPMKOK_00710 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
NKFPMKOK_00712 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NKFPMKOK_00713 6.09e-27 ywdA - - - - - - -
NKFPMKOK_00714 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NKFPMKOK_00715 4.52e-316 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00716 6.12e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NKFPMKOK_00718 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKFPMKOK_00719 1.83e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_00720 1.26e-150 - - - K - - - WYL domain
NKFPMKOK_00721 8.59e-162 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_00722 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
NKFPMKOK_00723 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
NKFPMKOK_00724 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NKFPMKOK_00725 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NKFPMKOK_00726 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NKFPMKOK_00727 1.5e-41 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NKFPMKOK_00728 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NKFPMKOK_00729 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NKFPMKOK_00730 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKFPMKOK_00731 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NKFPMKOK_00732 5.74e-48 ydaS - - S - - - membrane
NKFPMKOK_00733 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NKFPMKOK_00734 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKFPMKOK_00735 7.8e-78 gtcA - - S - - - GtrA-like protein
NKFPMKOK_00736 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NKFPMKOK_00738 6.64e-162 - - - H - - - Methionine biosynthesis protein MetW
NKFPMKOK_00739 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
NKFPMKOK_00740 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NKFPMKOK_00741 2.81e-296 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NKFPMKOK_00742 5.83e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NKFPMKOK_00743 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NKFPMKOK_00744 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NKFPMKOK_00745 2.45e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NKFPMKOK_00746 2.29e-200 ywbI - - K - - - Transcriptional regulator
NKFPMKOK_00747 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NKFPMKOK_00748 6.2e-142 ywbG - - M - - - effector of murein hydrolase
NKFPMKOK_00749 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NKFPMKOK_00750 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NKFPMKOK_00751 1.62e-199 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NKFPMKOK_00752 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NKFPMKOK_00753 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NKFPMKOK_00754 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKFPMKOK_00755 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKFPMKOK_00756 2.87e-205 gspA - - M - - - General stress
NKFPMKOK_00758 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NKFPMKOK_00759 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NKFPMKOK_00760 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NKFPMKOK_00761 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_00762 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NKFPMKOK_00763 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_00764 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NKFPMKOK_00765 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NKFPMKOK_00766 4.7e-316 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKFPMKOK_00767 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00768 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKFPMKOK_00769 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NKFPMKOK_00770 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NKFPMKOK_00771 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NKFPMKOK_00772 7.43e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_00773 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_00774 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NKFPMKOK_00775 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NKFPMKOK_00776 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKFPMKOK_00777 3.25e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00778 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00779 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKFPMKOK_00780 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKFPMKOK_00781 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NKFPMKOK_00782 1.23e-226 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKFPMKOK_00783 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NKFPMKOK_00784 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NKFPMKOK_00785 1.26e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NKFPMKOK_00786 2.06e-313 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NKFPMKOK_00787 8.69e-192 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NKFPMKOK_00788 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NKFPMKOK_00789 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NKFPMKOK_00790 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NKFPMKOK_00791 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NKFPMKOK_00792 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
NKFPMKOK_00793 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
NKFPMKOK_00794 1.45e-258 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_00795 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NKFPMKOK_00796 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKFPMKOK_00798 5.75e-115 yxkC - - S - - - Domain of unknown function (DUF4352)
NKFPMKOK_00799 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NKFPMKOK_00800 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NKFPMKOK_00803 3.81e-105 yxjI - - S - - - LURP-one-related
NKFPMKOK_00804 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NKFPMKOK_00805 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NKFPMKOK_00806 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKFPMKOK_00807 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
NKFPMKOK_00808 3.23e-60 yxiS - - - - - - -
NKFPMKOK_00809 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
NKFPMKOK_00810 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NKFPMKOK_00811 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NKFPMKOK_00812 9.73e-176 bglS - - M - - - licheninase activity
NKFPMKOK_00813 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NKFPMKOK_00814 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NKFPMKOK_00815 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NKFPMKOK_00817 9.75e-27 - - - - - - - -
NKFPMKOK_00819 2.79e-140 - - - - - - - -
NKFPMKOK_00820 4.23e-103 - - - - - - - -
NKFPMKOK_00821 2.91e-85 yxiG - - - - - - -
NKFPMKOK_00822 9.79e-75 yxxG - - - - - - -
NKFPMKOK_00824 1.95e-250 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NKFPMKOK_00825 7.42e-202 yxxF - - EG - - - EamA-like transporter family
NKFPMKOK_00826 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NKFPMKOK_00827 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKFPMKOK_00828 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00829 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NKFPMKOK_00830 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NKFPMKOK_00831 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NKFPMKOK_00832 0.0 - - - L - - - Z1 domain
NKFPMKOK_00833 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
NKFPMKOK_00834 1.01e-243 - - - S - - - AIPR protein
NKFPMKOK_00835 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NKFPMKOK_00836 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NKFPMKOK_00837 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NKFPMKOK_00838 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NKFPMKOK_00839 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NKFPMKOK_00840 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NKFPMKOK_00841 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NKFPMKOK_00842 2.59e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NKFPMKOK_00843 1.35e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKFPMKOK_00844 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NKFPMKOK_00845 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKFPMKOK_00846 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
NKFPMKOK_00849 9.45e-26 yxeE - - - - - - -
NKFPMKOK_00851 9.67e-33 yxeD - - - - - - -
NKFPMKOK_00852 4.86e-47 - - - - - - - -
NKFPMKOK_00853 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NKFPMKOK_00854 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
NKFPMKOK_00855 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NKFPMKOK_00856 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_00857 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00858 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_00859 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NKFPMKOK_00860 6.65e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NKFPMKOK_00861 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NKFPMKOK_00862 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NKFPMKOK_00863 2.76e-289 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NKFPMKOK_00864 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NKFPMKOK_00865 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NKFPMKOK_00866 4.09e-224 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NKFPMKOK_00867 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NKFPMKOK_00868 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKFPMKOK_00869 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NKFPMKOK_00870 1.72e-215 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NKFPMKOK_00871 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NKFPMKOK_00872 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NKFPMKOK_00873 1.56e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NKFPMKOK_00874 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKFPMKOK_00875 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_00876 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NKFPMKOK_00877 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NKFPMKOK_00878 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NKFPMKOK_00879 2.12e-185 yxaL - - S - - - PQQ-like domain
NKFPMKOK_00880 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
NKFPMKOK_00881 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NKFPMKOK_00882 1.16e-250 - - - EGP - - - Major Facilitator Superfamily
NKFPMKOK_00883 2.58e-86 yxaI - - S - - - membrane protein domain
NKFPMKOK_00884 2.86e-83 - - - E - - - Ring-cleavage extradiol dioxygenase
NKFPMKOK_00885 5.77e-56 - - - E - - - Ring-cleavage extradiol dioxygenase
NKFPMKOK_00886 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NKFPMKOK_00887 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NKFPMKOK_00888 9.59e-234 mrjp - - G - - - Major royal jelly protein
NKFPMKOK_00889 1.26e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_00890 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
NKFPMKOK_00891 2.97e-95 - - - K - - - Integron-associated effector binding protein
NKFPMKOK_00892 6.31e-98 yjhE - - S - - - Phage tail protein
NKFPMKOK_00893 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
NKFPMKOK_00894 1.1e-73 ygzB - - S - - - UPF0295 protein
NKFPMKOK_00895 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NKFPMKOK_00896 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NKFPMKOK_00897 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NKFPMKOK_00898 1.76e-237 ygaE - - S - - - Membrane
NKFPMKOK_00899 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NKFPMKOK_00900 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NKFPMKOK_00901 1.4e-49 ygaB - - S - - - YgaB-like protein
NKFPMKOK_00902 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NKFPMKOK_00903 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_00904 1.47e-49 yfhS - - - - - - -
NKFPMKOK_00905 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NKFPMKOK_00906 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NKFPMKOK_00907 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NKFPMKOK_00908 1.29e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NKFPMKOK_00909 5.37e-156 - - - S - - - Alpha/beta hydrolase family
NKFPMKOK_00910 1.7e-47 yfhL - - S - - - SdpI/YhfL protein family
NKFPMKOK_00911 2.3e-112 yfhK - - T - - - Bacterial SH3 domain homologues
NKFPMKOK_00912 4.27e-58 yfhJ - - S - - - WVELL protein
NKFPMKOK_00913 6.62e-203 mpr - - M - - - Belongs to the peptidase S1B family
NKFPMKOK_00915 6.7e-231 yfhI - - EGP - - - -transporter
NKFPMKOK_00916 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
NKFPMKOK_00917 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NKFPMKOK_00918 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NKFPMKOK_00920 6.01e-33 yfhD - - S - - - YfhD-like protein
NKFPMKOK_00921 3.09e-133 yfhC - - C - - - nitroreductase
NKFPMKOK_00922 1.27e-193 yfhB - - S - - - PhzF family
NKFPMKOK_00923 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NKFPMKOK_00924 2.11e-103 yfiV - - K - - - transcriptional
NKFPMKOK_00925 0.0 yfiU - - EGP - - - the major facilitator superfamily
NKFPMKOK_00926 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NKFPMKOK_00927 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NKFPMKOK_00928 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NKFPMKOK_00929 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NKFPMKOK_00930 1e-119 padR - - K - - - transcriptional
NKFPMKOK_00931 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKFPMKOK_00932 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKFPMKOK_00933 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NKFPMKOK_00934 7.86e-82 yfiD3 - - S - - - DoxX
NKFPMKOK_00935 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NKFPMKOK_00936 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NKFPMKOK_00937 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
NKFPMKOK_00938 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00939 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NKFPMKOK_00940 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKFPMKOK_00941 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NKFPMKOK_00942 1.29e-40 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NKFPMKOK_00943 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NKFPMKOK_00944 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKFPMKOK_00945 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKFPMKOK_00946 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKFPMKOK_00947 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKFPMKOK_00948 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
NKFPMKOK_00949 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKFPMKOK_00950 1.83e-60 - - - S - - - YfzA-like protein
NKFPMKOK_00958 0.0 - - - KLT - - - Protein kinase domain
NKFPMKOK_00959 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NKFPMKOK_00960 3.05e-93 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
NKFPMKOK_00961 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKFPMKOK_00962 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NKFPMKOK_00963 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NKFPMKOK_00965 4.07e-86 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NKFPMKOK_00966 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NKFPMKOK_00967 7.99e-37 yfjT - - - - - - -
NKFPMKOK_00968 9.38e-279 yfkA - - S - - - YfkB-like domain
NKFPMKOK_00969 5.34e-182 yfkC - - M - - - Mechanosensitive ion channel
NKFPMKOK_00970 4.99e-180 yfkD - - S - - - YfkD-like protein
NKFPMKOK_00971 5.21e-233 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NKFPMKOK_00972 1.55e-273 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00973 8.85e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NKFPMKOK_00974 2.71e-63 yfkI - - S - - - gas vesicle protein
NKFPMKOK_00975 1.38e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKFPMKOK_00976 1.28e-39 yfkK - - S - - - Belongs to the UPF0435 family
NKFPMKOK_00977 3.66e-23 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00978 1.42e-199 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_00979 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NKFPMKOK_00980 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKFPMKOK_00981 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NKFPMKOK_00982 4.01e-115 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NKFPMKOK_00983 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NKFPMKOK_00984 5.49e-235 yibE - - S - - - YibE/F-like protein
NKFPMKOK_00985 8.73e-160 yibF - - S - - - YibE/F-like protein
NKFPMKOK_00986 1.34e-154 frp - - C - - - nitroreductase
NKFPMKOK_00987 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NKFPMKOK_00988 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKFPMKOK_00989 1.5e-311 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_00990 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
NKFPMKOK_00991 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
NKFPMKOK_00992 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NKFPMKOK_00993 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NKFPMKOK_00994 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NKFPMKOK_00995 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NKFPMKOK_00996 3.41e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NKFPMKOK_00997 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NKFPMKOK_00998 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
NKFPMKOK_00999 5.69e-26 yflI - - - - - - -
NKFPMKOK_01000 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
NKFPMKOK_01001 1.9e-153 yflK - - S - - - protein conserved in bacteria
NKFPMKOK_01002 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NKFPMKOK_01003 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NKFPMKOK_01004 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NKFPMKOK_01005 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NKFPMKOK_01006 5.53e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NKFPMKOK_01007 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NKFPMKOK_01008 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NKFPMKOK_01009 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NKFPMKOK_01010 0.0 - - - M - - - cell wall anchor domain
NKFPMKOK_01011 0.0 - - - M - - - cell wall anchor domain
NKFPMKOK_01012 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
NKFPMKOK_01013 0.0 ywpD - - T - - - Histidine kinase
NKFPMKOK_01014 3.08e-92 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
NKFPMKOK_01015 2.81e-67 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
NKFPMKOK_01017 1.45e-43 - - - Q - - - Collagen triple helix repeat (20 copies)
NKFPMKOK_01019 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NKFPMKOK_01020 5.26e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NKFPMKOK_01021 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
NKFPMKOK_01022 2.56e-28 - - - S - - - Protein of unknown function (DUF3212)
NKFPMKOK_01023 1.41e-99 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NKFPMKOK_01024 3.25e-64 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NKFPMKOK_01025 4.02e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NKFPMKOK_01026 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKFPMKOK_01027 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NKFPMKOK_01028 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NKFPMKOK_01029 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKFPMKOK_01030 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NKFPMKOK_01031 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NKFPMKOK_01032 3.69e-165 yfmS - - NT - - - chemotaxis protein
NKFPMKOK_01033 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKFPMKOK_01034 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
NKFPMKOK_01035 4.78e-272 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_01036 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NKFPMKOK_01037 3.25e-272 yfnE - - S - - - Glycosyltransferase like family 2
NKFPMKOK_01038 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NKFPMKOK_01039 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NKFPMKOK_01040 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NKFPMKOK_01041 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NKFPMKOK_01043 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NKFPMKOK_01044 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NKFPMKOK_01045 3.35e-246 yetM - - CH - - - FAD binding domain
NKFPMKOK_01046 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_01047 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NKFPMKOK_01048 2.59e-73 - - - H - - - riboflavin kinase activity
NKFPMKOK_01049 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
NKFPMKOK_01050 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKFPMKOK_01051 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_01052 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NKFPMKOK_01053 1.26e-147 yetF - - S - - - membrane
NKFPMKOK_01055 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
NKFPMKOK_01056 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NKFPMKOK_01057 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
NKFPMKOK_01058 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NKFPMKOK_01059 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NKFPMKOK_01061 4.43e-162 yeeN - - K - - - transcriptional regulatory protein
NKFPMKOK_01062 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
NKFPMKOK_01063 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NKFPMKOK_01064 2.48e-66 - - - S - - - Protein of unknown function, DUF600
NKFPMKOK_01065 2.35e-73 - - - S - - - Protein of unknown function, DUF600
NKFPMKOK_01066 5.92e-51 - - - S - - - Protein of unknown function, DUF600
NKFPMKOK_01067 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NKFPMKOK_01068 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NKFPMKOK_01069 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NKFPMKOK_01070 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKFPMKOK_01071 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKFPMKOK_01072 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKFPMKOK_01073 1.01e-189 yerO - - K - - - Transcriptional regulator
NKFPMKOK_01074 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKFPMKOK_01075 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NKFPMKOK_01076 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKFPMKOK_01077 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKFPMKOK_01078 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NKFPMKOK_01079 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NKFPMKOK_01080 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NKFPMKOK_01081 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NKFPMKOK_01082 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NKFPMKOK_01083 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NKFPMKOK_01084 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NKFPMKOK_01085 2.03e-67 yerC - - S - - - protein conserved in bacteria
NKFPMKOK_01086 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NKFPMKOK_01087 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NKFPMKOK_01088 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
NKFPMKOK_01089 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NKFPMKOK_01090 4.48e-81 - - - K - - - helix_turn_helix ASNC type
NKFPMKOK_01091 2.12e-293 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NKFPMKOK_01092 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NKFPMKOK_01093 1.16e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKFPMKOK_01094 2.08e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NKFPMKOK_01095 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NKFPMKOK_01096 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKFPMKOK_01097 4.32e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKFPMKOK_01098 2.57e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKFPMKOK_01099 3.8e-163 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NKFPMKOK_01100 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NKFPMKOK_01101 1.15e-280 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NKFPMKOK_01102 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKFPMKOK_01103 1.88e-39 yebG - - S - - - NETI protein
NKFPMKOK_01104 1.08e-119 yebE - - S - - - UPF0316 protein
NKFPMKOK_01106 4.87e-165 yebC - - M - - - Membrane
NKFPMKOK_01107 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NKFPMKOK_01108 0.0 - - - S - - - Domain of unknown function (DUF4179)
NKFPMKOK_01109 3.26e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_01110 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NKFPMKOK_01111 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NKFPMKOK_01112 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NKFPMKOK_01113 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NKFPMKOK_01114 7.59e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKFPMKOK_01115 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_01116 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NKFPMKOK_01117 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
NKFPMKOK_01119 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NKFPMKOK_01120 7.91e-83 ydjM - - M - - - Lytic transglycolase
NKFPMKOK_01121 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NKFPMKOK_01122 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_01123 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
NKFPMKOK_01124 0.0 oatA - - I - - - Acyltransferase family
NKFPMKOK_01125 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NKFPMKOK_01126 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NKFPMKOK_01127 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKFPMKOK_01128 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NKFPMKOK_01129 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
NKFPMKOK_01130 4.48e-211 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NKFPMKOK_01131 9.02e-311 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NKFPMKOK_01132 9.34e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NKFPMKOK_01133 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NKFPMKOK_01134 2.21e-81 - - - - - - - -
NKFPMKOK_01136 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
NKFPMKOK_01139 5.73e-155 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NKFPMKOK_01140 2.07e-37 xhlB - - S - - - SPP1 phage holin
NKFPMKOK_01141 1.19e-40 xhlA - - S - - - Haemolysin XhlA
NKFPMKOK_01145 2.51e-246 - - - L - - - Phage minor structural protein
NKFPMKOK_01148 8.44e-187 - - - - - - - -
NKFPMKOK_01150 1.3e-43 - - - S - - - Phage tail tube protein
NKFPMKOK_01151 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
NKFPMKOK_01152 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NKFPMKOK_01153 7.37e-38 - - - S - - - Phage head-tail joining protein
NKFPMKOK_01154 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
NKFPMKOK_01157 1.85e-61 - - - S - - - viral capsid
NKFPMKOK_01158 3.82e-56 - - - S - - - Phage minor structural protein GP20
NKFPMKOK_01160 1.53e-116 - - - S - - - Phage Mu protein F like protein
NKFPMKOK_01161 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
NKFPMKOK_01162 9.66e-225 - - - S - - - Pfam:Terminase_3C
NKFPMKOK_01163 7.49e-103 yqaS - - L - - - DNA packaging
NKFPMKOK_01166 1.74e-17 - - - K - - - Transcriptional regulator
NKFPMKOK_01168 5.88e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKFPMKOK_01169 1.76e-22 - - - V - - - VanZ like family
NKFPMKOK_01171 3.27e-63 - - - - - - - -
NKFPMKOK_01176 2.62e-08 - - - S - - - YopX protein
NKFPMKOK_01179 2.08e-54 - - - S - - - dUTPase
NKFPMKOK_01181 4.72e-217 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NKFPMKOK_01184 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
NKFPMKOK_01185 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
NKFPMKOK_01186 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
NKFPMKOK_01187 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
NKFPMKOK_01188 1.06e-42 - - - - - - - -
NKFPMKOK_01189 2.31e-90 - - - S - - - Bacterial EndoU nuclease
NKFPMKOK_01190 2.03e-64 - - - - - - - -
NKFPMKOK_01192 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NKFPMKOK_01193 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NKFPMKOK_01194 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NKFPMKOK_01195 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NKFPMKOK_01196 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKFPMKOK_01197 1.19e-45 - - - K - - - SpoVT / AbrB like domain
NKFPMKOK_01198 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NKFPMKOK_01199 2e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
NKFPMKOK_01200 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
NKFPMKOK_01201 1.62e-44 - - - - - - - -
NKFPMKOK_01202 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NKFPMKOK_01203 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
NKFPMKOK_01204 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NKFPMKOK_01207 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
NKFPMKOK_01208 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NKFPMKOK_01209 1.02e-36 cotW - - - ko:K06341 - ko00000 -
NKFPMKOK_01210 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NKFPMKOK_01211 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NKFPMKOK_01212 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NKFPMKOK_01213 2.47e-100 yjbX - - S - - - Spore coat protein
NKFPMKOK_01214 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NKFPMKOK_01215 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NKFPMKOK_01216 1.17e-226 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKFPMKOK_01217 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NKFPMKOK_01218 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
NKFPMKOK_01219 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NKFPMKOK_01220 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NKFPMKOK_01221 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NKFPMKOK_01222 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NKFPMKOK_01223 2.39e-102 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NKFPMKOK_01224 5.9e-61 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NKFPMKOK_01225 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NKFPMKOK_01226 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKFPMKOK_01227 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NKFPMKOK_01228 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
NKFPMKOK_01229 8.1e-118 yjbK - - S - - - protein conserved in bacteria
NKFPMKOK_01230 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKFPMKOK_01231 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NKFPMKOK_01232 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NKFPMKOK_01233 3.14e-27 - - - - - - - -
NKFPMKOK_01234 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NKFPMKOK_01235 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
NKFPMKOK_01236 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKFPMKOK_01237 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
NKFPMKOK_01238 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NKFPMKOK_01239 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKFPMKOK_01240 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
NKFPMKOK_01241 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01242 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01243 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_01244 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_01245 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NKFPMKOK_01246 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NKFPMKOK_01247 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
NKFPMKOK_01248 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_01249 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_01250 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NKFPMKOK_01251 4.48e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01252 1.81e-226 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01253 2.47e-179 yjaZ - - O - - - Zn-dependent protease
NKFPMKOK_01254 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKFPMKOK_01255 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKFPMKOK_01256 1.46e-37 yjzB - - - - - - -
NKFPMKOK_01257 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NKFPMKOK_01258 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NKFPMKOK_01259 7.04e-127 yjaV - - - - - - -
NKFPMKOK_01260 6.59e-171 yjaU - - I - - - carboxylic ester hydrolase activity
NKFPMKOK_01261 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
NKFPMKOK_01262 2.07e-38 yjzC - - S - - - YjzC-like protein
NKFPMKOK_01263 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKFPMKOK_01264 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NKFPMKOK_01265 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NKFPMKOK_01266 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NKFPMKOK_01267 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NKFPMKOK_01268 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NKFPMKOK_01269 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NKFPMKOK_01270 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
NKFPMKOK_01271 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NKFPMKOK_01272 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NKFPMKOK_01273 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NKFPMKOK_01274 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NKFPMKOK_01275 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NKFPMKOK_01276 1.49e-11 - - - - - - - -
NKFPMKOK_01277 1.23e-35 - - - S - - - Protein of unknown function (DUF3813)
NKFPMKOK_01278 3.05e-104 ipi - - S - - - Intracellular proteinase inhibitor
NKFPMKOK_01279 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_01280 8.05e-196 yitS - - S - - - protein conserved in bacteria
NKFPMKOK_01281 4.22e-293 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NKFPMKOK_01282 1.86e-87 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NKFPMKOK_01283 4.19e-158 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NKFPMKOK_01284 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
NKFPMKOK_01285 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NKFPMKOK_01286 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NKFPMKOK_01287 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NKFPMKOK_01288 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
NKFPMKOK_01289 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
NKFPMKOK_01290 1.72e-232 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKFPMKOK_01291 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NKFPMKOK_01292 3.26e-100 yisT - - S - - - DinB family
NKFPMKOK_01293 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NKFPMKOK_01294 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NKFPMKOK_01295 1.77e-201 yisR - - K - - - Transcriptional regulator
NKFPMKOK_01296 1.69e-307 yisQ - - V - - - Mate efflux family protein
NKFPMKOK_01297 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NKFPMKOK_01298 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NKFPMKOK_01299 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
NKFPMKOK_01300 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKFPMKOK_01301 4.48e-78 yisL - - S - - - UPF0344 protein
NKFPMKOK_01302 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NKFPMKOK_01303 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
NKFPMKOK_01304 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NKFPMKOK_01305 7.69e-103 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NKFPMKOK_01306 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NKFPMKOK_01307 2.37e-77 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NKFPMKOK_01308 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NKFPMKOK_01309 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
NKFPMKOK_01310 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NKFPMKOK_01311 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NKFPMKOK_01312 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NKFPMKOK_01313 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NKFPMKOK_01314 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
NKFPMKOK_01315 3.47e-108 yhjR - - S - - - Rubrerythrin
NKFPMKOK_01316 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
NKFPMKOK_01317 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_01318 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
NKFPMKOK_01319 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_01320 0.0 yhjG - - CH - - - FAD binding domain
NKFPMKOK_01321 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NKFPMKOK_01322 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
NKFPMKOK_01323 2.77e-63 yhjD - - - - - - -
NKFPMKOK_01324 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
NKFPMKOK_01325 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKFPMKOK_01326 2.64e-63 - - - S - - - Belongs to the UPF0145 family
NKFPMKOK_01327 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
NKFPMKOK_01328 3.92e-157 yrpD - - S - - - Domain of unknown function, YrpD
NKFPMKOK_01329 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
NKFPMKOK_01330 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NKFPMKOK_01331 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NKFPMKOK_01332 5.49e-42 yhzC - - S - - - IDEAL
NKFPMKOK_01333 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_01334 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NKFPMKOK_01335 4.2e-272 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NKFPMKOK_01336 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NKFPMKOK_01337 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NKFPMKOK_01338 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NKFPMKOK_01339 4.57e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NKFPMKOK_01340 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NKFPMKOK_01341 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKFPMKOK_01342 1.33e-293 yhfN - - O - - - Peptidase M48
NKFPMKOK_01343 9.31e-84 yhfM - - - - - - -
NKFPMKOK_01344 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NKFPMKOK_01345 3.92e-137 yhfK - - GM - - - NmrA-like family
NKFPMKOK_01346 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NKFPMKOK_01347 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NKFPMKOK_01348 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKFPMKOK_01349 1.66e-247 yhfE - - G - - - peptidase M42
NKFPMKOK_01351 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKFPMKOK_01352 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NKFPMKOK_01353 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01354 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NKFPMKOK_01355 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NKFPMKOK_01356 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NKFPMKOK_01357 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKFPMKOK_01358 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NKFPMKOK_01359 1.65e-303 yhfA - - C - - - membrane
NKFPMKOK_01360 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NKFPMKOK_01361 9.96e-152 ecsC - - S - - - EcsC protein family
NKFPMKOK_01362 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NKFPMKOK_01363 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NKFPMKOK_01364 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NKFPMKOK_01365 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKFPMKOK_01366 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
NKFPMKOK_01367 2.55e-24 - - - - - - - -
NKFPMKOK_01368 1.58e-53 yhaH - - S - - - YtxH-like protein
NKFPMKOK_01369 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NKFPMKOK_01370 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
NKFPMKOK_01371 4.32e-122 yhaK - - S - - - Putative zincin peptidase
NKFPMKOK_01372 3.2e-182 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NKFPMKOK_01373 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
NKFPMKOK_01374 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NKFPMKOK_01375 0.0 yhaN - - L - - - AAA domain
NKFPMKOK_01376 3.8e-293 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NKFPMKOK_01377 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NKFPMKOK_01378 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01379 1.21e-20 - - - S - - - YhzD-like protein
NKFPMKOK_01380 4.59e-172 yhaR - - I - - - enoyl-CoA hydratase
NKFPMKOK_01382 6.25e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NKFPMKOK_01383 9.07e-263 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NKFPMKOK_01384 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
NKFPMKOK_01385 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NKFPMKOK_01386 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NKFPMKOK_01387 5.48e-69 yheA - - S - - - Belongs to the UPF0342 family
NKFPMKOK_01388 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
NKFPMKOK_01389 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
NKFPMKOK_01390 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
NKFPMKOK_01391 3.53e-48 yheE - - S - - - Family of unknown function (DUF5342)
NKFPMKOK_01392 3.86e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NKFPMKOK_01394 9.64e-127 yheG - - GM - - - NAD(P)H-binding
NKFPMKOK_01395 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NKFPMKOK_01396 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NKFPMKOK_01397 3.96e-107 - - - T - - - universal stress protein
NKFPMKOK_01398 1.17e-118 ymcC - - S - - - Membrane
NKFPMKOK_01399 9.13e-126 pksA - - K - - - Transcriptional regulator
NKFPMKOK_01400 1.05e-191 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NKFPMKOK_01401 6.85e-192 nodB1 - - G - - - deacetylase
NKFPMKOK_01402 1.44e-171 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NKFPMKOK_01403 5.39e-252 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NKFPMKOK_01404 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
NKFPMKOK_01405 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NKFPMKOK_01406 3.46e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKFPMKOK_01407 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKFPMKOK_01408 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NKFPMKOK_01409 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKFPMKOK_01410 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NKFPMKOK_01411 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NKFPMKOK_01412 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NKFPMKOK_01413 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKFPMKOK_01414 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_01415 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
NKFPMKOK_01416 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
NKFPMKOK_01417 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKFPMKOK_01418 1.1e-311 yhdG - - E ko:K03294 - ko00000 amino acid
NKFPMKOK_01419 3.42e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_01420 2.19e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NKFPMKOK_01421 1.7e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01422 2.28e-166 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NKFPMKOK_01423 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NKFPMKOK_01424 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NKFPMKOK_01425 5.72e-314 ygxB - - M - - - Conserved TM helix
NKFPMKOK_01426 1.49e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NKFPMKOK_01427 1.69e-282 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NKFPMKOK_01428 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
NKFPMKOK_01429 1.16e-51 yhdB - - S - - - YhdB-like protein
NKFPMKOK_01430 2.89e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NKFPMKOK_01431 5.61e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKFPMKOK_01432 2.73e-247 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_01433 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NKFPMKOK_01434 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NKFPMKOK_01435 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NKFPMKOK_01436 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NKFPMKOK_01437 2.26e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NKFPMKOK_01438 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKFPMKOK_01439 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKFPMKOK_01440 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
NKFPMKOK_01441 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
NKFPMKOK_01442 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
NKFPMKOK_01443 4.81e-183 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NKFPMKOK_01444 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NKFPMKOK_01445 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NKFPMKOK_01446 2.2e-149 yhcQ - - M - - - Spore coat protein
NKFPMKOK_01447 3.99e-199 yhcP - - - - - - -
NKFPMKOK_01448 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKFPMKOK_01449 5.08e-60 yhcM - - - - - - -
NKFPMKOK_01450 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NKFPMKOK_01451 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKFPMKOK_01452 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NKFPMKOK_01453 6.9e-161 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NKFPMKOK_01454 4.22e-41 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
NKFPMKOK_01455 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKFPMKOK_01456 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01457 8.89e-147 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01458 3.06e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01459 7.54e-65 - - - - - - - -
NKFPMKOK_01460 1.03e-65 yhcC - - - - - - -
NKFPMKOK_01461 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
NKFPMKOK_01462 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NKFPMKOK_01463 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NKFPMKOK_01464 5.25e-76 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NKFPMKOK_01465 2.12e-276 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NKFPMKOK_01466 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NKFPMKOK_01467 1.23e-07 - - - - - - - -
NKFPMKOK_01468 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NKFPMKOK_01469 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NKFPMKOK_01470 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
NKFPMKOK_01471 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NKFPMKOK_01472 8.37e-216 yhbB - - S - - - Putative amidase domain
NKFPMKOK_01473 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NKFPMKOK_01474 1.34e-138 yhzB - - S - - - B3/4 domain
NKFPMKOK_01476 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01477 2.4e-102 ygaO - - - - - - -
NKFPMKOK_01478 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKFPMKOK_01480 1.37e-269 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NKFPMKOK_01481 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NKFPMKOK_01482 2.34e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NKFPMKOK_01483 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NKFPMKOK_01484 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
NKFPMKOK_01485 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NKFPMKOK_01486 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01487 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_01488 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_01489 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKFPMKOK_01490 1.69e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
NKFPMKOK_01492 3.15e-313 ygaK - - C - - - Berberine and berberine like
NKFPMKOK_01493 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NKFPMKOK_01494 2.38e-158 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NKFPMKOK_01495 0.0 - - - C - - - Na+/H+ antiporter family
NKFPMKOK_01497 1.88e-51 - - - - - - - -
NKFPMKOK_01498 5.89e-23 - - - - - - - -
NKFPMKOK_01499 3.15e-87 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
NKFPMKOK_01500 2.01e-79 - - - S - - - Pfam:Phage_holin_4_1
NKFPMKOK_01501 5.7e-14 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
NKFPMKOK_01503 6.24e-220 - - - S - - - Domain of unknown function (DUF2479)
NKFPMKOK_01504 0.0 - - - M - - - Pectate lyase superfamily protein
NKFPMKOK_01505 3e-122 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NKFPMKOK_01507 3.49e-169 - - - D - - - phage tail tape measure protein
NKFPMKOK_01509 4.76e-05 - - - - - - - -
NKFPMKOK_01510 8.37e-21 - - - N - - - Maj_tail_phi13 phage major tail , phi13 family protein
NKFPMKOK_01511 3.28e-13 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
NKFPMKOK_01513 3.54e-30 - - - S - - - Phage head-tail joining protein
NKFPMKOK_01514 2.88e-29 - - - - - - - -
NKFPMKOK_01515 2.56e-05 - - - - - - - -
NKFPMKOK_01516 5.24e-187 - - - S - - - Phage capsid family
NKFPMKOK_01517 4.57e-108 - - - OU - - - Clp protease
NKFPMKOK_01518 7.95e-21 - - - S - - - Phage portal protein
NKFPMKOK_01519 1.85e-160 - - - S - - - Phage portal protein
NKFPMKOK_01520 0.0 - - - L - - - Phage Terminase
NKFPMKOK_01521 3.68e-59 - - - - - - - -
NKFPMKOK_01522 5.24e-22 - - - V - - - HNH endonuclease
NKFPMKOK_01526 2.7e-11 ftsK - - D ko:K03466 - ko00000,ko03036 PFAM cell divisionFtsK SpoIIIE
NKFPMKOK_01527 2.64e-93 - - - L - - - Phage integrase family
NKFPMKOK_01528 4.1e-70 - - - M - - - ArpU family transcriptional regulator
NKFPMKOK_01533 4.86e-59 - - - S - - - dUTPase
NKFPMKOK_01535 8.57e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NKFPMKOK_01537 2.37e-36 - - - - - - - -
NKFPMKOK_01538 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_01539 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NKFPMKOK_01540 1.14e-175 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NKFPMKOK_01541 2.92e-314 - - - E - - - Aminotransferase class I and II
NKFPMKOK_01542 5.87e-155 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NKFPMKOK_01543 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
NKFPMKOK_01544 1.32e-167 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NKFPMKOK_01545 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NKFPMKOK_01546 2.34e-179 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NKFPMKOK_01547 2.91e-197 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NKFPMKOK_01548 6.94e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NKFPMKOK_01549 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NKFPMKOK_01550 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NKFPMKOK_01551 8.93e-96 yclD - - - - - - -
NKFPMKOK_01552 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NKFPMKOK_01553 0.0 yclG - - M - - - Pectate lyase superfamily protein
NKFPMKOK_01555 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
NKFPMKOK_01556 6.53e-290 gerKC - - S ko:K06297 - ko00000 spore germination
NKFPMKOK_01557 5.7e-243 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NKFPMKOK_01558 8.5e-316 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_01559 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKFPMKOK_01560 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NKFPMKOK_01561 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NKFPMKOK_01562 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01563 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NKFPMKOK_01564 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
NKFPMKOK_01565 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NKFPMKOK_01566 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NKFPMKOK_01567 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_01568 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
NKFPMKOK_01569 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NKFPMKOK_01572 1.28e-315 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NKFPMKOK_01573 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_01574 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_01575 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01576 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NKFPMKOK_01577 3.99e-313 ycnB - - EGP - - - the major facilitator superfamily
NKFPMKOK_01578 4.78e-192 ycnC - - K - - - Transcriptional regulator
NKFPMKOK_01579 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
NKFPMKOK_01580 2.79e-59 ycnE - - S - - - Monooxygenase
NKFPMKOK_01581 2.56e-66 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NKFPMKOK_01582 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKFPMKOK_01583 2.59e-279 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKFPMKOK_01584 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKFPMKOK_01585 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NKFPMKOK_01586 1.82e-181 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_01587 6.58e-128 ycnI - - S - - - protein conserved in bacteria
NKFPMKOK_01588 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NKFPMKOK_01589 1.15e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NKFPMKOK_01590 2.18e-69 - - - - - - - -
NKFPMKOK_01591 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NKFPMKOK_01592 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NKFPMKOK_01593 2.79e-255 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NKFPMKOK_01594 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NKFPMKOK_01596 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NKFPMKOK_01597 1.66e-169 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NKFPMKOK_01598 2.33e-265 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NKFPMKOK_01599 7.99e-182 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NKFPMKOK_01600 1.75e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NKFPMKOK_01601 1.09e-227 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NKFPMKOK_01602 2.47e-162 kipR - - K - - - Transcriptional regulator
NKFPMKOK_01603 1.97e-143 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NKFPMKOK_01605 2.73e-71 yczJ - - S - - - biosynthesis
NKFPMKOK_01606 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NKFPMKOK_01607 1.53e-213 ycsN - - S - - - Oxidoreductase
NKFPMKOK_01608 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NKFPMKOK_01609 0.0 ydaB - - IQ - - - acyl-CoA ligase
NKFPMKOK_01610 2.64e-196 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_01611 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NKFPMKOK_01612 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKFPMKOK_01613 4.32e-100 ydaG - - S - - - general stress protein
NKFPMKOK_01614 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NKFPMKOK_01615 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NKFPMKOK_01616 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NKFPMKOK_01617 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKFPMKOK_01618 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NKFPMKOK_01619 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NKFPMKOK_01620 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NKFPMKOK_01621 1.25e-300 ydaM - - M - - - Glycosyl transferase family group 2
NKFPMKOK_01622 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NKFPMKOK_01623 0.0 ydaO - - E - - - amino acid
NKFPMKOK_01624 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NKFPMKOK_01625 5.03e-80 - - - K - - - acetyltransferase
NKFPMKOK_01626 7.58e-111 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NKFPMKOK_01627 1.04e-83 - - - - - - - -
NKFPMKOK_01628 1.77e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NKFPMKOK_01631 1.06e-53 - - - - - - - -
NKFPMKOK_01632 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NKFPMKOK_01635 4.61e-44 ydaT - - - - - - -
NKFPMKOK_01636 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NKFPMKOK_01637 1.7e-64 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NKFPMKOK_01638 6.45e-174 ydbA - - P - - - EcsC protein family
NKFPMKOK_01639 8.2e-08 gsiB - - S ko:K06884 - ko00000 general stress protein
NKFPMKOK_01640 1.04e-75 ydbB - - G - - - Cupin domain
NKFPMKOK_01641 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
NKFPMKOK_01642 6.15e-195 ydbD - - P ko:K07217 - ko00000 Catalase
NKFPMKOK_01643 8.49e-52 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NKFPMKOK_01644 2.07e-171 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NKFPMKOK_01645 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NKFPMKOK_01646 2.66e-146 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NKFPMKOK_01647 4.37e-284 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKFPMKOK_01648 1.85e-225 ydbI - - S - - - AI-2E family transporter
NKFPMKOK_01649 1.79e-216 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01650 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKFPMKOK_01651 1.32e-69 ydbL - - - - - - -
NKFPMKOK_01652 7.84e-256 ydbM - - I - - - acyl-CoA dehydrogenase
NKFPMKOK_01653 2.36e-17 - - - S - - - Fur-regulated basic protein B
NKFPMKOK_01654 6.11e-15 - - - S - - - Fur-regulated basic protein A
NKFPMKOK_01655 1.34e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKFPMKOK_01656 2.25e-74 ydbP - - CO - - - Thioredoxin
NKFPMKOK_01657 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NKFPMKOK_01658 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NKFPMKOK_01659 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NKFPMKOK_01660 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NKFPMKOK_01661 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NKFPMKOK_01662 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NKFPMKOK_01663 7.05e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NKFPMKOK_01664 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NKFPMKOK_01665 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKFPMKOK_01666 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NKFPMKOK_01667 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NKFPMKOK_01668 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NKFPMKOK_01669 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NKFPMKOK_01670 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NKFPMKOK_01671 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NKFPMKOK_01672 3.28e-69 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NKFPMKOK_01673 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NKFPMKOK_01674 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_01675 3.58e-135 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NKFPMKOK_01676 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NKFPMKOK_01677 1.78e-21 - - - - - - - -
NKFPMKOK_01678 6.69e-104 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NKFPMKOK_01686 1.06e-176 - - - I ko:K01066 - ko00000,ko01000 esterase
NKFPMKOK_01687 3.54e-62 ohrB - - O - - - OsmC-like protein
NKFPMKOK_01688 7.77e-65 ohrR - - K - - - Transcriptional regulator
NKFPMKOK_01690 7.99e-71 - - - - - - - -
NKFPMKOK_01691 1.19e-99 - - - K - - - Transcriptional regulator
NKFPMKOK_01692 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKFPMKOK_01693 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NKFPMKOK_01694 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NKFPMKOK_01695 1e-131 - - - S - - - Protein of unknown function (DUF2812)
NKFPMKOK_01696 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
NKFPMKOK_01697 1.99e-300 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKFPMKOK_01698 3.96e-238 ydeG - - EGP - - - Major facilitator superfamily
NKFPMKOK_01699 1.41e-63 - - - S - - - Patatin-like phospholipase
NKFPMKOK_01700 5.81e-57 - - - S - - - Patatin-like phospholipase
NKFPMKOK_01702 8.66e-128 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NKFPMKOK_01703 2.6e-90 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_01704 8.44e-194 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NKFPMKOK_01705 3.58e-201 - - - S - - - SNARE associated Golgi protein
NKFPMKOK_01706 1.19e-124 yrkC - - G - - - Cupin domain
NKFPMKOK_01707 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NKFPMKOK_01708 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NKFPMKOK_01710 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NKFPMKOK_01711 7.14e-63 ydeH - - - - - - -
NKFPMKOK_01712 3.65e-206 - - - S - - - Sodium Bile acid symporter family
NKFPMKOK_01713 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NKFPMKOK_01714 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NKFPMKOK_01715 6.33e-278 nhaC_1 - - C - - - antiporter
NKFPMKOK_01716 1.34e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NKFPMKOK_01717 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01718 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NKFPMKOK_01719 2.13e-129 ydeS - - K - - - Transcriptional regulator
NKFPMKOK_01720 2.99e-192 ydeK - - EG - - - -transporter
NKFPMKOK_01721 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKFPMKOK_01722 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
NKFPMKOK_01723 4.86e-33 yraE - - - ko:K06440 - ko00000 -
NKFPMKOK_01724 2.3e-277 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKFPMKOK_01725 4.76e-84 yraF - - M - - - Spore coat protein
NKFPMKOK_01726 4.73e-47 yraG - - - ko:K06440 - ko00000 -
NKFPMKOK_01727 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NKFPMKOK_01728 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
NKFPMKOK_01729 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NKFPMKOK_01730 4.5e-115 ynaD - - J - - - Acetyltransferase (GNAT) domain
NKFPMKOK_01731 1.37e-188 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_01732 3.1e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NKFPMKOK_01733 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NKFPMKOK_01734 5.7e-281 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKFPMKOK_01735 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_01736 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NKFPMKOK_01737 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NKFPMKOK_01738 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
NKFPMKOK_01739 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKFPMKOK_01740 1.15e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NKFPMKOK_01741 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
NKFPMKOK_01742 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NKFPMKOK_01743 1.47e-144 ydhC - - K - - - FCD
NKFPMKOK_01744 8.62e-69 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKFPMKOK_01745 2.39e-113 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKFPMKOK_01746 5.98e-34 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKFPMKOK_01748 3.98e-311 pbpE - - V - - - Beta-lactamase
NKFPMKOK_01750 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
NKFPMKOK_01751 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NKFPMKOK_01752 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NKFPMKOK_01753 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
NKFPMKOK_01754 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NKFPMKOK_01755 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NKFPMKOK_01756 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NKFPMKOK_01757 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
NKFPMKOK_01758 0.0 ybeC - - E - - - amino acid
NKFPMKOK_01759 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
NKFPMKOK_01760 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NKFPMKOK_01761 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NKFPMKOK_01762 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NKFPMKOK_01786 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NKFPMKOK_01787 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
NKFPMKOK_01788 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NKFPMKOK_01789 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NKFPMKOK_01790 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NKFPMKOK_01791 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NKFPMKOK_01792 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NKFPMKOK_01793 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NKFPMKOK_01794 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NKFPMKOK_01795 1.44e-232 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NKFPMKOK_01796 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NKFPMKOK_01797 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NKFPMKOK_01798 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NKFPMKOK_01799 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NKFPMKOK_01800 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NKFPMKOK_01801 1.66e-96 ytkA - - S - - - YtkA-like
NKFPMKOK_01803 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NKFPMKOK_01804 1.67e-77 ytkC - - S - - - Bacteriophage holin family
NKFPMKOK_01805 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NKFPMKOK_01806 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NKFPMKOK_01807 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NKFPMKOK_01808 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NKFPMKOK_01809 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NKFPMKOK_01810 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
NKFPMKOK_01811 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NKFPMKOK_01812 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKFPMKOK_01813 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NKFPMKOK_01814 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_01815 1.23e-78 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NKFPMKOK_01816 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NKFPMKOK_01817 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NKFPMKOK_01819 4.07e-133 ytqB - - J - - - Putative rRNA methylase
NKFPMKOK_01820 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NKFPMKOK_01821 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
NKFPMKOK_01823 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NKFPMKOK_01824 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01825 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NKFPMKOK_01826 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NKFPMKOK_01827 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NKFPMKOK_01828 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01829 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NKFPMKOK_01830 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_01831 2.32e-216 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NKFPMKOK_01832 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_01833 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NKFPMKOK_01834 4.62e-130 ywaF - - S - - - Integral membrane protein
NKFPMKOK_01835 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
NKFPMKOK_01836 2.97e-171 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NKFPMKOK_01837 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
NKFPMKOK_01838 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NKFPMKOK_01839 8.6e-69 ytwF - - P - - - Sulfurtransferase
NKFPMKOK_01840 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
NKFPMKOK_01841 5.59e-308 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NKFPMKOK_01842 3.37e-77 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NKFPMKOK_01843 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NKFPMKOK_01844 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_01845 3.57e-35 yteV - - S - - - Sporulation protein Cse60
NKFPMKOK_01846 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NKFPMKOK_01847 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NKFPMKOK_01848 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_01849 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NKFPMKOK_01850 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NKFPMKOK_01851 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NKFPMKOK_01852 1.21e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NKFPMKOK_01853 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NKFPMKOK_01854 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NKFPMKOK_01855 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NKFPMKOK_01856 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NKFPMKOK_01857 2.86e-198 ytlQ - - - - - - -
NKFPMKOK_01858 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NKFPMKOK_01859 3.42e-198 ytmP - - M - - - Phosphotransferase
NKFPMKOK_01860 4.54e-59 ytzH - - S - - - YtzH-like protein
NKFPMKOK_01861 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NKFPMKOK_01862 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NKFPMKOK_01863 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NKFPMKOK_01864 9.96e-69 ytzB - - S - - - small secreted protein
NKFPMKOK_01865 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NKFPMKOK_01866 5.33e-98 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NKFPMKOK_01867 2.23e-75 ytpP - - CO - - - Thioredoxin
NKFPMKOK_01868 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
NKFPMKOK_01869 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKFPMKOK_01870 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NKFPMKOK_01871 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NKFPMKOK_01872 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKFPMKOK_01873 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NKFPMKOK_01874 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
NKFPMKOK_01875 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NKFPMKOK_01876 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NKFPMKOK_01877 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NKFPMKOK_01878 1.87e-127 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NKFPMKOK_01879 1.4e-283 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NKFPMKOK_01880 9.68e-138 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NKFPMKOK_01881 9.52e-154 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NKFPMKOK_01882 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKFPMKOK_01883 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKFPMKOK_01884 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
NKFPMKOK_01885 7.21e-154 ygaZ - - E - - - AzlC protein
NKFPMKOK_01886 1.06e-188 - - - K - - - Transcriptional regulator
NKFPMKOK_01887 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKFPMKOK_01888 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
NKFPMKOK_01890 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NKFPMKOK_01893 2.12e-273 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKFPMKOK_01894 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKFPMKOK_01895 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NKFPMKOK_01896 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NKFPMKOK_01897 2.22e-137 yttP - - K - - - Transcriptional regulator
NKFPMKOK_01898 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NKFPMKOK_01899 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NKFPMKOK_01900 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NKFPMKOK_01901 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NKFPMKOK_01902 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKFPMKOK_01903 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
NKFPMKOK_01904 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKFPMKOK_01905 0.0 ytcJ - - S - - - amidohydrolase
NKFPMKOK_01906 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKFPMKOK_01907 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NKFPMKOK_01908 1.31e-103 yteJ - - S - - - RDD family
NKFPMKOK_01909 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
NKFPMKOK_01910 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
NKFPMKOK_01911 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NKFPMKOK_01912 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NKFPMKOK_01913 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKFPMKOK_01914 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NKFPMKOK_01915 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NKFPMKOK_01916 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NKFPMKOK_01918 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_01919 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
NKFPMKOK_01920 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
NKFPMKOK_01921 3.44e-60 ytpI - - S - - - YtpI-like protein
NKFPMKOK_01922 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NKFPMKOK_01923 1.17e-30 - - - - - - - -
NKFPMKOK_01924 3.08e-113 ytrI - - - - - - -
NKFPMKOK_01925 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
NKFPMKOK_01926 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NKFPMKOK_01927 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NKFPMKOK_01928 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NKFPMKOK_01929 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NKFPMKOK_01930 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NKFPMKOK_01931 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NKFPMKOK_01932 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NKFPMKOK_01933 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
NKFPMKOK_01934 1.14e-95 ytwI - - S - - - membrane
NKFPMKOK_01935 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NKFPMKOK_01936 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NKFPMKOK_01937 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NKFPMKOK_01938 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_01939 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NKFPMKOK_01940 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKFPMKOK_01941 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NKFPMKOK_01942 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
NKFPMKOK_01943 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NKFPMKOK_01944 4.68e-198 ytbE - - S - - - reductase
NKFPMKOK_01945 2.72e-250 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NKFPMKOK_01946 7.74e-86 ytcD - - K - - - Transcriptional regulator
NKFPMKOK_01947 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKFPMKOK_01948 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NKFPMKOK_01949 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKFPMKOK_01950 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NKFPMKOK_01951 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NKFPMKOK_01952 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
NKFPMKOK_01953 6.12e-192 ytxC - - S - - - YtxC-like family
NKFPMKOK_01954 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKFPMKOK_01955 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NKFPMKOK_01956 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_01957 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NKFPMKOK_01958 3.71e-65 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
NKFPMKOK_01959 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NKFPMKOK_01960 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NKFPMKOK_01961 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NKFPMKOK_01962 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NKFPMKOK_01963 5.91e-51 ysdA - - S - - - Membrane
NKFPMKOK_01964 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
NKFPMKOK_01965 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NKFPMKOK_01966 6.16e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NKFPMKOK_01967 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NKFPMKOK_01968 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NKFPMKOK_01969 1.4e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NKFPMKOK_01970 1.56e-174 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NKFPMKOK_01971 6.32e-05 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NKFPMKOK_01972 4.26e-234 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NKFPMKOK_01973 8.03e-314 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NKFPMKOK_01974 9.46e-210 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NKFPMKOK_01975 2.11e-78 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NKFPMKOK_01976 3.5e-69 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NKFPMKOK_01978 1.9e-09 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NKFPMKOK_01980 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKFPMKOK_01981 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKFPMKOK_01982 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
NKFPMKOK_01983 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NKFPMKOK_01984 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NKFPMKOK_01985 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NKFPMKOK_01986 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKFPMKOK_01987 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NKFPMKOK_01988 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKFPMKOK_01989 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NKFPMKOK_01990 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKFPMKOK_01991 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NKFPMKOK_01992 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NKFPMKOK_01993 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NKFPMKOK_01994 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NKFPMKOK_01995 2.76e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NKFPMKOK_01996 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
NKFPMKOK_01997 2.63e-74 yhhY - - K - - - FR47-like protein
NKFPMKOK_01998 3.84e-215 yyaD - - S - - - Membrane
NKFPMKOK_01999 1.82e-45 yyzM - - S - - - protein conserved in bacteria
NKFPMKOK_02000 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKFPMKOK_02001 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NKFPMKOK_02002 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NKFPMKOK_02003 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKFPMKOK_02004 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKFPMKOK_02005 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NKFPMKOK_02006 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKFPMKOK_02007 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NKFPMKOK_02008 7.31e-218 ccpB - - K - - - Transcriptional regulator
NKFPMKOK_02009 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_02010 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
NKFPMKOK_02011 4.75e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NKFPMKOK_02012 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NKFPMKOK_02013 1.41e-158 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NKFPMKOK_02014 2.42e-30 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
NKFPMKOK_02015 2.92e-14 - - - KLT - - - serine threonine protein kinase
NKFPMKOK_02017 7.12e-54 - - - E - - - IrrE N-terminal-like domain
NKFPMKOK_02018 1.31e-42 - - - K - - - Transcriptional
NKFPMKOK_02019 5.7e-15 - - - - - - - -
NKFPMKOK_02020 8.45e-32 - - - - - - - -
NKFPMKOK_02022 3.78e-50 - - - S - - - Bacterial protein of unknown function (DUF961)
NKFPMKOK_02023 3.64e-308 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
NKFPMKOK_02024 7.64e-231 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NKFPMKOK_02028 2.46e-53 yddA - - - - - - -
NKFPMKOK_02030 8.56e-164 yddB - - S - - - Conjugative transposon protein TcpC
NKFPMKOK_02031 1.35e-33 yddC - - - - - - -
NKFPMKOK_02032 2.63e-97 yddD - - S - - - TcpE family
NKFPMKOK_02033 0.0 yddE - - S - - - AAA-like domain
NKFPMKOK_02034 4.11e-49 - - - S - - - Domain of unknown function (DUF1874)
NKFPMKOK_02035 5.75e-254 yddG - - S - - - maturation of SSU-rRNA
NKFPMKOK_02036 7.23e-201 yddH - - M - - - Lysozyme-like
NKFPMKOK_02037 7.7e-73 yddI - - - - - - -
NKFPMKOK_02038 2.39e-45 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
NKFPMKOK_02041 1.07e-157 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NKFPMKOK_02042 3.84e-38 - - - L - - - Recombinase
NKFPMKOK_02043 1.17e-30 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NKFPMKOK_02044 1.25e-88 ynaF - - - - - - -
NKFPMKOK_02045 3.34e-36 - - - - - - - -
NKFPMKOK_02046 8.63e-130 - - - S - - - Alpha/beta hydrolase family
NKFPMKOK_02047 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NKFPMKOK_02048 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
NKFPMKOK_02049 7.24e-97 yybA - - K - - - transcriptional
NKFPMKOK_02050 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_02051 2.55e-85 - - - K - - - Winged helix DNA-binding domain
NKFPMKOK_02052 1.56e-144 ydgI - - C - - - nitroreductase
NKFPMKOK_02053 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NKFPMKOK_02054 1.96e-184 - - - G - - - Major Facilitator Superfamily
NKFPMKOK_02055 3.74e-115 - - - S - - - PFAM DinB family protein
NKFPMKOK_02056 7.61e-142 - - - K - - - FCD domain
NKFPMKOK_02057 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NKFPMKOK_02058 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NKFPMKOK_02059 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKFPMKOK_02060 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NKFPMKOK_02061 1.79e-84 yybR - - K - - - Transcriptional regulator
NKFPMKOK_02062 3.93e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
NKFPMKOK_02064 8.64e-189 yybS - - S - - - membrane
NKFPMKOK_02065 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NKFPMKOK_02066 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NKFPMKOK_02067 4.29e-103 - - - KLT - - - COG0515 Serine threonine protein kinase
NKFPMKOK_02068 1.44e-150 - - - S - - - GlcNAc-PI de-N-acetylase
NKFPMKOK_02069 3.93e-279 - - - M - - - Glycosyltransferase Family 4
NKFPMKOK_02070 2.87e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
NKFPMKOK_02071 5.54e-244 - - - S - - - Ecdysteroid kinase
NKFPMKOK_02072 3.86e-271 - - - M - - - Glycosyltransferase Family 4
NKFPMKOK_02073 1.21e-23 yycC - - K - - - YycC-like protein
NKFPMKOK_02075 5.03e-35 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NKFPMKOK_02076 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NKFPMKOK_02077 1.06e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_02078 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NKFPMKOK_02083 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_02084 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_02085 0.0 yycH - - S - - - protein conserved in bacteria
NKFPMKOK_02086 1.1e-191 yycI - - S - - - protein conserved in bacteria
NKFPMKOK_02087 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NKFPMKOK_02088 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKFPMKOK_02089 6.88e-86 - - - S - - - Peptidase propeptide and YPEB domain
NKFPMKOK_02090 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
NKFPMKOK_02091 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NKFPMKOK_02092 8.24e-255 - - - S - - - Major Facilitator Superfamily
NKFPMKOK_02093 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NKFPMKOK_02094 3.82e-57 sdpR - - K - - - transcriptional
NKFPMKOK_02095 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NKFPMKOK_02096 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NKFPMKOK_02097 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NKFPMKOK_02098 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NKFPMKOK_02099 8.34e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
NKFPMKOK_02101 2.13e-106 yycN - - K - - - Acetyltransferase
NKFPMKOK_02102 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NKFPMKOK_02103 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NKFPMKOK_02104 5.96e-264 yycP - - - - - - -
NKFPMKOK_02108 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKFPMKOK_02109 0.0 - - - L - - - AAA ATPase domain
NKFPMKOK_02110 0.0 - - - L - - - AAA domain
NKFPMKOK_02111 6.58e-27 - - - - - - - -
NKFPMKOK_02112 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
NKFPMKOK_02113 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NKFPMKOK_02114 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NKFPMKOK_02115 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NKFPMKOK_02116 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NKFPMKOK_02117 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NKFPMKOK_02118 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NKFPMKOK_02129 4.89e-33 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NKFPMKOK_02130 6.01e-89 yoaW - - - - - - -
NKFPMKOK_02131 1.15e-12 - - - I - - - Acyltransferase family
NKFPMKOK_02132 1.34e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NKFPMKOK_02133 1.93e-112 - - - - - - - -
NKFPMKOK_02135 3.25e-68 - - - - - - - -
NKFPMKOK_02136 1.36e-72 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
NKFPMKOK_02138 3.51e-275 - - - - - - - -
NKFPMKOK_02141 3.87e-73 - - - D - - - Tubulin/FtsZ family, GTPase domain
NKFPMKOK_02145 0.0 - - - - - - - -
NKFPMKOK_02146 1.21e-40 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKFPMKOK_02149 1.77e-281 - - - - - - - -
NKFPMKOK_02154 3.95e-107 - - - - - - - -
NKFPMKOK_02158 4.83e-84 - - - - - - - -
NKFPMKOK_02161 8.93e-72 - - - - - - - -
NKFPMKOK_02162 1.42e-109 - - - - - - - -
NKFPMKOK_02163 2.21e-147 - - - - - - - -
NKFPMKOK_02164 7.02e-72 - - - - - - - -
NKFPMKOK_02166 3.02e-65 - - - - - - - -
NKFPMKOK_02167 4.74e-66 - - - S - - - Domain of unknown function (DUF2479)
NKFPMKOK_02169 2.02e-106 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
NKFPMKOK_02170 2.19e-70 - - - - - - - -
NKFPMKOK_02171 1.28e-64 - - - - - - - -
NKFPMKOK_02172 1.21e-222 - - - A - - - Belongs to the 'phage' integrase family
NKFPMKOK_02175 9.09e-73 - - - - - - - -
NKFPMKOK_02176 0.0 - - - S - - - peptidoglycan catabolic process
NKFPMKOK_02177 8.77e-109 - - - S - - - Phage tail protein
NKFPMKOK_02178 2.04e-242 - - - S - - - Pfam Transposase IS66
NKFPMKOK_02179 8.13e-136 - - - - - - - -
NKFPMKOK_02180 0.0 - - - M - - - Pectate lyase superfamily protein
NKFPMKOK_02181 7.59e-91 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NKFPMKOK_02183 1.24e-43 - - - S - - - Bacteriophage holin
NKFPMKOK_02185 1.05e-06 - - - - - - - -
NKFPMKOK_02186 8.29e-30 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NKFPMKOK_02187 1.34e-214 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NKFPMKOK_02189 1.07e-283 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKFPMKOK_02190 1.04e-52 - - - S - - - YolD-like protein
NKFPMKOK_02191 6.24e-163 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NKFPMKOK_02193 3.18e-67 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NKFPMKOK_02194 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NKFPMKOK_02195 2.26e-209 - - - V - - - HNH endonuclease
NKFPMKOK_02196 7.74e-121 - - - G - - - SMI1-KNR4 cell-wall
NKFPMKOK_02197 1.36e-111 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NKFPMKOK_02198 7.59e-196 yokA - - L - - - Recombinase
NKFPMKOK_02199 8.03e-70 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NKFPMKOK_02200 5.04e-201 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NKFPMKOK_02201 2.17e-56 ymxH - - S - - - YlmC YmxH family
NKFPMKOK_02202 9.39e-296 mlpA - - S - - - Belongs to the peptidase M16 family
NKFPMKOK_02203 1.33e-228 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NKFPMKOK_02204 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NKFPMKOK_02205 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKFPMKOK_02206 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NKFPMKOK_02207 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKFPMKOK_02208 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKFPMKOK_02209 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NKFPMKOK_02210 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKFPMKOK_02211 6.16e-63 ylxQ - - J - - - ribosomal protein
NKFPMKOK_02212 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NKFPMKOK_02213 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NKFPMKOK_02214 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NKFPMKOK_02215 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKFPMKOK_02216 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NKFPMKOK_02217 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NKFPMKOK_02218 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NKFPMKOK_02219 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NKFPMKOK_02220 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKFPMKOK_02221 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NKFPMKOK_02222 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NKFPMKOK_02223 3.83e-199 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKFPMKOK_02224 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NKFPMKOK_02225 2.54e-84 ylxL - - - - - - -
NKFPMKOK_02226 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02227 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NKFPMKOK_02228 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NKFPMKOK_02229 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NKFPMKOK_02230 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NKFPMKOK_02231 2.95e-241 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NKFPMKOK_02232 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NKFPMKOK_02233 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NKFPMKOK_02234 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKFPMKOK_02235 1.34e-237 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKFPMKOK_02236 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NKFPMKOK_02237 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NKFPMKOK_02238 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NKFPMKOK_02239 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NKFPMKOK_02240 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NKFPMKOK_02241 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NKFPMKOK_02242 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKFPMKOK_02243 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NKFPMKOK_02244 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NKFPMKOK_02245 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NKFPMKOK_02246 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NKFPMKOK_02247 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
NKFPMKOK_02248 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NKFPMKOK_02249 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NKFPMKOK_02250 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NKFPMKOK_02251 4.1e-228 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKFPMKOK_02252 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NKFPMKOK_02253 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NKFPMKOK_02254 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NKFPMKOK_02255 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NKFPMKOK_02256 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NKFPMKOK_02257 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NKFPMKOK_02258 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NKFPMKOK_02259 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NKFPMKOK_02260 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NKFPMKOK_02261 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKFPMKOK_02262 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NKFPMKOK_02263 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NKFPMKOK_02264 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NKFPMKOK_02265 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NKFPMKOK_02266 0.0 ylqG - - - - - - -
NKFPMKOK_02267 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKFPMKOK_02268 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKFPMKOK_02269 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NKFPMKOK_02270 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NKFPMKOK_02271 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKFPMKOK_02272 5.66e-79 ylqD - - S - - - YlqD protein
NKFPMKOK_02273 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NKFPMKOK_02274 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NKFPMKOK_02275 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKFPMKOK_02276 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NKFPMKOK_02277 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NKFPMKOK_02278 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NKFPMKOK_02279 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NKFPMKOK_02280 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKFPMKOK_02281 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NKFPMKOK_02282 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NKFPMKOK_02283 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NKFPMKOK_02284 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NKFPMKOK_02285 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKFPMKOK_02286 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NKFPMKOK_02287 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NKFPMKOK_02288 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NKFPMKOK_02289 6.07e-77 yloU - - S - - - protein conserved in bacteria
NKFPMKOK_02290 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NKFPMKOK_02291 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NKFPMKOK_02292 4.85e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NKFPMKOK_02293 6.97e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NKFPMKOK_02294 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NKFPMKOK_02295 4.92e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NKFPMKOK_02296 7.22e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NKFPMKOK_02297 2.98e-315 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKFPMKOK_02298 3.85e-214 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKFPMKOK_02299 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKFPMKOK_02300 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKFPMKOK_02301 2e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKFPMKOK_02302 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NKFPMKOK_02303 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NKFPMKOK_02304 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NKFPMKOK_02305 8e-194 yloC - - S - - - stress-induced protein
NKFPMKOK_02306 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NKFPMKOK_02307 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NKFPMKOK_02308 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NKFPMKOK_02309 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NKFPMKOK_02310 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NKFPMKOK_02311 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NKFPMKOK_02312 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NKFPMKOK_02313 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NKFPMKOK_02314 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NKFPMKOK_02315 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NKFPMKOK_02316 1e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NKFPMKOK_02317 1.17e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NKFPMKOK_02318 2.36e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NKFPMKOK_02319 6.57e-177 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NKFPMKOK_02320 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NKFPMKOK_02321 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NKFPMKOK_02322 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NKFPMKOK_02323 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NKFPMKOK_02324 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NKFPMKOK_02325 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NKFPMKOK_02326 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NKFPMKOK_02327 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NKFPMKOK_02328 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NKFPMKOK_02329 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NKFPMKOK_02330 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NKFPMKOK_02331 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
NKFPMKOK_02332 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NKFPMKOK_02333 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NKFPMKOK_02334 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NKFPMKOK_02335 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NKFPMKOK_02336 7.13e-52 ylmC - - S - - - sporulation protein
NKFPMKOK_02337 6.78e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NKFPMKOK_02338 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NKFPMKOK_02339 3.12e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02340 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02341 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NKFPMKOK_02342 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NKFPMKOK_02343 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKFPMKOK_02344 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NKFPMKOK_02345 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NKFPMKOK_02346 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NKFPMKOK_02347 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKFPMKOK_02348 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NKFPMKOK_02349 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NKFPMKOK_02350 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKFPMKOK_02351 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKFPMKOK_02352 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NKFPMKOK_02353 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NKFPMKOK_02354 2.81e-67 ftsL - - D - - - Essential cell division protein
NKFPMKOK_02355 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NKFPMKOK_02356 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NKFPMKOK_02357 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NKFPMKOK_02358 4.46e-190 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKFPMKOK_02359 2.68e-115 ylbP - - K - - - n-acetyltransferase
NKFPMKOK_02360 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NKFPMKOK_02361 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NKFPMKOK_02362 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NKFPMKOK_02363 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
NKFPMKOK_02364 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NKFPMKOK_02365 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NKFPMKOK_02366 8.16e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NKFPMKOK_02367 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKFPMKOK_02368 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NKFPMKOK_02369 4.62e-56 ylbG - - S - - - UPF0298 protein
NKFPMKOK_02370 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
NKFPMKOK_02371 1.73e-48 ylbE - - S - - - YlbE-like protein
NKFPMKOK_02372 5.5e-83 ylbD - - S - - - Putative coat protein
NKFPMKOK_02373 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
NKFPMKOK_02374 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
NKFPMKOK_02375 8.01e-77 ylbA - - S - - - YugN-like family
NKFPMKOK_02376 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NKFPMKOK_02377 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NKFPMKOK_02378 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NKFPMKOK_02379 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKFPMKOK_02380 3.95e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NKFPMKOK_02381 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKFPMKOK_02382 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NKFPMKOK_02383 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NKFPMKOK_02384 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NKFPMKOK_02385 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
NKFPMKOK_02386 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NKFPMKOK_02387 4.45e-104 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NKFPMKOK_02388 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NKFPMKOK_02389 2.67e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKFPMKOK_02390 7.95e-45 ylaI - - S - - - protein conserved in bacteria
NKFPMKOK_02391 1.41e-64 - - - S - - - YlaH-like protein
NKFPMKOK_02392 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NKFPMKOK_02393 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
NKFPMKOK_02394 1.97e-52 ylaE - - - - - - -
NKFPMKOK_02396 9.3e-32 ylaA - - - - - - -
NKFPMKOK_02397 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NKFPMKOK_02398 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
NKFPMKOK_02399 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NKFPMKOK_02400 7.89e-32 ykzI - - - - - - -
NKFPMKOK_02401 2.73e-153 yktB - - S - - - Belongs to the UPF0637 family
NKFPMKOK_02402 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
NKFPMKOK_02403 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NKFPMKOK_02404 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NKFPMKOK_02405 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NKFPMKOK_02406 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKFPMKOK_02407 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKFPMKOK_02408 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKFPMKOK_02409 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKFPMKOK_02410 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
NKFPMKOK_02411 4.93e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NKFPMKOK_02412 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKFPMKOK_02413 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
NKFPMKOK_02414 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
NKFPMKOK_02415 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKFPMKOK_02416 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NKFPMKOK_02417 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NKFPMKOK_02418 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NKFPMKOK_02419 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NKFPMKOK_02420 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NKFPMKOK_02421 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NKFPMKOK_02422 7.7e-19 - - - S - - - Uncharacterized protein YkpC
NKFPMKOK_02423 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NKFPMKOK_02424 4.63e-200 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKFPMKOK_02425 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKFPMKOK_02426 3.54e-48 ykoA - - - - - - -
NKFPMKOK_02427 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NKFPMKOK_02428 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NKFPMKOK_02429 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NKFPMKOK_02430 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_02431 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NKFPMKOK_02432 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_02433 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKFPMKOK_02434 5.77e-134 yknW - - S - - - Yip1 domain
NKFPMKOK_02435 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NKFPMKOK_02436 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NKFPMKOK_02437 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NKFPMKOK_02438 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NKFPMKOK_02439 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKFPMKOK_02440 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NKFPMKOK_02441 8.39e-201 yknT - - - ko:K06437 - ko00000 -
NKFPMKOK_02442 3.55e-125 rok - - K - - - Repressor of ComK
NKFPMKOK_02444 1.9e-93 ykuV - - CO - - - thiol-disulfide
NKFPMKOK_02446 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NKFPMKOK_02447 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
NKFPMKOK_02448 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NKFPMKOK_02449 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NKFPMKOK_02450 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
NKFPMKOK_02451 1.07e-207 ykuO - - - - - - -
NKFPMKOK_02452 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
NKFPMKOK_02453 1.08e-214 ccpC - - K - - - Transcriptional regulator
NKFPMKOK_02454 8.55e-99 ykuL - - S - - - CBS domain
NKFPMKOK_02455 2.63e-36 ykzF - - S - - - Antirepressor AbbA
NKFPMKOK_02456 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
NKFPMKOK_02457 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
NKFPMKOK_02458 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
NKFPMKOK_02460 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKFPMKOK_02461 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NKFPMKOK_02462 3.48e-114 ykuD - - S - - - protein conserved in bacteria
NKFPMKOK_02463 8.16e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_02464 1.45e-107 ykyB - - S - - - YkyB-like protein
NKFPMKOK_02465 5.31e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NKFPMKOK_02466 2.22e-15 - - - - - - - -
NKFPMKOK_02467 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NKFPMKOK_02468 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_02469 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NKFPMKOK_02470 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
NKFPMKOK_02471 9.19e-65 - - - - - - - -
NKFPMKOK_02472 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NKFPMKOK_02473 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NKFPMKOK_02474 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NKFPMKOK_02475 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_02476 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NKFPMKOK_02477 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NKFPMKOK_02478 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_02479 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NKFPMKOK_02480 4.21e-217 ykvZ - - K - - - Transcriptional regulator
NKFPMKOK_02481 1.51e-259 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NKFPMKOK_02482 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NKFPMKOK_02483 1.04e-105 stoA - - CO - - - thiol-disulfide
NKFPMKOK_02484 1.16e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_02485 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NKFPMKOK_02486 8.76e-38 - - - - - - - -
NKFPMKOK_02487 1.56e-34 ykvS - - S - - - protein conserved in bacteria
NKFPMKOK_02488 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
NKFPMKOK_02489 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKFPMKOK_02490 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NKFPMKOK_02491 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NKFPMKOK_02492 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NKFPMKOK_02493 1.81e-196 - - - - - - - -
NKFPMKOK_02495 6.18e-222 ykvI - - S - - - membrane
NKFPMKOK_02496 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NKFPMKOK_02497 5.97e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NKFPMKOK_02498 1.19e-159 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NKFPMKOK_02499 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NKFPMKOK_02500 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NKFPMKOK_02502 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NKFPMKOK_02503 9.6e-141 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NKFPMKOK_02504 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NKFPMKOK_02505 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NKFPMKOK_02506 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NKFPMKOK_02507 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKFPMKOK_02508 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NKFPMKOK_02509 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NKFPMKOK_02511 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKFPMKOK_02512 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_02513 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NKFPMKOK_02514 1.37e-26 ykzE - - - - - - -
NKFPMKOK_02515 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
NKFPMKOK_02516 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NKFPMKOK_02517 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NKFPMKOK_02518 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
NKFPMKOK_02519 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NKFPMKOK_02520 1.17e-219 ykrI - - S - - - Anti-sigma factor N-terminus
NKFPMKOK_02521 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02522 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NKFPMKOK_02523 1.21e-123 ykoX - - S - - - membrane-associated protein
NKFPMKOK_02524 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NKFPMKOK_02525 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NKFPMKOK_02526 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NKFPMKOK_02527 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
NKFPMKOK_02528 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NKFPMKOK_02529 3.57e-35 ykoL - - - - - - -
NKFPMKOK_02530 2.24e-23 - - - - - - - -
NKFPMKOK_02531 3.53e-69 tnrA - - K - - - transcriptional
NKFPMKOK_02532 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NKFPMKOK_02534 5.3e-302 ydhD - - M - - - Glycosyl hydrolase
NKFPMKOK_02535 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NKFPMKOK_02536 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NKFPMKOK_02537 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NKFPMKOK_02538 2.08e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKFPMKOK_02539 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NKFPMKOK_02540 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKFPMKOK_02541 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NKFPMKOK_02542 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_02543 1.01e-149 - - - K - - - Collagen triple helix repeat
NKFPMKOK_02544 2.15e-260 - - - M - - - Glycosyl transferase family 2
NKFPMKOK_02546 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NKFPMKOK_02547 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
NKFPMKOK_02548 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
NKFPMKOK_02549 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
NKFPMKOK_02550 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKFPMKOK_02551 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKFPMKOK_02552 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NKFPMKOK_02553 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NKFPMKOK_02554 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NKFPMKOK_02555 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKFPMKOK_02556 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
NKFPMKOK_02557 1.45e-179 ykgA - - E - - - Amidinotransferase
NKFPMKOK_02558 1.23e-255 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NKFPMKOK_02559 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_02560 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKFPMKOK_02561 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NKFPMKOK_02562 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NKFPMKOK_02563 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NKFPMKOK_02564 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_02565 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_02566 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKFPMKOK_02567 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NKFPMKOK_02568 0.0 yubD - - P - - - Major Facilitator Superfamily
NKFPMKOK_02569 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKFPMKOK_02571 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NKFPMKOK_02572 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NKFPMKOK_02573 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NKFPMKOK_02574 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
NKFPMKOK_02575 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NKFPMKOK_02576 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
NKFPMKOK_02577 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NKFPMKOK_02578 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NKFPMKOK_02579 4.2e-207 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NKFPMKOK_02580 7.53e-49 xhlB - - S - - - SPP1 phage holin
NKFPMKOK_02581 6.44e-50 xhlA - - S - - - Haemolysin XhlA
NKFPMKOK_02582 2.97e-167 xepA - - - - - - -
NKFPMKOK_02583 1.05e-36 xkdX - - - - - - -
NKFPMKOK_02585 1.04e-194 - - - - - - - -
NKFPMKOK_02586 1.48e-36 - - - - - - - -
NKFPMKOK_02587 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NKFPMKOK_02588 7.44e-208 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKFPMKOK_02589 2.35e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
NKFPMKOK_02590 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
NKFPMKOK_02591 2.78e-208 xkdQ - - G - - - NLP P60 protein
NKFPMKOK_02592 2.87e-129 xkdP - - S - - - Lysin motif
NKFPMKOK_02593 7.01e-277 xkdO - - L - - - Transglycosylase SLT domain
NKFPMKOK_02594 4.33e-27 - - - - - - - -
NKFPMKOK_02595 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NKFPMKOK_02596 8.21e-97 xkdM - - S - - - Phage tail tube protein
NKFPMKOK_02597 3.64e-284 xkdK - - S - - - Phage tail sheath C-terminal domain
NKFPMKOK_02598 3.86e-21 - - - - - - - -
NKFPMKOK_02599 1.82e-75 xkdJ - - - - - - -
NKFPMKOK_02600 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NKFPMKOK_02602 8.84e-61 yqbG - - S - - - Protein of unknown function (DUF3199)
NKFPMKOK_02603 3.38e-202 xkdG - - S - - - Phage capsid family
NKFPMKOK_02604 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
NKFPMKOK_02605 4.94e-302 xkdE3 - - S - - - portal protein
NKFPMKOK_02606 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NKFPMKOK_02607 1.37e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NKFPMKOK_02608 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKFPMKOK_02612 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
NKFPMKOK_02614 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_02615 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
NKFPMKOK_02616 2.69e-128 yjqB - - S - - - phage-related replication protein
NKFPMKOK_02617 3.19e-79 yjqA - - S - - - Bacterial PH domain
NKFPMKOK_02618 9.27e-128 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NKFPMKOK_02619 2.62e-60 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NKFPMKOK_02621 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NKFPMKOK_02622 9.4e-100 yjoA - - S - - - DinB family
NKFPMKOK_02623 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NKFPMKOK_02625 3.01e-165 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NKFPMKOK_02626 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
NKFPMKOK_02627 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NKFPMKOK_02628 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NKFPMKOK_02629 2.92e-80 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NKFPMKOK_02630 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NKFPMKOK_02631 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NKFPMKOK_02632 1.47e-110 yjlB - - S - - - Cupin domain
NKFPMKOK_02633 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NKFPMKOK_02634 4.5e-159 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
NKFPMKOK_02635 1.72e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NKFPMKOK_02636 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NKFPMKOK_02637 1.73e-40 - - - - - - - -
NKFPMKOK_02638 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKFPMKOK_02639 7.68e-274 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NKFPMKOK_02640 5.56e-111 yjgD - - S - - - Protein of unknown function (DUF1641)
NKFPMKOK_02641 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NKFPMKOK_02642 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
NKFPMKOK_02643 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
NKFPMKOK_02644 1.07e-28 yjfB - - S - - - Putative motility protein
NKFPMKOK_02646 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NKFPMKOK_02647 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_02648 3.81e-45 - - - - - - - -
NKFPMKOK_02649 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
NKFPMKOK_02650 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NKFPMKOK_02651 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKFPMKOK_02652 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_02653 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKFPMKOK_02654 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NKFPMKOK_02655 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_02656 5.5e-302 yfjF - - EGP - - - Belongs to the major facilitator superfamily
NKFPMKOK_02657 7.1e-58 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NKFPMKOK_02658 3.78e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NKFPMKOK_02660 4.57e-21 - - - N - - - Kelch motif
NKFPMKOK_02661 0.000667 KLHL36 - - T ko:K13958 - ko00000,ko04121 protein modification by small protein conjugation
NKFPMKOK_02665 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
NKFPMKOK_02666 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKFPMKOK_02667 9.18e-49 - - - S - - - YolD-like protein
NKFPMKOK_02668 0.0 - - - K - - - Psort location Cytoplasmic, score
NKFPMKOK_02669 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
NKFPMKOK_02674 3.54e-282 - - - M - - - domain protein
NKFPMKOK_02675 7.55e-59 orfX1 - - L - - - Transposase
NKFPMKOK_02676 5.6e-173 - - - L - - - Integrase core domain
NKFPMKOK_02679 2e-26 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG3505 Type IV secretory pathway, VirD4 components
NKFPMKOK_02681 6.38e-87 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NKFPMKOK_02682 1.88e-299 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
NKFPMKOK_02683 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NKFPMKOK_02684 5.89e-138 - - - L - - - IstB-like ATP binding protein
NKFPMKOK_02686 8.62e-236 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NKFPMKOK_02687 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NKFPMKOK_02688 6.09e-310 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NKFPMKOK_02689 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
NKFPMKOK_02690 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NKFPMKOK_02691 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NKFPMKOK_02692 2.36e-166 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKFPMKOK_02693 2.98e-247 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NKFPMKOK_02694 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKFPMKOK_02695 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKFPMKOK_02696 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NKFPMKOK_02697 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
NKFPMKOK_02698 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NKFPMKOK_02699 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NKFPMKOK_02700 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
NKFPMKOK_02701 9.33e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
NKFPMKOK_02702 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKFPMKOK_02703 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_02704 2.18e-172 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NKFPMKOK_02705 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NKFPMKOK_02706 4.79e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NKFPMKOK_02707 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NKFPMKOK_02708 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NKFPMKOK_02709 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NKFPMKOK_02710 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NKFPMKOK_02711 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
NKFPMKOK_02712 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NKFPMKOK_02713 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NKFPMKOK_02714 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NKFPMKOK_02715 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NKFPMKOK_02716 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_02717 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_02718 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NKFPMKOK_02719 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NKFPMKOK_02720 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NKFPMKOK_02721 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NKFPMKOK_02722 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NKFPMKOK_02727 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NKFPMKOK_02728 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NKFPMKOK_02729 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKFPMKOK_02730 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKFPMKOK_02731 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NKFPMKOK_02732 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKFPMKOK_02733 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKFPMKOK_02734 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
NKFPMKOK_02735 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NKFPMKOK_02736 8.92e-291 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKFPMKOK_02737 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NKFPMKOK_02738 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NKFPMKOK_02739 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NKFPMKOK_02740 3.63e-110 ysxD - - - - - - -
NKFPMKOK_02741 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NKFPMKOK_02742 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NKFPMKOK_02743 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NKFPMKOK_02744 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NKFPMKOK_02745 1.98e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NKFPMKOK_02746 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NKFPMKOK_02747 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NKFPMKOK_02748 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NKFPMKOK_02749 3.61e-34 - - - - - - - -
NKFPMKOK_02750 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NKFPMKOK_02751 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NKFPMKOK_02752 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NKFPMKOK_02753 4.15e-191 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NKFPMKOK_02754 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NKFPMKOK_02755 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NKFPMKOK_02756 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NKFPMKOK_02757 4.16e-200 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NKFPMKOK_02758 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NKFPMKOK_02759 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NKFPMKOK_02760 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NKFPMKOK_02761 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NKFPMKOK_02762 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NKFPMKOK_02763 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NKFPMKOK_02764 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NKFPMKOK_02765 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NKFPMKOK_02766 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NKFPMKOK_02767 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NKFPMKOK_02768 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NKFPMKOK_02769 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NKFPMKOK_02770 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NKFPMKOK_02771 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NKFPMKOK_02772 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NKFPMKOK_02773 1.3e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NKFPMKOK_02774 1.15e-260 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NKFPMKOK_02775 1.61e-214 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NKFPMKOK_02776 1.26e-60 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKFPMKOK_02778 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NKFPMKOK_02779 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NKFPMKOK_02780 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NKFPMKOK_02781 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
NKFPMKOK_02782 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKFPMKOK_02783 9.18e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NKFPMKOK_02784 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NKFPMKOK_02785 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
NKFPMKOK_02786 1.16e-133 yrbG - - S - - - membrane
NKFPMKOK_02787 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_02788 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
NKFPMKOK_02789 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NKFPMKOK_02790 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NKFPMKOK_02791 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NKFPMKOK_02792 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NKFPMKOK_02793 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKFPMKOK_02794 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKFPMKOK_02795 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NKFPMKOK_02796 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NKFPMKOK_02799 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NKFPMKOK_02800 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NKFPMKOK_02801 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NKFPMKOK_02802 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NKFPMKOK_02803 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_02804 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NKFPMKOK_02805 8.02e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NKFPMKOK_02806 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
NKFPMKOK_02807 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NKFPMKOK_02808 9e-101 yrrD - - S - - - protein conserved in bacteria
NKFPMKOK_02809 8.4e-42 yrzR - - - - - - -
NKFPMKOK_02810 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
NKFPMKOK_02811 1.41e-134 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NKFPMKOK_02812 4.6e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NKFPMKOK_02813 5.82e-185 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NKFPMKOK_02814 1.43e-164 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NKFPMKOK_02815 4.09e-231 yrrI - - S - - - AI-2E family transporter
NKFPMKOK_02816 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKFPMKOK_02817 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
NKFPMKOK_02818 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKFPMKOK_02819 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
NKFPMKOK_02820 6.36e-256 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKFPMKOK_02821 4.49e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NKFPMKOK_02822 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NKFPMKOK_02823 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NKFPMKOK_02824 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NKFPMKOK_02825 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NKFPMKOK_02826 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NKFPMKOK_02827 8.77e-104 yrrS - - S - - - Protein of unknown function (DUF1510)
NKFPMKOK_02828 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
NKFPMKOK_02829 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NKFPMKOK_02830 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NKFPMKOK_02831 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NKFPMKOK_02832 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NKFPMKOK_02833 1.35e-46 yrhC - - S - - - YrhC-like protein
NKFPMKOK_02834 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
NKFPMKOK_02835 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
NKFPMKOK_02836 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NKFPMKOK_02837 4.62e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NKFPMKOK_02838 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NKFPMKOK_02839 3.67e-120 yrhH - - Q - - - methyltransferase
NKFPMKOK_02840 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NKFPMKOK_02841 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NKFPMKOK_02842 1.32e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_02843 5.33e-211 yybE - - K - - - Transcriptional regulator
NKFPMKOK_02844 1.88e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NKFPMKOK_02845 9.54e-229 romA - - S - - - Beta-lactamase superfamily domain
NKFPMKOK_02846 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NKFPMKOK_02847 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_02848 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NKFPMKOK_02849 2.38e-167 - - - K - - - Helix-turn-helix domain, rpiR family
NKFPMKOK_02850 7.33e-67 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NKFPMKOK_02851 5.2e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NKFPMKOK_02852 1.14e-187 supH - - S - - - hydrolase
NKFPMKOK_02854 2.76e-120 - - - S - - - DinB family
NKFPMKOK_02855 6.08e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NKFPMKOK_02856 5.34e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_02857 1.84e-126 yqaC - - F - - - adenylate kinase activity
NKFPMKOK_02859 3.5e-47 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NKFPMKOK_02860 1.02e-79 - - - K - - - Transcriptional regulator PadR-like family
NKFPMKOK_02861 1.25e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NKFPMKOK_02862 6.77e-21 xkdG - - S - - - Phage capsid family
NKFPMKOK_02863 1.29e-89 - - - K - - - MerR family transcriptional regulator
NKFPMKOK_02864 1.23e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
NKFPMKOK_02865 8.03e-141 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NKFPMKOK_02866 8.55e-19 xkdS - - S - - - Protein of unknown function (DUF2634)
NKFPMKOK_02868 5.49e-13 - - - S - - - SMI1-KNR4 cell-wall
NKFPMKOK_02872 1.39e-24 - - - - - - - -
NKFPMKOK_02873 2.68e-135 lin0465 - - S - - - DJ-1/PfpI family
NKFPMKOK_02874 1.28e-206 - - - K ko:K13572 - ko00000,ko03051 HTH domain
NKFPMKOK_02876 2.82e-142 mchB - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 Thioesterase involved in non-ribosomal peptide biosynthesis
NKFPMKOK_02877 5.94e-257 glyA_1 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKFPMKOK_02878 4.19e-152 - - - S - - - Winged helix DNA-binding domain
NKFPMKOK_02879 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
NKFPMKOK_02880 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
NKFPMKOK_02881 4.17e-221 - 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 phenylacetate-CoA ligase activity
NKFPMKOK_02882 1.71e-224 - 4.1.3.27, 4.2.99.21, 5.4.4.2 - EH ko:K01657,ko:K04781 ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I domain protein
NKFPMKOK_02883 2.93e-98 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 TIGRFAM glutamine amidotransferase of anthranilate synthase
NKFPMKOK_02884 1.78e-199 smvA - - EGP ko:K08167 - ko00000,ko00002,ko01504,ko02000 Major facilitator superfamily
NKFPMKOK_02885 6.3e-11 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
NKFPMKOK_02886 1.18e-50 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NKFPMKOK_02887 1.46e-194 - - - L - - - AAA ATPase domain
NKFPMKOK_02888 1.82e-17 - - - L ko:K06400 - ko00000 Recombinase
NKFPMKOK_02889 1.01e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02890 3.32e-124 xkdA - - E - - - IrrE N-terminal-like domain
NKFPMKOK_02893 1.25e-74 - - - K - - - sequence-specific DNA binding
NKFPMKOK_02894 2.23e-47 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_02896 1.04e-133 - - - - - - - -
NKFPMKOK_02900 1.21e-215 yqaJ - - L - - - YqaJ-like viral recombinase domain
NKFPMKOK_02901 1.38e-192 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NKFPMKOK_02902 4.84e-148 yqaL - - L - - - DnaD domain protein
NKFPMKOK_02903 6.14e-208 yqaM - - L - - - IstB-like ATP binding protein
NKFPMKOK_02905 1.82e-93 rusA - - L - - - Endodeoxyribonuclease RusA
NKFPMKOK_02906 2.05e-42 yqaO - - S - - - Phage-like element PBSX protein XtrA
NKFPMKOK_02907 4.33e-70 - - - S - - - Psort location Cytoplasmic, score
NKFPMKOK_02908 2.06e-61 - - - S - - - Beta protein
NKFPMKOK_02909 4.9e-100 yqaQ - - L - - - Transposase
NKFPMKOK_02913 3.38e-70 - - - - - - - -
NKFPMKOK_02914 5.01e-110 yqaS - - L - - - DNA packaging
NKFPMKOK_02915 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
NKFPMKOK_02916 0.0 yqbA - - S - - - portal protein
NKFPMKOK_02917 2.42e-190 - - - S - - - Phage Mu protein F like protein
NKFPMKOK_02919 1.43e-165 yqbD - - L - - - Putative phage serine protease XkdF
NKFPMKOK_02920 1.86e-215 xkdG - - S - - - Phage capsid family
NKFPMKOK_02921 5.19e-61 - - - S - - - YqbF, hypothetical protein domain
NKFPMKOK_02922 1.01e-87 - - - S - - - Protein of unknown function (DUF3199)
NKFPMKOK_02923 1.61e-81 yqbH - - S - - - Domain of unknown function (DUF3599)
NKFPMKOK_02924 2.66e-113 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NKFPMKOK_02925 3e-98 yqbJ - - - - - - -
NKFPMKOK_02926 2.44e-34 - - - - - - - -
NKFPMKOK_02927 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NKFPMKOK_02928 2.02e-97 xkdM - - S - - - Phage tail tube protein
NKFPMKOK_02929 6.07e-247 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
NKFPMKOK_02930 6.02e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NKFPMKOK_02931 0.0 xkdO - - L - - - Transglycosylase SLT domain
NKFPMKOK_02932 4.43e-154 xkdP - - S - - - Lysin motif
NKFPMKOK_02933 4.44e-226 xkdQ - - G - - - NLP P60 protein
NKFPMKOK_02934 9.93e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
NKFPMKOK_02935 7.71e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
NKFPMKOK_02936 3.45e-241 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKFPMKOK_02937 5.52e-126 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NKFPMKOK_02938 7.09e-53 - - - - - - - -
NKFPMKOK_02939 1.33e-279 - - - - - - - -
NKFPMKOK_02940 8.96e-68 xkdW - - S - - - XkdW protein
NKFPMKOK_02941 8.73e-29 - - - - - - - -
NKFPMKOK_02942 1.15e-202 xepA - - - - - - -
NKFPMKOK_02943 4.84e-88 - - - S - - - Bacteriophage holin family
NKFPMKOK_02944 6.73e-178 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NKFPMKOK_02946 6.31e-79 - - - - - - - -
NKFPMKOK_02949 9.89e-288 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NKFPMKOK_02951 1.49e-78 - - - S - - - Tetratricopeptide repeat
NKFPMKOK_02952 9.16e-26 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NKFPMKOK_02954 4.11e-134 yrkC - - G - - - Cupin domain
NKFPMKOK_02955 3.21e-11 yrkD - - S - - - protein conserved in bacteria
NKFPMKOK_02956 0.0 - - - L ko:K06400 - ko00000 Recombinase
NKFPMKOK_02957 3.66e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_02958 2.47e-274 - - - EGP - - - Transmembrane secretion effector
NKFPMKOK_02959 9.72e-08 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NKFPMKOK_02961 3.41e-137 yqeD - - S - - - SNARE associated Golgi protein
NKFPMKOK_02962 3.16e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NKFPMKOK_02963 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NKFPMKOK_02965 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NKFPMKOK_02966 1.87e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NKFPMKOK_02967 2.83e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKFPMKOK_02968 1.49e-59 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NKFPMKOK_02969 1.38e-138 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKFPMKOK_02970 3.25e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NKFPMKOK_02971 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NKFPMKOK_02972 1.98e-177 yqeM - - Q - - - Methyltransferase
NKFPMKOK_02973 1.14e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKFPMKOK_02974 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NKFPMKOK_02975 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NKFPMKOK_02976 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NKFPMKOK_02977 6.09e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NKFPMKOK_02978 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NKFPMKOK_02979 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NKFPMKOK_02980 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NKFPMKOK_02981 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
NKFPMKOK_02982 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NKFPMKOK_02983 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NKFPMKOK_02984 1.11e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NKFPMKOK_02985 1.99e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKFPMKOK_02986 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NKFPMKOK_02987 6.71e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NKFPMKOK_02988 1.27e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NKFPMKOK_02989 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NKFPMKOK_02990 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NKFPMKOK_02991 1.99e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NKFPMKOK_02992 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NKFPMKOK_02993 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NKFPMKOK_02994 3.91e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NKFPMKOK_02995 1.22e-186 yqfA - - S - - - UPF0365 protein
NKFPMKOK_02996 2.58e-48 yqfB - - - - - - -
NKFPMKOK_02997 3.57e-61 yqfC - - S - - - sporulation protein YqfC
NKFPMKOK_02998 3.96e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NKFPMKOK_02999 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NKFPMKOK_03000 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NKFPMKOK_03001 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NKFPMKOK_03002 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NKFPMKOK_03003 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NKFPMKOK_03004 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKFPMKOK_03005 6e-24 - - - S - - - YqzL-like protein
NKFPMKOK_03006 2.31e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NKFPMKOK_03007 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NKFPMKOK_03008 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NKFPMKOK_03009 3.41e-144 ccpN - - K - - - CBS domain
NKFPMKOK_03010 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NKFPMKOK_03011 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NKFPMKOK_03012 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NKFPMKOK_03013 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NKFPMKOK_03014 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NKFPMKOK_03015 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NKFPMKOK_03016 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NKFPMKOK_03017 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NKFPMKOK_03018 7.12e-57 yqfQ - - S - - - YqfQ-like protein
NKFPMKOK_03019 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NKFPMKOK_03020 9.16e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NKFPMKOK_03021 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NKFPMKOK_03022 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_03023 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NKFPMKOK_03024 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NKFPMKOK_03025 3.9e-79 yqfX - - S - - - membrane
NKFPMKOK_03026 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NKFPMKOK_03027 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
NKFPMKOK_03028 8.5e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
NKFPMKOK_03029 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NKFPMKOK_03030 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NKFPMKOK_03031 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NKFPMKOK_03032 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NKFPMKOK_03033 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NKFPMKOK_03034 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NKFPMKOK_03035 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NKFPMKOK_03036 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKFPMKOK_03037 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKFPMKOK_03038 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKFPMKOK_03039 3.42e-68 yqzD - - - - - - -
NKFPMKOK_03040 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NKFPMKOK_03041 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKFPMKOK_03042 5.38e-11 yqgO - - - - - - -
NKFPMKOK_03043 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NKFPMKOK_03044 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
NKFPMKOK_03045 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NKFPMKOK_03046 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NKFPMKOK_03047 9.93e-162 yqgU - - - - - - -
NKFPMKOK_03048 1.06e-48 yqgU - - - - - - -
NKFPMKOK_03049 2.02e-63 dglA - - S - - - Thiamine-binding protein
NKFPMKOK_03050 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
NKFPMKOK_03051 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NKFPMKOK_03052 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NKFPMKOK_03053 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NKFPMKOK_03055 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKFPMKOK_03056 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NKFPMKOK_03057 1.34e-231 yqxL - - P - - - Mg2 transporter protein
NKFPMKOK_03058 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKFPMKOK_03059 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NKFPMKOK_03060 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NKFPMKOK_03061 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
NKFPMKOK_03062 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NKFPMKOK_03063 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NKFPMKOK_03064 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NKFPMKOK_03065 9.56e-35 yqzE - - S - - - YqzE-like protein
NKFPMKOK_03066 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
NKFPMKOK_03067 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
NKFPMKOK_03068 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NKFPMKOK_03069 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NKFPMKOK_03070 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NKFPMKOK_03071 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NKFPMKOK_03072 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
NKFPMKOK_03073 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKFPMKOK_03074 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NKFPMKOK_03075 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKFPMKOK_03076 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKFPMKOK_03077 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NKFPMKOK_03078 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NKFPMKOK_03079 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NKFPMKOK_03080 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NKFPMKOK_03081 8.59e-80 yqhP - - - - - - -
NKFPMKOK_03082 2.25e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
NKFPMKOK_03083 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
NKFPMKOK_03084 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NKFPMKOK_03085 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKFPMKOK_03086 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
NKFPMKOK_03087 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NKFPMKOK_03088 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NKFPMKOK_03089 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NKFPMKOK_03090 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NKFPMKOK_03091 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NKFPMKOK_03092 4.98e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NKFPMKOK_03093 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NKFPMKOK_03094 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NKFPMKOK_03095 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NKFPMKOK_03096 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NKFPMKOK_03097 5.53e-87 yqhY - - S - - - protein conserved in bacteria
NKFPMKOK_03098 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKFPMKOK_03099 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKFPMKOK_03100 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKFPMKOK_03101 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKFPMKOK_03102 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NKFPMKOK_03103 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NKFPMKOK_03104 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NKFPMKOK_03105 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NKFPMKOK_03106 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NKFPMKOK_03107 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NKFPMKOK_03108 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NKFPMKOK_03110 4.12e-258 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKFPMKOK_03113 1.65e-265 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NKFPMKOK_03115 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
NKFPMKOK_03116 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
NKFPMKOK_03118 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NKFPMKOK_03119 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NKFPMKOK_03120 9.92e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NKFPMKOK_03121 1.86e-185 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NKFPMKOK_03122 1.94e-125 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NKFPMKOK_03123 9.44e-109 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NKFPMKOK_03124 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NKFPMKOK_03125 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NKFPMKOK_03126 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NKFPMKOK_03127 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NKFPMKOK_03128 0.0 bkdR - - KT - - - Transcriptional regulator
NKFPMKOK_03129 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NKFPMKOK_03130 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NKFPMKOK_03131 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NKFPMKOK_03132 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKFPMKOK_03133 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKFPMKOK_03134 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKFPMKOK_03135 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKFPMKOK_03136 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKFPMKOK_03137 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
NKFPMKOK_03138 6.26e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NKFPMKOK_03139 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NKFPMKOK_03140 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NKFPMKOK_03141 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NKFPMKOK_03142 3.99e-118 yqjB - - S - - - protein conserved in bacteria
NKFPMKOK_03144 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NKFPMKOK_03145 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKFPMKOK_03146 5.04e-257 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NKFPMKOK_03147 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKFPMKOK_03148 1.36e-36 yqzJ - - - - - - -
NKFPMKOK_03149 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKFPMKOK_03150 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NKFPMKOK_03151 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NKFPMKOK_03152 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NKFPMKOK_03153 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NKFPMKOK_03154 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKFPMKOK_03155 7.32e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NKFPMKOK_03156 2.42e-61 - - - S - - - GlpM protein
NKFPMKOK_03157 9.08e-202 - - - K - - - LysR substrate binding domain
NKFPMKOK_03158 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKFPMKOK_03159 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NKFPMKOK_03160 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_03161 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NKFPMKOK_03162 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NKFPMKOK_03164 5.73e-206 yueF - - S - - - transporter activity
NKFPMKOK_03166 7.27e-73 - - - S - - - YolD-like protein
NKFPMKOK_03167 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKFPMKOK_03168 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NKFPMKOK_03169 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NKFPMKOK_03170 4.54e-211 yqkA - - K - - - GrpB protein
NKFPMKOK_03171 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
NKFPMKOK_03172 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
NKFPMKOK_03173 2.61e-213 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NKFPMKOK_03174 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
NKFPMKOK_03175 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NKFPMKOK_03176 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
NKFPMKOK_03177 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NKFPMKOK_03178 1.43e-271 yqxK - - L - - - DNA helicase
NKFPMKOK_03179 2.32e-75 ansR - - K - - - Transcriptional regulator
NKFPMKOK_03180 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NKFPMKOK_03181 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NKFPMKOK_03182 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NKFPMKOK_03183 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NKFPMKOK_03184 5.05e-33 - - - - - - - -
NKFPMKOK_03185 2.87e-43 yqkK - - - - - - -
NKFPMKOK_03186 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NKFPMKOK_03187 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NKFPMKOK_03188 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NKFPMKOK_03189 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NKFPMKOK_03190 4.39e-288 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NKFPMKOK_03191 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NKFPMKOK_03192 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKFPMKOK_03193 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NKFPMKOK_03194 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NKFPMKOK_03195 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKFPMKOK_03196 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NKFPMKOK_03197 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NKFPMKOK_03198 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NKFPMKOK_03199 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NKFPMKOK_03200 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NKFPMKOK_03201 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
NKFPMKOK_03202 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NKFPMKOK_03203 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NKFPMKOK_03204 3.35e-194 ypuA - - S - - - Secreted protein
NKFPMKOK_03205 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NKFPMKOK_03206 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
NKFPMKOK_03207 2.37e-124 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NKFPMKOK_03208 7.86e-68 ypuD - - - - - - -
NKFPMKOK_03209 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKFPMKOK_03210 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NKFPMKOK_03211 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NKFPMKOK_03212 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NKFPMKOK_03213 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKFPMKOK_03214 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NKFPMKOK_03216 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKFPMKOK_03217 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKFPMKOK_03218 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
NKFPMKOK_03219 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKFPMKOK_03220 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NKFPMKOK_03221 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NKFPMKOK_03222 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NKFPMKOK_03223 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NKFPMKOK_03224 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NKFPMKOK_03225 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NKFPMKOK_03226 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKFPMKOK_03227 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_03228 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_03229 6.63e-216 rsiX - - - - - - -
NKFPMKOK_03230 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKFPMKOK_03231 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NKFPMKOK_03232 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NKFPMKOK_03233 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NKFPMKOK_03234 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NKFPMKOK_03235 2.24e-124 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NKFPMKOK_03236 8.85e-110 ypbE - - M - - - Lysin motif
NKFPMKOK_03237 3.73e-109 ypbF - - S - - - Protein of unknown function (DUF2663)
NKFPMKOK_03238 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NKFPMKOK_03239 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKFPMKOK_03240 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NKFPMKOK_03241 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NKFPMKOK_03242 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NKFPMKOK_03243 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NKFPMKOK_03244 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
NKFPMKOK_03245 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
NKFPMKOK_03246 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
NKFPMKOK_03247 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NKFPMKOK_03248 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NKFPMKOK_03249 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NKFPMKOK_03250 1.32e-12 - - - S - - - YpzI-like protein
NKFPMKOK_03251 6.38e-129 yphA - - - - - - -
NKFPMKOK_03252 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NKFPMKOK_03253 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NKFPMKOK_03254 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
NKFPMKOK_03255 2.47e-166 yphF - - - - - - -
NKFPMKOK_03257 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NKFPMKOK_03258 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKFPMKOK_03259 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NKFPMKOK_03260 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NKFPMKOK_03261 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NKFPMKOK_03262 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NKFPMKOK_03263 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NKFPMKOK_03264 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NKFPMKOK_03265 8e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NKFPMKOK_03266 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKFPMKOK_03267 1.14e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKFPMKOK_03268 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NKFPMKOK_03269 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKFPMKOK_03270 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKFPMKOK_03271 1.15e-158 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NKFPMKOK_03272 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NKFPMKOK_03273 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NKFPMKOK_03274 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NKFPMKOK_03275 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKFPMKOK_03276 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NKFPMKOK_03277 3.79e-290 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NKFPMKOK_03278 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
NKFPMKOK_03279 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
NKFPMKOK_03280 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
NKFPMKOK_03281 9.23e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NKFPMKOK_03282 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NKFPMKOK_03283 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NKFPMKOK_03284 6.12e-126 ypjA - - S - - - membrane
NKFPMKOK_03285 1.09e-177 ypjB - - S - - - sporulation protein
NKFPMKOK_03286 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NKFPMKOK_03287 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NKFPMKOK_03288 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NKFPMKOK_03289 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NKFPMKOK_03290 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NKFPMKOK_03291 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NKFPMKOK_03292 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NKFPMKOK_03293 4.37e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NKFPMKOK_03294 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NKFPMKOK_03295 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NKFPMKOK_03296 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NKFPMKOK_03297 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NKFPMKOK_03298 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NKFPMKOK_03299 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NKFPMKOK_03300 2.74e-95 ypmB - - S - - - protein conserved in bacteria
NKFPMKOK_03301 1.57e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NKFPMKOK_03302 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NKFPMKOK_03303 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NKFPMKOK_03304 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKFPMKOK_03305 4.6e-113 ypoC - - - - - - -
NKFPMKOK_03306 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NKFPMKOK_03307 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKFPMKOK_03308 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
NKFPMKOK_03313 5.58e-60 yppG - - S - - - YppG-like protein
NKFPMKOK_03314 5.45e-79 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NKFPMKOK_03315 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NKFPMKOK_03316 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NKFPMKOK_03317 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NKFPMKOK_03319 8.12e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NKFPMKOK_03320 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
NKFPMKOK_03321 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NKFPMKOK_03322 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NKFPMKOK_03323 2.19e-96 yqgA - - - - - - -
NKFPMKOK_03324 6.91e-31 - - - S - - - YpzG-like protein
NKFPMKOK_03326 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NKFPMKOK_03327 1.95e-186 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NKFPMKOK_03328 1.46e-159 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NKFPMKOK_03329 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NKFPMKOK_03330 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
NKFPMKOK_03331 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
NKFPMKOK_03332 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
NKFPMKOK_03333 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
NKFPMKOK_03334 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NKFPMKOK_03335 2.25e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NKFPMKOK_03336 0.0 ypbR - - S - - - Dynamin family
NKFPMKOK_03337 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
NKFPMKOK_03338 5.97e-11 - - - - - - - -
NKFPMKOK_03339 2.07e-204 ypcP - - L - - - 5'3' exonuclease
NKFPMKOK_03341 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NKFPMKOK_03342 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NKFPMKOK_03343 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NKFPMKOK_03344 6.37e-38 ypeQ - - S - - - Zinc-finger
NKFPMKOK_03345 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
NKFPMKOK_03346 4.27e-16 degR - - - - - - -
NKFPMKOK_03347 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NKFPMKOK_03348 2.89e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NKFPMKOK_03349 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKFPMKOK_03351 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NKFPMKOK_03352 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NKFPMKOK_03353 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NKFPMKOK_03354 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NKFPMKOK_03355 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
NKFPMKOK_03356 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NKFPMKOK_03357 1.41e-142 ypjP - - S - - - YpjP-like protein
NKFPMKOK_03358 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKFPMKOK_03359 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKFPMKOK_03360 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKFPMKOK_03361 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NKFPMKOK_03362 1.54e-207 yplP - - K - - - Transcriptional regulator
NKFPMKOK_03363 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKFPMKOK_03364 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
NKFPMKOK_03365 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NKFPMKOK_03366 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NKFPMKOK_03367 2.45e-122 ypmS - - S - - - protein conserved in bacteria
NKFPMKOK_03368 3.91e-88 ypoP - - K - - - transcriptional
NKFPMKOK_03369 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKFPMKOK_03370 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NKFPMKOK_03371 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NKFPMKOK_03372 6.94e-262 yokA - - L - - - Recombinase
NKFPMKOK_03373 6.05e-22 - - - S - - - Regulatory protein YrvL
NKFPMKOK_03375 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
NKFPMKOK_03378 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NKFPMKOK_03379 2.36e-268 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NKFPMKOK_03380 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NKFPMKOK_03381 1.08e-81 cgeA - - - ko:K06319 - ko00000 -
NKFPMKOK_03382 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
NKFPMKOK_03383 1.17e-286 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NKFPMKOK_03384 3.96e-176 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NKFPMKOK_03386 3.54e-83 - - - L - - - Bacterial transcription activator, effector binding domain
NKFPMKOK_03388 2.06e-297 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKFPMKOK_03389 5.2e-156 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKFPMKOK_03390 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKFPMKOK_03391 4.03e-315 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NKFPMKOK_03392 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NKFPMKOK_03393 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NKFPMKOK_03394 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
NKFPMKOK_03395 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
NKFPMKOK_03396 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKFPMKOK_03397 1.18e-155 yodN - - - - - - -
NKFPMKOK_03399 1.97e-33 yozD - - S - - - YozD-like protein
NKFPMKOK_03400 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NKFPMKOK_03401 1.16e-72 yodL - - S - - - YodL-like
NKFPMKOK_03403 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NKFPMKOK_03404 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NKFPMKOK_03405 2.3e-30 yodI - - - - - - -
NKFPMKOK_03406 4.97e-156 yodH - - Q - - - Methyltransferase
NKFPMKOK_03407 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NKFPMKOK_03408 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_03409 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKFPMKOK_03410 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
NKFPMKOK_03411 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKFPMKOK_03412 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
NKFPMKOK_03413 5.32e-213 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NKFPMKOK_03414 1.35e-137 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NKFPMKOK_03415 6.14e-135 yodC - - C - - - nitroreductase
NKFPMKOK_03416 1.93e-69 yodB - - K - - - transcriptional
NKFPMKOK_03417 9.37e-83 iolK - - S - - - tautomerase
NKFPMKOK_03419 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NKFPMKOK_03420 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NKFPMKOK_03421 3.66e-31 - - - - - - - -
NKFPMKOK_03422 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NKFPMKOK_03423 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NKFPMKOK_03424 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKFPMKOK_03425 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NKFPMKOK_03426 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKFPMKOK_03427 2.8e-277 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NKFPMKOK_03428 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NKFPMKOK_03429 1.31e-135 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NKFPMKOK_03430 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NKFPMKOK_03431 0.0 yojO - - P - - - Von Willebrand factor
NKFPMKOK_03432 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NKFPMKOK_03433 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NKFPMKOK_03434 8.69e-156 - - - S - - - Metallo-beta-lactamase superfamily
NKFPMKOK_03435 3.02e-209 yocS - - S ko:K03453 - ko00000 -transporter
NKFPMKOK_03436 2.2e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKFPMKOK_03437 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NKFPMKOK_03438 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NKFPMKOK_03439 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NKFPMKOK_03440 4.69e-43 yozC - - - - - - -
NKFPMKOK_03442 5.32e-75 yozO - - S - - - Bacterial PH domain
NKFPMKOK_03443 5.24e-49 yocN - - - - - - -
NKFPMKOK_03444 1.46e-39 yozN - - - - - - -
NKFPMKOK_03445 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NKFPMKOK_03446 1.16e-11 yocN - - - - - - -
NKFPMKOK_03448 7.44e-78 yocK - - T - - - general stress protein
NKFPMKOK_03449 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKFPMKOK_03451 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NKFPMKOK_03452 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
NKFPMKOK_03454 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NKFPMKOK_03455 2.99e-119 yocC - - - - - - -
NKFPMKOK_03456 9.94e-172 - - - J - - - Protein required for attachment to host cells
NKFPMKOK_03457 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
NKFPMKOK_03458 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKFPMKOK_03459 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NKFPMKOK_03460 1.29e-117 yobW - - - - - - -
NKFPMKOK_03461 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NKFPMKOK_03462 1.44e-110 yobS - - K - - - Transcriptional regulator
NKFPMKOK_03463 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NKFPMKOK_03464 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NKFPMKOK_03467 1.52e-38 - - - - - - - -
NKFPMKOK_03468 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_03470 6.3e-36 yoaF - - - - - - -
NKFPMKOK_03471 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKFPMKOK_03472 2.4e-237 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKFPMKOK_03473 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NKFPMKOK_03474 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NKFPMKOK_03475 7.33e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NKFPMKOK_03477 8.96e-223 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NKFPMKOK_03478 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
NKFPMKOK_03479 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NKFPMKOK_03480 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NKFPMKOK_03481 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NKFPMKOK_03482 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NKFPMKOK_03483 6.16e-263 xylR - - GK - - - ROK family
NKFPMKOK_03484 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NKFPMKOK_03485 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NKFPMKOK_03486 1.54e-271 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NKFPMKOK_03487 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NKFPMKOK_03490 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NKFPMKOK_03491 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NKFPMKOK_03492 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NKFPMKOK_03493 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKFPMKOK_03494 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NKFPMKOK_03495 8.13e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NKFPMKOK_03496 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NKFPMKOK_03497 2.21e-132 ymaB - - S - - - MutT family
NKFPMKOK_03498 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03499 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03500 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NKFPMKOK_03501 2.31e-29 ymzA - - - - - - -
NKFPMKOK_03502 1.87e-53 - - - - - - - -
NKFPMKOK_03503 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NKFPMKOK_03504 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKFPMKOK_03505 9.08e-72 ymaF - - S - - - YmaF family
NKFPMKOK_03507 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NKFPMKOK_03508 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NKFPMKOK_03509 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NKFPMKOK_03510 3.08e-151 ymaC - - S - - - Replication protein
NKFPMKOK_03511 2.64e-07 - - - - - - - -
NKFPMKOK_03512 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NKFPMKOK_03513 9.32e-81 ymzB - - - - - - -
NKFPMKOK_03514 3.52e-149 yoaK - - S - - - Membrane
NKFPMKOK_03515 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
NKFPMKOK_03516 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NKFPMKOK_03517 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NKFPMKOK_03518 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NKFPMKOK_03519 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NKFPMKOK_03520 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NKFPMKOK_03521 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NKFPMKOK_03522 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NKFPMKOK_03523 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NKFPMKOK_03524 8.2e-306 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NKFPMKOK_03525 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NKFPMKOK_03526 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NKFPMKOK_03527 9.59e-220 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NKFPMKOK_03528 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NKFPMKOK_03529 1.97e-117 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NKFPMKOK_03530 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKFPMKOK_03531 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NKFPMKOK_03532 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
NKFPMKOK_03533 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NKFPMKOK_03534 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NKFPMKOK_03535 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKFPMKOK_03536 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NKFPMKOK_03537 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NKFPMKOK_03538 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NKFPMKOK_03539 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NKFPMKOK_03540 4.31e-260 pbpX - - V - - - Beta-lactamase
NKFPMKOK_03541 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKFPMKOK_03542 2.57e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NKFPMKOK_03543 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKFPMKOK_03544 9.2e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NKFPMKOK_03545 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
NKFPMKOK_03546 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
NKFPMKOK_03547 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NKFPMKOK_03548 2.09e-303 ymfH - - S - - - zinc protease
NKFPMKOK_03549 8.12e-300 albE - - S - - - Peptidase M16
NKFPMKOK_03550 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NKFPMKOK_03551 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_03552 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_03553 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_03554 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NKFPMKOK_03555 7.4e-41 - - - S - - - YlzJ-like protein
NKFPMKOK_03556 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NKFPMKOK_03557 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKFPMKOK_03558 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKFPMKOK_03559 3.69e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NKFPMKOK_03560 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NKFPMKOK_03561 2.43e-48 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NKFPMKOK_03563 1.16e-114 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKFPMKOK_03570 3.56e-193 - - - S - - - Calcineurin-like phosphoesterase
NKFPMKOK_03571 6.98e-31 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NKFPMKOK_03575 3.55e-106 - - - - - - - -
NKFPMKOK_03578 2.96e-35 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKFPMKOK_03579 2.42e-61 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKFPMKOK_03580 3.77e-07 - - - S - - - nucleic acid binding
NKFPMKOK_03581 5.06e-123 - - - S - - - Thymidylate synthase
NKFPMKOK_03585 3.14e-94 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NKFPMKOK_03586 6.38e-16 - - - O - - - Glutaredoxin
NKFPMKOK_03588 3.47e-55 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03589 2.83e-121 - - - L - - - HNH endonuclease
NKFPMKOK_03590 2.37e-134 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03592 2.12e-203 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03593 3.25e-48 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03594 1.15e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKFPMKOK_03595 1.22e-88 - - - S - - - NrdI Flavodoxin like
NKFPMKOK_03608 1.53e-200 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
NKFPMKOK_03609 1.87e-69 - 2.1.1.113, 2.1.1.72 - L ko:K00571,ko:K00590 - ko00000,ko01000,ko02048 N-4 methylation of cytosine
NKFPMKOK_03610 6.66e-115 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NKFPMKOK_03611 1.68e-89 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
NKFPMKOK_03614 9.77e-30 - - - S - - - protein conserved in bacteria
NKFPMKOK_03615 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NKFPMKOK_03616 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NKFPMKOK_03617 1.15e-261 - - - L - - - DNA primase activity
NKFPMKOK_03618 0.0 - - - J - - - DnaB-like helicase C terminal domain
NKFPMKOK_03619 6.62e-105 - - - - - - - -
NKFPMKOK_03620 5.25e-212 - - - L - - - AAA domain
NKFPMKOK_03621 8.57e-197 - - - - - - - -
NKFPMKOK_03627 1.2e-276 - - - M - - - Parallel beta-helix repeats
NKFPMKOK_03628 2.22e-107 - - - S - - - Pfam:DUF867
NKFPMKOK_03630 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
NKFPMKOK_03631 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NKFPMKOK_03632 1.95e-102 gerD - - - ko:K06294 - ko00000 -
NKFPMKOK_03633 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NKFPMKOK_03634 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NKFPMKOK_03635 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
NKFPMKOK_03636 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
NKFPMKOK_03637 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NKFPMKOK_03638 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKFPMKOK_03639 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NKFPMKOK_03640 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKFPMKOK_03641 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKFPMKOK_03642 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKFPMKOK_03643 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NKFPMKOK_03644 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKFPMKOK_03645 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NKFPMKOK_03646 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKFPMKOK_03647 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NKFPMKOK_03648 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKFPMKOK_03649 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NKFPMKOK_03650 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NKFPMKOK_03651 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NKFPMKOK_03652 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NKFPMKOK_03653 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NKFPMKOK_03654 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKFPMKOK_03655 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKFPMKOK_03656 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKFPMKOK_03657 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKFPMKOK_03658 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKFPMKOK_03659 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKFPMKOK_03660 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKFPMKOK_03661 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKFPMKOK_03662 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKFPMKOK_03663 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NKFPMKOK_03664 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKFPMKOK_03665 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKFPMKOK_03666 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKFPMKOK_03667 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKFPMKOK_03668 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKFPMKOK_03669 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NKFPMKOK_03670 6.11e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NKFPMKOK_03671 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKFPMKOK_03672 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NKFPMKOK_03673 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
NKFPMKOK_03674 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKFPMKOK_03675 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKFPMKOK_03676 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NKFPMKOK_03677 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NKFPMKOK_03678 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NKFPMKOK_03679 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKFPMKOK_03680 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKFPMKOK_03681 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NKFPMKOK_03682 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NKFPMKOK_03683 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKFPMKOK_03684 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NKFPMKOK_03685 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NKFPMKOK_03686 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NKFPMKOK_03687 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NKFPMKOK_03688 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NKFPMKOK_03689 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NKFPMKOK_03690 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKFPMKOK_03691 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NKFPMKOK_03692 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NKFPMKOK_03693 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NKFPMKOK_03694 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKFPMKOK_03695 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NKFPMKOK_03696 1.96e-157 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NKFPMKOK_03697 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NKFPMKOK_03698 1.22e-247 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NKFPMKOK_03699 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NKFPMKOK_03700 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NKFPMKOK_03701 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NKFPMKOK_03702 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NKFPMKOK_03703 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NKFPMKOK_03704 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
NKFPMKOK_03705 0.0 - - - I - - - PLD-like domain
NKFPMKOK_03706 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
NKFPMKOK_03707 2.29e-192 - - - S - - - membrane
NKFPMKOK_03708 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
NKFPMKOK_03709 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
NKFPMKOK_03710 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NKFPMKOK_03711 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NKFPMKOK_03712 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKFPMKOK_03713 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
NKFPMKOK_03715 4.04e-103 - - - - - - - -
NKFPMKOK_03716 2.84e-123 tnpR - - L - - - resolvase
NKFPMKOK_03717 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
NKFPMKOK_03721 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03722 7.62e-271 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NKFPMKOK_03723 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKFPMKOK_03724 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
NKFPMKOK_03725 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NKFPMKOK_03726 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NKFPMKOK_03727 1.35e-216 ybaS - - S - - - Na -dependent transporter
NKFPMKOK_03728 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
NKFPMKOK_03729 9.92e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_03730 1.48e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKFPMKOK_03731 1.12e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NKFPMKOK_03732 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NKFPMKOK_03733 4.44e-291 ybbC - - S - - - protein conserved in bacteria
NKFPMKOK_03734 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NKFPMKOK_03735 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NKFPMKOK_03736 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NKFPMKOK_03737 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NKFPMKOK_03738 1.13e-76 ybbJ - - J - - - acetyltransferase
NKFPMKOK_03739 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
NKFPMKOK_03745 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_03746 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NKFPMKOK_03747 3.01e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKFPMKOK_03748 1.1e-291 ybbR - - S - - - protein conserved in bacteria
NKFPMKOK_03749 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKFPMKOK_03750 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NKFPMKOK_03751 1.17e-21 - - - S - - - peptidyl-tyrosine sulfation
NKFPMKOK_03752 1.28e-221 - - - O - - - growth
NKFPMKOK_03753 5.91e-68 - - - S - - - ABC-2 family transporter protein
NKFPMKOK_03754 3.07e-124 ybdN - - - - - - -
NKFPMKOK_03755 9.57e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
NKFPMKOK_03756 2.34e-203 dkgB - - S - - - Aldo/keto reductase family
NKFPMKOK_03757 3.49e-134 yxaC - - M - - - effector of murein hydrolase
NKFPMKOK_03758 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NKFPMKOK_03759 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_03760 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_03761 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NKFPMKOK_03762 7.04e-226 - - - T - - - COG4585 Signal transduction histidine kinase
NKFPMKOK_03763 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NKFPMKOK_03764 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NKFPMKOK_03765 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NKFPMKOK_03766 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NKFPMKOK_03767 6.5e-33 - - - - - - - -
NKFPMKOK_03768 3.66e-103 - - - S - - - Domain of unknown function (DUF4879)
NKFPMKOK_03769 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NKFPMKOK_03770 2.99e-136 yqeB - - - - - - -
NKFPMKOK_03771 2.17e-52 ybyB - - - - - - -
NKFPMKOK_03772 0.0 ybeC - - E - - - amino acid
NKFPMKOK_03773 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
NKFPMKOK_03774 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NKFPMKOK_03775 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NKFPMKOK_03776 1e-23 - - - S - - - Protein of unknown function (DUF2651)
NKFPMKOK_03777 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NKFPMKOK_03779 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_03780 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
NKFPMKOK_03781 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NKFPMKOK_03782 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKFPMKOK_03783 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
NKFPMKOK_03784 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NKFPMKOK_03785 9.76e-52 ybfN - - - - - - -
NKFPMKOK_03786 4.36e-240 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NKFPMKOK_03787 2.61e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKFPMKOK_03788 6.73e-245 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NKFPMKOK_03789 2.38e-301 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NKFPMKOK_03790 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NKFPMKOK_03791 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NKFPMKOK_03792 7.21e-90 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NKFPMKOK_03793 4.31e-44 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NKFPMKOK_03794 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NKFPMKOK_03795 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NKFPMKOK_03796 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NKFPMKOK_03797 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NKFPMKOK_03798 3.37e-195 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKFPMKOK_03799 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NKFPMKOK_03800 1.04e-93 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NKFPMKOK_03801 1.88e-95 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NKFPMKOK_03802 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
NKFPMKOK_03803 3.11e-73 ydfQ - - CO - - - Thioredoxin
NKFPMKOK_03804 2.08e-15 - - - L - - - COG3666 Transposase and inactivated derivatives
NKFPMKOK_03805 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
NKFPMKOK_03806 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NKFPMKOK_03807 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NKFPMKOK_03808 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKFPMKOK_03809 8.33e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKFPMKOK_03810 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NKFPMKOK_03811 3.41e-241 ycbU - - E - - - Selenocysteine lyase
NKFPMKOK_03812 1.47e-305 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NKFPMKOK_03813 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NKFPMKOK_03814 1.19e-58 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKFPMKOK_03815 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKFPMKOK_03816 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
NKFPMKOK_03817 6.43e-211 yccK - - C - - - Aldo keto reductase
NKFPMKOK_03818 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
NKFPMKOK_03819 1.76e-30 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_03820 8.16e-249 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_03821 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NKFPMKOK_03822 5.55e-116 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NKFPMKOK_03823 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NKFPMKOK_03824 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NKFPMKOK_03825 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NKFPMKOK_03826 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
NKFPMKOK_03827 1.86e-62 - - - K - - - Virulence activator alpha C-term
NKFPMKOK_03828 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NKFPMKOK_03829 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NKFPMKOK_03830 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NKFPMKOK_03831 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_03832 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NKFPMKOK_03833 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NKFPMKOK_03834 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NKFPMKOK_03835 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NKFPMKOK_03836 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NKFPMKOK_03837 1.36e-245 yceH - - P - - - Belongs to the TelA family
NKFPMKOK_03838 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NKFPMKOK_03840 8.61e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NKFPMKOK_03841 2.01e-184 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NKFPMKOK_03842 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NKFPMKOK_03843 6.41e-261 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NKFPMKOK_03844 2.88e-238 ycgA - - S - - - Membrane
NKFPMKOK_03845 9.33e-31 ycgA - - S - - - Membrane
NKFPMKOK_03846 1.04e-53 ycgB - - - - - - -
NKFPMKOK_03847 2.85e-15 - - - S - - - RDD family
NKFPMKOK_03848 1.55e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NKFPMKOK_03849 0.0 mdr - - EGP - - - the major facilitator superfamily
NKFPMKOK_03850 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NKFPMKOK_03852 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NKFPMKOK_03855 4e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NKFPMKOK_03856 4.06e-178 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NKFPMKOK_03862 5.22e-05 - - - L - - - Protein of unknown function (DUF2800)
NKFPMKOK_03866 5.48e-32 - - - - - - - -
NKFPMKOK_03868 8.45e-82 - - - N - - - bacterial-type flagellum assembly
NKFPMKOK_03872 1.42e-31 - - - - - - - -
NKFPMKOK_03875 3.8e-07 - - - S - - - YopX protein
NKFPMKOK_03876 8.8e-53 - - - - - - - -
NKFPMKOK_03881 8.46e-34 - - - - - - - -
NKFPMKOK_03882 4.66e-239 - - - - - - - -
NKFPMKOK_03889 1.51e-79 - - - - - - - -
NKFPMKOK_03890 1.2e-147 yoxB - - - - - - -
NKFPMKOK_03891 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKFPMKOK_03892 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NKFPMKOK_03893 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NKFPMKOK_03894 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKFPMKOK_03895 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKFPMKOK_03896 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NKFPMKOK_03897 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NKFPMKOK_03898 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NKFPMKOK_03899 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKFPMKOK_03900 1.91e-66 - - - K - - - Helix-turn-helix domain
NKFPMKOK_03901 6.45e-238 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
NKFPMKOK_03902 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NKFPMKOK_03903 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
NKFPMKOK_03905 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NKFPMKOK_03906 1.31e-305 yoeA - - V - - - MATE efflux family protein
NKFPMKOK_03907 1.56e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NKFPMKOK_03908 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NKFPMKOK_03909 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03910 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03911 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
NKFPMKOK_03912 5.39e-82 yngL - - S - - - Protein of unknown function (DUF1360)
NKFPMKOK_03913 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NKFPMKOK_03914 2.84e-263 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NKFPMKOK_03915 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKFPMKOK_03916 6.49e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NKFPMKOK_03917 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NKFPMKOK_03918 3.73e-209 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NKFPMKOK_03919 2.97e-170 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NKFPMKOK_03920 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKFPMKOK_03921 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
NKFPMKOK_03922 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NKFPMKOK_03923 1.02e-88 yngA - - S - - - membrane
NKFPMKOK_03924 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NKFPMKOK_03925 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NKFPMKOK_03926 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKFPMKOK_03927 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NKFPMKOK_03928 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NKFPMKOK_03929 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NKFPMKOK_03930 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKFPMKOK_03931 5.28e-135 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKFPMKOK_03932 1.26e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NKFPMKOK_03933 3.84e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NKFPMKOK_03934 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03935 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03936 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKFPMKOK_03937 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NKFPMKOK_03938 2.01e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NKFPMKOK_03939 1.84e-155 - - - T - - - Transcriptional regulatory protein, C terminal
NKFPMKOK_03940 3.49e-282 - - - T - - - Histidine kinase
NKFPMKOK_03941 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
NKFPMKOK_03942 0.0 yndJ - - S - - - YndJ-like protein
NKFPMKOK_03943 2.24e-99 - - - S - - - Domain of unknown function (DUF4166)
NKFPMKOK_03944 1.56e-28 yndG - - S - - - DoxX-like family
NKFPMKOK_03945 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NKFPMKOK_03946 2.04e-60 ynfC - - - - - - -
NKFPMKOK_03947 2.21e-19 - - - - - - - -
NKFPMKOK_03948 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKFPMKOK_03949 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKFPMKOK_03950 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NKFPMKOK_03951 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NKFPMKOK_03952 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
NKFPMKOK_03953 5.95e-65 yneQ - - - - - - -
NKFPMKOK_03954 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NKFPMKOK_03955 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NKFPMKOK_03957 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NKFPMKOK_03958 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKFPMKOK_03959 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NKFPMKOK_03960 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NKFPMKOK_03961 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
NKFPMKOK_03962 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
NKFPMKOK_03963 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NKFPMKOK_03964 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NKFPMKOK_03965 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NKFPMKOK_03966 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
NKFPMKOK_03967 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NKFPMKOK_03968 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NKFPMKOK_03969 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKFPMKOK_03970 2.33e-43 ynzC - - S - - - UPF0291 protein
NKFPMKOK_03971 4.8e-141 yneB - - L - - - resolvase
NKFPMKOK_03972 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NKFPMKOK_03973 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NKFPMKOK_03975 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
NKFPMKOK_03976 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
NKFPMKOK_03977 4.12e-10 - - - - - - - -
NKFPMKOK_03978 2.53e-162 yndL - - S - - - Replication protein
NKFPMKOK_03979 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NKFPMKOK_03980 1.33e-43 - - - S - - - TM2 domain
NKFPMKOK_03981 0.0 yobO - - M - - - Pectate lyase superfamily protein
NKFPMKOK_03983 1.97e-119 yvgO - - - - - - -
NKFPMKOK_03984 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NKFPMKOK_03985 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
NKFPMKOK_03986 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKFPMKOK_03987 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
NKFPMKOK_03989 1.87e-53 - - - - - - - -
NKFPMKOK_03991 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
NKFPMKOK_03992 1.52e-164 yoaP - - K - - - YoaP-like
NKFPMKOK_03993 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NKFPMKOK_03994 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
NKFPMKOK_03995 2.04e-10 - - - - - - - -
NKFPMKOK_03996 5.82e-16 - - - - - - - -
NKFPMKOK_03997 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NKFPMKOK_03998 1.08e-86 dinB - - S - - - DinB family
NKFPMKOK_04000 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NKFPMKOK_04001 9.72e-229 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKFPMKOK_04002 9.99e-39 yazB - - K - - - transcriptional
NKFPMKOK_04003 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NKFPMKOK_04004 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKFPMKOK_04005 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKFPMKOK_04006 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NKFPMKOK_04007 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NKFPMKOK_04008 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKFPMKOK_04009 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NKFPMKOK_04010 1.22e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NKFPMKOK_04011 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NKFPMKOK_04012 6.69e-177 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NKFPMKOK_04013 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKFPMKOK_04014 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NKFPMKOK_04015 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NKFPMKOK_04016 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NKFPMKOK_04017 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NKFPMKOK_04018 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NKFPMKOK_04021 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NKFPMKOK_04022 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NKFPMKOK_04023 5.13e-129 yabQ - - S - - - spore cortex biosynthesis protein
NKFPMKOK_04024 5.47e-66 yabP - - S - - - Sporulation protein YabP
NKFPMKOK_04025 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NKFPMKOK_04026 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NKFPMKOK_04027 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKFPMKOK_04028 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NKFPMKOK_04029 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKFPMKOK_04030 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
NKFPMKOK_04031 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NKFPMKOK_04032 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NKFPMKOK_04033 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKFPMKOK_04034 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKFPMKOK_04035 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NKFPMKOK_04036 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NKFPMKOK_04037 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NKFPMKOK_04038 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NKFPMKOK_04039 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
NKFPMKOK_04040 5.32e-53 veg - - S - - - protein conserved in bacteria
NKFPMKOK_04041 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
NKFPMKOK_04042 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NKFPMKOK_04043 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NKFPMKOK_04044 3.55e-288 yabE - - T - - - protein conserved in bacteria
NKFPMKOK_04045 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NKFPMKOK_04046 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKFPMKOK_04047 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NKFPMKOK_04048 9.82e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NKFPMKOK_04049 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NKFPMKOK_04050 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NKFPMKOK_04051 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
NKFPMKOK_04052 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NKFPMKOK_04053 8.67e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NKFPMKOK_04054 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NKFPMKOK_04055 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
NKFPMKOK_04056 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKFPMKOK_04057 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NKFPMKOK_04058 6.32e-226 yaaN - - P - - - Belongs to the TelA family
NKFPMKOK_04059 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NKFPMKOK_04060 1.5e-40 csfB - - S - - - Inhibitor of sigma-G Gin
NKFPMKOK_04061 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
NKFPMKOK_04063 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
NKFPMKOK_04064 5.52e-28 - - - S - - - YopX protein
NKFPMKOK_04066 1.54e-152 yqaM - - L - - - IstB-like ATP binding protein
NKFPMKOK_04067 4.55e-36 yqaL - - L - - - DnaD domain protein
NKFPMKOK_04068 9.65e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NKFPMKOK_04069 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
NKFPMKOK_04073 3.27e-110 - - - - - - - -
NKFPMKOK_04074 4.76e-76 - - - S - - - DNA binding
NKFPMKOK_04075 2.39e-48 - - - - - - - -
NKFPMKOK_04076 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_04077 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_04078 8.41e-82 - - - - - - - -
NKFPMKOK_04079 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
NKFPMKOK_04080 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
NKFPMKOK_04081 1.16e-43 - - - L - - - Arm DNA-binding domain
NKFPMKOK_04082 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NKFPMKOK_04083 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NKFPMKOK_04084 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NKFPMKOK_04085 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NKFPMKOK_04086 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKFPMKOK_04087 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKFPMKOK_04088 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NKFPMKOK_04089 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NKFPMKOK_04090 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NKFPMKOK_04091 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKFPMKOK_04092 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NKFPMKOK_04093 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NKFPMKOK_04094 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NKFPMKOK_04095 4.4e-221 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NKFPMKOK_04114 5.85e-167 - - - L - - - Phage integrase family
NKFPMKOK_04115 1.4e-90 - - - - - - - -
NKFPMKOK_04118 6.42e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
NKFPMKOK_04119 4.18e-07 ahdIC - - K - - - PFAM helix-turn-helix domain protein
NKFPMKOK_04120 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
NKFPMKOK_04122 3.44e-116 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
NKFPMKOK_04123 2.62e-40 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NKFPMKOK_04125 2.96e-08 - - - - - - - -
NKFPMKOK_04126 4.2e-36 - - - - - - - -
NKFPMKOK_04129 2.26e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
NKFPMKOK_04132 2.89e-84 hxlR - - K - - - transcriptional
NKFPMKOK_04133 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NKFPMKOK_04134 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NKFPMKOK_04135 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
NKFPMKOK_04136 1.04e-85 nin - - S - - - Competence protein J (ComJ)
NKFPMKOK_04137 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NKFPMKOK_04138 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
NKFPMKOK_04139 3.65e-94 yckC - - S - - - membrane
NKFPMKOK_04140 2.55e-221 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKFPMKOK_04141 9.85e-281 yciC - - S - - - GTPases (G3E family)
NKFPMKOK_04142 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NKFPMKOK_04143 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKFPMKOK_04144 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NKFPMKOK_04145 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NKFPMKOK_04146 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NKFPMKOK_04147 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NKFPMKOK_04148 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKFPMKOK_04149 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKFPMKOK_04150 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NKFPMKOK_04151 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NKFPMKOK_04152 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NKFPMKOK_04153 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKFPMKOK_04154 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NKFPMKOK_04155 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
NKFPMKOK_04156 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NKFPMKOK_04157 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NKFPMKOK_04158 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NKFPMKOK_04159 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NKFPMKOK_04160 6.64e-76 ycgF - - E - - - Lysine exporter protein LysE YggA
NKFPMKOK_04161 1.15e-54 ycgF - - E - - - Lysine exporter protein LysE YggA
NKFPMKOK_04171 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NKFPMKOK_04172 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
NKFPMKOK_04173 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKFPMKOK_04174 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKFPMKOK_04175 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKFPMKOK_04176 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NKFPMKOK_04177 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NKFPMKOK_04178 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NKFPMKOK_04179 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NKFPMKOK_04180 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NKFPMKOK_04182 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NKFPMKOK_04183 9.36e-278 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NKFPMKOK_04184 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NKFPMKOK_04185 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NKFPMKOK_04186 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NKFPMKOK_04187 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NKFPMKOK_04188 1.11e-222 yaaC - - S - - - YaaC-like Protein
NKFPMKOK_04189 1.07e-57 - - - S - - - transposition, DNA-mediated
NKFPMKOK_04190 6.51e-150 - - - S - - - HTH-like domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)